/* bwgInternal - stuff to create and use bigWig files. Generally you'll want to use the * simpler interfaces in the bigWig module instead. This file is good reading though * if you want to extend the bigWig interface, or work with bigWig files directly * without going through the Kent library. */ #ifndef BIGWIGFILE_H #define BIGWIGFILE_H enum bwgSectionType /* Code to indicate section type. */ { bwgTypeBedGraph=1, bwgTypeVariableStep=2, bwgTypeFixedStep=3, }; struct bwgBedGraphItem /* An bedGraph-type item in a bwgSection. */ { struct bwgBedGraphItem *next; /* Next in list. */ bits32 start,end; /* Range of chromosome covered. */ float val; /* Value. */ }; struct bwgVariableStepItem /* An variableStep type item in a bwgSection. */ { struct bwgVariableStepItem *next; /* Next in list. */ bits32 start; /* Start position in chromosome. */ float val; /* Value. */ }; struct bwgVariableStepPacked /* An variableStep type item in a bwgSection. */ { bits32 start; /* Start position in chromosome. */ float val; /* Value. */ }; struct bwgFixedStepItem /* An fixedStep type item in a bwgSection. */ { struct bwgFixedStepItem *next; /* Next in list. */ float val; /* Value. */ }; struct bwgFixedStepPacked /* An fixedStep type item in a bwgSection. */ { float val; /* Value. */ }; union bwgItem /* Union of item pointers for all possible section types. */ { struct bwgBedGraphItem *bedGraphList; /* A linked list */ struct bwgFixedStepPacked *fixedStepPacked; /* An array */ struct bwgVariableStepPacked *variableStepPacked; /* An array */ /* No packed format for bedGraph... */ }; struct bwgSection /* A section of a bigWig file - all on same chrom. This is a somewhat fat data * structure used by the bigWig creation code. See also bwgSection for the * structure returned by the bigWig reading code. */ { struct bwgSection *next; /* Next in list. */ char *chrom; /* Chromosome name. */ bits32 start,end; /* Range of chromosome covered. */ enum bwgSectionType type; union bwgItem items; /* List/array of items in this section. */ bits32 itemStep; /* Step within item if applicable. */ bits32 itemSpan; /* Item span if applicable. */ bits16 itemCount; /* Number of items in section. */ bits32 chromId; /* Unique small integer value for chromosome. */ bits64 fileOffset; /* Offset of section in file. */ }; struct bwgSectionHead /* A header from a bigWig file section - similar to above bug what is on disk. */ { bits32 chromId; /* Chromosome short identifier. */ bits32 start,end; /* Range covered. */ bits32 itemStep; /* For some section types, the # of bases between items. */ bits32 itemSpan; /* For some section types, the # of bases in each item. */ UBYTE type; /* Type byte. */ UBYTE reserved; /* Always zero for now. */ bits16 itemCount; /* Number of items in block. */ }; void bwgSectionHeadFromMem(char **pPt, struct bwgSectionHead *head, boolean isSwapped); /* Read section header. */ int bwgSectionCmp(const void *va, const void *vb); /* Compare to sort based on chrom,start,end. */ struct bwgSection *bwgParseWig( char *fileName, /* Name of ascii wig file. */ boolean clipDontDie, /* Skip items outside chromosome rather than aborting. */ struct hash *chromSizeHash, /* If non-NULL items checked to be inside chromosome. */ int maxSectionSize, /* Biggest size of a section. 100 - 100,000 is usual range. */ struct lm *lm); /* Memory pool to allocate from. */ /* Parse out ascii wig file - allocating memory in lm. */ int bwgAverageResolution(struct bwgSection *sectionList); /* Return the average resolution seen in sectionList. */ struct bbiSummary *bwgReduceSectionList(struct bwgSection *sectionList, struct bbiChromInfo *chromInfoArray, int reduction); /* Return summary of section list reduced by given amount. */ void bwgCreate(struct bwgSection *sectionList, struct hash *chromSizeHash, int blockSize, int itemsPerSlot, boolean doCompress, char *fileName); /* Create a bigWig file out of a sorted sectionList. A lower level routine * than the one above. */ #endif /* BIGWIGFILE_H */