data type: SNP
method: ZSCORE
K: 2
cutoff: 0.05
tolerance: 0%
Genes with the 1st to the k-th largest or smallest p-values: Exclude
Take common log and negated the p-values of genes: Yes
set name | gene count | set size | z-score | p-value | corrected p-value | FDR | gene symbols | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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hsa04360 (boxplot) | 121 | 130 | 4.608610506643561 | 2.0268445264370882E-6 | 3.8712730454948385E-4 | 0.0 | NTN1 5.0228 | UNC5C 3.8938 | SEMA3A 3.7073 | LRRC4C 3.6415 | ABLIM2 3.3292 | EPHA6 3.0747 | SLIT3 3.0397 | DCC 2.9809 | NTNG1 2.9570 | NTN4 2.8904 | ABLIM1 2.8775 | SEMA4C 2.8327 | RAC2 2.8280 | EFNA5 2.7908 | EPHA5 2.7696 | PTK2 2.7491 | ITGB1 2.7206 | SEMA5B 2.7206 | ABLIM3 2.7014 | UNC5D 2.6874 | PLXNB1 2.6747 | RAC1 2.6726 | ROBO2 2.6682 | RASA1 2.6584 | SLIT2 2.5546 | RHOA 2.5129 | SEMA5A 2.5084 | EPHB1 2.4432 | NFATC2 2.3660 | FYN 2.2385 | NFATC3 2.2123 | SEMA6A 2.1927 | MAPK1 2.1844 | EPHB2 2.1441 | ROBO1 2.1315 | SLIT1 2.0843 | NFAT5 2.0659 | ROCK2 2.0579 | CXCL12 2.0554 | EPHA8 2.0542 | SEMA6D 2.0540 | PLXNC1 2.0343 | PAK7 2.0233 | GNAI3 2.0223 | SEMA3G 2.0141 | SRGAP3 1.9987 | EPHA1 1.9755 | PPP3CA 1.9062 | PLXNA2 1.8371 | SEMA7A 1.8286 | CDC42 1.8213 | NRP1 1.8030 | EPHA4 1.7778 | RHOD 1.7762 | EPHA3 1.7716 | NFATC1 1.7678 | PAK6 1.7667 | NGEF 1.7572 | HRAS 1.7462 | ARHGEF12 1.7452 | CDK5 1.7064 | EPHB3 1.7027 | SEMA6B 1.6979 | RND1 1.6975 | EPHA2 1.6880 | MAPK3 1.6641 | EPHA7 1.6596 | CHP2 1.6574 | PPP3R2 1.6507 | EFNB3 1.6494 | KRAS 1.6419 | UNC5B 1.6396 | PAK1 1.6191 | GNAI1 1.6096 | PPP3R1 1.6073 | SEMA3C 1.6071 | DPYSL5 1.5896 | FES 1.5662 | SEMA3E 1.5638 | GSK3B 1.5188 | SEMA6C 1.5183 | ABL1 1.5088 | SEMA4G 1.4623 | NCK2 1.4406 | RAC3 1.4192 | MET 1.3873 | SRGAP1 1.3691 | EPHB4 1.3517 | PAK2 1.3442 | SEMA3D 1.3311 | SEMA4A 1.3161 | EFNB2 1.2812 | ROCK1 1.2802 | SEMA4D 1.2725 | PPP3CC 1.2662 | PLXNB2 1.2647 | EFNA2 1.2352 | CFL2 1.1942 | DPYSL2 1.1596 | PLXNA1 1.1495 | SEMA4F 1.1265 | CFL1 1.0981 | NFATC4 1.0953 | SEMA3F 1.0747 | SEMA4B 1.0659 | PAK4 1.0641 | EPHB6 1.0603 | RGS3 1.0510 | ROBO3 1.0492 | SRGAP2 0.9500 | CXCR4 0.9401 | UNC5A 0.9355 | LIMK2 0.9101 | LIMK1 0.8533 | NRAS 0.7783 | NCK1 0.6959 | NTN3 0.6718 | EFNA3 0.6486 | EFNA4 | PPP3CB 0.4679 | GNAI2 0.3699 | SEMA3B | EFNA1 0.3606 | Axon guidance | CHP | EFNB1 | L1CAM | PAK3 | PLXNA3 | PLXNB3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05412 (boxplot) | 71 | 77 | 4.400197028436345 | 5.407631660903078E-6 | 5.16428823616244E-4 | 0.0 | RYR2 4.0432 | SLC8A1 3.8778 | ACTB 3.7300 | CACNB2 3.4475 | CTNNA2 3.2208 | CACNA1C 3.1697 | ACTN1 3.0707 | ITGA9 2.9512 | CACNA2D3 2.9129 | DSP 2.9097 | SGCG 2.8471 | DAG1 2.8456 | CACNA1S 2.7820 | ITGB1 2.7206 | CACNG2 2.7033 | SGCD 2.6291 | TCF7L2 2.5921 | ITGA8 2.4888 | ACTG1 2.4632 | CACNB4 2.3591 | ITGA2B 2.3301 | ITGAV 2.3143 | CACNA2D4 2.2869 | ACTN3 2.2041 | CTNNA3 2.1832 | CACNA1D 2.1133 | ITGA2 2.1044 | CACNG7 2.0613 | CACNG8 2.0613 | JUP 2.0506 | CDH2 2.0337 | TCF7L1 1.9555 | CACNG3 1.8755 | DSC2 1.8573 | ITGA1 1.8523 | ITGA11 1.8142 | CACNA2D1 1.7625 | SGCA 1.7333 | ITGB8 1.7109 | CACNB3 1.6975 | LAMA2 1.6851 | PKP2 1.6774 | ITGB5 1.6653 | ITGA6 1.6515 | CACNG6 | ITGA10 1.6014 | ITGB4 1.5923 | CACNG4 1.4950 | ITGA3 1.4609 | DSG2 1.4600 | DES 1.4059 | CACNG5 1.3384 | ITGB6 1.2993 | ACTN2 1.2903 | ITGB7 1.2638 | ITGB3 1.2237 | CACNG1 1.2169 | GJA1 1.1360 | TCF7 1.1162 | ITGA7 1.1013 | CACNB1 1.0777 | ACTN4 1.0023 | CTNNA1 0.9825 | LMNA 0.9488 | CTNNB1 0.9144 | CACNA2D2 0.8993 | LEF1 0.8952 | ITGA4 0.8908 | ITGA5 0.8523 | ATP2A2 0.5605 | SGCB 0.5305 | DMD 0.3468 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 646048 | 646821 | CACNA1F | EMD | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04510 (boxplot) | 191 | 202 | 4.150298824791389 | 1.6602074752514184E-5 | 0.001056998759243403 | 0.0 | RELN 4.5574 | ACTB 3.7300 | COL4A2 3.5427 | MYL12A 3.3308 | MYL12B | LAMC3 3.2308 | PIK3R5 3.1433 | ACTN1 3.0707 | BAD 3.0689 | DOCK1 3.0297 | PRKCB 3.0263 | FLNB 2.9801 | ITGA9 2.9512 | COL4A1 2.9190 | BCL2 2.8962 | TNR 2.8416 | RAC2 2.8280 | PRKCA 2.7739 | PTK2 2.7491 | ITGB1 2.7206 | RAC1 2.6726 | SHC4 2.6119 | MAPK8 2.6033 | IGF1R 2.5914 | MAP2K1 2.5626 | PGF 2.5613 | MAPK10 2.5394 | RHOA 2.5129 | ITGA8 2.4888 | VEGFB 2.4840 | PDGFC 2.4824 | ACTG1 2.4632 | BCAR1 2.4612 | VAV1 2.4525 | PIP5K1C 2.4349 | COMP 2.3919 | TNC 2.3900 | EGFR 2.3734 | VAV2 2.3528 | LAMC1 2.3490 | ITGA2B 2.3301 | ITGAV 2.3143 | FLT1 2.3050 | FYN 2.2385 | CAPN2 2.2334 | TNXB 2.2202 | LAMA3 2.2199 | ACTN3 2.2041 | LAMA1 2.1908 | PARVA 2.1872 | MAPK1 2.1844 | VASP 2.1552 | COL11A2 2.1076 | FLNC 2.1069 | ITGA2 2.1044 | CAV2 2.0696 | ROCK2 2.0579 | RASGRF1 2.0539 | PDGFA 2.0484 | HGF 2.0308 | PAK7 2.0233 | COL6A2 2.0219 | RAPGEF1 1.9957 | VAV3 1.9834 | EGF 1.9813 | TLN1 1.9662 | LAMB4 1.9602 | CHAD 1.9590 | PDGFD 1.9570 | MYL5 1.9355 | IGF1 1.9296 | PARVB 1.8877 | COL4A4 1.8841 | COL5A1 1.8811 | LAMA5 1.8536 | BIRC2 1.8533 | PRKCG 1.8526 | ITGA1 1.8523 | COL2A1 1.8447 | PDGFB 1.8438 | CDC42 1.8213 | CAV1 1.8147 | ITGA11 1.8142 | COL6A6 1.7929 | VWF 1.7765 | PAK6 1.7667 | HRAS 1.7462 | COL1A1 1.7333 | ZYX 1.7305 | PIK3CD 1.7138 | ITGB8 1.7109 | AKT1 1.7014 | PARVG 1.7007 | LAMA2 1.6851 | COL11A1 1.6817 | MYLK 1.6757 | TLN2 1.6743 | MYL7 1.6682 | ITGB5 1.6653 | MAPK3 1.6641 | ITGA6 1.6515 | PAK1 1.6191 | TNN 1.6158 | SRC 1.6146 | LAMC2 1.6114 | CCND2 1.6022 | ITGA10 1.6014 | SOS2 1.5974 | ITGB4 1.5923 | IBSP 1.5820 | BRAF 1.5539 | COL6A3 1.5530 | VCL 1.5498 | BIRC3 1.5424 | FLT4 1.5361 | GSK3B 1.5188 | PDGFRA 1.4972 | PPP1CC 1.4919 | SHC3 1.4919 | COL3A1 1.4878 | PIK3CA 1.4804 | LAMB3 1.4777 | PDGFRB 1.4665 | ITGA3 1.4609 | SHC2 1.4331 | RAC3 1.4192 | CRK 1.4166 | PIK3R2 1.4143 | CAV3 1.4085 | MAPK9 1.4013 | CCND1 1.4000 | COL1A2 1.3917 | MET 1.3873 | PIK3CB 1.3849 | PAK2 1.3442 | ITGB6 1.2993 | ACTN2 1.2903 | MYLK3 1.2840 | ROCK1 1.2802 | COL6A1 1.2798 | RAP1A 1.2747 | LAMA4 1.2720 | MYL9 1.2691 | COL5A3 1.2647 | ITGB7 1.2638 | LAMB1 1.2559 | COL5A2 1.2531 | DIAPH1 1.2479 | FN1 1.2328 | RAF1 1.2321 | ARHGAP5 1.2312 | ITGB3 1.2237 | THBS4 1.2117 | PIK3R1 1.1894 | CCND3 1.1468 | VEGFA 1.1459 | PIK3CG 1.1284 | PPP1R12A 1.1124 | ITGA7 1.1013 | THBS2 1.0954 | MYL10 1.0953 | RAP1B 1.0677 | MYL2 1.0664 | PAK4 1.0641 | VEGFC 1.0533 | KDR 1.0514 | MYLK2 1.0363 | CRKL 1.0292 | MYLPF 1.0237 | ACTN4 1.0023 | AKT3 0.9935 | LAMB2 0.9751 | JUN 0.9706 | ERBB2 0.9686 | PXN 0.9662 | CTNNB1 0.9144 | PDPK1 0.9045 | AKT2 0.9017 | PTEN 0.8976 | ITGA4 0.8908 | PPP1CA 0.8778 | PPP1CB 0.8684 | PIK3R3 0.8554 | ITGA5 0.8523 | GRB2 0.8222 | VTN 0.8058 | ILK 0.7126 | THBS3 0.6651 | SHC1 0.6411 | SOS1 0.6101 | SPP1 0.5102 | THBS1 0.4991 | Focal adhesion | 646048 | 646821 | COL4A6 | ELK1 | FIGF | FLNA | GRLF1 | PAK3 | XIAP | |||||||||||||||
hsa04514 (boxplot) | 124 | 137 | 3.999085121883304 | 3.17939044666149E-5 | 0.0015181589382808613 | 0.0 | HLA-DQA1 4.6600 | HLA-DQB1 4.6600 | CNTNAP2 3.4198 | CDH4 3.4059 | SDC2 3.3426 | HLA-DRB1 3.2362 | CLDN20 3.0503 | CLDN5 3.0479 | SDC1 3.0466 | CLDN16 2.9594 | ITGA9 2.9512 | NCAM2 2.9090 | NEGR1 2.7547 | HLA-DRB5 2.7440 | ITGB1 2.7206 | NLGN1 2.6885 | HLA-DOB 2.6796 | ICAM2 2.6649 | PTPRM 2.6623 | HLA-B 2.6605 | NRXN3 2.6501 | PVRL3 2.6476 | NRXN2 2.6101 | MPZ 2.5436 | CD226 2.5417 | SDC4 2.5317 | GLG1 2.5223 | ITGA8 2.4888 | PTPRF 2.4880 | SELPLG 2.4235 | NCAM1 2.3600 | ITGB2 2.3293 | ITGAV 2.3143 | CNTN1 2.2524 | NEO1 2.1802 | SIGLEC1 2.1377 | NRCAM 2.1245 | VCAN 2.1196 | HLA-DOA 2.1076 | CDH2 2.0337 | CADM3 2.0237 | CADM1 2.0120 | CLDN22 2.0102 | CD80 2.0016 | PVRL1 2.0014 | VCAM1 1.9817 | CD6 1.9727 | HLA-DRA 1.9559 | CD40 1.9289 | NFASC 1.9252 | NRXN1 1.9194 | MPZL1 1.8983 | MADCAM1 1.8611 | CD22 1.8502 | CLDN14 1.8130 | JAM2 1.7762 | PVR 1.7421 | CLDN19 1.7298 | ITGB8 1.7109 | CLDN18 1.6972 | ITGA6 1.6515 | CLDN1 1.6284 | HLA-A 1.6214 | HLA-F 1.6214 | CLDN10 1.5844 | CD34 1.5772 | CD2 1.5530 | HLA-C 1.5498 | CDH1 1.5358 | HLA-DPA1 1.5330 | HLA-G 1.5274 | ALCAM 1.5261 | JAM3 1.5126 | PVRL2 1.5039 | ESAM 1.4708 | SDC3 1.4257 | MAG 1.4223 | CLDN17 1.4118 | HLA-DPB1 1.3901 | SPN 1.3788 | HLA-E 1.3786 | HLA-DMA 1.3629 | HLA-DMB | CDH5 1.3421 | CLDN8 1.3417 | ITGAL 1.3308 | CNTN2 1.3153 | CD8B 1.3019 | PDCD1LG2 1.2909 | HLA-DQA2 1.2857 | ITGB7 1.2638 | PECAM1 1.2503 | CDH15 1.2329 | CLDN11 1.2257 | CLDN23 1.2160 | ICOSLG 1.2155 | ITGAM 1.2111 | SELP 1.1915 | NLGN2 1.1778 | PTPRC 1.1688 | CD276 1.1675 | CLDN3 1.1649 | CDH3 1.1602 | CD274 1.1479 | SELL 1.1453 | OCLN 1.1211 | F11R 1.0618 | CD8A 0.9889 | ICAM1 0.9880 | ICOS 0.9674 | CLDN4 0.9151 | PDCD1 0.9059 | CD28 0.8959 | ITGA4 0.8908 | CLDN7 0.8542 | CD86 0.8362 | CD58 0.7978 | CD4 0.7830 | SELE 0.7693 | ICAM3 0.7371 | CTLA4 0.6682 | HLA-DRB3 0.5719 | CNTNAP1 0.5471 | CLDN6 0.5071 | CLDN9 | CLDN15 0.4585 | Cell adhesion molecules (CAMs) | 100294318 | CD40LG | CD99 | CLDN2 | HLA-DRB4 | L1CAM | LOC100133583 | LOC652614 | NLGN3 | NLGN4X | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05414 (boxplot) | 86 | 93 | 3.967082063909324 | 3.637897274366697E-5 | 0.0015181589382808613 | 0.0 | ADCY9 4.0587 | RYR2 4.0432 | SLC8A1 3.8778 | ACTB 3.7300 | TGFB2 3.6070 | CACNB2 3.4475 | CACNA1C 3.1697 | ADCY2 2.9743 | ITGA9 2.9512 | CACNA2D3 2.9129 | SGCG 2.8471 | DAG1 2.8456 | CACNA1S 2.7820 | ITGB1 2.7206 | CACNG2 2.7033 | SGCD 2.6291 | PRKACG 2.6173 | ITGA8 2.4888 | ACTG1 2.4632 | CACNB4 2.3591 | ITGA2B 2.3301 | ITGAV 2.3143 | CACNA2D4 2.2869 | TTN 2.2689 | TNF 2.2219 | MYL3 2.1233 | CACNA1D 2.1133 | ITGA2 2.1044 | CACNG7 2.0613 | CACNG8 2.0613 | PRKACB 2.0477 | TNNC1 2.0141 | ADCY1 1.9897 | TPM2 1.9662 | IGF1 1.9296 | CACNG3 1.8755 | ITGA1 1.8523 | ADCY6 1.8202 | ITGA11 1.8142 | GNAS 1.7902 | TNNT2 1.7781 | ACTC1 1.7680 | CACNA2D1 1.7625 | ADCY8 1.7592 | SGCA 1.7333 | ITGB8 1.7109 | ADCY5 1.6975 | CACNB3 1.6975 | LAMA2 1.6851 | ITGB5 1.6653 | ITGA6 1.6515 | CACNG6 | ITGA10 1.6014 | ITGB4 1.5923 | TNNI3 1.5919 | CACNG4 1.4950 | TGFB1 1.4755 | ITGA3 1.4609 | DES 1.4059 | CACNG5 1.3384 | ITGB6 1.2993 | ITGB7 1.2638 | TPM4 1.2423 | ADRB1 1.2389 | ITGB3 1.2237 | CACNG1 1.2169 | MYH6 1.2039 | PRKACA 1.1632 | ITGA7 1.1013 | ADCY3 1.1011 | CACNB1 1.0777 | MYL2 1.0664 | MYBPC3 1.0532 | MYH7 1.0003 | ADCY4 0.9872 | LMNA 0.9488 | TPM3 0.9322 | PLN 0.9027 | TPM1 0.9024 | CACNA2D2 0.8993 | ITGA4 0.8908 | ITGA5 0.8523 | TGFB3 0.8111 | ADCY7 0.6048 | ATP2A2 0.5605 | SGCB 0.5305 | DMD 0.3468 | Dilated cardiomyopathy | 646048 | 646821 | CACNA1F | EMD | PRKX | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04530 (boxplot) | 128 | 135 | 3.8444754005002157 | 6.040530128148536E-5 | 0.0019229020907939505 | 0.0 | MPP5 6.8083 | PPP2R1A 4.3669 | MAGI2 4.2212 | ACTB 3.7300 | PRKCD 3.3826 | ZAK 3.3383 | MYL12A 3.3308 | MYL12B | CTNNA2 3.2208 | RAB3B 3.1115 | ACTN1 3.0707 | CLDN20 3.0503 | CLDN5 3.0479 | PRKCB 3.0263 | CLDN16 2.9594 | CDK4 2.7978 | PRKCZ 2.7757 | PRKCA 2.7739 | CRB3 2.7471 | MYH9 2.7326 | MYH13 2.7310 | SYMPK 2.6942 | MYH3 2.6392 | MYH11 2.6183 | EPB41L3 2.5674 | RHOA 2.5129 | ACTG1 2.4632 | PRKCE 2.4343 | MAGI1 2.3971 | PARD6G 2.2746 | EXOC4 2.2539 | MYH14 2.2453 | PPP2R2D 2.2275 | PPP2R2C 2.2143 | ACTN3 2.2041 | CTNNA3 2.1832 | TJP2 2.1614 | CSDA 2.1549 | MYH8 2.1503 | PPP2R2B 2.1274 | INADL 2.0463 | GNAI3 2.0223 | CLDN22 2.0102 | PRKCQ 1.9582 | MYL5 1.9355 | MYH15 1.9278 | HCLS1 1.9104 | MPDZ 1.8684 | PRKCG 1.8526 | CDC42 1.8213 | CLDN14 1.8130 | MAGI3 1.7807 | JAM2 1.7762 | HRAS 1.7462 | CLDN19 1.7298 | SPTAN1 1.7212 | PARD6B 1.7042 | AKT1 1.7014 | CLDN18 1.6972 | CSNK2A1 1.6824 | MYL7 1.6682 | KRAS 1.6419 | CLDN1 1.6284 | SRC 1.6146 | GNAI1 1.6096 | PARD3 1.5924 | MLLT4 1.5911 | CLDN10 1.5844 | PPP2R2A 1.5646 | EXOC3 1.5473 | MYH4 1.5321 | JAM3 1.5126 | PPP2R1B 1.4855 | PRKCH 1.4763 | YES1 1.4362 | CGN 1.4313 | PRKCI 1.4300 | RRAS2 1.4290 | CLDN17 1.4118 | MYH10 1.4107 | PPP2CA 1.3706 | CLDN8 1.3417 | ASH1L 1.3363 | LLGL1 1.3004 | ACTN2 1.2903 | MYL9 1.2691 | CSNK2B 1.2467 | EPB41L2 1.2440 | CLDN11 1.2257 | TJP1 1.2232 | CLDN23 1.2160 | MYH6 1.2039 | CLDN3 1.1649 | VAPA 1.1500 | OCLN 1.1211 | TJP3 1.1195 | MYL10 1.0953 | PARD6A 1.0943 | TJAP1 1.0849 | MYH2 1.0753 | MYL2 1.0664 | IGSF5 1.0653 | F11R 1.0618 | CTTN 1.0617 | MYH1 1.0547 | CSNK2A2 1.0512 | LLGL2 1.0510 | EPB41L1 1.0334 | EPB41 1.0299 | MYLPF 1.0237 | MRAS 1.0046 | ACTN4 1.0023 | MYH7 1.0003 | AKT3 0.9935 | CTNNA1 0.9825 | PPP2CB 0.9825 | RRAS 0.9650 | CLDN4 0.9151 | CTNNB1 0.9144 | AKT2 0.9017 | PTEN 0.8976 | CLDN7 0.8542 | MYH7B 0.8142 | NRAS 0.7783 | RAB13 0.7701 | AMOTL1 0.7352 | CLDN6 0.5071 | CLDN9 | CLDN15 0.4585 | GNAI2 0.3699 | Tight junction | 646048 | 646821 | CASK | CLDN2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04512 (boxplot) | 83 | 85 | 3.8327923283165335 | 6.334845252475851E-5 | 0.0019229020907939505 | 0.0 | RELN 4.5574 | COL4A2 3.5427 | CD47 3.5315 | SDC2 3.3426 | LAMC3 3.2308 | SDC1 3.0466 | HSPG2 2.9706 | ITGA9 2.9512 | COL4A1 2.9190 | DAG1 2.8456 | TNR 2.8416 | ITGB1 2.7206 | SV2B 2.6891 | SDC4 2.5317 | ITGA8 2.4888 | COMP 2.3919 | TNC 2.3900 | LAMC1 2.3490 | ITGA2B 2.3301 | GP6 2.3214 | ITGAV 2.3143 | TNXB 2.2202 | LAMA3 2.2199 | LAMA1 2.1908 | SV2C 2.1792 | COL11A2 2.1076 | ITGA2 2.1044 | COL6A2 2.0219 | LAMB4 1.9602 | CHAD 1.9590 | COL4A4 1.8841 | COL5A1 1.8811 | LAMA5 1.8536 | ITGA1 1.8523 | COL2A1 1.8447 | ITGA11 1.8142 | COL6A6 1.7929 | VWF 1.7765 | AGRN 1.7445 | SV2A 1.7380 | CD44 1.7373 | COL1A1 1.7333 | ITGB8 1.7109 | LAMA2 1.6851 | COL11A1 1.6817 | ITGB5 1.6653 | ITGA6 1.6515 | GP9 1.6196 | TNN 1.6158 | LAMC2 1.6114 | ITGA10 1.6014 | ITGB4 1.5923 | IBSP 1.5820 | COL6A3 1.5530 | GP5 1.5270 | COL3A1 1.4878 | LAMB3 1.4777 | ITGA3 1.4609 | SDC3 1.4257 | COL1A2 1.3917 | GP1BB 1.3523 | HMMR 1.3150 | ITGB6 1.2993 | COL6A1 1.2798 | LAMA4 1.2720 | COL5A3 1.2647 | ITGB7 1.2638 | LAMB1 1.2559 | COL5A2 1.2531 | FN1 1.2328 | ITGB3 1.2237 | THBS4 1.2117 | ITGA7 1.1013 | THBS2 1.0954 | LAMB2 0.9751 | CD36 0.9735 | ITGA4 0.8908 | ITGA5 0.8523 | VTN 0.8058 | GP1BA 0.6767 | THBS3 0.6651 | SPP1 0.5102 | THBS1 0.4991 | ECM-receptor interaction | COL4A6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04730 (boxplot) | 64 | 71 | 3.829364539794545 | 6.423728879390023E-5 | 0.0019229020907939505 | 0.0 | PPP2R1A 4.3669 | PLCB3 3.0689 | PRKG1 3.0481 | PLCB2 3.0466 | PRKCB 3.0263 | PRKG2 2.9686 | GUCY1A2 2.9322 | CACNA1A 2.9234 | ITPR1 2.8897 | PRKCA 2.7739 | LYN 2.7044 | ITPR2 2.6702 | NOS1 2.6267 | GNA12 2.6234 | IGF1R 2.5914 | MAP2K1 2.5626 | ITPR3 2.5571 | PLA2G2A 2.4585 | PLA2G4A 2.4025 | GRM1 2.3621 | MAPK1 2.1844 | PLCB1 2.1804 | GUCY1A3 2.0975 | GUCY1B3 | PLA2G5 2.0932 | GNA13 2.0279 | GNAI3 2.0223 | GNA11 2.0156 | GRID2 2.0063 | IGF1 1.9296 | PRKCG 1.8526 | GNAS 1.7902 | PLCB4 1.7585 | HRAS 1.7462 | MAPK3 1.6641 | KRAS 1.6419 | GNAI1 1.6096 | PLA2G10 1.5567 | BRAF 1.5539 | GRIA1 1.5071 | JMJD7-PLA2G4B 1.4984 | PLA2G4B | GRM5 1.4972 | PPP2R1B 1.4855 | GNAO1 1.4537 | RYR1 1.4385 | PPP2CA 1.3706 | GNAQ 1.3514 | PLA2G6 1.3336 | PLA2G2D 1.3238 | PLA2G4E 1.3187 | MAP2K2 1.3141 | PLA2G12B 1.2433 | CRH 1.2347 | RAF1 1.2321 | PLA2G2C 1.1830 | PLA2G2F | CRHR1 1.1318 | GNAZ 1.1011 | GRIA2 0.9944 | PPP2CB 0.9825 | PLA2G12A 0.9805 | PLA2G2E 0.8914 | PLA2G3 0.8557 | NRAS 0.7783 | PLA2G1B 0.7612 | GNAI2 0.3699 | Long-term depression | ARAF | C7orf16 | GRIA3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04810 (boxplot) | 198 | 217 | 3.6703035414316814 | 1.2113130416646634E-4 | 0.002570675455088341 | 0.0 | BAIAP2 3.8173 | ACTB 3.7300 | NCKAP1 3.5498 | FGF19 3.3729 | FGF14 3.3354 | MYL12A 3.3308 | MYL12B | PIK3R5 3.1433 | FGF23 3.0977 | ACTN1 3.0707 | TIAM2 3.0503 | DOCK1 3.0297 | ITGA9 2.9512 | IQGAP2 2.9431 | RDX 2.9219 | FGF3 2.8496 | RAC2 2.8280 | PTK2 2.7491 | CHRM3 2.7411 | MYH9 2.7326 | ITGB1 2.7206 | ITGAE 2.6828 | RAC1 2.6726 | GNA12 2.6234 | PIP5K1B 2.6173 | FGD3 2.5855 | MAP2K1 2.5626 | TIAM1 2.5449 | FGFR4 2.5137 | RHOA 2.5129 | SSH2 2.4987 | ITGA8 2.4888 | PDGFC 2.4824 | ACTG1 2.4632 | BCAR1 2.4612 | CYFIP1 2.4585 | VAV1 2.4525 | PIP5K1C 2.4349 | EGFR 2.3734 | FGF4 2.3650 | VAV2 2.3528 | ARHGEF4 2.3509 | PFN3 2.3497 | ITGA2B 2.3301 | ITGB2 2.3293 | ITGAV 2.3143 | FGF2 2.2467 | MYH14 2.2453 | FGF12 2.2433 | ACTN3 2.2041 | APC 2.2038 | FGFR2 2.1900 | MAPK1 2.1844 | SLC9A1 2.1139 | FGF18 2.1111 | FGF6 2.1109 | ITGA2 2.1044 | PIKFYVE 2.1044 | ARPC2 2.0718 | SCIN 2.0620 | ROCK2 2.0579 | PDGFA 2.0484 | FGF5 2.0384 | FGF9 2.0338 | GNA13 2.0279 | PAK7 2.0233 | ARHGEF1 2.0091 | ENAH 2.0045 | CYFIP2 1.9867 | VAV3 1.9834 | EGF 1.9813 | PDGFD 1.9570 | MYL5 1.9355 | ITGA1 1.8523 | PDGFB 1.8438 | FGF21 1.8435 | CDC42 1.8213 | ITGA11 1.8142 | GIT1 1.8058 | INSRR 1.7991 | CHRM1 1.7817 | NCKAP1L 1.7698 | PAK6 1.7667 | FGF1 1.7572 | FGF22 1.7491 | HRAS 1.7462 | ARHGEF12 1.7452 | PIP4K2B 1.7345 | PIK3CD 1.7138 | ITGB8 1.7109 | SSH1 1.7036 | ABI2 1.6951 | MYLK 1.6757 | MYL7 1.6682 | FGF20 1.6668 | ITGB5 1.6653 | MAPK3 1.6641 | CHRM2 1.6519 | ITGA6 1.6515 | IQGAP3 1.6459 | KRAS 1.6419 | PAK1 1.6191 | ARHGEF7 1.6022 | ITGA10 1.6014 | SOS2 1.5974 | ITGB4 1.5923 | BRAF 1.5539 | CD14 1.5535 | VCL 1.5498 | APC2 1.5322 | PIP5K1A 1.5040 | PDGFRA 1.4972 | PPP1CC 1.4919 | PIK3CA 1.4804 | CSK 1.4742 | PDGFRB 1.4665 | ITGA3 1.4609 | FGF11 1.4598 | DIAPH3 1.4523 | RRAS2 1.4290 | RAC3 1.4192 | CRK 1.4166 | PIP4K2A 1.4151 | GNG12 1.4145 | PIK3R2 1.4143 | MYH10 1.4107 | EZR 1.4086 | FGFR3 1.4082 | FGF10 1.4067 | FGF7 1.4049 | FGF17 1.3938 | PIK3CB 1.3849 | F2 1.3532 | PAK2 1.3442 | ITGAL 1.3308 | ARPC5L 1.3285 | WASF2 1.3228 | IQGAP1 1.3192 | MAP2K2 1.3141 | ITGB6 1.2993 | MOS 1.2953 | ACTN2 1.2903 | MYLK3 1.2840 | ROCK1 1.2802 | MYL9 1.2691 | ITGB7 1.2638 | DIAPH1 1.2479 | CHRM5 1.2440 | BDKRB2 1.2390 | FN1 1.2328 | WASF1 1.2328 | RAF1 1.2321 | ITGB3 1.2237 | ITGAM 1.2111 | ITGAX 1.2111 | PFN2 1.1950 | CFL2 1.1942 | PIK3R1 1.1894 | BDKRB1 1.1635 | PIK3CG 1.1284 | PFN1 1.1283 | PPP1R12A 1.1124 | ITGA7 1.1013 | GSN 1.0994 | CFL1 1.0981 | MYL10 1.0953 | MYL2 1.0664 | PAK4 1.0641 | ARPC4 1.0472 | MYLK2 1.0363 | CRKL 1.0292 | MYLPF 1.0237 | INS 1.0072 | MRAS 1.0046 | ACTN4 1.0023 | ITGAD 0.9996 | FGFR1 0.9682 | PXN 0.9662 | RRAS 0.9650 | FGF8 0.9108 | LIMK2 0.9101 | ITGA4 0.8908 | PPP1CA 0.8778 | PPP1CB 0.8684 | SSH3 0.8598 | PIK3R3 0.8554 | LIMK1 0.8533 | ITGA5 0.8523 | PIP4K2C 0.8422 | WASL 0.8245 | F2R 0.7926 | NRAS 0.7783 | PFN4 0.6540 | SOS1 0.6101 | ARPC1A 0.5839 | CHRM4 0.5343 | ARPC5 0.4487 | ARPC3 0.4176 | ARPC1B 0.3484 | Regulation of actin cytoskeleton | 646048 | 646821 | ARAF | ARHGEF6 | C3orf10 | DIAPH2 | FGD1 | FGF13 | FGF16 | GRLF1 | LOC653888 | MSN | PAK3 | TMSB4X | TMSB4Y | TMSL3 | WAS |
hsa05410 (boxplot) | 80 | 86 | 3.594447559594736 | 1.6254030526041685E-4 | 0.003104519830473962 | 0.0 | RYR2 4.0432 | SLC8A1 3.8778 | ACTB 3.7300 | TGFB2 3.6070 | CACNB2 3.4475 | CACNA1C 3.1697 | ITGA9 2.9512 | CACNA2D3 2.9129 | SGCG 2.8471 | DAG1 2.8456 | CACNA1S 2.7820 | ITGB1 2.7206 | CACNG2 2.7033 | SGCD 2.6291 | ITGA8 2.4888 | ACTG1 2.4632 | CACNB4 2.3591 | ITGA2B 2.3301 | ITGAV 2.3143 | CACNA2D4 2.2869 | PRKAG1 2.2812 | TTN 2.2689 | TNF 2.2219 | MYL3 2.1233 | CACNA1D 2.1133 | ITGA2 2.1044 | CACNG7 2.0613 | CACNG8 2.0613 | PRKAG2 2.0168 | TNNC1 2.0141 | TPM2 1.9662 | IGF1 1.9296 | PRKAB1 1.8791 | CACNG3 1.8755 | ITGA1 1.8523 | PRKAA2 1.8351 | ITGA11 1.8142 | TNNT2 1.7781 | ACTC1 1.7680 | CACNA2D1 1.7625 | SGCA 1.7333 | ITGB8 1.7109 | CACNB3 1.6975 | LAMA2 1.6851 | ITGB5 1.6653 | ITGA6 1.6515 | CACNG6 | ITGA10 1.6014 | ITGB4 1.5923 | TNNI3 1.5919 | CACNG4 1.4950 | TGFB1 1.4755 | ITGA3 1.4609 | PRKAB2 1.4585 | PRKAA1 1.4145 | DES 1.4059 | CACNG5 1.3384 | ITGB6 1.2993 | ACE 1.2989 | ITGB7 1.2638 | TPM4 1.2423 | ITGB3 1.2237 | CACNG1 1.2169 | MYH6 1.2039 | PRKAG3 1.1741 | ITGA7 1.1013 | CACNB1 1.0777 | MYL2 1.0664 | MYBPC3 1.0532 | MYH7 1.0003 | LMNA 0.9488 | TPM3 0.9322 | TPM1 0.9024 | CACNA2D2 0.8993 | ITGA4 0.8908 | ITGA5 0.8523 | IL6 0.8242 | TGFB3 0.8111 | ATP2A2 0.5605 | SGCB 0.5305 | DMD 0.3468 | Hypertrophic cardiomyopathy (HCM) | 646048 | 646821 | CACNA1F | EMD | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04540 (boxplot) | 84 | 91 | 3.5573507188539963 | 1.8730692992541265E-4 | 0.0032523294196139833 | 0.0 | ADCY9 4.0587 | MAP2K5 3.4532 | PLCB3 3.0689 | PRKG1 3.0481 | PLCB2 3.0466 | PRKCB 3.0263 | ADCY2 2.9743 | PRKG2 2.9686 | GUCY1A2 2.9322 | ITPR1 2.8897 | PRKCA 2.7739 | TUBA1B 2.7111 | ITPR2 2.6702 | TUBB8 2.6392 | PRKACG 2.6173 | TUBA1A 2.6017 | MAP2K1 2.5626 | ITPR3 2.5571 | PDGFC 2.4824 | CDK1 2.4729 | TUBA4A 2.4324 | TUBA3C 2.4040 | EGFR 2.3734 | GRM1 2.3621 | MAPK1 2.1844 | PLCB1 2.1804 | GUCY1A3 2.0975 | GUCY1B3 | PDGFA 2.0484 | PRKACB 2.0477 | GNAI3 2.0223 | GNA11 2.0156 | HTR2A 2.0155 | ADCY1 1.9897 | EGF 1.9813 | PDGFD 1.9570 | PRKCG 1.8526 | PDGFB 1.8438 | TUBB3 1.8422 | ADCY6 1.8202 | GNAS 1.7902 | MAP3K2 1.7881 | ADCY8 1.7592 | PLCB4 1.7585 | HRAS 1.7462 | ADCY5 1.6975 | GJD2 1.6741 | MAPK3 1.6641 | KRAS 1.6419 | SRC 1.6146 | GNAI1 1.6096 | SOS2 1.5974 | DRD1 1.5418 | TUBA8 1.5110 | GRM5 1.4972 | PDGFRA 1.4972 | PDGFRB 1.4665 | TUBB 1.3996 | GNAQ 1.3514 | DRD2 1.3506 | LPAR1 1.3435 | TUBB6 1.3255 | TUBA1C 1.3218 | MAP2K2 1.3141 | ADRB1 1.2389 | RAF1 1.2321 | TJP1 1.2232 | TUBAL3 1.1884 | PRKACA 1.1632 | GJA1 1.1360 | ADCY3 1.1011 | TUBB1 1.0718 | TUBB2A 1.0041 | TUBB2B 0.9931 | ADCY4 0.9872 | CSNK1D 0.9842 | TUBA3E 0.9776 | TUBA3D 0.8897 | GRB2 0.8222 | NRAS 0.7783 | SOS1 0.6101 | ADCY7 0.6048 | HTR2B 0.5571 | GNAI2 0.3699 | MAPK7 0.2593 | Gap junction | HTR2C | PRKX | TUBB2C | TUBB4 | TUBB4Q | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04070 (boxplot) | 77 | 79 | 3.4795657055041596 | 2.51113599225139E-4 | 0.003996891454333462 | 0.0 | CDS2 3.4943 | PIK3R5 3.1433 | PLCB3 3.0689 | PLCB2 3.0466 | PRKCB 3.0263 | ITPR1 2.8897 | PLCG2 2.8847 | PRKCA 2.7739 | DGKD 2.7464 | SYNJ2 2.7140 | INPP5K 2.7011 | INPP5B 2.6895 | ITPR2 2.6702 | PIP5K1B 2.6173 | ITPR3 2.5571 | PLCG1 2.5010 | CDIPT 2.4835 | PIP5K1C 2.4349 | INPP5D 2.3183 | INPP4B 2.2677 | ITPK1 2.2343 | PLCB1 2.1804 | PIK3C2G 2.1696 | PIK3C2A 2.1242 | PIKFYVE 2.1044 | CALM1 2.0863 | PIK3C2B 2.0793 | DGKH 2.0785 | DGKB 2.0648 | DGKI 2.0180 | DGKG 1.9910 | PI4K2A 1.9289 | IMPA2 1.9073 | PLCZ1 1.9038 | DGKE 1.9024 | INPP5A 1.8768 | PRKCG 1.8526 | IMPA1 1.8225 | DGKQ 1.7905 | PI4KA 1.7902 | PLCB4 1.7585 | PLCD4 1.7471 | PIP4K2B 1.7345 | PIK3CD 1.7138 | PLCE1 1.6609 | INPPL1 1.5674 | CALML5 1.5580 | CALM2 1.5462 | PI4KB 1.5160 | PIP5K1A 1.5040 | PIK3CA 1.4804 | ITPKB 1.4598 | CDS1 1.4319 | PIP4K2A 1.4151 | PIK3R2 1.4143 | PLCD3 1.4143 | PIK3CB 1.3849 | PIK3C3 1.3596 | PLCD1 1.2517 | PI4K2B 1.2178 | PIK3R1 1.1894 | CALML3 1.1643 | ITPKA 1.1510 | PIK3CG 1.1284 | DGKZ 1.0924 | INPP4A 1.0267 | CALM3 0.9846 | PTEN 0.8976 | DGKA 0.8887 | IPPK 0.8713 | INPP5J 0.8557 | PIK3R3 0.8554 | SYNJ1 0.8533 | INPP1 0.8422 | PIP4K2C 0.8422 | INPP5E 0.8268 | CALML6 0.5979 | Phosphatidylinositol signaling system | OCRL | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05416 (boxplot) | 67 | 76 | 3.3748825457957636 | 3.6923600555027747E-4 | 0.005424929004623307 | 0.0 | HLA-DQA1 4.6600 | HLA-DQB1 4.6600 | ACTB 3.7300 | HLA-DRB1 3.2362 | SGCG 2.8471 | DAG1 2.8456 | RAC2 2.8280 | HLA-DRB5 2.7440 | MYH9 2.7326 | MYH13 2.7310 | HLA-DOB 2.6796 | RAC1 2.6726 | CXADR 2.6724 | HLA-B 2.6605 | MYH3 2.6392 | SGCD 2.6291 | MYH11 2.6183 | ACTG1 2.4632 | ITGB2 2.3293 | MYH14 2.2453 | FYN 2.2385 | MYH8 2.1503 | HLA-DOA 2.1076 | CD80 2.0016 | HLA-DRA 1.9559 | CD40 1.9289 | MYH15 1.9278 | CAV1 1.8147 | BID 1.7983 | SGCA 1.7333 | LAMA2 1.6851 | HLA-A 1.6214 | HLA-F 1.6214 | CYCS 1.5581 | HLA-C 1.5498 | HLA-DPA1 1.5330 | MYH4 1.5321 | HLA-G 1.5274 | ABL1 1.5088 | CASP8 1.4823 | RAC3 1.4192 | MYH10 1.4107 | CCND1 1.4000 | HLA-DPB1 1.3901 | HLA-E 1.3786 | HLA-DMA 1.3629 | HLA-DMB | EIF4G2 1.3427 | ITGAL 1.3308 | CASP3 1.3249 | HLA-DQA2 1.2857 | EIF4G3 1.2812 | EIF4G1 1.2172 | MYH6 1.2039 | CD55 1.1180 | MYH2 1.0753 | PRF1 1.0635 | MYH1 1.0547 | CASP9 1.0188 | MYH7 1.0003 | ICAM1 0.9880 | ABL2 0.9821 | CD28 0.8959 | CD86 0.8362 | MYH7B 0.8142 | HLA-DRB3 0.5719 | SGCB 0.5305 | DMD 0.3468 | Viral myocarditis | 100294318 | 646048 | 646821 | CD40LG | HLA-DRB4 | LOC100133583 | LOC652614 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05110 (boxplot) | 52 | 57 | 3.3481898546385063 | 4.067063374464386E-4 | 0.005548636460876412 | 0.0 | ATP6V1D 6.8083 | ADCY9 4.0587 | ACTB 3.7300 | ATP6V0A4 3.7210 | ATP6V1B2 3.1036 | PRKCB 3.0263 | PLCG2 2.8847 | PRKCA 2.7739 | PRKACG 2.6173 | PLCG1 2.5010 | ACTG1 2.4632 | KDELR3 2.2920 | ATP6V1G2 2.2008 | TJP2 2.1614 | KCNQ1 2.1246 | ATP6V1F 2.1069 | ATP6V0D1 2.0982 | ATP6V0D2 2.0833 | SEC61B 2.0569 | PRKACB 2.0477 | ATP6V1C2 2.0315 | ERO1L 2.0097 | PRKCG 1.8526 | ATP6V1B1 1.8256 | GNAS 1.7902 | ATP6V0E2 1.7471 | SLC12A2 1.6803 | PDIA4 1.5281 | ATP6V1A 1.5081 | MUC2 1.4464 | ATP6V1E1 1.4383 | TCIRG1 1.3255 | SEC61A2 1.2317 | KDELR2 1.2303 | TJP1 1.2232 | ATP6V1H 1.2160 | ARF1 1.2083 | ATP6V1C1 1.1984 | ATP6V0B 1.1900 | PRKACA 1.1632 | ATP6V0E1 1.1421 | ADCY3 1.1011 | CFTR 1.0896 | ATP6V1G3 1.0115 | ATP6V0A1 0.9809 | ATP6V1G1 0.9622 | ATP6V0A2 0.9314 | ATP6V0C 0.9052 | SEC61G 0.8798 | SEC61A1 0.8523 | ATP6V1E2 0.6568 | KDELR1 0.5490 | Vibrio cholerae infection | 646048 | 646821 | ATP6AP1 | PRKX | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa00230 (boxplot) | 152 | 162 | 3.3189267611185613 | 4.518206318037121E-4 | 0.005753182711633934 | 0.0 | FHIT 5.0721 | GDA 4.0631 | ADCY9 4.0587 | ADSSL1 3.8453 | AMPD3 3.8074 | PAPSS1 3.6811 | POLR3D 3.5763 | PDE6D 3.4731 | PDE10A 3.3367 | PDE3B 3.1873 | PAICS 3.1341 | ZNRD1 3.0116 | RRM2B 3.0016 | ADCY2 2.9743 | AK4 2.9446 | GUCY1A2 2.9322 | PDE11A 2.9080 | POLR2L 2.8996 | POLR3C 2.7118 | IMPDH1 2.7009 | ATIC 2.6091 | POLR2G 2.6091 | PDE4D 2.5473 | PDE4B 2.5046 | ENTPD1 2.3727 | ADK 2.3639 | PNPT1 2.3428 | PPAT 2.3246 | NUDT5 2.3176 | ENTPD4 2.3160 | GART 2.3004 | PDE1A 2.2989 | POLR2J 2.2852 | CANT1 2.2812 | NT5C2 2.2201 | PDE8B 2.2053 | PDE3A 2.1902 | PDE2A 2.1852 | ITPA 2.1519 | NT5C1A 2.1493 | POLR2E 2.1467 | PDE7B 2.1433 | C17orf48 2.1354 | GUCY2C 2.1308 | POLR2K 2.1174 | GUCY1A3 2.0975 | GUCY1B3 | POLD2 2.0875 | PRIM1 2.0426 | POLR3F 2.0054 | ADCY1 1.9897 | PDE6C 1.9884 | POLR2I 1.9722 | PGM2 1.9602 | PDE6A 1.9578 | GUCY2D 1.9512 | PDE6B 1.9355 | POLR2B 1.9112 | POLE3 1.8841 | PDE7A 1.8545 | ENPP1 1.8386 | ADCY6 1.8202 | PDE1C 1.8136 | PDE9A 1.8052 | XDH 1.8000 | NME5 1.7881 | POLR3A 1.7703 | POLR3B 1.7630 | ADCY8 1.7592 | NPR2 1.7582 | PDE8A 1.7411 | POLR3G 1.7359 | POLE2 1.7326 | AK7 1.7005 | ADCY5 1.6975 | NT5E 1.6726 | AMPD2 1.6692 | RRM1 1.6666 | PNP 1.6149 | ENTPD8 1.5996 | NUDT9 1.5901 | POLD1 1.5784 | POLR3H 1.5771 | POLR2A 1.5733 | NT5C 1.5680 | PGM1 1.5240 | PDE5A 1.4692 | NPR1 1.4554 | ENPP3 1.4479 | NUDT2 1.4406 | POLR2C 1.4209 | POLR2D 1.4144 | ENTPD3 1.3840 | PRUNE 1.3618 | ALLC 1.3577 | GMPS 1.3548 | PRHOXNB 1.3496 | POLR3GL 1.3168 | ENTPD5 1.2977 | NT5M 1.2974 | NME4 1.2821 | DGUOK 1.2597 | AK5 1.1955 | NT5C1B 1.1929 | PDE6H 1.1860 | POLE4 1.1812 | ADSL 1.1654 | APRT 1.1540 | POLR2H 1.1419 | ADA 1.1337 | IMPDH2 1.1259 | POLR3K 1.1138 | POLR1A 1.1062 | ADCY3 1.1011 | PDE6G 1.0988 | PFAS 1.0971 | POLR1D 1.0958 | ADCY10 1.0887 | ADSS 1.0754 | PDE1B 1.0754 | PRPS1L1 1.0541 | PAPSS2 1.0474 | AK1 1.0307 | GUK1 1.0281 | POLD3 1.0132 | ADCY4 0.9872 | POLE 0.9543 | POLR1E 0.9512 | GMPR 0.9500 | RRM2 0.9462 | PDE4C 0.9393 | NME7 0.9158 | POLD4 0.9133 | NME3 0.9052 | PDE4A 0.8732 | GMPR2 0.8401 | PRIM2 0.8336 | NT5C3 0.8193 | ENTPD6 0.8002 | AMPD1 0.7783 | NME1 0.7605 | NME1-NME2 | NME2 | POLA2 0.7520 | PKM2 0.7385 | NME6 0.7312 | POLR2J3 0.7183 | POLR1B 0.6908 | POLR1C 0.6080 | ADCY7 0.6048 | PKLR 0.5988 | ENTPD2 0.5810 | POLR2F 0.4866 | DCK 0.4667 | POLR2J2 | AK2 0.2264 | Purine metabolism | GUCY2F | HPRT1 | POLA1 | PRPS1 | PRPS2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05218 (boxplot) | 68 | 72 | 3.2612845785822495 | 5.545433482148088E-4 | 0.00661986121931428 | 0.0 | FGF19 3.3729 | FGF14 3.3354 | PIK3R5 3.1433 | FGF23 3.0977 | BAD 3.0689 | E2F2 2.9408 | FGF3 2.8496 | CDK4 2.7978 | IGF1R 2.5914 | MAP2K1 2.5626 | PDGFC 2.4824 | EGFR 2.3734 | FGF4 2.3650 | TP53 2.3206 | FGF2 2.2467 | FGF12 2.2433 | MAPK1 2.1844 | FGF18 2.1111 | FGF6 2.1109 | RB1 2.1039 | E2F1 2.0545 | PDGFA 2.0484 | FGF5 2.0384 | FGF9 2.0338 | HGF 2.0308 | EGF 1.9813 | PDGFD 1.9570 | IGF1 1.9296 | CDKN2A 1.8817 | E2F3 1.8742 | PDGFB 1.8438 | FGF21 1.8435 | FGF1 1.7572 | FGF22 1.7491 | HRAS 1.7462 | PIK3CD 1.7138 | AKT1 1.7014 | FGF20 1.6668 | MAPK3 1.6641 | KRAS 1.6419 | BRAF 1.5539 | CDH1 1.5358 | MDM2 1.5358 | PDGFRA 1.4972 | PIK3CA 1.4804 | PDGFRB 1.4665 | FGF11 1.4598 | PIK3R2 1.4143 | FGF10 1.4067 | FGF7 1.4049 | CCND1 1.4000 | FGF17 1.3938 | MET 1.3873 | PIK3CB 1.3849 | MAP2K2 1.3141 | MITF 1.3118 | CDKN1A 1.2652 | RAF1 1.2321 | PIK3R1 1.1894 | PIK3CG 1.1284 | CDK6 1.0654 | AKT3 0.9935 | FGFR1 0.9682 | FGF8 0.9108 | AKT2 0.9017 | PTEN 0.8976 | PIK3R3 0.8554 | NRAS 0.7783 | Melanoma | ARAF | FGF13 | FGF16 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04920 (boxplot) | 64 | 68 | 3.2220301808519616 | 6.364286327202873E-4 | 0.007150462873504403 | 0.0 | PCK1 3.6017 | MTOR 3.5430 | TRADD 3.1408 | CHUK 2.7392 | LEPR 2.7333 | MAPK8 2.6033 | MAPK10 2.5394 | RXRG 2.4598 | ADIPOR1 2.4224 | NPY 2.3003 | JAK2 2.2993 | PRKAG1 2.2812 | NFKBIA 2.2646 | PCK2 2.2621 | RXRA 2.2312 | TNF 2.2219 | ACSL5 2.2201 | ACACB 2.1717 | PPARA 2.1378 | POMC 2.1150 | RXRB 2.1076 | AGRP 2.0982 | IKBKB 2.0647 | PPARGC1A 2.0619 | CAMKK2 2.0282 | PRKAG2 2.0168 | PRKCQ 1.9582 | PTPN11 1.9382 | NFKBIE 1.9165 | PRKAB1 1.8791 | G6PC 1.8551 | CPT1B 1.8505 | PRKAA2 1.8351 | STAT3 1.8289 | CPT1C 1.7902 | CAMKK1 1.7875 | CPT1A 1.7192 | AKT1 1.7014 | TRAF2 1.6469 | STK11 1.5387 | ACSL1 1.5224 | LEP 1.5148 | IRS2 1.4841 | PRKAB2 1.4585 | SOCS3 1.4412 | PRKAA1 1.4145 | ADIPOR2 1.4043 | MAPK9 1.4013 | ADIPOQ 1.3722 | SLC2A4 1.3574 | TNFRSF1B 1.3515 | NFKB1 1.1903 | RELA 1.1750 | PRKAG3 1.1741 | SLC2A1 1.1598 | NFKBIB 1.1025 | IRS1 1.1009 | TNFRSF1A 1.0996 | ACSL6 1.0971 | G6PC2 1.0466 | AKT3 0.9935 | CD36 0.9735 | ACSL3 0.9389 | AKT2 0.9017 | Adipocytokine signaling pathway | ACSL4 | IKBKG | IRS4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05322 (boxplot) | 96 | 143 | 3.2078479781081093 | 6.686608404289363E-4 | 0.007150462873504403 | 0.0 | HLA-DQA1 4.6600 | HLA-DQB1 4.6600 | HIST1H4C 3.3830 | HLA-DRB1 3.2362 | ACTN1 3.0707 | HIST1H3A 2.9296 | HIST1H4A | HIST1H2AC 2.8732 | HIST1H2BC | HLA-DRB5 2.7440 | HIST1H2AB 2.7282 | HIST1H2BB 2.7282 | HIST1H3B | HIST1H4B | HLA-DOB 2.6796 | HIST1H3C 2.6710 | C8B 2.6531 | TROVE2 2.5728 | H2AFY2 2.5696 | C6 2.5071 | FCGR2B 2.4253 | HIST1H2BD 2.3935 | HIST1H2AM 2.3502 | HIST1H2BO | HIST1H3J | GRIN2B 2.2739 | C1S 2.2380 | GRIN2A 2.2237 | TNF 2.2219 | ACTN3 2.2041 | HLA-DOA 2.1076 | HIST1H2BE 2.0265 | HIST1H3D 2.0265 | HIST1H4D | C4A 2.0033 | C4B | CD80 2.0016 | HIST1H2AL 1.9662 | HIST1H3I 1.9662 | HIST1H4L | HIST1H2AI 1.9638 | HIST1H2AJ 1.9638 | HIST1H2AK 1.9638 | HIST1H2BL | HIST1H2BM | HIST1H2BN | HIST1H3H | HIST1H4J | HIST1H4K | HIST1H2AG 1.9578 | HIST1H2BJ 1.9578 | HIST1H2BK 1.9578 | HIST1H4I 1.9578 | HLA-DRA 1.9559 | HIST1H2AD 1.9374 | HIST1H2BF | HIST1H2BG 1.9374 | HIST1H4E 1.9374 | CD40 1.9289 | HIST1H2AH | H2AFY 1.8925 | SNRPD3 1.8542 | C7 1.8419 | TRIM21 1.8383 | HIST1H4H 1.8105 | HIST2H2AB 1.7380 | HIST2H2AC | HIST2H2BE | C3 1.7226 | ELANE 1.6430 | FCGR2C 1.6169 | FCGR3B 1.6169 | IFNG 1.6146 | FCGR1A 1.5989 | HIST2H2BF | C1R 1.5672 | H2AFV 1.5634 | HLA-DPA1 1.5330 | FCGR3A 1.5067 | SNRPB 1.5024 | C9 1.4271 | SSB 1.3920 | HLA-DPB1 1.3901 | H2AFJ 1.3654 | HIST4H4 | HLA-DMA 1.3629 | HLA-DMB | HIST1H2BH 1.3140 | HIST1H2BI | HIST1H3F | HIST1H3G | HIST1H4F 1.3140 | HIST1H4G 1.3140 | C8A 1.3135 | CTSG 1.2958 | ACTN2 1.2903 | HLA-DQA2 1.2857 | HIST3H3 1.2829 | HIST1H2AE 1.2750 | C2 1.2667 | HIST1H3E 1.2396 | H3F3C 1.2274 | H3F3B 1.2205 | HIST1H2AA 1.2036 | HIST1H2BA | H3F3A 1.1067 | FCGR2A 1.0661 | SNRPD1 1.0048 | ACTN4 1.0023 | C5 0.9935 | IL10 0.9674 | CD28 0.8959 | CD86 0.8362 | C1QA 0.8345 | C8G 0.8170 | C1QB 0.7488 | C1QC | H2AFZ 0.7300 | H2AFX 0.6733 | HLA-DRB3 0.5719 | HIST2H2AA3 0.5694 | HIST2H2AA4 | HIST2H3A | HIST2H3C | HIST2H4A | HIST2H4B | HIST3H2A 0.4878 | HIST3H2BB | HIST2H3D 0.2870 | Systemic lupus erythematosus | 100294318 | CD40LG | H2AFB1 | H2AFB2 | H2AFB3 | H2BFM | H2BFWT | HLA-DRB4 | LOC100133583 | LOC340096 | LOC391769 | LOC644950 | LOC651868 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04020 (boxplot) | 167 | 179 | 3.2039077565836798 | 6.778795331796594E-4 | 0.007150462873504403 | 0.0 | ADCY9 4.0587 | RYR2 4.0432 | GNAL 3.9763 | SLC8A1 3.8778 | CAMK2A 3.5158 | HTR7 3.3218 | CACNA1C 3.1697 | PLCB3 3.0689 | PLCB2 3.0466 | PRKCB 3.0263 | ADCY2 2.9743 | CACNA1A 2.9234 | ITPR1 2.8897 | PLCG2 2.8847 | LHCGR 2.8000 | CACNA1S 2.7820 | PRKCA 2.7739 | CHRM3 2.7411 | ATP2B2 2.7192 | ITPR2 2.6702 | PTK2B 2.6525 | NOS1 2.6267 | PRKACG 2.6173 | CACNA1E 2.6002 | CAMK2D 2.5763 | ITPR3 2.5571 | PLCG1 2.5010 | CACNA1B 2.4467 | RYR3 2.4145 | GRIN2D 2.4098 | CAMK4 2.3903 | EGFR 2.3734 | GRM1 2.3621 | ATP2A3 2.3245 | PDE1A 2.2989 | ATP2B4 2.2917 | HTR4 2.2451 | GRIN2A 2.2237 | TACR1 2.1975 | PLCB1 2.1804 | CACNA1D 2.1133 | BST1 2.0934 | CALM1 2.0863 | CACNA1G 2.0559 | PRKACB 2.0477 | P2RX4 2.0282 | TACR2 2.0266 | GNA11 2.0156 | HTR2A 2.0155 | NOS3 2.0146 | TNNC1 2.0141 | ADRA1D 2.0075 | VDAC2 1.9935 | ADCY1 1.9897 | CAMK2G 1.9776 | NOS2 1.9614 | GNA15 1.9606 | ADRA1B 1.9263 | NTSR1 1.9248 | SPHK1 1.9245 | P2RX6 1.9212 | PPP3CA 1.9062 | PLCZ1 1.9038 | CACNA1H 1.8962 | SLC8A3 1.8901 | PRKCG 1.8526 | CYSLTR2 1.8395 | ERBB4 1.8386 | PTGFR 1.8150 | PDE1C 1.8136 | GNAS 1.7902 | CHRM1 1.7817 | GNA14 1.7701 | AVPR1B 1.7622 | ADCY8 1.7592 | PLCB4 1.7585 | PLCD4 1.7471 | P2RX5 1.7335 | ADRA1A 1.7235 | MYLK 1.6757 | PLCE1 1.6609 | CHP2 1.6574 | CHRM2 1.6519 | PPP3R2 1.6507 | PPP3R1 1.6073 | HRH1 1.6028 | TRHR 1.5743 | CALML5 1.5580 | CALM2 1.5462 | DRD1 1.5418 | EDNRB 1.5346 | GRM5 1.4972 | PDGFRA 1.4972 | P2RX7 1.4953 | SLC8A2 1.4703 | PDGFRB 1.4665 | ITPKB 1.4598 | PHKB 1.4395 | AVPR1A 1.4388 | RYR1 1.4385 | PLCD3 1.4143 | OXTR 1.4085 | ADRB2 1.4067 | P2RX2 1.3935 | PTGER1 1.3931 | HTR6 1.3827 | VDAC3 1.3817 | PPID 1.3726 | HRH2 1.3590 | GNAQ 1.3514 | P2RX1 1.3213 | ERBB3 1.3159 | MYLK3 1.2840 | PPP3CC 1.2662 | CACNA1I 1.2623 | PTGER3 1.2596 | PLCD1 1.2517 | ADORA2B 1.2450 | CHRM5 1.2440 | BDKRB2 1.2390 | ADRB1 1.2389 | TNNC2 1.2210 | AGTR1 1.1970 | P2RX3 1.1948 | TACR3 1.1917 | LTB4R2 1.1771 | CALML3 1.1643 | BDKRB1 1.1635 | PRKACA 1.1632 | ITPKA 1.1510 | EDNRA 1.1459 | SLC25A31 1.1290 | GRIN2C 1.1180 | CHRNA7 1.1090 | ADCY3 1.1011 | ATP2B1 1.0767 | PDE1B 1.0754 | CCKAR 1.0564 | HTR5A 1.0440 | MYLK2 1.0363 | TRPC1 1.0146 | ADCY4 0.9872 | ATP2A1 0.9851 | CALM3 0.9846 | CD38 0.9739 | TBXA2R 0.9727 | ERBB2 0.9686 | DRD5 0.9670 | PLN 0.9027 | SPHK2 0.9024 | SLC25A4 0.8979 | CAMK2B 0.8788 | PTAFR 0.8407 | GRIN1 0.8321 | ADORA2A 0.8219 | F2R 0.7926 | CCKBR 0.7807 | PHKG1 0.7476 | VDAC1 0.6794 | ADCY7 0.6048 | CALML6 0.5979 | PHKG2 0.5952 | ATP2A2 0.5605 | HTR2B 0.5571 | ADRB3 0.4798 | PPP3CB 0.4679 | CYSLTR1 0.0433 | Calcium signaling pathway | ATP2B3 | CACNA1F | CHP | GRPR | HTR2C | LOC729317 | PHKA1 | PHKA2 | PRKX | SLC25A5 | SLC25A6 | ||||||||||||||||||||||||||||||||||||||
hsa05222 (boxplot) | 81 | 85 | 3.1280660391151835 | 8.798032029586622E-4 | 0.008402120588255225 | 0.0 | FHIT 5.0721 | COL4A2 3.5427 | LAMC3 3.2308 | PIK3R5 3.1433 | E2F2 2.9408 | COL4A1 2.9190 | BCL2 2.8962 | CDK4 2.7978 | PTK2 2.7491 | CHUK 2.7392 | ITGB1 2.7206 | PIAS3 2.7118 | PTGS2 2.5139 | RXRG 2.4598 | LAMC1 2.3490 | ITGA2B 2.3301 | TP53 2.3206 | ITGAV 2.3143 | CCNE1 2.2847 | NFKBIA 2.2646 | TRAF6 2.2343 | RXRA 2.2312 | LAMA3 2.2199 | LAMA1 2.1908 | TRAF3 2.1366 | RXRB 2.1076 | ITGA2 2.1044 | RB1 2.1039 | IKBKB 2.0647 | E2F1 2.0545 | NOS2 1.9614 | LAMB4 1.9602 | RARB 1.9500 | COL4A4 1.8841 | E2F3 1.8742 | LAMA5 1.8536 | BIRC2 1.8533 | SKP2 1.7399 | PIK3CD 1.7138 | CDKN1B 1.7075 | AKT1 1.7014 | LAMA2 1.6851 | ITGA6 1.6515 | TRAF2 1.6469 | TRAF5 1.6297 | LAMC2 1.6114 | APAF1 1.5879 | CYCS 1.5581 | BIRC3 1.5424 | MAX 1.4862 | PIK3CA 1.4804 | LAMB3 1.4777 | ITGA3 1.4609 | PIK3R2 1.4143 | CCND1 1.4000 | PIK3CB 1.3849 | LAMA4 1.2720 | LAMB1 1.2559 | FN1 1.2328 | PIAS4 1.1979 | NFKB1 1.1903 | PIK3R1 1.1894 | RELA 1.1750 | TRAF1 1.1415 | PIK3CG 1.1284 | PIAS2 1.1259 | CDKN2B 1.0880 | CDK6 1.0654 | MYC 1.0337 | CASP9 1.0188 | AKT3 0.9935 | LAMB2 0.9751 | AKT2 0.9017 | PTEN 0.8976 | CDK2 0.8887 | PIK3R3 0.8554 | BCL2L1 0.7934 | CCNE2 0.6847 | CKS1B 0.6411 | TRAF4 0.5827 | PIAS1 0.4175 | Small cell lung cancer | COL4A6 | IKBKG | XIAP | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04520 (boxplot) | 72 | 76 | 3.1111122145351007 | 9.319204850966045E-4 | 0.008476038697783402 | 0.0 | BAIAP2 3.8173 | ACTB 3.7300 | CTNNA2 3.2208 | PTPN1 3.1283 | ACTN1 3.0707 | RAC2 2.8280 | INSR 2.7897 | RAC1 2.6726 | PTPRM 2.6623 | PVRL3 2.6476 | NLK 2.6407 | FARP2 2.6167 | TCF7L2 2.5921 | IGF1R 2.5914 | RHOA 2.5129 | PTPRF 2.4880 | ACTG1 2.4632 | EGFR 2.3734 | LMO7 2.2950 | SORBS1 2.2816 | FYN 2.2385 | ACTN3 2.2041 | MAPK1 2.1844 | CTNNA3 2.1832 | SMAD3 2.1398 | PVRL1 2.0014 | TCF7L1 1.9555 | MAP3K7 1.9122 | TGFBR2 1.8771 | CDC42 1.8213 | SMAD2 1.7778 | WASF3 1.7632 | CSNK2A1 1.6824 | MAPK3 1.6641 | SRC 1.6146 | PTPN6 1.5953 | PARD3 1.5924 | MLLT4 1.5911 | FER 1.5533 | VCL 1.5498 | EP300 1.5435 | CDH1 1.5358 | PVRL2 1.5039 | YES1 1.4362 | SNAI1 1.4351 | PTPRJ 1.4277 | RAC3 1.4192 | MET 1.3873 | SSX2IP 1.3359 | WASF2 1.3228 | IQGAP1 1.3192 | CREBBP 1.3089 | ACTN2 1.2903 | CSNK2B 1.2467 | PTPRB 1.2457 | WASF1 1.2328 | TJP1 1.2232 | CTNND1 1.2139 | SNAI2 1.1409 | TCF7 1.1162 | SMAD4 1.1109 | TGFBR1 1.0526 | CSNK2A2 1.0512 | ACTN4 1.0023 | CTNNA1 0.9825 | ERBB2 0.9686 | FGFR1 0.9682 | PVRL4 0.9630 | CTNNB1 0.9144 | LEF1 0.8952 | WASL 0.8245 | ACP1 0.7347 | Adherens junction | 646048 | 646821 | WAS | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04270 (boxplot) | 109 | 117 | 3.0126455171013853 | 0.0012949061916869287 | 0.011242140118736517 | 0.0 | ADCY9 4.0587 | PRKCD 3.3826 | CACNA1C 3.1697 | PLCB3 3.0689 | PRKG1 3.0481 | PLCB2 3.0466 | PRKCB 3.0263 | ADCY2 2.9743 | GUCY1A2 2.9322 | ITPR1 2.8897 | CACNA1S 2.7820 | PRKCA 2.7739 | ITPR2 2.6702 | GNA12 2.6234 | MYH11 2.6183 | PRKACG 2.6173 | MAP2K1 2.5626 | ITPR3 2.5571 | KCNMB2 2.5154 | RHOA 2.5129 | PLA2G2A 2.4585 | PRKCE 2.4343 | PLA2G4A 2.4025 | RAMP3 2.2430 | KCNMB4 2.2259 | MAPK1 2.1844 | PLCB1 2.1804 | CACNA1D 2.1133 | GUCY1A3 2.0975 | GUCY1B3 | PLA2G5 2.0932 | CALM1 2.0863 | ROCK2 2.0579 | PRKACB 2.0477 | GNA13 2.0279 | GNA11 2.0156 | ARHGEF1 2.0091 | ADRA1D 2.0075 | ADCY1 1.9897 | PRKCQ 1.9582 | ADRA1B 1.9263 | CALD1 1.8700 | PRKCG 1.8526 | ADCY6 1.8202 | GNAS 1.7902 | KCNMA1 1.7742 | CYP4A11 1.7739 | AVPR1B 1.7622 | ADCY8 1.7592 | PLCB4 1.7585 | NPR2 1.7582 | KCNMB3 1.7525 | ARHGEF12 1.7452 | ADRA1A 1.7235 | ADCY5 1.6975 | CYP4A22 1.6914 | MYLK 1.6757 | MAPK3 1.6641 | MRVI1 1.6631 | CALML5 1.5580 | PLA2G10 1.5567 | BRAF 1.5539 | RAMP1 1.5471 | CALM2 1.5462 | KCNU1 1.5040 | PPP1R14A 1.5005 | JMJD7-PLA2G4B 1.4984 | PLA2G4B | PPP1CC 1.4919 | PRKCH 1.4763 | NPR1 1.4554 | AVPR1A 1.4388 | GNAQ 1.3514 | PLA2G6 1.3336 | PLA2G2D 1.3238 | KCNMB1 1.3228 | PLA2G4E 1.3187 | MAP2K2 1.3141 | ACTA2 1.3076 | MYLK3 1.2840 | ROCK1 1.2802 | PTGIR 1.2763 | MYL9 1.2691 | ADORA2B 1.2450 | PLA2G12B 1.2433 | RAF1 1.2321 | AGTR1 1.1970 | PLA2G2C 1.1830 | PLA2G2F | CALML3 1.1643 | PRKACA 1.1632 | EDNRA 1.1459 | PPP1R12A 1.1124 | ADCY3 1.1011 | MYLK2 1.0363 | CALCRL 0.9940 | ADCY4 0.9872 | CALM3 0.9846 | PLA2G12A 0.9805 | RAMP2 0.9551 | PPP1R12B 0.8972 | PLA2G2E 0.8914 | MYL6 0.8801 | MYL6B | PPP1CA 0.8778 | PPP1CB 0.8684 | PLA2G3 0.8557 | ACTG2 0.8520 | ADORA2A 0.8219 | PLA2G1B 0.7612 | ADCY7 0.6048 | CALML6 0.5979 | ARHGEF11 0.5427 | Vascular smooth muscle contraction | ARAF | CACNA1F | PRKX | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04145 (boxplot) | 141 | 160 | 2.885667846343923 | 0.0019529206513002606 | 0.016217732365145645 | 0.0 | ATP6V1D 6.8083 | HLA-DQA1 4.6600 | HLA-DQB1 4.6600 | ACTB 3.7300 | ATP6V0A4 3.7210 | HLA-DRB1 3.2362 | EEA1 3.1377 | ATP6V1B2 3.1036 | TLR2 3.1008 | STX18 3.0429 | HLA-DRB5 2.7440 | ITGB1 2.7206 | TUBA1B 2.7111 | HLA-DOB 2.6796 | TAP1 | TAP2 | RAC1 2.6726 | HLA-B 2.6605 | TUBB8 2.6392 | NOS1 2.6267 | TUBA1A 2.6017 | COLEC12 2.5875 | OLR1 2.5375 | ACTG1 2.4632 | TUBA4A 2.4324 | FCGR2B 2.4253 | SFTPA1 2.4115 | TUBA3C 2.4040 | COMP 2.3919 | STX7 2.3484 | COLEC11 2.3413 | ITGB2 2.3293 | ITGAV 2.3143 | ATP6V1G2 2.2008 | DYNC2H1 2.1583 | NOX3 2.1286 | HLA-DOA 2.1076 | ATP6V1F 2.1069 | ITGA2 2.1044 | PIKFYVE 2.1044 | ATP6V0D1 2.0982 | ATP6V0D2 2.0833 | SEC61B 2.0569 | RAB7A 2.0354 | ATP6V1C2 2.0315 | CLEC7A 2.0233 | HLA-DRA 1.9559 | MARCO 1.9367 | DYNC1I2 1.9108 | SCARB1 1.8972 | PLA2R1 1.8824 | CLEC4M 1.8761 | MSR1 1.8620 | TUBB3 1.8422 | ATP6V1B1 1.8256 | NCF4 1.7726 | ATP6V0E2 1.7471 | C3 1.7226 | CD209 1.6851 | CALR 1.6755 | ITGB5 1.6653 | TLR4 1.6570 | HLA-A 1.6214 | HLA-F 1.6214 | FCGR2C 1.6169 | FCGR3B 1.6169 | DYNC1I1 1.6139 | FCGR1A 1.5989 | SFTPD 1.5802 | C1R 1.5672 | CD14 1.5535 | HLA-C 1.5498 | MBL2 1.5441 | HLA-DPA1 1.5330 | HLA-G 1.5274 | TUBA8 1.5110 | ATP6V1A 1.5081 | FCGR3A 1.5067 | MRC2 1.4861 | VAMP3 1.4837 | ATP6V1E1 1.4383 | TLR6 1.4305 | DYNC1LI1 1.4124 | CANX 1.4001 | TUBB 1.3996 | HLA-DPB1 1.3901 | HLA-E 1.3786 | HLA-DMA 1.3629 | HLA-DMB | PIK3C3 1.3596 | DYNC1H1 1.3386 | TCIRG1 1.3255 | TUBB6 1.3255 | TUBA1C 1.3218 | MPO 1.2914 | HLA-DQA2 1.2857 | TFRC 1.2478 | SEC61A2 1.2317 | ITGB3 1.2237 | ATP6V1H 1.2160 | THBS4 1.2117 | CTSL1 1.2115 | ITGAM 1.2111 | FCAR 1.2076 | ATP6V1C1 1.1984 | CYBA 1.1917 | ATP6V0B 1.1900 | TUBAL3 1.1884 | NCF2 1.1882 | CTSS 1.1841 | ATP6V0E1 1.1421 | NCF1 1.1245 | RAB5A 1.1142 | THBS2 1.0954 | TUBB1 1.0718 | M6PR 1.0695 | FCGR2A 1.0661 | ATP6V1G3 1.0115 | TUBB2A 1.0041 | TUBB2B 0.9931 | ATP6V0A1 0.9809 | TUBA3E 0.9776 | CD36 0.9735 | ATP6V1G1 0.9622 | RILP 0.9337 | ATP6V0A2 0.9314 | ATP6V0C 0.9052 | TUBA3D 0.8897 | RAB5B 0.8887 | SEC61G 0.8798 | ITGA5 0.8523 | SEC61A1 0.8523 | RAB5C 0.7943 | SEC22B 0.7533 | DYNC1LI2 0.7387 | MRC1 0.7357 | CORO1A 0.7003 | THBS3 0.6651 | ATP6V1E2 0.6568 | HGS 0.6249 | LAMP1 0.6180 | HLA-DRB3 0.5719 | STX12 0.5140 | THBS1 0.4991 | Phagosome | 100294318 | 646048 | 646821 | ATP6AP1 | CYBB | HLA-DRB4 | LAMP2 | LOC100133583 | LOC652614 | MRC1L1 | NOX1 | RAB7B | TUBB2C | TUBB4 | TUBB4Q | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa00532 (boxplot) | 21 | 23 | 2.784954746849867 | 0.0026767596986647657 | 0.02130254593520709 | 0.0 | CSGALNACT1 4.1615 | B3GALT6 3.2308 | CHST15 3.0290 | CHSY3 2.8604 | XYLT1 2.3766 | CHSY1 2.2928 | B3GAT1 2.2773 | B3GAT2 2.2607 | UST 2.1005 | CHST14 1.9838 | CHPF 1.7807 | CHPF2 1.7352 | DSE 1.6082 | CHST11 1.5539 | B3GAT3 1.5291 | CHST3 1.5224 | CHST13 1.3835 | CSGALNACT2 1.2240 | CHST12 0.9662 | B4GALT7 0.9508 | XYLT2 0.7501 | Glycosaminoglycan biosynthesis - chondroitin sulfate | CHST7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04720 (boxplot) | 65 | 71 | 2.7837663243854625 | 0.0026865864865521782 | 0.02130254593520709 | 0.0 | CAMK2A 3.5158 | CACNA1C 3.1697 | PLCB3 3.0689 | PLCB2 3.0466 | PRKCB 3.0263 | ITPR1 2.8897 | PRKCA 2.7739 | ITPR2 2.6702 | PRKACG 2.6173 | RAPGEF3 2.5935 | CAMK2D 2.5763 | MAP2K1 2.5626 | ITPR3 2.5571 | RPS6KA2 2.5385 | RPS6KA1 2.5236 | GRIN2D 2.4098 | CAMK4 2.3903 | GRM1 2.3621 | GRIN2B 2.2739 | GRIN2A 2.2237 | MAPK1 2.1844 | PLCB1 2.1804 | CALM1 2.0863 | PRKACB 2.0477 | ADCY1 1.9897 | CAMK2G 1.9776 | PPP3CA 1.9062 | PRKCG 1.8526 | ADCY8 1.7592 | PLCB4 1.7585 | HRAS 1.7462 | MAPK3 1.6641 | CHP2 1.6574 | PPP3R2 1.6507 | KRAS 1.6419 | PPP3R1 1.6073 | CALML5 1.5580 | BRAF 1.5539 | CALM2 1.5462 | EP300 1.5435 | GRIA1 1.5071 | GRM5 1.4972 | PPP1CC 1.4919 | GNAQ 1.3514 | MAP2K2 1.3141 | CREBBP 1.3089 | RAP1A 1.2747 | PPP3CC 1.2662 | RAF1 1.2321 | CALML3 1.1643 | PRKACA 1.1632 | GRIN2C 1.1180 | PPP1R12A 1.1124 | RAP1B 1.0677 | PPP1R1A 0.9983 | GRIA2 0.9944 | CALM3 0.9846 | ATF4 0.9763 | CAMK2B 0.8788 | PPP1CA 0.8778 | PPP1CB 0.8684 | GRIN1 0.8321 | NRAS 0.7783 | CALML6 0.5979 | PPP3CB 0.4679 | Long-term potentiation | ARAF | CHP | PRKX | RPS6KA3 | RPS6KA6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04662 (boxplot) | 72 | 76 | 2.7837188585184203 | 0.0026869796463748763 | 0.02130254593520709 | 0.0 | SYK 4.5860 | CD81 3.9024 | PIK3R5 3.1433 | PRKCB 3.0263 | PLCG2 2.8847 | BLNK 2.8837 | RAC2 2.8280 | CHUK 2.7392 | LYN 2.7044 | RAC1 2.6726 | FOS 2.6457 | MAP2K1 2.5626 | PIK3AP1 2.4828 | VAV1 2.4525 | FCGR2B 2.4253 | NFATC2 2.3660 | VAV2 2.3528 | INPP5D 2.3183 | RASGRP3 2.2666 | NFKBIA 2.2646 | NFATC3 2.2123 | MAPK1 2.1844 | NFAT5 2.0659 | IKBKB 2.0647 | VAV3 1.9834 | CARD11 1.9450 | NFKBIE 1.9165 | PPP3CA 1.9062 | CD22 1.8502 | NFATC1 1.7678 | HRAS 1.7462 | PIK3CD 1.7138 | AKT1 1.7014 | MAPK3 1.6641 | CHP2 1.6574 | PPP3R2 1.6507 | KRAS 1.6419 | PPP3R1 1.6073 | SOS2 1.5974 | PTPN6 1.5953 | LILRB3 1.5847 | IFITM1 1.5763 | MALT1 1.5498 | GSK3B 1.5188 | CR2 1.4837 | PIK3CA 1.4804 | RAC3 1.4192 | PIK3R2 1.4143 | PIK3CB 1.3849 | MAP2K2 1.3141 | CD19 1.2894 | PPP3CC 1.2662 | RAF1 1.2321 | CD79B 1.2213 | NFKB1 1.1903 | PIK3R1 1.1894 | RELA 1.1750 | PIK3CG 1.1284 | DAPP1 1.1158 | NFKBIB 1.1025 | NFATC4 1.0953 | AKT3 0.9935 | JUN 0.9706 | CD72 0.9412 | AKT2 0.9017 | PIK3R3 0.8554 | BCL10 0.8413 | GRB2 0.8222 | NRAS 0.7783 | CD79A 0.6505 | SOS1 0.6101 | PPP3CB 0.4679 | B cell receptor signaling pathway | BTK | CHP | IKBKG | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04144 (boxplot) | 194 | 206 | 2.7059111162615896 | 0.0034058637588376683 | 0.024093332516222025 | 0.0 | AP2M1 4.4336 | TGFB2 3.6070 | GRK5 3.4848 | ARFGAP1 3.3704 | ARRB1 3.2773 | NEDD4L 3.1866 | EEA1 3.1377 | AGAP1 3.1241 | ASAP3 3.1062 | DNAJC6 3.0564 | CHMP4B 3.0036 | CHMP2A 3.0013 | ASAP2 2.8348 | PRKCZ 2.7757 | CHMP6 2.7373 | HLA-B 2.6605 | CXCR1 2.6354 | CXCR2 | PIP5K1B 2.6173 | SH3GL3 2.6098 | IGF1R 2.5914 | SH3GL2 2.5864 | VPS36 2.5544 | PSD3 2.5418 | FGFR4 2.5137 | RHOA 2.5129 | FOLR3 2.4757 | RAB4A 2.4356 | PIP5K1C 2.4349 | SMURF2 2.4340 | RAB11FIP1 2.4250 | GRK4 2.4162 | CLTC 2.3833 | EGFR 2.3734 | VPS37D 2.3662 | DNM2 2.3611 | IQSEC3 2.3517 | RAB11B 2.3503 | SMAP1 2.3499 | GRK6 2.3497 | CLTCL1 2.3471 | FLT1 2.3050 | FOLR1 2.2877 | FOLR2 2.2877 | DAB2 2.2807 | PARD6G 2.2746 | PLD2 2.2532 | TRAF6 2.2343 | HSPA1A 2.2202 | HSPA1B | HSPA1L | EHD1 2.1914 | FGFR2 2.1900 | SMAD7 2.1881 | PML 2.1798 | SMAD3 2.1398 | VPS37A 2.1182 | CHMP2B 2.1074 | CAV2 2.0696 | RUFY1 2.0463 | RAB7A 2.0354 | CSF1R 2.0171 | AP2A2 2.0102 | AP2S1 1.9821 | EGF 1.9813 | DNM3 1.9710 | PLD1 1.9439 | IL2RA 1.9382 | RET 1.9337 | STAM 1.9329 | FAM125B 1.8908 | VPS45 1.8891 | TGFBR2 1.8771 | LDLR 1.8742 | AP2B1 1.8684 | VPS28 1.8595 | EHD4 1.8548 | ERBB4 1.8386 | CDC42 1.8213 | CAV1 1.8147 | GIT1 1.8058 | RABEP1 1.8024 | NTRK1 1.7991 | RAB11FIP3 1.7830 | TSG101 1.7804 | SMAD2 1.7778 | IL2RB 1.7474 | HRAS 1.7462 | CBLB 1.7392 | STAMBP 1.7291 | PARD6B 1.7042 | ARAP1 1.6714 | ARAP3 1.6264 | HLA-A 1.6214 | HLA-F 1.6214 | SRC 1.6146 | RAB11FIP2 1.6050 | IQSEC1 1.5971 | PARD3 1.5924 | RAB31 1.5640 | SMAD6 1.5634 | HLA-C 1.5498 | MDM2 1.5358 | HLA-G 1.5274 | RAB22A 1.5171 | HSPA6 1.5067 | PIP5K1A 1.5040 | PDGFRA 1.4972 | AP2A1 1.4839 | TGFB1 1.4755 | STAM2 1.4742 | FAM125A 1.4370 | PRKCI 1.4300 | CAV3 1.4085 | FGFR3 1.4082 | ADRB2 1.4067 | CLTA 1.4052 | LDLRAP1 1.3995 | HSPA8 1.3974 | CCR5 1.3896 | RNF41 1.3888 | MET 1.3873 | HSPA2 1.3853 | ACAP2 1.3807 | PSD4 1.3799 | HLA-E 1.3786 | SMAP2 1.3592 | NEDD4 1.3588 | VPS4A 1.3431 | ARFGAP2 1.3219 | EPN1 1.3185 | ERBB3 1.3159 | CHMP1B 1.3132 | AGAP2 1.3002 | SH3GL1 1.2999 | GRK1 1.2943 | EHD3 1.2942 | CBLC 1.2803 | ZFYVE9 1.2693 | ARF6 1.2689 | TFRC 1.2478 | SH3GLB1 1.2456 | ARAP2 1.2441 | ADRB1 1.2389 | DNM1L 1.2264 | USP8 1.2135 | ARRB2 1.2047 | ADRBK2 1.1566 | RAB11FIP4 1.1447 | EPS15 1.1363 | KIT 1.1305 | CBL 1.1230 | RAB5A 1.1142 | VTA1 1.0954 | SMURF1 1.0952 | PARD6A 1.0943 | CLTB 1.0901 | CHMP4C 1.0778 | PIP5KL1 1.0776 | ACAP3 1.0603 | TGFBR1 1.0526 | KDR 1.0514 | PSD2 1.0330 | VPS25 1.0160 | ASAP1 0.9944 | CXCR4 0.9401 | DNM1 0.9397 | FOLR4 0.9289 | ARFGAP3 0.9205 | VPS37C 0.9045 | ACAP1 0.8983 | RAB5B 0.8887 | SNF8 0.8864 | EPN3 0.8690 | EHD2 0.8684 | ITCH 0.8652 | ADRBK1 0.8598 | CHMP4A 0.8386 | PDCD6IP 0.8309 | ZFYVE20 0.8179 | TGFB3 0.8111 | RAB5C 0.7943 | F2R 0.7926 | ZFYVE16 0.7775 | VPS37B 0.7635 | RAB11A 0.7293 | RAB11FIP5 0.7233 | PSD 0.7073 | GIT2 0.6694 | CHMP5 0.6670 | WWP1 0.6586 | GRK7 0.6334 | HGS 0.6249 | EPN2 0.5719 | SH3GLB2 0.5546 | VPS4B 0.5144 | ADRB3 0.4798 | Endocytosis | 652671 | 652799 | IL2RG | IQSEC2 | LOC652346 | LOC652614 | SH3KBP1 | VPS24 | |||||||||||
hsa05146 (boxplot) | 102 | 106 | 2.6963611020748592 | 0.0035050813343873166 | 0.024093332516222025 | 0.0 | GNAL 3.9763 | TGFB2 3.6070 | COL4A2 3.5427 | LAMC3 3.2308 | IL12A 3.1864 | PIK3R5 3.1433 | TLR2 3.1008 | ACTN1 3.0707 | PLCB3 3.0689 | PLCB2 3.0466 | PRKCB 3.0263 | COL4A1 2.9190 | PRKCA 2.7739 | PTK2 2.7491 | C8B 2.6531 | IL1R2 2.6332 | PRKACG 2.6173 | LAMC1 2.3490 | ITGB2 2.3293 | TNF 2.2219 | LAMA3 2.2199 | ACTN3 2.2041 | LAMA1 2.1908 | PLCB1 2.1804 | COL11A2 2.1076 | PRKACB 2.0477 | RAB7A 2.0354 | GNA11 2.0156 | ADCY1 1.9897 | NOS2 1.9614 | GNA15 1.9606 | LAMB4 1.9602 | COL4A4 1.8841 | COL5A1 1.8811 | LAMA5 1.8536 | PRKCG 1.8526 | COL2A1 1.8447 | GNAS 1.7902 | GNA14 1.7701 | CXCL1 1.7667 | PLCB4 1.7585 | COL1A1 1.7333 | PIK3CD 1.7138 | SERPINB10 1.6981 | SERPINB2 1.6981 | LAMA2 1.6851 | COL11A1 1.6817 | ARG2 1.6813 | TLR4 1.6570 | HSPB1 1.6447 | IFNG 1.6146 | LAMC2 1.6114 | CD14 1.5535 | VCL 1.5498 | COL3A1 1.4878 | PIK3CA 1.4804 | LAMB3 1.4777 | TGFB1 1.4755 | MUC2 1.4464 | C9 1.4271 | PIK3R2 1.4143 | COL1A2 1.3917 | PIK3CB 1.3849 | ARG1 1.3579 | GNAQ 1.3514 | SERPINB9 1.3495 | CASP3 1.3249 | C8A 1.3135 | CTSG 1.2958 | ACTN2 1.2903 | LAMA4 1.2720 | SERPINB13 1.2654 | COL5A3 1.2647 | LAMB1 1.2559 | COL5A2 1.2531 | FN1 1.2328 | ITGAM 1.2111 | NFKB1 1.1903 | PIK3R1 1.1894 | IL1R1 1.1892 | RELA 1.1750 | PRKACA 1.1632 | SERPINB6 1.1568 | PIK3CG 1.1284 | RAB5A 1.1142 | IL12B 1.0957 | SERPINB1 1.0352 | CSF2 1.0204 | ACTN4 1.0023 | IL1B 0.9755 | LAMB2 0.9751 | IL10 0.9674 | SERPINB3 0.9519 | SERPINB4 0.8983 | RAB5B 0.8887 | CD1D 0.8617 | PIK3R3 0.8554 | IL6 0.8242 | C8G 0.8170 | TGFB3 0.8111 | RAB5C 0.7943 | IL8 0.6227 | Amoebiasis | COL4A6 | PRKX | RAB7B | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa00052 (boxplot) | 25 | 27 | 2.695907081564893 | 0.0035098622609692764 | 0.024093332516222025 | 0.0 | PFKP 4.5795 | LALBA 4.1910 | HK1 3.9094 | GLB1 3.1570 | GAA 2.3728 | HK2 2.2103 | PGM2 1.9602 | AKR1B1 1.8861 | G6PC 1.8551 | PFKM 1.7873 | UGP2 1.6953 | PFKL 1.6836 | GCK 1.6682 | GALK1 1.5923 | GALT 1.5616 | PGM1 1.5240 | B4GALT1 1.4970 | LCT 1.3923 | MGAM 1.3099 | B4GALT2 1.2946 | GALK2 1.2421 | GANC 1.2336 | G6PC2 1.0466 | HK3 0.9706 | GALE 0.6847 | Galactose metabolism | GLA | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05212 (boxplot) | 66 | 71 | 2.6406123758503046 | 0.004137817121565135 | 0.026344102340631358 | 0.0 | TGFB2 3.6070 | PIK3R5 3.1433 | BAD 3.0689 | E2F2 2.9408 | RAC2 2.8280 | CDK4 2.7978 | CHUK 2.7392 | RAC1 2.6726 | MAPK8 2.6033 | MAP2K1 2.5626 | PGF 2.5613 | STAT1 2.5577 | MAPK10 2.5394 | VEGFB 2.4840 | EGFR 2.3734 | TP53 2.3206 | RALGDS 2.2383 | MAPK1 2.1844 | RAD51 2.1552 | SMAD3 2.1398 | RB1 2.1039 | IKBKB 2.0647 | E2F1 2.0545 | RALA 2.0150 | EGF 1.9813 | PLD1 1.9439 | CDKN2A 1.8817 | TGFBR2 1.8771 | E2F3 1.8742 | STAT3 1.8289 | CDC42 1.8213 | SMAD2 1.7778 | PIK3CD 1.7138 | AKT1 1.7014 | MAPK3 1.6641 | KRAS 1.6419 | TGFA 1.6247 | BRAF 1.5539 | PIK3CA 1.4804 | TGFB1 1.4755 | RALBP1 1.4580 | RAC3 1.4192 | PIK3R2 1.4143 | MAPK9 1.4013 | CCND1 1.4000 | PIK3CB 1.3849 | BRCA2 1.3294 | RAF1 1.2321 | NFKB1 1.1903 | PIK3R1 1.1894 | RELA 1.1750 | VEGFA 1.1459 | PIK3CG 1.1284 | SMAD4 1.1109 | CDK6 1.0654 | VEGFC 1.0533 | TGFBR1 1.0526 | CASP9 1.0188 | AKT3 0.9935 | ERBB2 0.9686 | AKT2 0.9017 | PIK3R3 0.8554 | TGFB3 0.8111 | JAK1 0.8097 | BCL2L1 0.7934 | RALB 0.7934 | Pancreatic cancer | ARAF | ARHGEF6 | FIGF | IKBKG | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04930 (boxplot) | 46 | 48 | 2.6131026835297693 | 0.004486217013812355 | 0.0276408854721987 | 0.0 | HK1 3.9094 | MTOR 3.5430 | PRKCD 3.3826 | CACNA1C 3.1697 | PIK3R5 3.1433 | CACNA1A 2.9234 | INSR 2.7897 | PRKCZ 2.7757 | MAPK8 2.6033 | CACNA1E 2.6002 | MAPK10 2.5394 | CACNA1B 2.4467 | PRKCE 2.4343 | TNF 2.2219 | HK2 2.2103 | MAPK1 2.1844 | CACNA1D 2.1133 | IKBKB 2.0647 | CACNA1G 2.0559 | SLC2A2 1.9041 | PIK3CD 1.7138 | GCK 1.6682 | MAPK3 1.6641 | ABCC8 1.5045 | IRS2 1.4841 | PIK3CA 1.4804 | SOCS3 1.4412 | PIK3R2 1.4143 | MAPK9 1.4013 | PIK3CB 1.3849 | SOCS2 1.3744 | ADIPOQ 1.3722 | SLC2A4 1.3574 | MAFA 1.2424 | PIK3R1 1.1894 | PIK3CG 1.1284 | IRS1 1.1009 | INS 1.0072 | HK3 0.9706 | PDX1 0.9289 | PIK3R3 0.8554 | KCNJ11 0.7828 | SOCS1 0.7742 | PKM2 0.7385 | PKLR 0.5988 | SOCS4 0.3630 | Type II diabetes mellitus | IRS4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05140 (boxplot) | 67 | 75 | 2.557013493073434 | 0.005278756113495375 | 0.03150757555242552 | 0.0 | HLA-DQA1 4.6600 | HLA-DQB1 4.6600 | TGFB2 3.6070 | HLA-DRB1 3.2362 | IL12A 3.1864 | TLR2 3.1008 | PRKCB 3.0263 | HLA-DRB5 2.7440 | ITGB1 2.7206 | HLA-DOB 2.6796 | FOS 2.6457 | STAT1 2.5577 | PTGS2 2.5139 | IFNGR1 2.4852 | ITGB2 2.3293 | JAK2 2.2993 | NFKBIA 2.2646 | TRAF6 2.2343 | TNF 2.2219 | MAPK1 2.1844 | HLA-DOA 2.1076 | NOS2 1.9614 | HLA-DRA 1.9559 | MAP3K7 1.9122 | IFNGR2 1.9048 | NCF4 1.7726 | C3 1.7226 | MAPK3 1.6641 | TLR4 1.6570 | FCGR2C 1.6169 | FCGR3B 1.6169 | IFNG 1.6146 | FCGR1A 1.5989 | PTPN6 1.5953 | HLA-DPA1 1.5330 | FCGR3A 1.5067 | CR1 1.4837 | TGFB1 1.4755 | HLA-DPB1 1.3901 | TAB2 1.3718 | HLA-DMA 1.3629 | HLA-DMB | MAPK13 1.3194 | MAPK14 1.3194 | HLA-DQA2 1.2857 | MAPK11 1.2647 | MAPK12 | ITGAM 1.2111 | MYD88 1.1939 | CYBA 1.1917 | NFKB1 1.1903 | NCF2 1.1882 | RELA 1.1750 | NCF1 1.1245 | NFKBIB 1.1025 | IL12B 1.0957 | FCGR2A 1.0661 | TAB1 1.0636 | IRAK4 0.9927 | IL1B 0.9755 | JUN 0.9706 | IL10 0.9674 | IL1A 0.9076 | ITGA4 0.8908 | IL4 0.8297 | TGFB3 0.8111 | JAK1 0.8097 | HLA-DRB3 0.5719 | MARCKSL1 0.1869 | Leishmaniasis | 100294318 | ELK1 | HLA-DRB4 | IRAK1 | LOC100133583 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05210 (boxplot) | 61 | 63 | 2.520989851144815 | 0.005851261362673776 | 0.03386639152335428 | 0.0 | TGFB2 3.6070 | PIK3R5 3.1433 | BAD 3.0689 | APPL1 3.0375 | DCC 2.9809 | BCL2 2.8962 | RAC2 2.8280 | RAC1 2.6726 | FOS 2.6457 | MAPK8 2.6033 | TCF7L2 2.5921 | MAP2K1 2.5626 | MAPK10 2.5394 | RHOA 2.5129 | MSH2 2.3546 | TP53 2.3206 | RALGDS 2.2383 | APC 2.2038 | MAPK1 2.1844 | SMAD3 2.1398 | TCF7L1 1.9555 | AXIN2 1.8914 | TGFBR2 1.8771 | SMAD2 1.7778 | PIK3CD 1.7138 | AKT1 1.7014 | AXIN1 1.6664 | MAPK3 1.6641 | KRAS 1.6419 | MSH3 1.6082 | CYCS 1.5581 | BRAF 1.5539 | APC2 1.5322 | GSK3B 1.5188 | PIK3CA 1.4804 | TGFB1 1.4755 | BIRC5 1.4636 | BAX 1.4526 | RAC3 1.4192 | PIK3R2 1.4143 | MAPK9 1.4013 | CCND1 1.4000 | PIK3CB 1.3849 | CASP3 1.3249 | MSH6 1.2485 | RAF1 1.2321 | MLH1 1.2000 | PIK3R1 1.1894 | PIK3CG 1.1284 | TCF7 1.1162 | SMAD4 1.1109 | TGFBR1 1.0526 | MYC 1.0337 | CASP9 1.0188 | AKT3 0.9935 | JUN 0.9706 | CTNNB1 0.9144 | AKT2 0.9017 | LEF1 0.8952 | PIK3R3 0.8554 | TGFB3 0.8111 | Colorectal cancer | ARAF | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04320 (boxplot) | 24 | 26 | 2.4485666592573856 | 0.0071712943973525345 | 0.04028580087924512 | 0.0 | ETV6 3.7270 | PIWIL2 3.4870 | PIWIL1 2.6440 | MAP2K1 2.5626 | EGFR 2.3734 | MAPK1 2.1844 | NOTCH3 2.1271 | SPIRE1 2.0611 | SPIRE2 1.9598 | NOTCH4 1.9559 | CPEB1 1.9496 | FMN2 1.9194 | ETV7 1.8339 | PIWIL4 1.7742 | MAPK3 1.6641 | NOTCH1 1.6513 | KRAS 1.6419 | NOTCH2 1.6146 | SOS2 1.5974 | PIWIL3 1.5624 | ETS1 1.2536 | GRB2 0.8222 | ETS2 0.7387 | SOS1 0.6101 | Dorso-ventral axis formation | LOC652554 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04670 (boxplot) | 107 | 119 | 2.4442422791157585 | 0.007257837451569271 | 0.04028580087924512 | 0.0 | ACTB 3.7300 | MYL12A 3.3308 | MYL12B | CTNNA2 3.2208 | PIK3R5 3.1433 | ACTN1 3.0707 | CLDN20 3.0503 | CLDN5 3.0479 | PRKCB 3.0263 | CLDN16 2.9594 | PLCG2 2.8847 | RAC2 2.8280 | PRKCA 2.7739 | PTK2 2.7491 | ITGB1 2.7206 | RAC1 2.6726 | PTK2B 2.6525 | RAPGEF4 2.6470 | RAPGEF3 2.5935 | RHOA 2.5129 | PLCG1 2.5010 | ACTG1 2.4632 | BCAR1 2.4612 | VAV1 2.4525 | MMP9 2.4506 | VAV2 2.3528 | ITGB2 2.3293 | ACTN3 2.2041 | CTNNA3 2.1832 | VASP 2.1552 | NOX3 2.1286 | ROCK2 2.0579 | CXCL12 2.0554 | GNAI3 2.0223 | CLDN22 2.0102 | VAV3 1.9834 | VCAM1 1.9817 | PTPN11 1.9382 | MYL5 1.9355 | PRKCG 1.8526 | CDC42 1.8213 | CLDN14 1.8130 | JAM2 1.7762 | NCF4 1.7726 | ITK 1.7404 | CLDN19 1.7298 | PIK3CD 1.7138 | CLDN18 1.6972 | MYL7 1.6682 | CLDN1 1.6284 | GNAI1 1.6096 | MLLT4 1.5911 | CLDN10 1.5844 | VCL 1.5498 | JAM3 1.5126 | PIK3CA 1.4804 | ESAM 1.4708 | PIK3R2 1.4143 | CLDN17 1.4118 | EZR 1.4086 | PIK3CB 1.3849 | TXK 1.3610 | CDH5 1.3421 | CLDN8 1.3417 | ITGAL 1.3308 | MAPK13 1.3194 | MAPK14 1.3194 | ACTN2 1.2903 | ROCK1 1.2802 | RAP1A 1.2747 | MYL9 1.2691 | MAPK11 1.2647 | MAPK12 | THY1 1.2531 | PECAM1 1.2503 | ARHGAP5 1.2312 | CLDN11 1.2257 | CLDN23 1.2160 | CTNND1 1.2139 | ITGAM 1.2111 | CYBA 1.1917 | PIK3R1 1.1894 | NCF2 1.1882 | SIPA1 1.1750 | CLDN3 1.1649 | PIK3CG 1.1284 | MMP2 1.1263 | NCF1 1.1245 | OCLN 1.1211 | MYL10 1.0953 | RAP1B 1.0677 | MYL2 1.0664 | F11R 1.0618 | MYLPF 1.0237 | RHOH 1.0187 | ACTN4 1.0023 | ICAM1 0.9880 | CTNNA1 0.9825 | PXN 0.9662 | CXCR4 0.9401 | CLDN4 0.9151 | CTNNB1 0.9144 | RASSF5 0.9059 | ITGA4 0.8908 | PIK3R3 0.8554 | CLDN7 0.8542 | CLDN6 0.5071 | CLDN9 | CLDN15 0.4585 | GNAI2 0.3699 | Leukocyte transendothelial migration | 646048 | 646821 | CD99 | CLDN2 | CYBB | GRLF1 | MSN | NOX1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05223 (boxplot) | 53 | 55 | 2.433989634367414 | 0.0074667113669169005 | 0.04028580087924512 | 0.0 | FHIT 5.0721 | PIK3R5 3.1433 | BAD 3.0689 | PRKCB 3.0263 | E2F2 2.9408 | PLCG2 2.8847 | CDK4 2.7978 | PRKCA 2.7739 | MAP2K1 2.5626 | PLCG1 2.5010 | RXRG 2.4598 | EGFR 2.3734 | TP53 2.3206 | RXRA 2.2312 | MAPK1 2.1844 | RXRB 2.1076 | RB1 2.1039 | E2F1 2.0545 | EGF 1.9813 | RARB 1.9500 | CDKN2A 1.8817 | E2F3 1.8742 | PRKCG 1.8526 | HRAS 1.7462 | PIK3CD 1.7138 | AKT1 1.7014 | MAPK3 1.6641 | KRAS 1.6419 | TGFA 1.6247 | SOS2 1.5974 | BRAF 1.5539 | PIK3CA 1.4804 | STK4 1.4334 | PIK3R2 1.4143 | CCND1 1.4000 | PIK3CB 1.3849 | FOXO3 1.3195 | MAP2K2 1.3141 | RAF1 1.2321 | PIK3R1 1.1894 | PIK3CG 1.1284 | CDK6 1.0654 | CASP9 1.0188 | AKT3 0.9935 | ERBB2 0.9686 | RASSF5 0.9059 | PDPK1 0.9045 | AKT2 0.9017 | PIK3R3 0.8554 | GRB2 0.8222 | NRAS 0.7783 | SOS1 0.6101 | RASSF1 0.3433 | Non-small cell lung cancer | ARAF | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04722 (boxplot) | 119 | 127 | 2.3765958355197716 | 0.008736610868216532 | 0.0450998020494421 | 0.0 | NTF3 3.7721 | CAMK2A 3.5158 | MAP2K5 3.4532 | PRKCD 3.3826 | PIK3R5 3.1433 | BAD 3.0689 | BCL2 2.8962 | PLCG2 2.8847 | BDNF 2.7240 | RAC1 2.6726 | ARHGDIA 2.6482 | SHC4 2.6119 | MAPK8 2.6033 | NGF 2.5955 | CAMK2D 2.5763 | MAP2K1 2.5626 | MAPK10 2.5394 | RPS6KA2 2.5385 | RPS6KA1 2.5236 | RHOA 2.5129 | PLCG1 2.5010 | SH2B2 2.4671 | NGFR 2.4478 | CAMK4 2.3903 | TP53 2.3206 | NFKBIA 2.2646 | NTRK3 2.2632 | TRAF6 2.2343 | SORT1 2.2269 | MAPK1 2.1844 | NTRK2 2.1710 | KIDINS220 2.0947 | CALM1 2.0863 | GAB1 2.0731 | IKBKB 2.0647 | RAPGEF1 1.9957 | PSEN1 1.9792 | CAMK2G 1.9776 | PTPN11 1.9382 | IRAK2 1.9197 | NFKBIE 1.9165 | RPS6KA5 1.8690 | FASLG 1.8661 | MAP3K5 1.8395 | CDC42 1.8213 | MAP3K1 1.8142 | NTRK1 1.7991 | RIPK2 1.7610 | HRAS 1.7462 | YWHAG 1.7338 | IRAK3 1.7279 | PIK3CD 1.7138 | AKT1 1.7014 | MAPK3 1.6641 | YWHAB 1.6533 | KRAS 1.6419 | RPS6KA4 1.6180 | SOS2 1.5974 | YWHAE 1.5943 | CALML5 1.5580 | BRAF 1.5539 | CALM2 1.5462 | GSK3B 1.5188 | ABL1 1.5088 | SHC3 1.4919 | IRS2 1.4841 | PIK3CA 1.4804 | CSK 1.4742 | BAX 1.4526 | YWHAH 1.4476 | SHC2 1.4331 | NTF4 1.4312 | CRK 1.4166 | PIK3R2 1.4143 | MAPK9 1.4013 | PIK3CB 1.3849 | PDK1 1.3573 | FOXO3 1.3195 | MAPK13 1.3194 | MAPK14 1.3194 | MAP2K2 1.3141 | RAP1A 1.2747 | YWHAQ 1.2716 | MAPK11 1.2647 | MAPK12 | RAF1 1.2321 | ARHGDIB 1.2240 | NFKB1 1.1903 | PIK3R1 1.1894 | MAP2K7 1.1842 | RELA 1.1750 | CALML3 1.1643 | ZNF274 1.1434 | PIK3CG 1.1284 | SH2B3 1.1177 | NFKBIB 1.1025 | IRS1 1.1009 | TP73 1.0981 | MAPKAPK2 1.0826 | RAP1B 1.0677 | PRDM4 1.0659 | CRKL 1.0292 | AKT3 0.9935 | IRAK4 0.9927 | CALM3 0.9846 | ATF4 0.9763 | JUN 0.9706 | YWHAZ 0.9535 | MAP3K3 0.9348 | AKT2 0.9017 | CAMK2B 0.8788 | PIK3R3 0.8554 | FRS2 0.8511 | GRB2 0.8222 | NRAS 0.7783 | SH2B1 0.6912 | SHC1 0.6411 | SOS1 0.6101 | CALML6 0.5979 | MAPK7 0.2593 | Neurotrophin signaling pathway | IRAK1 | IRS4 | MAGED1 | NGFRAP1 | RPS6KA3 | RPS6KA6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa00051 (boxplot) | 32 | 35 | 2.368162996616274 | 0.008938329111715992 | 0.0450998020494421 | 0.0 | PFKP 4.5795 | HK1 3.9094 | TSTA3 3.2304 | FPGT 3.0929 | FBP1 2.8063 | MTMR2 2.5058 | MTMR7 2.3882 | PFKFB4 2.3743 | HK2 2.2103 | GMDS 2.1281 | PFKFB3 2.0571 | PMM2 2.0562 | AKR1B1 1.8861 | PFKM 1.7873 | GMPPA 1.7807 | MTMR6 1.7160 | PFKL 1.6836 | FBP2 1.6503 | AKR1B10 1.6148 | ALDOA 1.3747 | PFKFB2 1.3584 | GMPPB 1.3022 | KHK 1.2767 | TPI1 1.1217 | SORD 1.1005 | ALDOB 1.0582 | PMM1 0.9880 | HK3 0.9706 | PHPT1 0.8861 | FUK 0.8768 | MPI 0.7762 | ALDOC 0.5996 | Fructose and mannose metabolism | MTMR1 | PFKFB1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05214 (boxplot) | 64 | 66 | 2.353380648094461 | 0.009301789525027915 | 0.04555491793026492 | 0.0 | MTOR 3.5430 | CAMK2A 3.5158 | PIK3R5 3.1433 | PRKCB 3.0263 | E2F2 2.9408 | PLCG2 2.8847 | CDK4 2.7978 | PRKCA 2.7739 | SHC4 2.6119 | IGF1R 2.5914 | CAMK2D 2.5763 | MAP2K1 2.5626 | PLCG1 2.5010 | EGFR 2.3734 | TP53 2.3206 | MAPK1 2.1844 | RB1 2.1039 | CALM1 2.0863 | E2F1 2.0545 | PDGFA 2.0484 | EGF 1.9813 | CAMK2G 1.9776 | IGF1 1.9296 | CDKN2A 1.8817 | E2F3 1.8742 | PRKCG 1.8526 | PDGFB 1.8438 | HRAS 1.7462 | PIK3CD 1.7138 | AKT1 1.7014 | MAPK3 1.6641 | KRAS 1.6419 | TGFA 1.6247 | SOS2 1.5974 | CALML5 1.5580 | BRAF 1.5539 | CALM2 1.5462 | MDM2 1.5358 | PDGFRA 1.4972 | SHC3 1.4919 | PIK3CA 1.4804 | PDGFRB 1.4665 | SHC2 1.4331 | PIK3R2 1.4143 | CCND1 1.4000 | PIK3CB 1.3849 | MAP2K2 1.3141 | CDKN1A 1.2652 | RAF1 1.2321 | PIK3R1 1.1894 | CALML3 1.1643 | PIK3CG 1.1284 | CDK6 1.0654 | AKT3 0.9935 | CALM3 0.9846 | AKT2 0.9017 | PTEN 0.8976 | CAMK2B 0.8788 | PIK3R3 0.8554 | GRB2 0.8222 | NRAS 0.7783 | SHC1 0.6411 | SOS1 0.6101 | CALML6 0.5979 | Glioma | ARAF |