Description

The Twinscan program predicts genes in a manner similar to Genscan, except that Twinscan takes advantage of genome comparisons to improve gene prediction accuracy. In the version of Twinscan used to generate this track, intronless copies of known genes are masked out before gene prediction, reducing the number of non-processed pseudogenes in gene models. More information and a web server can be found at http://mblab.wustl.edu/.

Display Conventions and Configuration

This track follows the display conventions for gene prediction tracks.

The track description page offers the following filter and configuration options:

• Color track by codons: Select the genomic codons option to color and label each codon in a zoomed-in display to facilitate validation and comparison of gene predictions. Click the Help on codon coloring link on the track description page for more information about this feature.

Methods

The Twinscan algorithm is described in Korf, I. et al. 2001 in the References section below.

Credits

Thanks to Michael Brent's Computational Genomics Group at Washington University St. Louis for providing these data.

References

Korf I, Flicek P, Duan D, Brent MR. Integrating genomic homology into gene structure prediction. Bioinformatics. 2001 Jun 1;17(90001)S140-8.