# $Id: OntologyTerm.pm 16123 2009-09-17 12:57:27Z cjfields $ # # BioPerl module for Bio::Annotation::OntologyTerm # # Please direct questions and support issues to # # Cared for by Hilmar Lapp # # Copyright Hilmar Lapp # # You may distribute this module under the same terms as perl itself # # (c) Hilmar Lapp, hlapp at gmx.net, 2002. # (c) GNF, Genomics Institute of the Novartis Research Foundation, 2002. # # You may distribute this module under the same terms as perl itself. # Refer to the Perl Artistic License (see the license accompanying this # software package, or see http://www.perl.com/language/misc/Artistic.html) # for the terms under which you may use, modify, and redistribute this module. # # THIS PACKAGE IS PROVIDED "AS IS" AND WITHOUT ANY EXPRESS OR IMPLIED # WARRANTIES, INCLUDING, WITHOUT LIMITATION, THE IMPLIED WARRANTIES OF # MERCHANTIBILITY AND FITNESS FOR A PARTICULAR PURPOSE. # # POD documentation - main docs before the code =head1 NAME Bio::Annotation::OntologyTerm - An ontology term adapted to AnnotationI =head1 SYNOPSIS use Bio::Annotation::OntologyTerm; use Bio::Annotation::Collection; use Bio::Ontology::Term; my $coll = Bio::Annotation::Collection->new(); # this also implements a tag/value pair, where tag _and_ value are treated # as ontology terms my $annterm = Bio::Annotation::OntologyTerm->new(-label => 'ABC1', -tagname => 'Gene Name'); # ontology terms can be added directly - they implicitly have a tag $coll->add_Annotation($annterm); # implementation is by composition - you can get/set the term object # e.g. my $term = $annterm->term(); # term is-a Bio::Ontology::TermI print "ontology term ",$term->name()," (ID ",$term->identifier(), "), ontology ",$term->ontology()->name(),"\n"; $term = Bio::Ontology::Term->new(-name => 'ABC2', -ontology => 'Gene Name'); $annterm->term($term); =head1 DESCRIPTION Ontology term annotation object =head1 FEEDBACK =head2 Mailing Lists User feedback is an integral part of the evolution of this and other Bioperl modules. Send your comments and suggestions preferably to one of the Bioperl mailing lists. Your participation is much appreciated. bioperl-l@bioperl.org - General discussion http://bioperl.org/wiki/Mailing_lists - About the mailing lists =head2 Support Please direct usage questions or support issues to the mailing list: I rather than to the module maintainer directly. Many experienced and reponsive experts will be able look at the problem and quickly address it. Please include a thorough description of the problem with code and data examples if at all possible. =head2 Reporting Bugs Report bugs to the Bioperl bug tracking system to help us keep track the bugs and their resolution. Bug reports can be submitted via the web: http://bugzilla.open-bio.org/ =head1 AUTHOR - Hilmar Lapp Email hlapp at gmx.net =head1 APPENDIX The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _ =cut # Let the code begin... package Bio::Annotation::OntologyTerm; use strict; # Object preamble - inherits from Bio::Root::Root use Bio::Ontology::Term; use base qw(Bio::Root::Root Bio::AnnotationI Bio::Ontology::TermI); =head2 new Title : new Usage : my $sv = Bio::Annotation::OntologyTerm->new(); Function: Instantiate a new OntologyTerm object Returns : Bio::Annotation::OntologyTerm object Args : -term => $term to initialize the term data field [optional] Most named arguments that Bio::Ontology::Term accepts will work here too. -label is a synonym for -name, -tagname is a synonym for -ontology. =cut sub new{ my ($class,@args) = @_; my $self = $class->SUPER::new(@args); my ($term,$name,$label,$identifier,$definition,$ont,$tag) = $self->_rearrange([qw(TERM NAME LABEL IDENTIFIER DEFINITION ONTOLOGY TAGNAME)], @args); if($term) { $self->term($term); } else { $self->name($name || $label) if $name || $label; $self->identifier($identifier) if $identifier; $self->definition($definition) if $definition; } $self->ontology($ont || $tag) if $ont || $tag; return $self; } =head1 AnnotationI implementing functions =cut =head2 as_text Title : as_text Usage : my $text = $obj->as_text Function: Returns a textual representation of the annotation that this object holds. Presently, it is tag name, name of the term, and the is_obsolete attribute concatenated togather with a delimiter (|). Returns : string Args : none =cut sub as_text{ my ($self) = @_; return $self->tagname()."|".$self->name()."|".($self->is_obsolete()||''); } =head2 display_text Title : display_text Usage : my $str = $ann->display_text(); Function: returns a string. Unlike as_text(), this method returns a string formatted as would be expected for te specific implementation. One can pass a callback as an argument which allows custom text generation; the callback is passed the current instance and any text returned Example : Returns : a string Args : [optional] callback =cut { my $DEFAULT_CB = sub { $_[0]->identifier || ''}; sub display_text { my ($self, $cb) = @_; $cb ||= $DEFAULT_CB; $self->throw("Callback must be a code reference") if ref $cb ne 'CODE'; return $cb->($self); } } =head2 hash_tree Title : hash_tree Usage : my $hashtree = $value->hash_tree Function: For supporting the AnnotationI interface just returns the value as a hashref with the key 'value' pointing to the value Returns : hashrf Args : none =cut sub hash_tree{ my ($self) = @_; my $h = {}; $h->{'name'} = $self->name(); $h->{'identifier'} = $self->identifier(); $h->{'definition'} = $self->definition(); $h->{'synonyms'} = [$self->get_synonyms()]; } =head2 tagname Title : tagname Usage : $obj->tagname($newval) Function: Get/set the tagname for this annotation value. Setting this is optional. If set, it obviates the need to provide a tag to AnnotationCollection when adding this object. This is aliased to ontology() here. Example : Returns : value of tagname (a scalar) Args : new value (a scalar, optional) =cut sub tagname{ my $self = shift; return $self->ontology(@_) if @_; # if in get mode we need to get the name from the ontology my $ont = $self->ontology(); return ref($ont) ? $ont->name() : $ont; } =head1 Methods for Bio::Ontology::TermI compliance =cut =head2 term Title : term Usage : $obj->term($newval) Function: Get/set the Bio::Ontology::TermI implementing object. We implement TermI by composition, and this method sets/gets the object we delegate to. Example : Returns : value of term (a Bio::Ontology::TermI compliant object) Args : new value (a Bio::Ontology::TermI compliant object, optional) =cut sub term{ my ($self,$value) = @_; if( defined $value) { $self->{'term'} = $value; } if(! exists($self->{'term'})) { $self->{'term'} = Bio::Ontology::Term->new(); } return $self->{'term'}; } =head2 identifier Title : identifier Usage : $term->identifier( "0003947" ); or print $term->identifier(); Function: Set/get for the identifier of this Term. Returns : The identifier [scalar]. Args : The identifier [scalar] (optional). =cut sub identifier { return shift->term()->identifier(@_); } # identifier =head2 name Title : name Usage : $term->name( "N-acetylgalactosaminyltransferase" ); or print $term->name(); Function: Set/get for the name of this Term. Returns : The name [scalar]. Args : The name [scalar] (optional). =cut sub name { return shift->term()->name(@_); } # name =head2 definition Title : definition Usage : $term->definition( "Catalysis of ..." ); or print $term->definition(); Function: Set/get for the definition of this Term. Returns : The definition [scalar]. Args : The definition [scalar] (optional). =cut sub definition { return shift->term()->definition(@_); } # definition =head2 ontology Title : ontology Usage : $term->ontology( $top ); or $top = $term->ontology(); Function: Set/get for a relationship between this Term and another Term (e.g. the top level of the ontology). Returns : The ontology of this Term [TermI]. Args : The ontology of this Term [TermI or scalar -- which becomes the name of the catagory term] (optional). =cut sub ontology { return shift->term()->ontology(@_); } =head2 is_obsolete Title : is_obsolete Usage : $term->is_obsolete( 1 ); or if ( $term->is_obsolete() ) Function: Set/get for the obsoleteness of this Term. Returns : the obsoleteness [0 or 1]. Args : the obsoleteness [0 or 1] (optional). =cut sub is_obsolete { return shift->term()->is_obsolete(@_); } # is_obsolete =head2 comment Title : comment Usage : $term->comment( "Consider the term ..." ); or print $term->comment(); Function: Set/get for an arbitrary comment about this Term. Returns : A comment. Args : A comment (optional). =cut sub comment { return shift->term()->comment(@_); } # comment =head2 get_synonyms Title : get_synonyms() Usage : @aliases = $term->get_synonyms(); Function: Returns a list of aliases of this Term. Returns : A list of aliases [array of [scalar]]. Args : =cut sub get_synonyms { return shift->term()->get_synonyms(@_); } # get_synonyms =head2 add_synonym Title : add_synonym Usage : $term->add_synonym( @asynonyms ); or $term->add_synonym( $synonym ); Function: Pushes one or more synonyms into the list of synonyms. Returns : Args : One synonym [scalar] or a list of synonyms [array of [scalar]]. =cut sub add_synonym { return shift->term()->add_synonym(@_); } # add_synonym =head2 remove_synonyms Title : remove_synonyms() Usage : $term->remove_synonyms(); Function: Deletes (and returns) the synonyms of this Term. Returns : A list of synonyms [array of [scalar]]. Args : =cut sub remove_synonyms { return shift->term()->remove_synonyms(@_); } # remove_synonyms =head2 get_dblinks Title : get_dblinks() Usage : @ds = $term->get_dblinks(); Function: Returns a list of each dblinks of this GO term. Returns : A list of dblinks [array of [scalars]]. Args : Note : this is deprecated in favor of get_dbxrefs(), which works with strings or L instances =cut sub get_dblinks { my $self = shift; $self->deprecated('get_dblinks() is deprecated; use get_dbxrefs()'); return $self->term->get_dbxrefs(@_); } # get_dblinks =head2 get_dbxrefs Title : get_dbxrefs() Usage : @ds = $term->get_dbxrefs(); Function: Returns a list of each dblinks of this GO term. Returns : A list of dblinks [array of [scalars] or Bio::Annotation::DBLink instances]. Args : =cut sub get_dbxrefs { return shift->term->get_dbxrefs(@_); } # get_dblinks =head2 add_dblink Title : add_dblink Usage : $term->add_dblink( @dbls ); or $term->add_dblink( $dbl ); Function: Pushes one or more dblinks into the list of dblinks. Returns : Args : One dblink [scalar] or a list of dblinks [array of [scalars]]. Note : this is deprecated in favor of add_dbxref(), which works with strings or L instances =cut sub add_dblink { my $self = shift; $self->deprecated('add_dblink() is deprecated; use add_dbxref()'); return $self->term->add_dbxref(@_); } # add_dblink =head2 add_dbxref Title : add_dbxref Usage : $term->add_dbxref( @dbls ); or $term->add_dbxref( $dbl ); Function: Pushes one or more dblinks into the list of dblinks. Returns : Args : =cut sub add_dbxref { return shift->term->add_dbxref(@_); } =head2 remove_dblinks Title : remove_dblinks() Usage : $term->remove_dblinks(); Function: Deletes (and returns) the definition references of this GO term. Returns : A list of definition references [array of [scalars]]. Args : Note : this is deprecated in favor of remove_dbxrefs(), which works with strings or L instances =cut sub remove_dblinks { my $self = shift; $self->deprecated('remove_dblinks() is deprecated; use remove_dbxrefs()'); return $self->term->remove_dbxrefs(@_); } # remove_dblinks =head2 remove_dbxrefs Title : remove_dbxrefs() Usage : $term->remove_dbxrefs(); Function: Deletes (and returns) the definition references of this GO term. Returns : A list of definition references [array of [scalars]]. Args : =cut sub remove_dbxrefs { return shift->term->remove_dbxrefs(@_); } =head2 get_secondary_ids Title : get_secondary_ids Usage : @ids = $term->get_secondary_ids(); Function: Returns a list of secondary identifiers of this Term. Secondary identifiers mostly originate from merging terms, or possibly also from splitting terms. Returns : A list of secondary identifiers [array of [scalar]] Args : =cut sub get_secondary_ids { return shift->term->get_secondary_ids(@_); } # get_secondary_ids =head2 add_secondary_id Title : add_secondary_id Usage : $term->add_secondary_id( @ids ); or $term->add_secondary_id( $id ); Function: Adds one or more secondary identifiers to this term. Returns : Args : One or more secondary identifiers [scalars] =cut sub add_secondary_id { return shift->term->add_secondary_id(@_); } # add_secondary_id =head2 remove_secondary_ids Title : remove_secondary_ids Usage : $term->remove_secondary_ids(); Function: Deletes (and returns) the secondary identifiers of this Term. Returns : The previous list of secondary identifiers [array of [scalars]] Args : =cut sub remove_secondary_ids { return shift->term->remove_secondary_ids(@_); } # remove_secondary_ids 1;