******************************************************************************** MEME - Motif discovery tool ******************************************************************************** MEME version 4.0.0 (Release date: 2008-07-12 05:23:09 +1000 (Sat, 12 Jul 2008)) For further information on how to interpret these results or to get a copy of the MEME software please access http://meme.nbcr.net. This file may be used as input to the MAST algorithm for searching sequence databases for matches to groups of motifs. MAST is available for interactive use and downloading at http://meme.nbcr.net. ******************************************************************************** ******************************************************************************** REFERENCE ******************************************************************************** If you use this program in your research, please cite: Timothy L. Bailey and Charles Elkan, "Fitting a mixture model by expectation maximization to discover motifs in biopolymers", Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology, pp. 28-36, AAAI Press, Menlo Park, California, 1994. ******************************************************************************** ******************************************************************************** TRAINING SET ******************************************************************************** DATAFILE= /home/t.bailey/MEME/SVNROOT/trunk/scripts/../tests/common/lipocalin.s ALPHABET= ACDEFGHIKLMNPQRSTVWY Sequence name Weight Length Sequence name Weight Length ------------- ------ ------ ------------- ------ ------ ICYA_MANSE 1.0000 189 LACB_BOVIN 1.0000 178 BBP_PIEBR 1.0000 173 RETB_BOVIN 1.0000 183 MUP2_MOUSE 1.0000 180 ******************************************************************************** ******************************************************************************** COMMAND LINE SUMMARY ******************************************************************************** This information can also be useful in the event you wish to report a problem with the MEME software. command: meme /home/t.bailey/MEME/SVNROOT/trunk/scripts/../tests/common/lipocalin.s -text -mod zoops -protein -nostatus -nmotifs 2 -minw 8 model: mod= zoops nmotifs= 2 evt= inf object function= E-value of product of p-values width: minw= 8 maxw= 50 minic= 0.00 width: wg= 11 ws= 1 endgaps= yes nsites: minsites= 2 maxsites= 5 wnsites= 0.8 theta: prob= 1 spmap= pam spfuzz= 120 global: substring= yes branching= no wbranch= no em: prior= megap b= 4515 maxiter= 50 distance= 1e-05 data: n= 903 N= 5 sample: seed= 0 seqfrac= 1 Dirichlet mixture priors file: prior30.plib Letter frequencies in dataset: A 0.072 C 0.029 D 0.069 E 0.078 F 0.043 G 0.058 H 0.025 I 0.048 K 0.086 L 0.087 M 0.018 N 0.053 P 0.032 Q 0.029 R 0.031 S 0.059 T 0.048 V 0.070 W 0.017 Y 0.050 Background letter frequencies (from dataset with add-one prior applied): A 0.072 C 0.029 D 0.068 E 0.077 F 0.043 G 0.057 H 0.026 I 0.048 K 0.086 L 0.087 M 0.018 N 0.053 P 0.033 Q 0.029 R 0.031 S 0.059 T 0.048 V 0.069 W 0.017 Y 0.050 ******************************************************************************** ******************************************************************************** MOTIF 1 width = 26 sites = 5 llr = 244 E-value = 5.0e-006 ******************************************************************************** -------------------------------------------------------------------------------- Motif 1 Description -------------------------------------------------------------------------------- Simplified A :6::2:::::::::22:6:2::2:8: pos.-specific C 2:4::::::::::::::::::::::: probability D ::::2::::22:8::::::::::::: matrix E ::222::::2::::2::::2::4::: F :::::2:::::8::::4::::::::: G 4:::::::2:2:::::::a::::::: H 2::::::::::::::::2:::4:::: I :::2:::::::::2::2::::::42: K ::::::4:22:::2:4:::2:::::6 L ::2::::::::2:2:::::::::2:2 M ::::::::2::::::::::::::2:2 N :::::::::26:2::2:2:::::::: P :::4:::4:::::::::::::::::: Q 2:::::2:::::::2::::::::::: R :2::::2::2:::::2:::::::::: S :::2222:::::::4:::::::2::: T :::::2:4:::::::::::4::2::: V ::2:24:24::::2::2::::::2:: W :::::::::::::2::::::a2:::: Y :2::::::::::::::2::::4:::: bits 5.9 * 5.3 * 4.7 * 4.1 * * Relative 3.5 ** * ** Entropy 2.9 ** * *** ** ** * (70.4 bits) 2.3 **** **** *** ***** ** *** 1.8 ************************** 1.2 ************************** 0.6 ************************** 0.0 -------------------------- Multilevel GACPAVKPVDNFDISKFAGTWHEIAK consensus CREEDFQTGEDLNKAAIH A YALIL sequence HYLIESRVKKG LENVN E WSM M Q VSSTS MN VQRY K TV V R W -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------------------------- BBP_PIEBR 6 1.76e-24 NVYHD GACPEVKPVDNFDWSNYHGKWWEVAK YPNSVEKYGK ICYA_MANSE 7 2.29e-24 GDIFYP GYCPDVKPVNDFDLSAFAGAWHEIAK LPLENENQGK RETB_BOVIN 4 1.97e-19 ERD CRVSSFRVKENFDKARFAGTWYAMAK KDPEGLFLQD LACB_BOVIN 15 2.92e-18 LLALALTCGA QALIVTQTMKGLDIQKVAGTWYSLAM AASDISLLDA MUP2_MOUSE 17 6.60e-17 LCLGLTLVCV HAEEASSTGRNFNVEKINGEWHTIIL ASDKREKIED -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- BBP_PIEBR 1.8e-24 5_[1]_142 ICYA_MANSE 2.3e-24 6_[1]_157 RETB_BOVIN 2e-19 3_[1]_154 LACB_BOVIN 2.9e-18 14_[1]_138 MUP2_MOUSE 6.6e-17 16_[1]_138 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF 1 width=26 seqs=5 BBP_PIEBR ( 6) GACPEVKPVDNFDWSNYHGKWWEVAK 1 ICYA_MANSE ( 7) GYCPDVKPVNDFDLSAFAGAWHEIAK 1 RETB_BOVIN ( 4) CRVSSFRVKENFDKARFAGTWYAMAK 1 LACB_BOVIN ( 15) QALIVTQTMKGLDIQKVAGTWYSLAM 1 MUP2_MOUSE ( 17) HAEEASSTGRNFNVEKINGEWHTIIL 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 26 n= 778 bayes= 8.22029 E= 5.0e-006 -99 144 -149 -133 -258 269 220 -210 -126 -235 -128 -87 -179 195 -34 -79 -105 -210 -298 -234 289 -172 -248 -188 -180 -145 -158 -164 -148 -197 -97 -189 -221 -78 150 -45 -105 -120 -261 74 -84 312 -314 44 -111 -230 -180 36 -244 92 33 -225 -204 -122 -125 -133 -66 134 -214 -197 -92 -302 -187 36 -266 -208 -155 70 -160 -213 -130 -170 388 -48 -75 72 -103 -192 -332 -302 115 -282 98 109 -244 -150 -77 -177 -69 -197 -86 -77 -126 44 3 111 -51 64 -285 -236 -68 -167 -316 -260 114 -226 -183 30 -258 -72 12 -219 -200 -135 -133 94 163 231 -223 -188 -144 -348 -210 -121 -328 -216 -91 -243 200 -239 -133 -129 -194 225 247 114 -111 -243 -308 -284 -92 -241 -296 -256 -247 -224 -228 -114 -258 -190 -105 -229 361 -140 -151 -72 242 70 -329 -324 -63 -187 -232 -163 -140 75 -134 22 37 -77 241 -166 -172 -50 -40 -100 -53 221 -226 -208 -71 -310 103 103 -254 -142 -60 -205 81 -207 -94 124 -126 52 201 -34 -50 -195 -285 -234 -242 -375 91 -196 -382 91 -98 -352 -244 -408 -311 349 -242 -122 -182 -80 -157 -389 -396 -351 -318 -290 -467 -456 425 -424 -363 -172 -484 -47 -115 -430 -331 -374 -362 -296 -352 -245 -202 -103 -301 -418 363 -117 -408 -310 -244 -367 -403 -415 -323 -21 -370 -260 -284 -260 -313 -381 -414 -410 -107 -180 -350 -287 -106 -249 -200 252 -6 95 46 -249 -222 -152 -148 -153 -77 137 216 -191 96 -298 -79 114 -258 -152 -75 -202 -65 -209 -96 -73 -125 216 7 200 -40 -190 -293 -244 64 -339 -187 -115 -314 -207 -99 -238 223 -242 -134 100 -185 18 221 -102 -106 -241 -310 -282 -181 -226 -378 -340 342 -310 -122 98 -351 -88 -39 -304 -258 -227 -212 -200 -176 42 -146 170 273 -215 -127 -140 -272 -123 195 -223 -154 -247 -141 118 -194 -56 -71 -37 -96 -174 -321 -276 -199 -393 -301 -366 -446 397 -329 -419 -374 -473 -336 -252 -326 -311 -240 -221 -320 -402 -399 -453 89 -295 -91 104 -246 -153 -67 -184 77 -196 -82 -70 -123 52 29 -26 223 -176 -280 -234 -388 -388 -438 -441 -134 -384 -353 -366 -445 -245 -239 -397 -380 -302 -275 -375 -361 -359 569 -207 -290 -318 -383 -376 73 -361 354 -252 -386 -230 -173 -259 -307 -176 -201 -252 -277 -283 286 292 106 -271 -98 173 -260 -150 -94 -198 -87 -214 -101 -85 -134 26 -13 137 156 -184 -300 -255 -245 -306 -430 -410 -197 -384 -361 357 -396 52 172 -359 -346 -288 -287 -287 -197 121 -336 -320 328 -140 -375 -329 -260 -140 -310 72 -352 -199 -114 -318 -308 -242 -222 -45 -138 -72 -331 -364 -192 -313 -316 -228 -235 -288 -185 -128 276 36 217 -224 -256 -77 45 -195 -163 -176 -307 -304 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 26 nsites= 5 E= 5.0e-006 0.000000 0.200000 0.000000 0.000000 0.000000 0.400000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.400000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.200000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.200000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.400000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.200000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.200000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.200000 0.000000 0.200000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.200000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.200000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.400000 0.200000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.800000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 1 regular expression -------------------------------------------------------------------------------- [GCHQ][ARY][CELV][PEIS][ADESV][VFST][KQRS][PTV][VGKM][DEKNR][NDG][FL][DN][IKLVW][SAEQ][KANR][FIVY][AHN]G[TAEK]W[HYW][EAST][ILMV][AI][KLM] -------------------------------------------------------------------------------- Time 1.84 secs. ******************************************************************************** ******************************************************************************** MOTIF 2 width = 20 sites = 5 llr = 195 E-value = 1.3e-004 ******************************************************************************** -------------------------------------------------------------------------------- Motif 2 Description -------------------------------------------------------------------------------- Simplified A :::::::2::::::4:2::: pos.-specific C :::::::::::::::::2:6 probability D :22::::4:a:2:::::::: matrix E 4::::::::::2:::::::2 F 2::4:::::::::4::2::: G ::::::::::::::::2::: H :::2:::::::::::::2:: I :::::42:::::::24:::2 K ::2::::2:::62::::::: L :2::2:6:::::::42::2: M :::::::::::::::2::2: N 46::2:::::2:6:::2:2: P :::2::2::::::::::::: Q ::::::::::::::::2::: R :::::::::::::::::::: S :::::::2::::::::::2: T ::2:2:::a:::2::::::: V ::42:6:::::::::2:::: W ::::4::::::::::::::: Y ::::::::::8::6:::62: bits 5.9 5.3 4.7 * 4.1 ** Relative 3.5 *** * * * Entropy 2.9 * *** *** ** * * (56.1 bits) 2.3 ** **** ******** *** 1.8 ******************** 1.2 ******************** 0.6 ******************** 0.0 -------------------- Multilevel ENVFWVLDTDYKNYAIAYLC consensus NDDHLIIA NDKFLLFCME sequence FLKPN PK ET IMGHNI TVT S VN S Q Y -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 sites sorted by position p-value -------------------------------------------------------------------------------- Sequence name Start P-value Site ------------- ----- --------- -------------------- ICYA_MANSE 100 4.19e-19 MTFKFGQRVV NLVPWVLATDYKNYAINYNC DYHPDKKAHS BBP_PIEBR 96 1.08e-18 HKLTYGGVTK ENVFNVLSTDNKNYIIGYYC KYDEDKKGHQ RETB_BOVIN 101 2.46e-16 WGVASFLQKG NDDHWIIDTDYETFAVQYSC RLLNLDGTCA MUP2_MOUSE 105 5.47e-14 AGEYSVTYDG FNTFTIPKTDYDNFLMAHLI NEKDGETFQL LACB_BOVIN 105 6.21e-13 PAVFKIDALN ENKVLVLDTDYKKYLLFCME NSAEPEQSLA -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 block diagrams -------------------------------------------------------------------------------- SEQUENCE NAME POSITION P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- ICYA_MANSE 4.2e-19 99_[2]_70 BBP_PIEBR 1.1e-18 95_[2]_58 RETB_BOVIN 2.5e-16 100_[2]_63 MUP2_MOUSE 5.5e-14 104_[2]_56 LACB_BOVIN 6.2e-13 104_[2]_54 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 in BLOCKS format -------------------------------------------------------------------------------- BL MOTIF 2 width=20 seqs=5 ICYA_MANSE ( 100) NLVPWVLATDYKNYAINYNC 1 BBP_PIEBR ( 96) ENVFNVLSTDNKNYIIGYYC 1 RETB_BOVIN ( 101) NDDHWIIDTDYETFAVQYSC 1 MUP2_MOUSE ( 105) FNTFTIPKTDYDNFLMAHLI 1 LACB_BOVIN ( 105) ENKVLVLDTDYKKYLLFCME 1 // -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 position-specific scoring matrix -------------------------------------------------------------------------------- log-odds matrix: alength= 20 w= 20 n= 808 bayes= 7.32733 E= 1.3e-004 -116 -325 -64 182 136 -144 -83 -221 -110 -238 -136 235 -162 0 -39 -58 -87 -222 -290 -199 -265 -361 -4 -243 -347 -232 -89 -277 -264 -94 -248 378 -264 -137 -184 -110 -174 -332 -348 -353 -66 -251 55 -63 -218 -174 -93 -64 47 -162 -65 -96 -142 12 -3 -58 128 212 -277 -241 -125 -208 -290 -239 294 -248 179 -55 -244 -93 -23 -219 151 -123 -126 -139 -115 66 -140 111 -162 -256 -284 -238 -116 -257 -185 -103 -231 -1 -60 23 -238 -121 -123 -152 71 -126 495 -171 -187 -259 -460 -432 -253 -411 -393 294 -444 -100 -72 -409 -350 -345 -317 -333 -179 284 -423 -402 -241 -288 -462 -383 -126 -379 -302 114 -383 294 55 -375 97 -218 -225 -287 -207 -90 -286 -303 87 -310 199 -27 -267 -139 -74 -219 69 -226 -114 -38 -135 29 -1 118 -60 -209 -301 -248 -211 -289 -379 -410 -366 -321 -325 -239 -365 -355 -194 -226 -304 -238 -240 -26 413 -240 -397 -434 -314 -426 368 -127 -416 -332 -262 -376 -425 -423 -332 -102 -381 -278 -298 -284 -334 -389 -420 -421 -225 -294 -274 -298 78 -282 -38 -226 -307 -220 -157 120 -267 -192 -179 -191 -229 -254 -84 364 -140 -422 109 152 -378 -212 -152 -292 227 -299 -190 -123 -188 10 -34 -125 -141 -275 -395 -345 -219 -352 -147 -205 -340 -210 -87 -272 -9 -326 -217 360 -238 -85 -82 -95 66 -308 -341 -333 -252 -295 -377 -356 284 -344 -34 -222 -366 -206 -151 -294 -288 -226 -210 -233 -263 -256 -56 339 187 -212 -423 -354 -120 -291 -268 186 -351 201 35 -320 -273 -212 -215 -200 -131 -4 -258 -258 -245 -306 -430 -410 -197 -384 -361 357 -396 52 172 -359 -346 -288 -287 -287 -197 121 -336 -320 101 -261 -102 -53 108 107 -47 -152 -62 -172 -64 119 -120 207 16 -25 -39 -150 -255 -163 -160 114 -292 -265 138 -273 186 -163 -284 -166 -94 -236 -216 -168 -142 -153 -188 -190 -62 335 -70 -186 -203 -142 -27 -188 -50 -16 -146 73 243 97 -158 -34 -48 101 -41 -46 -170 156 -296 492 -485 -201 -374 -433 -397 -95 -465 -326 -236 -426 -407 -347 -325 -347 -285 -274 -475 -467 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 position-specific probability matrix -------------------------------------------------------------------------------- letter-probability matrix: alength= 20 w= 20 nsites= 5 E= 1.3e-004 0.000000 0.000000 0.000000 0.400000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.600000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 1.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.800000 0.000000 0.000000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.400000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.400000 0.000000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.200000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.600000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.200000 0.200000 0.200000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.200000 0.000000 0.600000 0.000000 0.200000 0.000000 0.000000 0.000000 0.200000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 0.000000 -------------------------------------------------------------------------------- -------------------------------------------------------------------------------- Motif 2 regular expression -------------------------------------------------------------------------------- [ENF][NDL][VDKT][FHPV][WLNT][VI][LIP][DAKS]TD[YN][KDE][NKT][YF][ALI][ILMV][AFGNQ][YCH][LMNSY][CEI] -------------------------------------------------------------------------------- Time 3.27 secs. ******************************************************************************** ******************************************************************************** SUMMARY OF MOTIFS ******************************************************************************** -------------------------------------------------------------------------------- Combined block diagrams: non-overlapping sites with p-value < 0.0001 -------------------------------------------------------------------------------- SEQUENCE NAME COMBINED P-VALUE MOTIF DIAGRAM ------------- ---------------- ------------- ICYA_MANSE 2.35e-36 6_[1(2.29e-24)]_67_[2(4.19e-19)]_70 LACB_BOVIN 2.62e-24 14_[1(2.92e-18)]_64_[2(6.21e-13)]_54 BBP_PIEBR 3.76e-36 5_[1(1.76e-24)]_64_[2(1.08e-18)]_58 RETB_BOVIN 8.78e-29 3_[1(1.97e-19)]_71_[2(2.46e-16)]_63 MUP2_MOUSE 5.29e-24 16_[1(6.60e-17)]_62_[2(5.47e-14)]_56 -------------------------------------------------------------------------------- ******************************************************************************** ******************************************************************************** Stopped because nmotifs = 2 reached. ******************************************************************************** CPU: tlb-sayonara.imb.uq.edu.au ********************************************************************************