/* sufx - suffix array with traversal extension for genome. Use sufxMake utility to * create one of these files , and the routines here to access it. See comment by * sufxFileHeader for file format. See src/shortReads/sufxMake/sufx.doc as well for * an explanation of the data structures, particularly the traverse array. */ /* This file is copyright 2008 Jim Kent, but license is hereby * granted for all use - public, private or commercial. */ #ifndef SUFX_H #define SUFX_H struct sufxFileHeader /* Short read index file binary file header. A sufx file starts with this fixed 128 byte * structure. It is followed by the following sections: * chromosome name strings - zero terminated. Padded with zero to 4 byte boundary * chromosome sizes (32 bits each) * chromosome DNA - one byte per base lower case. A zero between each chrom, and a zero before * and after (to make some end conditions easier). Padded if need be with * additional zeroes to 4 base boundary. * suffix array - 32 bits for each indexed base. Alphabetical offsets into DNA * traverse array - Also 32 bits per indexed base. Helper info to traverse array like a tree. */ { bits32 magic; /* Always SUFX_MAGIC */ bits16 majorVersion; /* This version changes when backward compatibility breaks. */ bits16 minorVersion; /* This version changes whenever a feature is added. */ bits64 size; /* Total size to memmap, including header. */ bits32 chromCount; /* Total count of chromosomes/contigs in file. */ bits32 chromNamesSize; /* Size of names of all contigs (including zeroes at end), padded to 4 byte boundary as needed). */ bits64 arraySize; /* Total number of bases actually indexed (non-N, unmasked). */ bits64 dnaDiskSize; /* Size of DNA on disk with zero separators. Padded to 4 byte boundary */ bits64 reserved[11];/* All zeroes for now. */ }; struct sufx /* Suffix array in memory */ { struct sufx *next; boolean isMapped; /* True if memory mapped. */ struct sufxFileHeader *header; /* File header. */ char **chromNames; /* Name of each chromosome. */ bits32 *chromSizes; /* Size of each chromosome. No deallocation required (in memmap) */ bits32 *chromOffsets; /* Offset of each chromosome's DNA */ char *allDna; /* All DNA from each contig/chromosome with zero separators. */ bits32 *array; /* Alphabetized offsets into allDna. */ bits32 *traverse; /* Offsets to position in array where current prefix changes. */ }; struct sufx *sufxRead(char *fileName, boolean memoryMap); /* Read in a sufx from a file. Does this via memory mapping if you like, * which will be faster typically for about 100 reads, and slower for more * than that (_much_ slower for thousands of reads and more). */ void sufxFree(struct sufx **pSufx); /* Free up resources associated with index. */ int sufxOffsetToChromIx(struct sufx *sufx, bits32 tOffset); /* Figure out index of chromosome containing tOffset */ /** Stuff to define SUFX files **/ #define SUFX_MAGIC 0x600BA3A1 /* Magic number at start of SUFX file */ #define SUFX_MAJOR_VERSION 0 #define SUFX_MINOR_VERSION 0 #endif /* SUFX_H */