=head1 LICENSE Copyright (c) 1999-2013 The European Bioinformatics Institute and Genome Research Limited. All rights reserved. This software is distributed under a modified Apache license. For license details, please see http://www.ensembl.org/info/about/legal/code_licence.html =head1 CONTACT Please email comments or questions to the public Ensembl developers list at . Questions may also be sent to the Ensembl help desk at . =cut # # Ensembl module for Bio::EnsEMBL::Variation::DBSQL::GenotypeCodeAdaptor # # Copyright (c) 2011 Ensembl # # You may distribute this module under the same terms as perl itself # # =head1 NAME Bio::EnsEMBL::Variation::DBSQL::GenotypeCodeAdaptor =head1 SYNOPSIS $reg = 'Bio::EnsEMBL::Registry'; $reg->load_registry_from_db(-host => 'ensembldb.ensembl.org',-user => 'anonymous'); $va = $reg->get_adaptor("human","variation","genotypecode"); =head1 DESCRIPTION This adaptor provides database connectivity for GenotypeCode objects. GenotypeCodes may be retrieved from the Ensembl variation database by several means using this module. GenotypeCode objects are internal objects utilised by the CompressedGenotype adaptor - they are not intended for external use. =head1 METHODS =cut use strict; use warnings; package Bio::EnsEMBL::Variation::DBSQL::GenotypeCodeAdaptor; use Bio::EnsEMBL::Variation::DBSQL::BaseAdaptor; use Bio::EnsEMBL::Variation::GenotypeCode; use DBI qw(:sql_types); our @ISA = ('Bio::EnsEMBL::Variation::DBSQL::BaseAdaptor'); sub fetch_all_by_dbID_list { my ($self, $id_list_ref) = @_; if(!defined($id_list_ref) || ref($id_list_ref) ne 'ARRAY') { throw("id_list list reference argument is required"); } return [] if(!@$id_list_ref); my @out; # mysql is faster and we ensure that we do not exceed the max query size by # splitting large queries into smaller queries of 200 ids my $max_size = 200; my @id_list = @$id_list_ref; while(@id_list) { my @ids; if(@id_list > $max_size) { @ids = splice(@id_list, 0, $max_size); } else { @ids = splice(@id_list, 0); } my $id_str; if(@ids > 1) { $id_str = " IN (" . join(',', @ids). ")"; } else { $id_str = " = ?"; $self->bind_param_generic_fetch($ids[0],SQL_INTEGER); } my $constraint = "gc.genotype_code_id $id_str"; push @out, @{$self->generic_fetch($constraint)}; } return \@out; } # sub fetch_all_single_bp { my $self = shift; my $constraint = "length(ac.allele) = 1"; return $self->generic_fetch($constraint); } sub _objs_from_sth { my $self = shift; my $sth = shift; my $ploidy = $self->ploidy; my ($gt_code_id, $haplotype_id, $allele, $phased); my (@result, %gts); $sth->bind_columns(\$gt_code_id, \$haplotype_id, \$allele, \$phased); $gts{defined($phased) ? $phased : 'NULL'}{$gt_code_id}{$haplotype_id} = $allele while $sth->fetch; foreach $phased(keys %gts) { foreach $gt_code_id(keys %{$gts{$phased}}) { my @gt = map {$gts{$phased}{$gt_code_id}{$_}} sort {$a <=> $b} keys %{$gts{$phased}{$gt_code_id}}; # splice it down to ploidy size @gt = splice @gt, 0, $ploidy; push @result, Bio::EnsEMBL::Variation::GenotypeCode->new_fast({ dbID => $gt_code_id, genotype => \@gt, phased => $phased eq 'NULL' ? undef : $phased, }); } } return \@result; } # method used by superclass to construct SQL sub _tables { return (['genotype_code','gc'],['allele_code','ac']); } sub _columns { return qw( gc.genotype_code_id gc.haplotype_id ac.allele gc.phased ); } sub _default_where_clause { return 'gc.allele_code_id = ac.allele_code_id'; } 1;