hsa00010 Glycolysis / Gluconeogenesis ACSS1 ACSS2 ADH1A ADH1B ADH1C ADH4 ADH5 ADH6 ADH7 ADPGK AKR1A1 ALDH1A3 ALDH1B1 ALDH2 ALDH3A1 ALDH3A2 ALDH3B1 ALDH3B2 ALDH7A1 ALDH9A1 ALDOA ALDOB ALDOC BPGM DLAT DLD ENO1 ENO2 ENO3 FBP1 FBP2 G6PC G6PC2 GALM GAPDH GAPDHS GCK GPI HK1 HK2 HK3 LDHA LDHAL6A LDHAL6B LDHB LDHC PCK1 PCK2 PDHA1 PDHA2 PDHB PFKL PFKM PFKP PGAM1 PGAM2 PGAM4 PGK1 PGK2 PGM1 PGM2 PKLR PKM2 TPI1 hsa00020 Citrate cycle (TCA cycle) ACLY ACO1 ACO2 CS DLAT DLD DLST FH IDH1 IDH2 IDH3A IDH3B IDH3G LOC283398 MDH1 MDH2 OGDH OGDHL PC PCK1 PCK2 PDHA1 PDHA2 PDHB SDHA SDHB SDHC SDHD SUCLA2 SUCLG1 SUCLG2 hsa00030 Pentose phosphate pathway ALDOA ALDOB ALDOC DERA FBP1 FBP2 G6PD GPI H6PD LOC729020 PFKL PFKM PFKP PGD PGLS PGM1 PGM2 PRPS1 PRPS1L1 PRPS2 RBKS RPE RPIA TALDO1 TKT TKTL1 TKTL2 hsa00040 Pentose and glucuronate interconversions AKR1B1 CRYL1 DCXR DHDH GUSB LOC729020 RPE UGDH UGP2 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 XYLB hsa00051 Fructose and mannose metabolism AKR1B1 AKR1B10 ALDOA ALDOB ALDOC FBP1 FBP2 FPGT FUK GMDS GMPPA GMPPB HK1 HK2 HK3 KHK MPI MTMR1 MTMR2 MTMR6 MTMR7 PFKFB1 PFKFB2 PFKFB3 PFKFB4 PFKL PFKM PFKP PHPT1 PMM1 PMM2 SORD TPI1 TSTA3 hsa00052 Galactose metabolism AKR1B1 B4GALT1 B4GALT2 G6PC G6PC2 GAA GALE GALK1 GALK2 GALT GANC GCK GLA GLB1 HK1 HK2 HK3 LALBA LCT MGAM PFKL PFKM PFKP PGM1 PGM2 UGP2 hsa00053 Ascorbate and aldarate metabolism ALDH1B1 ALDH2 ALDH3A2 ALDH7A1 ALDH9A1 MIOX UGDH UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 hsa00061 Fatty acid biosynthesis ACACA ACACB FASN MCAT OLAH OXSM hsa00062 Fatty acid elongation in mitochondria ACAA2 ECHS1 HADH HADHA HADHB MECR PPT1 PPT2 hsa00071 Fatty acid metabolism ACAA1 ACAA2 ACADL ACADM ACADS ACADSB ACADVL ACAT1 ACAT2 ACOX1 ACOX3 ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 ADH1A ADH1B ADH1C ADH4 ADH5 ADH6 ADH7 ALDH1B1 ALDH2 ALDH3A2 ALDH7A1 ALDH9A1 CPT1A CPT1B CPT1C CPT2 CYP4A11 CYP4A22 DCI ECHS1 EHHADH GCDH HADH HADHA HADHB PECI hsa00072 Synthesis and degradation of ketone bodies ACAT1 ACAT2 BDH1 BDH2 HMGCL HMGCS1 HMGCS2 OXCT1 OXCT2 hsa00100 Steroid biosynthesis CEL CYP27B1 CYP51A1 DHCR24 DHCR7 EBP FDFT1 HSD17B7 LIPA LSS NSDHL SC4MOL SC5DL SOAT1 SOAT2 SQLE TM7SF2 hsa00120 Primary bile acid biosynthesis ACOX2 AKR1C4 AKR1D1 AMACR BAAT CH25H CYP27A1 CYP39A1 CYP46A1 CYP7A1 CYP7B1 CYP8B1 HSD17B4 HSD3B7 SCP2 SLC27A5 hsa00130 Ubiquinone and other terpenoid-quinone biosynthesis COQ2 COQ3 COQ5 COQ6 COQ7 HPD TAT hsa00140 Steroid hormone biosynthesis AKR1C1 AKR1C2 AKR1C3 AKR1C4 AKR1D1 COMT CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP19A1 CYP1A1 CYP1B1 CYP21A2 CYP3A4 CYP3A43 CYP3A5 CYP3A7 CYP7A1 CYP7B1 HSD11B1 HSD11B2 HSD17B1 HSD17B12 HSD17B2 HSD17B3 HSD17B6 HSD17B7 HSD17B8 HSD3B1 HSD3B2 SRD5A1 SRD5A2 SRD5A3 STS SULT1E1 SULT2B1 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 hsa00190 Oxidative phosphorylation 100133737 ATP12A ATP4A ATP4B ATP5A1 ATP5B ATP5C1 ATP5D ATP5E ATP5F1 ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2 ATP5L ATP5O ATP6 ATP6AP1 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H ATP8 COX1 COX10 COX11 COX15 COX17 COX2 COX3 COX4I1 COX4I2 COX5A COX5B COX6A1 COX6A2 COX6B1 COX6B2 COX6C COX7A1 COX7A2 COX7A2L COX7B COX7B2 COX7C COX8A COX8C CYC1 CYTB LHPP LOC100130247 LOC390424 LOC644310 LOC727947 ND1 ND2 ND3 ND4 ND4L ND5 ND6 NDUFA1 NDUFA10 NDUFA11 NDUFA2 NDUFA3 NDUFA4 NDUFA4L2 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFB1 NDUFB10 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 PPA1 PPA2 SDHA SDHB SDHC SDHD TCIRG1 UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRHL UQCRQ hsa00230 Purine metabolism ADA ADCY1 ADCY10 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADK ADSL ADSS ADSSL1 AK1 AK2 AK4 AK5 AK7 ALLC AMPD1 AMPD2 AMPD3 APRT ATIC C17orf48 CANT1 DCK DGUOK ENPP1 ENPP3 ENTPD1 ENTPD2 ENTPD3 ENTPD4 ENTPD5 ENTPD6 ENTPD8 FHIT GART GDA GMPR GMPR2 GMPS GUCY1A2 GUCY1A3 GUCY1B3 GUCY2C GUCY2D GUCY2F GUK1 HPRT1 IMPDH1 IMPDH2 ITPA NME1 NME1-NME2 NME2 NME3 NME4 NME5 NME6 NME7 NPR1 NPR2 NT5C NT5C1A NT5C1B NT5C2 NT5C3 NT5E NT5M NUDT2 NUDT5 NUDT9 PAICS PAPSS1 PAPSS2 PDE10A PDE11A PDE1A PDE1B PDE1C PDE2A PDE3A PDE3B PDE4A PDE4B PDE4C PDE4D PDE5A PDE6A PDE6B PDE6C PDE6D PDE6G PDE6H PDE7A PDE7B PDE8A PDE8B PDE9A PFAS PGM1 PGM2 PKLR PKM2 PNP PNPT1 POLA1 POLA2 POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLR1A POLR1B POLR1C POLR1D POLR1E POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J2 POLR2J3 POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3F POLR3G POLR3GL POLR3H POLR3K PPAT PRHOXNB PRIM1 PRIM2 PRPS1 PRPS1L1 PRPS2 PRUNE RRM1 RRM2 RRM2B XDH ZNRD1 hsa00232 Caffeine metabolism CYP1A2 CYP2A13 CYP2A6 CYP2A7 NAT1 NAT2 XDH hsa00240 Pyrimidine metabolism AK3 CAD CANT1 CDA CMPK1 CMPK2 CTPS CTPS2 DCK DCTD DHODH DPYD DPYS DTYMK DUT ENTPD1 ENTPD3 ENTPD4 ENTPD5 ENTPD6 ENTPD8 ITPA NME1 NME1-NME2 NME2 NME3 NME4 NME5 NME6 NME7 NT5C NT5C1A NT5C1B NT5C2 NT5C3 NT5E NT5M NUDT2 PNP PNPT1 POLA1 POLA2 POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLR1A POLR1B POLR1C POLR1D POLR1E POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J2 POLR2J3 POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3F POLR3G POLR3GL POLR3H POLR3K PRIM1 PRIM2 RRM1 RRM2 RRM2B TK1 TK2 TXNRD1 TXNRD2 TXNRD3 TYMP TYMS UCK1 UCK2 UCKL1 UMPS UPB1 UPP1 UPP2 UPRT ZNRD1 hsa00250 Alanine, aspartate and glutamate metabolism ABAT ACY3 ADSL ADSS ADSSL1 AGXT AGXT2 ALDH4A1 ALDH5A1 ASL ASNS ASPA ASS1 CAD CPS1 DDO GAD1 GAD2 GFPT1 GFPT2 GLS GLS2 GLUD1 GLUD2 GLUL GOT1 GOT2 GPT GPT2 IL4I1 NIT2 PPAT hsa00260 Glycine, serine and threonine metabolism AGXT AGXT2 ALAS1 ALAS2 AMT AOC2 AOC3 BHMT CBS CHDH CTH DAO DLD DMGDH GAMT GATM GCAT GLDC GLYCTK GNMT MAOA MAOB PHGDH PIPOX PSAT1 PSPH SARDH SDS SHMT1 SHMT2 SRR hsa00270 Cysteine and methionine metabolism ADI1 AHCY AHCYL1 AHCYL2 AMD1 APIP BHMT CBS CDO1 CTH DNMT1 DNMT3A DNMT3B DNMT3L ENOPH1 GOT1 GOT2 IL4I1 LDHA LDHAL6A LDHAL6B LDHB LDHC MAT1A MAT2A MAT2B MPST MTAP MTR SDS SMS SRM TAT TRDMT1 hsa00280 Valine, leucine and isoleucine degradation ABAT ACAA1 ACAA2 ACAD8 ACADM ACADS ACADSB ACAT1 ACAT2 ALDH1B1 ALDH2 ALDH3A2 ALDH6A1 ALDH7A1 ALDH9A1 AOX1 AUH BCAT1 BCAT2 BCKDHA BCKDHB DBT DLD ECHS1 EHHADH HADH HADHA HADHB HIBADH HIBCH HMGCL HMGCS1 HMGCS2 HSD17B10 IL4I1 IVD MCCC1 MCCC2 MCEE MUT OXCT1 OXCT2 PCCA PCCB hsa00290 Valine, leucine and isoleucine biosynthesis BCAT1 BCAT2 IARS IARS2 LARS LARS2 PDHA1 PDHA2 PDHB VARS VARS2 hsa00300 Lysine biosynthesis AADAT AASDH AASDHPPT AASS hsa00310 Lysine degradation AADAT AASDH AASDHPPT AASS ACAT1 ACAT2 ALDH1B1 ALDH2 ALDH3A2 ALDH7A1 ALDH9A1 ASH1L BBOX1 DLST DOT1L ECHS1 EHHADH EHMT1 EHMT2 GCDH GLT25D1 GLT25D2 HADH HADHA NSD1 OGDH OGDHL PIPOX PLOD1 PLOD2 PLOD3 SETD1A SETD1B SETD2 SETD7 SETD8 SETDB1 SETDB2 SETMAR SUV39H1 SUV39H2 SUV420H1 SUV420H2 TMLHE WHSC1 WHSC1L1 hsa00330 Arginine and proline metabolism ABP1 ACY1 ADC AGMAT ALDH18A1 ALDH1B1 ALDH2 ALDH3A2 ALDH4A1 ALDH7A1 ALDH9A1 AMD1 ARG1 ARG2 ASL ASS1 CKB CKM CKMT1A CKMT1B CKMT2 CPS1 DAO GAMT GATM GLS GLS2 GLUD1 GLUD2 GLUL GOT1 GOT2 LAP3 MAOA MAOB NAGS NOS1 NOS2 NOS3 OAT ODC1 OTC P4HA1 P4HA2 P4HA3 PRODH PRODH2 PYCR1 PYCR2 PYCRL SAT1 SAT2 SMS SRM hsa00340 Histidine metabolism ABP1 ACY3 ALDH1A3 ALDH1B1 ALDH2 ALDH3A1 ALDH3A2 ALDH3B1 ALDH3B2 ALDH7A1 ALDH9A1 AMDHD1 ASPA CNDP1 DDC FTCD HAL HDC HEMK1 HNMT LCMT1 LCMT2 MAOA MAOB METTL2B METTL6 TRMT11 UROC1 WBSCR22 hsa00350 Tyrosine metabolism ADH1A ADH1B ADH1C ADH4 ADH5 ADH6 ADH7 ALDH1A3 ALDH3A1 ALDH3B1 ALDH3B2 AOC2 AOC3 AOX1 COMT DBH DCT DDC FAH GOT1 GOT2 GSTZ1 HEMK1 HGD HPD IL4I1 LCMT1 LCMT2 MAOA MAOB METTL2B METTL6 MIF PNMT TAT TH TPO TRMT11 TYR TYRP1 WBSCR22 hsa00360 Phenylalanine metabolism ALDH1A3 ALDH3A1 ALDH3B1 ALDH3B2 AOC2 AOC3 DDC GOT1 GOT2 HPD IL4I1 MAOA MAOB MIF PAH PRDX6 TAT hsa00380 Tryptophan metabolism AADAT AANAT ABP1 ACAT1 ACAT2 ACMSD AFMID ALDH1B1 ALDH2 ALDH3A2 ALDH7A1 ALDH9A1 AOX1 ASMT CAT CYP1A1 CYP1A2 CYP1B1 DDC ECHS1 EHHADH GCDH HAAO HADH HADHA IDO1 IDO2 IL4I1 INMT KMO KYNU MAOA MAOB OGDH OGDHL TDO2 TPH1 TPH2 WARS WARS2 hsa00400 Phenylalanine, tyrosine and tryptophan biosynthesis GOT1 GOT2 IL4I1 PAH TAT hsa00410 beta-Alanine metabolism ABAT ACADM ALDH1B1 ALDH2 ALDH3A2 ALDH7A1 ALDH9A1 AOC2 AOC3 CNDP1 DPYD DPYS ECHS1 EHHADH GAD1 GAD2 HADHA HIBCH MLYCD SMS SRM UPB1 hsa00430 Taurine and hypotaurine metabolism ADO BAAT CDO1 CSAD GAD1 GAD2 GGT1 GGT5 GGT6 GGT7 hsa00450 Selenoamino acid metabolism AHCY AHCYL1 AHCYL2 CBS CTH GGT1 GGT5 GGT6 GGT7 HEMK1 LCMT1 LCMT2 MARS MARS2 MAT1A MAT2A MAT2B METTL2B METTL6 PAPSS1 PAPSS2 SCLY SEPHS1 SEPHS2 TRMT11 WBSCR22 hsa00460 Cyanoamino acid metabolism GBA3 GGT1 GGT5 GGT6 GGT7 SHMT1 SHMT2 hsa00471 D-Glutamine and D-glutamate metabolism GLS GLS2 GLUD1 GLUD2 hsa00472 D-Arginine and D-ornithine metabolism DAO hsa00480 Glutathione metabolism ANPEP G6PD GCLC GCLM GGCT GGT1 GGT5 GGT6 GGT7 GPX1 GPX2 GPX3 GPX4 GPX5 GPX6 GPX7 GSR GSS GSTA1 GSTA2 GSTA3 GSTA4 GSTA5 GSTK1 GSTM1 GSTM2 GSTM3 GSTM4 GSTM5 GSTO1 GSTO2 GSTP1 GSTT1 GSTT2 GSTZ1 IDH1 IDH2 LAP3 MGST1 MGST2 MGST3 ODC1 OPLAH PGD RRM1 RRM2 RRM2B SMS SRM TXNDC12 hsa00500 Starch and sucrose metabolism AGL AMY1A AMY1B AMY1C AMY2A AMY2B ENPP1 ENPP3 G6PC G6PC2 GAA GANC GBA3 GBE1 GCK GPI GUSB GYS1 GYS2 HK1 HK2 HK3 MGAM PGM1 PGM2 PGM2L1 PYGB PYGL PYGM SI TREH UGDH UGP2 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UXS1 hsa00510 N-Glycan biosynthesis ALG1 ALG10 ALG10B ALG11 ALG12 ALG13 ALG14 ALG2 ALG3 ALG5 ALG6 ALG8 ALG9 B4GALT1 B4GALT2 B4GALT3 DAD1 DDOST DOLK DOLPP1 DPAGT1 DPM1 DPM2 DPM3 FUT8 GANAB MAN1A1 MAN1A2 MAN1B1 MAN1C1 MAN2A1 MAN2A2 MGAT1 MGAT2 MGAT3 MGAT4A MGAT4B MGAT4C MGAT5 MGAT5B MOGS RFT1 RPN1 RPN2 ST6GAL1 STT3A STT3B TUSC3 hsa00511 Other glycan degradation AGA ENGASE FUCA1 FUCA2 GBA GLB1 HEXA HEXB MAN2B1 MAN2B2 MAN2C1 MANBA NEU1 NEU2 NEU3 NEU4 hsa00512 O-Glycan biosynthesis B3GNT6 B4GALT5 C1GALT1 C1GALT1C1 GALNT1 GALNT10 GALNT11 GALNT12 GALNT13 GALNT14 GALNT2 GALNT3 GALNT4 GALNT5 GALNT6 GALNT7 GALNT8 GALNT9 GALNTL1 GALNTL2 GALNTL4 GALNTL5 GALNTL6 GCNT1 GCNT3 GCNT4 ST3GAL1 ST3GAL2 ST6GALNAC1 WBSCR17 hsa00514 O-Mannosyl glycan biosynthesis POMGNT1 POMT1 POMT2 hsa00520 Amino sugar and nucleotide sugar metabolism AMDHD2 CHIA CHIT1 CMAS CYB5R1 CYB5R3 FPGT FUK GALE GALK1 GALK2 GALT GCK GFPT1 GFPT2 GMDS GMPPA GMPPB GNE GNPDA1 GNPDA2 GNPNAT1 GPI HEXA HEXB HK1 HK2 HK3 MPI NAGK NANP NANS NPL PGM1 PGM2 PGM3 PMM1 PMM2 RENBP TSTA3 UAP1 UAP1L1 UGDH UGP2 UXS1 hsa00524 Butirosin and neomycin biosynthesis GCK HK1 HK2 HK3 hsa00531 Glycosaminoglycan degradation ARSB GALNS GLB1 GNS GUSB HEXA HEXB HGSNAT HPSE HPSE2 HYAL1 HYAL2 HYAL3 HYAL4 IDS IDUA NAGLU SGSH SPAM1 hsa00532 Glycosaminoglycan biosynthesis - chondroitin sulfate B3GALT6 B3GAT1 B3GAT2 B3GAT3 B4GALT7 CHPF CHPF2 CHST11 CHST12 CHST13 CHST14 CHST15 CHST3 CHST7 CHSY1 CHSY3 CSGALNACT1 CSGALNACT2 DSE UST XYLT1 XYLT2 hsa00533 Glycosaminoglycan biosynthesis - keratan sulfate B3GNT1 B3GNT2 B3GNT7 B4GALT1 B4GALT2 B4GALT3 B4GALT4 CHST1 CHST2 CHST4 CHST6 FUT8 ST3GAL1 ST3GAL2 ST3GAL3 hsa00534 Glycosaminoglycan biosynthesis - heparan sulfate B3GALT6 B3GAT1 B3GAT2 B3GAT3 B4GALT7 EXT1 EXT2 EXTL1 EXTL2 EXTL3 GLCE HS2ST1 HS3ST1 HS3ST2 HS3ST3A1 HS3ST3B1 HS3ST5 HS6ST1 HS6ST2 HS6ST3 NDST1 NDST2 NDST3 NDST4 XYLT1 XYLT2 hsa00561 Glycerolipid metabolism AGK AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT6 AGPAT9 AKR1A1 AKR1B1 ALDH1B1 ALDH2 ALDH3A2 ALDH7A1 ALDH9A1 CEL DAK DGAT1 DGAT2 DGKA DGKB DGKD DGKE DGKG DGKH DGKI DGKQ DGKZ GK GK2 GLA GLYCTK GPAM GPAT2 LCLAT1 LIPC LIPF LIPG LPL MBOAT1 MBOAT2 MGLL PNLIP PNLIPRP1 PNLIPRP2 PNPLA3 PPAP2A PPAP2B PPAP2C hsa00562 Inositol phosphate metabolism ALDH6A1 CDIPT IMPA1 IMPA2 INPP1 INPP4A INPP4B INPP5A INPP5B INPP5E INPP5J INPP5K INPPL1 IPMK IPPK ISYNA1 ITPK1 ITPKA ITPKB MINPP1 MIOX OCRL PI4K2A PI4K2B PI4KA PI4KB PIK3C2A PIK3C2B PIK3C2G PIK3C3 PIK3CA PIK3CB PIK3CD PIK3CG PIKFYVE PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PIP5KL1 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PTEN SYNJ1 SYNJ2 TPI1 hsa00563 Glycosylphosphatidylinositol(GPI)-anchor biosynthesis DPM2 GPAA1 GPLD1 PGAP1 PIGA PIGB PIGC PIGF PIGG PIGH PIGK PIGL PIGM PIGN PIGO PIGP PIGQ PIGS PIGT PIGU PIGV PIGW PIGX PIGY PIGZ hsa00564 Glycerophospholipid metabolism ACHE AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT6 AGPAT9 C17orf48 CDIPT CDS1 CDS2 CEPT1 CHAT CHKA CHKB CHPT1 CRLS1 DGKA DGKB DGKD DGKE DGKG DGKH DGKI DGKQ DGKZ EPT1 ETNK1 ETNK2 GNPAT GPAM GPAT2 GPD1 GPD1L GPD2 JMJD7-PLA2G4B LCAT LCLAT1 LPCAT1 LPCAT2 LPCAT3 LPCAT4 LPGAT1 LYPLA1 LYPLA2 MBOAT1 MBOAT2 MBOAT7 PCYT1A PCYT1B PCYT2 PEMT PGS1 PHOSPHO1 PISD PLA2G10 PLA2G12A PLA2G12B PLA2G15 PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PLD1 PLD2 PPAP2A PPAP2B PPAP2C PTDSS1 PTDSS2 TAZ hsa00565 Ether lipid metabolism AGPS CEPT1 CHPT1 ENPP2 ENPP6 EPT1 JMJD7-PLA2G4B LPCAT1 LPCAT2 LPCAT4 PAFAH1B1 PAFAH1B2 PAFAH1B3 PAFAH2 PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PLA2G7 PLD1 PLD2 PPAP2A PPAP2B PPAP2C hsa00590 Arachidonic acid metabolism AKR1C3 ALOX12 ALOX12B ALOX15 ALOX15B ALOX5 CBR1 CBR3 CYP2B6 CYP2C18 CYP2C19 CYP2C8 CYP2C9 CYP2E1 CYP2J2 CYP2U1 CYP4A11 CYP4A22 CYP4F2 CYP4F3 EPHX2 GGT1 GGT5 GGT6 GGT7 GPX1 GPX2 GPX3 GPX4 GPX5 GPX6 GPX7 HPGDS JMJD7-PLA2G4B LTA4H LTC4S PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PTGDS PTGES PTGES2 PTGIS PTGS1 PTGS2 TBXAS1 hsa00591 Linoleic acid metabolism AKR1B10 ALOX15 CYP1A2 CYP2C18 CYP2C19 CYP2C8 CYP2C9 CYP2E1 CYP2J2 CYP3A4 CYP3A43 CYP3A5 CYP3A7 JMJD7-PLA2G4B PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 hsa00592 alpha-Linolenic acid metabolism ACOX1 ACOX3 FADS2 JMJD7-PLA2G4B PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 hsa00600 Sphingolipid metabolism ACER1 ACER2 ACER3 ARSA ASAH1 ASAH2 ASAH2C B4GALT6 CERK DEGS1 DEGS2 ENPP7 GAL3ST1 GALC GBA GLA GLB1 KDSR NEU1 NEU2 NEU3 NEU4 PPAP2A PPAP2B PPAP2C SGMS1 SGMS2 SGPL1 SGPP1 SGPP2 SMPD1 SMPD2 SMPD3 SMPD4 SPHK1 SPHK2 SPTLC1 SPTLC2 UGCG UGT8 hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 100289720 ABO B3GALT1 B3GALT2 B3GALT5 B3GNT1 B3GNT2 B3GNT3 B3GNT4 B3GNT5 B4GALT1 B4GALT2 B4GALT3 B4GALT4 FUT1 FUT2 FUT3 FUT4 FUT5 FUT6 FUT7 FUT9 GCNT2 LOC100288842 ST3GAL3 ST3GAL4 ST3GAL6 ST8SIA1 hsa00603 Glycosphingolipid biosynthesis - globo series A4GALT B3GALNT1 B3GALT5 FUT1 FUT2 FUT9 GBGT1 GLA HEXA HEXB NAGA ST3GAL1 ST3GAL2 ST8SIA1 hsa00604 Glycosphingolipid biosynthesis - ganglio series B3GALT4 B4GALNT1 GLB1 HEXA HEXB SLC33A1 ST3GAL1 ST3GAL2 ST3GAL5 ST6GALNAC3 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA5 hsa00620 Pyruvate metabolism ACACA ACACB ACAT1 ACAT2 ACOT12 ACSS1 ACSS2 ACYP1 ACYP2 AKR1B1 ALDH1B1 ALDH2 ALDH3A2 ALDH7A1 ALDH9A1 DLAT DLD GLO1 GRHPR HAGH HAGHL LDHA LDHAL6A LDHAL6B LDHB LDHC LDHD MDH1 MDH2 ME1 ME2 ME3 PC PCK1 PCK2 PDHA1 PDHA2 PDHB PKLR PKM2 hsa00630 Glyoxylate and dicarboxylate metabolism ACO1 ACO2 AFMID CS GLYCTK GRHPR HAO1 HAO2 HYI MDH1 MDH2 MTHFD1 MTHFD1L MTHFD2 MTHFD2L PGP hsa00640 Propanoate metabolism ABAT ACACA ACACB ACADM ACAT1 ACAT2 ACSS1 ACSS2 ACSS3 ALDH1B1 ALDH2 ALDH3A2 ALDH6A1 ALDH7A1 ALDH9A1 ECHS1 EHHADH HADHA HIBCH LDHA LDHAL6A LDHAL6B LDHB LDHC LOC283398 MCEE MLYCD MUT PCCA PCCB SUCLA2 SUCLG1 SUCLG2 hsa00650 Butanoate metabolism AACS ABAT ACADS ACAT1 ACAT2 ACSM1 ACSM2A ACSM2B ACSM3 ACSM4 ACSM5 AKR1B10 ALDH5A1 BDH1 BDH2 ECHS1 EHHADH GAD1 GAD2 HADH HADHA HMGCL HMGCS1 HMGCS2 L2HGDH OXCT1 OXCT2 PDHA1 PDHA2 PDHB hsa00670 One carbon pool by folate ALDH1L1 AMT ATIC DHFR FTCD GART MTFMT MTHFD1 MTHFD1L MTHFD2 MTHFD2L MTHFR MTHFS MTR SHMT1 SHMT2 TYMS hsa00730 Thiamine metabolism MTMR1 MTMR2 MTMR6 MTMR7 NFS1 PHPT1 THTPA TPK1 hsa00740 Riboflavin metabolism ACP1 ACP2 ACP5 ACP6 ACPP ACPT ENPP1 ENPP3 FLAD1 MTMR1 MTMR2 MTMR6 MTMR7 PHPT1 RFK TYR hsa00750 Vitamin B6 metabolism AOX1 PDXK PDXP PHOSPHO2 PNPO PSAT1 hsa00760 Nicotinate and nicotinamide metabolism AOX1 BST1 C9orf95 CD38 ENPP1 ENPP3 NADK NADSYN1 NAMPT NMNAT1 NMNAT2 NMNAT3 NNMT NNT NT5C NT5C1A NT5C1B NT5C2 NT5C3 NT5E NT5M NUDT12 PNP QPRT hsa00770 Pantothenate and CoA biosynthesis BCAT1 BCAT2 COASY DPYD DPYS ENPP1 ENPP3 PANK1 PANK2 PANK3 PANK4 PPCDC PPCS UPB1 VNN1 VNN2 hsa00780 Biotin metabolism BTD HLCS hsa00785 Lipoic acid metabolism LIAS LIPT1 LIPT2 hsa00790 Folate biosynthesis ALPI ALPL ALPP ALPPL2 DHFR FPGS GCH1 GGH PTS QDPR SPR hsa00830 Retinol metabolism ADH1A ADH1B ADH1C ADH4 ADH5 ADH6 ADH7 ALDH1A1 ALDH1A2 AWAT2 BCMO1 CYP1A1 CYP1A2 CYP26A1 CYP26B1 CYP26C1 CYP2A13 CYP2A6 CYP2A7 CYP2B6 CYP2C18 CYP2C19 CYP2C8 CYP2C9 CYP3A4 CYP3A43 CYP3A5 CYP3A7 CYP4A11 CYP4A22 DGAT1 DGAT2 DHRS3 DHRS4 DHRS4L2 DHRS9 LRAT PNPLA4 RDH10 RDH11 RDH12 RDH16 RDH5 RDH8 RETSAT RPE65 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 hsa00860 Porphyrin and chlorophyll metabolism ALAD ALAS1 ALAS2 BLVRA BLVRB COX10 COX15 CP CPOX EARS2 EPRS FECH FTH1 FTL FTMT GUSB HCCS HMBS HMOX1 HMOX2 MMAB PPOX UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UROD UROS hsa00900 Terpenoid backbone biosynthesis ACAT1 ACAT2 DHDDS FDPS GGPS1 HMGCR HMGCS1 HMGCS2 IDI1 IDI2 MVD MVK PDSS1 PDSS2 PMVK hsa00903 Limonene and pinene degradation ALDH1B1 ALDH2 ALDH3A2 ALDH7A1 ALDH9A1 ECHS1 EHHADH HADHA hsa00910 Nitrogen metabolism AMT ASNS CA1 CA12 CA13 CA14 CA2 CA3 CA4 CA5A CA5B CA6 CA7 CA8 CA9 CPS1 CTH GLS GLS2 GLUD1 GLUD2 GLUL HAL hsa00920 Sulfur metabolism BPNT1 CHST11 CHST12 CHST13 PAPSS1 PAPSS2 SULT1A1 SULT1A2 SULT1A3 SULT1A4 SULT1E1 SULT2B1 SUOX hsa00970 Aminoacyl-tRNA biosynthesis AARS AARS2 CARS CARS2 DARS DARS2 EARS2 EPRS FARS2 FARSA FARSB GARS HARS HARS2 IARS IARS2 KARS LARS LARS2 MARS MARS2 MTFMT NARS NARS2 PARS2 PSTK QARS RARS RARS2 SARS SARS2 SEPSECS TARS TARS2 TARSL2 VARS VARS2 WARS WARS2 YARS YARS2 hsa00980 Metabolism of xenobiotics by cytochrome P450 ADH1A ADH1B ADH1C ADH4 ADH5 ADH6 ADH7 AKR1C1 AKR1C2 AKR1C3 AKR1C4 ALDH1A3 ALDH3A1 ALDH3B1 ALDH3B2 CYP1A1 CYP1A2 CYP1B1 CYP2B6 CYP2C18 CYP2C19 CYP2C8 CYP2C9 CYP2E1 CYP2F1 CYP2S1 CYP3A4 CYP3A43 CYP3A5 CYP3A7 DHDH EPHX1 GSTA1 GSTA2 GSTA3 GSTA4 GSTA5 GSTK1 GSTM1 GSTM2 GSTM3 GSTM4 GSTM5 GSTO1 GSTO2 GSTP1 GSTT1 GSTT2 GSTZ1 MGST1 MGST2 MGST3 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 hsa00982 Drug metabolism - cytochrome P450 ADH1A ADH1B ADH1C ADH4 ADH5 ADH6 ADH7 ALDH1A3 ALDH3A1 ALDH3B1 ALDH3B2 AOX1 CYP1A2 CYP2A13 CYP2A6 CYP2A7 CYP2B6 CYP2C18 CYP2C19 CYP2C8 CYP2C9 CYP2D6 CYP2E1 CYP3A4 CYP3A43 CYP3A5 CYP3A7 FMO1 FMO2 FMO3 FMO4 FMO5 GSTA1 GSTA2 GSTA3 GSTA4 GSTA5 GSTK1 GSTM1 GSTM2 GSTM3 GSTM4 GSTM5 GSTO1 GSTO2 GSTP1 GSTT1 GSTT2 GSTZ1 MAOA MAOB MGST1 MGST2 MGST3 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 hsa00983 Drug metabolism - other enzymes CDA CES1 CES2 CES5A CYP2A13 CYP2A6 CYP2A7 CYP3A4 CYP3A43 CYP3A5 CYP3A7 DPYD DPYS GMPS GUSB HPRT1 IMPDH1 IMPDH2 ITPA NAT1 NAT2 TK1 TK2 TPMT TYMP UCK1 UCK2 UCKL1 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UMPS UPB1 UPP1 UPP2 XDH hsa01040 Biosynthesis of unsaturated fatty acids ACAA1 ACOT1 ACOT2 ACOT4 ACOT7 ACOX1 ACOX3 BAAT ELOVL2 ELOVL5 ELOVL6 FADS1 FADS2 HADHA HSD17B12 PECR PTPLA PTPLB SCD SCD5 TECR hsa01100 Metabolic pathways 100133737 100289720 A4GALT AADAT AANAT AASDH AASDHPPT AASS ABAT ABO ACAA1 ACAA2 ACACA ACACB ACAD8 ACADL ACADM ACADS ACADSB ACADVL ACAT1 ACAT2 ACER1 ACER2 ACLY ACMSD ACO1 ACO2 ACOX1 ACOX2 ACOX3 ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 ACSM1 ACSM2A ACSM2B ACSM3 ACSM4 ACSM5 ACSS1 ACSS2 ACSS3 ACY1 ADA ADC ADH1A ADH1B ADH1C ADH4 ADH5 ADH6 ADH7 ADI1 ADK ADO ADPGK ADSL ADSS ADSSL1 AFMID AGK AGMAT AGPAT1 AGPAT2 AGPAT3 AGPAT4 AGPAT6 AGPAT9 AGPS AGXT AHCY AHCYL1 AHCYL2 AK1 AK2 AK4 AK5 AK7 AKR1A1 AKR1B1 AKR1B10 AKR1C4 AKR1D1 ALAD ALAS1 ALAS2 ALDH18A1 ALDH1A1 ALDH1A2 ALDH1A3 ALDH1B1 ALDH2 ALDH3A1 ALDH3A2 ALDH3B1 ALDH3B2 ALDH4A1 ALDH5A1 ALDH6A1 ALDH7A1 ALDH9A1 ALDOA ALDOB ALDOC ALG1 ALG10 ALG10B ALG11 ALG12 ALG13 ALG14 ALG2 ALG3 ALG5 ALG6 ALG8 ALG9 ALLC ALOX12 ALOX12B ALOX15 ALOX15B ALOX5 ALPI ALPL ALPP ALPPL2 AMACR AMD1 AMDHD1 AMPD1 AMPD2 AMPD3 AMT AMY1A AMY1B AMY1C AMY2A AMY2B ANPEP AOC2 AOC3 AOX1 APIP APRT ARG1 ARG2 ARSB ASAH1 ASAH2 ASAH2C ASL ASMT ASNS ASS1 ATIC ATP5A1 ATP5B ATP5C1 ATP5D ATP5E ATP5F1 ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5I ATP5J ATP5J2 ATP5L ATP5O ATP6 ATP6AP1 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H ATP8 AUH B3GALNT1 B3GALT1 B3GALT2 B3GALT4 B3GALT5 B3GALT6 B3GAT1 B3GAT2 B3GAT3 B3GNT1 B3GNT2 B3GNT3 B3GNT4 B3GNT5 B3GNT6 B4GALNT1 B4GALT1 B4GALT2 B4GALT3 B4GALT4 B4GALT6 B4GALT7 BAAT BCAT1 BCAT2 BCKDHA BCKDHB BCMO1 BDH1 BDH2 BHMT BPGM BPNT1 BST1 BTD C1GALT1 C1GALT1C1 CAD CAT CBR1 CBR3 CBS CD38 CDA CDIPT CDO1 CDS1 CDS2 CEL CEPT1 CES1 CES5A CHKA CHKB CHPF CHPF2 CHPT1 CHSY1 CHSY3 CKB CKM CKMT1A CKMT1B CKMT2 CMAS CMBL CMPK1 CMPK2 CNDP1 COASY COMT COQ2 COQ3 COQ5 COQ6 COQ7 COX1 COX10 COX11 COX15 COX17 COX2 COX3 COX4I1 COX4I2 COX5A COX5B COX6A1 COX6A2 COX6B1 COX6B2 COX6C COX7B COX7B2 COX7C COX8A COX8C CPOX CPS1 CRLS1 CRYL1 CS CSAD CSGALNACT1 CSGALNACT2 CTH CTPS CTPS2 CYC1 CYP11A1 CYP11B1 CYP11B2 CYP17A1 CYP19A1 CYP1A2 CYP21A2 CYP27A1 CYP27B1 CYP2A13 CYP2A6 CYP2A7 CYP2B6 CYP2C18 CYP2C19 CYP2C8 CYP2C9 CYP2E1 CYP2J2 CYP2U1 CYP3A4 CYP3A43 CYP3A5 CYP3A7 CYP4A11 CYP4A22 CYP4F2 CYP4F3 CYP51A1 CYP7A1 CYP8B1 CYTB DAD1 DAK DAO DBH DBT DCT DCTD DCXR DDC DDOST DEGS1 DEGS2 DGAT1 DGAT2 DGKA DGKB DGKD DGKE DGKG DGKH DGKI DGKQ DGKZ DGUOK DHCR24 DHCR7 DHFR DHODH DHRS3 DHRS4 DHRS4L2 DHRS9 DLAT DLD DLST DMGDH DNMT1 DNMT3A DNMT3B DNMT3L DOLK DPAGT1 DPM1 DPM2 DPM3 DPYD DPYS DTYMK DUT EARS2 EBP ECHS1 EHHADH ENO1 ENO2 ENO3 ENPP1 ENPP3 ENPP7 EPHX2 EPRS EPT1 ETNK1 ETNK2 EXT1 EXT2 EXTL1 EXTL3 FAH FASN FBP1 FBP2 FDFT1 FDPS FECH FH FLAD1 FPGS FPGT FUK FUT1 FUT2 FUT3 FUT4 FUT5 FUT6 FUT8 FUT9 G6PC G6PC2 G6PD GAA GAD1 GAD2 GAL3ST1 GALC GALE GALK1 GALK2 GALNS GALNT1 GALNT10 GALNT11 GALNT12 GALNT13 GALNT14 GALNT2 GALNT3 GALNT4 GALNT5 GALNT6 GALNT7 GALNT8 GALNT9 GALNTL1 GALNTL2 GALNTL4 GALNTL5 GALNTL6 GALT GAMT GANAB GANC GAPDH GAPDHS GART GATM GBA GBE1 GBGT1 GCDH GCH1 GCK GCLC GCLM GCNT1 GCNT2 GCNT3 GCNT4 GDA GFPT1 GFPT2 GGPS1 GGT1 GGT5 GGT6 GGT7 GK GK2 GLB1 GLCE GLDC GLS GLS2 GLUD1 GLUD2 GLUL GLYCTK GMDS GMPPA GMPPB GMPS GNE GNPDA1 GNPDA2 GNS GOT1 GOT2 GPAA1 GPAM GPAT2 GPI GPT GPT2 GRHPR GSS GSTZ1 GUK1 GUSB H6PD HAAO HADH HADHA HADHB HAL HAO1 HAO2 HDC HEXA HEXB HGD HGSNAT HIBADH HIBCH HK1 HK2 HK3 HLCS HMBS HMGCL HMGCR HMGCS1 HMGCS2 HPD HPGDS HPRT1 HPSE HPSE2 HSD11B1 HSD11B2 HSD17B1 HSD17B10 HSD17B12 HSD17B2 HSD17B3 HSD17B4 HSD17B6 HSD17B7 HSD17B8 HSD3B1 HSD3B2 HSD3B7 HYAL1 HYAL2 HYAL3 HYAL4 HYI IDH1 IDH2 IDH3A IDH3B IDH3G IDI1 IDI2 IDO1 IDO2 IDS IDUA IL4I1 IMPA1 IMPA2 IMPDH1 IMPDH2 INPP1 INPP4A INPP4B INPP5A INPP5B INPP5E INPP5J INPP5K INPPL1 IPPK ISYNA1 ITPA ITPK1 ITPKA ITPKB IVD JMJD7-PLA2G4B KDSR KHK KMO KYNU LALBA LAP3 LCLAT1 LCT LDHA LDHAL6A LDHAL6B LDHB LDHC LIAS LIPC LIPF LIPG LIPT1 LIPT2 LOC100130247 LOC100288842 LOC283398 LOC390424 LOC644310 LOC727947 LOC729020 LPCAT1 LPCAT2 LPCAT4 LSS LTA4H LTC4S MAN1A1 MAN1A2 MAN1B1 MAN1C1 MAN2A1 MAN2A2 MAOA MAOB MAT1A MAT2A MAT2B MBOAT1 MBOAT2 MCAT MCCC1 MCCC2 MCEE MDH1 MDH2 ME1 ME3 MECR MGAM MGAT1 MGAT2 MGAT3 MGAT4A MGAT4B MGAT5 MGAT5B MGLL MLYCD MMAB MOGS MPI MPST MTAP MTHFD1 MTHFD1L MTHFD2 MTHFD2L MTHFR MTHFS MTMR1 MTMR2 MTMR6 MTMR7 MTR MUT MVD MVK NADK NADSYN1 NAGLU NAGS NANP NANS NAT1 NAT2 ND1 ND2 ND3 ND4 ND4L ND5 ND6 NDST1 NDST2 NDST3 NDST4 NDUFA1 NDUFA10 NDUFA11 NDUFA2 NDUFA3 NDUFA4 NDUFA4L2 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFB1 NDUFB10 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 NME1 NME1-NME2 NME2 NME3 NME4 NME5 NME6 NME7 NMNAT1 NMNAT2 NMNAT3 NNMT NNT NOS1 NOS2 NOS3 NSDHL NT5C NT5C1A NT5C1B NT5C2 NT5C3 NT5E NT5M OAT OCRL ODC1 OGDH OGDHL OLAH OTC OXSM P4HA1 P4HA2 P4HA3 PAFAH1B1 PAFAH1B2 PAFAH1B3 PAFAH2 PAH PAICS PANK1 PANK2 PANK3 PANK4 PAPSS1 PAPSS2 PC PCCA PCCB PCK1 PCK2 PCYT1A PCYT1B PCYT2 PDHA1 PDHA2 PDHB PDHX PDXK PDXP PEMT PFAS PFKL PFKM PFKP PGAM1 PGAM2 PGAM4 PGAP1 PGD PGK1 PGK2 PGLS PGM1 PGM2 PGP PGS1 PHGDH PHOSPHO2 PHPT1 PI4K2A PI4K2B PI4KA PI4KB PIGA PIGB PIGC PIGF PIGH PIGK PIGL PIGM PIGN PIGO PIGP PIGQ PIGS PIGT PIGU PIGV PIGW PIGX PIGY PIK3C2A PIK3C2B PIK3C2G PIK3C3 PIP5K1A PIP5K1B PIP5K1C PIP5KL1 PIPOX PISD PKLR PKM2 PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PLA2G7 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLD1 PLD2 PMM1 PMM2 PMVK PNLIP PNLIPRP1 PNLIPRP2 PNMT PNP PNPLA3 PNPO POLA1 POLA2 POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLG POLG2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J2 POLR2J3 POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3F POLR3G POLR3GL POLR3H POLR3K PON1 PON2 PON3 PPAP2A PPAP2B PPAP2C PPAT PPCDC PPCS PPOX PPT1 PPT2 PRDX6 PRHOXNB PRIM1 PRIM2 PRODH PRODH2 PRPS1 PRPS1L1 PRPS2 PSAT1 PSPH PTDSS1 PTDSS2 PTGDS PTGES PTGES2 PTGIS PTGS1 PTS PYCR1 PYCR2 PYCRL QARS QDPR QPRT RDH10 RDH11 RDH12 RDH16 RDH8 REV3L RFK RPE RPIA RPN1 RPN2 RRM1 RRM2 RRM2B SARDH SAT1 SAT2 SC4MOL SC5DL SCLY SCP2 SDHA SDHB SDHC SDHD SDS SEPHS1 SEPHS2 SGMS1 SGMS2 SGPL1 SGSH SHMT1 SHMT2 SI SLC27A5 SLC33A1 SMPD1 SMPD2 SMPD3 SMPD4 SMS SORD SPAM1 SPHK1 SPHK2 SPR SPTLC1 SPTLC2 SQLE SRM ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL1 ST6GALNAC1 ST6GALNAC3 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA5 STT3A STT3B SUCLA2 SUCLG1 SUCLG2 SYNJ1 SYNJ2 TALDO1 TAT TBXAS1 TCIRG1 TDO2 TGDS TH THTPA TK1 TK2 TKT TKTL1 TKTL2 TM7SF2 TPH1 TPH2 TPI1 TPK1 TPO TRDMT1 TRIT1 TSTA3 TUSC3 TYMP TYMS TYR TYRP1 UAP1 UAP1L1 UCK1 UCK2 UCKL1 UGCG UGDH UGP2 UGT1A1 UGT1A10 UGT1A3 UGT1A4 UGT1A5 UGT1A6 UGT1A7 UGT1A8 UGT1A9 UGT2A1 UGT2A2 UGT2A3 UGT2B10 UGT2B11 UGT2B15 UGT2B17 UGT2B28 UGT2B4 UGT2B7 UGT8 UMPS UPB1 UPP1 UPP2 UPRT UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRHL UQCRQ UROC1 UROS UXS1 WBSCR17 XDH XYLB XYLT1 XYLT2 ZNRD1 hsa02010 ABC transporters ABCA1 ABCA10 ABCA12 ABCA13 ABCA2 ABCA3 ABCA4 ABCA5 ABCA6 ABCA7 ABCA8 ABCA9 ABCB1 ABCB10 ABCB11 ABCB4 ABCB5 ABCB6 ABCB7 ABCB8 ABCB9 ABCC1 ABCC10 ABCC11 ABCC12 ABCC2 ABCC3 ABCC4 ABCC5 ABCC6 ABCC8 ABCC9 ABCD1 ABCD2 ABCD3 ABCD4 ABCG1 ABCG2 ABCG4 ABCG5 ABCG8 CFTR TAP1 TAP2 hsa03010 Ribosome FAU MRPL13 RPL10 RPL10A RPL10L RPL11 RPL12 RPL13 RPL13A RPL14 RPL15 RPL17 RPL18 RPL18A RPL19 RPL21 RPL22 RPL22L1 RPL23 RPL23A RPL24 RPL26 RPL26L1 RPL27 RPL27A RPL28 RPL29 RPL3 RPL30 RPL31 RPL32 RPL34 RPL35 RPL35A RPL36 RPL36A RPL36AL RPL37 RPL37A RPL38 RPL39 RPL3L RPL4 RPL41 RPL5 RPL6 RPL7 RPL7A RPL8 RPL9 RPLP0 RPLP1 RPLP2 RPS10 RPS11 RPS12 RPS13 RPS15 RPS15A RPS16 RPS17 RPS18 RPS19 RPS2 RPS20 RPS21 RPS23 RPS24 RPS25 RPS26 RPS27 RPS27A RPS27L RPS28 RPS29 RPS3 RPS3A RPS4X RPS4Y1 RPS5 RPS6 RPS7 RPS8 RPS9 RPSA RSL24D1 RSL24D1P11 UBA52 hsa03018 RNA degradation C1D C1DP2 C1DP3 CNOT1 CNOT10 CNOT2 CNOT3 CNOT4 CNOT6 CNOT6L CNOT7 CNOT8 DCP1A DCP1B DCP2 DCPS DDX6 DIS3 EDC3 EDC4 ENO1 ENO2 ENO3 EXOSC1 EXOSC10 EXOSC2 EXOSC3 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 HSPA9 HSPD1 LSM1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPHOSPH6 NAA38 PAPD7 PAPOLA PAPOLB PAPOLG PARN PATL1 PNPT1 RQCD1 SKIV2L SKIV2L2 TTC37 WDR61 XRN1 XRN2 ZCCHC7 hsa03020 RNA polymerase POLR1A POLR1B POLR1C POLR1D POLR1E POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J2 POLR2J3 POLR2K POLR2L POLR3A POLR3B POLR3C POLR3D POLR3F POLR3G POLR3GL POLR3H POLR3K ZNRD1 hsa03022 Basal transcription factors GTF2A1 GTF2A1L GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2I GTF2IRD1 LOC391764 STON1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF1L TAF2 TAF4 TAF4B TAF5 TAF5L TAF6 TAF6L TAF7 TAF7L TAF9 TAF9B TBP TBPL1 TBPL2 hsa03030 DNA replication DNA2 FEN1 LIG1 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 PCNA POLA1 POLA2 POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 PRIM1 PRIM2 RFC1 RFC2 RFC3 RFC4 RFC5 RNASEH1 RNASEH2A RNASEH2B RNASEH2C RPA1 RPA2 RPA3 RPA4 SSBP1 hsa03040 Spliceosome ACIN1 AQR BAT1 BCAS2 BUD31 CCDC12 CDC40 CDC5L CHERP CRNKL1 CTNNBL1 CWC15 DDX23 DDX42 DDX46 DDX5 DHX15 DHX16 DHX38 DHX8 EFTUD2 EIF4A3 HNRNPA1 HNRNPA1L2 HNRNPA3 HNRNPC HNRNPK HNRNPM HNRNPU HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8 ISY1 LOC120364 LOC653884 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MAGOH MAGOHB NAA38 NCBP1 NCBP2 NHP2L1 PCBP1 PHF5A PLRG1 PPIE PPIH PPIL1 PQBP1 PRPF18 PRPF19 PRPF3 PRPF31 PRPF38A PRPF38B PRPF4 PRPF40A PRPF40B PRPF6 PRPF8 PUF60 RBM17 RBM22 RBM25 RBM8A RBMX SART1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B14 SF3B2 SF3B3 SF3B4 SF3B5 SLU7 SMNDC1 SNRNP200 SNRNP27 SNRNP40 SNRNP70 SNRPA SNRPA1 SNRPB SNRPB2 SNRPC SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNW1 SR140 SRSF1 SRSF10 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SRSF9 SYF2 TCERG1 THOC1 THOC2 THOC3 THOC4 TRA2A TRA2B TXNL4A U2AF1 U2AF2 USP39 WBP11 XAB2 ZMAT2 hsa03050 Proteasome IFNG LOC100132108 LOC121906 LOC345645 LOC652826 POMP PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB11 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSME1 PSME2 PSME3 PSME4 PSMF1 SHFM1 hsa03060 Protein export HSPA5 IMMP1L IMMP2L OXA1L SEC11A SEC11C SEC61A1 SEC61A2 SEC61B SEC61G SEC62 SEC63 SPCS1 SPCS2 SPCS3 SRP14 SRP19 SRP54 SRP68 SRP72 SRP9 SRP9P1 SRPR SRPRB hsa03320 PPAR signaling pathway ACAA1 ACADL ACADM ACOX1 ACOX2 ACOX3 ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 ADIPOQ ANGPTL4 APOA1 APOA2 APOA5 APOC3 AQP7 CD36 CPT1A CPT1B CPT1C CPT2 CYP27A1 CYP4A11 CYP4A22 CYP7A1 CYP8B1 DBI EHHADH FABP1 FABP2 FABP3 FABP4 FABP5 FABP6 FABP7 FADS2 GK GK2 HMGCS2 ILK LPL ME1 MMP1 NR1H3 OLR1 PCK1 PCK2 PDPK1 PLIN1 PLTP PPARA PPARD PPARG RXRA RXRB RXRG SCD SCD5 SCP2 SLC27A1 SLC27A2 SLC27A4 SLC27A5 SLC27A6 SORBS1 UBC UCP1 hsa03410 Base excision repair 645490 APEX1 APEX2 FEN1 HMGB1 LIG1 LIG3 MBD4 MPG MUTYH NEIL1 NEIL2 NEIL3 NTHL1 OGG1 PARP1 PARP2 PARP3 PARP4 PCNA POLB POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 POLL SMUG1 TDG UNG XRCC1 hsa03420 Nucleotide excision repair CCNH CDK7 CETN2 CUL4A CUL4B DDB1 DDB2 ERCC1 ERCC2 ERCC3 ERCC4 ERCC5 ERCC6 ERCC8 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 LIG1 MNAT1 PCNA POLD1 POLD2 POLD3 POLD4 POLE POLE2 POLE3 POLE4 RAD23A RAD23B RBX1 RFC1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RPA4 XPA XPC hsa03430 Mismatch repair EXO1 LIG1 MLH1 MLH3 MSH2 MSH3 MSH6 PCNA PMS2 POLD1 POLD2 POLD3 POLD4 RFC1 RFC2 RFC3 RFC4 RFC5 RPA1 RPA2 RPA3 RPA4 SSBP1 hsa03440 Homologous recombination BLM BRCA2 EME1 MRE11A MUS81 NBN POLD1 POLD2 POLD3 POLD4 RAD50 RAD51 RAD51C RAD51L1 RAD51L3 RAD52 RAD54B RAD54L RPA1 RPA2 RPA3 RPA4 SHFM1 SSBP1 TOP3A TOP3B XRCC2 XRCC3 hsa03450 Non-homologous end-joining DCLRE1C DNTT FEN1 LIG4 LOC731751 MRE11A NHEJ1 POLL POLM PRKDC RAD50 XRCC4 XRCC5 XRCC6 hsa04010 MAPK signaling pathway AKT1 AKT2 AKT3 ARRB1 ARRB2 ATF2 ATF4 BDNF BRAF CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CASP3 CD14 CDC25B CDC42 CHP CHP2 CHUK CRK CRKL DAXX DDIT3 DUSP1 DUSP10 DUSP14 DUSP16 DUSP2 DUSP3 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 ECSIT EGF EGFR ELK1 ELK4 FAS FASLG FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FLNA FLNB FLNC FOS GADD45A GADD45B GADD45G GNA12 GNG12 GRB2 HRAS HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8 HSPB1 IKBKB IKBKG IL1A IL1B IL1R1 IL1R2 JMJD7-PLA2G4B JUN JUND KRAS MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP2K7 MAP3K1 MAP3K11 MAP3K12 MAP3K13 MAP3K14 MAP3K2 MAP3K3 MAP3K4 MAP3K5 MAP3K6 MAP3K7 MAP3K8 MAP4K1 MAP4K2 MAP4K3 MAP4K4 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK7 MAPK8 MAPK8IP1 MAPK8IP2 MAPK8IP3 MAPK9 MAPKAPK2 MAPKAPK3 MAPKAPK5 MAPKSP1 MAPT MAX MECOM MEF2C MKNK1 MKNK2 MOS MRAS MYC NF1 NFATC2 NFATC4 NFKB1 NFKB2 NGF NLK NR4A1 NRAS NTF3 NTF4 NTRK1 NTRK2 PAK1 PAK2 PDGFA PDGFB PDGFRA PDGFRB PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PPM1A PPM1B PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PPP5C PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKX PTPN5 PTPN7 PTPRR RAC1 RAC2 RAC3 RAF1 RAP1A RAP1B RAPGEF2 RASA1 RASA2 RASGRF1 RASGRF2 RASGRP1 RASGRP2 RASGRP3 RASGRP4 RELA RELB RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 RRAS RRAS2 SOS1 SOS2 SRF STK3 STK4 STMN1 TAB1 TAB2 TAOK1 TAOK2 TAOK3 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TNF TNFRSF1A TP53 TRAF2 TRAF6 ZAK hsa04012 ErbB signaling pathway ABL1 ABL2 AKT1 AKT2 AKT3 ARAF AREG BAD BRAF BTC CAMK2A CAMK2B CAMK2D CAMK2G CBL CBLB CBLC CDKN1A CDKN1B CRK CRKL EGF EGFR EIF4EBP1 ELK1 ERBB2 ERBB3 ERBB4 EREG GAB1 GRB2 GSK3B HBEGF HRAS JUN KRAS MAP2K1 MAP2K2 MAP2K4 MAP2K7 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MTOR MYC NCK1 NCK2 NRAS NRG1 NRG2 NRG3 NRG4 PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCG1 PLCG2 PRKCA PRKCB PRKCG PTK2 RAF1 RPS6KB1 RPS6KB2 SHC1 SHC2 SHC3 SHC4 SOS1 SOS2 SRC STAT5A STAT5B TGFA hsa04020 Calcium signaling pathway ADCY1 ADCY2 ADCY3 ADCY4 ADCY7 ADCY8 ADCY9 ADORA2A ADORA2B ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 AGTR1 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 AVPR1A AVPR1B BDKRB1 BDKRB2 BST1 CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CACNA1G CACNA1H CACNA1I CACNA1S CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMK2A CAMK2B CAMK2D CAMK2G CAMK4 CCKAR CCKBR CD38 CHP CHP2 CHRM1 CHRM2 CHRM3 CHRM5 CHRNA7 CYSLTR1 CYSLTR2 DRD1 DRD5 EDNRA EDNRB EGFR ERBB2 ERBB3 ERBB4 F2R GNA11 GNA14 GNA15 GNAL GNAQ GNAS GRIN1 GRIN2A GRIN2C GRIN2D GRM1 GRM5 GRPR HRH1 HRH2 HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 ITPKA ITPKB ITPR1 ITPR2 ITPR3 LHCGR LOC729317 LTB4R2 MYLK MYLK2 MYLK3 NOS1 NOS2 NOS3 NTSR1 OXTR P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 PDE1A PDE1B PDE1C PDGFRA PDGFRB PHKA1 PHKA2 PHKB PHKG1 PHKG2 PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PLN PPID PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKX PTAFR PTGER1 PTGER3 PTGFR PTK2B RYR1 RYR2 RYR3 SLC25A31 SLC25A4 SLC25A5 SLC25A6 SLC8A1 SLC8A2 SLC8A3 SPHK1 SPHK2 TACR1 TACR2 TACR3 TBXA2R TNNC1 TNNC2 TRHR TRPC1 VDAC1 VDAC2 VDAC3 hsa04060 Cytokine-cytokine receptor interaction 652799 ACVR1 ACVR1B ACVR2A ACVR2B AMH AMHR2 BMP2 BMP7 BMPR1A BMPR1B BMPR2 CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL3L3 CCL4 CCL4L1 CCL4L2 CCL5 CCL7 CCL8 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CD27 CD40 CD40LG CD70 CLCF1 CNTF CNTFR CRLF2 CSF1 CSF1R CSF2 CSF2RA CSF2RB CSF3 CSF3R CTF1 CX3CL1 CX3CR1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 EDA EDA2R EDAR EGF EGFR EPO EPOR FAS FASLG FIGF FLT1 FLT3 FLT3LG FLT4 GDF5 GH1 GH2 GHR HGF IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR1 IFNAR2 IFNB1 IFNE IFNG IFNGR1 IFNGR2 IFNK IFNW1 IL10 IL10RA IL10RB IL11 IL11RA IL12A IL12B IL12RB1 IL12RB2 IL13 IL13RA1 IL15 IL15RA IL17A IL17B IL17RA IL17RB IL18 IL18R1 IL18RAP IL19 IL1A IL1B IL1R1 IL1R2 IL1RAP IL2 IL20 IL20RA IL20RB IL21 IL21R IL22 IL22RA1 IL22RA2 IL23A IL23R IL24 IL25 IL26 IL28A IL28B IL28RA IL29 IL2RA IL2RB IL2RG IL3 IL3RA IL4 IL4R IL5 IL5RA IL6 IL6R IL6ST IL7 IL7R IL8 IL9 IL9R INHBA INHBB INHBC INHBE KDR KIT KITLG LEP LEPR LIF LIFR LTA LTB LTBR MET MPL NGFR OSM OSMR PDGFA PDGFB PDGFC PDGFRA PDGFRB PF4 PF4V1 PLEKHO2 PPBP PRL PRLR RELT TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TNF TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF11A TNFRSF11B TNFRSF12A TNFRSF13B TNFRSF13C TNFRSF14 TNFRSF17 TNFRSF18 TNFRSF19 TNFRSF1A TNFRSF1B TNFRSF21 TNFRSF25 TNFRSF4 TNFRSF6B TNFRSF8 TNFRSF9 TNFSF10 TNFSF11 TNFSF12 TNFSF13 TNFSF13B TNFSF14 TNFSF15 TNFSF18 TNFSF4 TNFSF8 TNFSF9 TPO TSLP VEGFA VEGFB VEGFC XCL1 XCL2 XCR1 hsa04062 Chemokine signaling pathway ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRBK1 ADRBK2 AKT1 AKT2 AKT3 ARRB1 ARRB2 BCAR1 BRAF CCL1 CCL11 CCL13 CCL14 CCL15 CCL16 CCL17 CCL18 CCL19 CCL2 CCL20 CCL21 CCL22 CCL23 CCL24 CCL25 CCL26 CCL27 CCL28 CCL3 CCL3L1 CCL3L3 CCL4 CCL4L1 CCL4L2 CCL5 CCL7 CCL8 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CDC42 CHUK CRK CRKL CSK CX3CL1 CX3CR1 CXCL1 CXCL10 CXCL11 CXCL12 CXCL13 CXCL14 CXCL16 CXCL2 CXCL3 CXCL5 CXCL6 CXCL9 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 DOCK2 ELMO1 FGR FOXO3 GNAI1 GNAI2 GNAI3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 GRB2 GRK1 GRK4 GRK5 GRK6 GRK7 GSK3A GSK3B HCK HRAS IKBKB IKBKG IL8 ITK JAK2 JAK3 KRAS LYN MAP2K1 MAPK1 MAPK3 NCF1 NFKB1 NFKBIA NFKBIB NRAS PAK1 PARD3 PF4 PF4V1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCB1 PLCB2 PLCB3 PLCB4 PPBP PREX1 PRKACA PRKACB PRKACG PRKCB PRKCD PRKCZ PRKX PTK2 PTK2B PXN RAC1 RAC2 RAF1 RAP1A RAP1B RASGRP2 RELA RHOA ROCK1 ROCK2 SHC1 SHC2 SHC3 SHC4 SOS1 SOS2 STAT1 STAT2 STAT3 STAT5B TIAM1 TIAM2 VAV1 VAV2 VAV3 WAS WASL XCL1 XCL2 XCR1 hsa04070 Phosphatidylinositol signaling system CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CDIPT CDS1 CDS2 DGKA DGKB DGKD DGKE DGKG DGKH DGKI DGKQ DGKZ IMPA1 IMPA2 INPP1 INPP4A INPP4B INPP5A INPP5B INPP5D INPP5E INPP5J INPP5K INPPL1 IPPK ITPK1 ITPKA ITPKB ITPR1 ITPR2 ITPR3 OCRL PI4K2A PI4K2B PI4KA PI4KB PIK3C2A PIK3C2B PIK3C2G PIK3C3 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIKFYVE PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PLCB1 PLCB2 PLCB3 PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2 PLCZ1 PRKCA PRKCB PRKCG PTEN SYNJ1 SYNJ2 hsa04080 Neuroactive ligand-receptor interaction ADCYAP1R1 ADORA1 ADORA2A ADORA2B ADORA3 ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 AGTR1 AGTR2 APLNR AVPR1A AVPR1B AVPR2 BDKRB1 BDKRB2 BRS3 C3AR1 C5AR1 CALCR CALCRL CCKAR CCKBR CGA CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CHRNA1 CHRNA10 CHRNA2 CHRNA3 CHRNA4 CHRNA5 CHRNA6 CHRNA7 CHRNA9 CHRNB1 CHRNB2 CHRNB3 CHRNB4 CHRND CHRNE CHRNG CNR1 CNR2 CRHR1 CRHR2 CSH1 CTSG CYSLTR1 CYSLTR2 DRD1 DRD2 DRD3 DRD4 DRD5 EDNRA EDNRB F2 F2R F2RL1 F2RL2 F2RL3 FPR1 FPR2 FPR3 FSHB FSHR GABBR1 GABBR2 GABRA1 GABRA2 GABRA3 GABRA4 GABRA5 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GABRE GABRG1 GABRG2 GABRG3 GABRP GABRQ GABRR1 GABRR2 GALR1 GALR2 GALR3 GCGR GH1 GH2 GHR GHRHR GHSR GIPR GLP1R GLP2R GLRA1 GLRA2 GLRA3 GLRB GNRHR GPR156 GPR35 GPR50 GPR83 GRIA1 GRIA2 GRIA3 GRIA4 GRID1 GRID2 GRIK1 GRIK2 GRIK3 GRIK4 GRIK5 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRIN3A GRIN3B GRM1 GRM2 GRM3 GRM4 GRM5 GRM6 GRM7 GRM8 GRPR GZMA HCRTR1 HCRTR2 HRH1 HRH2 HRH3 HRH4 HTR1A HTR1B HTR1D HTR1E HTR1F HTR2A HTR2B HTR2C HTR4 HTR5A HTR6 HTR7 KISS1R LEP LEPR LHB LHCGR LPAR1 LPAR2 LPAR3 LPAR4 LPAR6 LTB4R LTB4R2 MAS1 MC1R MC2R MC3R MC4R MC5R MCHR1 MCHR2 MLNR MTNR1A MTNR1B NMBR NMUR1 NMUR2 NPBWR1 NPBWR2 NPFFR1 NPFFR2 NPY1R NPY2R NPY5R NR3C1 NTSR1 NTSR2 OPRD1 OPRK1 OPRL1 OPRM1 OXTR P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 P2RY1 P2RY10 P2RY11 P2RY13 P2RY14 P2RY2 P2RY4 P2RY6 P2RY8 PARD3 PLG PPYR1 PRL PRLHR PRLR PRSS1 PRSS2 PRSS3 PTAFR PTGDR PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR PTH1R PTH2R RXFP1 RXFP2 S1PR1 S1PR2 S1PR3 S1PR4 S1PR5 SCTR SSTR1 SSTR2 SSTR3 SSTR4 SSTR5 TAAR1 TAAR2 TAAR5 TAAR6 TAAR8 TAAR9 TACR1 TACR2 TACR3 TBXA2R THRA THRB TRHR TRPV1 TSHB TSHR TSPO UTS2R VIPR1 VIPR2 hsa04110 Cell cycle ABL1 ANAPC1 ANAPC10 ANAPC11 ANAPC13 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ATM ATR BUB1 BUB1B BUB3 CCNA1 CCNA2 CCNB1 CCNB2 CCNB3 CCND1 CCND2 CCND3 CCNE1 CCNE2 CCNH CDC14A CDC14B CDC16 CDC20 CDC23 CDC25A CDC25B CDC25C CDC26 CDC27 CDC45 CDC6 CDC7 CDK1 CDK2 CDK4 CDK6 CDK7 CDKN1A CDKN1B CDKN1C CDKN2A CDKN2B CDKN2C CDKN2D CHEK1 CHEK2 CREBBP CUL1 DBF4 E2F1 E2F2 E2F3 E2F4 E2F5 EP300 ESPL1 FZR1 GADD45A GADD45B GADD45G GSK3B HDAC1 HDAC2 LOC650621 LOC651610 LOC728622 LOC731751 MAD1L1 MAD2L1 MAD2L2 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 MDM2 MYC ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PCNA PKMYT1 PLK1 PRKDC PTTG1 PTTG2 RAD21 RB1 RBL1 RBL2 RBX1 SFN SKP1 SKP2 SMAD2 SMAD3 SMAD4 SMC1A SMC1B SMC3 STAG1 STAG2 TFDP1 TFDP2 TGFB1 TGFB2 TGFB3 TP53 TTK WEE1 WEE2 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZBTB17 hsa04114 Oocyte meiosis ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ANAPC1 ANAPC10 ANAPC11 ANAPC13 ANAPC2 ANAPC4 ANAPC5 ANAPC7 AR AURKA BTRC BUB1 CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMK2A CAMK2B CAMK2D CAMK2G CCNB1 CCNB2 CCNE1 CCNE2 CDC16 CDC20 CDC23 CDC25C CDC26 CDC27 CDK1 CDK2 CHP CHP2 CPEB1 CUL1 ESPL1 FBXO43 FBXO5 FBXW11 IGF1 IGF1R INS ITPR1 ITPR2 ITPR3 LOC650621 LOC728622 MAD2L1 MAD2L2 MAP2K1 MAPK1 MAPK12 MAPK3 MOS PGR PKMYT1 PLCZ1 PLK1 PPP1CA PPP1CB PPP1CC PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKACA PRKACB PRKACG PRKX PTTG1 PTTG2 RBX1 REC8 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 SGOL1 SKP1 SLK SMC1A SMC1B SMC3 SPDYA SPDYC STAG3 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ hsa04115 p53 signaling pathway APAF1 ATM ATR BAI1 BAX BBC3 BID CASP3 CASP8 CASP9 CCNB1 CCNB2 CCNB3 CCND1 CCND2 CCND3 CCNE1 CCNE2 CCNG1 CCNG2 CD82 CDK1 CDK2 CDK4 CDK6 CDKN1A CDKN2A CHEK1 CHEK2 CYCS DDB2 EI24 FAS GADD45A GADD45B GADD45G GTSE1 IGF1 IGFBP3 LOC651610 LRDD MDM2 MDM4 PERP PMAIP1 PPM1D PTEN RCHY1 RFWD2 RPRM RRM2 RRM2B SERPINB5 SERPINE1 SESN1 SESN2 SESN3 SFN SHISA5 SIAH1 STEAP3 THBS1 TNFRSF10B TP53 TP53AIP1 TP53I3 TP73 TSC2 ZMAT3 hsa04120 Ubiquitin mediated proteolysis 652671 AIRE ANAPC1 ANAPC10 ANAPC11 ANAPC13 ANAPC2 ANAPC4 ANAPC5 ANAPC7 BIRC2 BIRC3 BIRC6 BRCA1 BTRC CBL CBLB CBLC CDC16 CDC20 CDC23 CDC26 CDC27 CDC34 CUL1 CUL2 CUL3 CUL4A CUL4B CUL5 CUL7 DDB1 DDB2 DET1 ERCC8 FANCL FBXO2 FBXO4 FBXW11 FBXW7 FBXW8 FZR1 HERC1 HERC2 HERC3 HERC4 HUWE1 ITCH KEAP1 KLHL13 KLHL9 LOC650621 LOC652346 LOC728622 MAP3K1 MDM2 MGRN1 MID1 NEDD4 NEDD4L NHLRC1 PARK2 PIAS1 PIAS2 PIAS3 PIAS4 PML PPIL2 PRPF19 RBX1 RCHY1 RFWD2 RHOBTB1 RHOBTB2 RNF7 SAE1 SIAH1 SKP1 SKP2 SMURF1 SMURF2 SOCS1 SOCS3 STUB1 SYVN1 TCEB1 TCEB2 TRAF6 TRIM32 TRIM37 TRIP12 UBA1 UBA2 UBA3 UBA6 UBA7 UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2F UBE2G1 UBE2G2 UBE2H UBE2I UBE2J1 UBE2J2 UBE2K UBE2L3 UBE2L6 UBE2M UBE2N UBE2NL UBE2O UBE2Q1 UBE2Q2 UBE2QL1 UBE2R2 UBE2S UBE2U UBE2W UBE2Z UBE3A UBE3B UBE3C UBE4A UBE4B UBOX5 UBR5 VHL WWP1 WWP2 XIAP hsa04130 SNARE interactions in vesicular transport BET1 BET1L BNIP1 GOSR1 GOSR2 SEC22B SNAP23 SNAP25 SNAP29 SNAP47 STX10 STX11 STX16 STX17 STX18 STX19 STX1A STX1B STX2 STX3 STX4 STX5 STX6 STX7 STX8 USE1 VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VAMP7 VAMP8 VTI1A VTI1B YKT6 hsa04140 Regulation of autophagy ATG12 ATG3 ATG4A ATG4B ATG4C ATG4D ATG5 ATG7 BECN1 BECN1P1 GABARAP GABARAPL1 GABARAPL2 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNG INS PIK3C3 PIK3R4 PRKAA1 PRKAA2 ULK1 ULK2 ULK3 hsa04141 Protein processing in endoplasmic reticulum AMFR ATF4 ATF6 ATF6B ATXN3 ATXN3L BAG1 BAG2 BAK1 BAX BCAP31 BCL2 CALR CANX CAPN1 CAPN2 CKAP4 CRYAA CRYAB CUL1 DAD1 DDIT3 DDOST DERL1 DERL2 DERL3 DNAJA1 DNAJA2 DNAJB1 DNAJB11 DNAJB12 DNAJB2 DNAJC1 DNAJC10 DNAJC3 DNAJC5 DNAJC5B DNAJC5G EDEM1 EDEM2 EDEM3 EIF2AK1 EIF2AK2 EIF2AK3 EIF2AK4 EIF2S1 ERLEC1 ERN1 ERO1L ERO1LB ERP29 FBXO2 FBXO6 GANAB HERPUD1 HSP90AA1 HSP90AB1 HSP90B1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA4L HSPA5 HSPA6 HSPA8 HSPBP1 HSPH1 HYOU1 LMAN1 LMAN1L LMAN2 LOC100289713 LOC728622 MAN1A1 MAN1A2 MAN1B1 MAN1C1 MAP2K7 MAP3K5 MAPK10 MAPK8 MAPK9 MARCH6 MBTPS1 MBTPS2 MOGS NFE2L2 NGLY1 NPLOC4 NSFL1C OS9 P4HB PARK2 PDIA3 PDIA4 PDIA6 PLAA PPP1R15A PREB PRKCSH RAD23A RAD23B RBX1 RNF5 RPN1 RPN2 RRBP1 SAR1A SAR1B SEC13 SEC23A SEC23B SEC24A SEC24B SEC24C SEC24D SEC31A SEC31B SEC61A1 SEC61A2 SEC61B SEC61G SEC62 SEC63 SEL1L SELS SIL1 SKP1 SSR1 SSR2 SSR3 SSR4 STT3A STT3B STUB1 SVIP SYVN1 TRAF2 TRAM1 TUSC3 TXNDC5 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2G2 UBE2J1 UBE2J2 UBE4B UBQLN1 UBQLN2 UBQLN3 UBQLN4 UBQLNL UBXN6 UFD1L UGGT1 UGGT2 VCP WFS1 XBP1 YOD1 hsa04142 Lysosome ABCA2 ABCB9 ACP2 ACP5 AGA AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP3B1 AP3B2 AP3D1 AP3M1 AP3M2 AP3S1 AP3S2 AP4B1 AP4E1 AP4M1 AP4S1 ARSA ARSB ARSG ASAH1 ATP6AP1 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V1H CD164 CD63 CD68 CLN3 CLN5 CLTA CLTB CLTC CLTCL1 CTNS CTSA CTSB CTSC CTSD CTSE CTSF CTSG CTSH CTSK CTSL1 CTSL2 CTSO CTSS CTSW CTSZ DNASE2 DNASE2B ENTPD4 FUCA1 GAA GALC GALNS GBA GGA1 GGA2 GGA3 GLA GLB1 GM2A GNPTAB GNPTG GNS GUSB HEXA HEXB HGSNAT HYAL1 IDS IDUA IGF2R LAMP1 LAMP2 LAMP3 LAPTM4A LAPTM4B LAPTM5 LGMN LIPA M6PR MAN2B1 MANBA MCOLN1 MFSD8 NAGA NAGLU NAGPA NAPSA NEU1 NPC1 NPC2 PLA2G15 PPT1 PPT2 PSAP PSAPL1 SCARB2 SGSH SLC11A1 SLC11A2 SLC17A5 SMPD1 SORT1 SUMF1 TCIRG1 TPP1 hsa04144 Endocytosis 652671 652799 ACAP1 ACAP2 ACAP3 ADRB1 ADRB2 ADRB3 ADRBK1 ADRBK2 AGAP1 AGAP2 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARAP1 ARAP2 ARAP3 ARF6 ARFGAP1 ARFGAP2 ARFGAP3 ARRB1 ARRB2 ASAP1 ASAP2 ASAP3 CAV1 CAV2 CAV3 CBL CBLB CBLC CCR5 CDC42 CHMP1B CHMP2A CHMP2B CHMP4A CHMP4B CHMP4C CHMP5 CHMP6 CLTA CLTB CLTC CLTCL1 CSF1R CXCR1 CXCR2 CXCR4 DAB2 DNAJC6 DNM1 DNM1L DNM2 DNM3 EEA1 EGF EGFR EHD1 EHD2 EHD3 EHD4 EPN1 EPN2 EPN3 EPS15 ERBB3 ERBB4 F2R FAM125A FAM125B FGFR2 FGFR3 FGFR4 FLT1 FOLR1 FOLR2 FOLR3 FOLR4 GIT1 GIT2 GRK1 GRK4 GRK5 GRK6 GRK7 HGS HLA-A HLA-B HLA-C HLA-E HLA-F HLA-G HRAS HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8 IGF1R IL2RA IL2RB IL2RG IQSEC1 IQSEC2 IQSEC3 ITCH KDR KIT LDLR LDLRAP1 LOC652346 LOC652614 MDM2 MET NEDD4 NEDD4L NTRK1 PARD3 PARD6A PARD6B PARD6G PDCD6IP PDGFRA PIP5K1A PIP5K1B PIP5K1C PIP5KL1 PLD1 PLD2 PML PRKCI PRKCZ PSD PSD2 PSD3 PSD4 RAB11A RAB11B RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB22A RAB31 RAB4A RAB5A RAB5B RAB5C RAB7A RABEP1 RET RHOA RNF41 RUFY1 SH3GL1 SH3GL2 SH3GL3 SH3GLB1 SH3GLB2 SH3KBP1 SMAD2 SMAD3 SMAD6 SMAD7 SMAP1 SMAP2 SMURF1 SMURF2 SNF8 SRC STAM STAM2 STAMBP TFRC TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TRAF6 TSG101 USP8 VPS24 VPS25 VPS28 VPS36 VPS37A VPS37B VPS37C VPS37D VPS45 VPS4A VPS4B VTA1 WWP1 ZFYVE16 ZFYVE20 ZFYVE9 hsa04145 Phagosome 100294318 646048 646821 ACTB ACTG1 ATP6AP1 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H C1R C3 CALR CANX CD14 CD209 CD36 CLEC4M CLEC7A COLEC11 COLEC12 COMP CORO1A CTSL1 CTSS CYBA CYBB DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNC2H1 EEA1 FCAR FCGR1A FCGR2A FCGR2B FCGR2C FCGR3A FCGR3B HGS HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-E HLA-F HLA-G ITGA2 ITGA5 ITGAM ITGAV ITGB1 ITGB2 ITGB3 ITGB5 LAMP1 LAMP2 LOC100133583 LOC652614 M6PR MARCO MBL2 MPO MRC1 MRC1L1 MRC2 MSR1 NCF1 NCF2 NCF4 NOS1 NOX1 NOX3 OLR1 PIK3C3 PIKFYVE PLA2R1 RAB5A RAB5B RAB5C RAB7A RAB7B RAC1 RILP SCARB1 SEC22B SEC61A1 SEC61A2 SEC61B SEC61G SFTPA1 SFTPD STX12 STX18 STX7 TAP1 TAP2 TCIRG1 TFRC THBS1 THBS2 THBS3 THBS4 TLR2 TLR4 TLR6 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA8 TUBAL3 TUBB TUBB1 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4Q TUBB6 TUBB8 VAMP3 hsa04146 Peroxisome ABCD1 ABCD2 ABCD3 ABCD4 ACAA1 ACOT8 ACOX1 ACOX2 ACOX3 ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 AGPS AGXT AMACR BAAT CAT CRAT CROT DAO DDO DECR2 DHRS4 ECH1 EHHADH EPHX2 FAR1 FAR2 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HSD17B4 IDH1 IDH2 MLYCD MPV17 MPV17L MVK NOS2 NUDT12 NUDT19 PAOX PECI PECR PEX1 PEX10 PEX11A PEX11B PEX11G PEX12 PEX13 PEX14 PEX16 PEX19 PEX2 PEX26 PEX3 PEX5 PEX6 PEX7 PHYH PIPOX PMVK PRDX1 PRDX5 PXMP2 PXMP4 SCP2 SLC25A17 SLC27A2 SOD1 SOD2 XDH hsa04150 mTOR signaling pathway AKT1 AKT2 AKT3 BRAF CAB39 CAB39L DDIT4 EIF4B EIF4E EIF4E1B EIF4E2 EIF4EBP1 FIGF HIF1A IGF1 INS MAPK1 MAPK3 MLST8 MTOR PDPK1 PGF PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PRKAA1 PRKAA2 RHEB RICTOR RPS6 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 RPS6KB1 RPS6KB2 RPTOR STK11 STRADA TSC1 TSC2 ULK1 ULK2 ULK3 VEGFA VEGFB VEGFC hsa04210 Apoptosis AIFM1 AKT1 AKT2 AKT3 APAF1 ATM BAD BAX BCL2 BCL2L1 BID BIRC2 BIRC3 CAPN1 CAPN2 CASP10 CASP3 CASP6 CASP7 CASP8 CASP9 CFLAR CHP CHP2 CHUK CSF2RB CYCS DFFA DFFB ENDOD1 ENDOG EXOG FADD FAS FASLG IKBKB IKBKG IL1A IL1B IL1R1 IL1RAP IL3 IL3RA IRAK1 IRAK2 IRAK3 IRAK4 LOC651610 MAP3K14 MYD88 NFKB1 NFKBIA NGF NTRK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKACA PRKACB PRKACG PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKX RELA RIPK1 TNF TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFRSF1A TNFSF10 TP53 TRADD TRAF2 XIAP hsa04260 Cardiac muscle contraction ACTC1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP1B4 ATP2A2 CACNA1C CACNA1D CACNA1F CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 COX1 COX2 COX3 COX4I1 COX4I2 COX5A COX5B COX6A1 COX6A2 COX6B1 COX6B2 COX6C COX7A1 COX7A2 COX7A2L COX7B COX7B2 COX7C COX8A COX8C CYC1 CYTB FXYD2 LOC100130247 LOC644310 LOC727947 MYH6 MYH7 MYL2 MYL3 RYR2 SLC8A1 SLC9A1 SLC9A6 TNNC1 TNNI3 TNNT2 TPM1 TPM2 TPM3 TPM4 UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRHL UQCRQ hsa04270 Vascular smooth muscle contraction ACTA2 ACTG2 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADORA2A ADORA2B ADRA1A ADRA1B ADRA1D AGTR1 ARAF ARHGEF1 ARHGEF11 ARHGEF12 AVPR1A AVPR1B BRAF CACNA1C CACNA1D CACNA1F CACNA1S CALCRL CALD1 CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CYP4A11 CYP4A22 EDNRA GNA11 GNA12 GNA13 GNAQ GNAS GUCY1A2 GUCY1A3 GUCY1B3 ITPR1 ITPR2 ITPR3 JMJD7-PLA2G4B KCNMA1 KCNMB1 KCNMB2 KCNMB3 KCNMB4 KCNU1 MAP2K1 MAP2K2 MAPK1 MAPK3 MRVI1 MYH11 MYL6 MYL6B MYL9 MYLK MYLK2 MYLK3 NPR1 NPR2 PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PLCB1 PLCB2 PLCB3 PLCB4 PPP1CA PPP1CB PPP1CC PPP1R12A PPP1R12B PPP1R14A PRKACA PRKACB PRKACG PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ PRKG1 PRKX PTGIR RAF1 RAMP1 RAMP2 RAMP3 RHOA ROCK1 ROCK2 hsa04310 Wnt signaling pathway APC APC2 AXIN1 AXIN2 BTRC CACYBP CAMK2A CAMK2B CAMK2D CAMK2G CCND1 CCND2 CCND3 CER1 CHD8 CHP CHP2 CREBBP CSNK1A1 CSNK1A1L CSNK1E CSNK2A1 CSNK2A2 CSNK2B CTBP1 CTBP2 CTNNB1 CTNNBIP1 CUL1 CXXC4 DAAM1 DAAM2 DKK1 DKK2 DKK4 DVL1 DVL2 DVL3 EP300 FBXW11 FOSL1 FRAT1 FRAT2 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GSK3B JUN LEF1 LOC728622 LRP5 LRP6 MAP3K7 MAPK10 MAPK8 MAPK9 MMP7 MYC NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NKD1 NKD2 NLK PLCB1 PLCB2 PLCB3 PLCB4 PORCN PPARD PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R5A PPP2R5B PPP2R5C PPP2R5D PPP2R5E PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRICKLE1 PRICKLE2 PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKX PSEN1 RAC1 RAC2 RAC3 RBX1 RHOA ROCK1 ROCK2 RUVBL1 SENP2 SFRP1 SFRP2 SFRP4 SFRP5 SIAH1 SKP1 SMAD2 SMAD3 SMAD4 SOX17 TBL1X TBL1XR1 TBL1Y TCF7 TCF7L1 TCF7L2 TP53 VANGL1 VANGL2 WIF1 WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B hsa04320 Dorso-ventral axis formation CPEB1 EGFR ETS1 ETS2 ETV6 ETV7 FMN2 GRB2 KRAS LOC652554 MAP2K1 MAPK1 MAPK3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PIWIL1 PIWIL2 PIWIL3 PIWIL4 SOS1 SOS2 SPIRE1 SPIRE2 hsa04330 Notch signaling pathway ADAM17 APH1A CIR1 CREBBP CTBP1 CTBP2 DLL1 DLL3 DLL4 DTX1 DTX2 DTX3 DTX3L DTX4 DVL1 DVL2 DVL3 EP300 HDAC1 HDAC2 HES1 HES5 JAG1 JAG2 KAT2A KAT2B LFNG MAML1 MAML2 MAML3 MFNG NCOR2 NCSTN NOTCH1 NOTCH2 NOTCH3 NOTCH4 NUMB NUMBL PSEN1 PSEN2 PSENEN PTCRA RBPJ RBPJL RFNG SNW1 hsa04340 Hedgehog signaling pathway BMP2 BMP4 BMP5 BMP6 BMP7 BMP8A BMP8B BTRC CSNK1A1 CSNK1A1L CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 DHH FBXW11 GAS1 GLI1 GLI2 GLI3 GSK3B HHIP IHH LRP2 PRKACA PRKACB PRKACG PRKX PTCH1 PTCH2 RAB23 SHH SMO STK36 SUFU WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B ZIC2 hsa04350 TGF-beta signaling pathway ACVR1 ACVR1C ACVR2A ACVR2B AMH AMHR2 BMP2 BMP4 BMP5 BMP6 BMP7 BMP8A BMP8B BMPR1A BMPR1B BMPR2 CDKN2B CHRD COMP CREBBP CUL1 DCN E2F4 E2F5 EP300 FST GDF5 GDF6 GDF7 ID1 ID2 ID3 ID4 IFNG INHBA INHBB INHBC INHBE LEFTY1 LEFTY2 LOC728622 LTBP1 MAPK1 MAPK3 MYC NODAL NOG PITX2 PPP2CA PPP2CB PPP2R1A PPP2R1B RBL1 RBL2 RBX1 RHOA ROCK1 ROCK2 RPS6KB1 RPS6KB2 SKP1 SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 SMURF1 SMURF2 SP1 TFDP1 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 THBS1 THBS2 THBS3 THBS4 TNF ZFYVE16 ZFYVE9 hsa04360 Axon guidance ABL1 ABLIM1 ABLIM2 ABLIM3 ARHGEF12 CDC42 CDK5 CFL1 CFL2 CHP CHP2 CXCL12 CXCR4 DCC DPYSL2 DPYSL5 EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EPHA1 EPHA2 EPHA3 EPHA4 EPHA5 EPHA6 EPHA7 EPHA8 EPHB1 EPHB2 EPHB3 EPHB4 EPHB6 FES FYN GNAI1 GNAI2 GNAI3 GSK3B HRAS ITGB1 KRAS L1CAM LIMK1 LIMK2 LRRC4C MAPK1 MAPK3 MET NCK1 NCK2 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NGEF NRAS NRP1 NTN1 NTN3 NTN4 NTNG1 PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PLXNA1 PLXNA2 PLXNA3 PLXNB1 PLXNB2 PLXNB3 PLXNC1 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PTK2 RAC1 RAC2 RAC3 RASA1 RGS3 RHOA RHOD RND1 ROBO1 ROBO2 ROBO3 ROCK1 ROCK2 SEMA3A SEMA3B SEMA3C SEMA3D SEMA3E SEMA3F SEMA3G SEMA4A SEMA4B SEMA4C SEMA4D SEMA4F SEMA4G SEMA5A SEMA5B SEMA6A SEMA6B SEMA6C SEMA6D SEMA7A SLIT1 SLIT2 SLIT3 SRGAP1 SRGAP2 SRGAP3 UNC5A UNC5B UNC5C UNC5D hsa04370 VEGF signaling pathway AKT1 AKT2 AKT3 BAD CASP9 CDC42 CHP CHP2 HRAS HSPB1 JMJD7-PLA2G4B KDR KRAS MAP2K1 MAP2K2 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPKAPK2 MAPKAPK3 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NOS3 NRAS PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PLCG1 PLCG2 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKCA PRKCB PRKCG PTGS2 PTK2 PXN RAC1 RAC2 RAC3 RAF1 SH2D2A SHC2 SPHK1 SPHK2 SRC VEGFA hsa04510 Focal adhesion 646048 646821 ACTB ACTG1 ACTN1 ACTN2 ACTN3 ACTN4 AKT1 AKT2 AKT3 ARHGAP5 BAD BCAR1 BCL2 BIRC2 BIRC3 BRAF CAPN2 CAV1 CAV2 CAV3 CCND1 CCND2 CCND3 CDC42 CHAD COL11A1 COL11A2 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A4 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL6A6 COMP CRK CRKL CTNNB1 DIAPH1 DOCK1 EGF EGFR ELK1 ERBB2 FIGF FLNA FLNB FLNC FLT1 FLT4 FN1 FYN GRB2 GRLF1 GSK3B HGF HRAS IBSP IGF1 IGF1R ILK ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUN KDR LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 MAP2K1 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MET MYL10 MYL12A MYL12B MYL2 MYL5 MYL7 MYL9 MYLK MYLK2 MYLK3 MYLPF PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PARVA PARVB PARVG PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PDPK1 PGF PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIP5K1C PPP1CA PPP1CB PPP1CC PPP1R12A PRKCA PRKCB PRKCG PTEN PTK2 PXN RAC1 RAC2 RAC3 RAF1 RAP1A RAP1B RAPGEF1 RASGRF1 RELN RHOA ROCK1 ROCK2 SHC1 SHC2 SHC3 SHC4 SOS1 SOS2 SPP1 SRC THBS1 THBS2 THBS3 THBS4 TLN1 TLN2 TNC TNN TNR TNXB VASP VAV1 VAV2 VAV3 VCL VEGFA VEGFB VEGFC VTN VWF XIAP ZYX hsa04512 ECM-receptor interaction AGRN CD36 CD44 CD47 CHAD COL11A1 COL11A2 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A4 COL4A6 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 COL6A6 COMP DAG1 FN1 GP1BA GP1BB GP5 GP6 GP9 HMMR HSPG2 IBSP ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 RELN SDC1 SDC2 SDC3 SDC4 SPP1 SV2A SV2B SV2C THBS1 THBS2 THBS3 THBS4 TNC TNN TNR TNXB VTN VWF hsa04514 Cell adhesion molecules (CAMs) 100294318 ALCAM CADM1 CADM3 CD2 CD22 CD226 CD274 CD276 CD28 CD34 CD4 CD40 CD40LG CD58 CD6 CD80 CD86 CD8A CD8B CD99 CDH1 CDH15 CDH2 CDH3 CDH4 CDH5 CLDN1 CLDN10 CLDN11 CLDN14 CLDN15 CLDN16 CLDN17 CLDN18 CLDN19 CLDN2 CLDN20 CLDN22 CLDN23 CLDN3 CLDN4 CLDN5 CLDN6 CLDN7 CLDN8 CLDN9 CNTN1 CNTN2 CNTNAP1 CNTNAP2 CTLA4 ESAM F11R GLG1 HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-E HLA-F HLA-G ICAM1 ICAM2 ICAM3 ICOS ICOSLG ITGA4 ITGA6 ITGA8 ITGA9 ITGAL ITGAM ITGAV ITGB1 ITGB2 ITGB7 ITGB8 JAM2 JAM3 L1CAM LOC100133583 LOC652614 MADCAM1 MAG MPZ MPZL1 NCAM1 NCAM2 NEGR1 NEO1 NFASC NLGN1 NLGN2 NLGN3 NLGN4X NRCAM NRXN1 NRXN2 NRXN3 OCLN PDCD1 PDCD1LG2 PECAM1 PTPRC PTPRF PTPRM PVR PVRL1 PVRL2 PVRL3 SDC1 SDC2 SDC3 SDC4 SELE SELL SELP SELPLG SIGLEC1 SPN VCAM1 VCAN hsa04520 Adherens junction 646048 646821 ACP1 ACTB ACTG1 ACTN1 ACTN2 ACTN3 ACTN4 BAIAP2 CDC42 CDH1 CREBBP CSNK2A1 CSNK2A2 CSNK2B CTNNA1 CTNNA2 CTNNA3 CTNNB1 CTNND1 EGFR EP300 ERBB2 FARP2 FER FGFR1 FYN IGF1R INSR IQGAP1 LEF1 LMO7 MAP3K7 MAPK1 MAPK3 MET MLLT4 NLK PARD3 PTPN1 PTPN6 PTPRB PTPRF PTPRJ PTPRM PVRL1 PVRL2 PVRL3 PVRL4 RAC1 RAC2 RAC3 RHOA SMAD2 SMAD3 SMAD4 SNAI1 SNAI2 SORBS1 SRC SSX2IP TCF7 TCF7L1 TCF7L2 TGFBR1 TGFBR2 TJP1 VCL WAS WASF1 WASF2 WASF3 WASL YES1 hsa04530 Tight junction 646048 646821 ACTB ACTG1 ACTN1 ACTN2 ACTN3 ACTN4 AKT1 AKT2 AKT3 AMOTL1 ASH1L CASK CDC42 CDK4 CGN CLDN1 CLDN10 CLDN11 CLDN14 CLDN15 CLDN16 CLDN17 CLDN18 CLDN19 CLDN2 CLDN20 CLDN22 CLDN23 CLDN3 CLDN4 CLDN5 CLDN6 CLDN7 CLDN8 CLDN9 CRB3 CSDA CSNK2A1 CSNK2A2 CSNK2B CTNNA1 CTNNA2 CTNNA3 CTNNB1 CTTN EPB41 EPB41L1 EPB41L2 EPB41L3 EXOC3 EXOC4 F11R GNAI1 GNAI2 GNAI3 HCLS1 HRAS IGSF5 INADL JAM2 JAM3 KRAS LLGL1 LLGL2 MAGI1 MAGI2 MAGI3 MLLT4 MPDZ MPP5 MRAS MYH1 MYH10 MYH11 MYH13 MYH14 MYH15 MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8 MYH9 MYL10 MYL12A MYL12B MYL2 MYL5 MYL7 MYL9 MYLPF NRAS OCLN PARD3 PARD6A PARD6B PARD6G PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R2D PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PTEN RAB13 RAB3B RHOA RRAS RRAS2 SPTAN1 SRC SYMPK TJAP1 TJP1 TJP2 TJP3 VAPA YES1 ZAK hsa04540 Gap junction ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRB1 CDK1 CSNK1D DRD1 DRD2 EGF EGFR GJA1 GJD2 GNA11 GNAI1 GNAI2 GNAI3 GNAQ GNAS GRB2 GRM1 GRM5 GUCY1A2 GUCY1A3 GUCY1B3 HRAS HTR2A HTR2B HTR2C ITPR1 ITPR2 ITPR3 KRAS LPAR1 MAP2K1 MAP2K2 MAP2K5 MAP3K2 MAPK1 MAPK3 MAPK7 NRAS PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PLCB1 PLCB2 PLCB3 PLCB4 PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKG1 PRKG2 PRKX RAF1 SOS1 SOS2 SRC TJP1 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA8 TUBAL3 TUBB TUBB1 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4Q TUBB6 TUBB8 hsa04610 Complement and coagulation cascades A2M BDKRB1 BDKRB2 C1QA C1QB C1QC C1R C1S C2 C3 C3AR1 C4A C4B C4BPA C4BPB C5 C5AR1 C6 C7 C8A C8B C8G C9 CD46 CD55 CD59 CFB CFD CFH CFI CPB2 CR1 CR2 F10 F11 F12 F13A1 F13B F2 F2R F3 F5 F7 F8 F9 FGA FGB FGG KLKB1 KNG1 MASP1 MASP2 MBL2 PLAT PLAU PLAUR PLG PROC PROS1 SERPINA1 SERPINA5 SERPINC1 SERPIND1 SERPINE1 SERPINF2 SERPING1 TFPI THBD VWF hsa04612 Antigen processing and presentation 100294318 B2M CALR CANX CD4 CD74 CD8A CD8B CIITA CREB1 CTSB CTSL1 CTSS HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-E HLA-F HLA-G HSP90AA1 HSP90AB1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA4 HSPA5 HSPA6 HSPA8 IFI30 IFNG KIR2DL1 KIR2DL2 KIR2DL3 KIR2DL4 KIR2DL5A KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DL1 KIR3DL2 KIR3DL3 KLRC1 KLRC2 KLRC3 KLRC4 KLRD1 LGMN LOC100133583 LOC652614 NFYA NFYB NFYC PDIA3 PSME1 PSME2 PSME3 RFX5 RFXANK RFXAP TAP1 TAP2 TAPBP TNF hsa04614 Renin-angiotensin system ACE ACE2 AGT AGTR1 AGTR2 ANPEP CMA1 CPA3 CTSA CTSG ENPEP LNPEP MAS1 MME NLN REN THOP1 hsa04620 Toll-like receptor signaling pathway AKT1 AKT2 AKT3 CASP8 CCL3 CCL4 CCL5 CD14 CD40 CD80 CD86 CHUK CTSK CXCL10 CXCL11 CXCL9 FADD FOS IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR1 IFNAR2 IFNB1 IKBKB IKBKE IKBKG IL12A IL12B IL1B IL6 IL8 IRAK1 IRAK4 IRF3 IRF5 IRF7 JUN LBP LY96 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAP3K7 MAP3K8 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK8 MAPK9 MYD88 NFKB1 NFKBIA PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 RAC1 RELA RIPK1 SPP1 STAT1 TAB1 TAB2 TBK1 TICAM1 TICAM2 TIRAP TLR1 TLR2 TLR3 TLR4 TLR5 TLR6 TLR7 TLR8 TLR9 TNF TOLLIP TRAF3 TRAF6 hsa04621 NOD-like receptor signaling pathway BIRC2 BIRC3 CARD18 CARD6 CARD8 CARD9 CASP1 CASP5 CASP8 CCL11 CCL13 CCL2 CCL5 CCL7 CCL8 CHUK CXCL1 CXCL2 ERBB2IP HSP90AA1 HSP90AB1 HSP90B1 IKBKB IKBKG IL18 IL1B IL6 IL8 MAP3K7 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK8 MAPK9 MEFV NAIP NFKB1 NFKBIA NFKBIB NLRC4 NLRP1 NLRP3 NOD1 NOD2 PSTPIP1 PYCARD PYDC1 RELA RIPK2 SUGT1 TAB1 TAB2 TAB3 TNF TNFAIP3 TRAF6 TRIP6 XIAP hsa04622 RIG-I-like receptor signaling pathway ATG12 ATG5 AZI2 CASP10 CASP8 CHUK CXCL10 CYLD DAK DDX3X DDX3Y DDX58 DHX58 FADD IFIH1 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB1 IFNE IFNK IFNW1 IKBKB IKBKE IKBKG IL12A IL12B IL8 IRF3 IRF7 ISG15 MAP3K1 MAP3K7 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK8 MAPK9 MAVS NFKB1 NFKBIA NFKBIB NLRX1 OTUD5 PIN1 RELA RIPK1 RNF125 SIKE1 TANK TBK1 TBKBP1 TMEM173 TNF TRADD TRAF2 TRAF3 TRAF6 TRIM25 hsa04623 Cytosolic DNA-sensing pathway ADAR AIM2 CASP1 CCL4 CCL4L1 CCL4L2 CCL5 CHUK CXCL10 DDX58 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNB1 IKBKB IKBKE IKBKG IL18 IL1B IL33 IL6 IRF3 IRF7 MAVS NFKB1 NFKBIA NFKBIB POLR1C POLR1D POLR3A POLR3B POLR3C POLR3D POLR3F POLR3G POLR3GL POLR3H POLR3K PYCARD RELA RIPK1 RIPK3 TBK1 TMEM173 TREX1 ZBP1 hsa04630 Jak-STAT signaling pathway AKT1 AKT2 AKT3 BCL2L1 CBL CBLB CBLC CCND1 CCND2 CCND3 CISH CLCF1 CNTF CNTFR CREBBP CRLF2 CSF2 CSF2RA CSF2RB CSF3 CSF3R CSH1 CTF1 EP300 EPO EPOR GH1 GH2 GHR GRB2 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR1 IFNAR2 IFNB1 IFNE IFNG IFNGR1 IFNGR2 IFNK IFNW1 IL10 IL10RA IL10RB IL11 IL11RA IL12A IL12B IL12RB1 IL12RB2 IL13 IL13RA1 IL13RA2 IL15 IL15RA IL19 IL2 IL20 IL20RA IL20RB IL21 IL21R IL22 IL22RA1 IL22RA2 IL23A IL23R IL24 IL26 IL28A IL28B IL28RA IL29 IL2RA IL2RB IL2RG IL3 IL3RA IL4 IL4R IL5 IL5RA IL6 IL6R IL6ST IL7 IL7R IL9 IL9R IRF9 JAK1 JAK2 JAK3 LEP LEPR LIF LIFR MPL MYC OSM OSMR PIAS1 PIAS2 PIAS3 PIAS4 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIM1 PRL PRLR PTPN11 PTPN6 SOCS1 SOCS2 SOCS3 SOCS4 SOCS5 SOCS7 SOS1 SOS2 SPRED1 SPRED2 SPRY1 SPRY2 SPRY3 SPRY4 STAM STAM2 STAT1 STAT2 STAT3 STAT4 STAT5A STAT5B STAT6 TPO TSLP TYK2 hsa04640 Hematopoietic cell lineage 652799 ANPEP CD14 CD19 CD1A CD1B CD1C CD1D CD1E CD2 CD22 CD33 CD34 CD36 CD37 CD38 CD3D CD3E CD3G CD4 CD44 CD5 CD55 CD59 CD7 CD8A CD8B CD9 CR1 CR2 CSF1 CSF1R CSF2 CSF2RA CSF3 CSF3R DNTT EPO EPOR FCER2 FCGR1A FLT3 FLT3LG GP1BA GP1BB GP5 GP9 GYPA HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 IL11 IL11RA IL1A IL1B IL1R1 IL1R2 IL2RA IL3 IL3RA IL4 IL4R IL5 IL5RA IL6 IL6R IL7 IL7R IL9R ITGA1 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGAM ITGB3 KIT KITLG MME MS4A1 TFRC THPO TNF TPO hsa04650 Natural killer cell mediated cytotoxicity 4276 ARAF BID BRAF CASP3 CD244 CD247 CD48 CHP CHP2 CSF2 FAS FASLG FCER1G FCGR3A FCGR3B FYN GRB2 GZMB HCST HLA-A HLA-B HLA-C HLA-E HLA-G HRAS ICAM1 ICAM2 IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IFNAR1 IFNAR2 IFNB1 IFNG IFNGR1 IFNGR2 ITGAL ITGB2 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DL4 KIR2DL5A KIR2DS1 KIR2DS3 KIR2DS4 KIR2DS5 KIR3DL1 KIR3DL2 KLRC1 KLRC2 KLRC3 KLRD1 KLRK1 KRAS LAT LCK LCP2 MAP2K1 MAP2K2 MAPK1 MAPK3 MICB NCR1 NCR2 NCR3 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NRAS PAK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCG1 PLCG2 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRF1 PRKCA PRKCB PRKCG PTK2B PTPN11 PTPN6 RAC1 RAC2 RAC3 RAET1E RAET1G RAET1L RAF1 SH2D1A SH2D1B SH3BP2 SHC1 SHC2 SHC3 SHC4 SOS1 SOS2 SYK TNF TNFRSF10A TNFRSF10B TNFRSF10C TNFRSF10D TNFSF10 TYROBP ULBP1 ULBP2 ULBP3 VAV1 VAV2 VAV3 ZAP70 hsa04660 T cell receptor signaling pathway AKT1 AKT2 AKT3 BCL10 CARD11 CBL CBLB CBLC CD247 CD28 CD3D CD3E CD3G CD4 CD40LG CD8A CD8B CDC42 CDK4 CHP CHP2 CHUK CSF2 CTLA4 DLG1 FOS FYN GRAP2 GRB2 GSK3B HRAS ICOS IFNG IKBKB IKBKG IL10 IL2 IL4 IL5 ITK JUN KRAS LAT LCK LCP2 MALT1 MAP2K1 MAP2K2 MAP2K7 MAP3K14 MAP3K7 MAP3K8 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK9 NCK1 NCK2 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NFKB1 NFKBIA NFKBIB NFKBIE NRAS PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PDCD1 PDK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCG1 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKCQ PTPN6 PTPRC RAF1 RASGRP1 RELA RHOA SOS1 SOS2 TEC TNF VAV1 VAV2 VAV3 ZAP70 hsa04662 B cell receptor signaling pathway AKT1 AKT2 AKT3 BCL10 BLNK BTK CARD11 CD19 CD22 CD72 CD79A CD79B CD81 CHP CHP2 CHUK CR2 DAPP1 FCGR2B FOS GRB2 GSK3B HRAS IFITM1 IKBKB IKBKG INPP5D JUN KRAS LILRB3 LYN MALT1 MAP2K1 MAP2K2 MAPK1 MAPK3 NFAT5 NFATC1 NFATC2 NFATC3 NFATC4 NFKB1 NFKBIA NFKBIB NFKBIE NRAS PIK3AP1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCG2 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKCB PTPN6 RAC1 RAC2 RAC3 RAF1 RASGRP3 RELA SOS1 SOS2 SYK VAV1 VAV2 VAV3 hsa04664 Fc epsilon RI signaling pathway AKT1 AKT2 AKT3 BTK CSF2 FCER1A FCER1G FYN GAB2 GRB2 HRAS IL13 IL3 IL4 IL5 INPP5D JMJD7-PLA2G4B KRAS LAT LCP2 LYN MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK8 MAPK9 MS4A2 NRAS PDK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PLCG1 PLCG2 PRKCA PRKCB PRKCD PRKCE RAC1 RAC2 RAC3 RAF1 SOS1 SOS2 SYK TNF VAV1 VAV2 VAV3 hsa04666 Fc gamma R-mediated phagocytosis AKT1 AKT2 AKT3 AMPH ARF6 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ARPC5L ASAP1 ASAP2 ASAP3 CDC42 CFL1 CFL2 CRK CRKL DNM1 DNM1L DNM2 DNM3 DOCK2 FCGR1A FCGR2A FCGR2B FCGR2C FCGR3A GAB2 GSN HCK INPP5D LAT LIMK1 LIMK2 LOC653888 LYN MAP2K1 MAPK1 MAPK3 MARCKS MARCKSL1 MYO10 NCF1 PAK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIP5K1A PIP5K1B PIP5K1C PLA2G4A PLA2G4B PLA2G4D PLA2G4E PLA2G4F PLA2G6 PLCG1 PLCG2 PLD1 PLD2 PPAP2A PPAP2B PPAP2C PRKCA PRKCB PRKCD PRKCE PRKCG PTPRC RAC1 RAC2 RAF1 RPS6KB1 RPS6KB2 SCIN SPHK1 SPHK2 SYK VASP VAV1 VAV2 VAV3 WAS WASF1 WASF2 WASF3 WASL hsa04670 Leukocyte transendothelial migration 646048 646821 ACTB ACTG1 ACTN1 ACTN2 ACTN3 ACTN4 ARHGAP5 BCAR1 CD99 CDC42 CDH5 CLDN1 CLDN10 CLDN11 CLDN14 CLDN15 CLDN16 CLDN17 CLDN18 CLDN19 CLDN2 CLDN20 CLDN22 CLDN23 CLDN3 CLDN4 CLDN5 CLDN6 CLDN7 CLDN8 CLDN9 CTNNA1 CTNNA2 CTNNA3 CTNNB1 CTNND1 CXCL12 CXCR4 CYBA CYBB ESAM EZR F11R GNAI1 GNAI2 GNAI3 GRLF1 ICAM1 ITGA4 ITGAL ITGAM ITGB1 ITGB2 ITK JAM2 JAM3 MAPK11 MAPK12 MAPK13 MAPK14 MLLT4 MMP2 MMP9 MSN MYL10 MYL12A MYL12B MYL2 MYL5 MYL7 MYL9 MYLPF NCF1 NCF2 NCF4 NOX1 NOX3 OCLN PECAM1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCG1 PLCG2 PRKCA PRKCB PRKCG PTK2 PTK2B PTPN11 PXN RAC1 RAC2 RAP1A RAP1B RAPGEF3 RAPGEF4 RASSF5 RHOA RHOH ROCK1 ROCK2 SIPA1 THY1 TXK VASP VAV1 VAV2 VAV3 VCAM1 VCL hsa04672 Intestinal immune network for IgA production 100294318 AICDA CCL25 CCL27 CCL28 CCR10 CCR9 CD28 CD40 CD40LG CD80 CD86 CXCL12 CXCR4 HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 ICOS ICOSLG IL10 IL15 IL15RA IL2 IL4 IL5 IL6 ITGA4 ITGB7 LOC100133583 LTBR MADCAM1 MAP3K14 PIGR TGFB1 TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13 TNFSF13B hsa04710 Circadian rhythm - mammal ARNTL BHLHE40 BHLHE41 BTRC CLOCK CRY1 CRY2 CSNK1D CSNK1E CUL1 FBXL3 FBXW11 LOC728622 NPAS2 NR1D1 PER1 PER2 PER3 RBX1 RORA RORB RORC SKP1 hsa04720 Long-term potentiation ADCY1 ADCY8 ARAF ATF4 BRAF CACNA1C CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMK2A CAMK2B CAMK2D CAMK2G CAMK4 CHP CHP2 CREBBP EP300 GNAQ GRIA1 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRM1 GRM5 HRAS ITPR1 ITPR2 ITPR3 KRAS MAP2K1 MAP2K2 MAPK1 MAPK3 NRAS PLCB1 PLCB2 PLCB3 PLCB4 PPP1CA PPP1CB PPP1CC PPP1R12A PPP1R1A PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKX RAF1 RAP1A RAP1B RAPGEF3 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 hsa04722 Neurotrophin signaling pathway ABL1 AKT1 AKT2 AKT3 ARHGDIA ARHGDIB ATF4 BAD BAX BCL2 BDNF BRAF CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMK2A CAMK2B CAMK2D CAMK2G CAMK4 CDC42 CRK CRKL CSK FASLG FOXO3 FRS2 GAB1 GRB2 GSK3B HRAS IKBKB IRAK1 IRAK2 IRAK3 IRAK4 IRS1 IRS2 IRS4 JUN KIDINS220 KRAS MAGED1 MAP2K1 MAP2K2 MAP2K5 MAP2K7 MAP3K1 MAP3K3 MAP3K5 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK7 MAPK8 MAPK9 MAPKAPK2 NFKB1 NFKBIA NFKBIB NFKBIE NGF NGFR NGFRAP1 NRAS NTF3 NTF4 NTRK1 NTRK2 NTRK3 PDK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCG1 PLCG2 PRDM4 PRKCD PSEN1 PTPN11 RAC1 RAF1 RAP1A RAP1B RAPGEF1 RELA RHOA RIPK2 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KA5 RPS6KA6 SH2B1 SH2B2 SH2B3 SHC1 SHC2 SHC3 SHC4 SORT1 SOS1 SOS2 TP53 TP73 TRAF6 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZNF274 hsa04730 Long-term depression ARAF BRAF C7orf16 CACNA1A CRH CRHR1 GNA11 GNA12 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAS GNAZ GRIA1 GRIA2 GRIA3 GRID2 GRM1 GRM5 GUCY1A2 GUCY1A3 GUCY1B3 HRAS IGF1 IGF1R ITPR1 ITPR2 ITPR3 JMJD7-PLA2G4B KRAS LYN MAP2K1 MAP2K2 MAPK1 MAPK3 NOS1 NRAS PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PLCB1 PLCB2 PLCB3 PLCB4 PPP2CA PPP2CB PPP2R1A PPP2R1B PRKCA PRKCB PRKCG PRKG1 PRKG2 RAF1 RYR1 hsa04740 Olfactory transduction 8385 ADCY3 ADRBK2 ARRB2 CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMK2A CAMK2B CAMK2D CAMK2G CLCA1 CLCA2 CLCA4 CNGA3 CNGA4 CNGB1 GNAL GUCA1A GUCA1B GUCA1C GUCY2D OR10A2 OR10A3 OR10A4 OR10A5 OR10A6 OR10A7 OR10AD1 OR10AG1 OR10C1 OR10G2 OR10G3 OR10G4 OR10G7 OR10G8 OR10G9 OR10H1 OR10H2 OR10H3 OR10H4 OR10H5 OR10J1 OR10J3 OR10J5 OR10K1 OR10K2 OR10P1 OR10Q1 OR10R2 OR10S1 OR10T2 OR10V1 OR10X1 OR10Z1 OR11A1 OR11G2 OR11H1 OR11H4 OR11H6 OR11L1 OR12D2 OR12D3 OR13A1 OR13C2 OR13C3 OR13C4 OR13C5 OR13C8 OR13C9 OR13D1 OR13F1 OR13G1 OR13H1 OR13J1 OR14A16 OR14C36 OR14I1 OR14J1 OR1A1 OR1A2 OR1B1 OR1C1 OR1D2 OR1D5 OR1E1 OR1E2 OR1F1 OR1G1 OR1I1 OR1J1 OR1J2 OR1J4 OR1K1 OR1L1 OR1L3 OR1L4 OR1L6 OR1L8 OR1M1 OR1N1 OR1N2 OR1Q1 OR1S1 OR1S2 OR2A1 OR2A12 OR2A14 OR2A2 OR2A25 OR2A4 OR2A42 OR2A5 OR2A7 OR2AE1 OR2AG1 OR2AG2 OR2AK2 OR2AT4 OR2B11 OR2B2 OR2B3 OR2B6 OR2C1 OR2C3 OR2D2 OR2D3 OR2F1 OR2F2 OR2G2 OR2G3 OR2G6 OR2H1 OR2H2 OR2J2 OR2J3 OR2K2 OR2L13 OR2L2 OR2L3 OR2L8 OR2M2 OR2M3 OR2M4 OR2M5 OR2M7 OR2S2 OR2T1 OR2T10 OR2T11 OR2T12 OR2T2 OR2T27 OR2T29 OR2T3 OR2T33 OR2T34 OR2T4 OR2T5 OR2T6 OR2T8 OR2V2 OR2W1 OR2W3 OR2Y1 OR2Z1 OR3A1 OR3A2 OR3A3 OR4A15 OR4A16 OR4A47 OR4A5 OR4B1 OR4C11 OR4C12 OR4C13 OR4C15 OR4C16 OR4C3 OR4C45 OR4C46 OR4C6 OR4D1 OR4D10 OR4D11 OR4D2 OR4D5 OR4D6 OR4D9 OR4E2 OR4F15 OR4F16 OR4F17 OR4F3 OR4F4 OR4F5 OR4F6 OR4K1 OR4K13 OR4K14 OR4K15 OR4K17 OR4K2 OR4K5 OR4L1 OR4M1 OR4M2 OR4N2 OR4N4 OR4N5 OR4P4 OR4Q3 OR4S1 OR4S2 OR4X1 OR4X2 OR51A2 OR51A4 OR51A7 OR51B2 OR51B4 OR51B5 OR51B6 OR51D1 OR51E1 OR51E2 OR51F1 OR51F2 OR51G1 OR51G2 OR51I1 OR51I2 OR51L1 OR51M1 OR51Q1 OR51S1 OR51T1 OR51V1 OR52A1 OR52A5 OR52B2 OR52B4 OR52B6 OR52D1 OR52E2 OR52E4 OR52E6 OR52E8 OR52H1 OR52I1 OR52I2 OR52J3 OR52K1 OR52K2 OR52L1 OR52M1 OR52N1 OR52N2 OR52N4 OR52N5 OR52R1 OR52W1 OR56A1 OR56A3 OR56A4 OR56A5 OR56B1 OR56B4 OR5A1 OR5A2 OR5AC2 OR5AK2 OR5AN1 OR5AP2 OR5AR1 OR5AS1 OR5AU1 OR5B12 OR5B17 OR5B21 OR5B3 OR5C1 OR5D13 OR5D14 OR5D16 OR5D18 OR5F1 OR5H2 OR5H6 OR5I1 OR5J2 OR5K1 OR5K2 OR5L1 OR5L2 OR5M1 OR5M10 OR5M11 OR5M3 OR5M8 OR5M9 OR5P2 OR5P3 OR5R1 OR5T1 OR5T2 OR5T3 OR5V1 OR6A2 OR6B1 OR6B2 OR6B3 OR6C1 OR6C2 OR6C3 OR6C4 OR6C6 OR6C65 OR6C68 OR6C70 OR6C74 OR6C75 OR6C76 OR6F1 OR6K2 OR6K3 OR6K6 OR6M1 OR6N1 OR6N2 OR6Q1 OR6S1 OR6T1 OR6V1 OR6X1 OR6Y1 OR7A10 OR7A17 OR7A5 OR7C1 OR7C2 OR7D2 OR7D4 OR7E24 OR7G1 OR7G2 OR7G3 OR8A1 OR8B12 OR8B4 OR8B8 OR8D1 OR8D2 OR8D4 OR8G1 OR8G2 OR8G5 OR8H1 OR8H2 OR8H3 OR8I2 OR8J1 OR8J3 OR8K1 OR8K3 OR8K5 OR8S1 OR8U1 OR8U8 OR9A2 OR9A4 OR9G1 OR9G4 OR9I1 OR9K2 OR9Q1 OR9Q2 PDC PDE1C PRKACA PRKACB PRKACG PRKG1 PRKG2 PRKX hsa04742 Taste transduction ACCN1 ADCY4 ADCY6 ADCY8 CACNA1A CACNA1B GNAS GNAT3 GNB1 GNB3 GNG13 GNG3 GRM4 ITPR3 KCNB1 PDE1A PLCB2 PRKACA PRKACB PRKACG PRKX SCNN1A SCNN1B SCNN1G TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R13 TAS2R14 TAS2R16 TAS2R19 TAS2R20 TAS2R3 TAS2R31 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R42 TAS2R43 TAS2R45 TAS2R46 TAS2R5 TAS2R50 TAS2R60 TAS2R7 TAS2R8 TAS2R9 TRPM5 hsa04744 Phototransduction ARRB1 ARRB2 CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CNGA1 CNGB1 GNAT1 GNAT2 GNAT3 GNB1 GNGT1 GRK1 GRK7 GUCA1A GUCA1B GUCA1C GUCY2D GUCY2F PDE6A PDE6B PDE6G RCVRN RGS9 RHO SLC24A1 hsa04810 Regulation of actin cytoskeleton 646048 646821 ABI2 ACTB ACTG1 ACTN1 ACTN2 ACTN3 ACTN4 APC APC2 ARAF ARHGEF1 ARHGEF12 ARHGEF4 ARHGEF6 ARHGEF7 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ARPC5L BAIAP2 BCAR1 BDKRB1 BDKRB2 BRAF C3orf10 CD14 CDC42 CFL1 CFL2 CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRK CRKL CSK CYFIP1 CYFIP2 DIAPH1 DIAPH2 DIAPH3 DOCK1 EGF EGFR ENAH EZR F2 F2R FGD1 FGD3 FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR2 FGFR3 FGFR4 FN1 GIT1 GNA12 GNA13 GNG12 GRLF1 GSN HRAS INS INSRR IQGAP1 IQGAP2 IQGAP3 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGAX ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 KRAS LIMK1 LIMK2 LOC653888 MAP2K1 MAP2K2 MAPK1 MAPK3 MOS MRAS MSN MYH10 MYH14 MYH9 MYL10 MYL12A MYL12B MYL2 MYL5 MYL7 MYL9 MYLK MYLK2 MYLK3 MYLPF NCKAP1 NCKAP1L NRAS PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PFN1 PFN2 PFN3 PFN4 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIKFYVE PIP4K2A PIP4K2B PIP4K2C PIP5K1A PIP5K1B PIP5K1C PPP1CA PPP1CB PPP1CC PPP1R12A PTK2 PXN RAC1 RAC2 RAC3 RAF1 RDX RHOA ROCK1 ROCK2 RRAS RRAS2 SCIN SLC9A1 SOS1 SOS2 SSH1 SSH2 SSH3 TIAM1 TIAM2 TMSB4X TMSB4Y TMSL3 VAV1 VAV2 VAV3 VCL WAS WASF1 WASF2 WASL hsa04910 Insulin signaling pathway ACACA ACACB AKT1 AKT2 AKT3 ARAF BAD BRAF CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CBL CBLB CBLC CRK CRKL EIF4E EIF4E1B EIF4E2 EIF4EBP1 ELK1 EXOC7 FASN FBP1 FBP2 FLOT1 FLOT2 FOXO1 G6PC G6PC2 GCK GRB2 GSK3B GYS1 GYS2 HK1 HK2 HK3 HRAS IKBKB INPP5D INPP5K INS INSR IRS1 IRS2 IRS4 KRAS LIPE MAP2K1 MAP2K2 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MKNK1 MKNK2 MTOR NRAS PCK1 PCK2 PDE3A PDE3B PDPK1 PHKA1 PHKA2 PHKB PHKG1 PHKG2 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PKLR PPARGC1A PPP1CA PPP1CB PPP1CC PPP1R3A PPP1R3B PPP1R3C PPP1R3D PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKACA PRKACB PRKACG PRKAG1 PRKAG2 PRKAG3 PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCI PRKCZ PRKX PTPN1 PTPRF PYGB PYGL PYGM RAF1 RAPGEF1 RHEB RHOQ RPS6 RPS6KB1 RPS6KB2 RPTOR SH2B2 SHC1 SHC2 SHC3 SHC4 SLC2A4 SOCS1 SOCS2 SOCS3 SOCS4 SORBS1 SOS1 SOS2 SREBF1 TRIP10 TSC1 TSC2 hsa04912 GnRH signaling pathway ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ATF4 CACNA1C CACNA1D CACNA1F CACNA1S CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMK2A CAMK2B CAMK2D CAMK2G CDC42 CGA EGFR ELK1 FSHB GNA11 GNAQ GNAS GNRH1 GNRH2 GNRHR GRB2 HBEGF HRAS ITPR1 ITPR2 ITPR3 JMJD7-PLA2G4B JUN KRAS LHB MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K6 MAP2K7 MAP3K1 MAP3K2 MAP3K3 MAP3K4 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK7 MAPK8 MAPK9 MMP14 MMP2 NRAS PLA2G10 PLA2G12A PLA2G12B PLA2G1B PLA2G2A PLA2G2C PLA2G2D PLA2G2E PLA2G2F PLA2G3 PLA2G4A PLA2G4B PLA2G4E PLA2G5 PLA2G6 PLCB1 PLCB2 PLCB3 PLCB4 PLD1 PLD2 PRKACA PRKACB PRKACG PRKCA PRKCB PRKCD PRKX PTK2B RAF1 SOS1 SOS2 SRC hsa04914 Progesterone-mediated oocyte maturation ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 AKT1 AKT2 AKT3 ANAPC1 ANAPC10 ANAPC11 ANAPC13 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ARAF BRAF BUB1 CCNA1 CCNA2 CCNB1 CCNB2 CCNB3 CDC16 CDC23 CDC25A CDC25B CDC25C CDC26 CDC27 CDK1 CDK2 CPEB1 FZR1 GNAI1 GNAI2 GNAI3 HSP90AA1 HSP90AB1 IGF1 IGF1R INS KRAS LOC650621 MAD1L1 MAD2L1 MAD2L2 MAP2K1 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK8 MAPK9 MOS PDE3A PDE3B PGR PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PKMYT1 PLK1 PRKACA PRKACB PRKACG PRKX RAF1 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA6 SPDYA SPDYC hsa04916 Melanogenesis 652799 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ASIP CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMK2A CAMK2B CAMK2D CAMK2G CREB1 CREB3 CREB3L1 CREB3L2 CREB3L3 CREB3L4 CREBBP CTNNB1 DCT DVL1 DVL2 DVL3 EDN1 EDNRB EP300 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAS GSK3B HRAS KIT KITLG KRAS LEF1 MAP2K1 MAP2K2 MAPK1 MAPK3 MC1R MITF NRAS PLCB1 PLCB2 PLCB3 PLCB4 POMC PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKX RAF1 TCF7 TCF7L1 TCF7L2 TYR TYRP1 WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B hsa04920 Adipocytokine signaling pathway ACACB ACSL1 ACSL3 ACSL4 ACSL5 ACSL6 ADIPOQ ADIPOR1 ADIPOR2 AGRP AKT1 AKT2 AKT3 CAMKK1 CAMKK2 CD36 CHUK CPT1A CPT1B CPT1C G6PC G6PC2 IKBKB IKBKG IRS1 IRS2 IRS4 JAK2 LEP LEPR MAPK10 MAPK8 MAPK9 MTOR NFKB1 NFKBIA NFKBIB NFKBIE NPY PCK1 PCK2 POMC PPARA PPARGC1A PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 PRKCQ PTPN11 RELA RXRA RXRB RXRG SLC2A1 SLC2A4 SOCS3 STAT3 STK11 TNF TNFRSF1A TNFRSF1B TRADD TRAF2 hsa04930 Type II diabetes mellitus ABCC8 ADIPOQ CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1G GCK HK1 HK2 HK3 IKBKB INS INSR IRS1 IRS2 IRS4 KCNJ11 MAFA MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MTOR PDX1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PKLR PKM2 PRKCD PRKCE PRKCZ SLC2A2 SLC2A4 SOCS1 SOCS2 SOCS3 SOCS4 TNF hsa04940 Type I diabetes mellitus 100294318 CD28 CD80 CD86 CPE FAS FASLG GAD1 GAD2 GZMB HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-E HLA-F HLA-G HSPD1 ICA1 IFNG IL12A IL12B IL1A IL1B IL2 INS LOC100133583 LOC652614 LTA PRF1 PTPRN PTPRN2 TNF hsa04950 Maturity onset diabetes of the young BHLHA15 FOXA2 FOXA3 GCK HES1 HHEX HNF1A HNF1B HNF4A HNF4G IAPP INS MAFA MNX1 NEUROD1 NEUROG3 NKX2-2 NKX6-1 NR5A2 ONECUT1 PAX4 PAX6 PDX1 PKLR SLC2A2 hsa04960 Aldosterone-regulated sodium reabsorption ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP1B4 FXYD2 FXYD4 HSD11B1 HSD11B2 IGF1 INS INSR IRS1 IRS2 IRS4 KCNJ1 KRAS MAPK1 MAPK3 NEDD4L NR3C2 PDPK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PRKCA PRKCB PRKCG SCNN1A SCNN1B SCNN1G SFN SGK1 SLC9A3R2 hsa04962 Vasopressin-regulated water reabsorption ADCY3 ADCY6 ADCY9 AQP2 AQP3 AQP4 ARHGDIA ARHGDIB AVP AVPR2 CREB1 CREB3 CREB3L1 CREB3L2 CREB3L3 CREB3L4 CREB5 DCTN1 DCTN2 DCTN4 DCTN5 DCTN6 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNC2H1 DYNC2LI1 DYNLL1 DYNLL2 GNAS NSF PRKACA PRKACB PRKACG PRKX RAB11A RAB11B RAB5A RAB5B RAB5C STX4 VAMP2 hsa04964 Proximal tubule bicarbonate reclamation AQP1 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP1B4 CA2 CA4 FXYD2 GLS GLS2 GLUD1 GLUD2 MDH1 PCK1 PCK2 SLC25A10 SLC38A3 SLC4A4 SLC9A3 hsa04966 Collecting duct acid secretion ATP4A ATP4B ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 CA2 CLCNKB SLC12A7 SLC4A1 TCIRG1 hsa04970 Salivary secretion ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 AMY1A AMY1B AMY1C AQP5 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP1B4 ATP2B1 ATP2B2 ATP2B3 ATP2B4 BEST2 BST1 CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMP CD38 CHRM3 CST1 CST2 CST3 CST4 CST5 DMBT1 FXYD2 GNAQ GNAS GUCY1A2 GUCY1A3 GUCY1B3 HTN1 ITPR1 ITPR2 ITPR3 KCNMA1 KCNN4 LPO LYZ MUC5B MUC7 NOS1 PLCB1 PLCB2 PLCB3 PLCB4 PRB1 PRB2 PRH1 PRH2 PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKG1 PRKG2 PRKX RYR3 SLC12A2 SLC4A2 SLC9A1 STATH TRPV6 VAMP2 hsa04971 Gastric acid secretion ACTB ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP1B4 ATP4A ATP4B CA2 CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMK2A CAMK2B CAMK2D CAMK2G CCKBR CFTR CHRM3 EZR GAST GNAI1 GNAI2 GNAI3 GNAQ GNAS HRH2 ITPR1 ITPR2 ITPR3 KCNE2 KCNJ1 KCNJ10 KCNJ15 KCNJ16 KCNJ2 KCNK10 KCNK2 KCNQ1 MYLK MYLK2 MYLK3 PLCB1 PLCB2 PLCB3 PLCB4 PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKX SLC26A7 SLC4A2 SLC9A1 SLC9A4 SST SSTR2 hsa05010 Alzheimer's disease 100133737 ADAM10 ADAM17 APAF1 APBB1 APH1A APOE APP ATF6 ATP2A1 ATP2A2 ATP2A3 ATP5A1 ATP5B ATP5C1 ATP5D ATP5E ATP5F1 ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5J ATP5O ATP6 ATP8 BACE1 BACE2 BAD BID CACNA1C CACNA1D CACNA1F CACNA1S CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAPN1 CAPN2 CASP3 CASP7 CASP8 CASP9 CDK5 CDK5R1 CHP CHP2 COX1 COX2 COX3 COX4I1 COX4I2 COX5A COX5B COX6A1 COX6A2 COX6B1 COX6B2 COX6C COX7A1 COX7A2 COX7A2L COX7B COX7B2 COX7C COX8A COX8C CYC1 CYCS CYTB EIF2AK3 ERN1 FADD FAS GAPDH GNAQ GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GSK3B HSD17B10 IDE IL1B ITPR1 ITPR2 ITPR3 LOC100130247 LOC390424 LOC644310 LOC727947 LPL LRP1 MAPK1 MAPK3 MAPT MME NAE1 NCSTN NDUFA1 NDUFA10 NDUFA2 NDUFA3 NDUFA4 NDUFA4L2 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFB1 NDUFB10 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 NOS1 PLCB1 PLCB2 PLCB3 PLCB4 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PSEN1 PSEN2 PSENEN RYR3 SDHA SDHB SDHC SDHD SNCA TNF TNFRSF1A UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRHL UQCRQ hsa05012 Parkinson's disease 100133737 APAF1 ATP5A1 ATP5B ATP5C1 ATP5D ATP5E ATP5F1 ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5J ATP5O ATP6 ATP8 CASP3 CASP9 COX1 COX2 COX3 COX4I1 COX4I2 COX5A COX5B COX6A1 COX6A2 COX6B1 COX6B2 COX6C COX7A1 COX7A2 COX7A2L COX7B COX7B2 COX7C COX8A COX8C CYC1 CYCS CYTB GPR37 HTRA2 LOC100130247 LOC390424 LOC644310 LOC727947 LOC729317 LRRK2 ND1 ND2 ND3 ND4 ND4L ND5 ND6 NDUFA1 NDUFA10 NDUFA2 NDUFA3 NDUFA4 NDUFA4L2 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFB1 NDUFB10 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 PARK2 PARK7 PINK1 PPID SDHA SDHB SDHC SDHD SEPT5 SLC18A1 SLC18A2 SLC25A31 SLC25A4 SLC25A5 SLC25A6 SLC6A3 SNCA SNCAIP TH UBA1 UBA7 UBB UBE2G1 UBE2G2 UBE2J1 UBE2J2 UBE2L3 UBE2L6 UCHL1 UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRHL UQCRQ VDAC1 VDAC2 VDAC3 hsa05014 Amyotrophic lateral sclerosis (ALS) ALS2 APAF1 BAD BAX BCL2 BCL2L1 BID CASP1 CASP3 CASP9 CAT CCS CHP CHP2 CYCS DAXX DERL1 GPX1 GRIA1 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D MAP2K3 MAP2K6 MAP3K5 MAPK11 MAPK12 MAPK13 MAPK14 NEFH NEFL NEFM NOS1 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRPH PRPH2 RAB5A RAC1 SLC1A2 SOD1 TNF TNFRSF1A TNFRSF1B TOMM40 TOMM40L TP53 hsa05016 Huntington's disease 100133737 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APAF1 ATP5A1 ATP5B ATP5C1 ATP5D ATP5E ATP5F1 ATP5G1 ATP5G2 ATP5G3 ATP5H ATP5J ATP5O ATP6 ATP8 BAX BBC3 BDNF CASP3 CASP8 CASP9 CLTA CLTB CLTC CLTCL1 COX1 COX2 COX3 COX4I1 COX4I2 COX5A COX5B COX6A1 COX6A2 COX6B1 COX6B2 COX6C COX7A1 COX7A2 COX7A2L COX7B COX7B2 COX7C COX8A COX8C CREB1 CREB3 CREB3L1 CREB3L2 CREB3L3 CREB3L4 CREB5 CREBBP CYC1 CYCS CYTB DCTN1 DCTN2 DCTN4 DLG4 DNAH1 DNAH2 DNAH3 DNAI1 DNAI2 DNAL1 DNAL4 DNALI1 EP300 GNAQ GPX1 GRIN1 GRIN2B GRM5 HAP1 HDAC1 HDAC2 HIP1 HTT IFT57 ITPR1 LOC100130247 LOC390424 LOC644310 LOC727947 LOC729317 NDUFA1 NDUFA10 NDUFA2 NDUFA3 NDUFA4 NDUFA4L2 NDUFA5 NDUFA6 NDUFA7 NDUFA8 NDUFA9 NDUFAB1 NDUFB1 NDUFB10 NDUFB2 NDUFB3 NDUFB4 NDUFB5 NDUFB6 NDUFB7 NDUFB8 NDUFB9 NDUFC1 NDUFC2 NDUFS1 NDUFS2 NDUFS3 NDUFS4 NDUFS5 NDUFS6 NDUFS7 NDUFS8 NDUFV1 NDUFV2 NDUFV3 NRF1 PLCB1 PLCB2 PLCB3 PLCB4 POLR2A POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2J POLR2J2 POLR2J3 POLR2K POLR2L PPARG PPARGC1A PPID RCOR1 REST SDHA SDHB SDHC SDHD SIN3A SLC25A31 SLC25A4 SLC25A5 SLC25A6 SOD1 SOD2 SP1 TAF4 TAF4B TBP TBPL1 TBPL2 TFAM TGM2 TP53 UCP1 UQCR10 UQCR11 UQCRB UQCRC1 UQCRC2 UQCRFS1 UQCRH UQCRHL UQCRQ VDAC1 VDAC2 VDAC3 hsa05020 Prion diseases BAX C1QA C1QB C1QC C5 C6 C7 C8A C8B C8G C9 CCL5 EGR1 ELK1 FYN HSPA1A HSPA5 IL1A IL1B IL6 LAMC1 MAP2K1 MAP2K2 MAPK1 MAPK3 NCAM1 NCAM2 NOTCH1 PRKACA PRKACB PRKACG PRKX PRNP SOD1 STIP1 hsa05100 Bacterial invasion of epithelial cells 646048 646821 ACTB ACTG1 ARHGAP10 ARHGEF26 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ARPC5L BCAR1 CAV1 CAV2 CAV3 CBL CBLB CBLC CD2AP CDC42 CDH1 CLTA CLTB CLTC CLTCL1 CRK CRKL CTNNA1 CTNNA2 CTNNA3 CTNNB1 CTTN DNM1 DNM1L DNM2 DNM3 DOCK1 ELMO1 FN1 GAB1 HCLS1 ILK ITGA5 ITGB1 LOC653888 MAD2L2 MET PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PTK2 PXN RAC1 RHOA RHOG SEPT1 SHC1 SHC2 SHC3 SHC4 SRC VCL WAS WASF1 WASF2 WASL hsa05110 Vibrio cholerae infection 646048 646821 ACTB ACTG1 ADCY3 ADCY9 ARF1 ATP6AP1 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H CFTR ERO1L GNAS KCNQ1 KDELR1 KDELR2 KDELR3 MUC2 PDIA4 PLCG1 PLCG2 PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKX SEC61A1 SEC61A2 SEC61B SEC61G SLC12A2 TCIRG1 TJP1 TJP2 hsa05120 Epithelial cell signaling in Helicobacter pylori infection ADAM10 ADAM17 ATP6AP1 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1D ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H CASP3 CCL5 CDC42 CHUK CSK CXCL1 CXCR1 CXCR2 EGFR F11R GIT1 HBEGF IGSF5 IKBKB IKBKG IL8 JAM2 JAM3 JUN LYN MAP2K4 MAP3K14 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK8 MAPK9 MET NFKB1 NFKBIA NOD1 PAK1 PLCG1 PLCG2 PTPN11 PTPRZ1 RAC1 RELA SRC TCIRG1 TJP1 hsa05130 Pathogenic Escherichia coli infection 646048 646821 ABL1 ACTB ACTG1 ARHGEF2 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ARPC5L CD14 CDC42 CDH1 CLDN1 CTNNB1 CTTN EZR FYN HCLS1 ITGB1 KRT18 LOC653888 LY96 NCK1 NCK2 NCL OCLN PRKCA RHOA ROCK1 ROCK2 TLR4 TLR5 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3D TUBA3E TUBA4A TUBA8 TUBAL3 TUBB TUBB1 TUBB2A TUBB2B TUBB2C TUBB3 TUBB4 TUBB4Q TUBB6 TUBB8 WAS WASL YWHAQ YWHAZ hsa05131 Shigellosis 646048 646821 ABL1 ACTB ACTG1 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 ARPC5L ATG5 BTRC CD44 CDC42 CHUK CRK CRKL CSK CTTN DIAPH1 DOCK1 ELMO1 FBXW11 HCLS1 IKBKB IKBKG IL8 ITGA5 ITGB1 LOC653888 MAD2L2 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK8 MAPK9 NFKB1 NFKBIA NFKBIB NOD1 NOD2 PFN1 PFN2 PFN3 PFN4 RAC1 RELA RHOG RIPK2 ROCK1 ROCK2 U2AF1 UBE2D2 VCL WAS WASF1 WASF2 WASL hsa05140 Leishmaniasis 100294318 C3 CR1 CYBA ELK1 FCGR1A FCGR2A FCGR2C FCGR3A FCGR3B FOS HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 IFNG IFNGR1 IFNGR2 IL10 IL12A IL12B IL1A IL1B IL4 IRAK1 IRAK4 ITGA4 ITGAM ITGB1 ITGB2 JAK1 JAK2 JUN LOC100133583 MAP3K7 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MARCKSL1 MYD88 NCF1 NCF2 NCF4 NFKB1 NFKBIA NFKBIB NOS2 PRKCB PTGS2 PTPN6 RELA STAT1 TAB1 TAB2 TGFB1 TGFB2 TGFB3 TLR2 TLR4 TNF TRAF6 hsa05142 Chagas disease ACE ADCY1 AKT1 AKT2 AKT3 BDKRB2 C1QA C1QB C1QC C3 CALR CASP8 CCL2 CCL3 CCL3L1 CCL3L3 CCL5 CD247 CD3D CD3E CD3G CFLAR CHUK FADD FAS FASLG FOS GNA11 GNA14 GNA15 GNAI1 GNAI2 GNAI3 GNAL GNAO1 GNAQ GNAS IFNB1 IFNG IFNGR1 IFNGR2 IKBKB IKBKG IL10 IL12A IL12B IL1B IL2 IL6 IL8 IRAK1 IRAK4 JUN MAP2K4 MAPK1 MAPK10 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MAPK8 MAPK9 MYD88 NFKB1 NFKBIA NOS2 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCB1 PLCB2 PLCB3 PLCB4 PPP2CA PPP2CB PPP2R1A PPP2R1B PPP2R2A PPP2R2B PPP2R2C PPP2R2D RELA SERPINE1 SMAD2 SMAD3 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TICAM1 TLR2 TLR4 TLR6 TLR9 TNF TNFRSF1A TRAF6 hsa05144 Malaria CCL2 CD36 CD40 CD40LG CD81 COMP CR1 CSF3 DARC GYPA GYPB GYPC HBA1 HBA2 HBB HBD HGF ICAM1 IFNG IL10 IL12A IL18 IL1B IL6 IL8 ITGAL ITGB2 KLRB1 KLRK1 LRP1 MET MYD88 PECAM1 SDC1 SDC2 SDC3 SDC4 SELE SELP TGFB1 TGFB2 TGFB3 THBS1 THBS2 THBS3 THBS4 TLR2 TLR4 TLR9 TNF VCAM1 hsa05146 Amoebiasis ACTN1 ACTN2 ACTN3 ACTN4 ADCY1 ARG1 ARG2 C8A C8B C8G C9 CASP3 CD14 CD1D COL11A1 COL11A2 COL1A1 COL1A2 COL2A1 COL3A1 COL4A1 COL4A2 COL4A4 COL4A6 COL5A1 COL5A2 COL5A3 CSF2 CTSG CXCL1 FN1 GNA11 GNA14 GNA15 GNAL GNAQ GNAS HSPB1 IFNG IL10 IL12A IL12B IL1B IL1R1 IL1R2 IL6 IL8 ITGAM ITGB2 LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 MUC2 NFKB1 NOS2 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCB1 PLCB2 PLCB3 PLCB4 PRKACA PRKACB PRKACG PRKCA PRKCB PRKCG PRKX PTK2 RAB5A RAB5B RAB5C RAB7A RAB7B RELA SERPINB1 SERPINB10 SERPINB13 SERPINB2 SERPINB3 SERPINB4 SERPINB6 SERPINB9 TGFB1 TGFB2 TGFB3 TLR2 TLR4 TNF VCL hsa05200 Pathways in cancer 652671 652799 ABL1 AKT1 AKT2 AKT3 APC APC2 APPL1 AR ARAF ARNT ARNT2 AXIN1 AXIN2 BAD BAX BCL2 BCL2L1 BCR BID BIRC2 BIRC3 BIRC5 BMP2 BMP4 BRAF BRCA2 CASP3 CASP8 CASP9 CBL CBLB CBLC CCDC6 CCNA1 CCND1 CCNE1 CCNE2 CDC42 CDH1 CDK2 CDK4 CDK6 CDKN1A CDKN1B CDKN2A CDKN2B CEBPA CHUK CKS1B COL4A1 COL4A2 COL4A4 COL4A6 CREBBP CRK CRKL CSF1R CSF2RA CSF3R CTBP1 CTBP2 CTNNA1 CTNNA2 CTNNA3 CTNNB1 CUL2 CYCS DAPK1 DAPK2 DAPK3 DCC DVL1 DVL2 DVL3 E2F1 E2F2 E2F3 EGF EGFR EGLN1 EGLN2 EGLN3 EP300 EPAS1 ERBB2 ETS1 FADD FAS FASLG FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR2 FGFR3 FH FIGF FLT3 FLT3LG FN1 FOS FOXO1 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GLI1 GLI2 GLI3 GRB2 GSK3B GSTP1 HDAC1 HDAC2 HGF HHIP HIF1A HRAS HSP90AA1 HSP90AB1 HSP90B1 IGF1 IGF1R IKBKB IKBKG IL6 IL8 ITGA2 ITGA2B ITGA3 ITGA6 ITGAV ITGB1 JAK1 JUN JUP KIT KITLG KLK3 KRAS LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 LEF1 LOC652346 MAP2K1 MAP2K2 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MAX MDM2 MECOM MET MITF MLH1 MMP1 MMP2 MMP9 MSH2 MSH3 MSH6 MTOR MYC NCOA4 NFKB1 NFKB2 NFKBIA NKX3-1 NOS2 NRAS NTRK1 PAX8 PDGFA PDGFB PDGFRA PDGFRB PGF PIAS1 PIAS2 PIAS3 PIAS4 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCG1 PLCG2 PLD1 PML PPARD PPARG PRKCA PRKCB PRKCG PTCH1 PTCH2 PTEN PTGS2 PTK2 RAC1 RAC2 RAC3 RAD51 RAF1 RALA RALB RALBP1 RALGDS RARA RARB RASSF1 RASSF5 RB1 RBX1 RELA RET RHOA RUNX1 RUNX1T1 RXRA RXRB RXRG SHH SKP2 SLC2A1 SMAD2 SMAD3 SMAD4 SMO SOS1 SOS2 SPI1 STAT1 STAT3 STAT5A STAT5B STK36 STK4 SUFU TCEB1 TCEB2 TCF7 TCF7L1 TCF7L2 TFG TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TP53 TPM3 TPR TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 VEGFA VEGFB VEGFC VHL WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B XIAP ZBTB16 hsa05210 Colorectal cancer AKT1 AKT2 AKT3 APC APC2 APPL1 ARAF AXIN1 AXIN2 BAD BAX BCL2 BIRC5 BRAF CASP3 CASP9 CCND1 CTNNB1 CYCS DCC FOS GSK3B JUN KRAS LEF1 MAP2K1 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 MLH1 MSH2 MSH3 MSH6 MYC PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 RAC1 RAC2 RAC3 RAF1 RALGDS RHOA SMAD2 SMAD3 SMAD4 TCF7 TCF7L1 TCF7L2 TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TP53 hsa05211 Renal cell carcinoma AKT1 AKT2 AKT3 ARAF ARNT ARNT2 BRAF CDC42 CREBBP CRK CRKL CUL2 EGLN1 EGLN2 EGLN3 EP300 EPAS1 ETS1 FH FIGF FLCN GAB1 GRB2 HGF HIF1A HRAS JUN KRAS MAP2K1 MAP2K2 MAPK1 MAPK3 MET NRAS PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PDGFB PGF PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PTPN11 RAC1 RAF1 RAP1A RAP1B RAPGEF1 RBX1 SLC2A1 SOS1 SOS2 TCEB1 TCEB2 TGFA TGFB1 TGFB2 TGFB3 VEGFA VEGFB VEGFC VHL hsa05212 Pancreatic cancer AKT1 AKT2 AKT3 ARAF ARHGEF6 BAD BCL2L1 BRAF BRCA2 CASP9 CCND1 CDC42 CDK4 CDK6 CDKN2A CHUK E2F1 E2F2 E2F3 EGF EGFR ERBB2 FIGF IKBKB IKBKG JAK1 KRAS MAP2K1 MAPK1 MAPK10 MAPK3 MAPK8 MAPK9 NFKB1 PGF PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLD1 RAC1 RAC2 RAC3 RAD51 RAF1 RALA RALB RALBP1 RALGDS RB1 RELA SMAD2 SMAD3 SMAD4 STAT1 STAT3 TGFA TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TP53 VEGFA VEGFB VEGFC hsa05213 Endometrial cancer AKT1 AKT2 AKT3 APC APC2 ARAF AXIN1 AXIN2 BAD BRAF CASP9 CCND1 CDH1 CTNNA1 CTNNA2 CTNNA3 CTNNB1 EGF EGFR ELK1 ERBB2 FOXO3 GRB2 GSK3B HRAS ILK KRAS LEF1 MAP2K1 MAP2K2 MAPK1 MAPK3 MLH1 MYC NRAS PDPK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PTEN RAF1 SOS1 SOS2 TCF7 TCF7L1 TCF7L2 TP53 hsa05214 Glioma AKT1 AKT2 AKT3 ARAF BRAF CALM1 CALM2 CALM3 CALML3 CALML5 CALML6 CAMK2A CAMK2B CAMK2D CAMK2G CCND1 CDK4 CDK6 CDKN1A CDKN2A E2F1 E2F2 E2F3 EGF EGFR GRB2 HRAS IGF1 IGF1R KRAS MAP2K1 MAP2K2 MAPK1 MAPK3 MDM2 MTOR NRAS PDGFA PDGFB PDGFRA PDGFRB PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCG1 PLCG2 PRKCA PRKCB PRKCG PTEN RAF1 RB1 SHC1 SHC2 SHC3 SHC4 SOS1 SOS2 TGFA TP53 hsa05215 Prostate cancer AKT1 AKT2 AKT3 AR ARAF ATF4 BAD BCL2 BRAF CASP9 CCND1 CCNE1 CCNE2 CDK2 CDKN1A CDKN1B CHUK CREB1 CREB3 CREB3L1 CREB3L2 CREB3L3 CREB3L4 CREB5 CREBBP CTNNB1 E2F1 E2F2 E2F3 EGF EGFR EP300 ERBB2 FGFR1 FGFR2 FOXO1 GRB2 GSK3B GSTP1 HRAS HSP90AA1 HSP90AB1 HSP90B1 IGF1 IGF1R IKBKB IKBKG INS INSRR KLK3 KRAS LEF1 MAP2K1 MAP2K2 MAPK1 MAPK3 MDM2 MTOR NFKB1 NFKBIA NKX3-1 NRAS PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PDPK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PTEN RAF1 RB1 RELA SOS1 SOS2 SRD5A2 TCF7 TCF7L1 TCF7L2 TGFA TP53 hsa05216 Thyroid cancer BRAF CCDC6 CCND1 CDH1 CTNNB1 HRAS KRAS LEF1 MAP2K1 MAP2K2 MAPK1 MAPK3 MYC NCOA4 NRAS NTRK1 PAX8 PPARG RET RXRA RXRB RXRG TCF7 TCF7L1 TCF7L2 TFG TP53 TPM3 TPR hsa05217 Basal cell carcinoma APC APC2 AXIN1 AXIN2 BMP2 BMP4 CTNNB1 DVL1 DVL2 DVL3 FZD1 FZD10 FZD2 FZD3 FZD4 FZD5 FZD6 FZD7 FZD8 FZD9 GLI1 GLI2 GLI3 GSK3B HHIP LEF1 PTCH1 PTCH2 SHH SMO STK36 SUFU TCF7 TCF7L1 TCF7L2 TP53 WNT1 WNT10A WNT10B WNT11 WNT16 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B hsa05218 Melanoma AKT1 AKT2 AKT3 ARAF BAD BRAF CCND1 CDH1 CDK4 CDK6 CDKN1A CDKN2A E2F1 E2F2 E2F3 EGF EGFR FGF1 FGF10 FGF11 FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF21 FGF22 FGF23 FGF3 FGF4 FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 HGF HRAS IGF1 IGF1R KRAS MAP2K1 MAP2K2 MAPK1 MAPK3 MDM2 MET MITF NRAS PDGFA PDGFB PDGFC PDGFD PDGFRA PDGFRB PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PTEN RAF1 RB1 TP53 hsa05219 Bladder cancer ARAF BRAF CCND1 CDH1 CDK4 CDKN1A CDKN2A DAPK1 DAPK2 DAPK3 E2F1 E2F2 E2F3 EGF EGFR ERBB2 FGFR3 FIGF HRAS IL8 KRAS MAP2K1 MAP2K2 MAPK1 MAPK3 MDM2 MMP1 MMP2 MMP9 MYC NRAS PGF RAF1 RASSF1 RB1 RPS6KA5 THBS1 TP53 TYMP VEGFA VEGFB VEGFC hsa05220 Chronic myeloid leukemia ABL1 AKT1 AKT2 AKT3 ARAF BAD BCL2L1 BCR BRAF CBL CBLB CBLC CCND1 CDK4 CDK6 CDKN1A CDKN1B CDKN2A CHUK CRK CRKL CTBP1 CTBP2 E2F1 E2F2 E2F3 GAB2 GRB2 HDAC1 HDAC2 HRAS IKBKB IKBKG KRAS MAP2K1 MAP2K2 MAPK1 MAPK3 MDM2 MECOM MYC NFKB1 NFKBIA NRAS PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PTPN11 RAF1 RB1 RELA RUNX1 SHC1 SHC2 SHC3 SHC4 SMAD3 SMAD4 SOS1 SOS2 STAT5A STAT5B TGFB1 TGFB2 TGFB3 TGFBR1 TGFBR2 TP53 hsa05221 Acute myeloid leukemia 652671 652799 AKT1 AKT2 AKT3 ARAF BAD BRAF CCNA1 CCND1 CEBPA CHUK EIF4EBP1 FLT3 GRB2 HRAS IKBKB IKBKG JUP KIT KRAS LEF1 LOC652346 MAP2K1 MAP2K2 MAPK1 MAPK3 MTOR MYC NFKB1 NRAS PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PIM1 PIM2 PML PPARD RAF1 RARA RELA RPS6KB1 RPS6KB2 RUNX1 RUNX1T1 SOS1 SOS2 SPI1 STAT3 STAT5A STAT5B TCF7 TCF7L1 TCF7L2 ZBTB16 hsa05222 Small cell lung cancer AKT1 AKT2 AKT3 APAF1 BCL2 BCL2L1 BIRC2 BIRC3 CASP9 CCND1 CCNE1 CCNE2 CDK2 CDK4 CDK6 CDKN1B CDKN2B CHUK CKS1B COL4A1 COL4A2 COL4A4 COL4A6 CYCS E2F1 E2F2 E2F3 FHIT FN1 IKBKB IKBKG ITGA2 ITGA2B ITGA3 ITGA6 ITGAV ITGB1 LAMA1 LAMA2 LAMA3 LAMA4 LAMA5 LAMB1 LAMB2 LAMB3 LAMB4 LAMC1 LAMC2 LAMC3 MAX MYC NFKB1 NFKBIA NOS2 PIAS1 PIAS2 PIAS3 PIAS4 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PTEN PTGS2 PTK2 RARB RB1 RELA RXRA RXRB RXRG SKP2 TP53 TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 XIAP hsa05223 Non-small cell lung cancer AKT1 AKT2 AKT3 ARAF BAD BRAF CASP9 CCND1 CDK4 CDK6 CDKN2A E2F1 E2F2 E2F3 EGF EGFR ERBB2 FHIT FOXO3 GRB2 HRAS KRAS MAP2K1 MAP2K2 MAPK1 MAPK3 NRAS PDPK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PIK3R5 PLCG1 PLCG2 PRKCA PRKCB PRKCG RAF1 RARB RASSF1 RASSF5 RB1 RXRA RXRB RXRG SOS1 SOS2 STK4 TGFA TP53 hsa05310 Asthma 100294318 CCL11 CD40 CD40LG EPX FCER1A FCER1G HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 IL10 IL13 IL3 IL4 IL5 IL9 LOC100133583 MS4A2 PRG2 RNASE3 TNF hsa05320 Autoimmune thyroid disease 100294318 CD28 CD40 CD40LG CD80 CD86 CGA CTLA4 FAS FASLG GZMB HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-E HLA-F HLA-G IFNA1 IFNA10 IFNA13 IFNA14 IFNA16 IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7 IFNA8 IL10 IL2 IL4 IL5 LOC100133583 LOC652614 PRF1 TG TPO TSHB TSHR hsa05322 Systemic lupus erythematosus 100294318 ACTN1 ACTN2 ACTN3 ACTN4 C1QA C1QB C1QC C1R C1S C2 C3 C4A C4B C5 C6 C7 C8A C8B C8G C9 CD28 CD40 CD40LG CD80 CD86 CTSG ELANE FCGR1A FCGR2A FCGR2B FCGR2C FCGR3A FCGR3B GRIN2A GRIN2B H2AFB1 H2AFB2 H2AFB3 H2AFJ H2AFV H2AFX H2AFY H2AFY2 H2AFZ H2BFM H2BFWT H3F3A H3F3B H3F3C HIST1H2AA HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2AG HIST1H2AH HIST1H2AI HIST1H2AJ HIST1H2AK HIST1H2AL HIST1H2AM HIST1H2BA HIST1H2BB HIST1H2BC HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2BI HIST1H2BJ HIST1H2BK HIST1H2BL HIST1H2BM HIST1H2BN HIST1H2BO HIST1H3A HIST1H3B HIST1H3C HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HIST1H4A HIST1H4B HIST1H4C HIST1H4D HIST1H4E HIST1H4F HIST1H4G HIST1H4H HIST1H4I HIST1H4J HIST1H4K HIST1H4L HIST2H2AA3 HIST2H2AA4 HIST2H2AB HIST2H2AC HIST2H2BE HIST2H2BF HIST2H3A HIST2H3C HIST2H3D HIST2H4A HIST2H4B HIST3H2A HIST3H2BB HIST3H3 HIST4H4 HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 IFNG IL10 LOC100133583 LOC340096 LOC391769 LOC644950 LOC651868 SNRPB SNRPD1 SNRPD3 SSB TNF TRIM21 TROVE2 hsa05330 Allograft rejection 100294318 CD28 CD40 CD40LG CD80 CD86 FAS FASLG GZMB HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-E HLA-F HLA-G IFNG IL10 IL12A IL12B IL2 IL4 IL5 LOC100133583 LOC652614 PRF1 TNF hsa05332 Graft-versus-host disease 100294318 CD28 CD80 CD86 FAS FASLG GZMB HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-E HLA-F HLA-G IFNG IL1A IL1B IL2 IL6 KIR2DL1 KIR2DL2 KIR2DL3 KIR2DL5A KIR3DL1 KIR3DL2 KLRC1 KLRD1 LOC100133583 LOC652614 PRF1 TNF hsa05340 Primary immunodeficiency ADA AICDA AIRE BLNK BTK CD19 CD3D CD3E CD4 CD40 CD40LG CD79A CD8A CD8B CIITA DCLRE1C ICOS IGLL1 IKBKG IL2RG IL7R JAK3 LCK PTPRC RAG1 RAG2 RFX5 RFXANK RFXAP TAP1 TAP2 TNFRSF13B TNFRSF13C UNG ZAP70 hsa05410 Hypertrophic cardiomyopathy (HCM) 646048 646821 ACE ACTB ACTC1 ACTG1 ATP2A2 CACNA1C CACNA1D CACNA1F CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 DAG1 DES DMD EMD IGF1 IL6 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 LAMA2 LMNA MYBPC3 MYH6 MYH7 MYL2 MYL3 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RYR2 SGCA SGCB SGCD SGCG SLC8A1 TGFB1 TGFB2 TGFB3 TNF TNNC1 TNNI3 TNNT2 TPM1 TPM2 TPM3 TPM4 TTN hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 646048 646821 ACTB ACTG1 ACTN1 ACTN2 ACTN3 ACTN4 ATP2A2 CACNA1C CACNA1D CACNA1F CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 CDH2 CTNNA1 CTNNA2 CTNNA3 CTNNB1 DAG1 DES DMD DSC2 DSG2 DSP EMD GJA1 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 JUP LAMA2 LEF1 LMNA PKP2 RYR2 SGCA SGCB SGCD SGCG SLC8A1 TCF7 TCF7L1 TCF7L2 hsa05414 Dilated cardiomyopathy 646048 646821 ACTB ACTC1 ACTG1 ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY7 ADCY8 ADCY9 ADRB1 ATP2A2 CACNA1C CACNA1D CACNA1F CACNA1S CACNA2D1 CACNA2D2 CACNA2D3 CACNA2D4 CACNB1 CACNB2 CACNB3 CACNB4 CACNG1 CACNG2 CACNG3 CACNG4 CACNG5 CACNG6 CACNG7 CACNG8 DAG1 DES DMD EMD GNAS IGF1 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA7 ITGA8 ITGA9 ITGAV ITGB1 ITGB3 ITGB4 ITGB5 ITGB6 ITGB7 ITGB8 LAMA2 LMNA MYBPC3 MYH6 MYH7 MYL2 MYL3 PLN PRKACA PRKACB PRKACG PRKX RYR2 SGCA SGCB SGCD SGCG SLC8A1 TGFB1 TGFB2 TGFB3 TNF TNNC1 TNNI3 TNNT2 TPM1 TPM2 TPM3 TPM4 TTN hsa05416 Viral myocarditis 100294318 646048 646821 ABL1 ABL2 ACTB ACTG1 BID CASP3 CASP8 CASP9 CAV1 CCND1 CD28 CD40 CD40LG CD55 CD80 CD86 CXADR CYCS DAG1 DMD EIF4G1 EIF4G2 EIF4G3 FYN HLA-A HLA-B HLA-C HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 HLA-E HLA-F HLA-G ICAM1 ITGAL ITGB2 LAMA2 LOC100133583 LOC652614 MYH1 MYH10 MYH11 MYH13 MYH14 MYH15 MYH2 MYH3 MYH4 MYH6 MYH7 MYH7B MYH8 MYH9 PRF1 RAC1 RAC2 RAC3 SGCA SGCB SGCD SGCG