1 AP-2alpha AP2ALPHA AP-2alpha Rabbit polyclonal - AP-2alpha (H-79) is a rabbit polyclonal antibody raised against amino acids 130-209 mapping within an internal region of AP-2alpha of human origin. Antibody Target: AP-2alpha Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5' -GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle (by similarity). Santa Cruz Biotech sc-8975 http://www.scbt.com/datasheet-8975-ap-2alpha-h-79-antibody.html Farnham GeneCard:TFAP2A http://www.genecards.org/cgi-bin/carddisp.pl?gene=TFAP2A Human_-_AP-2alpha_(siRNA,ChIP):human_AP-2alpha_validation_Farnham.pdf AP-2alpha (sc-8975) 2 AP-2gamma AP2GAMMA AP-2gamma Rabbit polyclonal - AP-2Y (H-77) is a rabbit polyclonal antibody raised against amino acids 145-221 mapping with in an internal region of AP-2Y of human origin. Antibody Target: AP-2gamma Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Santa Cruz Biotech sc-8977 http://www.scbt.com/datasheet-8977-ap-2gamma-h-77-antibody.html Farnham GeneCard:GTFAP2C http://www.genecards.org/cgi-bin/carddisp.pl?gene=TFAP2C Human_-_AP-2alpha_(siRNA,ChIP):human_AP-2alpha_validation_Farnham.pdf AP-2gamma (sc-8977) 3 ARID3A_(NB100-279) ARID3ANB100279 ARID3A Rabbit polyclonal, Immunogen: A synthetic peptide, which represented a portion of human Dead Ringer-Like 1 encoded within exon 8. Antibody Target: ARID3A This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. (provided by RefSeq) Novus Biologicals NB100-279 http://www.novusbio.com/DRIL1-Antibody_NB100-279.html Snyder GeneCard:ARID3A http://www.genecards.org/cgi-bin/carddisp.pl?gene=ARID3A Human_-_ARID3A_(NB100-279)(Immunoprecipitation,ChIP):human_ARID3A_NB100-279_validation_Snyder.pdf ARID3A (NB100-279) A1 4 ARID3A_(sc-8821) ARID3ASC8821 ARID3A affinity purified goat polyclonal antibody raised against a peptide mapping at the N-terminus of ARID3A of human origin. Antibody Target: ARID3A This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. (provided by RefSeq) Santa Cruz Biotech sc-8821 http://www.scbt.com/datasheet-8821-arid3a-n-20-antibody.html Snyder GeneCard:ARID3A http://www.genecards.org/cgi-bin/carddisp.pl?gene=ARID3A Human_-_ARID3A_(sc-8821)(Immunoprecipitation,ChIP):human_ARID3A_sc-8821_validation_Snyder.pdf ARID3A (sc-8821) B100 5 ATF1_(06-325) ATF106325 ATF1 Sheep polyclonal, immunogen: CPVTLTSQTTKTDDPQL. Antibody Target: ATF1 ATF1 is a bZip transcription factor from the CREB family. ATF1 binds to both cAMP response elements (TGACGTCA). Millipore 06-325 http://www.millipore.com/coa/tech1/74jm6a Struhl GeneCard:ATF1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ATF1 Human_-_ATF1_(06-325)(Western_blot,ChIP):human_ATF1_06-325_validation_Struhl.pdf ATF1 (06-325) 6 ATF2_(9221) ATF29221 ATF2 Rabbit polyclonal, antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr71 of human ATF2. Antibodies are purified by protein A and peptide affinity chromatography. Antibody Target: ATF2 ATF2 is a stress inducible basic leucine zipper transcription factor from the CREB family. ATF2 is phosphorylated at threonine residues 69 and 71 by JNK or p38 mitogen activated protein kinases. Mutation of these residues leads to the loss of ATF2 transactivation in vitro. Cell Signaling 9221 http://www.cellsignal.com/products/9221.html Struhl GeneCard:ATF2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ATF2 Human_-_ATF2_(9221)(Western_blot,Immunoprecipitation):human_ATF2_9221_validation_Struhl.pdf ATF2 (9221) 7 ATF2_(sc-6233) ATF2SC6233 ATF2 Rabbit polyclonal, epitope corresponding to amino acids 1-96 mapping at the N-terminus of ATF-2 of human origin. Antibody Target: ATF2 ATF2 is a bZip transcription factor from the CREB family. ATF2 binds to both cAMP response elements (TGACGTCA) and TPA responsive element (TGAGTCA) and is known to heterodimerize with JUN members of the AP1 family of transcription factors. ATF2 is activated by phosphorylation of Thr71 by the stress activated p38 mitogen activated protein kinases. Santa Cruz Biotech sc-6233 http://www.scbt.com/datasheet-6233-atf-2-n-96-antibody.html Struhl GeneCard:ATF2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ATF2 Human_-_ATF2_(sc-6233)(Western_blot,ChIP):human_ATF2_sc-6233_validation_Struhl.pdf ATF2 (sc-6233) 8 ATF2_(SC-81188) ATF2SC81188 ATF2 Mouse monoclonal IgG, raised against a recombinant protein corresponding to an internal region of ATF2 of human origin. Antibody Target: ATF2 This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. (provided by RefSeq) Santa Cruz Biotech sc-81188 http://www.scbt.com/datasheet-81188-atf-2-atf25i062-antibody.html Myers GeneCard:ATF2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ATF2 Human_-_ATF2_(SC-81188)(Western_blot,IP-MassSpec):human_ATF2_SC-81188_sc-81188_validation_Myers.pdf ATF2 (sc-81188) A1111 9 ATF3 ATF3 ATF3 Rabbit polyclonal IgG, epitope mapping at the C-terminus of ATF3 of human origin. Antibody Target: ATF3 Activating transcription factor 3. A bZIP transcription factor and member of the Ca2+/cAMP response element-binding (CREB) protein family. ATF3 is found to act both as an activator and repressor of transcription. Santa Cruz Biotech sc-188 http://www.scbt.com/datasheet-188-atf-3-c-19-antibody.html Myers GeneCard:ATF3 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ATF3 Human_-_ATF3(Immunoblot):human_ATF3_validation_Myers.pdf ATF3 (sc-188) J2209, E1406 10 Bach1_(sc-14700) BACH1SC14700 Bach1 BACH1 (C-20) is an affinity purified goat polyclonal antibody raised against a peptide mapping near the C-terminus of BACH1 of human origin. Antibody Target: Bach1 This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. (provided by RefSeq) Santa Cruz Biotech sc-14700 http://www.scbt.com/datasheet-14700-bach1-c-20-antibody.html Snyder GeneCard:BACH1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BACH1 Human_-_Bach1_(sc-14700)(Immunoblots,IP-Mass_spec):human_Bach1_sc-14700_validation_Snyder.pdf Bach1 (sc-14700) E1503 11 BAF155 BAF155 BAF155 BAF155 (H-76) is a rabbit polyclonal antibody raised against amino acids 998-1073 of BAF155 of human origin. Antibody Target: BAF155 BAF155 (SMARCC1, Brg1-Associated Factor, 155 kD) is a ubiquitous component of the SWI/SNF chromatin-remodeling complex. Santa Cruz Biotech sc-10756 http://www.scbt.com/datasheet-10756-baf155-h-76-antibody.html Snyder GeneCard:SMARCC1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=SMARCC1 Human_-_BAF155(Immunoprecipitation,IP-Mass_spec):human_BAF155_validation_Snyder.pdf BAF155 (sc-10756) 12 BAF170 BAF170 BAF170 BAF170 (H-116) is a rabbit polyclonal antibody raised against amino acids 1093-1208 of BAF170 of human origin. Antibody Target: BAF170 BAF170 (Brg1-Associated Factor, 170 kD) is a ubiquitous component of the SWI/SNF chromatin-remodeling complex. Santa Cruz Biotech sc-10757 http://www.scbt.com/datasheet-10757-baf170-h-116-antibody.html Snyder GeneCard:SMARCC2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=SMARCC2 Human_-_BAF170(Immunoprecipitation,IP-Mass_spec):human_BAF170_validation_Snyder.pdf BAF170 (sc-10757) 13 BATF BATF BATF Mouse monoclonal. Raised against recombinant B-ATF of human origin. Recommended for detection of B-ATF of m, r and h origin by WB, IP and ELISA. Antibody Target: BATF The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events. Santa Cruz Biotech sc-100974 http://www.scbt.com/datasheet-100974-b-atf-ww8-antibody.html Myers GeneCard:BATF http://www.genecards.org/cgi-bin/carddisp.pl?gene=BATF Human_-_:missing BATF (sc-100974) 14 BCL11A BCL11A BCL11A Mouse monoclonal [18B12DE6] to Ctip1. Raised against a cocktail of BCL11A fusion proteins. Reacts with human and mouse. Tested for ICC/IF, IHC-P, IP, WB. Antibody Target: BCL11A This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis,is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity) Abcam ab19489 http://www.abcam.com/Ctip1-antibody-18B12DE6-ab19489.html Myers GeneCard:BCL11A http://www.genecards.org/cgi-bin/carddisp.pl?gene=BCL11A Human_-_:missing BCL11A (ab19489) 15 BCL11A_(SC-56011) BCL11ASC56011 BCL11A Mouse monoclonal IgG, raised against BCL11A of human origin. Antibody Target: BCL11A This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. (provided by RefSeq) Santa Cruz Biotech sc-56011 http://www.scbt.com/datasheet-56011-bcl-11a-14b5-antibody.html Myers GeneCard:BCL11A http://www.genecards.org/cgi-bin/carddisp.pl?gene=BCL11A Human_-_BCL11A_(SC-56011)(Western_blot,IP-Mass_Spec):human_BCL11A_SC-56011_validation_Myers.pdf BCL11A (sc-56011) B2811 16 BCL3 BCL3 BCL3 Bcl-3(C-14) is an affinity purified rabbit polyclonal antibody raised against a peptide mapping at the C-terminus of Bcl-3 of human origin. Recommended for detection of Bcl-3 of m, r and h origin by WB, IP, IF and ELISA. Antibody Target: BCL3 This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. (Provided by RefSeq). Santa Cruz Biotech sc-185 http://www.scbt.com/datasheet-185-bcl-3-c-14-antibody.html Myers GeneCard:BCL3 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BCL3 Human_-_BCL3(Immunoblot):human_BCl3_C-14_validation_Myers.pdf BCL3 (sc-185) 17 BCLAF1_(SC-101388) BCLAF1 BCLAF1 Mouse monoclonal IgG, raised against a synthetic peptide corresponding to a.a. 900-909 of BCLAF1 of human origin. Antibody Target: BCLAF1 This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins (RefSeq). Santa Cruz Biotech sc-101388 http://www.scbt.com/datasheet-101388-bclaf1-m33-p5b11-antibody.html Myers GeneCard:BCLAF1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BCLAF1 Human_-_BCLAF1(Immunoblot):human_BCLAF1_SC101388_validation_Myers.pdf BCLAF1 (sc-101388) 18 BDP1 BDP1 BDP1 Rabbit polyclonal - Antiserum 2663 was raised by immunizing rabbits with synthetic peptide CSDRYRIYKAQKLRE (human Bdp1 residues 139?153) coupled to KLH. Antibody Target: BDP1 'B double-prime 1', subunit of RNA polymerase III transcription initiation factor IIIB Donated by Dr. RJ White, The Beatson Institute for Cancer Research 2663 http://www.beatson.gla.ac.uk/Regulation-of-Cancer-Cell-Proliferation-and-Growth/Robert-J-White-Gene-Transcription.html Struhl GeneCard:BDP1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BDP1 Human_-_:missing BDP1 (2663) 19 BHLHE40 BHLHE40 BHLHE40 Dec-1(S-8) is a mouse monoclonal IgG2b antibody raised against recombinant DEC1 of human origin. Recommended for detection of DEC1 of m and h origin by WB, IP and ELISA. Antibody Target: BHLHE40 This gene encodes a basic helix-loop-helix protein expressed in various tissues. Expression in the chondrocytes is responsive to the addition of Bt2cAMP. The encoded protein is believed to be involved in the control of cell differe Santa Cruz Biotech sc-101023 http://www.scbt.com/datasheet-101023-dec1-s-8-antibody.html Myers GeneCard:BHLHE40 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BHLHE40 Human_-_BHLEH40(Immunoblot):human_BHLEHE40_S-8_validation_Myers.pdf BHLHE40 (sc-101023) 20 BHLHE40_(NB100-1800) BHLHE40c BHLHE40 Rabbit polyclonal, maps to a region between residues 350 and the C-terminus (residue 412). Antibody Target: BHLHE40 This gene encodes a basic helix-loop-helix protein expressed in various tissues. Expression in the chondrocytes is responsive to the addition of Bt2cAMP. The encoded protein is believed to be involved in the control of cell differentiation. Novus NB100-1800 http://www.novusbio.com/DEC1-Antibody-_NB100-1800.html?rr=true Snyder GeneCard:BHLHE40 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BHLHE40 Human_-_:missing Mouse_-_:missing BHLHE40 (NB100-1800) N/A 21 BRCA1_(A300-000A) BRCA1 BRCA1 Rabbit polyclonal recognizing a region between residue 1800 and the C-terminus (residue 1863) of human Breast Cancer Gene 1. Antibody Target: BRCA1 Nuclear phosphoprotein that plays a role in maintaining genomic stability, and acts as a tumor suppressor. Associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. Plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Bethyl Labratories A300-000A http://www.bethyl.com/product/A300-000A/BRCA1_Antibody/ Snyder GeneCard:BRCA1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BRCA1 Human_-_:missing BRCA1 (A300-000A) 22 BRF1 BRF1 BRF1 Rabbit polyclonal - Anti-BRF antibody 128 was raised by immunising rabbits with synthetic peptide KISSKINYSVLRGLS (human BRF residues 533-547) coupled to keyhole limpet haemocyanin. Antibody Target: BRF1 'B-related factor 1', subunit of RNA polymerase III transcription initiation factor IIIB Donated by Dr. RJ White, The Beatson Institute for Cancer Research 128 http://www.beatson.gla.ac.uk/Regulation-of-Cancer-Cell-Proliferation-and-Growth/Robert-J-White-Gene-Transcription.html Struhl GeneCard:BRF1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BRF1 Human_-_:missing BRF1 (128) 23 BRF2 BRF2 BRF2 Antibody 4295 against Brf2 was raised by immunizing rabbits with keyhole limpet hemocyanin coupled to synthetic peptides VSRSQQRGLRRVRDLC and SDSEIEQYLRTPQEVR, corresponding to human Brf2 residues 66-80 and 385-400, respectively. Antibody Target: BRF2 Brf2 is a component of an alternate form of the RNA Polymerase III transcription factor TFIIIB. Donated by Dr. RJ White, The Beatson Institute for Cancer Research 4295 http://www.beatson.gla.ac.uk/Regulation-of-Cancer-Cell-Proliferation-and-Growth/Robert-J-White-Gene-Transcription.html Struhl GeneCard:BRF2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BRF2 Human_-_:missing BRF2 (4295) 24 Brg1 BRG1 BRG1 Brg-1 (G-7) is a mouse monoclonal antibody raised against amino acids 209-296 mapping near the N-terminus of Brg-1 of human origin. Antibody Target: BRG1 Brg1 (SMARCA4) is an ATPase subunit of the SWI/SNF chromatin-remodeling complex. Santa Cruz Biotech sc-17796 http://www.scbt.com/datasheet-17796-brg-1-g-7-antibody.html Snyder GeneCard:SMARCA4 http://www.genecards.org/cgi-bin/carddisp.pl?gene=SMARCA4 Human_-_BRG1(Immunoprecipitation,IP-Mass_spec):human_BRG1_validation_Snyder.pdf BRG1 (sc-17796) 25 BTF3_(SC-166093) BTF3SC166093 BTF3 Mouse monoclonal IgG, raised against amino acids 1-206 representing full length BTF3a of human origin. Antibody Target: BTF3 This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes. (provided by RefSeq) Santa Cruz Biotech sc-166093 http://www.scbt.com/datasheet-166093-btf3a-b-a-5-antibody.html Myers GeneCard:BTF3 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BTF3 Human_-_BTF3_(SC-166093):human_BTF3_SC-166093_validation_Myers.pdf BTF3 (sc-166093) G2209 26 c-Fos CFOS c-Fos Rabbit polyclonal to amino acids 210-335 mapping at the C-terminus of c-Fos of human origin. Antibody Target: c-Fos Heterodimer of Fos and Jun constitute transcription factor AP1. Proto-oncogene c-Jun is a leucine-zipper. Santa Cruz Biotech sc-7202 http://www.scbt.com/product.php?datasheet=7202 Snyder GeneCard:FOS http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOS Human_-_:missing c-Fos (sc-7202) 27 c-Jun CJUN c-Jun Rabbit polyclonal to amino acids 1-79 mapping at the N-terminus of c-Jun p39 of human origin. Antibody Target: c-Jun Heterodimer of Fos and Jun constitute transcription factor AP1. Proto-oncogene c-Jun is a leucine-zipper. Santa Cruz Biotech sc-1694 http://www.scbt.com/product.php?datasheet=1694 Snyder GeneCard:JUN http://www.genecards.org/cgi-bin/carddisp.pl?gene=JUN Human_-_c-Jun(Immunoprecipitation,Motif_Enrichment):human_c-Jun_validation_Snyder.pdf Mouse_-_:missing c-Jun (sc-1694) 28 c-Myb_(SC-7874) CMYB c-Myb Rabbit polyclonal IgG, Epitope corresponding to amino acids 500-640 mapping at the C-terminus of c-Myb of human origin. Antibody Target: c-Myb Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. Santa Cruz Biotech sc-7874 http://www.scbt.com/datasheet-7874-c-myb-h-141-antibody.html Snyder GeneCard:MYB http://www.genecards.org/cgi-bin/carddisp.pl?gene=MYB Mouse_-_:missing c-Myb (sc-7874) 29 c-Myc CMYC c-Myc rabbit polyclonal to amino acids 1-262 of c-Myc human origin. Antibody Target: c-Myc transcription factor; c-Myc-encoded proteins function in cell proliferation,differentiation and neoplastic disease Santa Cruz Biotech sc-764 http://www.scbt.com/product.php?datasheet=764 Iyer, Snyder GeneCard:MYC http://www.genecards.org/cgi-bin/carddisp.pl?gene=MYC Human_-_:missing Mouse_-_:missing c-Myc (sc-764) H0107 30 CCNT2 CCNT2 CCNT2 Goal polyclonal. Raised against an internal region of human CycT2a/b. Recommeded for detection of CycT2a/b of rat, mouse or human origin. Vendor recommeds it use for the folloiwng applications: WB, IF and ELISA. Antibody Target: CCNT2 CycT2 is one of three cyclins that can form a heterodimer with cyclin-dependent kinase 9 (CDK9). The heterodimer is known as positive elongation factor b (P-TEFb) and is responsible for the phosphophorylation of Ser2 of the heptad repeat in the C-terminal domain of RNA polymerase II as well as the negative elongation factors DSIF (hSpt4/hSpt5) and NELF. Phosphorylation of RNA polymerase II and the negative elongation factors by P-TEFb promotes elongation. CycT2 contains a leucine rich domain capable of binding to the C-terminal domain of RNA polymerase II. Santa Cruz Biotechnology sc-12419 http://www.scbt.com/datasheet-12419-cyclin-t2a-b-a-20-antibody.html Struhl GeneCard:CCNT2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CCNT2 Human_-_:missing CCNT2 (sc-12419) H2306 31 CDK9_(ab75898) CDK9AB75898 CDK9 Rabbit polyclonal, immunogen= multiple synthetic peptides corresponding to C-terminal and N-terminal domains of the protein coded by the human gene cdk9 (PITALRE). Antibody Target: CDK9 Cyclin dependent kinase 9 (CDK9) heterodimerizes with Cyclin T1 or Cyclin T2. The heterodimer is also known as positive elongation factor B (P-TEFb) and is responsible for the phosphorylation of Ser2 of the RNA polymerase II C-terminal Abcam ab75898 http://www.abcam.com/Cdk9-antibody-ab6544.html Struhl GeneCard:CDK9 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CDK9&search=cdk9 Human_-_CDK9_(ab75898)(Western_blot,ChIP):human_CDK9_ab75898_validation_Struhl.pdf CDK9 (ab75898) 32 CEBPB CEBPB CEBPB Rabbit polyclonal IgG. Antibody Target: CEBPB epitope mapping at the C-terminus of C/EBP-beta of rat origin Santa Cruz Biotech sc-150 http://www.scbt.com/datasheet-150-c-ebp-beta-c-19-antibody.html Snyder, Myers GeneCard:CEBPB http://www.genecards.org/cgi-bin/carddisp.pl?gene=CEBPB Human_-_CEPBbeta(Immunoprecipitation,Motif_Enrichment):human_CEBPbeta_validation_Snyder.pdf Mouse_-_:missing CEBPB (sc-150) I1010 (Myers) 33 CEBPB_(SC-150) CEBPBSC150 CEBPB Rabbit polyclonal IgG, epitope mapping at the C-terminus of CEBPB of rat origin. Antibody Target: CEBPB The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene (provided by RefSeq). Santa Cruz Biotech sc-150 http://www.scbt.com/datasheet-150-c-ebp-beta-c-19-antibody.html Myers GeneCard:CEBPB http://www.genecards.org/cgi-bin/carddisp.pl?gene=CEBPB Human_-_CEBPB_(SC-150)(Western_blot,IP-Mass_Spec):human_CEBPB_SC-150_validation_Myers.pdf CEBPB (sc-150) I1010 34 CEBPD_(SC-636) CEBPDSC636 CEBPD Rabbit polyclonal IgG, epitope mapping at the C-terminus of CEBPD of human origin. Antibody Target: CEBPD The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11 (provided by RefSeq). Santa Cruz Biotech sc-636 http://www.scbt.com/datasheet-636-c-ebp-delta-m-17-antibody.html Myers GeneCard:CEBPD http://www.genecards.org/cgi-bin/carddisp.pl?gene=CEBPD Human_-_CEBPD_(SC-636)(Western_blot,IP-Mass_Spec):human_CEBPD_SC-636_validation_Myers.pdf CEBPD (sc-636) C1010 35 CEBPZ CEBPZ CEBPZ Rabbit polyclonal, immunogen sequence= KDNASLKQLRWEAERDDWLHNRDAKSIIKKKKHFKKKRIKTTQKTKKQRK. Antibody Target: CEBPZ Stimulates transcription from the HSP70 promoter. Sigma-Aldrich SAB2100398 http://www.sigmaaldrich.com/catalog/ProductDetail.do?lang=en&N4=SAB2100398 Snyder GeneCard:CEBPZ http://www.genecards.org/cgi-bin/carddisp.pl?gene=CEBPZ Human_-_CEBPZ(Immunoprecipitation,IP-Mass_spec):human_CEBPZ_validation_Snyder.pdf CEBPZ (SAB2100398) QC8343 36 CHD1_(A301-218A) CHD1A301218A CHD1 Rabbit Polyclonal Antigen Affinity Purified, Unconjugated, Liquid. Antibody Target: CHD1 CHD1 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD1 has been shown to interact with the transcriptional corepressor NCoR and histone deacetylase 1 indicating a role in transcriptional regulation. CHD1 has also been shown to interact with the Paf1 complex and Rtf1 implicating an additional role in transcriptional elongation. Alternate names for CHD1 include chromodomain-helicase-DNA-binding protein 1, ATP-dependent helicase CHD1, and DKFZp686E2337. Bethyl Laboratories A301-218A http://www.bethyl.com/product/A301-218A Bernstein GeneCard:CHD1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CHD1 Human_-_CHD1_(A301-218A)(ChIP-String,ChIP-seq):human_CHD1_validation_Bernstein.pdf CHD1 (A301-218A) A301-218A-1 37 CHD1_(NB100-60411) CHD1NB10060411 CHD1 Rabbit polyclonal, The epitope recognized by this antibody maps to a region between residue 1660 and 1710 of human chromodomain helicase DNA binding protein 1 using the numbering given in entry NP_001261.2 (GeneID 1105). Antibody Target: CHD1 ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells Novus Biologicals NB100-60411 http://www.novusbio.com/CHD1-Antibody_NB100-60411.html Snyder GeneCard:CHD1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CHD1 Human_-_CHD1_(NB100-60411)(Immunoprecipitation,IP-Mass_spec):human_CHD1_NB100-60411_validation_Snyder.pdf CHD1 (NB100-60411) A1 38 CHD2_(AB68301) CHD2 CHD2 Rabbit polyclonal to CHD2 Synthetic peptide derived from within residues 1250 - 1350 of Human CHD2. Antibody Target: CHD2 CHD family of proteins are characterized by presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Abcam ab68301 http://www.abcam.com/CHD2-antibody-ab68301.html Snyder GeneCard:CHD2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CHD2 Human_-_:missing Mouse_-_:missing CHD2 (ab68301) 39 CREB1_(06-863) CREB106863 CREB1 Rabbit polyclonal, immunogen= KLH-conjugated, synthetic peptide (CSGAENQ QSGDAAVTEAENQQ) corresponding to a.a. 5-24 of human CREB. The immunizing sequence is identical in pig, shares 19 of 20 residues with mouse and bovine and 18 of 20 residues with rat. Antibody Target: CREB1 CREB is a basic leucine zipper transcription factor. CREB is activated by phosphorylation of Ser133 in response to a range of stimuli by including a number of transcription factors PKA, CAMK and MAPKs. CREB is ubiquitously expressed, but has been specifically implicated in the development in neurite outgrowth and neuronal differentiation. Millipore 06-863 http://www.millipore.com/catalogue/item/06-863 Struhl GeneCard:CREB1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CREB1 Human_-_CREB1_(06-863)(Western_blot,ChIP):human_CREB1_06-863_validation_Struhl.pdf CREB1 (06-863) 40 CREB1_(9198) CREB19198 CREB1 Rabbit monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser133 of human CREB. Antibody Target: CREB1 CREB is a basic leucine zipper transcription factor. CREB is activated by phosphorylation of Ser133 in response to a range of stimuli by including a number of transcription factors PKA, CAMK and MAPKs. CREB is ubiquitously expressed, but has been specifically implicated in the development in neurite outgrowth and neuronal differentiation. Cell Signaling 9198 http://www.cellsignal.com/pdf/9198.pdf Struhl GeneCard:CREB1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CREB1 Human_-_CREB1_(9188)_(Cell_Signaling_9198)(Western_blot,ChIP):human_CREB1_9198_validation_Struhl.pdf CREB1 (9198) 41 CREB1_(SC-240) CREB1SC240 CREB1 Mouse monoclonal IgG1; raised against amino acids 254-327 mapping within the DNA binding and dimerization domain of human CREB-1. Antibody Target: CREB1 This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. (provided by RefSeq) Santa Cruz Biotech sc-240 http://www.scbt.com/datasheet-240-creb-1-x-12-antibody.html Myers GeneCard:CREB1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CREB1 Human_-_CREB1_(SC-240)(Western_blot,IP-Mass_Spec):human_CREB1_SC-240_validation_Myers.pdf CREB1 (sc-240) C2306 42 CTCF CTCF CTCF rabbit polyclonal. Antibody Target: CTCF CTCF zinc finger transcription factor. A sequence specific DNA binding protein that functions as an insulator, blocking enhancer activity. It has also been suggested to block the spreading of chromatin structure in certain instances. Millipore 07-729 http://www.millipore.com/catalogue/item/07-729 Hardison GeneCard:CTCF http://www.genecards.org/cgi-bin/carddisp.pl?gene=CTCF Human_-_:missing Mouse_-_CTCF(Western_blot):mouse_CTCF_validation_Hardison.pdf CTCF (07-729) 1350637, DAM1472197 43 CTCF_(SC-15914) CTCFb CTCF Goat polyclonal, epitope mapping near the C-terminus of CTCF of human origin. Antibody Target: CTCF Transcriptional regulator with 11 highly conserved zinc finger domains. Depending on context, can bind a histone acetyltransferase (HAT)-containing complex and function as transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as transcriptional repressor. Involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. Preferentially interacts with unmethylated DNA, preventing spreading of CpG methylation. Can dimerize, mediating long-range chromatin looping. When bound to chromatin, provides an anchor point for nucleosomes positioning. Involved in sister chromatid cohesion. Associates with both centromeres and chromosomal arms during metaphase and required for cohesin localization to CTCF sites. Santa Cruz Biotech sc-15914 http://www.scbt.com/datasheet-15914-ctcf-c-20-antibody.html Snyder GeneCard:CTCF http://www.genecards.org/cgi-bin/carddisp.pl?gene=CTCF Human_-_:missing Mouse_-_:missing CTCF (sc-15914) 44 CTCF_(SC-5916) CTCFc CTCF Goat polyclonal IgG, epitope mapping at the N-terminus of CTCF of human origin. Antibody Target: CTCF This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. (provided by RefSeq) Santa Cruz Biotech sc-5916 http://www.scbt.com/datasheet-5916-ctcf-n-17-antibody.html Myers GeneCard:CTCF http://www.genecards.org/cgi-bin/carddisp.pl?gene=CTCF Human_-_:missing CTCF (sc-5916) K0902 45 CTCFL_(SC-98982) CTCFL CTCFL Rabbit polyclonal IgG, epitope corresponding to amino acids 91-210 mapping within an internal region of BORIS(CTCFL) of human origin. Antibody Target: CTCFL CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. (provided by RefSeq) Santa Cruz Biotech sc-98982 http://www.scbt.com/datasheet-98982-boris-h-120-antibody.html Myers GeneCard:CTCFL http://www.genecards.org/cgi-bin/carddisp.pl?gene=CTCFL Human_-_:missing CTCFL (sc-98982) E0109 46 CtBP1 CTBP1 CtBP1 mouse monoclonal. Antibody Target: CtBP1 C-terminal binding protein 1 BD Biosciences 612042 http://www.bdbiosciences.com/ptProduct.jsp?prodId=229303 Farnham GeneCard:CTBP1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CTBP1 CtBP1 (612042) 47 CtBP2 CTBP2 CtBP2 mouse monoclonal. Antibody Target: CtBP2 C-terminal binding protein 2 BD Biosciences 612044 http://www.bdbiosciences.com/ptProduct.jsp?prodId=229326 Farnham GeneCard:CTBP2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CTBP2 Human_-_CtBP2(Western_blot,siRna):human_CtBP2_validation_Farnham.pdf CtBP2 (612044) 48 CycT1_(sc-10750) CYCT1SC10750 CycT1 Rabbit polyclonal, epitope corresponding to amino acids 261-505 mapping to an internal region of cyclin T1 of human origin. Antibody Target: CycT1 Cyclin T1 is a cyclin that forms heterodimers with the cyclin dependent kinase CDK9. CDK9 is responsible for phosphorylating Ser2 of the heptad repeat of the C-terminal domain of the large subunit of RNA polymerase II, and negative elongation factors NELF and DSIF. Cyclin T1 makes contacts with RNAPII and nascent mRNA and as such recruits CDK9 to facilitate release of stalled RNAPII and productive elongation. Santa Cruz Biotech sc-10750 http://www.scbt.com/datasheet-10750-cyclin-t1-h-245-antibody.html Struhl GeneCard:CCNT1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CCNT1 Human_-_CycT1_(sc-10750)(Western_blot,Immunoprecipitation):human_CycT1_sc-10750_validation_Struhl.pdf CycT1 (sc-10750) 49 E2F1 E2F1 E2F1 E2F1(KH20 and KH95) is a mouse monoclonal antibody. The epitope for KH20 has been mapped to amino acids 1-89; KH95 to amino acids 342-386. Recommended for detection of E2F1 of H and Xn origin by WB and IP. Antibody Target: E2F1 E2F1, the original member of the E2F family of transcription factors, was identified as a cellular protein with DNA binding activity associated with the adenovirus E2 gene promoter. E2F1 is cell cycle regulated with very low levels in early G1, then increasing levels as cells move from G1 to S, and highest levels of protein at the G1/S boundary, which is consistent with its role in S-phase entry. Millipore 05-379 http://www.millipore.com/catalogue/item/05-379# Farnham GeneCard:E2F1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=E2F1 Human_-_E2F1(Immunoprecipitation-Western_blot,ChIP):human_E2F1_HA-E2F1_validation_Farnham.pdf E2F1 (05-379) 50 E2F4 E2F4 E2F4 rabbit polyclonal. Antibody Target: E2F4 mapping at the C-terminus of E2F4 of human origin Santa Cruz Biotech sc-866 http://www.scbt.com/datasheet-866-e2f-4-c-20-antibody.html Farnham GeneCard:E2F4 http://www.genecards.org/cgi-bin/carddisp.pl?gene=E2F4 Human_-_E2F4(Immunoprecipitation-Western_blot,ChIP):human_E2F4_validation_Farnham.pdf Mouse_-_:missing E2F4 (sc-866) 51 E2F6 E2F6 E2F6 Rabbit polyclonal IgG, epitope corresponding to a.a. 232-281 mapping at the C-terminus of E2F-6 of human origin. Antibody Target: E2F6 This gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in control of the cell cycle and of the action of tumor suppressor proteins. They are also a target of the transforming proteins of small DNA tumor viruses. Many E2F proteins contain several evolutionarily conserved domains: a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. The encoded protein of this gene is atypical because it lacks the transactivation and tumor suppressor protein association domains. It contains a modular suppression domain and is an inhibitor of E2F-dependent transcription. The protein is part of a multimeric protein complex that contains a histone methyltransferase and the transcription factors Mga and Max. Multiple transcript variants have been reported for this gene, but it has not been clearly demonstrated that they encode valid isoforms (RefSeq). Santa Cruz Biotech sc-22823 http://www.scbt.com/datasheet-22823-e2f-6-h-50-antibody.html Farnham, Myers GeneCard:E2F6 http://www.genecards.org/cgi-bin/carddisp.pl?gene=E2F6 Human_-_E2F6(Western_blot,siRNA-ChIP):human_E2F6_validation_Farnham.pdf Human_-_E2F6_(Myers)(Western_blot,IP-MassSpec):human_E2F6_validation_Myers.pdf E2F6 (sc-22823) D1206 (Myers) 52 EBF1_(SC-137065) EBF1 EBF1 Mouse monoclonal IgG, raised against a.a. 1-300 mapping at the N-terminus of EBF of human origin. Antibody Target: EBF1 Early B-cell factor 1. Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity). Santa Cruz Biotech sc-137065 http://www.scbt.com/datasheet-137065-ebf-c-8-antibody.html Myers EBF1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=EBF1 Human_-_EBF1_(SC-137065)(Immunoprecipitation-Western_blotMassSpec):human_EBF1_SC-137065_validation_Myers.pdf EBF1 (sc-137065) J0505 53 eGFP-BACH1 BACH1 eGFP-BACH1 Goat polyclonal raised against e-GFP tagged transcription factor BACH1. Antibody Target: eGFP-BACH1 This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-BACH1 http://www.igsb.org/labs/kevin-white/ White GeneCard:BACH1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=BACH1 Human_-_:missing BACH1 (eGFP-BACH1) 1 54 eGFP-CCNE1 CCNE1 eGFP-CCNE1 Goat polyclonal raised against e-GFP tagged transcription factor CCNE1. Antibody Target: eGFP-CCNE1 The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-CCNE1 http://www.igsb.org/labs/kevin-white/ White GeneCard:CCNE1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=CCNE1 Human_-_:missing CCNE1 (eGFP-CCNE1) 1 55 eGFP-CDKN1B CDKN1B eGFP-CDKN1B Goat polyclonal raised against e-GFP tagged transcription factor CDKN1B. Antibody Target: eGFP-CDKN1B This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1 (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-CDKN1B http://www.igsb.org/labs/kevin-white/ White GeneCard:CDKN1B http://www.genecards.org/cgi-bin/carddisp.pl?gene=CDKN1B Human_-_:missing CDKN1B (eGFP-CDKN1B) 1 56 eGFP-E2F1 E2F1 eGFP-E2F1 Goat polyclonal raised against e-GFP tagged transcription factor E2F1. Antibody Target: eGFP-E2F1 The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-E2F1 http://www.igsb.org/labs/kevin-white/ White GeneCard:E2F1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=E2F1 Human_-_:missing E2F1 (eGFP-E2F1) 1 57 eGFP-EKLF1 EKLF1 eGFP-EKLF1 Goat polyclonal raised against e-GFP tagged transcription factor EKLF1. Antibody Target: eGFP-EKLF1 This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-EKLF1 http://www.igsb.org/labs/kevin-white/ White GeneCard:EKLF1 missing Human_-_:missing EKLF1 (eGFP-EKLF1) 1 58 eGFP-ELF1 ELF1 eGFP-ELF1 Goat polyclonal raised against e-GFP tagged transcription factor ELF1. Antibody Target: eGFP-ELF1 This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-ELF1 http://www.igsb.org/labs/kevin-white/ White GeneCard:ELF1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ELF1 Human_-_:missing ELF1 (eGFP-ELF1) 1 59 eGFP-ESR ESR eGFP-ESR Goat polyclonal raised against e-GFP tagged transcription factor ESRA. Antibody Target: eGFP-ESR This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-ESR http://www.igsb.org/labs/kevin-white/ White GeneCard:ESR http://www.genecards.org/cgi-bin/carddisp.pl?gene=ESR1 Human_-_:missing ESR (eGFP-ESR) 1 60 eGFP-FOS FOSe FOS Goat polyclonal. Antibody Target: FOS Fos Kevin White Missing http://www.genes.uchicago.edu/white.html White GeneCard:FOS http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOS Human_-_eGFP-FOS:human_validation_White.pdf FOS (eGFP-FOS) N/A 61 eGFP-GATA2 GATA2e GATA2 Goat polyclonal. Antibody Target: GATA2 GATA2 Kevin White Missing http://www.genes.uchicago.edu/white.html White GeneCard:GATA2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=GATA2 Human_-_eGFP-GATA2:human_validation_White.pdf GATA2 (eGFP-GATA2) N/A 62 eGFP-HDAC8 HDAC8e HDAC8 Goat polyclonal. Antibody Target: HDAC8 HDAC8 Kevin White Missing http://www.genes.uchicago.edu/white.html White GeneCard:HDAC8 http://www.genecards.org/cgi-bin/carddisp.pl?gene=HDAC8 Human_-_eGFP-HDAC8:human_validation_White.pdf HDAC8 (eGFP-HDAC8) N/A 63 eGFP-HMGB1 HMGB1 eGFP-HMGB1 Goat polyclonal raised against e-GFP tagged transcription factor HMGB1. Antibody Target: eGFP-HMGB1 DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-HMGB1 http://www.igsb.org/labs/kevin-white/ White GeneCard:HMGB1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=HMGB1 Human_-_:missing HMGB1 (eGFP-HMGB1) 1 64 eGFP-ILF2 ILF2 eGFP-ILF2 Goat polyclonal raised against e-GFP tagged transcription factor ILF2. Antibody Target: eGFP-ILF2 Nuclear factor of activated T-cells (NFAT) is a transcription factor required for T-cell expression of the interleukin 2 gene. NFAT binds to a sequence in the interleukin 2 gene enhancer known as the antigen receptor response element 2. In addition, NFAT can bind RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-ILF2 http://www.igsb.org/labs/kevin-white/ White GeneCard:ILF2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ILF2 Human_-_:missing ILF2 (eGFP-ILF2) 1 65 eGFP-JunB JUNBe JunB Goat polyclonal. Antibody Target: JunB JunB Kevin White Missing http://www.genes.uchicago.edu/white.html White GeneCard:JUNB http://www.genecards.org/cgi-bin/carddisp.pl?gene=JUNB Human_-_eGFP-JunB:human_validation_White.pdf JunB (eGFP-JunB) N/A 66 eGFP-JunD JUNDe JunD Goat polyclonal. Antibody Target: JunD JunD Kevin White Missing http://www.genes.uchicago.edu/white.html White GeneCard:JUND http://www.genecards.org/cgi-bin/carddisp.pl?gene=JUND Human_-_eGFP-JunD:human_validation_White.pdf JunD (eGFP-JunD) N/A 67 eGFP-MLL5 MLL5 eGFP-MLL5 Goat polyclonal raised against e-GFP tagged transcription factor MLL5. Antibody Target: eGFP-MLL5 This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-MLL5 http://www.igsb.org/labs/kevin-white/ White GeneCard:MLL5 http://www.genecards.org/cgi-bin/carddisp.pl?gene=MLL5 Human_-_:missing MLL5 (eGFP-MLL5) 1 68 eGFP-NCOR1 NCOR1 eGFP-NCOR1 Goat polyclonal raised against e-GFP tagged transcription factor NCOR1. Antibody Target: eGFP-NCOR1 This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17 (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-NCOR1 http://www.igsb.org/labs/kevin-white/ White GeneCard:NCOR1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=NCOR1 Human_-_:missing NCOR1 (eGFP-NCOR1) 1 69 eGFP-NF90 NF90 eGFP-NF90 Goat polyclonal raised against e-GFP tagged transcription factor NF90. Antibody Target: eGFP-NF90 NF90 (nuclear factor of activated T cells 90 kDa), also known as NFAR is a ubiquitously expressed nuclear protein that exists in a heterodimer with NF45. (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-NF90 http://www.igsb.org/labs/kevin-white/ White GeneCard:ILF3 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ILF3 Human_-_:missing NF90 (eGFP-NF90) 1 70 eGFP-NR4A1 NR4A1e NR4A1 Goat polyclonal. Antibody Target: NR4A1 NR4A1 Kevin White Missing http://www.genes.uchicago.edu/white.html White GeneCard:NR4A1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=Nr4a1 Human_-_eGFP-NR4A1:human_validation_White.pdf NR4A1 (eGFP-NR4A1) N/A 71 eGFP-SMARCA1 SMARCA1 eGFP-SMARCA1 Goat polyclonal raised against e-GFP tagged transcription factor SMARCA1. Antibody Target: eGFP-SMARCA1 This gene encodes a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-SMARCA1 http://www.igsb.org/labs/kevin-white/ White GeneCard:SMARCA1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=SMARCA1 Human_-_:missing SMARCA1 (eGFP-SMARCA1) 1 72 eGFP-SMARCA2 SMARCA2 eGFP-SMARCA2 Goat polyclonal raised against e-GFP tagged transcription factor SMARCA2. Antibody Target: eGFP-SMARCA2 The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-SMARCA2 http://www.igsb.org/labs/kevin-white/ White GeneCard:SMARCA2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=SMARCA2 Human_-_:missing SMARCA2 (eGFP-SMARCA2) 1 73 eGFP-STAT1 STAT1 eGFP-STAT1 Goat polyclonal raised against e-GFP tagged transcription factor STAT1. Antibody Target: eGFP-STAT1 The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo-or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6 (provided by RefSeq) Kevin White Lab, University of Chicago eGFP-STAT1 http://www.igsb.org/labs/kevin-white/ White GeneCard:STAT1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=STAT1 Human_-_:missing STAT1 (eGFP-STAT1) 1 74 ELF1_(SC-631) ELF1 ELF1 Rabbit polyclonal IgG, epitope mapping at the C-terminus of Elf-1 of human origin. Antibody Target: ELF1 This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants. (provided by RefSeq) Santa Cruz Biotech sc-631 http://www.scbt.com/datasheet-631-elf-1-c-20-antibody.html Myers GeneCard:ELF1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ELF1 Human_-_ELF1_(SC-631)(Western_blot,IP-MassSpec):human_ELF1_SC-631_validation_Myers.pdf ELF1 (sc-631) L2707 75 ELK4 ELK4 ELK4 Rabbit polyclonal IgG. Antibody Target: ELK4 This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. (provided by RefSeq) Santa Cruz Biotech sc-13030 http://datasheets.scbt.com/sc-13030.pdf Farnham GeneCard:ELK4 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ELK4 Human_-_ELK4(Western_blot,ChIP-seq):human_ELK4_validation_Farnham.pdf ELK4 (sc-13030) 76 ERalpha_a ERAA ERalpha_a Rabbit affinity purified polyclonal antibody. Epitope is the C-terminus of human estrogen receptor alpha (ESR1). Recommended for detection of estrogen receptor of m, r and h origin by WB, IP, IF, IHC(P) and ELISA. Antibody Target: ERalpha_a This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5-prime UTRs and use different promoters. (provided by RefSeq) Santa Cruz Biotech sc-543 http://www.scbt.com/datasheet-543-eralpha-hc-20-antibody.html Ruan GeneCard:ESR1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ESR1&search=ESR1 Human_-_ERalpha_a(Immunoprecipitation-Western_blot,MassSpect):human_ERalpha_a_validation_Myers.pdf ERalpha_a (sc-543) C2510, G1509 77 ERalpha_b ERAB ERalpha_b Monoclonal antibody raised in mouse against the NH2 terminus of the human ER (estrogen receptor alpha), using a KLH-conjugated synthetic peptide (Q19-K32). Antibody Target: ERalpha_b This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5-prime UTRs and use different promoters. (provided by RefSeq) Diagenode MAb-009-050 http://www.diagenode.com/en/catalog/antibodies-3/nuclear-receptor-30/product/er-alpha-monoclonal-antibody-185 Ruan GeneCard:ESR1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ESR1 ERalpha_b (MAb-009-050) 78 Egr-1 EGR1 EGR1 Rabbit polyclonal, EGR-1 (588). Antibody Target: EGR1 Egr-1, Egr-2, Egr-3 and Egr-4 are nuclear transcription factors belonging to the Egr C2H2-type zinc-finger protein family and containing three C2H2-type zinc fingers. As immediate early proteins, Egr transcription factors are rapidly induced by diverse extracellular stimuli. Egr proteins are subject to tight differential control through diverse mechanisms at several levels of regulation including transcriptional, translational and post-translational (including glyco- sylation, phosphorylation and redox) mechanisms and protein-protein inter- action. Egr-1 binds to the DNA sequence 5'-CGCCCCCGC-3' (EGR-site), there- by activating transcription of target genes whose products are required for mitogenisis and differentiation. Egr-2 binds specific DNA sites located in the promoter region of HoxA4. Egr-2 defects cause congenital hypomyelination neuropathy (also designated Charcot-Marie-tooth disease) and Dejerine- Sottas neuropathology (also designated hereditary motor and sensory neuro- pathy III. Egr-3 is involved in muscle spindle development and is expressed in T cells 20 minutes following activation. EGR-4 binds to the EGR consensus motif GCGTGGGCG, functions as a transcriptional repressor, and displays autoregulatory activities, downregulating its on gene promoter in a dose dependent manner. Santa Cruz Biotech sc-110 http://www.scbt.com/product.php?datasheet=110 Farnham GeneCard:EGR1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=EGR1 Human_-_Egr-1(Immunoblot):human_Egr-1_588_validation_Myers.pdf EGR1 (sc-110) 79 ERRA ERRA ERRA Rabbit polyclonal IgG, epitope mapping at the C-terminus of Ets-1 of human origin. Antibody Target: ERRA epitope corresponding to amino acids 81-160 mapping near the N-terminus of ERRalpha of human origin Santa Cruz Biotech sc-66882 http://www.scbt.com/datasheet-66882-erralpha-h-80-antibody.html Snyder GeneCard:ESRRA http://www.genecards.org/cgi-bin/carddisp.pl?gene=ESRRA Human_-_ERRA(Western_blot,Motif_Enrichment):human_ERRA_validation_Snyder.pdf ERRA (sc-66882) 80 ETS1 ETS1 ETS1 Rabbit polyclonal IgG. Antibody Target: ETS1 ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis Santa Cruz Biotech sc-350 http://www.scbt.com/datasheet-350-ets-1-c-20-antibody.html Myers GeneCard:ETS1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=ETS1 Human_-_ETS1(Immunoprecipitation-Western_blot,MassSpec):human_ETS1_validation_Myers.pdf Mouse_-_:missing ETS1 (sc-350) A1608 81 EZH2_(39875) EZH239875 EZH2 This EZH2 antibody was raised against a recombinant protein corresponding to amino acids 353-451 of human EZH2. Antibody Target: EZH2 EZH2 (Enhancer of Zeste homolog 2, also designated Enx1 and SETDB1) is a human homolog of the Drosophila Polycomb-group protein Enhancer of Zeste protein. It contains a SET domain that catalyzes the methylation of histone H3 at lysine 27 (Histone H3 Lys27 monomethylated, dimethylated and trimethylated). Polycomb-group proteins repress gene expression by binding to chromatin and locally altering chromatin structure. EZH2, BMI-1 and Suz12 are present in the PRC2 and PRC3 protein complexes that function as mediators of epigenetic transcriptional silencing. EZH2 associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Deregulation of EZH2 is linked to a variety of cancers. Active Motif 39875 http://www.activemotif.com/catalog/details/39875/ezh2-antibody-mab-clone-ac22 Bernstein GeneCard:EZH2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=EZH2 Human_-_EZH2_(39875)(ChIP-String,ChIP-seq):human_EZH2_validation_Bernstein.pdf EZH2 (39875) 27210001 82 FOSL1_(SC-183) FOSL1 FOSL1 Rabbit polyclonal IgG, epitope mapping at the N-terminus of FOSL1 of human origin. Antibody Target: FOSL1 The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. (provided by RefSeq) Santa Cruz Biotech sc-183 http://www.scbt.com/datasheet-183-fra-1-n-17-antibody.html Myers GeneCard:FOSL1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOSL1 Human_-_FOSL1_(SC-183)(Western_blot,IP-MassSpec):human_FOSL1-SC183_validation_Myers.pdf FOSL1 (sc-183) I0809 83 FOSL1_(sc-605) FOSL1SC605 FOSL1 Rabbit polyclonal antibody raised against the N-terminus of FOSL1 of rat origin. Antibody Target: FOSL1 The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. (provided by RefSeq) Santa Cruz Biotech sc-605 http://www.scbt.com/datasheet-605-fra-1-r-20-antibody.html Wold Genecard:FOSL1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOSL1 Human_-_FOSL1_(sc-605): Mouse_-_:missing FOSL1 (sc-605) G0109 84 FOSL2 FOSL2 FOSL2 Fra-2(Q-20) is an affinity purified rabbit polyclonal raised against the N-terminus of Fra-2 of human origin. Recommended for detection of Fra-2 of m, r, h and chicken origin by WB, IP, IF, IHC(P) and ELISA. Antibody Target: FOSL2 The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Santa Cruz Biotech sc-604 http://www.scbt.com/datasheet-604-fra-2-q-20-antibody.html Myers GeneCard:FOSL2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOSL2 Human_-_FOSL2(Immunoblot):human_FOSL2_Q-20_validation_Myers.pdf FOSL2 (sc-604) 85 FOXA1_(SC-6553) FOXA1b FOXA1 Goat polyclonal IgG, epitope mapping at the C-terminus of FOXA1 of human origin. Antibody Target: FOXA1 This gene encodes a member of the forehead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver (RefSeq). Santa Cruz Biotech sc-6553 http://www.scbt.com/datasheet-6553-hnf-3alpha-beta-c-20-antibody.html Myers GeneCard:FOXA1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOXA1 Human_-_FOXA1(Immunoprecipitation-Western_blot,MassSpec):human_FOXA1_SC-6553_validation_Myers.pdf FOXA1 (sc-6553) 86 FOXA1_(SC-101058) FOXA1 FOXA1 Mouse monoclonal IgG, raised against recombinant HNF-3a of human origin. Antibody Target: FOXA1 This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. (provided by RefSeq) Santa Cruz Biotech sc-101058 http://www.scbt.com/datasheet-101058-hnf-3alpha-q-6-antibody.html Myers GeneCard:FOXA1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOXA1 Human_-_FOXA1_(SC-101058)(Immunoprecipitation-Western_blot,MassSpec):human_FOXA1_SC-101058_validation_Myers.pdf FOXA1 (sc-101058) A2706 87 FOXA2_(SC-6554) FOXA2 FOXA2 Goat polyclonal IgG, epitope mapping at the N-terminus of FOXA2 of human origin. Antibody Target: FOXA2 The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. (provided by RefSeq) Santa Cruz Biotech sc-6554 http://www.scbt.com/datasheet-6554-hnf-3beta-m-20-antibody.html Myers GeneCard:FOXA2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOXA2 Human_-_:missing FOXA2 (sc-6554) L1409 88 FOXM1_(SC-502) FOXM1SC502 FOXM1 Rabbit polyclonal IgG, epitope mapping at the C-terminus of FOXM1 of human origin. Antibody Target: FOXM1 The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2011) Santa Cruz Biotech sc-502 http://www.scbt.com/datasheet-502-foxm1-c-20-antibody.html Myers GeneCard:FOXM1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOXM1 Human_-_FOXM1_(sc-502)(Western_blot,ChIP):human_FOXM1_sc-502_validation_Myers.pdf FOXM1 (sc-502) C1909 89 FOXP2 FOXP2 FOXP2 Rabbit polyclonal, raised against C-terminal 127 amino acids of FOXP2 of human origin. Antibody Target: FOXP2 This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. Transcriptional repressor, involved in the development of speech Abcam ab16046 http://www.abcam.com/index.html?datasheet=16046 Myers GeneCard:FOXP2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=FOXP2 Human_-_FOXP2(Western_blot,siRNA):human_FOXP2_validation_Myers.pdf FOXP2 (ab16046) AB-2B 90 GABP GABP GABP Mouse monoclonal, GABPa(G-1), IgG1. Antibody Target: GABP The transcription factor GA-binding protein (GABP) is composed of two subunits, alpha and beta. Alpha binds to a specific DNA sequence. Santa Cruz Biotech sc-28312 http://www.scbt.com/product.php?datasheet=28312 Myers GeneCard:GABPB1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=GABPB1 Human_-_GABP(Immunoprecipitation-Western_blot,MassSpec):human_GABP_validation_Myers.pdf GABP (sc-28312) F1804 91 GATA-1 GATA1 GATA1 Anti-GATA-1 rabbit polyclonal antibody was generated by using a purified GST fusion to amino acids 1-89 of mouse GATA-1. Antibody Target: GATA1 GATA-1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG} within regulatory regions of globin genes and of other genes expressed in erythroid cells. Donated by Dr. E.H. Bresnick, UW Madison GATA-1 http://stemcells.wisc.edu/faculty/bresnick.html Farnham GeneCard:GATA1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=GATA1 Human_-_GATA-1_(Western_blot,ChIP):human_GATA-1_validation_Farnham.pdf Mouse_-_:missing GATA1 92 GATA1_(SC-265) GATA1a GATA1 rat monoclonal antibody raised against mouse recombinant GATA1; recommended for detection of GATA1 of mouse, rat and human origin. Antibody Target: GATA1 GATA1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. Santa Cruz Biotech sc-265 http://www.scbt.com/datasheet-265-gata-1-n6-antibody.html Hardison GeneCard:Gata1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=Gata1 Mouse_-_GATA1(Western_blot):mouse_GATA1_validation_Hardison.pdf GATA1 (sc-265) 93 GATA1_(SC-266) GATA1b GATA1 Rat monoclonal raised against bacterially expressed murine GATA-1. Antibody Target: GATA1 GATA1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. Santa Cruz Biotech sc-266 http://www.scbt.com/datasheet-266-gata-1-n1-antibody.html Snyder GeneCard:Gata1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=GATA1 Mouse_-_GATA1(Immunoblot):mouse_GATA1-SC266_validation_Snyder.pdf GATA1 (sc-266) 94 GATA-2 GATA2 GATA2 Rabbit polyclonal. Antibody Target: GATA2 GATA binding protein 2 Donated by Dr. E.H. Bresnick, UW Madison GATA-2 http://molpharm.wisc.edu/people/faculty/bresnick/bresnick.html Farnham GeneCard:GATA2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=GATA2 Human_-_GATA-2(Western_blot,siRNA):human_GATA-2_validation_Farnham.pdf GATA2 95 GATA2_(SC-267) GATA2b GATA2 Mouse monoclonal IgG. Antibody Target: GATA2 This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded program plays an essential role in regulation transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages (RefSeq). Santa Cruz Biotech sc-267 http://www.scbt.com/datasheet-267-gata-2-cg2-96-antibody.html Myers GeneCard:GATA2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=GATA2 Human_-_GATA2_(SC-267)(Immunoprecipitation-Western_blot,MassSpec):human_GATA2_SC-267_validation_Myers.pdf GATA2 (sc-267) E2708 96 GATA2_(SC-9008) GATA2SC9008 GATA2 Rabbit polyclonal antibody raised against amino acids 120-235 of GATA-2 of human origin. Antibody Target: GATA2 The GATA family of transcription factors share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA1 is erythroid-specific and is essential for normal erythropeisis. By comparison, GATA2 is expressed at high levels in hematopoeitic progenitors, including early erythroid cells, but is strong repressed during erythroblast differentiaion. Santa Cruz Biotech sc-9008 http://www.scbt.com/datasheet-9008-gata-2-h-116-antibody.html Hardison GeneCard: GATA2 http://www.genecards.org/cgi-bin/carddisp.pl?gene=GATA2 Human_-_GATA2_(SC-9008)(Western_blot):human_GATA2_SC-9008_validation_Hardison.pdf Mouse_-_:missing GATA2 (sc-9008) J2108 97 GATA3_(SC-268) GATA3 GATA3 Mouse monoclonal IgG raised against human recombinant GATA-3. Antibody Target: GATA3 This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is a n important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (provided by RefSeq). Santa Cruz Biotech sc-268 http://www.scbt.com/datasheet-268-gata-3-hg3-31-antibody.html Farnham GeneCard:GATA3 http://www.genecards.org/cgi-bin/carddisp.pl?gene=GATA3 Human_-_GATA3_SC-268(Western_blot,ChIP-seq):human_GATA3_SC-268_validation_Farnham.pdf GATA3 (sc-268) A2610 98 GATA3_(SC-269) GATA3SC269 GATA3 Mouse monoclonal IgG raised against human recombinant GATA-3 (amino acids 1-264). Antibody Target: GATA3 This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is a n important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (provided by RefSeq) Santa Cruz Biotech sc-269 http://www.scbt.com/datasheet-269-gata-3-hg3-35-antibody.html Farnham Genecard:GATA3 http://www.genecards.org/cgi-bin/carddisp.pl?gene=GATA3 Human_-_GATA3_SC-269_(siRNA,ChIP):human_GATA3_SC-269_validation_Farnham.pdf GATA3 (sc-269) A1404 99 GCN5 GCN5 GCN5 Rabbit polyclonal anti-GCN5 antibody (2676), Immunogen : synthetic peptide coupled to Ovalbumin (sequence-MAEPSQAPTPAPAAQPRPLC). Antibody Target: GCN5 KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. Acetylation of histones gives a specific tag for epigenetic transcription activation. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the SAGA and ATAC complexes, complexes with histone acetyltransferase activities on histones H3 and H4 Laszlo Tora Missing http://www.igbmc.fr/Tora Struhl GeneCard:KAT2A http://www.genecards.org/cgi-bin/carddisp.pl?gene=KAT2A&search=gcn5 Human_-_:missing GCN5 100 GR GR GR Rabbit Polyclonal. Antibody Target: GR Glucocorticoid Receptor Santa Cruz Biotech sc-1003 http://www.scbt.com/product.php?datasheet=1003 Myers GeneCard:NR3C1 http://www.genecards.org/cgi-bin/carddisp.pl?gene=NR3C1 Human_-_GR(Immunoblot):human_GR_M-20_validation_Myers.pdf GR (sc-1003) A2508, E1908