Description

This annotation consolidates regulatory regions from ORegAnno and locus experts. ORegAnno holds literature-curated regulatory elements and mutations (mutations not included in this track).

Display Conventions and Configuration

The display may be filtered to show regulatory, promoter, enhancer, or hypersensitive sites. To exclude certain types of regions from the display, check the appropriate boxes in the "Exclude region type" list at the top of the description page.

Methods

The information shown in this track was compiled from data provided by ORegAnno, Laura Elnitski, Ross Hardison, Doug Higgs, and Jim Hughes (see Credits). Refer to Elnitski et al. (2003) in the References section for more information.

Credits

Belinda Giardine, Ross Hardison, Webb Miller, Cathy Riemer

Center for Comparative Genomics and Bioinformatics, Penn State University, University Park, PA

Fan Hsu, Jim Kent, Andrew Kern, Robert Kuhn, Heather Trumbower

Center for Biomolecular Science and Engineering, University of California, Santa Cruz, CA

The ORegAnno community (please see individual citations for various features)

ORegAnno

Laura Elnitski

National Human Genome Research Institute, Rockville, MD

Richard Gibbons, Doug Higgs, Jim Hughes

Weatherall Institute of Molecular Medicine, Oxford UK

Garry Cutting, Andrew P. Feinberg

Johns Hopkins University School of Medicine, Baltimore, MD

References

Elnitski, L., Hardison, R.C., Li, J., Yang, S., Kolbe, D., Eswara, P., O'Connor, M.J., Schwartz, S., Miller, W. and Chiaromonte, F. Distinguishing regulatory DNA from neutral sites. Genome Res. 13(1):64-72 (2003).

Montgomery S.B., Griffith O.L., Sleumer M.C., Bergman C.M., Bilenky M., Pleasance E.D., Prychyna Y., Zhang X., Jones S.J.M. ORegAnno: An open access database and curation system for literature-derived promoters, transcription factor binding sites, and regulatory variation. Bioinformatics. 22(5):637-40 (2006).