# $Id: RandomFactory.pm 15635 2009-04-14 19:11:13Z cjfields $ # # Module for Bio::PhyloNetwork::RandomFactory # # Please direct questions and support issues to # # Cared for by Gabriel Cardona # # Copyright Gabriel Cardona # # You may distribute this module under the same terms as perl itself # POD documentation - main docs before the code =head1 NAME Bio::PhyloNetwork::RandomFactory - Module to generate random Phylogenetic Networks =head1 SYNOPSIS use strict; use warnings; use Bio::PhyloNetwork; use Bio::PhyloNetwork::RandomFactory; # Will generate at random all the 66 binary tree-child phylogenetic # networks with 3 leaves my $factory=Bio::PhyloNetwork::RandomFactory->new(-numleaves=>3,-norepeat=>1); my @nets; for (my $i=0; $i<66; $i++) { my $net=$factory->next_network(); push @nets,$net; print "".(scalar @nets).": ".$net->eNewick()."\n"; } =head1 DESCRIPTION Builds a random (binary tree-child) phylogenetic network each time next_network is called. =head1 AUTHOR Gabriel Cardona, gabriel(dot)cardona(at)uib(dot)es =head1 SEE ALSO L =head1 APPENDIX The rest of the documentation details each of the object methods. =cut package Bio::PhyloNetwork::RandomFactory; use strict; use warnings; use base qw(Bio::Root::Root); use Bio::PhyloNetwork; use Math::Random; use Bio::Tree::RandomFactory; =head2 new Title : new Usage : my $factory = new Bio::PhyloNetwork::RandomFactory(); Function: Creates a new Bio::PhyloNetwork::RandomFactory Returns : Bio::PhyloNetwork::RandomFactory Args : -numleaves => integer OR -leaves => reference to an array (of leaves names) -numhybrids => integer [optional] -norepeat => boolean [optional] Returns a Bio::PhyloNetwork::RandomFactory object. Such an object will create random binary tree-child phylogenetic networks each time next_network is called. If the parameter -leaves=E\@leaves is given, then the set of leaves of these networks will be @leaves. If it is given the parameter -numleaves=E$numleaves, then the set of leaves will be "l1"..."l$numleaves". If the parameter -numhybrids=E$numhybrids is given, then the generated networks will have exactly $numhybrids hybrid nodes. Note that, necessarily, $numhybrids E $numleaves. Otherwise, the number of hybrid nodes will be chosen at random for each call of next_network. If the parameter -norepeat=E1 is given, then successive calls of next_network will give non-isomorphic networks. =cut sub new { my ($pkg,@args)=@_; my $self=$pkg->SUPER::new(@args); my ($leavesR,$numleaves,$numhybrids,$norepeat)= $self->_rearrange([qw(LEAVES NUMLEAVES NUMHYBRIDS NOREPEAT)],@args); my @leaves; if ((! defined $leavesR) && (defined $numleaves)) { @leaves=map {"l$_"} (1..$numleaves); $leavesR=\@leaves; } if (! defined $leavesR) { $self->throw("No leaves set neither numleaves given"); } $norepeat ||= 0; $self->{leaves}=\@leaves; $self->{numleaves}=$numleaves; $self->{numhybrids}=$numhybrids if defined $numhybrids; $self->{norepeat}=$norepeat; $self->{found}=[]; $self->{tree_factory}=Bio::Tree::RandomFactory->new(-taxa => \@leaves); bless($self,$pkg); } =head2 next_network Title : next_network Usage : my $net=$factory->next_network() Function: returns a random network Returns : Bio::PhyloNetwork Args : none =cut sub next_network { my ($self)=@_; my $numleaves=$self->{numleaves}; my @found=@{$self->{found}}; my $numhybrids; START: if (! defined $self->{numhybrids}) { $numhybrids=int(rand($numleaves)); } else { $numhybrids=$self->{numhybrids}; } my $tf=$self->{tree_factory}; my $tree=$tf->next_tree; my $net=Bio::PhyloNetwork->new(-tree=>$tree); for (my $i=1; $i<=$numhybrids; $i++) { $net=random_attack($net,$i); } if ($self->{norepeat}) { foreach my $ant (@found) { goto START if $net->is_mu_isomorphic($ant); } push @found,$net; $self->{found}=\@found; } return $net; } sub random_attack { my ($net,$lbl)=@_; my $graph=$net->{graph}; my ($u1,$v1,$u2,$v2); do { my $e1=$graph->random_edge; my $e2=$graph->random_edge; $u1=$e1->[0]; $v1=$e1->[1]; $u2=$e2->[0]; $v2=$e2->[1]; } while (! $net->is_attackable($u1,$v1,$u2,$v2,$lbl)); $net->do_attack($u1,$v1,$u2,$v2,$lbl); return $net; } 1;