Description

This column shows the H-Invitational Gene Database (HInv-DB) ID associated with the gene, if available.

The HInv-DB is a human gene database containing human-curated annotation of 41,118 full-length cDNA clones representing 21,037 cDNA clusters. The project was initiated in 2002 and the database became publicly available in April 2004.

HInv-DB entries describe the following entities:

• gene structures
• functions
• novel alternative splicing isoforms
• non-coding functional RNAs
• functional domains
• sub-cellular localizations
• metabolic pathways
• predictions of protein 3D structure
• mapping of SNPs and microsatellite repeat motifs in relation with orphan diseases
• gene expression profiling
• comparative results with mouse full-length cDNAs gene structures

A full description of the construction of the HInv-DB is contained in the report by the H-Inv Consortium (see References section).

Action

Credits

The H-InvDB is hosted at the Japan Biological Information Research Center (JBIRC). The human-curated annotations were produced during invitational annotation meetings held in Japan during the summer of 2002, with a follow-up meeting in November 2004. Participants included 158 scientists representing 67 institutions from 12 countries.

The full-length cDNA clones and sequences were produced by the Chinese National Human Genome Center (CHGC), the Deutsches Krebsforschungszentrum (DKFZ/MIPS), Helix Research Institute, Inc. (HRI), the Institute of Medical Science in the University of Tokyo (IMSUT), the Kazusa DNA Research Institute (KDRI), the Mammalian Gene Collection (MGC/NIH) and the "Full-Length Long Japan" (FLJ) project.

References

Imanishi T, et al. Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones. PLoS Biol. 2004;2(6):e162.