/* sufa - suffix array for genome. Use sufaMake utility to create one of these, and * the routines here to access it. See comment by sufaFileHeader for file format. */ /* This file is copyright 2008 Jim Kent, but license is hereby * granted for all use - public, private or commercial. */ #ifndef SUFA_H #define SUFA_H struct sufaFileHeader /* Short read index file binary file header. A sufa file starts with this fixed 128 byte * structure. It is followed by the following sections: * chromosome name strings - zero terminated. Padded with zero to 4 byte boundary * chromosome sizes (32 bits each) * chromosome DNA - one byte per base lower case. A zero between each chrom, and a zero before * and after (to make some end conditions easier). Padded if need be with * additional zeroes to 4 base boundary. * suffixArray - 32 bits for each indexed base */ { bits32 magic; /* Always SUFA_MAGIC */ bits16 majorVersion; /* This version changes when backward compatibility breaks. */ bits16 minorVersion; /* This version changes whenever a feature is added. */ bits64 size; /* Total size to memmap, including header. */ bits32 chromCount; /* Total count of chromosomes/contigs in file. */ bits32 chromNamesSize; /* Size of names of all contigs (including zeroes at end), padded to 4 byte boundary as needed). */ bits64 arraySize; /* Total number of bases actually indexed (non-N, unmasked). */ bits64 dnaDiskSize; /* Size of DNA on disk with zero separators. Padded to 4 byte boundary */ bits64 reserved[11];/* All zeroes for now. */ }; struct sufa /* Suffix array in memory */ { struct sufa *next; boolean isMapped; /* True if memory mapped. */ struct sufaFileHeader *header; /* File header. */ char **chromNames; /* Name of each chromosome. */ bits32 *chromSizes; /* Size of each chromosome. No deallocation required (in memmap) */ bits32 *chromOffsets; /* Offset of each chromosome's DNA */ char *allDna; /* All DNA from each contig/chromosome with zero separators. */ bits32 *array; /* Alphabetized offsets into allDna. */ }; struct sufa *sufaRead(char *fileName, boolean memoryMap); /* Read in a sufa from a file. Does this via memory mapping if you like, * which will be faster typically for about 100 reads, and slower for more * than that (_much_ slower for thousands of reads and more). */ void sufaFree(struct sufa **pSufa); /* Free up resources associated with index. */ int sufaOffsetToChromIx(struct sufa *sufa, bits32 tOffset); /* Figure out index of chromosome containing tOffset */ /** Stuff to define SUFA files **/ #define SUFA_MAGIC 0x6727B283 /* Magic number at start of SUFA file */ #define SUFA_MAJOR_VERSION 0 #define SUFA_MINOR_VERSION 0 #endif /* SUFA_H */