Description
These tracks display microarray data hybridized to the
Affymetrix Human Exon 1.0 GeneChip. In
contrast to traditional microarrays, which are designed to measure
overall gene expression, the Affymetrix exon arrays contain separate
probesets for each exon. This allows large-scale measurement of
alternative splicing, alternative polyadenylation, and alternative
promoter usage. Additionally, analysis of the constitutive exons
(those included in all transcripts) offer accurate measurement of
overall gene expression levels. Further information on the
design and content of exon arrays can be found here.
Display Conventions
Items on these tracks represent exon array probesets. For
information regarding specific microarray probesets, turn on the Affy
Exon Probes track, which can be found inside the Affy
Exon supertrack in the Expression track group.
Credits
These data were generated and analyzed as part of the ENCODE project, a
genome-wide consortium project with the aim of cataloging all
functional elements in the human genome. This effort includes
collecting a variety of data over a specific set of cell types.
Consequently,
data
related to these tracks be available under ENCODE
tracks.
References
Gardina PJ, Clark TA, Shimada B, Staples MK, Yang Q, Veitch J,
Schweitzer A, Awad T, Sugnet C, Dee S, Davies C, Williams A, Turpaz Y. Alternative
splicing and differential gene expression in colon cancer detected by a
whole genome exon array. BMC Genomics. 2006 Dec 27;7:325.
Bemmo A, Benovoy D, Kwan T, Gaffney DJ, Jensen RV, Majewski J. Gene expression and isoform variation
analysis using Affymetrix Exon Arrays. BMC Genomics. 2008
Nov 7;9:529.
Data Release Policy
Data users may freely use ENCODE data, but may not, without prior
consent, submit publications that use an unpublished ENCODE dataset
until nine months following the release of the dataset. This date is
listed in the Restricted Until column on the track configuration page
and the download page. The full data release policy for ENCODE is
available here.