data type: SNP
method: ZSCORE
K: 2
cutoff: 0.05
tolerance: 0%
Genes with the 1st to the k-th largest or smallest p-values: Exclude
Take common log and negated the p-values of genes: Yes
set name | gene count | set size | z-score | p-value | corrected p-value | FDR | gene symbols | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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synaptic membrane (boxplot) | 198 | 204 | 6.92373429213002 | 2.199351811782435E-12 | 1.0746032952368978E-8 | 0.0 | GPHN 5.9364 | GRID1 5.7829 | GRIK4 3.9399 | DLGAP1 3.9176 | PICALM 3.8576 | PDE2A 3.7330 | GABRG3 3.6968 | NRXN1 3.6097 | GRIA4 3.3765 | ERC2 3.3555 | CHRM4 3.3170 | GRIK2 3.2889 | SYNE1 3.2809 | PSD3 3.2638 | DLG2 3.2580 | ERBB2 3.2295 | GRM8 3.2143 | GRIN3A 3.1467 | SHANK1 3.1256 | DNM2 3.0383 | GRID2 3.0003 | GABRB3 2.9924 | ANKS1B 2.9443 | SYNPO 2.9309 | HTR3B 2.8560 | GRM7 2.8268 | NLGN1 2.7866 | LRFN2 2.7641 | LIN7B 2.7612 | UTRN 2.7531 | SYT1 2.6792 | DLGAP3 2.6740 | KCTD16 2.6397 | PDLIM5 2.6326 | GABRR3 2.6005 | NETO1 2.5980 | MUSK 2.5943 | GLRA2 2.5894 | SRGAP2 2.5232 | AKAP1 2.5165 | GRID2IP 2.4971 | DLGAP2 2.4513 | SNAP91 2.4483 | GABRA3 2.4286 | GRIA3 2.4068 | SHANK2 2.3841 | HTR3E 2.3683 | NPTN 2.3588 | CLSTN2 2.3525 | HTR3C 2.3466 | HOMER2 2.3096 | NLGN4X 2.3043 | CHRNB1 2.2963 | GRIN2B 2.2951 | GRIP1 2.2692 | UNC13C 2.2620 | GABBR2 2.2343 | ERC1 2.2200 | GABRG1 2.2106 | CPEB1 2.2018 | TRPV1 2.1980 | HOMER1 2.1943 | CAMK2A 2.1496 | SNCAIP 2.1411 | ARC 2.1147 | CNIH2 2.1101 | GRIN2A 2.0931 | GABRA5 2.0812 | MPDZ 2.0535 | CHRNA10 2.0484 | SHANK3 2.0446 | IL1RAPL1 2.0206 | DISC1 2.0102 | ATAD1 2.0096 | LIN7A 2.0092 | GRIK3 2.0041 | DTNBP1 2.0039 | GABRQ 1.9995 | RGS14 1.9785 | GRIN2C 1.9757 | SRCIN1 1.9663 | GABBR1 1.9622 | FAIM2 1.9527 | P2RX1 1.9501 | CHRM3 1.9459 | OPRD1 1.9420 | RIMS1 1.9395 | SCRIB 1.9095 | CNIH3 1.8983 | STRN 1.8799 | CHRM2 1.8694 | DLG1 1.8617 | CHRNA2 1.8484 | SHC4 1.8427 | SYNDIG1 1.8308 | GRIK1 1.8243 | GABRG2 1.8133 | SEPT3 1.7964 | RAPSN 1.7860 | SLC1A2 1.7777 | GRIK5 1.7636 | CHRND 1.7516 | CLSTN1 1.7408 | DLG4 1.7370 | TANC1 1.7362 | GABRR1 1.7119 | GABRB2 1.7081 | ADORA1 1.7070 | EPHA7 1.6962 | ZNRF2 1.6826 | UNC13A 1.6800 | CACNG5 1.6745 | EPHA4 1.6721 | CHRNA7 1.6719 | GABRB1 1.6717 | GLRA3 1.6714 | ARHGAP32 1.6693 | KCTD8 1.6688 | CAMK2N1 1.6619 | GRM1 1.6533 | CHRM5 1.6228 | NCS1 1.6216 | GOPC 1.6059 | RIMS2 1.5957 | ZACN 1.5950 | SEMA4C 1.5761 | GABRA1 1.5731 | CDK5 1.5715 | SSPN 1.5492 | FBXO45 1.5364 | CHRNA9 1.5108 | LRRC4B 1.4908 | CHRNG 1.4825 | CABP1 1.4653 | CHRNE 1.4611 | MINK1 | LZTS1 1.4506 | GLRA1 1.4443 | F2R 1.4291 | CNKSR2 1.4215 | DNAJA3 1.4206 | CASK 1.4083 | PICK1 1.3992 | LRRC7 1.3949 | LRRC4 1.3922 | GRIN2D 1.3766 | LRFN3 1.3681 | DENND1A 1.3576 | GRM3 1.3280 | CHRNA1 1.3109 | ADORA2A 1.3027 | GABRD 1.2730 | KCTD12 1.2705 | CACNG8 1.2699 | GRIN1 1.2637 | GABRP 1.2409 | SEMA4F 1.2167 | GABRA2 1.2072 | GLRA4 1.2033 | CHRNA4 1.2001 | CHRNA3 1.1921 | CHRNB4 | KLHL17 1.1909 | GLRB 1.1896 | HTR3A 1.1787 | GABRE 1.1782 | HOMER3 1.1653 | FOSL1 1.1638 | CHRNA5 1.1534 | GRIA1 1.1475 | MET 1.1441 | SIPA1L1 1.1047 | GRM2 1.0960 | GRIN3B 1.0627 | MTMR2 1.0519 | PCDH8 1.0462 | CHRM1 1.0409 | ERBB3 1.0409 | PRR7 1.0225 | PJA2 1.0179 | GRIA2 0.9514 | CHRNB2 0.9425 | ACHE 0.9394 | CLSTN3 0.8999 | GABRR2 0.8946 | GAD2 0.8924 | LRFN1 0.8886 | GABRA6 0.8703 | SYP 0.8425 | GRASP 0.8192 | P2RY1 0.7649 | GABRA4 0.7578 | NLGN2 0.6604 | LRRTM2 0.6474 | LIN7C 0.6405 | MAGEE1 0.6403 | L1CAM 0.6002 | SNTA1 0.5644 | CHRNA6 0.3958 | CHRNB3 0.3372 | CHRFAM7A | CHRNA7-2 | NLGN4Y | PROSAPIP1 | |||
postsynaptic membrane (boxplot) | 171 | 177 | 6.487867480784531 | 4.352962434950314E-11 | 1.0634287228583617E-7 | 0.0 | GPHN 5.9364 | GRID1 5.7829 | GRIK4 3.9399 | DLGAP1 3.9176 | PICALM 3.8576 | GABRG3 3.6968 | GRIA4 3.3765 | CHRM4 3.3170 | GRIK2 3.2889 | SYNE1 3.2809 | PSD3 3.2638 | DLG2 3.2580 | ERBB2 3.2295 | GRIN3A 3.1467 | SHANK1 3.1256 | DNM2 3.0383 | GRID2 3.0003 | GABRB3 2.9924 | ANKS1B 2.9443 | SYNPO 2.9309 | HTR3B 2.8560 | GRM7 2.8268 | NLGN1 2.7866 | LRFN2 2.7641 | LIN7B 2.7612 | UTRN 2.7531 | DLGAP3 2.6740 | KCTD16 2.6397 | PDLIM5 2.6326 | GABRR3 2.6005 | NETO1 2.5980 | MUSK 2.5943 | GLRA2 2.5894 | SRGAP2 2.5232 | AKAP1 2.5165 | GRID2IP 2.4971 | DLGAP2 2.4513 | SNAP91 2.4483 | GABRA3 2.4286 | GRIA3 2.4068 | SHANK2 2.3841 | HTR3E 2.3683 | CLSTN2 2.3525 | HTR3C 2.3466 | HOMER2 2.3096 | NLGN4X 2.3043 | CHRNB1 2.2963 | GRIN2B 2.2951 | GRIP1 2.2692 | GABBR2 2.2343 | GABRG1 2.2106 | CPEB1 2.2018 | TRPV1 2.1980 | HOMER1 2.1943 | ARC 2.1147 | CNIH2 2.1101 | GRIN2A 2.0931 | GABRA5 2.0812 | MPDZ 2.0535 | CHRNA10 2.0484 | SHANK3 2.0446 | IL1RAPL1 2.0206 | DISC1 2.0102 | ATAD1 2.0096 | LIN7A 2.0092 | GRIK3 2.0041 | DTNBP1 2.0039 | GABRQ 1.9995 | RGS14 1.9785 | GRIN2C 1.9757 | SRCIN1 1.9663 | GABBR1 1.9622 | FAIM2 1.9527 | P2RX1 1.9501 | CHRM3 1.9459 | OPRD1 1.9420 | SCRIB 1.9095 | CNIH3 1.8983 | STRN 1.8799 | CHRM2 1.8694 | DLG1 1.8617 | CHRNA2 1.8484 | SHC4 1.8427 | SYNDIG1 1.8308 | GRIK1 1.8243 | GABRG2 1.8133 | RAPSN 1.7860 | GRIK5 1.7636 | CHRND 1.7516 | CLSTN1 1.7408 | DLG4 1.7370 | TANC1 1.7362 | GABRR1 1.7119 | GABRB2 1.7081 | ADORA1 1.7070 | EPHA7 1.6962 | CACNG5 1.6745 | EPHA4 1.6721 | CHRNA7 1.6719 | GABRB1 1.6717 | GLRA3 1.6714 | ARHGAP32 1.6693 | KCTD8 1.6688 | CAMK2N1 1.6619 | CHRM5 1.6228 | NCS1 1.6216 | GOPC 1.6059 | ZACN 1.5950 | SEMA4C 1.5761 | GABRA1 1.5731 | CDK5 1.5715 | SSPN 1.5492 | FBXO45 1.5364 | CHRNA9 1.5108 | CHRNG 1.4825 | CABP1 1.4653 | CHRNE 1.4611 | MINK1 | LZTS1 1.4506 | GLRA1 1.4443 | F2R 1.4291 | CNKSR2 1.4215 | DNAJA3 1.4206 | LRRC7 1.3949 | LRRC4 1.3922 | GRIN2D 1.3766 | LRFN3 1.3681 | GRM3 1.3280 | CHRNA1 1.3109 | ADORA2A 1.3027 | GABRD 1.2730 | KCTD12 1.2705 | CACNG8 1.2699 | GRIN1 1.2637 | GABRP 1.2409 | SEMA4F 1.2167 | GABRA2 1.2072 | GLRA4 1.2033 | CHRNA4 1.2001 | CHRNA3 1.1921 | CHRNB4 | KLHL17 1.1909 | GLRB 1.1896 | HTR3A 1.1787 | GABRE 1.1782 | HOMER3 1.1653 | CHRNA5 1.1534 | GRIA1 1.1475 | MET 1.1441 | SIPA1L1 1.1047 | GRIN3B 1.0627 | PCDH8 1.0462 | CHRM1 1.0409 | ERBB3 1.0409 | PRR7 1.0225 | PJA2 1.0179 | GRIA2 0.9514 | CHRNB2 0.9425 | ACHE 0.9394 | CLSTN3 0.8999 | GABRR2 0.8946 | LRFN1 0.8886 | GABRA6 0.8703 | GRASP 0.8192 | P2RY1 0.7649 | GABRA4 0.7578 | NLGN2 0.6604 | LRRTM2 0.6474 | LIN7C 0.6405 | MAGEE1 0.6403 | SNTA1 0.5644 | CHRNA6 0.3958 | CHRNB3 0.3372 | CHRFAM7A | CHRNA7-2 | NLGN4Y | PROSAPIP1 | ||||||||||||||||||||||||||||||
axon part (boxplot) | 119 | 121 | 5.489398843861899 | 2.0165200620425594E-8 | 3.284239007713315E-5 | 0.0 | YWHAE 4.5001 | SEPT7 4.3221 | GRIK4 3.9399 | SCN2A 3.6519 | NRXN1 3.6097 | GHRH 3.4507 | AMPH 3.4482 | GRIA4 3.3765 | CHRM4 3.3170 | GRIK2 3.2889 | MYO1D 3.2744 | DLG2 3.2580 | FKBP4 3.2506 | CNTNAP2 3.1556 | MBP 3.0687 | ROBO2 3.0085 | NFASC 2.9513 | PTPRN2 2.8388 | SPOCK1 2.7896 | SYNJ2 2.7782 | SLC18A3 2.7603 | DLGAP2 2.4513 | SNCG 2.4359 | ATP6V0D1 2.4205 | KCNC4 2.3714 | NEFH 2.3691 | GPM6A 2.3326 | BIN1 2.3168 | MAPK8IP1 2.3164 | GRIN2B 2.2951 | CNTN2 2.2820 | PRSS12 2.2794 | SEPT5 2.2712 | TUBB4A 2.2033 | ROBO1 2.1673 | PCSK1 2.1639 | SCN8A 2.1612 | CST3 2.1381 | GRIN2A 2.0931 | SLC18A2 2.0880 | CCKAR 2.0865 | MAP3K12 2.0825 | DISC1 2.0102 | GRIK3 2.0041 | DTNBP1 2.0039 | TH 1.9742 | GABBR1 1.9622 | MAPK1 1.9571 | CHRM3 1.9459 | OPRD1 1.9420 | SNCB 1.9380 | HTR1A 1.9289 | CYP19A1 1.9264 | OXT 1.9195 | KCNAB2 1.9081 | MAG 1.8819 | KCNA2 1.8775 | CHRM2 1.8694 | SPTBN4 1.8647 | DLG1 1.8617 | P2RX7 1.8574 | ESR1 1.8508 | UCN3 1.8448 | DRD4 1.8319 | GRIK1 1.8243 | DBH 1.8135 | SEPT6 1.7947 | SLC1A2 1.7777 | MAPK8IP3 1.7605 | DLG4 1.7370 | TANC1 1.7362 | KCNA1 1.7305 | PFN2 1.7072 | ADORA1 1.7070 | DPYSL2 1.6469 | SLC32A1 1.6305 | DRD2 1.5853 | HCN4 1.5579 | MAP2K1 1.5376 | NEFM 1.5303 | APC 1.5096 | P2RX4 1.5095 | SNAP25 1.4539 | GOT1 1.4481 | LDLRAP1 1.4279 | P2RX3 1.3783 | CRHR1 1.3545 | NEFL 1.3454 | DST 1.3319 | ADORA2A 1.3027 | CNTNAP1 1.2662 | GRIN1 1.2637 | PRPH 1.2535 | CDH1 1.2150 | TRPV2 1.1404 | ILK 1.1347 | CABP4 1.1126 | MYLK2 1.0997 | GAN 1.0983 | CRHBP 1.0855 | CHRM1 1.0409 | HAP1 1.0381 | ERMN 1.0218 | AAK1 0.9958 | CAD 0.9730 | GRIA2 0.9514 | CCK 0.9390 | PEBP1 0.9211 | NMU 0.8991 | OPHN1 0.8605 | UCN 0.8158 | PAFAH1B1 0.8148 | CALCA 0.8098 | KCNC3 0.8056 | SMURF1 0.7898 | DIXDC1 0.6947 | DAG1 0.6937 | INA 0.6110 | L1CAM 0.6002 | DKFZp586I031 | estrogen receptor | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
dendritic spine (boxplot) | 148 | 151 | 5.162737816172141 | 1.21681947296004E-7 | 1.486344986220689E-4 | 0.0 | DLGAP1 3.9176 | MAGI2 3.4637 | DNM3 3.4277 | GRIA4 3.3765 | CHRM4 3.3170 | ERBB4 3.2809 | PSD3 3.2638 | DLG2 3.2580 | SEPT11 3.2438 | GRIN3A 3.1467 | SHANK1 3.1256 | DNM2 3.0383 | GRID2 3.0003 | ANKS1B 2.9443 | SYNPO 2.9309 | CACNA1C 2.8754 | SPOCK1 2.7896 | NLGN1 2.7866 | SLC8A1 2.7718 | LIN7B 2.7612 | ASIC2 2.7474 | DLGAP3 2.6740 | PDLIM5 2.6326 | NETO1 2.5980 | IGF2BP1 2.5771 | ADD1 2.5292 | SRGAP2 2.5232 | DLGAP2 2.4513 | SNAP91 2.4483 | CTNND2 2.4273 | SHANK2 2.3841 | GPM6A 2.3326 | HOMER2 2.3096 | NLGN4X 2.3043 | NOS1 2.3035 | GRIN2B 2.2951 | CALD1 2.2528 | MAP1B 2.2447 | CPEB1 2.2018 | TRPV1 2.1980 | HOMER1 2.1943 | SLC1A3 2.1895 | APP 2.1303 | ARC 2.1147 | CNIH2 2.1101 | GRIN2A 2.0931 | NR3C1 2.0926 | MPDZ 2.0535 | PPP1R9A 2.0454 | SHANK3 2.0446 | MYL7 2.0341 | MYO5B 2.0328 | DDN 2.0180 | DISC1 2.0102 | LIN7A 2.0092 | DTNBP1 2.0039 | RGS14 1.9785 | GRM5 1.9765 | GRIN2C 1.9757 | AXIN1 1.9756 | SRCIN1 1.9663 | GABBR1 1.9622 | NCOA2 1.9449 | CYP19A1 1.9264 | EXOC4 1.9205 | SLC8A3 1.9072 | STRN 1.8799 | MAPK8IP2 1.8627 | DLG1 1.8617 | DRD4 1.8319 | SYNDIG1 1.8308 | LPAR1 1.8285 | PPP1R9B 1.8018 | YWHAZ 1.7916 | PTPRO 1.7894 | SLC1A2 1.7777 | ADAM10 1.7625 | DLG4 1.7370 | TANC1 1.7362 | ACTN2 1.7215 | PALM 1.7163 | SHISA9 1.7162 | ADORA1 1.7070 | RAPGEF4 1.6971 | CACNG5 1.6745 | EPHA4 1.6721 | ARHGAP32 1.6693 | CAMK2N1 1.6619 | GRM1 1.6533 | NCS1 1.6216 | MIB1 1.6201 | GOPC 1.6059 | LYN 1.5986 | DRD2 1.5853 | SEMA4C 1.5761 | CDK5 1.5715 | FRMPD4 1.5631 | GIPC1 1.5412 | FBXO45 1.5364 | P2RX4 1.5095 | MYH10 1.4980 | SLC8A2 1.4933 | EPS8 1.4871 | DRD1 1.4777 | CABP1 1.4653 | MINK1 1.4611 | LZTS1 1.4506 | DLG3 1.3998 | PICK1 1.3992 | LRRC7 1.3949 | P2RX3 1.3783 | AXIN2 1.3665 | PLCB4 1.3630 | ALS2 1.3539 | GRM3 1.3280 | ADORA2A 1.3027 | KCND2 1.2892 | CACNG8 1.2699 | GRIN1 1.2637 | CHRNA3 1.1921 | KLHL17 1.1909 | HOMER3 1.1653 | GRIA1 1.1475 | MET 1.1441 | PTK2B 1.1280 | SIPA1L1 1.1047 | MYLK2 1.0997 | PALMD 1.0917 | LPHN1 1.0739 | ADRBK1 1.0662 | MTMR2 1.0519 | ADRB2 1.0467 | CHRM1 1.0409 | PJA2 1.0179 | CANX 0.9986 | GRIA2 0.9514 | FBXO2 0.9163 | CDK5R1 0.9094 | CRIPT 0.8965 | LRFN1 0.8886 | OPHN1 0.8605 | DBNL 0.8579 | P2RX6 0.7959 | SHARPIN 0.7933 | P2RY1 0.7649 | LIN7C 0.6405 | STRN4 0.5986 | ATP1A2 0.4943 | MT-ND2 | NLGN4Y | PROSAPIP1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
neuron spine (boxplot) | 148 | 151 | 5.162737816172141 | 1.21681947296004E-7 | 1.486344986220689E-4 | 0.0 | DLGAP1 3.9176 | MAGI2 3.4637 | DNM3 3.4277 | GRIA4 3.3765 | CHRM4 3.3170 | ERBB4 3.2809 | PSD3 3.2638 | DLG2 3.2580 | SEPT11 3.2438 | GRIN3A 3.1467 | SHANK1 3.1256 | DNM2 3.0383 | GRID2 3.0003 | ANKS1B 2.9443 | SYNPO 2.9309 | CACNA1C 2.8754 | SPOCK1 2.7896 | NLGN1 2.7866 | SLC8A1 2.7718 | LIN7B 2.7612 | ASIC2 2.7474 | DLGAP3 2.6740 | PDLIM5 2.6326 | NETO1 2.5980 | IGF2BP1 2.5771 | ADD1 2.5292 | SRGAP2 2.5232 | DLGAP2 2.4513 | SNAP91 2.4483 | CTNND2 2.4273 | SHANK2 2.3841 | GPM6A 2.3326 | HOMER2 2.3096 | NLGN4X 2.3043 | NOS1 2.3035 | GRIN2B 2.2951 | CALD1 2.2528 | MAP1B 2.2447 | CPEB1 2.2018 | TRPV1 2.1980 | HOMER1 2.1943 | SLC1A3 2.1895 | APP 2.1303 | ARC 2.1147 | CNIH2 2.1101 | GRIN2A 2.0931 | NR3C1 2.0926 | MPDZ 2.0535 | PPP1R9A 2.0454 | SHANK3 2.0446 | MYL7 2.0341 | MYO5B 2.0328 | DDN 2.0180 | DISC1 2.0102 | LIN7A 2.0092 | DTNBP1 2.0039 | RGS14 1.9785 | GRM5 1.9765 | GRIN2C 1.9757 | AXIN1 1.9756 | SRCIN1 1.9663 | GABBR1 1.9622 | NCOA2 1.9449 | CYP19A1 1.9264 | EXOC4 1.9205 | SLC8A3 1.9072 | STRN 1.8799 | MAPK8IP2 1.8627 | DLG1 1.8617 | DRD4 1.8319 | SYNDIG1 1.8308 | LPAR1 1.8285 | PPP1R9B 1.8018 | YWHAZ 1.7916 | PTPRO 1.7894 | SLC1A2 1.7777 | ADAM10 1.7625 | DLG4 1.7370 | TANC1 1.7362 | ACTN2 1.7215 | PALM 1.7163 | SHISA9 1.7162 | ADORA1 1.7070 | RAPGEF4 1.6971 | CACNG5 1.6745 | EPHA4 1.6721 | ARHGAP32 1.6693 | CAMK2N1 1.6619 | GRM1 1.6533 | NCS1 1.6216 | MIB1 1.6201 | GOPC 1.6059 | LYN 1.5986 | DRD2 1.5853 | SEMA4C 1.5761 | CDK5 1.5715 | FRMPD4 1.5631 | GIPC1 1.5412 | FBXO45 1.5364 | P2RX4 1.5095 | MYH10 1.4980 | SLC8A2 1.4933 | EPS8 1.4871 | DRD1 1.4777 | CABP1 1.4653 | MINK1 1.4611 | LZTS1 1.4506 | DLG3 1.3998 | PICK1 1.3992 | LRRC7 1.3949 | P2RX3 1.3783 | AXIN2 1.3665 | PLCB4 1.3630 | ALS2 1.3539 | GRM3 1.3280 | ADORA2A 1.3027 | KCND2 1.2892 | CACNG8 1.2699 | GRIN1 1.2637 | CHRNA3 1.1921 | KLHL17 1.1909 | HOMER3 1.1653 | GRIA1 1.1475 | MET 1.1441 | PTK2B 1.1280 | SIPA1L1 1.1047 | MYLK2 1.0997 | PALMD 1.0917 | LPHN1 1.0739 | ADRBK1 1.0662 | MTMR2 1.0519 | ADRB2 1.0467 | CHRM1 1.0409 | PJA2 1.0179 | CANX 0.9986 | GRIA2 0.9514 | FBXO2 0.9163 | CDK5R1 0.9094 | CRIPT 0.8965 | LRFN1 0.8886 | OPHN1 0.8605 | DBNL 0.8579 | P2RX6 0.7959 | SHARPIN 0.7933 | P2RY1 0.7649 | LIN7C 0.6405 | STRN4 0.5986 | ATP1A2 0.4943 | MT-ND2 | NLGN4Y | PROSAPIP1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
muscle contraction (boxplot) | 187 | 191 | 4.994107476810829 | 2.955423803463475E-7 | 2.40670011728709E-4 | 0.0 | KCNJ12 5.2371 | ALDOA 4.0025 | KBTBD10 3.9041 | GNAO1 3.7443 | DMD 3.6492 | MAP2K6 3.6149 | SULF2 3.5216 | PSEN2 3.3139 | KCNMA1 3.3055 | MYLK 3.2871 | TCAP 3.2295 | RYR2 3.1737 | TNNC2 3.1678 | ACTN3 3.1352 | ACTA2 3.1316 | TNF 3.0639 | VEGFB 2.9601 | SULF1 2.9550 | PDE4D 2.8834 | ANK2 2.8691 | MYOM2 2.7945 | SLC8A1 2.7718 | UTRN 2.7531 | SMPX 2.6933 | STBD1 2.6787 | KCNQ1 2.5850 | RYR3 2.5711 | ITGA1 2.5638 | CAMK2D 2.5615 | CNN3 2.5363 | MYOM1 2.5153 | TPCN2 2.5016 | TPM3 2.4781 | CACNA1H 2.4410 | TTN 2.4386 | BDKRB2 2.4033 | OXTR 2.3881 | SORBS3 2.3613 | EDN1 2.3459 | NOS1 2.3035 | CHRNB1 2.2963 | MYH11 2.2753 | SCN5A 2.2668 | AGT 2.2659 | CALD1 2.2528 | KCNE2 2.2438 | NKX2-5 2.2385 | COL4A3BP 2.2085 | TRPV1 2.1980 | HOMER1 2.1943 | ADRA1A 2.1619 | TACR2 2.0981 | MYBPC1 2.0903 | NEB 2.0865 | HCN2 2.0858 | ROCK2 2.0790 | ITGB5 2.0784 | TMOD4 2.0639 | ARHGEF11 2.0462 | MYL7 2.0341 | TNNI3 2.0145 | TNNT1 | TNNI2 1.9767 | GAA 1.9633 | MYL6 1.9522 | MYL6B 1.9522 | SNTB1 1.9473 | MYBPC3 1.9461 | CHRM3 1.9459 | ASPH 1.9379 | HTR2B 1.9303 | HRC 1.9153 | PPP1R13L 1.9069 | EDN2 1.8797 | LMOD1 1.8717 | MYL3 1.8709 | DLG1 1.8617 | CKMT2 1.8515 | TNNC1 1.8440 | KCNE1 1.8416 | HSBP1 1.8413 | CACNG1 1.8336 | KCNIP2 1.8243 | KCNH2 1.8168 | MYH6 1.8142 | MYH7 1.8142 | TRDN 1.8131 | ARG2 1.7953 | EDNRB 1.7889 | UTS2 1.7779 | SGCA 1.7693 | TMOD1 1.7664 | CHRND 1.7516 | TNNI1 1.7410 | KNG1 1.7229 | ACTN2 1.7215 | VCL 1.7125 | VIPR1 1.7091 | MYL9 1.7057 | GJA5 1.6874 | TNNT3 1.6778 | SORBS1 1.6523 | DTNA 1.6062 | FLII 1.6028 | TPM1 1.5971 | CASQ2 1.5967 | TSHZ3 1.5963 | MYL12B 1.5886 | DRD2 1.5853 | SCN7A 1.5790 | RCSD1 1.5736 | HCN4 1.5579 | RYR1 1.5561 | MYL2 1.5502 | SSPN 1.5492 | GJA1 1.5265 | MYH2 1.5065 | GALR2 1.4880 | MB 1.4850 | CLCN1 1.4840 | CHRNG 1.4825 | DRD1 1.4777 | CHRNE 1.4611 | LTB4R 1.4548 | GLRA1 1.4443 | MYBPC2 1.4389 | ANKRD2 1.4291 | SMTN 1.4140 | CACNA1S 1.3954 | SLMAP 1.3918 | MYOF 1.3837 | P2RX3 1.3783 | MYL1 1.3574 | TACR1 1.3533 | FXYD1 1.3508 | TBX20 1.3377 | DES 1.3358 | PIK3CA 1.3325 | SCN1B 1.3219 | TPM4 1.3177 | CHRNA1 1.3109 | FKBP1B 1.3101 | MYL4 1.2440 | HTR1D 1.2345 | RPS6KB1 1.2260 | TNNT2 1.2243 | GAL 1.2052 | TPM2 1.1946 | CHRNB4 1.1921 | GDNF 1.1771 | ROCK1 1.1687 | MYH13 1.1562 | MYH4 1.1555 | MYH8 1.1555 | EDN3 1.1118 | CALM2 1.1102 | SSTR2 1.1051 | ACTC1 1.1031 | MYLK2 1.0997 | TAZ 1.0762 | ADRBK1 1.0662 | SCN2B 1.0517 | ADRB2 1.0467 | MYH3 1.0276 | PABPN1 1.0206 | ACTG2 1.0149 | PXN 1.0115 | MYOT 0.9883 | TLR4 0.9855 | ACTA1 0.9736 | TLN1 0.9695 | GJC1 0.9440 | CHRNB2 0.9425 | SMAD5 0.8825 | PIK3C2A 0.8669 | PGAM2 0.8579 | SCN4A 0.8170 | EDNRA 0.8058 | P2RX6 0.7959 | GAMT 0.7763 | NMUR1 0.7701 | IKBKB 0.7521 | EMD 0.7196 | SLC6A8 0.7171 | MAP2K3 0.5826 | SNTA1 0.5644 | VIM 0.5553 | CRYAB 0.5155 | HNTN1 | ID2B | RP5-1049G16.1 | ||||||||||||||||
postsynaptic density (boxplot) | 108 | 111 | 4.909585180699045 | 4.563462461248946E-7 | 3.1852967979517643E-4 | 0.0 | DLGAP1 3.9176 | MAGI2 3.4637 | DNM3 3.4277 | GRIA4 3.3765 | CHRM4 3.3170 | ERBB4 3.2809 | PSD3 3.2638 | DLG2 3.2580 | GRIN3A 3.1467 | SHANK1 3.1256 | DNM2 3.0383 | GRID2 3.0003 | ANKS1B 2.9443 | SYNPO 2.9309 | CACNA1C 2.8754 | SPOCK1 2.7896 | NLGN1 2.7866 | LIN7B 2.7612 | DLGAP3 2.6740 | PDLIM5 2.6326 | NETO1 2.5980 | SRGAP2 2.5232 | DLGAP2 2.4513 | SNAP91 2.4483 | CTNND2 2.4273 | SHANK2 2.3841 | HOMER2 2.3096 | NLGN4X 2.3043 | GRIN2B 2.2951 | CALD1 2.2528 | MAP1B 2.2447 | CPEB1 2.2018 | HOMER1 2.1943 | ARC 2.1147 | CNIH2 2.1101 | GRIN2A 2.0931 | NR3C1 2.0926 | MPDZ 2.0535 | SHANK3 2.0446 | DISC1 2.0102 | LIN7A 2.0092 | DTNBP1 2.0039 | RGS14 1.9785 | GRM5 1.9765 | GRIN2C 1.9757 | AXIN1 1.9756 | SRCIN1 1.9663 | NCOA2 1.9449 | EXOC4 1.9205 | STRN 1.8799 | MAPK8IP2 1.8627 | DLG1 1.8617 | SYNDIG1 1.8308 | YWHAZ 1.7916 | ADAM10 1.7625 | DLG4 1.7370 | TANC1 1.7362 | ADORA1 1.7070 | CACNG5 1.6745 | EPHA4 1.6721 | ARHGAP32 1.6693 | CAMK2N1 1.6619 | GRM1 1.6533 | NCS1 1.6216 | MIB1 1.6201 | GOPC 1.6059 | LYN 1.5986 | DRD2 1.5853 | SEMA4C 1.5761 | CDK5 1.5715 | FBXO45 1.5364 | P2RX4 1.5095 | EPS8 1.4871 | CABP1 1.4653 | MINK1 1.4611 | LZTS1 1.4506 | DLG3 1.3998 | PICK1 1.3992 | LRRC7 1.3949 | AXIN2 1.3665 | PLCB4 1.3630 | ALS2 1.3539 | GRM3 1.3280 | ADORA2A 1.3027 | KCND2 1.2892 | CACNG8 1.2699 | GRIN1 1.2637 | CHRNA3 1.1921 | KLHL17 1.1909 | HOMER3 1.1653 | GRIA1 1.1475 | MET 1.1441 | PTK2B 1.1280 | SIPA1L1 1.1047 | MYLK2 1.0997 | LPHN1 1.0739 | MTMR2 1.0519 | CHRM1 1.0409 | PJA2 1.0179 | GRIA2 0.9514 | CDK5R1 0.9094 | CRIPT 0.8965 | LRFN1 0.8886 | DBNL 0.8579 | P2RX6 0.7959 | SHARPIN 0.7933 | P2RY1 0.7649 | LIN7C 0.6405 | MT-ND2 | NLGN4Y | PROSAPIP1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
dendritic spine head (boxplot) | 108 | 111 | 4.909585180699045 | 4.563462461248946E-7 | 3.1852967979517643E-4 | 0.0 | DLGAP1 3.9176 | MAGI2 3.4637 | DNM3 3.4277 | GRIA4 3.3765 | CHRM4 3.3170 | ERBB4 3.2809 | PSD3 3.2638 | DLG2 3.2580 | GRIN3A 3.1467 | SHANK1 3.1256 | DNM2 3.0383 | GRID2 3.0003 | ANKS1B 2.9443 | SYNPO 2.9309 | CACNA1C 2.8754 | SPOCK1 2.7896 | NLGN1 2.7866 | LIN7B 2.7612 | DLGAP3 2.6740 | PDLIM5 2.6326 | NETO1 2.5980 | SRGAP2 2.5232 | DLGAP2 2.4513 | SNAP91 2.4483 | CTNND2 2.4273 | SHANK2 2.3841 | HOMER2 2.3096 | NLGN4X 2.3043 | GRIN2B 2.2951 | CALD1 2.2528 | MAP1B 2.2447 | CPEB1 2.2018 | HOMER1 2.1943 | ARC 2.1147 | CNIH2 2.1101 | GRIN2A 2.0931 | NR3C1 2.0926 | MPDZ 2.0535 | SHANK3 2.0446 | DISC1 2.0102 | LIN7A 2.0092 | DTNBP1 2.0039 | RGS14 1.9785 | GRM5 1.9765 | GRIN2C 1.9757 | AXIN1 1.9756 | SRCIN1 1.9663 | NCOA2 1.9449 | EXOC4 1.9205 | STRN 1.8799 | MAPK8IP2 1.8627 | DLG1 1.8617 | SYNDIG1 1.8308 | YWHAZ 1.7916 | ADAM10 1.7625 | DLG4 1.7370 | TANC1 1.7362 | ADORA1 1.7070 | CACNG5 1.6745 | EPHA4 1.6721 | ARHGAP32 1.6693 | CAMK2N1 1.6619 | GRM1 1.6533 | NCS1 1.6216 | MIB1 1.6201 | GOPC 1.6059 | LYN 1.5986 | DRD2 1.5853 | SEMA4C 1.5761 | CDK5 1.5715 | FBXO45 1.5364 | P2RX4 1.5095 | EPS8 1.4871 | CABP1 1.4653 | MINK1 1.4611 | LZTS1 1.4506 | DLG3 1.3998 | PICK1 1.3992 | LRRC7 1.3949 | AXIN2 1.3665 | PLCB4 1.3630 | ALS2 1.3539 | GRM3 1.3280 | ADORA2A 1.3027 | KCND2 1.2892 | CACNG8 1.2699 | GRIN1 1.2637 | CHRNA3 1.1921 | KLHL17 1.1909 | HOMER3 1.1653 | GRIA1 1.1475 | MET 1.1441 | PTK2B 1.1280 | SIPA1L1 1.1047 | MYLK2 1.0997 | LPHN1 1.0739 | MTMR2 1.0519 | CHRM1 1.0409 | PJA2 1.0179 | GRIA2 0.9514 | CDK5R1 0.9094 | CRIPT 0.8965 | LRFN1 0.8886 | DBNL 0.8579 | P2RX6 0.7959 | SHARPIN 0.7933 | P2RY1 0.7649 | LIN7C 0.6405 | MT-ND2 | NLGN4Y | PROSAPIP1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ionotropic glutamate receptor activity (boxplot) | 18 | 18 | 4.8008610439245 | 7.899243389397625E-7 | 4.2884114667329776E-4 | 0.0 | GRID1 5.7829 | GRIK4 3.9399 | GRIA4 3.3765 | GRIK2 3.2889 | GRIN3A 3.1467 | GRID2 3.0003 | GRIA3 2.4068 | GRIN2B 2.2951 | GRIN2A 2.0931 | GRIK3 2.0041 | GRIN2C 1.9757 | GRIK1 1.8243 | GRIK5 1.7636 | GRIN2D 1.3766 | GRIN1 1.2637 | GRIA1 1.1475 | GRIN3B 1.0627 | GRIA2 0.9514 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
transmembrane receptor protein tyrosine kinase activity (boxplot) | 66 | 66 | 4.799902262734939 | 7.937154089532328E-7 | 4.2884114667329776E-4 | 0.0 | NTRK3 4.8124 | ROR1 3.4425 | ERBB4 3.2809 | EPHA6 3.2448 | ERBB2 3.2295 | INSR 3.1624 | ROS1 3.0136 | ALK 2.9520 | EGFR 2.8090 | FLT3 2.7949 | NTRK2 2.7766 | FGFR2 2.7650 | EPHA3 2.7107 | EPHB2 2.7088 | EPHB1 2.6334 | FLT1 2.6297 | MUSK 2.5943 | CRIM1 2.5875 | EPHA1 2.5465 | EFEMP1 2.4217 | IGF1R 2.4090 | PDGFRL 2.3802 | EPHA5 2.1737 | LTK 2.0786 | NTRK1 2.0462 | TYRO3 1.9521 | RET 1.9319 | IRS1 1.9115 | TEK 1.8630 | MERTK 1.8314 | EPHA8 1.7658 | EFNA4 1.7569 | INSRR 1.7414 | EPHA7 1.6962 | RYK 1.6892 | PTK7 1.6724 | EPHA4 1.6721 | EPHA10 1.6566 | FGFRL1 1.6492 | PDGFRA 1.6489 | DDR1 1.6458 | TIE1 1.6414 | ROR2 1.6347 | NRP2 1.6343 | NRP1 1.5851 | FGFR1 1.5730 | KDR 1.5543 | TRIM27 1.5287 | IGF2R 1.4885 | FGFR3 1.4587 | EPHB4 1.4218 | AXL 1.4159 | KIT 1.4147 | EFNB3 1.2849 | FLT4 1.2760 | MST1R 1.2550 | CSF1R 1.2307 | PDGFRB 1.2307 | DDR2 1.1922 | EPHA2 1.1715 | MET 1.1441 | FGFR4 1.1354 | EFNA3 1.0625 | ERBB3 1.0409 | EPHB6 0.6660 | EPHB3 0.6149 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
glutamate receptor activity (boxplot) | 26 | 26 | 4.789711122509276 | 8.351079343604795E-7 | 4.2884114667329776E-4 | 0.0 | GRID1 5.7829 | GRIK4 3.9399 | GRIA4 3.3765 | GRIK2 3.2889 | GRM8 3.2143 | GRIN3A 3.1467 | GRID2 3.0003 | GRM7 2.8268 | GRIA3 2.4068 | GRIN2B 2.2951 | GRIN2A 2.0931 | GRIK3 2.0041 | GRM5 1.9765 | GRIN2C 1.9757 | GRIK1 1.8243 | GRM4 1.7819 | GRIK5 1.7636 | GRM1 1.6533 | GRM6 1.5126 | GRIN2D 1.3766 | GRM3 1.3280 | GRIN1 1.2637 | GRIA1 1.1475 | GRM2 1.0960 | GRIN3B 1.0627 | GRIA2 0.9514 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of cholesterol efflux (boxplot) | 11 | 11 | 4.663696069059234 | 1.5528999373071173E-6 | 6.322890911402146E-4 | 0.0 | SIRT1 7.4176 | ABCA1 5.6064 | NFKBIA 2.3376 | PTCH1 2.1082 | ABCG1 2.0741 | LRP1 1.8683 | PON1 1.5922 | APOE 1.4398 | ADIPOQ 1.3289 | NR1H3 1.3265 | NR1H2 1.1632 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
olfactory bulb interneuron differentiation (boxplot) | 12 | 12 | 4.639978072656402 | 1.742230743340123E-6 | 6.548107239969108E-4 | 0.0 | ARX 6.2843 | ERBB4 3.2809 | SLIT1 3.2641 | ROBO2 3.0085 | SLIT2 2.8500 | SLIT3 2.4489 | ROBO1 2.1673 | FGFR1 1.5730 | DICER1 1.4798 | WNT5A 1.3655 | SALL3 1.3649 | SALL1 1.1703 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
protein tyrosine kinase activity (boxplot) | 144 | 151 | 4.62100264099072 | 1.909449566905863E-6 | 6.663978988501462E-4 | 0.0 | NTRK3 4.8124 | BTK 4.4391 | FYN 3.7055 | MAP2K6 3.6149 | ROR1 3.4425 | MAP2K2 3.3627 | ERBB4 3.2809 | EPHA6 3.2448 | ERBB2 3.2295 | JAK1 3.1693 | INSR 3.1624 | FES 3.1088 | MAP2K7 3.0946 | ROS1 3.0136 | ALK 2.9520 | MAP2K5 2.8555 | EGFR 2.8090 | MELK 2.8083 | FLT3 2.7949 | NTRK2 2.7766 | EIF2AK2 2.7737 | FGFR2 2.7650 | EPHA3 2.7107 | EPHB2 2.7088 | TEC 2.6652 | EPHB1 2.6334 | FLT1 2.6297 | MUSK 2.5943 | CRIM1 2.5875 | TXK 2.5595 | EPHA1 2.5465 | NEK10 2.5128 | TTN 2.4386 | EFEMP1 2.4217 | YES1 2.4165 | IGF1R 2.4090 | WEE2 2.3902 | PDGFRL 2.3802 | EPHA5 2.1737 | SYK 2.1149 | FRK 2.0971 | LTK 2.0786 | CLK1 2.0672 | NTRK1 2.0462 | TWF1 1.9582 | TYRO3 1.9521 | RET 1.9319 | OBSCN 1.9276 | IRS1 1.9115 | FER 1.8987 | CAMKK2 1.8746 | JAK3 1.8666 | TEK 1.8630 | AATK 1.8455 | PEAK1 1.8398 | MERTK 1.8314 | MAP2K4 1.8266 | SGK223 1.7934 | EPHA8 1.7658 | CLK4 1.7615 | EFNA4 1.7569 | ABL2 1.7537 | INSRR 1.7414 | MATK 1.7164 | EPHA7 1.6962 | RYK 1.6892 | PTK7 1.6724 | EPHA4 1.6721 | MAP3K9 1.6641 | SRMS 1.6618 | EPHA10 1.6566 | FGFRL1 1.6492 | PDGFRA 1.6489 | DDR1 1.6458 | WEE1 1.6421 | TIE1 1.6414 | ROR2 1.6347 | NRP2 1.6343 | DYRK1A 1.6138 | DSTYK 1.6101 | STK16 1.6097 | LYN 1.5986 | SRC 1.5906 | NRP1 1.5851 | TESK2 1.5784 | MAP3K11 1.5775 | FGFR1 1.5730 | KDR 1.5543 | MAP2K1 1.5376 | TRIM27 1.5287 | TNK2 1.5282 | IGF2R 1.4885 | HCK 1.4790 | FGFR3 1.4587 | RIPK2 1.4586 | ABL1 1.4403 | EPHB4 1.4218 | DYRK4 1.4160 | AXL 1.4159 | KIT 1.4147 | STYK1 1.4111 | JAK2 1.4043 | ZAP70 1.3847 | PTK2 1.3822 | LMTK3 1.3153 | LCK 1.3129 | SHC1 1.2933 | EFNB3 1.2849 | FLT4 1.2760 | BMX 1.2654 | LMTK2 1.2623 | MST1R 1.2550 | CSF1R 1.2307 | PDGFRB 1.2307 | DDR2 1.1922 | FGR 1.1781 | EPHA2 1.1715 | DYRK3 1.1675 | CLK2 1.1605 | PTK6 1.1515 | MET 1.1441 | FGFR4 1.1354 | TTK 1.1348 | PTK2B 1.1280 | DYRK1B 1.1007 | SCYL1 1.0888 | CSK 1.0827 | ITK 1.0826 | BAZ1B 1.0715 | EFNA3 1.0625 | BLK 1.0417 | TYK2 1.0415 | ERBB3 1.0409 | PRKCD 1.0164 | NEK1 0.9135 | TNK1 0.8330 | EPHB6 0.6660 | DYRK2 0.6555 | EPHB3 0.6149 | MAP2K3 0.5826 | TESK1 0.5194 | TP53RK 0.4324 | PLK4 0.4145 | CLK3 0.3891 | BTK kinase deficient isoform 3 | BTK kinase deficient isoform 4 | DKFZp434N1212 | DKFZp686A20267 | MLK4 | MNB | DYRK | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
extracellular matrix part (boxplot) | 184 | 189 | 4.506985016634883 | 3.287763744808103E-6 | 0.0010709342438088262 | 0.0 | EMILIN2 4.7716 | COL11A2 4.6854 | COL10A1 4.5846 | COL15A1 3.8816 | COLEC12 3.2855 | C1QA 3.1690 | C1QB | C1QC | FBLN5 3.1469 | FBLN1 3.1193 | C1QTNF2 3.0733 | VEGFA 3.0488 | TNR 3.0413 | ADAMTS1 2.9721 | COL23A1 2.9611 | TINAG 2.9207 | CCBE1 2.9199 | LAMA3 2.9086 | COL4A2 2.8351 | COLQ 2.7875 | COL13A1 2.7836 | COL6A2 2.7393 | EGFL6 2.6408 | FREM1 2.6344 | COL4A1 2.5872 | FREM2 2.5468 | VWA1 2.5308 | THSD4 2.4632 | THBS2 2.4552 | ACAN 2.4524 | COLEC11 2.4495 | MMRN2 2.4359 | LEPREL1 2.3687 | HMCN1 2.3535 | SPARC 2.3530 | LAMA5 2.3426 | COL19A1 2.3157 | COL25A1 2.3088 | FRAS1 2.2991 | GRIN2B 2.2951 | SCARA3 2.2803 | PRSS12 2.2794 | COL6A5 2.2733 | C1QTNF6 2.2634 | COL4A3 2.2501 | COL27A1 2.2485 | COL12A1 2.2318 | LAMA2 2.2226 | SLC1A3 2.1895 | COL14A1 2.1863 | COL24A1 2.1417 | CST3 2.1381 | TNXB 2.1180 | COL6A1 2.1167 | MARCO 2.1156 | ENTPD2 2.0879 | USH2A 2.0822 | LAMB1 2.0735 | LAMA4 2.0531 | NPNT 2.0460 | NID1 2.0430 | LAMB3 2.0178 | SNCA 1.9846 | SFTPD 1.9782 | FBN1 1.9663 | COL9A1 1.9621 | LAMC1 1.9271 | TNC 1.9083 | COL5A1 1.9082 | FGF9 1.8959 | LOXL2 1.8848 | COL22A1 1.8769 | COL6A3 1.8501 | MFAP4 1.8453 | ERBB2IP 1.8381 | ALB 1.8309 | LAMC2 1.8307 | RUNX1 1.8302 | VWC2 1.8282 | EGFLAM 1.8194 | COLEC10 1.8182 | C1QTNF1 1.8054 | ENTPD1 1.7988 | COL9A3 1.7829 | P4HA3 1.7785 | LUM 1.7679 | FCN1 1.7436 | COL28A1 1.7343 | THBS4 1.7325 | LAMA1 1.7275 | SMOC1 1.7156 | COL8A2 1.7125 | SERPINH1 1.6958 | NTN4 1.6953 | TGFBI 1.6880 | COL6A6 1.6842 | ANG 1.6605 | COL4A4 1.6590 | EDA 1.6572 | MMP2 1.6530 | LAMB4 1.6528 | C1QTNF8 1.6457 | AMTN 1.6104 | C1QTNF5 1.5942 | EMID2 1.5941 | NID2 1.5906 | SMOC2 1.5879 | CCDC80 1.5762 | TIMP3 1.5753 | PLOD1 1.5622 | SMC3 1.5499 | COL21A1 1.5421 | COL16A1 1.5390 | COL8A1 1.5190 | AGRN 1.5051 | FCN3 1.5004 | APLP1 1.4983 | LAMB2 1.4979 | COL1A1 1.4835 | CTHRC1 1.4804 | COL3A1 1.4690 | MMP13 1.4661 | COL17A1 1.4533 | COL5A2 1.4504 | COL11A1 1.4339 | COL7A1 1.4181 | COL1A2 1.4123 | CASK 1.4083 | ANXA2 1.4037 | C1QTNF9 1.3838 | TIMP2 1.3794 | FCN2 1.3678 | COL5A3 1.3492 | COL4A6 1.3398 | DST 1.3319 | COL9A2 1.3311 | ADIPOQ 1.3289 | FREM3 1.3229 | COL2A1 1.3191 | C1QL2 1.3164 | COL4A5 1.3070 | GLDN 1.3027 | HSPG2 1.2964 | RELL2 1.2916 | COL18A1 1.2818 | EMID1 1.2776 | MSR1 1.2705 | LOX 1.2677 | GRIN1 1.2637 | EFEMP2 1.2636 | SPN 1.2252 | TIMP1 1.2251 | LAD1 1.2243 | NTN1 1.2089 | C1QL1 1.1839 | C1QL3 1.1803 | LAMC3 1.1743 | TFF3 1.1530 | SFTPA2 1.1240 | ITGB1 1.1192 | MFAP5 1.1177 | MFAP2 1.1127 | MBL2 1.1098 | WDR33 1.0905 | DCN 1.0126 | C1QTNF9B 0.9871 | FBN2 0.9552 | OTOL1 0.9528 | ACHE 0.9394 | PTPRZ1 0.9164 | MFAP1 0.9119 | ITGB4 0.8918 | COL20A1 0.8836 | ITGA6 0.8763 | EMILIN1 0.8762 | GABRA6 0.8703 | C1QTNF7 0.7801 | PLOD2 0.7720 | AMELX 0.7680 | C1QTNF3 0.7577 | SFTPA1 0.7503 | DAG1 0.6937 | ODAM 0.6718 | ANXA2P2 0.6424 | C1QL4 0.4197 | CILP 0.3044 | AMELY | MAGP2 | MUC5AC | ||||||||||||||||||
triglyceride homeostasis (boxplot) | 19 | 20 | 4.4947056840701345 | 3.4833117974475414E-6 | 0.0010709342438088262 | 0.0 | SIRT1 7.4176 | ANGPTL4 3.7320 | MLXIPL 3.3990 | APOC3 3.0248 | SCARB1 2.6205 | APOA5 2.5911 | ACSM2A 2.2013 | GPIHBP1 2.0087 | LPL 1.9485 | HNF4A 1.7052 | FITM2 1.6446 | CETP 1.6214 | LIPC 1.6053 | GIP 1.4524 | DGAT2 1.4198 | ANGPTL3 1.4147 | APOC2 1.3441 | APOC4 | NR1H3 1.3265 | GCKR 1.2247 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of neuron projection development (boxplot) | 193 | 194 | 4.442382862283179 | 4.448403503332088E-6 | 0.001278523501016505 | 0.0 | DCC 5.1066 | NTRK3 4.8124 | CDH2 3.9744 | PTPRD 3.6941 | KALRN 3.6105 | SLIT1 3.2641 | SCARF1 3.2573 | FKBP4 3.2506 | FES 3.1088 | MBP 3.0687 | RAP2A 3.0635 | TNR 3.0413 | CDH4 3.0350 | ROBO2 3.0085 | LRRC4C 2.9758 | XYLT1 2.9735 | DAB1 2.9720 | CAMK1 2.9695 | NR2E1 2.8955 | SLIT2 2.8500 | TIAM1 2.8400 | SPOCK1 2.7896 | NLGN1 2.7866 | NTRK2 2.7766 | PLXNB2 2.7490 | EPHA3 2.7107 | EPHB2 2.7088 | CCDC88A 2.7048 | ATF1 2.6336 | PMP22 2.6336 | PDLIM5 2.6326 | FIG4 2.6156 | YWHAH 2.6079 | DSCAM 2.5746 | CXCL12 2.5696 | PTPRF 2.5339 | TNIK 2.5237 | CAMK1D 2.4333 | INPPL1 2.4159 | NPTN 2.3588 | MT3 2.3391 | BCL11A 2.3352 | RTN4 2.3237 | TNFRSF12A 2.3109 | CNTN2 2.2820 | NGFR 2.2572 | KNDC1 2.2520 | CAMK2B 2.2519 | MAP1B 2.2447 | RELN 2.2249 | STK25 2.1927 | ROBO1 2.1673 | SPP1 2.1654 | FXN 2.1599 | NUMBL 2.1296 | AKT1 2.1144 | RHOC 2.1005 | WNT3 2.0876 | CDC20 2.0817 | LTK 2.0786 | WNT7A 2.0616 | TWF2 2.0553 | NTRK1 2.0462 | SHANK3 2.0446 | NGF 2.0438 | RUFY3 2.0308 | ISLR2 2.0308 | TRPV4 2.0262 | IL1RAPL1 2.0206 | DISC1 2.0102 | ACTR3 2.0099 | NEDD4 1.9836 | PRKD1 1.9823 | KATNB1 1.9703 | SRCIN1 1.9663 | RET 1.9319 | CACNA1A 1.9305 | RNF6 1.9069 | RHOA 1.8947 | MAG 1.8819 | LPAR1 1.8285 | PLK5 1.8190 | PTPRO 1.7894 | ANAPC2 1.7859 | INPP5J 1.7635 | ABL2 1.7537 | KIAA0319 1.7454 | DPYSL3 1.7243 | UBE2V2 1.7203 | PALM 1.7163 | KIF13B 1.6972 | RAPGEF4 1.6971 | RYK 1.6892 | SEMA3A 1.6808 | PTK7 1.6724 | EPHA4 1.6721 | LRP8 1.6538 | WNT3A 1.6407 | SERPINE2 1.6272 | NCS1 1.6216 | VLDLR 1.6091 | CNR1 1.6061 | MARK2 1.6028 | LYN 1.5986 | BMP7 1.5842 | LRRK2 1.5730 | FGFR1 1.5730 | CDK5 1.5715 | NDEL1 1.5703 | ADNP 1.5371 | NRCAM 1.5362 | NEFM 1.5303 | CAPRIN1 1.5227 | FRMD7 1.5192 | EP300 1.4888 | LIF 1.4805 | CHN1 1.4789 | AMIGO1 1.4658 | LZTS1 1.4506 | APOE 1.4398 | STK24 1.4284 | POU3F2 1.4263 | P2RY2 1.4186 | KLK8 1.4015 | SEMA4D 1.3860 | SMAD1 1.3854 | PTEN 1.3846 | PTK2 1.3822 | PPP2R5B 1.3670 | WNT5A 1.3655 | NDNF 1.3563 | NGEF 1.3111 | DVL1 1.2676 | EFNA1 1.2501 | SEMA3F 1.2271 | FEZ1 1.2217 | SSH1 1.2178 | SEMA4F 1.2167 | NTN1 1.2089 | AVIL 1.2074 | GFAP 1.2059 | CHRNA3 1.1921 | LIMK1 1.1825 | SYNGAP1 1.1743 | STK11 1.1724 | GFI1 1.1568 | ARF6 1.1563 | PTK6 1.1515 | MET 1.1441 | TRPV2 1.1404 | ILK 1.1347 | PTK2B 1.1280 | STMN2 1.1280 | BARHL2 1.1224 | ITGB1 1.1192 | RTN4R 1.1144 | SIPA1L1 1.1047 | SSH3 1.1031 | ITM2C 1.1008 | CAPRIN2 1.0754 | NUMB 1.0524 | INPP5E 1.0413 | HAP1 1.0381 | DBN1 1.0367 | PSEN1 1.0274 | CDKL5 1.0190 | DGUOK 0.9941 | PRKCI 0.9445 | CHRNB2 0.9425 | ACHE 0.9394 | BMP5 0.9345 | ULK1 0.9247 | CDK5R1 0.9094 | LGALS1 0.9091 | HDAC2 0.9044 | KATNA1 0.8990 | ARHGEF1 0.8908 | CNTF 0.8746 | LINGO1 0.8604 | PAFAH1B1 0.8148 | CBFA2T2 0.7972 | SSH2 0.7923 | OMG 0.7849 | SKIL 0.7578 | SEMA7A 0.7223 | TLX2 0.7068 | DIXDC1 0.6947 | PLXNB1 0.6552 | ARHGDIA 0.6161 | EPHB3 0.6149 | THY1 0.6002 | TTL 0.4819 | MAPT 0.4387 | DKFZp434G0625 | |||||||||||||
perikaryon (boxplot) | 41 | 42 | 4.428470876995934 | 4.745176511944393E-6 | 0.0012880518020755725 | 0.0 | GRIK4 3.9399 | CLCN2 3.5399 | GHRH 3.4507 | CNR2 3.3995 | GRIK2 3.2889 | CNTNAP2 3.1556 | ASS1 3.0221 | GNB2L1 3.0025 | PDE11A 2.9328 | SYNPO 2.9309 | KLHL24 2.7317 | PAM 2.6167 | ITGA1 2.5638 | SLC12A5 2.5026 | CTNND2 2.4273 | MAP1B 2.2447 | BTD 2.1546 | AIF1 2.0797 | DDN 2.0180 | GRIK3 2.0041 | TH 1.9742 | MAPK1 1.9571 | CACNA1A 1.9305 | ESR1 1.8508 | TOP1 1.6526 | DRD2 1.5853 | CDK5 1.5715 | CYP11A1 1.5384 | MAP2K1 1.5376 | HTR5A 1.4880 | NDN 1.3688 | NGB 1.2098 | CCR2 1.1711 | CTSL2 1.1085 | CRHBP 1.0855 | EFNA2 0.9726 | GRIA2 0.9514 | CCK 0.9390 | ENO2 0.9115 | TTLL7 0.8979 | NEUROG1 0.6020 | estrogen receptor | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
membrane raft (boxplot) | 189 | 190 | 4.427804098404531 | 4.759865150472109E-6 | 0.0012880518020755725 | 0.0 | ABCA1 5.6064 | DCC 5.1066 | BTK 4.4391 | CDH13 3.9298 | CAV1 3.7656 | PDE2A 3.7330 | EFHD2 3.7201 | DMD 3.6492 | FURIN 3.4013 | PSEN2 3.3139 | KCNMA1 3.3055 | FAS 3.2882 | ERBB4 3.2809 | TNFRSF1B 3.2624 | ERBB2 3.2295 | INSR 3.1624 | CARD11 3.1018 | TNF 3.0639 | TNR 3.0413 | STOML3 2.9765 | SULF1 2.9550 | PODXL 2.9223 | PRNP 2.8953 | LAT 2.8728 | CAV2 2.8160 | EGFR 2.8090 | RAB5A 2.6894 | EPHB1 2.6334 | SCARB1 2.6205 | ADCY5 2.5811 | ITGA1 2.5638 | ADCY2 2.5386 | ADCYAP1R1 2.5080 | BMPR1A 2.4359 | IGF1R 2.4090 | CAV3 2.3881 | HMOX1 2.3654 | DPP4 2.3359 | LAX1 2.2998 | DLC1 2.2963 | SI 2.2951 | PLD2 2.2800 | SLC6A4 2.2725 | HPSE 2.2717 | GRIP1 2.2692 | CXADR 2.1888 | NPHS2 2.1857 | ADCY3 2.1650 | CD28 2.1569 | HK1 2.1198 | PTCH1 2.1082 | WNT3 2.0876 | BSG 2.0858 | LRP6 2.0780 | RIPK1 2.0686 | BMPR2 2.0562 | EFNA5 2.0515 | CD4 2.0421 | WNT1 2.0180 | SPRED1 1.9968 | PTGS2 1.9806 | CBL 1.9784 | FLOT2 1.9629 | GABBR1 1.9622 | MAPK1 1.9571 | FAIM2 1.9527 | P2RX1 1.9501 | OPRD1 1.9420 | CTSB 1.9372 | IRS1 1.9115 | PAG1 1.9087 | STX2 1.8832 | RFTN1 1.8745 | TEK 1.8630 | MAPK3 1.8628 | DLG1 1.8617 | P2RX7 1.8574 | GJA3 1.8344 | SMO 1.8103 | TDGF1 1.8065 | FASLG 1.8023 | PTRF 1.7946 | PPT1 1.7921 | PLLP 1.7913 | PRKAR2B 1.7791 | SGCA 1.7693 | MLC1 1.7589 | CBLB 1.7575 | ARID3A 1.7173 | GHSR 1.7166 | PLVAP 1.6992 | CD14 1.6905 | LRP8 1.6538 | SORBS1 1.6523 | WNT3A 1.6407 | GNAI1 1.6302 | NOS3 1.6288 | TRPC4 1.6274 | PI4K2A 1.5996 | LYN 1.5986 | TGFBR2 1.5967 | SRC 1.5906 | LRRK2 1.5730 | SMPD2 1.5327 | GJA1 1.5265 | RTN4RL1 1.5091 | ADAM17 1.5056 | NPHS1 1.4983 | CD48 1.4980 | GPC1 1.4900 | HCK 1.4790 | DRD1 1.4777 | ARID3C 1.4745 | CD36 1.4667 | SNAP25 1.4539 | GNAI3 1.4435 | F2R 1.4291 | MS4A2 1.4184 | PTPRC 1.4182 | JAK2 1.4043 | FADD 1.3890 | MYOF 1.3837 | P2RX3 1.3783 | LAT2 1.3653 | GPM6B 1.3610 | LAMTOR1 1.3465 | MAL 1.3433 | KIF18A 1.3361 | SLC27A1 1.3359 | LCK 1.3129 | CLN3 1.3063 | ATP1B3 1.2935 | SDC4 1.2900 | TEX101 1.2650 | SHH 1.2438 | FLOT1 1.2304 | SLC9A1 1.1993 | UMOD 1.1937 | LIPE 1.1888 | CASP8 1.1822 | SELE 1.1773 | PIKFYVE 1.1741 | TNFRSF1A 1.1656 | RHOQ 1.1486 | ANGPT1 1.1416 | PTK2B 1.1280 | CD226 1.1277 | ITGB1 1.1192 | SLC2A1 1.1124 | TSC2 1.0731 | ADRBK1 1.0662 | ACE2 1.0503 | ADRB2 1.0467 | TRAF2 1.0448 | SLC22A6 1.0441 | PSEN1 1.0274 | SDPR 1.0254 | ATP1B1 1.0200 | KRAS 0.9975 | CLIP3 0.9895 | TLR4 0.9855 | PLSCR1 0.9775 | EFNB1 0.9761 | CD55 0.9660 | TRPC1 0.9629 | NPC1 0.9459 | RTN4RL2 0.9400 | CD79A 0.8908 | LAMTOR2 0.8797 | RGS16 0.8763 | LAMTOR3 0.8566 | PTGIS 0.8316 | BCL10 0.8189 | ITLN1 0.8094 | EDNRA 0.8058 | NFAM1 0.7992 | ADCY6 0.7536 | IKBKB 0.7521 | RGMB 0.7395 | STOM 0.7036 | DAG1 0.6937 | STX12 0.6580 | MALL 0.6023 | THY1 0.6002 | GNAI2 0.5640 | SMURF2 0.5435 | ATP1A2 0.4943 | HYAL2 0.2244 | HDAC6 0.1384 | CD24 | |||||||||||||||||
regulation of membrane potential (boxplot) | 185 | 187 | 4.400509974826349 | 5.399838136188606E-6 | 0.0013191804566708766 | 0.0 | MPP5 5.2324 | SCN3B 4.2468 | ARHGEF10 3.8915 | CAV1 3.7656 | SCN2A 3.6519 | NRXN1 3.6097 | CNR2 3.3995 | KCNMA1 3.3055 | GRIK2 3.2889 | ERBB2 3.2295 | CACNB4 3.1376 | SHANK1 3.1256 | MBP 3.0687 | HEXA 3.0328 | BAX 3.0299 | CACNA1G 3.0242 | GRID2 3.0003 | PID1 2.9916 | NFASC 2.9513 | ASPA 2.8861 | KCNIP1 2.8571 | NLGN1 2.7866 | ASIC2 2.7474 | KCNMB2 2.6357 | JAM3 2.6353 | PMP22 2.6336 | PEX5L 2.5959 | KCNQ1 2.5850 | SCN9A 2.5308 | NAB1 2.5233 | SLC1A6 2.4978 | PRDX3 2.4689 | SBF2 2.4546 | KCNMB3 2.4149 | CAV3 2.3881 | EDN1 2.3459 | HEXB 2.3391 | NLGN4X 2.3043 | CHRNB1 2.2963 | GRIN2B 2.2951 | CNTN2 2.2820 | SCN5A 2.2668 | CACNG4 2.2546 | RELN 2.2249 | AIFM3 2.2178 | SKI 2.1799 | BCL2 2.1766 | ADRA1A 2.1619 | SCN8A 2.1612 | ACSBG1 2.1597 | CNIH2 2.1101 | NDRG1 2.0974 | CACNA1E 2.0970 | GRIN2A 2.0931 | PARK7 2.0872 | HCN2 2.0858 | ATXN1 2.0856 | QKI 2.0538 | ERCC2 2.0521 | XIRP1 2.0504 | SHANK3 2.0446 | PRX 2.0418 | HTT 2.0106 | GRIK3 2.0041 | SNCA 1.9846 | GRIN2C 1.9757 | P2RX1 1.9501 | KCNMB4 1.9400 | CACNA1A 1.9305 | ABCB5 1.9190 | EGR2 1.8938 | JUN 1.8868 | CX3CL1 1.8760 | AFG3L2 1.8657 | MAPK8IP2 1.8627 | P2RX7 1.8574 | CACNA1B 1.8481 | KCNE1 1.8416 | DRD4 1.8319 | LPAR1 1.8285 | GRIK1 1.8243 | KCNH2 1.8168 | NKX6-2 1.8055 | PRKCZ 1.7929 | PLLP 1.7913 | SLC17A7 1.7655 | GNAQ 1.7558 | PMAIP1 1.7492 | EIF2B4 1.7419 | DLG4 1.7370 | ADAM22 1.7197 | ADORA1 1.7070 | BAD 1.6791 | PIAS3 1.6400 | TAC1 1.6069 | CNR1 1.6061 | ADRB1 1.6047 | BEST2 1.6024 | NLGN3 1.5936 | NAB2 1.5795 | LRRK2 1.5730 | CDK5 1.5715 | PPARD 1.5657 | MYO5A 1.5529 | GJD2 1.5523 | NTSR2 1.5195 | KCNN4 1.5095 | P2RX4 1.5095 | CD9 1.5036 | GPC1 1.4900 | DICER1 1.4798 | DRD1 1.4777 | GIMAP5 1.4739 | SMAD7 1.4674 | AMIGO1 1.4658 | HES5 1.4456 | GLRA1 1.4443 | POU3F2 1.4263 | PPP3CA 1.4235 | PLP1 1.4162 | PTEN 1.3846 | P2RX3 1.3783 | CACNG2 1.3692 | TACR1 1.3533 | LGI4 1.3508 | MAL 1.3433 | GNA11 1.3379 | TSC1 1.3322 | ADIPOQ 1.3289 | SCN1B 1.3219 | SLC29A1 1.3140 | CHRNA1 1.3109 | CLN3 1.3063 | ADORA2A 1.3027 | NF1 1.2913 | KCND2 1.2892 | DLD 1.2839 | EIF2B5 1.2665 | CNTNAP1 1.2662 | GRIN1 1.2637 | CXCR4 1.2607 | KLK6 1.2520 | GNPAT 1.2058 | CHRNA4 1.2001 | CHRNA3 1.1921 | CHRNB4 | GLRB 1.1896 | GAL3ST1 1.1795 | KCNJ11 1.1557 | SLC26A5 1.1553 | ILK 1.1347 | SOD2 1.1214 | ID4 1.1089 | SLC9A3R2 1.0731 | MTMR2 1.0519 | SCN2B 1.0517 | ADRB2 1.0467 | PSEN1 1.0274 | DHH 0.9994 | GHRL 0.9974 | NTF3 0.9832 | TGFB1 0.9693 | POU3F1 0.9537 | CHRNB2 0.9425 | BNIP3 0.9338 | NDUFS1 0.9332 | DMPK 0.8803 | SRI 0.8747 | CNTF 0.8746 | SOD1 0.8543 | KCNJ10 0.8338 | UGT8 0.8186 | OLIG2 0.8085 | FOXA2 0.8073 | BCL2L1 0.8053 | RANGRF 0.7954 | BAK1 0.7850 | CACNB3 0.7536 | ZNF24 0.7153 | GJC3 0.7123 | DAG1 0.6937 | NLGN2 0.6604 | CLDN11 0.6198 | HCRT 0.5645 | CHRNA6 0.3958 | EIF2B2 0.2862 | MRF | ||||||||||||||||||||
muscle cell development (boxplot) | 98 | 100 | 4.389037449859584 | 5.692673194945819E-6 | 0.001324495296690727 | 0.0 | GPHN 5.9364 | HES1 3.7965 | MYPN 3.2513 | ERBB2 3.2295 | TCAP | VEGFA 3.0488 | ANKRD1 2.9349 | PROX1 2.8868 | CAV2 2.8160 | NEBL 2.7784 | SLC8A1 2.7718 | CHAT 2.7603 | FHL2 2.6776 | TBX3 2.6289 | MUSK 2.5943 | SGCZ 2.5939 | KDM1A 2.5909 | COL4A1 2.5872 | TTN 2.4386 | CAV3 2.3881 | FOXP1 2.3270 | CHRNB1 2.2963 | NFATC4 2.2770 | MYH11 2.2753 | AGT 2.2659 | NKX2-5 2.2385 | MYO18B 2.2179 | CACNB2 2.2123 | HOMER1 2.1943 | CXADR 2.1888 | SKI 2.1799 | DNER 2.1720 | LRP4 2.1606 | ACTB 2.1337 | APP 2.1303 | MYOZ1 2.0827 | PDZRN3 2.0541 | XIRP1 2.0504 | MEF2C 2.0426 | WNT10B 2.0180 | AXIN1 1.9756 | MYBPC3 1.9461 | TNC 1.9083 | ACTG1 1.9056 | NFATC3 1.9050 | GPX1 1.8947 | MEGF10 1.8707 | AFG3L2 1.8657 | RCAN1 1.8416 | MYH6 1.8142 | TMOD1 1.7664 | ADM 1.7485 | LEF1 1.7470 | MYLK3 1.7219 | PDGFRA 1.6489 | NKX2-6 1.6263 | TPM1 1.5971 | MYOG 1.5902 | CAPN3 1.5788 | LRRK2 1.5730 | KRT19 1.5729 | NEURL2 1.5580 | RYR1 1.5561 | MYL2 1.5502 | KIAA1161 1.5218 | MYH10 1.4980 | LAMB2 1.4979 | MEF2A 1.4880 | DICER1 1.4798 | F2R 1.4291 | PPP3CA 1.4235 | DNAJA3 1.4206 | CACNA1S 1.3954 | CACNG2 1.3692 | ALS2 1.3539 | ATG5 1.3205 | CHRNA1 1.3109 | COL4A5 1.3070 | MYOD1 1.2690 | DVL1 1.2676 | CDK1 1.2389 | PDGFRB 1.2307 | TNNT2 1.2243 | DOK7 1.2147 | SRF 1.1778 | OBSL1 1.1569 | BMP10 1.1425 | ATG7 1.1390 | ITGB1 1.1192 | ACTC1 1.1031 | LMNA 1.0722 | SDC1 1.0557 | NRD1 1.0284 | ACTA1 0.9736 | RAMP2 0.9523 | PTCD2 0.9115 | HEY2 0.8433 | SNTA1 0.5644 | CCNB1 0.5640 | HNTN1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of cholesterol transport (boxplot) | 12 | 12 | 4.369639939984694 | 6.2225783292735315E-6 | 0.0013819780780377489 | 0.0 | SIRT1 7.4176 | ABCA1 5.6064 | NFKBIA 2.3376 | PTCH1 2.1082 | ABCG1 2.0741 | LRP1 1.8683 | PON1 1.5922 | APOE 1.4398 | ADIPOQ 1.3289 | NR1H3 1.3265 | LIPG 1.3223 | NR1H2 1.1632 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of sterol transport (boxplot) | 12 | 12 | 4.369639939984694 | 6.2225783292735315E-6 | 0.0013819780780377489 | 0.0 | SIRT1 7.4176 | ABCA1 5.6064 | NFKBIA 2.3376 | PTCH1 2.1082 | ABCG1 2.0741 | LRP1 1.8683 | PON1 1.5922 | APOE 1.4398 | ADIPOQ 1.3289 | NR1H3 1.3265 | LIPG 1.3223 | NR1H2 1.1632 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of synaptic transmission (boxplot) | 176 | 177 | 4.3526200184061405 | 6.726009335045191E-6 | 0.0013819780780377489 | 0.0 | CNTN4 4.2048 | NRXN1 3.6097 | CNR2 3.3995 | GRIA4 3.3765 | PARK2 3.3357 | PSEN2 3.3139 | GRIK2 3.2889 | ERBB4 3.2809 | CPLX2 3.2544 | GRM8 3.2143 | TNF 3.0639 | TNR 3.0413 | RASGRF1 2.9288 | NR2E1 2.8955 | KCNQ4 2.8155 | NLGN1 2.7866 | MMP9 2.7841 | PPFIA3 2.7612 | CHAT 2.7603 | PRKCE 2.7354 | EPHB2 2.7088 | STX1A 2.7012 | HRAS 2.6539 | STXBP1 2.6367 | YWHAH 2.6079 | NETO1 2.5980 | GRID2IP 2.4971 | PLK2 2.4876 | SNCG 2.4359 | CTNND2 2.4273 | PPP3CB 2.4174 | VGF 2.3948 | OXTR 2.3881 | KCNC4 2.3714 | HTR1B 2.3684 | NPTN 2.3588 | EDN1 2.3459 | NOS1 2.3035 | GRIN2B 2.2951 | CNTN2 2.2820 | SLC6A4 2.2725 | AGT 2.2659 | CAMK2B 2.2519 | MAP1B 2.2447 | RELN 2.2249 | LAMA2 2.2226 | CPEB1 2.2018 | SLC1A3 2.1895 | JPH3 2.1788 | ADRA1A 2.1619 | CAMK2A 2.1496 | SNCAIP 2.1411 | ARC 2.1147 | GRIN2A 2.0931 | CDC20 2.0817 | SHANK3 2.0446 | NGF 2.0438 | MEF2C 2.0426 | SLC30A1 2.0329 | HTT 2.0106 | ATAD1 2.0096 | GRIK3 2.0041 | SNCA 1.9846 | PTGS2 1.9806 | RGS14 1.9785 | GRM5 1.9765 | GABBR1 1.9622 | DRD3 1.9435 | KCNMB4 1.9400 | RIMS1 1.9395 | CACNA1A 1.9305 | SLC24A2 1.9291 | OXT 1.9195 | EGR2 1.8938 | UNC13B 1.8915 | NISCH 1.8699 | MAPK8IP2 1.8627 | CD38 1.8553 | NCDN 1.8469 | DRD4 1.8319 | GRIK1 1.8243 | NEUROD2 1.8013 | PRKCZ 1.7929 | ANAPC2 1.7859 | DLG4 1.7370 | KISS1R 1.7173 | SHISA9 1.7162 | PFN2 1.7072 | ADORA1 1.7070 | RAPGEF4 1.6971 | UNC13A 1.6800 | LRP8 1.6538 | GRM1 1.6533 | CSPG5 1.6448 | GNAI1 1.6302 | SERPINE2 1.6272 | RAPGEF2 1.6242 | TAC1 1.6069 | CNR1 1.6061 | NLGN3 1.5936 | DRD2 1.5853 | HTR2A 1.5850 | NPY5R 1.5788 | CDK5 1.5715 | GIPC1 1.5412 | ADNP 1.5371 | CPLX4 1.5355 | ABHD6 1.5138 | ARRB2 1.4934 | NAPA 1.4933 | DRD1 1.4777 | MGLL 1.4752 | SLC6A1 1.4647 | GIP 1.4524 | GNAI3 1.4435 | LGI1 1.4430 | APOE 1.4398 | RAB3A 1.4334 | PPP3CA 1.4235 | CALB1 1.4175 | SYNGR1 1.4155 | PTEN 1.3846 | P2RX3 1.3783 | GPM6B 1.3610 | BHLHE40 1.3567 | CRHR1 1.3545 | TACR1 1.3533 | CCKBR 1.3511 | ADIPOQ 1.3289 | GRM3 1.3280 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | BDNF 1.2240 | RAB11A 1.2181 | BCAN 1.2096 | GFAP 1.2059 | CHRNA3 1.1921 | CHRNB4 | PINK1 1.1846 | SRF 1.1778 | GDNF 1.1771 | SYNGAP1 1.1743 | SLC18A1 1.1645 | BCHE 1.1249 | PMCH 1.1212 | NAPB 1.1192 | YWHAG 1.1107 | CPLX3 1.1056 | SIPA1L1 1.1047 | MYLK2 1.0997 | PXK 1.0895 | PLAT 1.0689 | DBN1 1.0367 | PSEN1 1.0274 | KRAS 0.9975 | S100B 0.9943 | NTF3 0.9832 | CHRNB2 0.9425 | ACHE 0.9394 | NRAS 0.9279 | PEBP1 0.9211 | NMU 0.8991 | IFNG 0.8931 | OPHN1 0.8605 | SYP 0.8425 | KCNJ10 0.8338 | UCN 0.8158 | KCNC3 0.8056 | PRKACA 0.6979 | CCL2 0.6763 | NLGN2 0.6604 | HCRT 0.5645 | GNAI2 0.5640 | EGR1 0.5440 | PATE4 0.5341 | USP46 0.2843 | ||||||||||||||||||||||||||||||
extracellular-glutamate-gated ion channel activity (boxplot) | 19 | 19 | 4.34854738439346 | 6.852110579491644E-6 | 0.0013819780780377489 | 0.0 | GRID1 5.7829 | GRIK4 3.9399 | GRIA4 3.3765 | GRIK2 3.2889 | GRIN3A 3.1467 | GRID2 3.0003 | GRIA3 2.4068 | GRIN2B 2.2951 | GRIN2A 2.0931 | GRIK3 2.0041 | GRIN2C 1.9757 | GRIK1 1.8243 | GRIK5 1.7636 | GRIN2D 1.3766 | GRIN1 1.2637 | GRIA1 1.1475 | GRIN3B 1.0627 | GRIA2 0.9514 | STX1B 0.5451 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
white fat cell differentiation (boxplot) | 12 | 12 | 4.321681074843445 | 7.742244971575829E-6 | 0.0014549464973507501 | 0.0 | SIRT1 7.4176 | PRDM16 3.9381 | AACS 3.2912 | SNAI2 2.6919 | CTBP2 2.3713 | NCOR2 2.2598 | CTBP1 1.9311 | PPARG 1.6692 | CEBPA 1.3881 | FABP4 1.3200 | FGF10 0.7055 | ADIG 0.4821 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of transmission of nerve impulse (boxplot) | 189 | 192 | 4.290763262269055 | 8.903002880478184E-6 | 0.001611113780519126 | 0.0 | CNTN4 4.2048 | CDH2 3.9744 | NRXN1 3.6097 | CNR2 3.3995 | GRIA4 3.3765 | PARK2 3.3357 | PSEN2 3.3139 | GRIK2 3.2889 | ERBB4 3.2809 | CPLX2 3.2544 | GRM8 3.2143 | TNF 3.0639 | TNR 3.0413 | RASGRF1 2.9288 | NR2E1 2.8955 | KCNQ4 2.8155 | NLGN1 2.7866 | MMP9 2.7841 | PPFIA3 2.7612 | CHAT 2.7603 | PRKCE 2.7354 | EPHB2 2.7088 | STX1A 2.7012 | HRAS 2.6539 | STXBP1 2.6367 | YWHAH 2.6079 | NETO1 2.5980 | GRID2IP 2.4971 | PLK2 2.4876 | SNCG 2.4359 | CTNND2 2.4273 | PPP3CB 2.4174 | VGF 2.3948 | OXTR 2.3881 | KCNC4 2.3714 | HTR1B 2.3684 | NPTN 2.3588 | EDN1 2.3459 | NOS1 2.3035 | GRIN2B 2.2951 | RNF10 2.2852 | CNTN2 2.2820 | SLC6A4 2.2725 | AGT 2.2659 | CAMK2B 2.2519 | MAP1B 2.2447 | RELN 2.2249 | LAMA2 2.2226 | CPEB1 2.2018 | SLC1A3 2.1895 | JPH3 2.1788 | ADRA1A 2.1619 | CAMK2A 2.1496 | SNCAIP 2.1411 | ARC 2.1147 | GRIN2A 2.0931 | TCF7L2 2.0892 | CDC20 2.0817 | SHANK3 2.0446 | NGF 2.0438 | MEF2C 2.0426 | SLC30A1 2.0329 | HTT 2.0106 | ATAD1 2.0096 | GRIK3 2.0041 | SNCA 1.9846 | PTGS2 1.9806 | RGS14 1.9785 | GRM5 1.9765 | GABBR1 1.9622 | DRD3 1.9435 | KCNMB4 1.9400 | RIMS1 1.9395 | CACNA1A 1.9305 | SLC24A2 1.9291 | AVP 1.9195 | OXT | EGR2 1.8938 | UNC13B 1.8915 | NISCH 1.8699 | MAPK8IP2 1.8627 | CD38 1.8553 | NCDN 1.8469 | TG 1.8438 | DRD4 1.8319 | GRIK1 1.8243 | NEUROD2 1.8013 | PRKCZ 1.7929 | ANAPC2 1.7859 | DLG4 1.7370 | KISS1R 1.7173 | SHISA9 1.7162 | IL6 1.7153 | PFN2 1.7072 | ADORA1 1.7070 | RAPGEF4 1.6971 | UNC13A 1.6800 | LRP8 1.6538 | GRM1 1.6533 | CSPG5 1.6448 | GNAI1 1.6302 | SERPINE2 1.6272 | RAPGEF2 1.6242 | TAC1 1.6069 | CNR1 1.6061 | NLGN3 1.5936 | DRD2 1.5853 | HTR2A 1.5850 | NPY5R 1.5788 | CDK5 1.5715 | GIPC1 1.5412 | ADNP 1.5371 | CPLX4 1.5355 | ABHD6 1.5138 | ARRB2 1.4934 | NAPA 1.4933 | CARTPT 1.4844 | DICER1 1.4798 | DRD1 1.4777 | MGLL 1.4752 | SLC6A1 1.4647 | GIP 1.4524 | HES5 1.4456 | GLRA1 1.4443 | GNAI3 1.4435 | LGI1 1.4430 | APOE 1.4398 | RAB3A 1.4334 | PPP3CA 1.4235 | CALB1 1.4175 | SYNGR1 1.4155 | KLK8 1.4015 | PTEN 1.3846 | P2RX3 1.3783 | GPM6B 1.3610 | BHLHE40 1.3567 | CRHR1 1.3545 | TACR1 1.3533 | CCKBR 1.3511 | ADIPOQ 1.3289 | GRM3 1.3280 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | BDNF 1.2240 | RAB11A 1.2181 | BCAN 1.2096 | GFAP 1.2059 | CHRNA3 1.1921 | CHRNB4 | PINK1 1.1846 | SRF 1.1778 | GDNF 1.1771 | SYNGAP1 1.1743 | SLC18A1 1.1645 | BCHE 1.1249 | PMCH 1.1212 | NAPB 1.1192 | YWHAG 1.1107 | CPLX3 1.1056 | SIPA1L1 1.1047 | MYLK2 1.0997 | PXK 1.0895 | PLAT 1.0689 | DBN1 1.0367 | PSEN1 1.0274 | KRAS 0.9975 | S100B 0.9943 | NTF3 0.9832 | CHRNB2 0.9425 | ACHE 0.9394 | NRAS 0.9279 | PEBP1 0.9211 | NMU 0.8991 | IFNG 0.8931 | OPHN1 0.8605 | SYP 0.8425 | KCNJ10 0.8338 | UCN 0.8158 | KCNC3 0.8056 | EIF2AK3 0.7800 | PRKACA 0.6979 | AVPR1A 0.6808 | CCL2 0.6763 | NLGN2 0.6604 | HCRT 0.5645 | GNAI2 0.5640 | CTNNB1 0.5466 | EGR1 0.5440 | PATE4 0.5341 | USP46 0.2843 | MRF | |||||||||||||||
regulation of Rho protein signal transduction (boxplot) | 157 | 161 | 4.2696779270409735 | 9.787771766411879E-6 | 0.001707966173238873 | 0.0 | CRK 4.9972 | CDH2 3.9744 | ARHGEF10 3.8915 | ARAP1 3.7330 | CCL24 3.7243 | SPATA13 3.6908 | KALRN 3.6105 | PLEKHG2 3.4715 | PLEKHG1 3.2405 | ERBB2 3.2295 | PREX1 2.9502 | PKP4 2.9360 | RASGRF1 2.9288 | ARHGAP15 2.9085 | ARHGEF3 2.8881 | AKAP13 2.8539 | TIAM1 2.8400 | GMIP 2.8343 | LPAR2 | NTRK2 2.7766 | PLXNB2 2.7490 | EPHA3 2.7107 | RGNEF 2.6947 | FZD10 2.6723 | EPHA1 2.5465 | ARHGAP26 2.5226 | MCF2 2.4868 | RHOG 2.4848 | CD40 2.4680 | RASGRF2 2.4633 | TIAM2 2.4489 | FGD2 2.4194 | DOCK4 2.3990 | MYO9B 2.3989 | ARAP3 2.3645 | CUL3 2.3518 | TAX1BP3 2.3388 | CCR7 2.3166 | DLC1 2.2963 | FARP1 2.2734 | FARP2 2.2728 | MCF2L2 2.2166 | ARHGEF18 2.2107 | ARHGEF38 2.2024 | PREX2 2.2018 | ARHGAP6 2.1854 | EPHA5 2.1737 | ADRA1A 2.1619 | ITSN2 2.1500 | TRIO 2.1284 | CCL26 2.1094 | ARHGEF9 2.0887 | KCTD13 2.0841 | PIP5K1A 2.0835 | FGD4 2.0673 | ARHGEF5 2.0614 | EFNA5 2.0515 | ARHGEF11 2.0462 | ITSN1 2.0433 | FGD5 1.9928 | VAV2 1.9727 | PLEKHG7 1.9482 | OBSCN 1.9276 | RAC1 1.9125 | SCRIB 1.9095 | JUN 1.8868 | BCL6 1.8618 | VAV3 1.8406 | LPAR1 1.8285 | ARHGAP5 1.8010 | ABR 1.7595 | MTOR 1.7516 | STMN3 1.7349 | RAF1 1.7090 | EPHA4 1.6721 | TNFAIP1 1.6556 | ALS2CL 1.6454 | ARHGEF4 1.6452 | ARHGEF37 1.6201 | F2RL1 1.6183 | ARRB1 1.5906 | ARHGAP35 1.5865 | PLEKHG5 1.5723 | NDEL1 1.5703 | ARHGEF16 1.5691 | PLEKHG6 1.5603 | MCF2L 1.5518 | FGD6 1.5470 | ECT2L 1.5269 | RALBP1 1.5236 | SOS2 1.5227 | ERRFI1 1.5159 | AGRN 1.5051 | DYNLT1 1.4972 | CHN1 1.4789 | FGD3 1.4630 | ARHGAP1 1.4596 | NET1 1.4291 | F2R 1.4291 | DOCK7 1.4147 | ARHGEF26 1.4139 | ARHGEF10L 1.4113 | FGD1 1.4085 | ARHGEF40 1.3953 | VAV1 1.3902 | BCR 1.3878 | SEMA4D 1.3860 | ARHGAP8 1.3860 | PTK2 1.3822 | ALS2 1.3539 | CDC42EP2 1.3369 | TSC1 1.3322 | NGEF 1.3111 | CCL11 1.3027 | ARHGEF15 1.2884 | ARHGEF12 1.2882 | SFRP1 1.2842 | CCL19 1.2605 | CCL21 | NCKAP1L 1.2593 | FOXJ1 1.2168 | SYDE1 1.1983 | GSK3B 1.1968 | C9orf100 1.1946 | EPHA2 1.1715 | DNMBP 1.1537 | SOS1 1.1496 | ARHGEF25 1.1372 | PTK2B 1.1280 | ARHGEF7 1.1278 | ARHGEF33 1.0894 | ARHGEF2 1.0873 | PLEKHG4B 1.0721 | RASIP1 1.0401 | CDKL5 1.0190 | ARHGAP27 0.9711 | GPR55 0.9634 | FICD 0.9592 | BVES 0.9470 | ARHGEF19 0.9428 | ARHGAP29 0.9245 | ABRA 0.9240 | ARHGEF17 0.9078 | SCAI 0.9077 | ARHGEF1 0.8908 | GPR65 0.8893 | PLEKHG3 0.8754 | OPHN1 0.8605 | GRHL3 0.8241 | PAFAH1B1 0.8148 | ARHGAP4 0.7810 | SYDE2 0.6997 | PIN1 0.6765 | PLXNB1 0.6552 | ARHGEF6 0.6228 | EPHB3 0.6149 | THY1 0.6002 | ECT2 0.5904 | PLEKHG4 0.4639 | FRAP1 | RP11-114F7.3 | ||||||||||||||||||||||||||||||||||||||||||||||
regulation of cellular senescence (boxplot) | 10 | 10 | 4.240240724535082 | 1.116401027667635E-5 | 0.0018809432486841602 | 0.0 | SIRT1 7.4176 | CDKN2A 3.0353 | ING2 2.8259 | HMGA2 2.5708 | TWIST1 2.0979 | PNPT1 2.0485 | CDK6 2.0335 | NUAK1 1.1328 | HMGA1 1.0845 | NEK6 0.9782 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
synaptosome (boxplot) | 116 | 118 | 4.1993990437983895 | 1.3381215956176362E-5 | 0.002179354038729257 | 0.0 | SEPT7 4.3221 | VAMP1 4.1635 | GNAO1 3.7443 | MAGI2 3.4637 | CNR2 3.3995 | ERC2 3.3555 | SHANK1 3.1256 | GRID2 3.0003 | RASGRF1 2.9288 | LIN7B 2.7612 | CHAT 2.7603 | VAMP3 2.7537 | ASIC2 2.7474 | STX1A 2.7012 | SNPH 2.6851 | DLGAP3 2.6740 | PDLIM5 2.6326 | GRID2IP 2.4971 | FZD1 2.4363 | CTNND2 2.4273 | ATP6V0D1 2.4205 | SHANK2 2.3841 | SYNPR 2.3480 | GRIN2B 2.2951 | SEPT2 2.2728 | SLC6A4 2.2725 | SEPT5 2.2712 | GRIP1 2.2692 | CADM1 2.2215 | HOMER1 2.1943 | SV2A 2.1873 | CYFIP2 2.1614 | SNAP29 2.1597 | ABI1 2.1356 | APP 2.1303 | GRIN2A 2.0931 | NR3C1 2.0926 | MPDZ 2.0535 | PPP1R9A 2.0454 | SHANK3 2.0446 | ITSN1 2.0433 | PPFIA2 2.0377 | MYO5B 2.0328 | SLC17A8 2.0171 | LIN7A 2.0092 | DTNBP1 2.0039 | SNCA 1.9846 | TH 1.9742 | GABBR1 1.9622 | BRAF 1.9582 | PRKCG 1.9540 | CYFIP1 1.9503 | P2RX1 1.9501 | SNCB 1.9380 | SLC17A6 1.8970 | P2RX7 1.8574 | PIK3R1 1.8351 | SEPT3 1.7964 | SLC17A7 1.7655 | RNPEP 1.7492 | DLG4 1.7370 | BAG3 1.7304 | RPH3A 1.6628 | CAMK2N1 1.6619 | DPYSL2 1.6469 | SAMD4A 1.6370 | GOPC 1.6059 | PVRL1 1.5566 | SH3KBP1 1.5425 | DOC2A 1.5395 | FOS 1.5019 | LAMB2 1.4979 | RNF40 1.4903 | EPS8 1.4871 | SDC3 1.4674 | SLC6A1 1.4647 | SNAP25 1.4539 | RAB3A 1.4334 | PICK1 1.3992 | PTEN 1.3846 | ABAT 1.3792 | P2RX3 1.3783 | PSPH 1.3768 | GRIN2D 1.3766 | LGI3 1.3710 | ALS2 1.3539 | SNAPIN 1.3340 | ITGA3 1.3270 | ACP2 1.3265 | KCND2 1.2892 | DVL1 1.2676 | GRIN1 1.2637 | RPS6KB1 1.2260 | SEMA4F 1.2167 | HNMT 1.2017 | SLC6A3 1.1970 | CHRNB4 1.1921 | FOSL1 1.1638 | GRIA1 1.1475 | ITGB1 1.1192 | SIPA1L1 1.1047 | RASGRP2 1.1008 | VAMP2 1.0699 | PSEN1 1.0274 | SNAP23 1.0066 | QDPR 1.0027 | USP14 0.9734 | PEBP1 0.9211 | ENO2 0.9115 | SYP 0.8425 | BSN 0.8423 | ITGA5 0.8380 | LIN7C 0.6405 | SYNJ1 0.6101 | ZMYND19 0.4247 | CHRNB3 0.3372 | DKFZp586I031 | MT-ND5 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
olfactory lobe development (boxplot) | 28 | 28 | 4.171525349203491 | 1.5128369470041036E-5 | 0.002384426233245823 | 0.0 | ARX 6.2843 | ERBB4 3.2809 | SLIT1 3.2641 | ROBO2 3.0085 | NR2E1 2.8955 | FEZF1 2.8875 | SLIT2 2.8500 | SLIT3 2.4489 | PCNT 2.3313 | OGDH 2.3215 | EXT1 2.2085 | SKI 2.1799 | ROBO1 2.1673 | HTT 2.0106 | ID2 1.6791 | DPYSL2 1.6469 | LRRK2 1.5730 | FGFR1 1.5730 | AGTPBP1 1.5597 | DICER1 1.4798 | DLX2 1.4133 | RPGRIP1L 1.3825 | WNT5A 1.3655 | SALL3 1.3649 | SRF 1.1778 | SALL1 1.1703 | EOMES 1.0250 | EFNA2 0.9726 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
transferase activity, transferring pentosyl groups (boxplot) | 48 | 53 | 4.155577948366303 | 1.6223314902807928E-5 | 0.0024770973942224855 | 0.0 | SIRT1 7.4176 | TIPARP 3.3907 | PRTFDC1 3.1034 | QTRT1 3.0383 | APRT 3.0059 | XYLT1 2.9735 | PARP6 2.9341 | XXYLT1 2.7689 | DFFB 2.7630 | PNP 2.7166 | UMPS 2.6508 | PPAT 2.6276 | PARP14 2.5615 | TNKS2 2.2784 | ART4 2.2287 | SIRT2 2.1358 | SIRT6 2.0739 | NAPRT1 2.0549 | ART1 2.0484 | ART5 | UPP2 2.0278 | GXYLT1 1.9454 | PARP4 1.9415 | PARP11 1.8498 | QPRT 1.8419 | PARP1 1.8367 | PARP15 1.7997 | TNKS 1.7942 | MTAP 1.7397 | ART3 1.6775 | C6orf108 1.6763 | ZC3HAV1 1.6623 | UPP1 1.5954 | PARP12 1.4995 | XYLT2 1.3792 | PARP3 1.3621 | PARP10 1.3309 | GXYLT2 1.3159 | PARP8 1.2526 | PARP9 1.0544 | TYMP 1.0412 | SIRT3 0.9975 | PARP16 0.9595 | SIRT4 0.9183 | PARP2 0.9028 | QTRTD1 0.8889 | SIRT5 0.8488 | NAMPT 0.8179 | HPRT1 0.8115 | DO | NAMPTL | RCL | RP11-92J19.4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
olfactory bulb development (boxplot) | 27 | 27 | 4.127224068608204 | 1.8358429686005096E-5 | 0.002718160225630936 | 0.0 | ARX 6.2843 | ERBB4 3.2809 | SLIT1 3.2641 | ROBO2 3.0085 | NR2E1 2.8955 | FEZF1 2.8875 | SLIT2 2.8500 | SLIT3 2.4489 | PCNT 2.3313 | OGDH 2.3215 | EXT1 2.2085 | SKI 2.1799 | ROBO1 2.1673 | ID2 1.6791 | DPYSL2 1.6469 | LRRK2 1.5730 | FGFR1 1.5730 | AGTPBP1 1.5597 | DICER1 1.4798 | DLX2 1.4133 | RPGRIP1L 1.3825 | WNT5A 1.3655 | SALL3 1.3649 | SRF 1.1778 | SALL1 1.1703 | EOMES 1.0250 | EFNA2 0.9726 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
phospholipid transporter activity (boxplot) | 29 | 29 | 4.124888867705246 | 1.854569054260402E-5 | 0.002718160225630936 | 0.0 | ABCA1 5.6064 | ATP9A 3.8389 | PITPNC1 3.8379 | ATP11A 3.7283 | ATP8A2 3.6048 | ATP8B2 3.0740 | PITPNM3 2.8095 | PITPNA 2.6811 | PITPNB 2.3808 | ATP10D 2.2069 | ATP10A 2.1905 | PLSCR4 2.0968 | ABCG1 2.0741 | ATP8B4 1.9597 | ABCA4 1.9148 | ATP9B 1.7613 | CETP 1.6214 | ATP10B 1.5905 | PITPNM1 1.5262 | ATP8B1 1.3825 | ATP11B 1.2915 | ABCA7 1.2907 | ATP8A1 1.2627 | PCTP 1.1922 | ATP8B3 0.9821 | PLSCR1 0.9775 | PLSCR2 0.9222 | PLSCR3 0.8330 | ATP11C 0.5439 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cholesterol efflux (boxplot) | 18 | 18 | 4.0781754760992115 | 2.2695251775006753E-5 | 0.0031682571477909425 | 0.0 | SIRT1 7.4176 | ABCA1 5.6064 | SREBF2 2.9595 | NFKBIA 2.3376 | EGF 2.1937 | PTCH1 2.1082 | ABCG1 2.0741 | LRP1 1.8683 | PLA2G10 1.7764 | CETP 1.6214 | PON1 1.5922 | APOE 1.4398 | LAMTOR1 1.3465 | ADIPOQ 1.3289 | NR1H3 1.3265 | SHH 1.2438 | NR1H2 1.1632 | IRAK1 1.0945 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
transmembrane receptor protein kinase activity (boxplot) | 83 | 83 | 4.07608596102244 | 2.2900046766416438E-5 | 0.0031682571477909425 | 0.0 | NTRK3 4.8124 | ROR1 3.4425 | ERBB4 3.2809 | EPHA6 3.2448 | ERBB2 3.2295 | INSR 3.1624 | ROS1 3.0136 | ALK 2.9520 | EGFR 2.8090 | FLT3 2.7949 | NTRK2 2.7766 | FGFR2 2.7650 | EPHA3 2.7107 | EPHB2 2.7088 | EPHB1 2.6334 | FLT1 2.6297 | MUSK 2.5943 | CRIM1 2.5875 | EPHA1 2.5465 | BMPR1A 2.4359 | EFEMP1 2.4217 | IGF1R 2.4090 | PDGFRL 2.3802 | ENG 2.2047 | EPHA5 2.1737 | LTK 2.0786 | ACVR2B 2.0747 | BMPR2 2.0562 | NTRK1 2.0462 | TYRO3 1.9521 | RET 1.9319 | IRS1 1.9115 | BMPR1B 1.9013 | TEK 1.8630 | MERTK 1.8314 | EPHA8 1.7658 | EFNA4 1.7569 | INSRR 1.7414 | TGFBR3 1.7014 | EPHA7 1.6962 | RYK 1.6892 | PTK7 1.6724 | EPHA4 1.6721 | EPHA10 1.6566 | FGFRL1 1.6492 | PDGFRA 1.6489 | DDR1 1.6458 | TIE1 1.6414 | ROR2 1.6347 | NRP2 1.6343 | ACVR1C 1.6115 | TGFBR2 1.5967 | NRP1 1.5851 | FGFR1 1.5730 | KDR 1.5543 | TRIM27 1.5287 | IGF2R 1.4885 | FGFR3 1.4587 | EPHB4 1.4218 | AXL 1.4159 | KIT 1.4147 | FKBP1A 1.3770 | EFNB3 1.2849 | FLT4 1.2760 | LTBP1 1.2633 | MST1R 1.2550 | ACVR2A 1.2534 | CSF1R 1.2307 | PDGFRB 1.2307 | DDR2 1.1922 | EPHA2 1.1715 | MET 1.1441 | FGFR4 1.1354 | TGFBR1 1.1193 | AMHR2 1.0921 | EFNA3 1.0625 | ACVR1 1.0582 | ERBB3 1.0409 | ACVRL1 0.8961 | ACVR1B 0.7753 | LTBP4 0.7647 | EPHB6 0.6660 | EPHB3 0.6149 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ovulation from ovarian follicle (boxplot) | 12 | 12 | 4.017258012266895 | 2.943962356405372E-5 | 0.0038876216414585533 | 0.0 | SIRT1 7.4176 | ADAMTS1 2.9721 | PLA2G4A 2.3298 | AGT 2.2659 | NRIP1 2.1803 | FOXO3 2.0675 | EDN2 1.8797 | AFP 1.7611 | NOS3 1.6288 | MMP19 1.5508 | LEP 1.4143 | PGR 1.2410 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
extracellular matrix structural constituent (boxplot) | 76 | 80 | 3.9915648622001347 | 3.281936496390969E-5 | 0.004219879400359546 | 0.0 | EMILIN2 4.7716 | COL11A2 4.6854 | COL15A1 3.8816 | IMPG2 3.5455 | FBLN1 3.1193 | IMPG1 2.8912 | COL4A2 2.8351 | PXDN 2.8160 | COL13A1 2.7836 | COL6A2 2.7393 | COL4A1 2.5872 | MUC4 2.5381 | WNT9A 2.5288 | ACAN 2.4524 | TINAGL1 2.4153 | FBLN2 2.3953 | COL19A1 2.3157 | MEPE 2.2564 | COL4A3 2.2501 | COL27A1 2.2485 | COL12A1 2.2318 | FBN3 2.1864 | COL14A1 2.1863 | OPTC 2.1772 | PRELP | COL24A1 2.1417 | MATN1 2.1263 | LAMB1 2.0735 | LAMA4 2.0531 | CD4 2.0421 | FBN1 1.9663 | COL9A1 1.9621 | FN1 1.9294 | LAMC1 1.9271 | MGP 1.9249 | COL5A1 1.9082 | WNT7B 1.8583 | AMBN 1.8458 | COL9A3 1.7829 | BGN 1.7750 | LUM 1.7679 | LAMA1 1.7275 | COL8A2 1.7125 | COL4A4 1.6590 | WNT3A 1.6407 | MATN3 1.6240 | STATH 1.6213 | MUC5B 1.5459 | DSPP 1.5302 | COL1A1 1.4835 | COL3A1 1.4690 | COL5A2 1.4504 | COL11A1 1.4339 | COL1A2 1.4123 | COL5A3 1.3492 | COL4A6 1.3398 | MUC6 1.3383 | COL9A2 1.3311 | COL2A1 1.3191 | COL4A5 1.3070 | KAL1 1.2799 | TECTB 1.2795 | EFEMP2 1.2636 | CHAD 1.2469 | ELN 1.1825 | TECTA 1.1635 | MFAP5 1.1177 | COMP 1.0103 | WNT4 0.9772 | MUC17 0.9758 | FBN2 0.9552 | TUFT1 0.9518 | TFPI2 0.8832 | CHI3L1 0.8801 | EMILIN1 0.8762 | AMELX 0.7680 | ENAM 0.4998 | AMELY | MUC3A | MUC5AC | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ionotropic glutamate receptor complex (boxplot) | 28 | 28 | 3.9815271017076896 | 3.423695583992803E-5 | 0.004289276057279188 | 0.0 | GRIK4 3.9399 | GRIA4 3.3765 | GRIK2 3.2889 | GRIN3A 3.1467 | SHANK1 3.1256 | GRID2 3.0003 | CACNG3 2.6709 | GRIA3 2.4068 | SHANK2 2.3841 | GRIN2B 2.2951 | CACNG4 2.2546 | CNIH2 2.1101 | GRIN2A 2.0931 | GRIN2C 1.9757 | CACNG7 1.9540 | CNIH3 1.8983 | GRIK1 1.8243 | DLG4 1.7370 | SHISA9 1.7162 | CACNG5 1.6745 | EPS8 1.4871 | GRIN2D 1.3766 | CACNG2 1.3692 | CACNG8 1.2699 | GRIN1 1.2637 | GRIA1 1.1475 | GRIN3B 1.0627 | GRIA2 0.9514 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
actomyosin (boxplot) | 53 | 53 | 3.9483178069430647 | 3.9351139696552906E-5 | 0.004806741713933938 | 0.0 | MYO1C 4.9972 | SEPT7 4.3221 | MYLK 3.2871 | SEPT11 3.2438 | SYNPO 2.9309 | MYO18A 2.8163 | NEBL 2.7784 | STX1A 2.7012 | ZYX 2.5465 | KAT2B 2.5358 | SEPT9 2.5051 | TPM3 2.4781 | PDLIM2 2.3613 | CDC42BPA 2.3339 | FHOD1 2.2999 | DLC1 2.2963 | MYH11 2.2753 | AMOT 2.2199 | LIMA1 2.0815 | ACTN1 2.0386 | HDAC4 1.9670 | GAS2L2 1.9360 | ENAH 1.8839 | TEK 1.8630 | SEPT12 1.8144 | MYH6 1.8142 | MYH7 1.8142 | MYL9 1.7057 | PGM5 1.7013 | FSCN1 1.6954 | SORBS1 1.6523 | GAS2L1 1.6509 | CDC42BPB 1.6242 | TPM1 1.5971 | MYL12B 1.5886 | MYO5A 1.5529 | MYH10 1.4980 | FERMT2 1.4965 | DAAM1 1.4884 | ACTN4 1.4437 | PDLIM7 1.3736 | SH2B2 1.3733 | TPM4 1.3177 | CNN2 1.2907 | MST1R 1.2550 | MYH9 1.1496 | ILK 1.1347 | ACTC1 1.1031 | DBN1 1.0367 | FHL3 0.9837 | ACTA1 0.9736 | SHROOM4 0.9493 | FBLIM1 0.5285 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cyclic nucleotide catabolic process (boxplot) | 17 | 17 | 3.94705536924809 | 3.9559132363864435E-5 | 0.004806741713933938 | 0.0 | PDE2A 3.7330 | PDE10A 3.5081 | PDE4B 3.1574 | PDE8A 3.0407 | CNP 2.9419 | PDE11A 2.9328 | PDE4D 2.8834 | PDE7B 2.6103 | PDE3A 2.3821 | PDE1C 2.1963 | PDE3B 1.7081 | PDE4C 1.4334 | PDE8B 1.3712 | PDE7A 1.2485 | PDE1B 1.1847 | PDE5A 1.1185 | PDE4A 0.7502 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of synaptic plasticity (boxplot) | 88 | 88 | 3.9458769650506675 | 3.975421756940989E-5 | 0.004806741713933938 | 0.0 | CNTN4 4.2048 | PSEN2 3.3139 | GRIK2 3.2889 | CPLX2 3.2544 | TNR 3.0413 | RASGRF1 2.9288 | NR2E1 2.8955 | MMP9 2.7841 | PPFIA3 2.7612 | EPHB2 2.7088 | HRAS 2.6539 | STXBP1 2.6367 | YWHAH 2.6079 | NETO1 2.5980 | GRID2IP 2.4971 | PLK2 2.4876 | CTNND2 2.4273 | PPP3CB 2.4174 | VGF 2.3948 | NPTN 2.3588 | GRIN2B 2.2951 | CNTN2 2.2820 | AGT 2.2659 | CAMK2B 2.2519 | MAP1B 2.2447 | CPEB1 2.2018 | JPH3 2.1788 | CAMK2A 2.1496 | ARC 2.1147 | GRIN2A 2.0931 | CDC20 2.0817 | SHANK3 2.0446 | HTT 2.0106 | SNCA 1.9846 | PTGS2 1.9806 | RGS14 1.9785 | GRM5 1.9765 | RIMS1 1.9395 | SLC24A2 1.9291 | EGR2 1.8938 | UNC13B 1.8915 | CD38 1.8553 | NCDN 1.8469 | GRIK1 1.8243 | NEUROD2 1.8013 | PRKCZ 1.7929 | ANAPC2 1.7859 | DLG4 1.7370 | SHISA9 1.7162 | ADORA1 1.7070 | UNC13A 1.6800 | SERPINE2 1.6272 | RAPGEF2 1.6242 | DRD2 1.5853 | CDK5 1.5715 | GIPC1 1.5412 | ABHD6 1.5138 | DRD1 1.4777 | MGLL 1.4752 | GIP 1.4524 | APOE 1.4398 | CALB1 1.4175 | SYNGR1 1.4155 | P2RX3 1.3783 | BHLHE40 1.3567 | CRHR1 1.3545 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | BDNF 1.2240 | RAB11A 1.2181 | BCAN 1.2096 | GFAP 1.2059 | SRF 1.1778 | SYNGAP1 1.1743 | PMCH 1.1212 | YWHAG 1.1107 | SIPA1L1 1.1047 | MYLK2 1.0997 | PLAT 1.0689 | DBN1 1.0367 | PSEN1 1.0274 | KRAS 0.9975 | S100B 0.9943 | NRAS 0.9279 | SYP 0.8425 | KCNJ10 0.8338 | EGR1 0.5440 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
glycerol ether metabolic process (boxplot) | 113 | 113 | 3.917200557233962 | 4.479160848491759E-5 | 0.005089576722262961 | 0.0 | SIRT1 7.4176 | LPIN2 5.2136 | TXNL1 3.9971 | PDIA5 3.7819 | CAV1 3.7656 | FAR2 3.4933 | AGMO 3.1160 | APOC3 3.0248 | LPCAT1 3.0227 | ELOVL6 2.9754 | PRKACB 2.9293 | GPD1 2.7351 | ACLY 2.7017 | PPP1CB 2.6090 | APOA5 2.5911 | AGPAT4 2.5633 | ABHD5 2.5629 | CDIPT 2.5282 | TXNDC2 2.5233 | GPAT2 2.5064 | ELOVL2 2.4805 | MOGAT3 2.4686 | CAV3 2.3881 | PCK1 2.3007 | ACSL1 2.2283 | SLC27A5 2.1872 | LCLAT1 2.1535 | LPIN1 2.1486 | ELOVL1 2.0817 | ACSL5 2.0627 | AGPAT6 2.0214 | AGPAT2 2.0126 | PLCE1 2.0072 | SLC22A4 1.9862 | TMX3 1.9767 | PDIA2 1.9756 | LPL 1.9485 | DGKK 1.9475 | TXNDC5 1.9456 | ELOVL7 1.9273 | MOGAT1 1.9020 | GPX1 1.8947 | ALMS1 1.8311 | AGPS 1.8230 | CPS1 1.8058 | SLC25A1 1.8029 | PNPLA2 1.7743 | PRKACG 1.7616 | AGPAT3 1.7230 | GK 1.7138 | DGAT1 1.7111 | PEX7 1.6864 | ACSL6 1.6845 | ANG 1.6605 | PDIA6 1.6347 | AGPAT5 1.6333 | LIPF 1.6322 | PNPLA3 1.6241 | TXNDC8 1.6232 | CETP 1.6214 | ACSL3 1.6086 | LIPC 1.6053 | CDS2 1.6034 | AGPAT1 1.5913 | DGKD 1.5653 | NKX2-3 1.5542 | HSD17B12 1.5489 | PDIA4 1.5403 | FAR1 1.5101 | TXN 1.5088 | TECR 1.5086 | TXN2 1.5012 | PNLIPRP2 1.4930 | PCSK9 1.4808 | MGLL 1.4752 | APOE 1.4398 | GPAM 1.4378 | DGAT2 1.4198 | CYP2E1 1.3837 | PLIN1 1.3583 | APOC1 1.3441 | TMEM86B 1.3238 | FABP4 1.3200 | PPP1CA 1.3052 | ACSL4 1.2837 | APOB 1.2451 | APOH 1.2376 | MTTP 1.2284 | GNPAT 1.2058 | LIPE 1.1888 | FASN 1.1849 | CPT1A 1.1834 | CEL 1.1461 | ELOVL4 1.1167 | PGS1 1.1094 | INSIG2 1.0701 | GPD1L 1.0398 | PPP1CC 1.0164 | CDS1 1.0042 | MOGAT2 0.9999 | QSOX1 0.9486 | APOA2 0.8951 | ELOVL5 0.8407 | ACACA 0.8142 | DNAJC10 0.8057 | PRKACA 0.6979 | PDIA3 0.6933 | CAT 0.6876 | AGPAT9 0.6685 | INSIG1 0.6516 | P4HB 0.6423 | ELOVL3 0.6419 | G6PC 0.6297 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
T cell selection (boxplot) | 25 | 25 | 3.9046212140344565 | 4.718654101365516E-5 | 0.005239850895289071 | 0.0 | HLA-DMA 4.6143 | FAS 3.2882 | CARD11 3.1018 | ITPKB 2.8294 | THEMIS 2.7728 | GLI3 2.3270 | CCR7 2.3166 | IL15 2.2242 | DOCK2 2.2237 | BCL2 2.1766 | JAG2 2.1763 | CD28 2.1569 | CD3D 2.1205 | CD3E 2.1205 | SYK 2.1149 | CD4 2.0421 | BCL11B 1.8758 | CD1D 1.5801 | MINK1 1.4611 | PTPRC 1.4182 | ZAP70 1.3847 | SHH 1.2438 | SPN 1.2252 | SRF 1.1778 | CD74 1.0390 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
induction of apoptosis by extracellular signals (boxplot) | 121 | 121 | 3.902426716949553 | 4.76165379612592E-5 | 0.005239850895289071 | 0.0 | YWHAE 4.5001 | BTK 4.4391 | CAV1 3.7656 | DAP 3.6330 | KALRN 3.6105 | PLEKHG2 3.4715 | PSEN2 3.3139 | FAS 3.2882 | MAP3K5 3.1884 | MAPK9 3.1472 | TNF 3.0639 | BAX 3.0299 | PREX1 2.9502 | RASGRF1 2.9288 | ARHGEF3 2.8881 | AKAP13 2.8539 | TIAM1 2.8400 | BID 2.7152 | NGFRAP1 2.6339 | CRADD 2.4878 | MCF2 2.4868 | RASGRF2 2.4633 | TIAM2 2.4489 | FGD2 2.4194 | VDR 2.3912 | CASP3 2.3272 | TNFRSF10B 2.3119 | SSTR3 2.2634 | NGFR 2.2572 | CAMK2B 2.2519 | ARHGEF18 2.2107 | PRKCA 2.1719 | MAPK8 2.1614 | CD28 2.1569 | RPS27A 2.1523 | TRIO 2.1284 | CD3E 2.1205 | ARHGEF9 2.0887 | CFLAR 2.0744 | RIPK1 2.0686 | FGD4 2.0673 | ARHGEF11 2.0462 | NGF 2.0438 | ITSN1 2.0433 | VAV2 1.9727 | OBSCN 1.9276 | RAC1 1.9125 | TRADD 1.8740 | CD38 1.8553 | VAV3 1.8406 | DAXX 1.8243 | RIPK3 1.8128 | FASLG 1.8023 | IFI27 1.7714 | ABR 1.7595 | ADORA1 1.7070 | DIABLO 1.6957 | BAD 1.6791 | ITGB3BP 1.6635 | ARHGEF4 1.6452 | SQSTM1 1.6098 | PDCD6 1.5772 | PLEKHG5 1.5723 | ARHGEF16 1.5691 | MCF2L 1.5518 | SST 1.5496 | SMPD2 1.5327 | SOS2 1.5227 | DAP3 1.4939 | TM2D1 1.4754 | FGD3 1.4630 | NET1 1.4291 | CASP2 1.4160 | NDUFA13 1.4126 | TNFSF10 1.4107 | FGD1 1.4085 | DPF2 1.3906 | VAV1 1.3902 | FADD 1.3890 | PSENEN 1.3748 | DAPK1 1.3354 | UBC 1.3324 | TNFRSF25 1.3156 | NGEF 1.3111 | ADORA2A 1.3027 | UBA52 1.2944 | ARHGEF12 1.2882 | NCSTN 1.2737 | BCL2L11 1.2301 | PTH 1.2270 | SPN 1.2252 | DEDD2 1.2130 | MAGED1 1.2092 | CASP10 1.1822 | CASP8 1.1822 | TNFRSF1A 1.1656 | CD5 1.1624 | SOS1 1.1496 | SORT1 1.1418 | ARHGEF7 1.1278 | TRAF6 1.1053 | APH1B 1.0991 | ARHGEF2 1.0873 | APH1A 1.0646 | TRAF2 1.0448 | PSEN1 1.0274 | DEDD 1.0030 | FASTK 0.9969 | TNFRSF10A 0.9347 | TICAM1 0.9140 | ARHGEF17 0.9078 | SENP1 0.8464 | CRH 0.8287 | AATF 0.8142 | TNFSF12 0.8115 | BAK1 0.7850 | ARHGAP4 0.7810 | UBB 0.7504 | CASP8AP2 0.6842 | ARHGEF6 0.6228 | ECT2 0.5904 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cell shape (boxplot) | 97 | 98 | 3.889861885162825 | 5.015064569580119E-5 | 0.005326870758036622 | 0.0 | SEPT7 4.3221 | ALDOA 4.0025 | ARAP1 3.7330 | CCL24 3.7243 | FYN 3.7055 | CDC42EP3 3.5970 | TAOK2 3.3686 | FES 3.1088 | VEGFA 3.0488 | ANXA7 2.9900 | ARHGAP15 2.9085 | SHROOM3 2.7639 | PLXNB2 2.7490 | LST1 2.7317 | CDC42EP1 2.6574 | F2 2.6432 | BRWD1 2.5416 | ITGB2 2.5057 | PALM2 2.4365 | FGD2 2.4194 | ARAP3 2.3645 | HEXB 2.3391 | GNA12 2.3370 | DLC1 2.2963 | AKAP2 2.2927 | ARHGEF18 2.2107 | ATP10A 2.1905 | CDC42SE1 2.1770 | WDPCP 2.1418 | GAS7 2.0984 | FGD4 2.0673 | SEMA3E 2.0638 | EPB42 2.0572 | FGD5 1.9928 | PDPN 1.9883 | CYFIP1 1.9503 | FN1 1.9294 | C21orf2 1.9098 | MYO10 1.7867 | VIL1 1.7405 | WASF3 1.7392 | RHOJ 1.7352 | CCL13 1.7344 | RHOU 1.7224 | HPN 1.7202 | PALM 1.7163 | IL6 1.7153 | ICAM1 1.6718 | BRWD3 1.6548 | CDC42EP5 1.6302 | CFDP1 1.6091 | GNA13 1.6039 | MYL12B 1.5886 | ARHGAP35 1.5865 | RASA1 1.5836 | KDR 1.5543 | FGD6 1.5470 | SH3KBP1 1.5425 | MYH10 1.4980 | FERMT2 1.4965 | HCK 1.4790 | FGD3 1.4630 | MYH14 1.4431 | FGD1 1.4085 | SEMA4D 1.3860 | PTK2 1.3822 | DIAPH1 1.3602 | TBCCD1 1.3375 | CDC42EP2 1.3369 | S100A13 1.3048 | CCL11 1.3027 | CCL7 1.3027 | LIMD1 1.2921 | GAS2 1.2821 | PRPF40A 1.2756 | SPTA1 1.2678 | CDC42EP4 1.2590 | CSF1R 1.2307 | FGR 1.1781 | BAMBI 1.1573 | SLC26A5 1.1553 | MYH9 1.1496 | RHOQ 1.1486 | EZR 1.1330 | ITGA7 1.1296 | PTK2B 1.1280 | PALMD 1.0917 | ERMN 1.0218 | CORO1A 0.9727 | BVES 0.9470 | CCL3 0.9396 | CDC42SE2 0.8480 | FMNL1 0.7139 | FAM40B 0.6984 | CCL2 | PLXNB1 0.6552 | FMNL3 0.5546 | FBLIM1 0.5285 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of lipid transport (boxplot) | 24 | 24 | 3.8859295593950502 | 5.0969532281675E-5 | 0.005326870758036622 | 0.0 | SIRT1 7.4176 | ABCA1 5.6064 | PLA2R1 3.4416 | NFKBIA 2.3376 | PTCH1 2.1082 | ABCG1 2.0741 | ACSL5 2.0627 | OXT 1.9195 | IL1B 1.8813 | LRP1 1.8683 | P2RX7 1.8574 | PLA2G10 1.7764 | TNFSF11 1.7065 | CYP4A11 1.6857 | PON1 1.5922 | P2RX4 1.5095 | APOE 1.4398 | P2RY2 1.4186 | ADIPOQ 1.3289 | NR1H3 1.3265 | LIPG 1.3223 | TNFRSF11A 1.2162 | NR1H2 1.1632 | CYP4F2 1.0426 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
endocytic vesicle (boxplot) | 127 | 131 | 3.8762200568720533 | 5.304587118226678E-5 | 0.005399627637428239 | 0.0 | ABCA1 5.6064 | VAMP1 4.1635 | PICALM 3.8576 | CAV1 3.7656 | B2M 3.6670 | NRXN1 3.6097 | GRIA4 3.3765 | RILP 3.3070 | DNM2 3.0383 | APOA1 3.0248 | CUBN 2.9709 | TLR1 2.8628 | TLR6 2.8628 | LPAR2 2.8343 | EGFR 2.8090 | SLC18A3 2.7603 | RAB5A 2.6894 | SYT1 2.6792 | CACNG3 2.6709 | TLR9 2.5867 | CAMK2D 2.5615 | LRP2 2.5159 | MYO1E 2.5057 | GRIA3 2.4068 | DPP4 2.3359 | HLA-F 2.2828 | CD207 2.2783 | O3FAR1 2.2565 | CACNG4 2.2546 | CAMK2B 2.2519 | RAB11FIP4 2.2498 | GLP1R 2.2306 | AMOT 2.2199 | AP2A1 2.2056 | CAMK2G 2.1818 | CALR 2.1592 | RPS27A 2.1523 | CAMK2A 2.1496 | SYK 2.1149 | ITGB5 2.0784 | EHD1 2.0670 | ITSN1 2.0433 | VPS11 2.0160 | OCRL 2.0031 | RAB35 1.9916 | SFTPD 1.9782 | FLOT2 1.9629 | DRD3 1.9435 | AP2B1 1.9360 | MYO6 1.9297 | LDLR 1.9157 | ANXA3 1.9125 | RAB11FIP1 1.9080 | AP2A2 1.8451 | LPAR1 1.8285 | RABEP1 1.7967 | ITGAV 1.7509 | SLC11A1 1.7405 | DLG4 1.7370 | SGIP1 1.7021 | TAPBP 1.6801 | HLA-B 1.6543 | TIRAP 1.6414 | NOS3 1.6288 | NLGN3 1.5936 | TAP1 1.5897 | TAP2 | DRD2 1.5853 | TLR7 1.5479 | GIPC1 1.5412 | ADAM8 1.5178 | CYBB 1.5177 | HLA-G 1.5161 | UNC93B1 1.5133 | IRGM 1.4964 | IGF2R 1.4885 | CD36 1.4667 | CLTA 1.4478 | LDLRAP1 1.4279 | HLA-A | DMBT1 1.4123 | PICK1 1.3992 | PIK3C2B 1.3906 | CACNG2 1.3692 | GOLIM4 1.3620 | NCF2 1.3613 | AP2S1 1.3442 | SEC61B 1.3364 | UBC 1.3324 | LCK 1.3129 | NCF4 1.3088 | MTSS1 1.3065 | RAB7A 1.3020 | UBA52 1.2944 | HLA-E 1.2721 | CACNG8 1.2699 | TYRP1 1.2671 | EPN2 1.2666 | SYT2 1.2635 | APOB 1.2451 | SEC61G 1.2319 | NOSTRIN 1.1758 | RAB5B 1.1593 | WASL 1.1528 | GRIA1 1.1475 | HLA-C 1.1295 | INPP5B 1.1013 | SEC61A2 1.1004 | RAB5C 1.0789 | VAMP2 1.0699 | CTLA4 1.0433 | CYBA 1.0419 | NCF1 1.0210 | CORO1A 0.9727 | EHD3 0.9577 | GRIA2 0.9514 | FCGR1A 0.9281 | ANXA11 0.8916 | TF 0.8881 | SEC61A1 0.8280 | FCGR1B 0.7513 | UBB 0.7504 | RALA 0.7339 | MDM2 0.7327 | EPS15 0.7236 | PDIA3 0.6933 | STX12 0.6580 | AP2M1 0.5064 | HYAL2 0.2244 | ECM29 | VAMP7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
calmodulin binding (boxplot) | 160 | 161 | 3.8641628872933222 | 5.573541035763796E-5 | 0.005557616632804471 | 0.0 | MYO1C 4.9972 | IQGAP2 3.8713 | MYLK 3.2871 | MYO1D 3.2744 | RYR2 3.1737 | CAMK1 2.9695 | PLCB3 2.9532 | CACNA1C 2.8754 | ATP2B2 2.8342 | ITPKB 2.8294 | SPATA17 2.8093 | SLC8A1 2.7718 | SPTBN1 2.7693 | SPTAN1 2.7684 | SYT1 2.6792 | RIT2 2.6439 | PLCB1 2.6151 | KCNQ1 2.5850 | KCNH1 2.5742 | RYR3 2.5711 | CAMK2D 2.5615 | CNN3 2.5363 | ADD1 2.5292 | CAMK4 2.5094 | MYO1E 2.5057 | RASGRF2 2.4633 | ITPKA 2.4578 | DAPK2 2.4457 | TTN 2.4386 | CAMK1D 2.4333 | PPP3CB 2.4174 | MYO9B 2.3989 | KCNH5 2.3674 | INVS 2.3332 | PCNT 2.3313 | NOS1 2.3035 | ATP2B4 2.2998 | MYH11 2.2753 | SCN5A 2.2668 | CALD1 2.2528 | CAMK2B 2.2519 | TRPV1 2.1980 | PDE1C 2.1963 | ADD3 2.1906 | CAMK2G 2.1818 | ADCY3 2.1650 | CAMK2A 2.1496 | MYO3A 2.1330 | ITPKC 2.1296 | MAP6D1 2.1225 | KCNN3 2.0701 | ASPM 2.0599 | MYO5B 2.0328 | MYO1B 2.0278 | TRPV4 2.0262 | EEA1 1.9640 | CAMKK1 1.9501 | PPP3CC 1.9488 | PPP3R1 1.9487 | SNTB1 1.9473 | CACNA1A 1.9305 | MYO6 1.9297 | OBSCN 1.9276 | TRPM4 1.9153 | SLC8A3 1.9072 | STRN 1.8799 | CAMKK2 1.8746 | KCNN1 1.8466 | PIK3R1 1.8351 | MYH6 1.8142 | MYH7 1.8142 | MYO10 1.7867 | ADD2 1.7611 | ADCY1 1.7392 | CAMK1G 1.7370 | ATP2B3 1.7173 | SMTNL1 1.7062 | RGS1 1.7062 | MYO7A 1.7012 | MYH15 1.7006 | RGS4 1.6526 | EWSR1 1.6509 | MARCKS 1.6411 | MYO5C 1.6330 | NOS3 1.6288 | GAP43 1.6161 | MYO1A 1.6056 | CDK5RAP2 1.6005 | EEF2K 1.5954 | AEBP1 1.5865 | RYR1 1.5561 | MYO5A 1.5529 | MYO1G 1.5496 | PCDP1 1.5415 | PDE1A 1.5160 | KCNN4 1.5095 | MYH1 1.5065 | MYH2 1.5065 | SPHK1 1.5010 | ENKUR 1.5003 | MYH10 1.4980 | PHKG2 1.4975 | SLC8A2 1.4933 | TRPV5 1.4897 | CEP97 1.4746 | ATPIF1 1.4743 | KCNN2 1.4571 | MYO1F 1.4447 | MYH14 1.4431 | PPP3CA 1.4235 | CASK 1.4083 | ARPP21 1.4062 | EPB41 1.3904 | MAP6 1.3522 | STRN3 1.3375 | SNTB2 1.3363 | DAPK1 1.3354 | RIT1 1.3063 | NOS2 1.3024 | GEM 1.3008 | CNN2 1.2907 | IQGAP1 1.2792 | GRIN1 1.2637 | NRGN 1.2599 | CTH 1.2336 | TJP1 1.2276 | SLC9A1 1.1993 | RRAD 1.1966 | PDE1B 1.1847 | MYH13 1.1562 | MYH4 1.1555 | MYH8 1.1555 | MYH9 1.1496 | REM1 1.1465 | MYLK2 1.0997 | MAP2 1.0970 | UBR4 1.0956 | VAMP2 1.0699 | MYH3 1.0276 | PHKG1 1.0042 | AKAP5 0.9641 | RGS2 0.9397 | ATP2B1 0.9361 | IQCB1 0.9071 | PHKA1 0.8977 | USP6 0.8920 | IQGAP3 0.8907 | PHKA2 0.8769 | RGS16 0.8763 | EDF1 0.8227 | PHKB 0.8149 | MARCKSL1 0.8048 | MYO15A 0.7632 | PNCK 0.7558 | CAMKV 0.7390 | NDUFAF4 0.6689 | STRN4 0.5986 | TRPV6 0.5852 | SNTA1 0.5644 | CNN1 0.5456 | SRY | ||||||||||||||||||||||||||||||||||||||||||||||
cAMP catabolic process (boxplot) | 15 | 15 | 3.8636201158622576 | 5.585945933161973E-5 | 0.005557616632804471 | 0.0 | PDE2A 3.7330 | PDE10A 3.5081 | PDE4B 3.1574 | PDE8A 3.0407 | PDE11A 2.9328 | PDE4D 2.8834 | PDE7B 2.6103 | PDE3A 2.3821 | PDE1C 2.1963 | PDE3B 1.7081 | PDE4C 1.4334 | PDE8B 1.3712 | PDE7A 1.2485 | PDE1B 1.1847 | PDE4A 0.7502 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
striated muscle contraction (boxplot) | 52 | 54 | 3.8367287520738813 | 6.234202794597188E-5 | 0.00597261075576507 | 0.0 | ALDOA 4.0025 | KBTBD10 3.9041 | MAP2K6 3.6149 | PSEN2 3.3139 | TCAP 3.2295 | RYR2 3.1737 | TNNC2 3.1678 | TNF 3.0639 | VEGFB 2.9601 | ANK2 2.8691 | SMPX 2.6933 | RYR3 2.5711 | CAMK2D 2.5615 | TTN 2.4386 | NOS1 2.3035 | SCN5A 2.2668 | NKX2-5 2.2385 | HOMER1 2.1943 | ARHGEF11 2.0462 | TNNI3 2.0145 | TNNT1 | TNNI2 1.9767 | GAA 1.9633 | MYBPC3 1.9461 | PPP1R13L 1.9069 | MYL3 1.8709 | TNNC1 1.8440 | MYH6 1.8142 | ARG2 1.7953 | TNNT3 1.6778 | DTNA 1.6062 | TPM1 1.5971 | CASQ2 1.5967 | RCSD1 1.5736 | MB 1.4850 | CACNA1S 1.3954 | MYL1 1.3574 | PIK3CA 1.3325 | SCN1B 1.3219 | CHRNA1 1.3109 | MYL4 1.2440 | RPS6KB1 1.2260 | ACTC1 1.1031 | MYLK2 1.0997 | TAZ 1.0762 | ADRBK1 1.0662 | SCN2B 1.0517 | ADRB2 1.0467 | TLR4 0.9855 | SMAD5 0.8825 | PGAM2 0.8579 | IKBKB 0.7521 | MAP2K3 0.5826 | ID2B | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
learning (boxplot) | 83 | 83 | 3.8137808518389638 | 6.842841796417254E-5 | 0.006429639426402828 | 0.0 | FYN 3.7055 | NRXN1 3.6097 | AMPH 3.4482 | PARK2 3.3357 | FOXP2 3.2196 | SHANK1 3.1256 | TNR 3.0413 | GRM7 2.8268 | NTRK2 2.7766 | EPHB2 2.7088 | HRAS 2.6539 | PLCB1 2.6151 | NETO1 2.5980 | COMT 2.5550 | SLC12A5 2.5026 | CTNND2 2.4273 | PPP3CB 2.4174 | GRIN2B 2.2951 | CNTN2 2.2820 | GLP1R 2.2306 | HMGCR 2.1730 | APP 2.1303 | ARC 2.1147 | CACNA1E 2.0970 | GRIN2A 2.0931 | ATXN1 2.0856 | GABRA5 2.0812 | SHANK3 2.0446 | HTT 2.0106 | ATAD1 2.0096 | RGS14 1.9785 | GRM5 1.9765 | TH 1.9742 | DRD3 1.9435 | SLC24A2 1.9291 | JUN 1.8868 | MAPK8IP2 1.8627 | DRD4 1.8319 | DBH 1.8135 | NEUROD2 1.8013 | PPP1R1B 1.8013 | PPT1 1.7921 | GRM4 1.7819 | PRKAR2B 1.7791 | DLG4 1.7370 | TANC1 1.7362 | PTN 1.7220 | HIF1A 1.6618 | CHST10 1.6519 | TAC1 1.6069 | NLGN3 1.5936 | DRD2 1.5853 | CDK5 1.5715 | FOXP3 1.5343 | STRA6 1.5142 | FOXB1 1.5142 | FOS 1.5019 | ADRA1B 1.4817 | DRD1 1.4777 | SLC6A1 1.4647 | CLN8 1.4407 | CRHR1 1.3545 | TACR1 1.3533 | VDAC1 1.3400 | BTG2 1.3309 | CLN3 1.3063 | DRD5 1.2989 | NF1 1.2913 | GRIN1 1.2637 | ATP1A3 1.1872 | PDE1B 1.1847 | SRF 1.1778 | SYNGAP1 1.1743 | FOSL1 1.1638 | AAAS 1.1523 | BCHE 1.1249 | KRAS 0.9975 | CHRNB2 0.9425 | NRAS 0.9279 | ADAM2 0.9271 | RIC8A 0.6441 | SYNJ1 0.6101 | ATP1A2 0.4943 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
striated muscle cell development (boxplot) | 76 | 78 | 3.7999114549750663 | 7.237389872227773E-5 | 0.006672054135038659 | 0.0 | GPHN 5.9364 | MYPN 3.2513 | ERBB2 3.2295 | TCAP | VEGFA 3.0488 | ANKRD1 2.9349 | PROX1 2.8868 | CAV2 2.8160 | NEBL 2.7784 | CHAT 2.7603 | MUSK 2.5943 | COL4A1 2.5872 | TTN 2.4386 | FOXP1 2.3270 | CHRNB1 2.2963 | MYH11 2.2753 | NKX2-5 2.2385 | MYO18B 2.2179 | CACNB2 2.2123 | HOMER1 2.1943 | CXADR 2.1888 | SKI 2.1799 | DNER 2.1720 | LRP4 2.1606 | ACTB 2.1337 | APP 2.1303 | MYOZ1 2.0827 | PDZRN3 2.0541 | XIRP1 2.0504 | MEF2C 2.0426 | WNT10B 2.0180 | MYBPC3 1.9461 | TNC 1.9083 | ACTG1 1.9056 | GPX1 1.8947 | AFG3L2 1.8657 | RCAN1 1.8416 | MYH6 1.8142 | TMOD1 1.7664 | LEF1 1.7470 | MYLK3 1.7219 | PDGFRA 1.6489 | TPM1 1.5971 | MYOG 1.5902 | CAPN3 1.5788 | LRRK2 1.5730 | KRT19 1.5729 | NEURL2 1.5580 | RYR1 1.5561 | MYL2 1.5502 | KIAA1161 1.5218 | MYH10 1.4980 | LAMB2 1.4979 | MEF2A 1.4880 | F2R 1.4291 | PPP3CA 1.4235 | DNAJA3 1.4206 | CACNA1S 1.3954 | CACNG2 1.3692 | ALS2 1.3539 | CHRNA1 1.3109 | COL4A5 1.3070 | MYOD1 1.2690 | DVL1 1.2676 | PDGFRB 1.2307 | TNNT2 1.2243 | DOK7 1.2147 | SRF 1.1778 | OBSL1 1.1569 | BMP10 1.1425 | ITGB1 1.1192 | ACTC1 1.1031 | SDC1 1.0557 | NRD1 1.0284 | ACTA1 0.9736 | PTCD2 0.9115 | SNTA1 0.5644 | HNTN1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cation channel complex (boxplot) | 123 | 123 | 3.792601450845226 | 7.453865745876698E-5 | 0.006744368154509916 | 0.0 | SCN3B 4.2468 | SCN2A 3.6519 | KCND3 3.5097 | KCNA5 3.3453 | KCNMA1 3.3055 | KCNA7 3.2839 | KCNJ4 3.2311 | RYR2 3.1737 | CNTNAP2 3.1556 | CACNB4 3.1376 | KCNJ5 3.0325 | CACNA1G 3.0242 | KCNQ5 2.9323 | CACNA1C 2.8754 | KCNQ4 2.8155 | AKAP6 2.7555 | CACNG3 2.6709 | KCNMB2 2.6357 | SCN11A 2.6313 | PEX5L 2.5959 | KCNQ1 2.5850 | KCNH1 2.5742 | CNGB1 2.5546 | SCN9A 2.5308 | CACNA1H 2.4410 | KCNMB3 2.4149 | SESTD1 2.4004 | KCNC4 2.3714 | CNTN2 2.2820 | CATSPERD 2.2698 | SCN5A 2.2668 | KCNE2 2.2438 | CACNB2 2.2123 | KCNQ3 2.2037 | SCN8A 2.1612 | CACNA1D 2.1182 | CACNA1E 2.0970 | HCN2 2.0858 | CATSPERB 2.0624 | KCNJ6 2.0282 | CACNA2D1 1.9982 | CACNG7 1.9540 | KCNMB4 1.9400 | CACNA1A 1.9305 | KCNB2 1.9269 | KCNT2 1.9253 | KCNT1 1.9150 | KCNA2 1.8775 | KCNC1 1.8772 | SCN1A 1.8708 | CATSPER1 1.8550 | CACNA1B 1.8481 | KCNN1 1.8466 | CATSPERG 1.8461 | KCNE1 1.8416 | CACNG1 1.8336 | KCNK1 1.8306 | KCNIP2 1.8243 | KCNH2 1.8168 | CNGA2 1.8158 | KCNC2 1.8152 | CATSPER4 1.7557 | KCNA1 1.7305 | CACNG6 1.6930 | KCNJ3 1.6361 | TRPC4 1.6274 | KCNB1 1.6104 | CACNA1I 1.6100 | TRPC5 1.6072 | SCN10A 1.5853 | SCN7A 1.5790 | KCNN4 1.5095 | SNAP25 1.4539 | KCNA6 1.4115 | CACNA1S 1.3954 | KCNJ16 1.3936 | SCN3A 1.3785 | KCNJ14 1.3766 | CACNG2 1.3692 | ATP2A1 1.3612 | KCNA10 1.3288 | SCN1B 1.3219 | FKBP1B 1.3101 | PPM1A 1.3037 | KCNG3 1.2978 | KCNJ1 1.2945 | KCND2 1.2892 | KCNE1L 1.2837 | KCNG2 1.2727 | CACNG8 1.2699 | KCNG4 1.2667 | CNTNAP1 1.2662 | LRRC26 1.2637 | KCNQ2 1.2247 | SCN4B 1.2124 | KCNK2 1.1962 | KCNK6 1.1799 | CACNB1 1.1775 | KCNV1 1.1761 | KCNS1 1.1656 | KCNS2 1.1460 | KCNJ8 1.1442 | KCNF1 1.1068 | KCNH4 1.0789 | KCNU1 1.0750 | KCNMB1 1.0743 | KCNV2 1.0713 | CATSPER3 1.0602 | SCN2B 1.0517 | KCNS3 1.0343 | KCNG1 0.9673 | CACNA1F 0.9583 | HSPA2 0.9003 | CNGA4 0.8741 | SCN4A 0.8170 | KCNC3 0.8056 | CACNB3 0.7536 | KCNA3 0.7220 | CATSPER2 0.6702 | KCNA4 0.6180 | PPP2R4 0.6040 | KCND1 0.5914 | KCNJ13 0.4431 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lipid homeostasis (boxplot) | 75 | 78 | 3.764080962113118 | 8.35813613534464E-5 | 0.007425064210417076 | 0.0 | SIRT1 7.4176 | ABCA1 5.6064 | CAV1 3.7656 | ANGPTL4 3.7320 | MLXIPL 3.3990 | SOAT1 3.1809 | APOA1 3.0248 | APOC3 | PTCHD2 2.7324 | SCARB1 2.6205 | APOA4 2.5911 | APOA5 2.5911 | NPC1L1 2.4288 | NR5A2 2.3961 | CAV3 2.3881 | COL4A3BP 2.2085 | ACSM2A 2.2013 | NCOR1 2.1739 | LRP5 2.1685 | LCAT 2.1598 | APOM 2.1586 | ABCG1 2.0741 | EHD1 2.0670 | GPIHBP1 2.0087 | INS 1.9742 | LPL 1.9485 | LYST 1.9420 | LDLR 1.9157 | ASGR2 1.9033 | USF2 1.8819 | PRKAA2 1.8703 | ALMS1 1.8311 | IRS2 1.8084 | PLA2G10 1.7764 | NPC2 1.7277 | DGAT1 1.7111 | HNF4A 1.7052 | MYLIP 1.6924 | PPARG 1.6692 | TMEM97 1.6556 | FITM2 1.6446 | CETP 1.6214 | LIPC 1.6053 | FBXW7 1.5194 | ABCG5 1.4958 | ABCG8 1.4958 | PCSK9 1.4808 | GIP 1.4524 | GOT1 1.4481 | APOE 1.4398 | GPAM 1.4378 | LDLRAP1 1.4279 | DGAT2 1.4198 | ANGPTL3 1.4147 | ABCA2 1.4115 | ACSM1 1.3782 | LAMTOR1 1.3465 | APOC2 1.3441 | APOC4 | NR1H3 1.3265 | LIPG 1.3223 | FABP4 1.3200 | CYP7A1 1.3148 | APOB 1.2451 | MTTP 1.2284 | GCKR 1.2247 | ACSM3 1.1389 | AKR1C1 1.0665 | NPC1 0.9459 | APOA2 0.8951 | ACACA 0.8142 | SOAT2 0.7990 | PRKAA1 0.7726 | PEX2 0.6819 | G6PC 0.6297 | MALL 0.6023 | USF1 0.5700 | CD24 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basement membrane (boxplot) | 89 | 89 | 3.758643290194294 | 8.541859582267275E-5 | 0.007452772485528197 | 0.0 | COL15A1 3.8816 | FBLN1 3.1193 | VEGFA 3.0488 | ADAMTS1 2.9721 | TINAG 2.9207 | LAMA3 2.9086 | COL4A2 2.8351 | COLQ 2.7875 | EGFL6 2.6408 | FREM1 2.6344 | COL4A1 2.5872 | FREM2 2.5468 | VWA1 2.5308 | THBS2 2.4552 | ACAN 2.4524 | MMRN2 2.4359 | LEPREL1 2.3687 | HMCN1 2.3535 | SPARC 2.3530 | LAMA5 2.3426 | FRAS1 2.2991 | COL4A3 2.2501 | LAMA2 2.2226 | CST3 2.1381 | ENTPD2 2.0879 | USH2A 2.0822 | LAMB1 2.0735 | LAMA4 2.0531 | NPNT 2.0460 | NID1 2.0430 | LAMB3 2.0178 | FBN1 1.9663 | LAMC1 1.9271 | TNC 1.9083 | COL5A1 1.9082 | FGF9 1.8959 | LOXL2 1.8848 | ERBB2IP 1.8381 | ALB 1.8309 | LAMC2 1.8307 | RUNX1 1.8302 | VWC2 1.8282 | EGFLAM 1.8194 | ENTPD1 1.7988 | COL28A1 1.7343 | THBS4 1.7325 | LAMA1 1.7275 | SMOC1 1.7156 | COL8A2 1.7125 | NTN4 1.6953 | TGFBI 1.6880 | ANG 1.6605 | COL4A4 1.6590 | LAMB4 1.6528 | AMTN 1.6104 | NID2 1.5906 | SMOC2 1.5879 | CCDC80 1.5762 | TIMP3 1.5753 | SMC3 1.5499 | COL8A1 1.5190 | AGRN 1.5051 | APLP1 1.4983 | LAMB2 1.4979 | COL17A1 1.4533 | COL7A1 1.4181 | CASK 1.4083 | ANXA2 1.4037 | TIMP2 1.3794 | COL4A6 1.3398 | DST 1.3319 | FREM3 1.3229 | COL2A1 1.3191 | COL4A5 1.3070 | HSPG2 1.2964 | RELL2 1.2916 | COL18A1 1.2818 | EFEMP2 1.2636 | SPN 1.2252 | TIMP1 1.2251 | LAD1 1.2243 | NTN1 1.2089 | LAMC3 1.1743 | ITGB1 1.1192 | ACHE 0.9394 | ITGB4 0.8918 | ITGA6 0.8763 | DAG1 0.6937 | ANXA2P2 0.6424 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
protein complex scaffold (boxplot) | 45 | 45 | 3.7573076488855857 | 8.587564671314052E-5 | 0.007452772485528197 | 0.0 | CAV1 3.7656 | MAGI2 3.4637 | MAP2K2 3.3627 | SHANK1 3.1256 | CHCHD3 3.0118 | AKAP6 2.7555 | SMARCD1 2.7351 | AKAP1 2.5165 | CAV3 2.3881 | SHANK2 2.3841 | DLG5 2.3420 | MAPK8IP1 2.3164 | HOMER2 2.3096 | SEPT2 2.2728 | GRIP1 2.2692 | MPP7 2.2168 | CD3E 2.1205 | CD3G 2.1205 | HCN2 2.0858 | SH3RF1 2.0775 | SHANK3 2.0446 | ITSN1 2.0433 | RGS14 1.9785 | AXIN1 1.9756 | ROPN1B 1.9089 | MAPK8IP2 1.8627 | DLG1 1.8617 | MAPK8IP3 1.7605 | EIF3B 1.7481 | CAPN3 1.5788 | CARD10 1.5279 | ARRB2 1.4934 | NCK2 1.4470 | LDLRAP1 1.4279 | ISCU 1.2317 | AKAP7 1.2143 | DEDD2 1.2130 | NUP62 1.1930 | KLHL17 1.1909 | MMS19 1.1470 | AKAP11 1.1450 | BAZ1B 1.0715 | G3BP2 0.9507 | DUSP19 0.8851 | NCK1 0.7460 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
immune response-activating signal transduction (boxplot) | 195 | 207 | 3.7443482750090586 | 9.04313156258052E-5 | 0.0076180587611669685 | 0.0 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | BTK 4.4391 | FYN 3.7055 | MAP2K6 3.6149 | MAP2K2 3.3627 | PSEN2 3.3139 | COLEC12 3.2855 | TBK1 3.1786 | INPP5D 3.1650 | MAPK9 3.1472 | MAP3K7 3.1402 | CARD11 3.1018 | MAP2K7 3.0946 | SPG21 3.0724 | IRF3 3.0381 | PRKCB 2.9939 | NFATC2 2.9629 | TNIP1 2.8951 | LAT 2.8728 | TLR1 2.8628 | TLR6 2.8628 | THEMIS 2.7728 | MICB 2.7706 | PRKCE 2.7354 | CD19 2.7102 | RPS6KA1 2.6847 | TEC 2.6652 | LIME1 2.6410 | ATF1 2.6336 | HLA-DMB 2.6120 | PIK3CD 2.5941 | TXK 2.5595 | KLRK1 2.5472 | IKBKE 2.5138 | RPS6KA2 2.5126 | RBCK1 2.4349 | PLCG2 2.4205 | SKAP1 2.4173 | HLA-DQA1 2.3613 | NFKBIA 2.3376 | DUSP4 2.2855 | IKBKG 2.2420 | KLHL6 2.2407 | MICA 2.1925 | BCL2 2.1766 | MAPK8 2.1614 | RPS27A 2.1523 | HLA-DRB1 2.1516 | NFKBIB 2.1358 | CD3D 2.1205 | CD3E 2.1205 | CD3G | MARCO 2.1156 | SYK 2.1149 | RIPK1 2.0686 | MAPK10 2.0583 | MEF2C 2.0426 | CD4 2.0421 | MAP3K1 1.9924 | IRAK3 1.9617 | DDX58 1.9596 | IRAK4 1.9582 | MAPK1 1.9571 | CD86 1.9313 | TNIP2 1.9162 | PAG1 1.9087 | PELI1 1.8946 | JUN 1.8868 | ENAH 1.8839 | MAPK3 1.8628 | NFKB2 1.8566 | CD38 1.8553 | MAPK7 1.8453 | VAV3 1.8406 | PIK3R1 1.8351 | IRF7 1.8319 | HLA-DRB5 1.8305 | PELI2 1.8302 | MAP2K4 1.8266 | TICAM2 1.7984 | DUSP6 1.7811 | MYD88 1.7773 | HLA-DQB1 1.7437 | GRAP2 1.7178 | IRAK2 1.7090 | PAK2 1.7086 | ATF2 1.7025 | ELK1 1.6910 | TAB2 1.6659 | RELA 1.6587 | TIRAP 1.6414 | BCAR1 1.6063 | LYN 1.5986 | TLR5 1.5927 | HSPD1 1.5925 | HLA-DOB 1.5897 | RPS6KA5 1.5702 | GATA3 1.5648 | TLR7 1.5479 | MAP2K1 1.5376 | HLA-DQA2 1.5353 | HLA-DQB2 | FOXP3 1.5343 | TAB3 1.5206 | ADAM8 1.5178 | UNC93B1 1.5133 | PRKCQ 1.5129 | FOS 1.5019 | HLA-DPA1 1.4883 | HLA-DPB1 | MEF2A 1.4880 | HCK 1.4790 | NFKB1 1.4613 | RIPK2 1.4586 | PDPK1 1.4292 | PTPN22 1.4217 | PTPRC 1.4182 | DMBT1 1.4123 | CLEC7A 1.3986 | ZAP70 1.3847 | PTEN 1.3846 | RPS6KA3 1.3752 | SH2B2 1.3733 | DUSP3 1.3729 | TLR2 1.3663 | LAT2 1.3653 | VASP 1.3560 | SLA2 1.3387 | MALT1 1.3374 | PIK3CA 1.3325 | UBC 1.3324 | LCK 1.3129 | S100A14 1.3048 | IFIH1 1.2976 | UBA52 1.2944 | RNF31 1.2821 | HLA-DRA 1.2787 | CD247 1.2624 | NCKAP1L 1.2593 | PIK3R2 1.2583 | CR2 1.2526 | HLA-DRB3 1.2503 | TLR10 1.2480 | CDK1 1.2389 | UBE2V1 1.2308 | PLEKHA1 1.2069 | C3AR1 1.2032 | CASP8 1.1822 | DUSP7 1.1820 | CHUK 1.1789 | PLCG1 1.1759 | TRAF3 1.1702 | PAK1 1.1424 | TAB1 1.1406 | CARD9 1.1237 | FYB 1.1186 | MNDA 1.1179 | MAPKAPK2 1.1133 | WAS 1.1123 | TRAF6 1.1053 | IRAK1 1.0945 | CSK 1.0827 | ITK 1.0826 | GPLD1 1.0747 | LY96 1.0675 | TLR3 1.0443 | CTLA4 1.0433 | BLK 1.0417 | PSEN1 1.0274 | CYLD 1.0066 | NOD1 1.0056 | TNIP3 0.9864 | TLR4 0.9855 | MAPK14 0.9700 | LCP2 0.9459 | PIK3CB 0.9249 | TNFAIP3 0.9209 | TICAM1 0.9140 | FCER1G 0.8951 | CD79A 0.8908 | MAPKAPK3 0.8717 | MAPK11 0.8399 | TRAT1 0.8232 | BCL10 0.8189 | NFAM1 0.7992 | CACNB3 0.7536 | IKBKB 0.7521 | UBB 0.7504 | NCK1 0.7460 | UBE2N 0.7395 | NOD2 0.6871 | TRIL 0.6826 | ITCH 0.6286 | THY1 0.6002 | PRKD2 0.5986 | MAP2K3 0.5826 | CREB1 0.5390 | BGR | HLA-DRB4 | P01737 | P04436 | TCRA | TCRB | TRAC | TRBC1 | TRBV12-3 |
striated muscle cell differentiation (boxplot) | 135 | 138 | 3.7426538449727045 | 9.104349167965431E-5 | 0.0076180587611669685 | 0.0 | GPHN 5.9364 | RXRB 4.6854 | MYPN 3.2513 | ERBB2 3.2295 | TCAP | ADAM12 3.1898 | VEGFA 3.0488 | ANKRD1 2.9349 | PROX1 2.8868 | SIK1 2.8664 | CAV2 2.8160 | NEBL 2.7784 | SLC8A1 2.7718 | CHAT 2.7603 | T 2.7408 | FHL2 2.6776 | HRAS 2.6539 | TBX3 2.6289 | MUSK 2.5943 | COL4A1 2.5872 | KCNH1 2.5742 | CACNA1H 2.4410 | TTN 2.4386 | FOXP1 2.3270 | CDON 2.3231 | NOS1 2.3035 | CHRNB1 2.2963 | MYH11 2.2753 | AGT 2.2659 | NKX2-5 2.2385 | MYO18B 2.2179 | CACNB2 2.2123 | HOMER1 2.1943 | CXADR 2.1888 | NRG1 2.1819 | SKI 2.1799 | DNER 2.1720 | LRP4 2.1606 | CALR 2.1592 | ACTB 2.1337 | APP 2.1303 | AKT1 2.1144 | MYOZ1 2.0827 | PDZRN3 2.0541 | XIRP1 2.0504 | MEF2C 2.0426 | WNT1 2.0180 | WNT10B | CBY1 1.9948 | TBX5 1.9756 | IGF2 1.9742 | GATA4 1.9478 | MYBPC3 1.9461 | TNC 1.9083 | ACTG1 1.9056 | GPX1 1.8947 | AFG3L2 1.8657 | MYOCD 1.8480 | RCAN1 1.8416 | BARX2 1.8319 | MYH6 1.8142 | TDGF1 1.8065 | TMOD1 1.7664 | RXRA 1.7596 | LEF1 1.7470 | MYLK3 1.7219 | MYEF2 1.6778 | PDGFRA 1.6489 | NKX2-6 1.6263 | IGF1 1.6014 | TPM1 1.5971 | MYOG 1.5902 | CAPN3 1.5788 | LRRK2 1.5730 | KRT19 1.5729 | NEURL2 1.5580 | RYR1 1.5561 | MYL2 1.5502 | GATA6 1.5382 | KIAA1161 1.5218 | NPHS1 1.4983 | MYH10 1.4980 | LAMB2 1.4979 | MEF2A 1.4880 | WT1 1.4801 | DICER1 1.4798 | F2R 1.4291 | PPP3CA 1.4235 | DNAJA3 1.4206 | CACNA1S 1.3954 | CAPN2 1.3921 | CACNG2 1.3692 | IGFBP5 1.3648 | CACYBP 1.3633 | ALS2 1.3539 | TSC1 1.3322 | ATG5 1.3205 | CHRNA1 1.3109 | COL4A5 1.3070 | MYOD1 1.2690 | DVL1 1.2676 | SHH 1.2438 | CDK1 1.2389 | PDGFRB 1.2307 | TNNT2 1.2243 | DOK7 1.2147 | TDGF1P3 1.2115 | RB1 1.1822 | SRF 1.1778 | MTPN 1.1615 | OBSL1 1.1569 | MYH9 1.1496 | MET 1.1441 | BMP10 1.1425 | SORT1 1.1418 | ATG7 1.1390 | ITGB1 1.1192 | BMP4 1.1081 | ACTC1 1.1031 | DYRK1B 1.1007 | MYLK2 1.0997 | LMNA 1.0722 | LEMD2 1.0653 | ACVR1 1.0582 | SDC1 1.0557 | NRD1 1.0284 | RARA 1.0131 | MESP1 1.0064 | KRAS 0.9975 | ACTA1 0.9736 | NRAS 0.9279 | ACADM 0.9259 | PTCD2 0.9115 | HEY2 0.8433 | AVPR1A 0.6808 | SNTA1 0.5644 | CCNB1 0.5640 | HNTN1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
neuron cell-cell adhesion (boxplot) | 12 | 12 | 3.70663742634537 | 1.050146450362055E-4 | 0.008551692594115002 | 0.0 | CNTN4 4.2048 | NRXN1 3.6097 | TNR 3.0413 | NLGN1 2.7866 | NCAM2 2.4471 | CTNND2 2.4273 | ASTN1 2.3129 | NINJ2 2.0112 | RET 1.9319 | NLGN3 1.5936 | CDK5R1 0.9094 | NLGN2 0.6604 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organic ether metabolic process (boxplot) | 119 | 119 | 3.700180479199095 | 1.0772309506601463E-4 | 0.008628443319549959 | 0.0 | SIRT1 7.4176 | LPIN2 5.2136 | TXNL1 3.9971 | PDIA5 3.7819 | CAV1 3.7656 | FAR2 3.4933 | AGMO 3.1160 | APOC3 3.0248 | LPCAT1 3.0227 | ELOVL6 2.9754 | PRKACB 2.9293 | GPD1 2.7351 | ACLY 2.7017 | PPP1CB 2.6090 | APOA5 2.5911 | AGPAT4 2.5633 | ABHD5 2.5629 | CDIPT 2.5282 | TXNDC2 2.5233 | GPAT2 2.5064 | ELOVL2 2.4805 | MOGAT3 2.4686 | CAV3 2.3881 | PCK1 2.3007 | ACSL1 2.2283 | SLC27A5 2.1872 | LCLAT1 2.1535 | LPIN1 2.1486 | ELOVL1 2.0817 | ACSL5 2.0627 | AGPAT6 2.0214 | AGPAT2 2.0126 | PLCE1 2.0072 | SLC22A4 1.9862 | TMX3 1.9767 | PDIA2 1.9756 | LPL 1.9485 | DGKK 1.9475 | TXNDC5 1.9456 | ELOVL7 1.9273 | CYP19A1 1.9264 | MOGAT1 1.9020 | GPX1 1.8947 | ALMS1 1.8311 | AGPS 1.8230 | CCL5 1.8122 | CPS1 1.8058 | SLC25A1 1.8029 | PNPLA2 1.7743 | PRKACG 1.7616 | AGPAT3 1.7230 | GK 1.7138 | DGAT1 1.7111 | PEX7 1.6864 | ACSL6 1.6845 | ANG 1.6605 | PDIA6 1.6347 | AGPAT5 1.6333 | LIPF 1.6322 | PNPLA3 1.6241 | TXNDC8 1.6232 | CETP 1.6214 | ACSL3 1.6086 | LIPC 1.6053 | CDS2 1.6034 | AGPAT1 1.5913 | DGKD 1.5653 | NKX2-3 1.5542 | HSD17B12 1.5489 | PDIA4 1.5403 | CYP11A1 1.5384 | FAR1 1.5101 | TXN 1.5088 | TECR 1.5086 | TXN2 1.5012 | PNLIPRP2 1.4930 | PCSK9 1.4808 | MGLL 1.4752 | APOE 1.4398 | GPAM 1.4378 | DGAT2 1.4198 | CYP2E1 1.3837 | PLIN1 1.3583 | APOC1 1.3441 | TMEM86B 1.3238 | FABP4 1.3200 | PPP1CA 1.3052 | ACSL4 1.2837 | CYP1A1 1.2677 | APOB 1.2451 | APOH 1.2376 | MTTP 1.2284 | GNPAT 1.2058 | LIPE 1.1888 | FASN 1.1849 | CPT1A 1.1834 | CEL 1.1461 | CYP17A1 1.1376 | ELOVL4 1.1167 | PGS1 1.1094 | INSIG2 1.0701 | GPD1L 1.0398 | PPP1CC 1.0164 | CDS1 1.0042 | MOGAT2 0.9999 | QSOX1 0.9486 | APOA2 0.8951 | ELOVL5 0.8407 | ACACA 0.8142 | DNAJC10 0.8057 | CYP1A2 0.7604 | PRKACA 0.6979 | PDIA3 0.6933 | CAT 0.6876 | AGPAT9 0.6685 | INSIG1 0.6516 | P4HB 0.6423 | ELOVL3 0.6419 | G6PC 0.6297 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
calcium ion transmembrane transporter activity (boxplot) | 108 | 109 | 3.6931200035741134 | 1.1075971176377486E-4 | 0.008728579865771031 | 0.0 | PDE2A 3.7330 | RYR2 3.1737 | GRIN3A 3.1467 | CACNB4 3.1376 | ATP2C2 3.1033 | CUL5 3.0470 | CACNA1G 3.0242 | RASA3 2.9238 | CACNA1C 2.8754 | ATP2B2 2.8342 | GRM7 2.8268 | SLC8A1 2.7718 | TRPM7 2.7626 | CACNG3 2.6709 | RYR3 2.5711 | TPCN2 2.5016 | SLC24A3 2.4609 | CACNA1H 2.4410 | TRPM3 2.4127 | TRPM8 2.3742 | GPM6A 2.3326 | ATP2B4 2.2998 | GRIN2B 2.2951 | CACNG4 2.2546 | CACNB2 2.2123 | TRPV1 2.1980 | JPH3 2.1788 | ITPR2 2.1594 | CACNA1D 2.1182 | CACNA1E 2.0970 | GRIN2A 2.0931 | CHRNA10 2.0484 | TRPV4 2.0262 | CACNA2D1 1.9982 | PKD2 1.9879 | GAS6 1.9676 | CACNA2D3 1.9648 | CYTH3 1.9639 | CACNG7 1.9540 | P2RX1 1.9501 | CACNA1A 1.9305 | HTR2B 1.9303 | SLC24A2 1.9291 | TRPM4 1.9153 | SLC8A3 1.9072 | CATSPER1 1.8550 | CACNA1B 1.8481 | TMEM37 1.8371 | TRPM1 1.8355 | CACNG1 1.8336 | TPCN1 1.7668 | SLC24A1 1.7667 | ITPR3 1.7657 | CATSPER4 1.7557 | TRPC7 1.7543 | ITGAV 1.7509 | ATP2B3 1.7173 | TRPV3 1.7121 | CACNA2D2 1.6959 | CACNG6 1.6930 | ATP2A2 1.6834 | CACNG5 1.6745 | PANX1 1.6650 | TRPM2 1.6363 | REST 1.6316 | TRPC4 1.6274 | CACNA1I 1.6100 | TRPC5 1.6072 | MCU 1.6010 | RYR1 1.5561 | TRPA1 1.5544 | ATP2C1 1.5260 | CHRNA9 1.5108 | SLC8A2 1.4933 | TRPV5 1.4897 | ITPR1 1.4342 | TRPC6 1.4311 | CACNA2D4 1.4192 | MS4A2 1.4184 | SLC3A2 1.4035 | CACNA1S 1.3954 | FKBP1A 1.3770 | CACNG2 1.3692 | ATP2A1 1.3612 | TRPC3 1.3214 | FKBP1B 1.3101 | SLC11A2 1.3019 | CACNG8 1.2699 | GRIN1 1.2637 | CACNB1 1.1775 | TRPV2 1.1404 | JPH2 1.1317 | FGF2 1.1278 | TRPM6 1.0811 | GRIN3B 1.0627 | CATSPER3 1.0602 | CLCA3P 1.0301 | PSEN1 1.0274 | CACFD1 1.0115 | ATP2A3 0.9855 | TRPC1 0.9629 | CACNA1F 0.9583 | ATP2B1 0.9361 | CACNB3 0.7536 | CALHM1 0.6965 | CATSPER2 0.6702 | TRPV6 0.5852 | ORAI1 0.5808 | SCL8A3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
dendrite development (boxplot) | 56 | 56 | 3.6930591145154135 | 1.1078624544680338E-4 | 0.008728579865771031 | 0.0 | PICALM 3.8576 | FAS 3.2882 | SCARF1 3.2573 | GRIN3A 3.1467 | SHANK1 3.1256 | DAB1 2.9720 | CHAT 2.7603 | LST1 2.7317 | EPHB2 2.7088 | EPHB1 2.6334 | IGSF9 2.6039 | DSCAM 2.5746 | SRGAP2 2.5232 | PRKG1 2.4878 | MCF2 2.4868 | DCLK1 2.3698 | CTNNA2 2.3669 | MAP1B 2.2447 | RELN 2.2249 | EPHA5 2.1737 | APP 2.1303 | SHANK3 2.0446 | TULP1 1.9365 | CACNA1A 1.9305 | KLF7 1.9081 | STRN 1.8799 | DCX 1.8681 | MAPK8IP2 1.8627 | FEZF2 1.7876 | ABI2 1.7385 | DLG4 1.7370 | SDC2 1.6349 | BMP7 1.5842 | ATP7A 1.5814 | CDK5 1.5715 | BBS4 1.5605 | CELSR2 1.5268 | MEF2A 1.4880 | TRAPPC4 1.4783 | MINK1 1.4611 | KLHL1 1.4546 | SS18L1 1.4460 | PTEN 1.3846 | SLC11A2 1.3019 | ACSL4 1.2837 | DVL1 1.2676 | BDNF 1.2240 | SYNGAP1 1.1743 | PAK1 1.1424 | MAP2 1.0970 | GHRL 0.9974 | CACNA1F 0.9583 | HDAC2 0.9044 | PAK3 0.8800 | HPRT1 0.8115 | EPHB3 0.6149 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Ras guanyl-nucleotide exchange factor activity (boxplot) | 92 | 93 | 3.6862531778712344 | 1.137899762553296E-4 | 0.008728579865771031 | 0.0 | RAPGEF5 4.5256 | ARHGEF10 3.8915 | SPATA13 3.6908 | KALRN 3.6105 | PLEKHG2 3.4715 | PLEKHG1 3.2405 | PREX1 2.9502 | RASGRF1 2.9288 | ARHGEF3 2.8881 | AKAP13 2.8539 | TIAM1 2.8400 | RGNEF 2.6947 | RASGEF1B 2.6211 | MCF2 2.4868 | RASGRF2 2.4633 | TIAM2 2.4489 | FGD2 2.4194 | FARP1 2.2734 | FARP2 2.2728 | RIN2 2.2598 | RGL1 2.2583 | KNDC1 2.2520 | DOCK2 2.2237 | MCF2L2 2.2166 | ARHGEF18 2.2107 | ARHGEF38 2.2024 | PREX2 2.2018 | ITSN2 2.1500 | TRIO 2.1284 | ARHGEF9 2.0887 | FGD4 2.0673 | ARHGEF5 2.0614 | ARHGEF11 2.0462 | ITSN1 2.0433 | DOCK11 2.0111 | FGD5 1.9928 | VAV2 1.9727 | PLEKHG7 1.9482 | MADD 1.9461 | OBSCN 1.9276 | SERGEF 1.8772 | RGL2 1.8466 | VAV3 1.8406 | ABR 1.7595 | DOCK10 1.7553 | RAPGEF4 1.6971 | ALS2CL 1.6454 | ARHGEF4 1.6452 | RAPGEF2 1.6242 | ARHGEF37 1.6201 | PLEKHG5 1.5723 | ARHGEF16 1.5691 | PLEKHG6 1.5603 | MCF2L 1.5518 | FGD6 1.5470 | ECT2L 1.5269 | SOS2 1.5227 | RASGRP4 1.4810 | FGD3 1.4630 | RAB3IL1 1.4391 | NET1 1.4291 | ARHGEF26 1.4139 | ARHGEF10L 1.4113 | FGD1 1.4085 | ARHGEF40 1.3953 | VAV1 1.3902 | BCR 1.3878 | ALS2 1.3539 | RANBP10 1.3283 | RASGRP3 1.3202 | RCBTB2 1.3141 | NGEF 1.3111 | ARHGEF15 1.2884 | ARHGEF12 1.2882 | C9orf100 1.1946 | DNMBP 1.1537 | SOS1 1.1496 | ARHGEF25 1.1372 | ARHGEF7 1.1278 | ARHGEF33 1.0894 | ARHGEF2 1.0873 | RGL3 1.0733 | PLEKHG4B 1.0721 | RASGEF1A 0.9575 | ARHGEF19 0.9428 | ARHGEF17 0.9078 | ARHGEF1 0.8908 | PLEKHG3 0.8754 | ARHGEF6 0.6228 | ECT2 0.5904 | PLEKHG4 0.4639 | RCC1 0.1854 | RP11-114F7.3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ligand-gated ion channel activity (boxplot) | 134 | 137 | 3.683050449914618 | 1.1522976379230165E-4 | 0.008728579865771031 | 0.0 | GRID1 5.7829 | KCNJ12 5.2371 | GRIK4 3.9399 | GABRG3 3.6968 | GRIA4 3.3765 | GRIK2 3.2889 | KCNJ4 3.2311 | RYR2 3.1737 | GRIN3A 3.1467 | KCNJ5 3.0325 | GRID2 3.0003 | GABRB3 2.9924 | KCNQ5 2.9323 | RASA3 2.9238 | HTR3B 2.8560 | ASIC2 2.7474 | GABRR3 2.6005 | PEX5L 2.5959 | GLRA2 2.5894 | RYR3 2.5711 | CNGB1 2.5546 | CNGB3 2.5426 | ASIC5 2.5107 | TPCN2 2.5016 | GABRA3 2.4286 | GRIA3 2.4068 | SCNN1B 2.4026 | HTR3E 2.3683 | HTR3C 2.3466 | P2RX5 2.3388 | CHRNB1 2.2963 | GRIN2B 2.2951 | KCNH7 2.2610 | GABRG1 2.2106 | JPH3 2.1788 | ITPR2 2.1594 | SHROOM2 2.1572 | GRIN2A 2.0931 | GABRA5 2.0812 | CHRNA10 2.0484 | KCNJ6 2.0282 | HTR3D 2.0080 | GRIK3 2.0041 | GABRQ 1.9995 | PKD2 1.9879 | GRIN2C 1.9757 | CYTH3 1.9639 | P2RX1 1.9501 | CLCA2 1.9393 | P2RX7 1.8574 | ASIC1 1.8572 | CHRNA2 1.8484 | KCNK1 1.8306 | GRIK1 1.8243 | KCNH2 1.8168 | CNGA2 1.8158 | GABRG2 1.8133 | SCNN1D 1.8009 | TPCN1 1.7668 | ITPR3 1.7657 | GRIK5 1.7636 | CHRND 1.7516 | AQP1 1.7153 | GABRR1 1.7119 | GABRB2 1.7081 | CHRNA7 1.6719 | GABRB1 1.6717 | GLRA3 1.6714 | KCNJ3 1.6361 | TRPC4 1.6274 | TRPC5 1.6072 | ZACN 1.5950 | GABRA1 1.5731 | ASIC3 1.5715 | HCN4 1.5579 | RYR1 1.5561 | CHRNA9 1.5108 | P2RX4 1.5095 | CHRNG 1.4825 | CHRNE 1.4611 | GLRA1 1.4443 | ITPR1 1.4342 | TRPC6 1.4311 | KCNJ16 1.3936 | SCNN1A 1.3929 | P2RX3 1.3783 | FKBP1A 1.3770 | CFTR 1.3770 | GRIN2D 1.3766 | KCNJ14 1.3766 | SCNN1G 1.3430 | KCNA10 1.3288 | TRPC3 1.3214 | CHRNA1 1.3109 | FKBP1B 1.3101 | KCNJ1 1.2945 | GABRD 1.2730 | GRIN1 1.2637 | GABRP 1.2409 | GABRA2 1.2072 | GLRA4 1.2033 | CHRNA4 1.2001 | CHRNA3 1.1921 | CHRNB4 | GLRB 1.1896 | KCNK6 1.1799 | HTR3A 1.1787 | GABRE 1.1782 | KCNJ11 1.1557 | CHRNA5 1.1534 | GRIA1 1.1475 | KCNJ8 1.1442 | JPH2 1.1317 | CNGA3 1.1275 | KCNJ2 1.0875 | GRIN3B 1.0627 | KCNJ15 1.0099 | TRPC1 0.9629 | GRIA2 0.9514 | CHRNB2 0.9425 | GABRR2 0.8946 | CNGA4 0.8741 | GABRA6 0.8703 | KCNJ10 0.8338 | P2RX6 0.7959 | GABRA4 0.7578 | P2RX2 0.6514 | ORAI1 0.5808 | STX1B 0.5451 | KCNH6 0.5251 | KCNJ9 0.4817 | KCNJ18 0.4591 | KCNJ13 0.4431 | CHRNA6 0.3958 | CHRNB3 0.3372 | CHRFAM7A | CHRNA7-2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ligand-gated channel activity (boxplot) | 134 | 137 | 3.683050449914618 | 1.1522976379230165E-4 | 0.008728579865771031 | 0.0 | GRID1 5.7829 | KCNJ12 5.2371 | GRIK4 3.9399 | GABRG3 3.6968 | GRIA4 3.3765 | GRIK2 3.2889 | KCNJ4 3.2311 | RYR2 3.1737 | GRIN3A 3.1467 | KCNJ5 3.0325 | GRID2 3.0003 | GABRB3 2.9924 | KCNQ5 2.9323 | RASA3 2.9238 | HTR3B 2.8560 | ASIC2 2.7474 | GABRR3 2.6005 | PEX5L 2.5959 | GLRA2 2.5894 | RYR3 2.5711 | CNGB1 2.5546 | CNGB3 2.5426 | ASIC5 2.5107 | TPCN2 2.5016 | GABRA3 2.4286 | GRIA3 2.4068 | SCNN1B 2.4026 | HTR3E 2.3683 | HTR3C 2.3466 | P2RX5 2.3388 | CHRNB1 2.2963 | GRIN2B 2.2951 | KCNH7 2.2610 | GABRG1 2.2106 | JPH3 2.1788 | ITPR2 2.1594 | SHROOM2 2.1572 | GRIN2A 2.0931 | GABRA5 2.0812 | CHRNA10 2.0484 | KCNJ6 2.0282 | HTR3D 2.0080 | GRIK3 2.0041 | GABRQ 1.9995 | PKD2 1.9879 | GRIN2C 1.9757 | CYTH3 1.9639 | P2RX1 1.9501 | CLCA2 1.9393 | P2RX7 1.8574 | ASIC1 1.8572 | CHRNA2 1.8484 | KCNK1 1.8306 | GRIK1 1.8243 | KCNH2 1.8168 | CNGA2 1.8158 | GABRG2 1.8133 | SCNN1D 1.8009 | TPCN1 1.7668 | ITPR3 1.7657 | GRIK5 1.7636 | CHRND 1.7516 | AQP1 1.7153 | GABRR1 1.7119 | GABRB2 1.7081 | CHRNA7 1.6719 | GABRB1 1.6717 | GLRA3 1.6714 | KCNJ3 1.6361 | TRPC4 1.6274 | TRPC5 1.6072 | ZACN 1.5950 | GABRA1 1.5731 | ASIC3 1.5715 | HCN4 1.5579 | RYR1 1.5561 | CHRNA9 1.5108 | P2RX4 1.5095 | CHRNG 1.4825 | CHRNE 1.4611 | GLRA1 1.4443 | ITPR1 1.4342 | TRPC6 1.4311 | KCNJ16 1.3936 | SCNN1A 1.3929 | P2RX3 1.3783 | FKBP1A 1.3770 | CFTR 1.3770 | GRIN2D 1.3766 | KCNJ14 1.3766 | SCNN1G 1.3430 | KCNA10 1.3288 | TRPC3 1.3214 | CHRNA1 1.3109 | FKBP1B 1.3101 | KCNJ1 1.2945 | GABRD 1.2730 | GRIN1 1.2637 | GABRP 1.2409 | GABRA2 1.2072 | GLRA4 1.2033 | CHRNA4 1.2001 | CHRNA3 1.1921 | CHRNB4 | GLRB 1.1896 | KCNK6 1.1799 | HTR3A 1.1787 | GABRE 1.1782 | KCNJ11 1.1557 | CHRNA5 1.1534 | GRIA1 1.1475 | KCNJ8 1.1442 | JPH2 1.1317 | CNGA3 1.1275 | KCNJ2 1.0875 | GRIN3B 1.0627 | KCNJ15 1.0099 | TRPC1 0.9629 | GRIA2 0.9514 | CHRNB2 0.9425 | GABRR2 0.8946 | CNGA4 0.8741 | GABRA6 0.8703 | KCNJ10 0.8338 | P2RX6 0.7959 | GABRA4 0.7578 | P2RX2 0.6514 | ORAI1 0.5808 | STX1B 0.5451 | KCNH6 0.5251 | KCNJ9 0.4817 | KCNJ18 0.4591 | KCNJ13 0.4431 | CHRNA6 0.3958 | CHRNB3 0.3372 | CHRFAM7A | CHRNA7-2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
peptidyl-tyrosine modification (boxplot) | 62 | 66 | 3.668717054257304 | 1.2188534209256474E-4 | 0.008888534051705541 | 0.0 | PRLR 4.7596 | BTK 4.4391 | FYN 3.7055 | ERBB4 3.2809 | JAK1 3.1693 | INSR 3.1624 | GHR 3.1211 | FES 3.1088 | FLT3 2.7949 | FGFR2 2.7650 | EPHB2 2.7088 | FLT1 2.6297 | EPHA1 2.5465 | EFEMP1 2.4217 | TPST2 2.3300 | RELN 2.2249 | EGF 2.1937 | ABI1 2.1356 | SYK 2.1149 | CLK1 2.0672 | FER 1.8987 | JAK3 1.8666 | TEK 1.8630 | IL12RB1 1.8501 | CLK4 1.7615 | ABL2 1.7537 | ABI2 1.7385 | EPHA4 1.6721 | PDGFRA 1.6489 | DDR1 1.6458 | WEE1 1.6421 | DYRK1A 1.6138 | LYN 1.5986 | FGFR1 1.5730 | KDR 1.5543 | STAT5A 1.5114 | LIF 1.4805 | OSM | HCK 1.4790 | IL12RB2 1.4711 | FGFR3 1.4587 | ABL1 1.4403 | F2R 1.4291 | KIT 1.4147 | LEP 1.4143 | JAK2 1.4043 | TPST1 1.3967 | PTK2 1.3822 | LCK 1.3129 | FLT4 1.2760 | CSF1R 1.2307 | PDGFRB 1.2307 | ABI3 1.2170 | DDR2 1.1922 | FGR 1.1781 | PTPN6 1.1681 | CLK2 1.1605 | PTK6 1.1515 | FGFR4 1.1354 | PTK2B 1.1280 | PDGFB 1.0240 | PXN 1.0115 | CLK3 0.3891 | DKFZp686A20267 | MNB | DYRK | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
social behavior (boxplot) | 34 | 35 | 3.66326791638982 | 1.2450892024085114E-4 | 0.008946332122011746 | 0.0 | NRXN1 3.6097 | NPAS3 3.5151 | SHANK1 3.1256 | ANXA7 2.9900 | DNAJC9 2.9727 | NR2E1 2.8955 | HRAS 2.6539 | MSS51 2.4174 | PPP3CB 2.4174 | OXTR 2.3881 | NLGN4X 2.3043 | SLC6A4 2.2725 | SHANK3 2.0446 | HTT 2.0106 | TH 1.9742 | DRD3 1.9435 | AVP 1.9195 | OXT | IL1B 1.8813 | TBX1 1.8661 | MAPK8IP2 1.8627 | DRD4 1.8319 | GNB1L 1.8155 | DBH 1.8135 | DLG4 1.7370 | NLGN3 1.5936 | MKKS 1.5151 | CLN8 1.4407 | PTEN 1.3846 | DVL1 1.2676 | GRPR 1.2039 | VPS13A 1.0804 | KRAS 0.9975 | CHRNB2 0.9425 | AVPR1A 0.6808 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
learning or memory (boxplot) | 148 | 148 | 3.6512728037799334 | 1.304719397290377E-4 | 0.009238926050957654 | 0.0 | AMFR 3.9690 | FYN 3.7055 | NRXN1 3.6097 | AMPH 3.4482 | PARK2 3.3357 | PSEN2 3.3139 | NTF4 3.2839 | FOXP2 3.2196 | SHANK1 3.1256 | TNR 3.0413 | RASGRF1 2.9288 | GRM7 2.8268 | NTRK2 2.7766 | CHAT 2.7603 | EPHB2 2.7088 | HRAS 2.6539 | PLCB1 2.6151 | NETO1 2.5980 | MUSK 2.5943 | COMT 2.5550 | CAMK4 2.5094 | SLC12A5 2.5026 | PLK2 2.4876 | CTNND2 2.4273 | PPP3CB 2.4174 | SERPINF1 2.4022 | OXTR 2.3881 | GRIN2B 2.2951 | CNTN2 2.2820 | SLC6A4 2.2725 | SGK1 2.2618 | GLP1R 2.2306 | JPH3 2.1788 | HMGCR 2.1730 | PRKAR1B 2.1387 | APP 2.1303 | ARC 2.1147 | CACNA1E 2.0970 | GRIN2A 2.0931 | TMOD2 2.0922 | ATXN1 2.0856 | GABRA5 2.0812 | SHANK3 2.0446 | NGF 2.0438 | MEF2C 2.0426 | HTT 2.0106 | ATAD1 2.0096 | PTGS2 1.9806 | RGS14 1.9785 | GRM5 1.9765 | TH 1.9742 | PRKCG 1.9540 | ITGA8 1.9537 | DRD3 1.9435 | SLC24A2 1.9291 | OXT 1.9195 | EGR2 1.8938 | JUN 1.8868 | IL1B 1.8813 | MAPK8IP2 1.8627 | DRD4 1.8319 | DBH 1.8135 | NEUROD2 1.8013 | PPP1R1B 1.8013 | PPT1 1.7921 | GRM4 1.7819 | PRKAR2B 1.7791 | SLC17A7 1.7655 | ADCY1 1.7392 | ABI2 1.7385 | DLG4 1.7370 | TANC1 1.7362 | CYP7B1 1.7230 | PTN 1.7220 | ADCY8 1.7139 | CHRNA7 1.6719 | HIF1A 1.6618 | AFF2 1.6538 | CHST10 1.6519 | VLDLR 1.6091 | TAC1 1.6069 | CNR1 1.6061 | ADRB1 1.6047 | NLGN3 1.5936 | DRD2 1.5853 | HTR2A 1.5850 | CDK5 1.5715 | ADNP 1.5371 | FOXP3 1.5343 | STRA6 1.5142 | FOXB1 1.5142 | FOS 1.5019 | GALR2 1.4880 | ADRA1B 1.4817 | DRD1 1.4777 | SLC6A1 1.4647 | SNAP25 1.4539 | CLN8 1.4407 | SHC3 1.4335 | CALB1 1.4175 | KLK8 1.4015 | PTEN 1.3846 | CRHR1 1.3545 | TACR1 1.3533 | VDAC1 1.3400 | BTG2 1.3309 | ITGA3 1.3270 | CLN3 1.3063 | SLC11A2 1.3019 | DRD5 1.2989 | NF1 1.2913 | GRIN1 1.2637 | MDK 1.2489 | STS 1.2284 | RPS6KB1 1.2260 | BDNF 1.2240 | GRPR 1.2039 | GM2A 1.1879 | ATP1A3 1.1872 | PDE1B 1.1847 | SRF 1.1778 | SYNGAP1 1.1743 | FOSL1 1.1638 | AAAS 1.1523 | GRIA1 1.1475 | BCHE 1.1249 | PDE5A 1.1185 | CRHBP 1.0855 | THRA 1.0727 | FZD9 1.0715 | PSEN1 1.0274 | PJA2 1.0179 | KRAS 0.9975 | S100B 0.9943 | CHRNB2 0.9425 | NRAS 0.9279 | ADAM2 0.9271 | MAN2B1 0.9100 | GALR3 0.8839 | ITGA5 0.8380 | CRH 0.8287 | UCN 0.8158 | PAFAH1B1 0.8148 | RIC8A 0.6441 | SYNJ1 0.6101 | EGR1 0.5440 | ATP1A2 0.4943 | NTAN1 0.4376 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
main axon (boxplot) | 33 | 33 | 3.6386319180360274 | 1.3704510929368752E-4 | 0.009565748628699388 | 0.0 | SCN2A 3.6519 | MYO1D 3.2744 | DLG2 3.2580 | CNTNAP2 3.1556 | MBP 3.0687 | ROBO2 3.0085 | NFASC 2.9513 | SPOCK1 2.7896 | BIN1 2.3168 | CNTN2 2.2820 | TUBB4A 2.2033 | ROBO1 2.1673 | SCN8A 2.1612 | GABBR1 1.9622 | KCNAB2 1.9081 | MAG 1.8819 | KCNA2 1.8775 | DLG1 1.8617 | UCN3 1.8448 | DBH 1.8135 | SLC1A2 1.7777 | MAPK8IP3 1.7605 | DLG4 1.7370 | KCNA1 1.7305 | ADORA1 1.7070 | ADORA2A 1.3027 | CNTNAP1 1.2662 | CDH1 1.2150 | CRHBP 1.0855 | ERMN 1.0218 | CCK 0.9390 | KCNC3 0.8056 | DAG1 0.6937 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
presynaptic membrane (boxplot) | 47 | 47 | 3.6366927710038053 | 1.380804941486513E-4 | 0.009565748628699388 | 0.0 | GRIK4 3.9399 | PICALM 3.8576 | PDE2A 3.7330 | NRXN1 3.6097 | ERC2 3.3555 | GRIK2 3.2889 | GRM8 3.2143 | GRM7 2.8268 | SYT1 2.6792 | KCTD16 2.6397 | SNAP91 2.4483 | NPTN 2.3588 | GRIN2B 2.2951 | UNC13C 2.2620 | ERC1 2.2200 | CAMK2A 2.1496 | SNCAIP 2.1411 | GRIN2A 2.0931 | RIMS1 1.9395 | SCRIB 1.9095 | GRIK1 1.8243 | SEPT3 1.7964 | SLC1A2 1.7777 | ADORA1 1.7070 | ZNRF2 1.6826 | UNC13A 1.6800 | KCTD8 1.6688 | GRM1 1.6533 | RIMS2 1.5957 | FBXO45 1.5364 | LRRC4B 1.4908 | CASK 1.4083 | PICK1 1.3992 | LRFN3 1.3681 | DENND1A 1.3576 | GRM3 1.3280 | ADORA2A 1.3027 | KCTD12 1.2705 | FOSL1 1.1638 | GRM2 1.0960 | PCDH8 1.0462 | GRIA2 0.9514 | ACHE 0.9394 | GAD2 0.8924 | GABRA6 0.8703 | SYP 0.8425 | L1CAM 0.6002 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
DNA synthesis involved in DNA repair (boxplot) | 10 | 10 | 3.625794148753814 | 1.4403738636326047E-4 | 0.009774537080151259 | 0.0 | SIRT1 7.4176 | POLA1 6.3131 | POLH 1.6146 | RFC3 1.6016 | POLD3 1.2925 | WRN 1.2667 | POLD1 1.1632 | WRNIP1 1.0872 | POLE 1.0804 | CDKN2D 0.9929 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
peptidyl-tyrosine phosphorylation (boxplot) | 60 | 64 | 3.6201966951428584 | 1.471895731954831E-4 | 0.009851619926481238 | 0.0 | PRLR 4.7596 | BTK 4.4391 | FYN 3.7055 | ERBB4 3.2809 | JAK1 3.1693 | INSR 3.1624 | GHR 3.1211 | FES 3.1088 | FLT3 2.7949 | FGFR2 2.7650 | EPHB2 2.7088 | FLT1 2.6297 | EPHA1 2.5465 | EFEMP1 2.4217 | RELN 2.2249 | EGF 2.1937 | ABI1 2.1356 | SYK 2.1149 | CLK1 2.0672 | FER 1.8987 | JAK3 1.8666 | TEK 1.8630 | IL12RB1 1.8501 | CLK4 1.7615 | ABL2 1.7537 | ABI2 1.7385 | EPHA4 1.6721 | PDGFRA 1.6489 | DDR1 1.6458 | WEE1 1.6421 | DYRK1A 1.6138 | LYN 1.5986 | FGFR1 1.5730 | KDR 1.5543 | STAT5A 1.5114 | LIF 1.4805 | OSM | HCK 1.4790 | IL12RB2 1.4711 | FGFR3 1.4587 | ABL1 1.4403 | F2R 1.4291 | KIT 1.4147 | LEP 1.4143 | JAK2 1.4043 | PTK2 1.3822 | LCK 1.3129 | FLT4 1.2760 | CSF1R 1.2307 | PDGFRB 1.2307 | ABI3 1.2170 | DDR2 1.1922 | FGR 1.1781 | PTPN6 1.1681 | CLK2 1.1605 | PTK6 1.1515 | FGFR4 1.1354 | PTK2B 1.1280 | PDGFB 1.0240 | PXN 1.0115 | CLK3 0.3891 | DKFZp686A20267 | MNB | DYRK | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of fatty acid metabolic process (boxplot) | 66 | 69 | 3.6125039107425265 | 1.516272658504958E-4 | 0.010011497580344898 | 0.0 | SIRT1 7.4176 | CAV1 3.7656 | PRKAG2 3.7137 | FABP1 3.5813 | MLXIPL 3.3990 | C1QTNF2 3.0733 | APOC3 3.0248 | APOA4 2.5911 | APOA5 2.5911 | UGT1A7 2.5865 | UGT1A8 2.5865 | UGT1A9 | PPARGC1A 2.4496 | TRIB3 2.4349 | ACACB 2.4178 | PLA2G4A 2.3298 | AGT 2.2659 | ACSL1 2.2283 | CAB39L 2.1178 | AKT1 2.1144 | TWIST1 2.0979 | SNCA 1.9846 | PTGS2 1.9806 | INS 1.9742 | AVP 1.9195 | IRS1 1.9115 | MID1IP1 1.8925 | CPT1B 1.8780 | PRKAA2 1.8703 | SREBF1 1.8466 | SCAP 1.8227 | IRS2 1.8084 | ANXA1 1.8032 | AKT2 1.7769 | MTOR 1.7516 | GHSR 1.7166 | BRCA1 1.7066 | HNF4A 1.7052 | PPARG 1.6692 | ABCD2 1.6687 | TYSND1 1.6177 | CNR1 1.6061 | CPT2 1.5335 | CAB39 1.5334 | APOC1 1.3441 | APOC2 | ADIPOQ 1.3289 | NR1H3 1.3265 | LONP2 1.3144 | ACADVL 1.2681 | ACADL 1.2388 | CPT1A 1.1834 | STRADB 1.1749 | STK11 1.1724 | NR1H2 1.1632 | PRKAG1 1.1069 | PRKAB2 1.0760 | INSIG2 1.0701 | PRKAG3 1.0632 | PRKAB1 1.0322 | PPARA 1.0266 | STRADA 0.9421 | MLYCD 0.8198 | EIF2AK3 0.7800 | PRKAA1 0.7726 | SLC25A20 0.7171 | AVPR1A 0.6808 | INSIG1 0.6516 | FRAP1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
collagen (boxplot) | 92 | 94 | 3.6038917984766057 | 1.5674380173491542E-4 | 0.010211336203690623 | 0.0 | EMILIN2 4.7716 | COL11A2 4.6854 | COL10A1 4.5846 | COL15A1 3.8816 | COLEC12 3.2855 | C1QA 3.1690 | C1QB | C1QC | C1QTNF2 3.0733 | COL23A1 2.9611 | CCBE1 2.9199 | COL4A2 2.8351 | COLQ 2.7875 | COL13A1 2.7836 | COL6A2 2.7393 | COL4A1 2.5872 | COLEC11 2.4495 | COL19A1 2.3157 | COL25A1 2.3088 | SCARA3 2.2803 | COL6A5 2.2733 | C1QTNF6 2.2634 | COL4A3 2.2501 | COL27A1 2.2485 | COL12A1 2.2318 | COL14A1 2.1863 | COL24A1 2.1417 | TNXB 2.1180 | COL6A1 2.1167 | MARCO 2.1156 | SFTPD 1.9782 | COL9A1 1.9621 | COL5A1 1.9082 | COL22A1 1.8769 | COL6A3 1.8501 | COLEC10 1.8182 | C1QTNF1 1.8054 | COL9A3 1.7829 | P4HA3 1.7785 | LUM 1.7679 | FCN1 1.7436 | COL28A1 1.7343 | COL8A2 1.7125 | SERPINH1 1.6958 | COL6A6 1.6842 | COL4A4 1.6590 | EDA 1.6572 | MMP2 1.6530 | C1QTNF8 1.6457 | C1QTNF5 1.5942 | EMID2 1.5941 | PLOD1 1.5622 | COL21A1 1.5421 | COL16A1 1.5390 | COL8A1 1.5190 | FCN3 1.5004 | COL1A1 1.4835 | CTHRC1 1.4804 | COL3A1 1.4690 | MMP13 1.4661 | COL17A1 1.4533 | COL5A2 1.4504 | COL11A1 1.4339 | COL7A1 1.4181 | COL1A2 1.4123 | C1QTNF9 1.3838 | FCN2 1.3678 | COL5A3 1.3492 | COL4A6 1.3398 | COL9A2 1.3311 | ADIPOQ 1.3289 | COL2A1 1.3191 | C1QL2 1.3164 | COL4A5 1.3070 | GLDN 1.3027 | COL18A1 1.2818 | EMID1 1.2776 | MSR1 1.2705 | LOX 1.2677 | C1QL1 1.1839 | C1QL3 1.1803 | SFTPA2 1.1240 | MBL2 1.1098 | WDR33 1.0905 | DCN 1.0126 | C1QTNF9B 0.9871 | OTOL1 0.9528 | COL20A1 0.8836 | EMILIN1 0.8762 | C1QTNF7 0.7801 | PLOD2 0.7720 | C1QTNF3 0.7577 | SFTPA1 0.7503 | C1QL4 0.4197 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of synaptic transmission (boxplot) | 44 | 44 | 3.5779802677909602 | 1.731297924674191E-4 | 0.011130423236786969 | 0.0 | NRXN1 3.6097 | GRIA4 3.3765 | GRIK2 3.2889 | ERBB4 3.2809 | TNF 3.0639 | TNR 3.0413 | NR2E1 2.8955 | NLGN1 2.7866 | PRKCE 2.7354 | PLK2 2.4876 | OXTR 2.3881 | NPTN 2.3588 | GRIN2B 2.2951 | RELN 2.2249 | LAMA2 2.2226 | SLC1A3 2.1895 | SHANK3 2.0446 | SNCA 1.9846 | PTGS2 1.9806 | RGS14 1.9785 | SLC24A2 1.9291 | OXT 1.9195 | GRIK1 1.8243 | PRKCZ 1.7929 | DLG4 1.7370 | KISS1R 1.7173 | SERPINE2 1.6272 | TAC1 1.6069 | NLGN3 1.5936 | ARRB2 1.4934 | DRD1 1.4777 | GIP 1.4524 | LGI1 1.4430 | CRHR1 1.3545 | TACR1 1.3533 | CCKBR 1.3511 | ADORA2A 1.3027 | GFAP 1.2059 | PINK1 1.1846 | CHRNB2 0.9425 | NMU 0.8991 | IFNG 0.8931 | CCL2 0.6763 | NLGN2 0.6604 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of fatty acid biosynthetic process (boxplot) | 27 | 28 | 3.577298443066509 | 1.735818628665342E-4 | 0.011130423236786969 | 0.0 | SIRT1 7.4176 | PRKAG2 3.7137 | MLXIPL 3.3990 | APOC3 3.0248 | APOA4 2.5911 | APOA5 2.5911 | TRIB3 2.4349 | PLA2G4A 2.3298 | AGT 2.2659 | PTGS2 1.9806 | AVP 1.9195 | MID1IP1 1.8925 | PRKAA2 1.8703 | SCAP 1.8227 | ANXA1 1.8032 | BRCA1 1.7066 | HNF4A 1.7052 | APOC1 1.3441 | APOC2 | NR1H3 1.3265 | ACADVL 1.2681 | ACADL 1.2388 | STK11 1.1724 | NR1H2 1.1632 | PRKAB2 1.0760 | INSIG2 1.0701 | AVPR1A 0.6808 | INSIG1 0.6516 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
p53 binding (boxplot) | 46 | 47 | 3.57357209826996 | 1.7607211180781235E-4 | 0.011130423236786969 | 0.0 | SIRT1 7.4176 | CDKN2AIP 4.0035 | TP63 3.0850 | CDKN2A 3.0353 | RNF20 2.9604 | ANKRD1 2.9349 | BANP 2.8836 | EHMT2 2.7933 | SMARCA4 2.7826 | USP10 2.6326 | KDM1A 2.5909 | SETD7 2.2483 | TP53BP1 2.2102 | TP73 2.1456 | MAPKAPK5 2.1048 | EHMT1 2.0962 | TAF9 2.0572 | HTT 2.0106 | AXIN1 1.9756 | BLM 1.8278 | DAXX 1.8243 | MUC1 1.8194 | SMARCB1 1.8190 | CREBBP 1.7131 | TAF3 1.7066 | SETD8 1.6968 | TAF1 1.6628 | RCHY1 1.6184 | HSPD1 1.5925 | CDK5 1.5715 | MSX1 1.4876 | SMYD2 1.4219 | USP7 1.4191 | TP53 1.3523 | BRD7 1.3186 | GSK3B 1.1968 | STK11 1.1724 | PLK3 1.1387 | NUAK1 1.1328 | TRIM24 1.0739 | RFWD3 0.8330 | CHD8 0.8015 | MDM2 0.7327 | PSME3 0.7018 | TP53RK 0.4324 | GATA1 0.1162 | mdm2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
development of primary female sexual characteristics (boxplot) | 101 | 104 | 3.571828747793609 | 1.7724859883416766E-4 | 0.011130423236786969 | 0.0 | SIRT1 7.4176 | PCYT1B 7.2283 | TIPARP 3.3907 | ARID5B 3.1718 | FANCA 3.1547 | TP63 3.0850 | SOHLH1 3.0802 | VEGFA 3.0488 | ROBO2 3.0085 | AMH 2.9749 | ADAMTS1 2.9721 | SLIT2 2.8500 | DACH2 2.8064 | CHAT 2.7603 | TBX3 2.6289 | FGF7 2.5131 | ADCYAP1R1 2.5080 | IQCJ-SCHIP1 2.4652 | SLIT3 2.4489 | MSH4 2.4326 | FSHR 2.4105 | FST 2.4000 | SCHIP1 2.3967 | VGF 2.3948 | PLA2G4A 2.3298 | AGT 2.2659 | RBP4 2.2565 | SRD5A1 2.1992 | NRIP1 2.1803 | BCL2 2.1766 | CCND2 2.1625 | ACSBG1 2.1597 | FOXL2 2.1573 | FOXO3 2.0675 | WNT10B 2.0180 | IMMP2L 1.9821 | MMP14 1.9618 | ZFP42 1.9444 | DMC1 1.9224 | BMPR1B 1.9013 | NR5A1 1.8809 | EDN2 1.8797 | ESR1 1.8508 | ESR2 1.8459 | AFP 1.7611 | LHCGR 1.7607 | EIF2B4 1.7419 | CAPN5 1.7012 | STRA8 1.6857 | ICAM1 1.6718 | ANG 1.6605 | PDGFRA 1.6489 | NOS3 1.6288 | INHBA 1.6220 | KDR 1.5543 | MMP19 1.5508 | STRA6 1.5142 | STAT5A 1.5114 | FANCG 1.4995 | CASP2 1.4160 | LEP 1.4143 | KITLG 1.3781 | CTNNA1 1.3657 | BMP15 1.3595 | NOBOX 1.3482 | SFRP1 1.2842 | UBE3A 1.2776 | BRCA2 1.2712 | TAF4 1.2681 | EIF2B5 1.2665 | PGR 1.2410 | FSHB 1.2331 | FOXC1 1.2136 | PLEKHA1 1.2069 | LHX9 1.1994 | LFNG 1.1848 | ANGPT1 1.1416 | INHBB 1.1310 | ERMP1 1.1105 | BMP4 1.1081 | ADRBK1 1.0662 | CHD7 1.0210 | STAT5B 1.0063 | GPR149 0.9780 | WNT4 0.9772 | INHA 0.8631 | SOD1 0.8543 | SGPL1 0.8268 | WNT10A 0.8239 | BCL2L1 0.8053 | EREG 0.8038 | NKX2-1 0.7775 | ACVR1B 0.7753 | FZD4 0.7448 | FGF10 0.7055 | SPO11 0.6482 | AHR 0.6079 | CENPI 0.4883 | CCNE1 0.4397 | EIF2B2 0.2862 | KGFLP2 0.1912 | A6NF36 | KGFLP1 | estrogen receptor | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stress fiber (boxplot) | 44 | 44 | 3.5705326645131445 | 1.7812801117123023E-4 | 0.011130423236786969 | 0.0 | MYO1C 4.9972 | SEPT7 4.3221 | MYLK 3.2871 | SEPT11 3.2438 | SYNPO 2.9309 | NEBL 2.7784 | ZYX 2.5465 | SEPT9 2.5051 | TPM3 2.4781 | PDLIM2 2.3613 | FHOD1 2.2999 | DLC1 2.2963 | MYH11 2.2753 | AMOT 2.2199 | LIMA1 2.0815 | ACTN1 2.0386 | GAS2L2 1.9360 | ENAH 1.8839 | TEK 1.8630 | SEPT12 1.8144 | MYH6 1.8142 | MYH7 1.8142 | MYL9 1.7057 | PGM5 1.7013 | FSCN1 1.6954 | SORBS1 1.6523 | GAS2L1 1.6509 | TPM1 1.5971 | MYL12B 1.5886 | MYH10 1.4980 | FERMT2 1.4965 | DAAM1 1.4884 | ACTN4 1.4437 | PDLIM7 1.3736 | SH2B2 1.3733 | TPM4 1.3177 | CNN2 1.2907 | MST1R 1.2550 | MYH9 1.1496 | ILK 1.1347 | FHL3 0.9837 | ACTA1 0.9736 | SHROOM4 0.9493 | FBLIM1 0.5285 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cholesterol homeostasis (boxplot) | 52 | 54 | 3.5619083698371807 | 1.8408444442585825E-4 | 0.011130423236786969 | 0.0 | SIRT1 7.4176 | ABCA1 5.6064 | CAV1 3.7656 | SOAT1 3.1809 | APOA1 3.0248 | APOC3 | PTCHD2 2.7324 | SCARB1 2.6205 | APOA4 2.5911 | APOA5 2.5911 | NPC1L1 2.4288 | NR5A2 2.3961 | CAV3 2.3881 | NCOR1 2.1739 | LRP5 2.1685 | LCAT 2.1598 | APOM 2.1586 | ABCG1 2.0741 | EHD1 2.0670 | GPIHBP1 2.0087 | LDLR 1.9157 | ALMS1 1.8311 | PLA2G10 1.7764 | NPC2 1.7277 | MYLIP 1.6924 | TMEM97 1.6556 | CETP 1.6214 | LIPC 1.6053 | ABCG5 1.4958 | ABCG8 1.4958 | PCSK9 1.4808 | APOE 1.4398 | LDLRAP1 1.4279 | DGAT2 1.4198 | ANGPTL3 1.4147 | ABCA2 1.4115 | ACSM1 1.3782 | LAMTOR1 1.3465 | APOC2 1.3441 | NR1H3 1.3265 | LIPG 1.3223 | FABP4 1.3200 | CYP7A1 1.3148 | APOB 1.2451 | MTTP 1.2284 | ACSM3 1.1389 | AKR1C1 1.0665 | NPC1 0.9459 | APOA2 0.8951 | SOAT2 0.7990 | PEX2 0.6819 | G6PC 0.6297 | MALL 0.6023 | CD24 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sterol homeostasis (boxplot) | 52 | 54 | 3.5619083698371807 | 1.8408444442585825E-4 | 0.011130423236786969 | 0.0 | SIRT1 7.4176 | ABCA1 5.6064 | CAV1 3.7656 | SOAT1 3.1809 | APOA1 3.0248 | APOC3 | PTCHD2 2.7324 | SCARB1 2.6205 | APOA4 2.5911 | APOA5 2.5911 | NPC1L1 2.4288 | NR5A2 2.3961 | CAV3 2.3881 | NCOR1 2.1739 | LRP5 2.1685 | LCAT 2.1598 | APOM 2.1586 | ABCG1 2.0741 | EHD1 2.0670 | GPIHBP1 2.0087 | LDLR 1.9157 | ALMS1 1.8311 | PLA2G10 1.7764 | NPC2 1.7277 | MYLIP 1.6924 | TMEM97 1.6556 | CETP 1.6214 | LIPC 1.6053 | ABCG5 1.4958 | ABCG8 1.4958 | PCSK9 1.4808 | APOE 1.4398 | LDLRAP1 1.4279 | DGAT2 1.4198 | ANGPTL3 1.4147 | ABCA2 1.4115 | ACSM1 1.3782 | LAMTOR1 1.3465 | APOC2 1.3441 | NR1H3 1.3265 | LIPG 1.3223 | FABP4 1.3200 | CYP7A1 1.3148 | APOB 1.2451 | MTTP 1.2284 | ACSM3 1.1389 | AKR1C1 1.0665 | NPC1 0.9459 | APOA2 0.8951 | SOAT2 0.7990 | PEX2 0.6819 | G6PC 0.6297 | MALL 0.6023 | CD24 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cellular response to insulin stimulus (boxplot) | 190 | 192 | 3.560647511207162 | 1.8497070894030188E-4 | 0.011130423236786969 | 0.0 | ATP6V1D 5.0589 | CRK 4.9972 | FGF19 4.0340 | PRKAG2 3.7137 | GRB2 3.5564 | EIF4G1 3.5399 | INPP5K 3.5378 | MAP2K2 3.3627 | INSR 3.1624 | PHIP 3.1621 | HDAC9 3.1337 | GHR 3.1211 | ATP6V1G2 3.0639 | PRKDC 2.8038 | BAIAP2 2.7979 | FGFR2 2.7650 | HRAS 2.6539 | PPAT 2.6276 | RPTOR 2.5941 | TLR9 2.5867 | APOBEC1 2.5650 | STXBP4 2.5613 | SIK2 2.5468 | FRS2 2.5419 | KAT2B 2.5358 | SLC29A2 2.5230 | AKAP1 2.5165 | FGF7 2.5131 | TRIB3 2.4349 | ATP6V0D1 2.4205 | IGF1R 2.4090 | FGF17 2.4040 | ATP6V1C1 2.3669 | IDE 2.3580 | DLC1 2.2963 | FBP1 2.2674 | FGF1 2.2613 | GCK 2.2586 | FGF23 2.2484 | FGF22 2.2464 | SRD5A1 2.1992 | HMGCS2 2.1809 | CCND2 2.1625 | LPIN1 2.1486 | ATP6V1B1 2.1332 | GAB1 2.1327 | CAB39L 2.1178 | AKT1 2.1144 | PTPN11 2.0897 | FOXO3 2.0675 | ACSL5 2.0627 | GRB10 2.0523 | EIF4B 2.0361 | PTPRA 2.0157 | FGF4 2.0087 | PIK3R3 2.0057 | ATP6V0D2 1.9877 | ATP6V0A2 1.9809 | IGF2 1.9742 | INS | MAPK1 1.9571 | IRS1 1.9115 | FER 1.8987 | FGF9 1.8959 | ATP6V1G1 1.8891 | PRKAA2 1.8703 | MAPK3 1.8628 | SREBF1 1.8466 | AHSG 1.8397 | PARP1 1.8367 | PIK3R1 1.8351 | IRS2 1.8084 | FGF8 1.7956 | ATP6V0A1 1.7946 | FOXO4 1.7940 | PTPN2 1.7929 | AKT2 1.7769 | ATP6V0E2 1.7632 | RXRA 1.7596 | MTOR 1.7516 | SHC2 1.7321 | EIF4EBP2 1.7274 | KL 1.7172 | GHSR 1.7166 | RAF1 1.7090 | PDE3B 1.7081 | FGF18 1.7053 | ATP6V1E1 1.6865 | PPARG 1.6692 | HIF1A 1.6618 | GHRHR 1.6541 | SORBS1 1.6523 | ATP6V0A4 1.6520 | ALDOB 1.6449 | SMARCC1 1.6448 | SLC2A8 1.6424 | ZFP106 1.6400 | ATP6V1C2 1.6347 | VLDLR 1.6091 | BCAR1 1.6063 | FGF5 1.6008 | EIF4EBP1 1.6002 | EEF2K 1.5954 | ATP6V1F 1.5869 | FGF3 1.5781 | SLC2A4 1.5730 | FGFR1 1.5730 | MLST8 1.5439 | MAP2K1 1.5376 | CAB39 1.5334 | ATP6V1H 1.5286 | ATP6V1E2 1.5221 | TCIRG1 1.5133 | PCSK9 1.4808 | DRD1 1.4777 | HDAC5 1.4726 | FGFR3 1.4587 | ATP6V1B2 1.4506 | GOT1 1.4481 | GRB14 1.4400 | GPAM 1.4378 | ATP6V0B 1.4365 | SHC3 1.4335 | PDPK1 1.4292 | SELS 1.4224 | PTPN1 1.4205 | FOXC2 1.4158 | THEM4 1.3903 | SH2B2 1.3733 | KLB 1.3538 | ATP6V0E1 1.3495 | PIK3CA 1.3325 | TSC1 1.3322 | ADIPOQ 1.3289 | NR1H3 1.3265 | AP3S1 1.3252 | PPM1A 1.3037 | SHC1 1.2933 | PIK3R2 1.2583 | FGF20 1.2458 | CDK1 1.2389 | RPS6KB1 1.2260 | GSK3A 1.2130 | ENPP1 1.1901 | STRADB 1.1749 | FOXS1 1.1734 | STK11 1.1724 | SOS1 1.1496 | RHOQ 1.1486 | PAK1 1.1424 | FGFR4 1.1354 | ATP6V0C 1.1317 | INHBB 1.1310 | FGF2 1.1278 | PRKAG1 1.1069 | APPL1 1.1065 | PRKAB2 1.0760 | GPLD1 1.0747 | TSC2 1.0731 | PRKAG3 1.0632 | ATP6V1A 1.0601 | ERBB3 1.0409 | YWHAB 1.0405 | PIK3R4 1.0348 | PRKAB1 1.0322 | FGF16 1.0317 | IGFBP1 0.9990 | KRAS 0.9975 | FGF6 0.9927 | UCP2 0.9897 | CAPN10 0.9884 | RHEB 0.9858 | SOCS7 0.9852 | DOK1 0.9629 | PRKCI 0.9445 | STRADA 0.9421 | NRAS 0.9279 | PIK3CB 0.9249 | PIK3C2A 0.8669 | PKLR 0.8529 | FOXO1 0.8294 | NAMPT 0.8179 | EIF4E 0.7883 | PRKAA1 0.7726 | PIK3C3 0.7608 | FGF10 0.7055 | ATP6V1G3 0.6241 | UBE2B 0.6043 | USF1 0.5700 | PLA2G1B 0.4953 | RPS6 0.3423 | FOXO6 | |||||||||||||||
regulation of developmental growth (boxplot) | 94 | 95 | 3.5580821247906926 | 1.8678626194790215E-4 | 0.011130423236786969 | 0.0 | DCC 5.1066 | NTRK3 4.8124 | NIPBL 3.6793 | ERBB4 3.2809 | SLIT1 3.2641 | INSR 3.1624 | TNR 3.0413 | CDH4 3.0350 | CARM1 2.8879 | PROX1 2.8868 | FGFR2 2.7650 | BASP1 2.7554 | MSTN 2.6651 | PLCB1 2.6151 | MUSK 2.5943 | DSCAM 2.5746 | CXCL12 2.5696 | MT3 2.3391 | BCL11A 2.3352 | FOXP1 2.3270 | RTN4 2.3237 | TNFRSF12A 2.3109 | RBP4 2.2565 | MAP1B 2.2447 | NKX2-5 2.2385 | POR 2.2319 | CXADR 2.1888 | NRG1 2.1819 | SPP1 2.1654 | FXN 2.1599 | WNT3 2.0876 | TWF2 2.0553 | NGF 2.0438 | MEF2C 2.0426 | SAV1 2.0321 | ISLR2 2.0308 | WNT10B 2.0180 | HNF1B 1.9806 | TBX5 1.9756 | GATA4 1.9478 | RNF6 1.9069 | FGF9 1.8959 | ANAPC2 1.7859 | DUSP6 1.7811 | ZP3 1.7758 | HOPX 1.7405 | RYK 1.6892 | SEMA3A 1.6808 | WNT3A 1.6407 | ADRB1 1.6047 | CAPN3 1.5788 | WNT2 1.5764 | FGFR1 1.5730 | NDEL1 1.5703 | GATA6 1.5382 | ADNP 1.5371 | NRCAM 1.5362 | AGRN 1.5051 | EP300 1.4888 | WT1 1.4801 | FGFR3 1.4587 | APOE 1.4398 | LEP 1.4143 | SEMA4D 1.3860 | WNT5A 1.3655 | MYOD1 1.2690 | FGF20 1.2458 | CDK1 1.2389 | SEMA3F 1.2271 | RPS6KB1 1.2260 | SEMA4F 1.2167 | GSK3A 1.2130 | NTN1 1.2089 | LIMK1 1.1825 | BMP10 1.1425 | TRPV2 1.1404 | ILK 1.1347 | FGF2 1.1278 | BARHL2 1.1224 | BMP4 1.1081 | ADRB2 1.0467 | CDKL5 1.0190 | ULK1 0.9247 | HEY2 0.8433 | AR 0.8277 | PAFAH1B1 0.8148 | SIX1 0.8071 | OMG 0.7849 | SEMA7A 0.7223 | NOG 0.6617 | CCNB1 0.5640 | SIX4 0.4859 | TTL 0.4819 | MAPT 0.4387 | DKFZp434G0625 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cell recognition (boxplot) | 67 | 70 | 3.5537767164501375 | 1.898707345997508E-4 | 0.011130423236786969 | 0.0 | CNTN4 4.2048 | VCAN 3.6291 | COLEC12 3.2855 | CNTNAP2 3.1556 | NTM 3.1203 | ROBO2 3.0085 | OPCML 2.8603 | CNTNAP3 2.8037 | EPHA3 2.7107 | EPHB2 2.7088 | SCARB1 2.6205 | DSCAM 2.5746 | CSGALNACT1 2.5188 | NCR3 2.4215 | DSCAML1 2.3591 | LAMA5 2.3426 | RTN4 2.3237 | CCR7 2.3166 | FOXG1 2.2887 | CNTN2 2.2820 | DOCK2 2.2237 | CADM1 2.2215 | PCSK4 2.1754 | ROBO1 2.1673 | APP 2.1303 | PECAM1 2.1136 | PEAR1 2.0418 | MFGE8 2.0138 | FUT3 1.9654 | CD209 1.9282 | CLEC4M | MEGF10 1.8707 | DLG1 1.8617 | FEZF2 1.7876 | ZP3 1.7758 | ST6GALNAC6 1.7677 | CELSR3 1.6843 | SEMA3A 1.6808 | SPA17 1.6759 | EPHA4 1.6721 | ROBO3 1.5671 | CRTAM 1.5477 | NRCAM 1.5362 | CD36 1.4667 | AMIGO1 1.4658 | UBAP2L 1.4095 | CLEC7A 1.3986 | ARSA 1.3806 | NDN 1.3688 | ZAN 1.3533 | EFNB3 1.2849 | PCDH12 1.2795 | ZPBP2 1.2788 | CCL19 1.2605 | CCL21 | BDNF 1.2240 | CD5 1.1624 | DYNLL2 1.1549 | CD226 1.1277 | CLGN 1.1268 | SPACA3 1.1041 | JMJD6 1.0466 | ATP8B3 0.9821 | ZP2 0.9445 | CDK5R1 0.9094 | B4GALT1 0.8108 | ZPBP 0.7574 | EPHB3 0.6149 | SPAM1 0.5353 | BGR | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cognition (boxplot) | 162 | 162 | 3.5523577589000968 | 1.9089768825730768E-4 | 0.011130423236786969 | 0.0 | AMFR 3.9690 | FYN 3.7055 | NIPBL 3.6793 | NRXN1 3.6097 | AMPH 3.4482 | PARK2 3.3357 | PSEN2 3.3139 | NTF4 3.2839 | FOXP2 3.2196 | SHANK1 3.1256 | TNR 3.0413 | RASGRF1 2.9288 | GRM7 2.8268 | NTRK2 2.7766 | CHAT 2.7603 | EPHB2 2.7088 | HRAS 2.6539 | PLCB1 2.6151 | NETO1 2.5980 | MUSK 2.5943 | COMT 2.5550 | CAMK4 2.5094 | SLC12A5 2.5026 | PLK2 2.4876 | CTNND2 2.4273 | PPP3CB 2.4174 | SERPINF1 2.4022 | OXTR 2.3881 | CTNS 2.3388 | GRIN2B 2.2951 | CNTN2 2.2820 | SLC6A4 2.2725 | SGK1 2.2618 | GLP1R 2.2306 | JPH3 2.1788 | HMGCR 2.1730 | PRKAR1B 2.1387 | APP 2.1303 | ARC 2.1147 | CACNA1E 2.0970 | GRIN2A 2.0931 | TMOD2 2.0922 | ATXN1 2.0856 | GABRA5 2.0812 | SHANK3 2.0446 | NGF 2.0438 | MEF2C 2.0426 | HTT 2.0106 | ATAD1 2.0096 | PTGS2 1.9806 | RGS14 1.9785 | GRM5 1.9765 | TH 1.9742 | PRKCG 1.9540 | ITGA8 1.9537 | DRD3 1.9435 | SLC24A2 1.9291 | OXT 1.9195 | EGR2 1.8938 | JUN 1.8868 | IL1B 1.8813 | MAPK8IP2 1.8627 | DRD4 1.8319 | DBH 1.8135 | NEUROD2 1.8013 | PPP1R1B 1.8013 | PPT1 1.7921 | GRM4 1.7819 | PRKAR2B 1.7791 | SLC17A7 1.7655 | ADCY1 1.7392 | ABI2 1.7385 | DLG4 1.7370 | TANC1 1.7362 | CYP7B1 1.7230 | PTN 1.7220 | SLC1A4 1.7165 | ADCY8 1.7139 | TUSC3 1.7094 | ADORA1 1.7070 | CHRNA7 1.6719 | HIF1A 1.6618 | AFF2 1.6538 | CHST10 1.6519 | CHL1 1.6315 | VLDLR 1.6091 | TAC1 1.6069 | CNR1 1.6061 | ADRB1 1.6047 | NLGN3 1.5936 | DRD2 1.5853 | HTR2A 1.5850 | CDK5 1.5715 | BBS4 1.5605 | ADNP 1.5371 | FOXP3 1.5343 | STRA6 1.5142 | FOXB1 1.5142 | FOS 1.5019 | GALR2 1.4880 | ADRA1B 1.4817 | DRD1 1.4777 | SLC6A1 1.4647 | SNAP25 1.4539 | CLN8 1.4407 | SHC3 1.4335 | CALB1 1.4175 | MAGT1 1.4030 | KLK8 1.4015 | PTEN 1.3846 | CRHR1 1.3545 | TACR1 1.3533 | VDAC1 1.3400 | BTG2 1.3309 | ITGA3 1.3270 | CLN3 1.3063 | SLC11A2 1.3019 | DRD5 1.2989 | NF1 1.2913 | GRIN1 1.2637 | MDK 1.2489 | STS 1.2284 | PTCHD1 1.2262 | RPS6KB1 1.2260 | BDNF 1.2240 | HOXA1 1.2096 | GRPR 1.2039 | CHRNA4 1.2001 | GM2A 1.1879 | ATP1A3 1.1872 | PDE1B 1.1847 | SRF 1.1778 | SYNGAP1 1.1743 | FOSL1 1.1638 | AAAS 1.1523 | GRIA1 1.1475 | BCHE 1.1249 | PDE5A 1.1185 | CRHBP 1.0855 | THRA 1.0727 | FZD9 1.0715 | TTC8 1.0556 | PSEN1 1.0274 | CHD7 1.0210 | PJA2 1.0179 | KRAS 0.9975 | S100B 0.9943 | SHROOM4 0.9493 | CHRNB2 0.9425 | NRAS 0.9279 | ADAM2 0.9271 | MAN2B1 0.9100 | GALR3 0.8839 | ITGA5 0.8380 | CRH 0.8287 | UCN 0.8158 | PAFAH1B1 0.8148 | RIC8A 0.6441 | SYNJ1 0.6101 | EGR1 0.5440 | ATP1A2 0.4943 | NTAN1 0.4376 | |||||||||||||||||||||||||||||||||||||||||||||
neuron recognition (boxplot) | 28 | 28 | 3.540392371080193 | 1.997662788500998E-4 | 0.011219057913351581 | 0.0 | CNTN4 4.2048 | CNTNAP2 3.1556 | NTM 3.1203 | ROBO2 3.0085 | OPCML 2.8603 | EPHA3 2.7107 | EPHB2 2.7088 | DSCAM 2.5746 | DSCAML1 2.3591 | RTN4 2.3237 | FOXG1 2.2887 | CNTN2 2.2820 | ROBO1 2.1673 | APP 2.1303 | FEZF2 1.7876 | CELSR3 1.6843 | SEMA3A 1.6808 | EPHA4 1.6721 | ROBO3 1.5671 | NRCAM 1.5362 | AMIGO1 1.4658 | NDN 1.3688 | EFNB3 1.2849 | PCDH12 1.2795 | BDNF 1.2240 | DYNLL2 1.1549 | CDK5R1 0.9094 | EPHB3 0.6149 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
neurotransmitter transport (boxplot) | 97 | 99 | 3.5235866293703193 | 2.1287394759683664E-4 | 0.011819342135887999 | 0.0 | VAMP1 4.1635 | PCLO 4.0360 | ICA1 3.4698 | PARK2 3.3357 | CPLX2 3.2544 | NLGN1 2.7866 | PPFIA3 2.7612 | CHAT 2.7603 | SLC18A3 | STX1A 2.7012 | XBP1 2.6965 | SNPH 2.6851 | SYN2 2.6795 | SYT1 2.6792 | STXBP1 2.6367 | RIMS3 2.6132 | SPTBN2 2.5986 | SLC6A16 2.5905 | CADPS 2.5522 | HRH3 2.5237 | SV2C 2.4442 | SLC6A4 2.2725 | SEPT5 2.2712 | SLC22A2 2.2511 | ARL2 2.2292 | SLC1A3 2.1895 | SV2A 2.1873 | GLS 2.1689 | SLC38A1 2.1315 | SLC18A2 2.0880 | PARK7 2.0872 | SYN3 2.0801 | WNT7A 2.0616 | BAIAP3 2.0183 | SLC17A8 2.0171 | STX3 2.0045 | GABRQ 1.9995 | SNCA 1.9846 | RIMS1 1.9395 | AP2B1 1.9360 | CACNA1A 1.9305 | SLC17A6 1.8970 | UNC13B 1.8915 | SYT4 1.8726 | P2RX7 1.8574 | SLC5A7 1.8496 | CACNA1B 1.8481 | PPT1 1.7921 | GRM4 1.7819 | SLC17A7 1.7655 | SLC6A12 1.7455 | PIP5K1C 1.7353 | BRSK1 1.7013 | CPLX1 1.6807 | UNC13A 1.6800 | DOC2B 1.6682 | OTOF 1.6397 | SLC32A1 1.6305 | SV2B 1.6279 | SLC38A2 1.5792 | CDK5 1.5715 | SLC6A11 1.5526 | DOC2A 1.5395 | CPLX4 1.5355 | GLUL 1.5159 | SYN1 1.4729 | SLC6A1 1.4647 | SNAP25 1.4539 | CLN8 1.4407 | RAB3A 1.4334 | ABAT 1.3792 | SNAPIN 1.3340 | HSPA8 1.2788 | DNAJC5 1.2774 | DVL1 1.2676 | SYT2 1.2635 | GLS2 1.2509 | GABRA2 1.2072 | SLC18A1 1.1645 | SLC22A3 1.1331 | SLC25A4 1.1125 | CPLX3 1.1056 | PLDN 1.1027 | GAD1 1.0859 | ALDH5A1 1.0747 | VAMP2 1.0699 | RIMS4 1.0444 | PSEN1 1.0274 | SLC6A13 1.0084 | GAD2 0.8924 | KCNJ10 0.8338 | RAB14 0.7921 | SLC6A15 0.7607 | STX4 0.6681 | SYNJ1 0.6101 | STX1B 0.5451 | ATP1A2 0.4943 | MAOA 0.3928 | F5H0A2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cell volume homeostasis (boxplot) | 15 | 15 | 3.522181141970859 | 2.1400578959784866E-4 | 0.011819342135887999 | 0.0 | AQP2 4.0312 | KCNMA1 3.3055 | ANXA7 2.9900 | ADD1 2.5292 | SLC12A7 2.4107 | E2F4 2.2999 | SLC12A4 2.1598 | SHANK3 2.0446 | TRPV4 2.0262 | P2RX7 1.8574 | SLC6A12 1.7455 | AQP1 1.7153 | KCNN4 1.5095 | CLNS1A 1.5019 | CLCN6 1.0642 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
guanyl-nucleotide exchange factor activity (boxplot) | 161 | 167 | 3.5215523680618745 | 2.1451395955884855E-4 | 0.011819342135887999 | 0.0 | RAPGEF5 4.5256 | ARHGEF10 3.8915 | SPATA13 3.6908 | KALRN 3.6105 | PLEKHG2 3.4715 | CHRM4 3.3170 | PSD3 3.2638 | PLEKHG1 3.2405 | RALGPS2 3.1519 | PREX1 2.9502 | RASGRF1 2.9288 | BCAR3 2.9072 | ARHGEF3 2.8881 | AKAP13 2.8539 | TIAM1 2.8400 | RGNEF 2.6947 | RAPGEF3 2.6418 | RASGEF1B 2.6211 | CYTH1 2.5051 | MCF2 2.4868 | RASGRF2 2.4633 | TIAM2 2.4489 | DOCK9 2.4472 | RASGRP1 2.4400 | ANKRD27 2.4284 | FGD2 2.4194 | DOCK4 2.3990 | SH2D3C 2.2820 | FARP1 2.2734 | FARP2 2.2728 | RIN2 2.2598 | RGL1 2.2583 | KNDC1 2.2520 | DOCK2 2.2237 | MCF2L2 2.2166 | ARHGEF18 2.2107 | ARHGEF38 2.2024 | PREX2 2.2018 | IQSEC3 2.1987 | ITSN2 2.1500 | ARFGEF2 2.1359 | RALGPS1 2.1285 | TRIO 2.1284 | DENND1C 2.1267 | ARHGEF9 2.0887 | HERC2 2.0776 | FGD4 2.0673 | ARHGEF5 2.0614 | DOCK1 2.0545 | ARHGEF11 2.0462 | ITSN1 2.0433 | DOCK11 2.0111 | IQSEC2 2.0095 | PLCE1 2.0072 | FGD5 1.9928 | VAV2 1.9727 | CYTH3 1.9639 | RIC8B 1.9498 | PLEKHG7 1.9482 | MADD 1.9461 | OBSCN 1.9276 | SERGEF 1.8772 | RAPGEF1 1.8760 | RPGR 1.8677 | GBF1 1.8566 | RGL2 1.8466 | VAV3 1.8406 | KIAA1244 1.8331 | RAPGEF6 1.8198 | FFAR1 1.8156 | IQSEC1 1.7986 | DOCK5 1.7922 | ABR 1.7595 | MON2 1.7574 | DOCK10 1.7553 | EIF2B4 1.7419 | TBXA2R 1.7383 | DOCK6 1.7289 | RAPGEF4 1.6971 | RASGEF1C 1.6849 | ALS2CL 1.6454 | ARHGEF4 1.6452 | RAPGEF2 1.6242 | ARHGEF37 1.6201 | PCP2 1.6054 | DIS3 1.5986 | PSD 1.5878 | PLEKHG5 1.5723 | ARHGEF16 1.5691 | PLEKHG6 1.5603 | MCF2L 1.5518 | FGD6 1.5470 | ECT2L 1.5269 | SOS2 1.5227 | DOCK3 1.5109 | RGL4 1.5025 | FBXO8 1.4936 | RASGRP4 1.4810 | FGD3 1.4630 | RAB3IL1 1.4391 | ARFGEF1 1.4358 | DOCK8 1.4354 | NET1 1.4291 | DOCK7 1.4147 | ARHGEF26 1.4139 | ARHGEF10L 1.4113 | FGD1 1.4085 | ARHGEF40 1.3953 | VAV1 1.3902 | BCR 1.3878 | DENND1A 1.3576 | ALS2 1.3539 | TBC1D10A 1.3510 | RAPGEFL1 1.3456 | RANBP10 1.3283 | RASGRP3 1.3202 | CYTH2 1.3153 | RCBTB2 1.3141 | NGEF 1.3111 | HERC1 1.3063 | GAPVD1 1.2903 | ARHGEF15 1.2884 | ARHGEF12 1.2882 | EIF2B5 1.2665 | PSD4 1.1995 | PSD2 1.1949 | C9orf100 1.1946 | DNMBP 1.1537 | DENND1B 1.1516 | SOS1 1.1496 | RALGDS 1.1461 | ARHGEF25 1.1372 | CYTH4 1.1353 | ARHGEF7 1.1278 | SH2D3A 1.1155 | RASGRP2 1.1008 | ARHGEF33 1.0894 | ARHGEF2 1.0873 | P2RY12 1.0857 | RGL3 1.0733 | PLEKHG4B 1.0721 | FNIP1 0.9968 | EIF2B1 0.9926 | RASGEF1A 0.9575 | RAB3IP 0.9465 | ARHGEF19 0.9428 | EIF2B3 0.9340 | ARHGEF17 0.9078 | ARHGEF1 0.8908 | PLEKHG3 0.8754 | TAGAP 0.8665 | PTGIR 0.8371 | RABIF 0.7955 | RANGRF 0.7954 | RIC8A 0.6441 | ARHGEF6 0.6228 | ECT2 0.5904 | GCGR 0.5351 | PLEKHG4 0.4639 | EIF2B2 0.2862 | RCC1 0.1854 | ARFGEF3 | C15orf58 | DKFZp781P1719 | DOCK10.2 | FLJ00017 | RP11-114F7.3 | ||||||||||||||||||||||||||||||||||||||||
synapse organization (boxplot) | 78 | 83 | 3.517642367610031 | 2.1769936211879504E-4 | 0.011819342135887999 | 0.0 | GPHN 5.9364 | CDH2 3.9744 | PTPRD 3.6941 | NRXN1 3.6097 | DNM3 3.4277 | ERBB4 3.2809 | ERBB2 3.2295 | TNR 3.0413 | NFASC 2.9513 | NLGN1 2.7866 | CHAT 2.7603 | MUSK 2.5943 | GLRA2 2.5894 | COL4A1 2.5872 | GPM6A 2.3326 | NLGN4X 2.3043 | MAP1B 2.2447 | PCDHB5 2.2391 | PCDHB6 | CADM1 2.2215 | CACNB2 2.2123 | ANK3 2.1828 | NRG1 2.1819 | DNER 2.1720 | LRP4 2.1606 | APP 2.1303 | SEMA3E 2.0638 | WNT7A 2.0616 | PDZRN3 2.0541 | SHANK3 2.0446 | IL1RAPL1 2.0206 | CACNA1A 1.9305 | TNC 1.9083 | AFG3L2 1.8657 | WNT7B 1.8583 | TG 1.8438 | DLG4 1.7370 | PALM 1.7163 | NLGN3 1.5936 | PCDHB4 1.5866 | DRD2 1.5853 | LRRK2 1.5730 | CDK5 1.5715 | MYO5A 1.5529 | NRCAM 1.5362 | AGRN 1.5051 | LAMB2 1.4979 | DRD1 1.4777 | F2R 1.4291 | DNAJA3 1.4206 | CACNA1S 1.3954 | PTEN 1.3846 | CACNG2 1.3692 | ALS2 1.3539 | SNAPIN 1.3340 | TSC1 1.3322 | CHRNA1 1.3109 | COL4A5 1.3070 | PCDHB14 1.2770 | DVL1 1.2676 | CDH1 1.2150 | DOK7 1.2147 | GNPAT 1.2058 | PCDHB11 1.1775 | PCDHB13 | PCDHB10 1.1729 | PCDHB16 | PCDHB9 | SPOCK2 1.1539 | POU4F1 1.0505 | NRD1 1.0284 | PCDHB2 1.0236 | PCDHB3 0.9967 | NRXN2 0.9962 | GJA10 0.9943 | PLXND1 0.9796 | ACHE 0.9394 | PAK3 0.8800 | NLGN2 0.6604 | SNTA1 0.5644 | RAB39B 0.5586 | CTNNB1 0.5466 | NLGN4Y | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ion channel complex (boxplot) | 193 | 196 | 3.5093935511606986 | 2.2456490017797037E-4 | 0.011926348937712643 | 0.0 | SCN3B 4.2468 | GABRG3 3.6968 | SCN2A 3.6519 | CLCN2 3.5399 | KCND3 3.5097 | KCNA5 3.3453 | KCNMA1 3.3055 | KCNA7 3.2839 | KCNJ4 3.2311 | RYR2 3.1737 | CNTNAP2 3.1556 | CACNB4 3.1376 | KCNJ5 3.0325 | CACNA1G 3.0242 | GABRB3 2.9924 | KCNQ5 2.9323 | CACNA1C 2.8754 | KCNQ4 2.8155 | AKAP6 2.7555 | CACNG3 2.6709 | KCNMB2 2.6357 | ANO9 2.6333 | SCN11A 2.6313 | GABRR3 2.6005 | ANO4 2.5994 | PEX5L 2.5959 | GLRA2 2.5894 | KCNQ1 2.5850 | CLIC1 2.5788 | KCNH1 2.5742 | CNGB1 2.5546 | SCN9A 2.5308 | CACNA1H 2.4410 | GABRA3 2.4286 | KCNMB3 2.4149 | SESTD1 2.4004 | KCNC4 2.3714 | ANO10 2.3283 | CHRNB1 2.2963 | CNTN2 2.2820 | CATSPERD 2.2698 | SCN5A 2.2668 | KCNE2 2.2438 | CACNB2 2.2123 | GABRG1 2.2106 | KCNQ3 2.2037 | SCN8A 2.1612 | BEST3 2.1324 | CACNA1D 2.1182 | CACNA1E 2.0970 | HCN2 2.0858 | GABRA5 2.0812 | ANO1 2.0628 | CATSPERB 2.0624 | KCNJ6 2.0282 | GABRQ 1.9995 | CACNA2D1 1.9982 | CACNG7 1.9540 | KCNMB4 1.9400 | CACNA1A 1.9305 | KCNB2 1.9269 | KCNT2 1.9253 | KCNT1 1.9150 | KCNA2 1.8775 | KCNC1 1.8772 | CLIC6 1.8748 | SCN1A 1.8708 | CATSPER1 1.8550 | CHRNA2 1.8484 | CACNA1B 1.8481 | KCNN1 1.8466 | CATSPERG 1.8461 | KCNE1 1.8416 | CACNG1 1.8336 | KCNK1 1.8306 | KCNIP2 1.8243 | KCNH2 1.8168 | CNGA2 1.8158 | KCNC2 1.8152 | GABRG2 1.8133 | TTYH1 1.7790 | CLIC4 1.7778 | CATSPER4 1.7557 | CHRND 1.7516 | KCNA1 1.7305 | GABRR1 1.7119 | GABRB2 1.7081 | ABCC9 1.7062 | ANO8 1.6992 | CACNG6 1.6930 | ANO2 1.6772 | CHRNA7 1.6719 | GABRB1 1.6717 | GLRA3 1.6714 | TTYH2 1.6608 | CLIC5 1.6546 | TTYH3 1.6392 | KCNJ3 1.6361 | TRPC4 1.6274 | KCNB1 1.6104 | CACNA1I 1.6100 | TRPC5 1.6072 | BEST2 1.6024 | SCN10A 1.5853 | SCN7A 1.5790 | GABRA1 1.5731 | ANO7 1.5286 | CHRNA9 1.5108 | KCNN4 1.5095 | ANO6 1.4896 | CLCN1 1.4840 | CHRNG 1.4825 | CHRNE 1.4611 | SNAP25 1.4539 | CLCNKA 1.4493 | CLCNKB | GLRA1 1.4443 | KCNA6 1.4115 | ANO3 1.4085 | CACNA1S 1.3954 | KCNJ16 1.3936 | SCN3A 1.3785 | CFTR 1.3770 | KCNJ14 1.3766 | CACNG2 1.3692 | ATP2A1 1.3612 | FXYD1 1.3508 | FXYD3 | KCNA10 1.3288 | SCN1B 1.3219 | CHRNA1 1.3109 | FKBP1B 1.3101 | PPM1A 1.3037 | KCNG3 1.2978 | KCNJ1 1.2945 | KCND2 1.2892 | KCNE1L 1.2837 | ANO5 1.2831 | GABRD 1.2730 | KCNG2 1.2727 | CACNG8 1.2699 | KCNG4 1.2667 | CNTNAP1 1.2662 | LRRC26 1.2637 | GABRP 1.2409 | KCNQ2 1.2247 | SCN4B 1.2124 | GABRA2 1.2072 | GLRA4 1.2033 | CHRNA4 1.2001 | KCNK2 1.1962 | CHRNA3 1.1921 | CHRNB4 | GLRB 1.1896 | KCNK6 1.1799 | GABRE 1.1782 | CACNB1 1.1775 | KCNV1 1.1761 | KCNS1 1.1656 | KCNJ11 1.1557 | CHRNA5 1.1534 | STXBP5 1.1492 | KCNS2 1.1460 | KCNJ8 1.1442 | BEST4 1.1387 | KCNF1 1.1068 | KCNH4 1.0789 | KCNU1 1.0750 | KCNMB1 1.0743 | KCNV2 1.0713 | BEST1 1.0633 | CATSPER3 1.0602 | SCN2B 1.0517 | KCNS3 1.0343 | CLCA3P 1.0301 | CLIC3 1.0168 | KCNG1 0.9673 | CACNA1F 0.9583 | CHRNB2 0.9425 | HSPA2 0.9003 | GABRR2 0.8946 | CNGA4 0.8741 | GABRA6 0.8703 | SCN4A 0.8170 | KCNC3 0.8056 | GABRA4 0.7578 | CACNB3 0.7536 | KCNA3 0.7220 | CATSPER2 0.6702 | KCNA4 0.6180 | PPP2R4 0.6040 | KCND1 0.5914 | CLIC2 0.5586 | KCNJ13 0.4431 | CHRNA6 0.3958 | CHRNB3 0.3372 | |||||||||||
startle response (boxplot) | 19 | 19 | 3.509294976253025 | 2.2464815324019227E-4 | 0.011926348937712643 | 0.0 | NRXN1 3.6097 | PCDH15 3.5572 | PARK2 3.3357 | GRIN3A 3.1467 | FABP7 3.0449 | GRID2 3.0003 | CTNNA2 2.3669 | GRIN2B 2.2951 | GRIN2A 2.0931 | DRD3 1.9435 | DRD2 1.5853 | DRD1 1.4777 | GLRA1 1.4443 | PTEN 1.3846 | GRIN2D 1.3766 | ADORA2A 1.3027 | DVL1 1.2676 | SLC6A3 1.1970 | GLRB 1.1896 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ventricular septum development (boxplot) | 32 | 32 | 3.4905278898395418 | 2.4103364700445162E-4 | 0.012528621268763305 | 0.0 | HEG1 4.0972 | SALL4 3.8389 | HES1 3.7965 | HOXA13 2.9921 | PROX1 2.8868 | FGFR2 2.7650 | TBX3 2.6289 | FRS2 2.5419 | FZD1 2.4363 | ZFPM2 2.2503 | NKX2-5 2.2385 | WNT11 2.1927 | SAV1 2.0321 | TBX5 1.9756 | GATA4 1.9478 | LMO4 1.8840 | FZD2 1.8049 | DAND5 1.7318 | RBM15 1.6666 | CYR61 1.6494 | FGFRL1 1.6492 | SOX11 1.6081 | GATA3 1.5648 | STRA6 1.5142 | ZFPM1 1.4872 | SMAD7 1.4674 | WNT5A 1.3655 | SALL1 1.1703 | EGLN1 0.9579 | SOX4 0.8314 | WHSC1 0.6859 | CITED2 0.4310 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
outer membrane-bounded periplasmic space (boxplot) | 13 | 13 | 3.484153943836687 | 2.468477182102635E-4 | 0.012695767907108923 | 0.0 | GRID1 5.7829 | GRIA4 3.3765 | GRIN3A 3.1467 | GRID2 3.0003 | GRIN2B 2.2951 | GRIN2A 2.0931 | GRIN2C 1.9757 | GRIK1 1.8243 | GRIN2D 1.3766 | GRIN1 1.2637 | GRIA1 1.1475 | GRIN3B 1.0627 | GRIA2 0.9514 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
periplasmic space (boxplot) | 13 | 13 | 3.484153943836687 | 2.468477182102635E-4 | 0.012695767907108923 | 0.0 | GRID1 5.7829 | GRIA4 3.3765 | GRIN3A 3.1467 | GRID2 3.0003 | GRIN2B 2.2951 | GRIN2A 2.0931 | GRIN2C 1.9757 | GRIK1 1.8243 | GRIN2D 1.3766 | GRIN1 1.2637 | GRIA1 1.1475 | GRIN3B 1.0627 | GRIA2 0.9514 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Rho guanyl-nucleotide exchange factor activity (boxplot) | 74 | 75 | 3.4738364945867133 | 2.565367905672522E-4 | 0.012922049058882414 | 0.0 | ARHGEF10 3.8915 | SPATA13 3.6908 | KALRN 3.6105 | PLEKHG2 3.4715 | PLEKHG1 3.2405 | PREX1 2.9502 | RASGRF1 2.9288 | ARHGEF3 2.8881 | AKAP13 2.8539 | TIAM1 2.8400 | RGNEF 2.6947 | MCF2 2.4868 | RASGRF2 2.4633 | TIAM2 2.4489 | FGD2 2.4194 | FARP1 2.2734 | FARP2 2.2728 | DOCK2 2.2237 | MCF2L2 2.2166 | ARHGEF18 2.2107 | ARHGEF38 2.2024 | PREX2 2.2018 | ITSN2 2.1500 | TRIO 2.1284 | ARHGEF9 2.0887 | FGD4 2.0673 | ARHGEF5 2.0614 | ARHGEF11 2.0462 | ITSN1 2.0433 | DOCK11 2.0111 | FGD5 1.9928 | VAV2 1.9727 | PLEKHG7 1.9482 | OBSCN 1.9276 | VAV3 1.8406 | ABR 1.7595 | DOCK10 1.7553 | ALS2CL 1.6454 | ARHGEF4 1.6452 | ARHGEF37 1.6201 | PLEKHG5 1.5723 | ARHGEF16 1.5691 | PLEKHG6 1.5603 | MCF2L 1.5518 | FGD6 1.5470 | ECT2L 1.5269 | SOS2 1.5227 | FGD3 1.4630 | NET1 1.4291 | ARHGEF26 1.4139 | ARHGEF10L 1.4113 | FGD1 1.4085 | ARHGEF40 1.3953 | VAV1 1.3902 | BCR 1.3878 | ALS2 1.3539 | NGEF 1.3111 | ARHGEF15 1.2884 | ARHGEF12 1.2882 | C9orf100 1.1946 | DNMBP 1.1537 | SOS1 1.1496 | ARHGEF25 1.1372 | ARHGEF7 1.1278 | ARHGEF33 1.0894 | ARHGEF2 1.0873 | PLEKHG4B 1.0721 | ARHGEF19 0.9428 | ARHGEF17 0.9078 | ARHGEF1 0.8908 | PLEKHG3 0.8754 | ARHGEF6 0.6228 | ECT2 0.5904 | PLEKHG4 0.4639 | RP11-114F7.3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
generation of a signal involved in cell-cell signaling (boxplot) | 127 | 129 | 3.469039570600521 | 2.611612579787037E-4 | 0.01302075414779537 | 0.0 | ADORA3 4.1949 | VAMP1 4.1635 | PCLO 4.0360 | GHRH 3.4507 | CPLX2 3.2544 | FAM3B 2.8209 | NLGN1 2.7866 | PPFIA3 2.7612 | CHAT 2.7603 | SLC18A3 | GPR119 2.7157 | STX1A 2.7012 | XBP1 2.6965 | SNPH 2.6851 | SYN2 2.6795 | SYT1 2.6792 | STXBP1 2.6367 | TBX3 2.6289 | SPTBN2 2.5986 | CADPS 2.5522 | HRH3 2.5237 | LRP2 2.5159 | MAFA 2.5049 | VGF 2.3948 | EDN1 2.3459 | SEPT5 2.2712 | O3FAR1 2.2565 | SLC22A2 2.2511 | TRPV1 2.1980 | CAMK2G 2.1818 | GLS 2.1689 | SYK 2.1149 | SLC18A2 2.0880 | CCKAR 2.0865 | SYN3 2.0801 | ACVR2B 2.0747 | WNT7A 2.0616 | APBA1 2.0498 | EXOC3L1 2.0447 | TRPV4 2.0262 | BAIAP3 2.0183 | HTT 2.0106 | HNF1B 1.9806 | P2RX1 1.9501 | RIMS1 1.9395 | AP2B1 1.9360 | CACNA1A 1.9305 | UNC13B 1.8915 | SYT4 1.8726 | P2RX7 1.8574 | SLC5A7 1.8496 | CACNA1B 1.8481 | FFAR1 1.8156 | ANXA1 1.8032 | PPT1 1.7921 | YWHAZ 1.7916 | GRM4 1.7819 | SLC17A7 1.7655 | ADM 1.7485 | SLC6A12 1.7455 | PIP5K1C 1.7353 | SLC30A8 1.7213 | GHSR 1.7166 | IL6 1.7153 | DGAT1 1.7111 | BRSK1 1.7013 | RAPGEF4 1.6971 | CPLX1 1.6807 | UNC13A 1.6800 | DOC2B 1.6682 | GHRHR 1.6541 | OTOF 1.6397 | SLC32A1 1.6305 | TRPC4 1.6274 | INHBA 1.6220 | HNF1A 1.6105 | LYN 1.5986 | SLC38A2 1.5792 | CDK5 1.5715 | MYO5A 1.5529 | SLC6A11 1.5526 | MEG3 1.5421 | GIPC1 1.5412 | DOC2A 1.5395 | CARTPT 1.4844 | SYN1 1.4729 | SLC6A1 1.4647 | SNAP25 1.4539 | RAB3A 1.4334 | LEP 1.4143 | ABAT 1.3792 | SMPD3 1.3729 | SNAPIN 1.3340 | FKBP1B 1.3101 | HSPA8 1.2788 | DNAJC5 1.2774 | DVL1 1.2676 | SYT2 1.2635 | GLS2 1.2509 | ILDR2 1.2325 | BDNF 1.2240 | GAL 1.2052 | CGA 1.1299 | EDN3 1.1118 | CPLX3 1.1056 | PLDN 1.1027 | MC4R 1.1026 | GRM2 1.0960 | GAD1 1.0859 | PDX1 1.0828 | ALDH5A1 1.0747 | VAMP2 1.0699 | FCER1A 1.0656 | CYB5R4 1.0293 | PSEN1 1.0274 | SLC6A13 1.0084 | SMAD2 1.0065 | GHRL 0.9974 | FCER1G 0.8951 | GAD2 0.8924 | RAB14 0.7921 | EIF2AK3 0.7800 | LTBP4 0.7647 | NEUROD1 0.7493 | FZD4 0.7448 | STX4 0.6681 | SYNJ1 0.6101 | MAOA 0.3928 | F5H0A2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
signal release (boxplot) | 127 | 129 | 3.469039570600521 | 2.611612579787037E-4 | 0.01302075414779537 | 0.0 | ADORA3 4.1949 | VAMP1 4.1635 | PCLO 4.0360 | GHRH 3.4507 | CPLX2 3.2544 | FAM3B 2.8209 | NLGN1 2.7866 | PPFIA3 2.7612 | CHAT 2.7603 | SLC18A3 | GPR119 2.7157 | STX1A 2.7012 | XBP1 2.6965 | SNPH 2.6851 | SYN2 2.6795 | SYT1 2.6792 | STXBP1 2.6367 | TBX3 2.6289 | SPTBN2 2.5986 | CADPS 2.5522 | HRH3 2.5237 | LRP2 2.5159 | MAFA 2.5049 | VGF 2.3948 | EDN1 2.3459 | SEPT5 2.2712 | O3FAR1 2.2565 | SLC22A2 2.2511 | TRPV1 2.1980 | CAMK2G 2.1818 | GLS 2.1689 | SYK 2.1149 | SLC18A2 2.0880 | CCKAR 2.0865 | SYN3 2.0801 | ACVR2B 2.0747 | WNT7A 2.0616 | APBA1 2.0498 | EXOC3L1 2.0447 | TRPV4 2.0262 | BAIAP3 2.0183 | HTT 2.0106 | HNF1B 1.9806 | P2RX1 1.9501 | RIMS1 1.9395 | AP2B1 1.9360 | CACNA1A 1.9305 | UNC13B 1.8915 | SYT4 1.8726 | P2RX7 1.8574 | SLC5A7 1.8496 | CACNA1B 1.8481 | FFAR1 1.8156 | ANXA1 1.8032 | PPT1 1.7921 | YWHAZ 1.7916 | GRM4 1.7819 | SLC17A7 1.7655 | ADM 1.7485 | SLC6A12 1.7455 | PIP5K1C 1.7353 | SLC30A8 1.7213 | GHSR 1.7166 | IL6 1.7153 | DGAT1 1.7111 | BRSK1 1.7013 | RAPGEF4 1.6971 | CPLX1 1.6807 | UNC13A 1.6800 | DOC2B 1.6682 | GHRHR 1.6541 | OTOF 1.6397 | SLC32A1 1.6305 | TRPC4 1.6274 | INHBA 1.6220 | HNF1A 1.6105 | LYN 1.5986 | SLC38A2 1.5792 | CDK5 1.5715 | MYO5A 1.5529 | SLC6A11 1.5526 | MEG3 1.5421 | GIPC1 1.5412 | DOC2A 1.5395 | CARTPT 1.4844 | SYN1 1.4729 | SLC6A1 1.4647 | SNAP25 1.4539 | RAB3A 1.4334 | LEP 1.4143 | ABAT 1.3792 | SMPD3 1.3729 | SNAPIN 1.3340 | FKBP1B 1.3101 | HSPA8 1.2788 | DNAJC5 1.2774 | DVL1 1.2676 | SYT2 1.2635 | GLS2 1.2509 | ILDR2 1.2325 | BDNF 1.2240 | GAL 1.2052 | CGA 1.1299 | EDN3 1.1118 | CPLX3 1.1056 | PLDN 1.1027 | MC4R 1.1026 | GRM2 1.0960 | GAD1 1.0859 | PDX1 1.0828 | ALDH5A1 1.0747 | VAMP2 1.0699 | FCER1A 1.0656 | CYB5R4 1.0293 | PSEN1 1.0274 | SLC6A13 1.0084 | SMAD2 1.0065 | GHRL 0.9974 | FCER1G 0.8951 | GAD2 0.8924 | RAB14 0.7921 | EIF2AK3 0.7800 | LTBP4 0.7647 | NEUROD1 0.7493 | FZD4 0.7448 | STX4 0.6681 | SYNJ1 0.6101 | MAOA 0.3928 | F5H0A2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cAMP binding (boxplot) | 20 | 20 | 3.4656222362983917 | 2.6450299626157303E-4 | 0.01302075414779537 | 0.0 | PDE2A 3.7330 | PDE10A 3.5081 | PDE11A 2.9328 | PDE4D 2.8834 | RAPGEF3 2.6418 | CNGB1 2.5546 | PDE3A 2.3821 | HCN1 2.2865 | PDE1C 2.1963 | PRKAR1B 2.1387 | HCN2 2.0858 | CNGA2 1.8158 | PRKAR2B 1.7791 | PDE3B 1.7081 | RAPGEF4 1.6971 | HCN4 1.5579 | PRKAR1A 1.3889 | PRKAR2A 1.3064 | CNGA4 0.8741 | HCN3 0.8529 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cell projection membrane (boxplot) | 176 | 178 | 3.4590579325162802 | 2.710341492491164E-4 | 0.013111612408229532 | 0.0 | MYO1C 4.9972 | PLEK2 4.4907 | BBS5 3.9745 | SPATA13 3.6908 | SNTG1 3.5587 | INPP5K 3.5378 | LCP1 3.4460 | MACF1 3.3194 | MYO1D 3.2744 | NF2 3.2554 | CNTNAP2 3.1556 | BBS1 3.1352 | ROBO2 3.0085 | CUBN 2.9709 | PODXL 2.9223 | KIRREL 2.8815 | CYBRD1 2.8699 | SYNJ2 2.7782 | SCARB1 2.6205 | BBS9 2.5601 | LRP2 2.5159 | SLC12A5 2.5026 | SLC5A1 2.4893 | SLC6A14 2.4496 | FZD1 2.4363 | PROM2 2.4352 | CSPG4 2.4209 | SLC34A1 2.4197 | FGD2 2.4194 | SHANK2 2.3841 | APC2 2.3743 | GNA12 2.3370 | DPP4 2.3359 | EVC 2.3039 | PLD2 2.2800 | SEPT2 2.2728 | CATSPERD 2.2698 | TRPV1 2.1980 | ROBO1 2.1673 | FERMT1 2.1644 | AQP7 2.1271 | FZD7 2.1227 | BBS2 2.0939 | PIP5K1A 2.0835 | USH2A 2.0822 | AIF1 2.0797 | SHANK3 2.0446 | PLA2G4F 2.0368 | TRPV4 2.0262 | DDN 2.0180 | RAB35 1.9916 | PDPN 1.9883 | SLC22A5 1.9715 | GABBR1 1.9622 | DDX58 1.9596 | TWF1 1.9582 | SLC27A4 1.9556 | PROM1 1.9541 | OPRD1 1.9420 | MYO6 1.9297 | ANTXR1 1.9030 | RHOA 1.8947 | PTH1R 1.8709 | DLG1 1.8617 | CATSPER1 1.8550 | EVC2 1.8546 | SYNE2 1.8459 | KCNK1 1.8306 | GABRG2 1.8133 | FZD2 1.8049 | PPP1R9B 1.8018 | MYO10 1.7867 | SLC1A2 1.7777 | PDE9A 1.7763 | CLASP2 1.7640 | MAPK8IP3 1.7605 | EMR2 1.7564 | CATSPER4 1.7557 | PIP5K1C 1.7353 | FZD6 1.7328 | SLC9A3 1.7279 | PALM 1.7163 | SHISA9 1.7162 | AQP1 1.7153 | TMEM17 1.7112 | ADORA1 1.7070 | SLC22A12 1.7065 | PEMT 1.6828 | ATP6V0A4 1.6520 | FZD3 1.6473 | ARHGEF4 1.6452 | TIRAP 1.6414 | LAMP5 1.6266 | SLC9C1 1.6247 | GAP43 1.6161 | GNA13 1.6039 | TPM1 1.5971 | ATP7A 1.5814 | PTPRJ 1.5709 | WWC1 1.5654 | BBS4 1.5605 | TAS2R4 1.5526 | TMEM67 1.5422 | SCIMP 1.5326 | TAS2R43 1.5294 | TAS2R46 1.5294 | NOX1 1.5261 | APC 1.5096 | ADAM17 1.5056 | MUC20 1.4838 | SFRP4 1.4173 | CASK 1.4083 | THEM4 1.3903 | ATP8B1 1.3825 | SLC17A3 1.3665 | DIAPH1 1.3602 | VASP 1.3560 | DPEP1 1.3546 | FAP 1.3432 | ADORA2A 1.3027 | DRD5 1.2989 | PLEK 1.2748 | BMX 1.2654 | CFL1 1.2636 | TMEM231 1.2537 | MTTP 1.2284 | ARL6 1.2139 | PLEKHA1 1.2069 | CA9 1.1946 | UMOD 1.1937 | RPS3 1.1846 | FGR 1.1781 | EPHA2 1.1715 | PDZK1 1.1602 | ARF6 1.1563 | SLC39A6 1.1470 | SPRY4 1.1386 | EZR 1.1330 | ITGB1 1.1192 | RASGRP2 1.1008 | SLC2A2 1.0978 | ARHGEF2 1.0873 | TRPM6 1.0811 | MAPRE1 1.0809 | FZD9 1.0715 | CATSPER3 1.0602 | TTC8 1.0556 | AIF1L 1.0549 | CDKL5 1.0190 | PEX19 1.0031 | CYS1 0.9956 | SLC34A3 0.9856 | SLC34A2 0.9793 | TLN1 0.9695 | SPRY2 0.9548 | BBS7 0.9228 | CA4 0.8965 | RAB25 0.8797 | EPB41L5 0.8760 | SLC5A6 0.8757 | GABARAPL3 0.8713 | ITGA5 0.8380 | NCKAP1 0.8251 | FRZB 0.8133 | B4GALT1 0.8108 | ITLN1 0.8094 | KCNC3 0.8056 | ADCY6 0.7536 | PDE4A 0.7502 | MSN 0.7412 | SLC9A3R1 0.7026 | CATSPER2 0.6702 | AQP7P3 0.5966 | CTNNB1 0.5466 | PDXP 0.5140 | SLC5A2 0.4536 | PDZK1P1 | SMVT | |||||||||||||||||||||||||||||
negative regulation of DNA damage response, signal transduction by p53 class mediator (boxplot) | 11 | 11 | 3.4563893028567967 | 2.737320090521189E-4 | 0.013112299963026009 | 0.0 | SIRT1 7.4176 | SNAI2 2.6919 | KDM1A 2.5909 | CD44 2.4166 | MIF 2.1324 | TWIST1 2.0979 | DYRK1A 1.6138 | SNAI1 1.3990 | PSMD10 1.2562 | CD74 1.0390 | MDM2 0.7327 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
telencephalon development (boxplot) | 153 | 154 | 3.4538330758801883 | 2.763396745929514E-4 | 0.013112299963026009 | 0.0 | ARX 6.2843 | YWHAE 4.5001 | HES1 3.7965 | ERBB4 3.2809 | SLIT1 3.2641 | FOXP2 3.2196 | CNTNAP2 3.1556 | TNR 3.0413 | PTPRS 3.0117 | ROBO2 3.0085 | DAB1 2.9720 | NR2E1 2.8955 | FEZF1 2.8875 | PROX1 2.8868 | TACC2 2.8635 | SLIT2 2.8500 | EGFR 2.8090 | NTRK2 2.7766 | SLC8A1 2.7718 | EPHB2 2.7088 | PLCB1 2.6151 | CXCL12 2.5696 | SLIT3 2.4489 | OXTR 2.3881 | PCNT 2.3313 | GLI3 2.3270 | DPCD 2.3241 | RTN4 2.3237 | CDON 2.3231 | OGDH 2.3215 | GRIN2B 2.2951 | CNTN2 2.2820 | NCOR2 2.2598 | RELN 2.2249 | EXT1 2.2085 | SRD5A1 2.1992 | SKI 2.1799 | EPHA5 2.1737 | ROBO1 2.1673 | TP73 2.1456 | NUMBL 2.1296 | BBS2 2.0939 | GRIN2A 2.0931 | LRP6 2.0780 | SHANK3 2.0446 | NFIB 2.0371 | CDK6 2.0335 | GNG12 2.0311 | TACC1 2.0258 | HTT 2.0106 | LMX1A 1.9808 | TH 1.9742 | CYP19A1 1.9264 | ATOH1 1.9203 | ANXA3 1.9125 | SLC8A3 1.9072 | BCL11B 1.8758 | CEP120 1.8629 | AHSG 1.8397 | LHX2 1.8152 | FEZF2 1.7876 | SLC1A2 1.7777 | LEF1 1.7470 | HSD17B3 1.7371 | AQP1 1.7153 | RYK 1.6892 | ID2 1.6791 | PAX6 1.6766 | HIF1A 1.6618 | LRP8 1.6538 | DPYSL2 1.6469 | WNT3A 1.6407 | PFDN1 1.6401 | EMX2 1.6232 | VLDLR 1.6091 | TACC3 1.5959 | DRD2 1.5853 | NPY 1.5849 | BMP2 1.5776 | LRRK2 1.5730 | FGFR1 1.5730 | CDK5 1.5715 | NDEL1 1.5703 | BBS4 1.5605 | AGTPBP1 1.5597 | NDE1 1.5543 | CYP11A1 1.5384 | FOXP3 1.5343 | MKKS 1.5151 | FOXB1 1.5142 | MYH10 1.4980 | SLC8A2 1.4933 | HTR5A 1.4880 | DICER1 1.4798 | DRD1 1.4777 | ASCL1 1.4512 | HES5 1.4456 | POU3F2 1.4263 | DLX2 1.4133 | PEX5 1.3972 | PTEN 1.3846 | RPGRIP1L 1.3825 | DLX1 1.3713 | WNT5A 1.3655 | SALL3 1.3649 | TSC1 1.3322 | BTG2 1.3309 | CX3CR1 1.2922 | NF1 1.2913 | MDK 1.2489 | SHH 1.2438 | KDM2B 1.2411 | NEUROD6 1.2275 | LHX5 1.2164 | ZEB2 1.2160 | PLXNA3 1.2147 | LHX1 1.2133 | BCAN 1.2096 | POU3F3 1.1996 | CCDC85C 1.1984 | GSK3B 1.1968 | ALDH1A3 1.1799 | SRF 1.1778 | SALL1 1.1703 | ATG7 1.1390 | CYP17A1 1.1376 | ID4 1.1089 | BMP4 1.1081 | LHX6 1.0642 | NUMB 1.0524 | PSEN1 1.0274 | EOMES 1.0250 | KAT2A 0.9979 | MAS1 0.9940 | EFNA2 0.9726 | WDR62 0.9405 | CDK5R1 0.9094 | HDAC2 0.9044 | NR4A3 0.8978 | EMX1 0.8875 | IFT88 0.8853 | PAFAH1B1 0.8148 | HPRT1 0.8115 | NKX2-1 0.7775 | PEX13 0.7502 | NEUROD1 0.7493 | DIXDC1 0.6947 | AVPR1A 0.6808 | TFAP2C 0.6547 | EPHB3 0.6149 | SOX2 0.5800 | UCHL5 0.4659 | UQCRQ 0.4597 | DKFZp434G0625 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
muscle fiber development (boxplot) | 46 | 47 | 3.4520592565071295 | 2.7816276780257E-4 | 0.013112299963026009 | 0.0 | GPHN 5.9364 | ERBB2 3.2295 | TCAP | VEGFA 3.0488 | CAV2 2.8160 | CHAT 2.7603 | MUSK 2.5943 | COL4A1 2.5872 | TTN 2.4386 | CHRNB1 2.2963 | MYH11 2.2753 | MYO18B 2.2179 | CACNB2 2.2123 | HOMER1 2.1943 | CXADR 2.1888 | SKI 2.1799 | DNER 2.1720 | LRP4 2.1606 | APP 2.1303 | PDZRN3 2.0541 | WNT10B 2.0180 | TNC 1.9083 | GPX1 1.8947 | AFG3L2 1.8657 | RCAN1 1.8416 | MYH6 1.8142 | LEF1 1.7470 | MYOG 1.5902 | LRRK2 1.5730 | RYR1 1.5561 | KIAA1161 1.5218 | LAMB2 1.4979 | F2R 1.4291 | PPP3CA 1.4235 | DNAJA3 1.4206 | CACNA1S 1.3954 | CACNG2 1.3692 | ALS2 1.3539 | CHRNA1 1.3109 | COL4A5 1.3070 | MYOD1 1.2690 | DVL1 1.2676 | DOK7 1.2147 | NRD1 1.0284 | ACTA1 0.9736 | PTCD2 0.9115 | SNTA1 0.5644 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
small GTPase binding (boxplot) | 128 | 129 | 3.442667900521866 | 2.8800309156296056E-4 | 0.013401743860729764 | 0.0 | ABCA1 5.6064 | DIAPH3 5.2069 | BICD1 4.2108 | GGA3 3.6421 | DGKI 3.4965 | RILP 3.3070 | FMNL2 3.1102 | RANBP3 3.0390 | RIN3 2.7637 | PEX5L 2.5959 | DMXL2 2.5794 | ADCYAP1R1 2.5080 | MYRIP 2.4991 | RANBP2 2.4302 | NPC1L1 2.4288 | GGA2 2.4207 | FGD2 2.4194 | DOCK4 2.3990 | RABGAP1L 2.3243 | CCDC64B 2.3109 | IPO7 2.2854 | RAP1A 2.2806 | SLC6A4 2.2725 | PARD6A 2.2550 | SYTL2 2.2517 | RAB11FIP4 2.2498 | RAB11FIP3 2.2486 | SRGAP1 2.2338 | ERC1 2.2200 | PRKCH 2.1900 | DAAM2 2.1286 | NDRG1 2.0974 | NSF 2.0876 | KCTD13 2.0841 | FGD4 2.0673 | DIAPH2 2.0407 | RPH3AL 2.0392 | MYO5B 2.0328 | SGSM3 2.0210 | RAP1GAP 2.0128 | DOCK11 2.0111 | PLCE1 2.0072 | INF2 2.0071 | FGD5 1.9928 | CCDC64 1.9916 | RHOH 1.9833 | EXOC2 1.9693 | WDR44 1.9561 | CYFIP1 1.9503 | SYTL3 1.9442 | RIMS1 1.9395 | GIT1 1.9371 | FER 1.8987 | SPHK2 1.8974 | IPO5 1.8683 | EXPH5 1.8496 | RAPGEF6 1.8198 | RAP1B 1.7908 | DOCK10 1.7553 | MAPKAP1 1.7541 | RAPGEF4 1.6971 | RPH3A 1.6628 | TNFAIP1 1.6556 | ALS2CL 1.6454 | CDC42EP5 1.6302 | CDC42BPB 1.6242 | RIMS2 1.5957 | MLPH 1.5851 | RHOBTB3 1.5845 | MAP3K11 1.5775 | LRRK2 1.5730 | ARHGEF16 1.5691 | NUP153 1.5486 | FGD6 1.5470 | BIRC5 1.5440 | PKN1 1.5412 | MAP2K1 1.5376 | GAS8 1.5288 | NOX1 1.5261 | RALBP1 1.5236 | TRIOBP 1.5023 | SYTL1 1.5004 | DAAM1 1.4884 | SYTL5 1.4883 | FGD3 1.4630 | DENND5A 1.4586 | DOCK7 1.4147 | FGD1 1.4085 | ANXA2 1.4037 | NCF2 1.3613 | DIAPH1 1.3602 | ALS2 1.3539 | CDC42EP2 1.3369 | RANBP10 1.3283 | RASGRP3 1.3202 | RANBP1 1.2934 | IQGAP1 1.2792 | DVL1 1.2676 | CDC42EP4 1.2590 | GOLGA5 1.1812 | ROCK1 1.1687 | RANBP9 1.1506 | KIF3B 1.1204 | ZFYVE20 1.1120 | VPS4A 1.0975 | HACE1 1.0906 | ARHGEF2 1.0873 | RGL3 1.0733 | IPO8 1.0311 | CDKL5 1.0190 | BICD2 0.9980 | PFN1 0.9787 | RAB3GAP1 0.9602 | SYTL4 0.9559 | NXT1 0.9369 | FLNA 0.9266 | RGPD8 0.9022 | IQGAP3 0.8907 | RTKN 0.8478 | GRASP 0.8192 | NOXA1 0.8155 | ARFIP2 0.7918 | CHM 0.7897 | FMNL1 0.7139 | STX4 0.6681 | ANXA2P2 0.6424 | ECT2 0.5904 | FMNL3 0.5546 | PIFO | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ovulation (boxplot) | 19 | 19 | 3.4390966782635117 | 2.91829378816999E-4 | 0.013451682499055255 | 0.0 | SIRT1 7.4176 | ADAMTS1 2.9721 | PLA2G4A 2.3298 | AGT 2.2659 | NRIP1 2.1803 | IL1R1 2.0721 | FOXO3 2.0675 | IMMP2L 1.9821 | PTGS2 1.9806 | IL1B 1.8813 | EDN2 1.8797 | HPGD 1.8326 | AFP 1.7611 | NOS3 1.6288 | MMP19 1.5508 | LEP 1.4143 | PGR 1.2410 | CYP17A1 1.1376 | EREG 0.8038 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of cell projection organization (boxplot) | 126 | 128 | 3.435564102143874 | 2.956607764246222E-4 | 0.01350092106178228 | 0.0 | DCC 5.1066 | NTRK3 4.8124 | ARAP1 3.7330 | PTPRD 3.6941 | SCARF1 3.2573 | FES 3.1088 | CDH4 3.0350 | ROBO2 3.0085 | CAMK1 2.9695 | SLIT2 2.8500 | TIAM1 2.8400 | NLGN1 2.7866 | NTRK2 2.7766 | PLXNB2 2.7490 | EPHA3 2.7107 | CDC42EP1 2.6574 | ATF1 2.6336 | FIG4 2.6156 | DSCAM 2.5746 | CXCL12 2.5696 | PTPRF 2.5339 | FNBP1L 2.5333 | CAMK1D 2.4333 | NPTN 2.3588 | BCL11A 2.3352 | GPM6A 2.3326 | CCR7 2.3166 | TNFRSF12A 2.3109 | NGFR 2.2572 | CAMK2B 2.2519 | MAP1B 2.2447 | RELN 2.2249 | STK25 2.1927 | ROBO1 2.1673 | FXN 2.1599 | NUMBL 2.1296 | WNT3 2.0876 | LTK 2.0786 | TWF2 2.0553 | NTRK1 2.0462 | NGF 2.0438 | ISLR2 2.0308 | IL1RAPL1 2.0206 | WNT1 2.0180 | ACTR3 2.0099 | PRKD1 1.9823 | KATNB1 1.9703 | RET 1.9319 | RAC1 1.9125 | RHOA 1.8947 | PLK5 1.8190 | ANAPC2 1.7859 | ABL2 1.7537 | MTOR 1.7516 | DPYSL3 1.7243 | UBE2V2 1.7203 | PALM 1.7163 | PTK7 1.6724 | LRP8 1.6538 | WNT3A 1.6407 | CDC42EP5 1.6302 | SERPINE2 1.6272 | F2RL1 1.6183 | VLDLR 1.6091 | CNR1 1.6061 | MARK2 1.6028 | LYN 1.5986 | BMP7 1.5842 | FGFR1 1.5730 | NDEL1 1.5703 | BBS4 1.5605 | ADNP 1.5371 | CAPRIN1 1.5227 | PRKCQ 1.5129 | APC 1.5096 | EP300 1.4888 | LIF 1.4805 | AMIGO1 1.4658 | P2RY2 1.4186 | SEMA4D 1.3860 | SMAD1 1.3854 | PPP2R5B 1.3670 | WNT5A 1.3655 | NDNF 1.3563 | CDC42EP2 1.3369 | DVL1 1.2676 | CCL19 1.2605 | CCL21 | CDC42EP4 1.2590 | FEZ1 1.2217 | NTN1 1.2089 | AVIL 1.2074 | MIEN1 1.1999 | LCN2 1.1984 | LIMK1 1.1825 | SRF 1.1778 | STK11 1.1724 | WASL 1.1528 | PTK6 1.1515 | RHOQ 1.1486 | MET 1.1441 | TRPV2 1.1404 | ILK 1.1347 | PTK2B 1.1280 | STMN2 1.1280 | TGFBR1 1.1193 | ITGB1 1.1192 | CDC42 1.0907 | CAPRIN2 1.0754 | NUMB 1.0524 | INPP5E 1.0413 | HAP1 1.0381 | CDKL5 1.0190 | TGFB3 1.0107 | PRKCI 0.9445 | BMP5 0.9345 | RAB8B 0.8841 | CNTF 0.8746 | PAFAH1B1 0.8148 | CBFA2T2 0.7972 | SKIL 0.7578 | RALA 0.7339 | SEMA7A 0.7223 | DIXDC1 0.6947 | PLXNB1 0.6552 | ARHGDIA 0.6161 | MAPT 0.4387 | FRAP1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of purine nucleotide biosynthetic process (boxplot) | 91 | 92 | 3.435419769191677 | 2.958183097669931E-4 | 0.01350092106178228 | 0.0 | ABCA1 5.6064 | ADORA3 4.1949 | PDE2A 3.7330 | GHRH 3.4507 | GRM8 3.2143 | GNAL 3.0690 | PID1 2.9916 | GNG7 2.8840 | GRM7 2.8268 | OPRM1 2.8228 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | GUCY1A3 2.4867 | HTR1B 2.3684 | MC1R 2.3626 | EDN1 2.3459 | ADORA2B 2.3294 | GABBR2 2.2343 | GLP1R 2.2306 | PDZD3 2.1882 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | GABBR1 1.9622 | DRD3 1.9435 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | DRD4 1.8319 | ADCYAP1 1.8068 | CAP1 1.7921 | EDNRB 1.7889 | LHCGR 1.7607 | ADM 1.7485 | MTNR1A 1.7179 | PALM 1.7163 | RAF1 1.7090 | GHRHR 1.6541 | NOS3 1.6288 | ADRB1 1.6047 | DRD2 1.5853 | P2RY11 1.5469 | ADNP 1.5371 | NPPC 1.5320 | INSL3 1.5247 | APLP1 1.4983 | DRD1 1.4777 | RAMP1 1.4694 | GNAI3 1.4435 | NPR3 1.4425 | APOE 1.4398 | OXER1 1.4362 | ADCY7 1.4224 | MRAP 1.4047 | LTB4R2 1.3819 | CRHR1 1.3545 | MC5R 1.3486 | NPR1 1.3340 | GRM3 1.3280 | GALR1 1.3255 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | ADRA2A 1.1742 | CCR2 1.1711 | CALCR 1.1467 | MC4R 1.1026 | GRM2 1.0960 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | GALR3 0.8839 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | GNAI2 0.5640 | HCTR-6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of nucleotide biosynthetic process (boxplot) | 91 | 92 | 3.435419769191677 | 2.958183097669931E-4 | 0.01350092106178228 | 0.0 | ABCA1 5.6064 | ADORA3 4.1949 | PDE2A 3.7330 | GHRH 3.4507 | GRM8 3.2143 | GNAL 3.0690 | PID1 2.9916 | GNG7 2.8840 | GRM7 2.8268 | OPRM1 2.8228 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | GUCY1A3 2.4867 | HTR1B 2.3684 | MC1R 2.3626 | EDN1 2.3459 | ADORA2B 2.3294 | GABBR2 2.2343 | GLP1R 2.2306 | PDZD3 2.1882 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | GABBR1 1.9622 | DRD3 1.9435 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | DRD4 1.8319 | ADCYAP1 1.8068 | CAP1 1.7921 | EDNRB 1.7889 | LHCGR 1.7607 | ADM 1.7485 | MTNR1A 1.7179 | PALM 1.7163 | RAF1 1.7090 | GHRHR 1.6541 | NOS3 1.6288 | ADRB1 1.6047 | DRD2 1.5853 | P2RY11 1.5469 | ADNP 1.5371 | NPPC 1.5320 | INSL3 1.5247 | APLP1 1.4983 | DRD1 1.4777 | RAMP1 1.4694 | GNAI3 1.4435 | NPR3 1.4425 | APOE 1.4398 | OXER1 1.4362 | ADCY7 1.4224 | MRAP 1.4047 | LTB4R2 1.3819 | CRHR1 1.3545 | MC5R 1.3486 | NPR1 1.3340 | GRM3 1.3280 | GALR1 1.3255 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | ADRA2A 1.1742 | CCR2 1.1711 | CALCR 1.1467 | MC4R 1.1026 | GRM2 1.0960 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | GALR3 0.8839 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | GNAI2 0.5640 | HCTR-6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of synapse structure and activity (boxplot) | 48 | 49 | 3.4311433691849573 | 3.0052142608194554E-4 | 0.01350092106178228 | 0.0 | NRXN1 3.6097 | SLIT1 3.2641 | ROBO2 3.0085 | CAMK1 2.9695 | NLGN1 2.7866 | ASIC2 2.7474 | EPHB2 2.7088 | EPHB1 2.6334 | PDLIM5 2.6326 | MUSK 2.5943 | PTPRF 2.5339 | THBS2 2.4552 | OXTR 2.3881 | CTNNA2 2.3669 | CAMK2B 2.2519 | RELN 2.2249 | APP 2.1303 | CDC20 2.0817 | WNT7A 2.0616 | SHANK3 2.0446 | MEF2C 2.0426 | CYP19A1 1.9264 | OXT 1.9195 | SYNDIG1 1.8308 | NEUROD2 1.8013 | PPT1 1.7921 | ANAPC2 1.7859 | UBE2V2 1.7203 | GHSR 1.7166 | NLGN3 1.5936 | FRMPD4 1.5631 | PVRL1 1.5566 | ADNP 1.5371 | AGRN 1.5051 | LRRC4B 1.4908 | SNAP25 1.4539 | KLK8 1.4015 | PTK2 1.3822 | WNT5A 1.3655 | ARHGEF15 1.2884 | NCAN 1.2768 | BDNF 1.2240 | SYNGAP1 1.1743 | GHRL 0.9974 | CHRNB2 0.9425 | DMPK 0.8803 | NLGN2 0.6604 | EPHB3 0.6149 | CSPG3 variant protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
negative regulation of fatty acid metabolic process (boxplot) | 14 | 15 | 3.420011684558215 | 3.130922301167738E-4 | 0.013781699426581593 | 0.0 | SIRT1 7.4176 | APOC3 3.0248 | UGT1A7 2.5865 | UGT1A8 2.5865 | UGT1A9 | TRIB3 2.4349 | AKT1 2.1144 | INS 1.9742 | BRCA1 1.7066 | CNR1 1.6061 | APOC1 1.3441 | ACADVL 1.2681 | ACADL 1.2388 | INSIG2 1.0701 | INSIG1 0.6516 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of plasma lipoprotein particle levels (boxplot) | 36 | 39 | 3.409670906976952 | 3.2520655679924015E-4 | 0.014187136040366852 | 0.0 | ABCA1 5.6064 | SOAT1 3.1809 | APOA1 3.0248 | APOC3 | LMF1 2.8542 | SCARB1 2.6205 | APOA4 2.5911 | APOA5 2.5911 | HMOX1 2.3654 | AGT 2.2659 | PLA2G7 2.1676 | LCAT 2.1598 | APOM 2.1586 | LRP6 2.0780 | ABCG1 2.0741 | EHD1 2.0670 | LPL 1.9485 | AGTR1 1.9300 | LDLR 1.9157 | MPO 1.7849 | PLA2G2A 1.7465 | DGAT1 1.7111 | CETP 1.6214 | VLDLR 1.6091 | LIPC 1.6053 | CD36 1.4667 | APOE 1.4398 | LDLRAP1 1.4279 | DGAT2 1.4198 | APOC1 1.3441 | APOC2 | ADIPOQ 1.3289 | LIPG 1.3223 | MSR1 1.2705 | APOB 1.2451 | ABCA5 1.2038 | APOA2 0.8951 | SOAT2 0.7990 | LA16c-360B4.1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lymphocyte costimulation (boxplot) | 65 | 78 | 3.405851585912479 | 3.2979012379408257E-4 | 0.01425977473325564 | 0.0 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | CAV1 3.7656 | FYN 3.7055 | GRB2 3.5564 | CARD11 3.1018 | HLA-DMB 2.6120 | KLRK1 2.5472 | YES1 2.4165 | HLA-DQA1 2.3613 | DPP4 2.3359 | CCR7 2.3166 | PDCD1LG2 2.1876 | CD28 2.1569 | HLA-DRB1 2.1516 | TNFSF13B 2.1364 | CD3D 2.1205 | CD3E 2.1205 | CD3G | AKT1 2.1144 | PTPN11 2.0897 | TNFSF14 2.0782 | CD4 2.0421 | CD274 2.0243 | PIK3R3 2.0057 | CD80 1.9711 | CD86 1.9313 | RAC1 1.9125 | PIK3R1 1.8351 | HLA-DRB5 1.8305 | MAPKAP1 1.7541 | MTOR 1.7516 | HLA-DQB1 1.7437 | GRAP2 1.7178 | PAK2 1.7086 | LYN 1.5986 | SRC 1.5906 | HLA-DOB 1.5897 | MLST8 1.5439 | PDCD1 1.5356 | HLA-DQA2 1.5353 | HLA-DQB2 | HLA-DPA1 1.4883 | HLA-DPB1 | TNFRSF14 1.4456 | PDPK1 1.4292 | MAP3K8 1.4023 | VAV1 1.3902 | TNFRSF13C 1.3592 | PIK3CA 1.3325 | LCK 1.3129 | HLA-DRA 1.2787 | CD247 1.2624 | RICTOR 1.2609 | CCL19 1.2605 | CCL21 | PIK3R2 1.2583 | HLA-DRB3 1.2503 | SPN 1.2252 | ICOS 1.2215 | ICOSLG 1.2062 | PTPN6 1.1681 | CD5 1.1624 | PAK1 1.1424 | CDC42 1.0907 | CSK 1.0827 | CTLA4 1.0433 | BTLA 0.7850 | MAP3K14 0.6324 | CD24 | HLA-DRB4 | P01737 | P04436 | TCRA | TCRB | TRAC | TRBC1 | TRBV12-3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
T cell costimulation (boxplot) | 65 | 78 | 3.405851585912479 | 3.2979012379408257E-4 | 0.01425977473325564 | 0.0 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | CAV1 3.7656 | FYN 3.7055 | GRB2 3.5564 | CARD11 3.1018 | HLA-DMB 2.6120 | KLRK1 2.5472 | YES1 2.4165 | HLA-DQA1 2.3613 | DPP4 2.3359 | CCR7 2.3166 | PDCD1LG2 2.1876 | CD28 2.1569 | HLA-DRB1 2.1516 | TNFSF13B 2.1364 | CD3D 2.1205 | CD3E 2.1205 | CD3G | AKT1 2.1144 | PTPN11 2.0897 | TNFSF14 2.0782 | CD4 2.0421 | CD274 2.0243 | PIK3R3 2.0057 | CD80 1.9711 | CD86 1.9313 | RAC1 1.9125 | PIK3R1 1.8351 | HLA-DRB5 1.8305 | MAPKAP1 1.7541 | MTOR 1.7516 | HLA-DQB1 1.7437 | GRAP2 1.7178 | PAK2 1.7086 | LYN 1.5986 | SRC 1.5906 | HLA-DOB 1.5897 | MLST8 1.5439 | PDCD1 1.5356 | HLA-DQA2 1.5353 | HLA-DQB2 | HLA-DPA1 1.4883 | HLA-DPB1 | TNFRSF14 1.4456 | PDPK1 1.4292 | MAP3K8 1.4023 | VAV1 1.3902 | TNFRSF13C 1.3592 | PIK3CA 1.3325 | LCK 1.3129 | HLA-DRA 1.2787 | CD247 1.2624 | RICTOR 1.2609 | CCL19 1.2605 | CCL21 | PIK3R2 1.2583 | HLA-DRB3 1.2503 | SPN 1.2252 | ICOS 1.2215 | ICOSLG 1.2062 | PTPN6 1.1681 | CD5 1.1624 | PAK1 1.1424 | CDC42 1.0907 | CSK 1.0827 | CTLA4 1.0433 | BTLA 0.7850 | MAP3K14 0.6324 | CD24 | HLA-DRB4 | P01737 | P04436 | TCRA | TCRB | TRAC | TRBC1 | TRBV12-3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of transporter activity (boxplot) | 110 | 110 | 3.4022307679054253 | 3.341908709355579E-4 | 0.01425977473325564 | 0.0 | NRXN1 3.6097 | INSR 3.1624 | CACNB4 3.1376 | SHANK1 3.1256 | EFCAB4B 2.9151 | CACNA1C 2.8754 | OPRM1 2.8228 | NLGN1 2.7866 | CACNG3 2.6709 | YWHAH 2.6079 | PKD2L1 2.5895 | CXCL12 2.5696 | CAMK2D 2.5615 | NDFIP2 2.5605 | TPCN2 2.5016 | STIM1 2.4544 | PLCG2 2.4205 | SESTD1 2.4004 | VDR 2.3912 | CAV3 2.3881 | AGT 2.2659 | SGK1 2.2618 | CACNG4 2.2546 | NKX2-5 2.2385 | GLP1R 2.2306 | RELN 2.2249 | CACNB2 2.2123 | MLL 2.2035 | HOMER1 2.1943 | JPH3 2.1788 | BCL2 2.1766 | CACNA1D 2.1182 | CNIH2 2.1101 | RHOC 2.1005 | TWIST1 2.0979 | CACNA1E 2.0970 | PARK7 2.0872 | CCKAR 2.0865 | RIPK1 2.0686 | SHANK3 2.0446 | IL1RAPL1 2.0206 | CACNA2D1 1.9982 | PKD2 1.9879 | SNCA 1.9846 | INS 1.9742 | GAS6 1.9676 | CACNG7 1.9540 | DRD3 1.9435 | JPH1 1.9422 | OPRD1 1.9420 | ASPH 1.9379 | CACNA1A 1.9305 | CNIH3 1.8983 | SGK2 1.8901 | MAPK8IP2 1.8627 | NDFIP1 1.8539 | CACNA1B 1.8481 | CACNG1 1.8336 | DRD4 1.8319 | ZP3 1.7758 | ITGAV 1.7509 | DLG4 1.7370 | CACNG6 1.6930 | CACNG5 1.6745 | PPARG 1.6692 | NCS1 1.6216 | CACNA1I 1.6100 | ADRB1 1.6047 | NLGN3 1.5936 | PON1 1.5922 | DRD2 1.5853 | WNK2 1.5580 | RYR1 1.5561 | MYO5A 1.5529 | MINK1 1.4611 | STIM2 1.4476 | ACTN4 1.4437 | TRPC6 1.4311 | WWP2 1.4199 | CACNA1S 1.3954 | FKBP1A 1.3770 | CACNG2 1.3692 | DAPK1 1.3354 | SCN1B 1.3219 | FKBP1B 1.3101 | ADORA2A 1.3027 | CACNG8 1.2699 | CACNB1 1.1775 | PLCG1 1.1759 | ADRA2A 1.1742 | JPH2 1.1317 | CALM2 1.1102 | CRHBP 1.0855 | SCN2B 1.0517 | ADRB2 1.0467 | PRKCD 1.0164 | WNK3 0.9692 | CACNA1F 0.9583 | APOA2 0.8951 | CRH 0.8287 | TMEM66 0.8252 | RANGRF 0.7954 | CACNB3 0.7536 | AHCYL1 0.7381 | SLC9A3R1 0.7026 | SYNGR3 0.6909 | NLGN2 0.6604 | GNAI2 0.5640 | EPO 0.4955 | JPH4 0.4863 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
neural precursor cell proliferation (boxplot) | 47 | 47 | 3.3975503017075055 | 3.3996043358097694E-4 | 0.014319367917902184 | 0.0 | ARX 6.2843 | RACGAP1 4.0312 | FABP7 3.0449 | TACC2 2.8635 | MELK 2.8083 | FGFR2 2.7650 | PLXNB2 2.7490 | EPHB1 2.6334 | HMGA2 2.5708 | FRS2 2.5419 | PCNT 2.3313 | GLI3 2.3270 | NCOR2 2.2598 | PCM1 2.2454 | NUMBL 2.1296 | LRP6 2.0780 | WNT7A 2.0616 | ASPM 2.0599 | HHEX 2.0321 | DCT 2.0319 | TACC1 2.0258 | CEP120 1.8629 | LEF1 1.7470 | FZD6 1.7328 | ACSL6 1.6845 | FZD3 1.6473 | WNT3A 1.6407 | ARTN 1.6333 | EMX2 1.6232 | TACC3 1.5959 | FGFR1 1.5730 | ASCL1 1.4512 | POU3F2 1.4263 | SHH 1.2438 | HHIP 1.2311 | LHX5 1.2164 | ZEB2 1.2160 | POU3F3 1.1996 | ID4 1.1089 | NEUROD4 1.0811 | FZD9 1.0715 | NUMB 1.0524 | DBN1 1.0367 | HOOK3 0.9990 | PAFAH1B1 0.8148 | DIXDC1 0.6947 | GBX2 0.5750 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
neutral lipid metabolic process (boxplot) | 92 | 92 | 3.395112168417343 | 3.4300244554752446E-4 | 0.01432401665765132 | 0.0 | SIRT1 7.4176 | LPIN2 5.2136 | CAV1 3.7656 | APOC3 3.0248 | LPCAT1 3.0227 | ELOVL6 2.9754 | PRKACB 2.9293 | GPD1 2.7351 | ACLY 2.7017 | PPP1CB 2.6090 | APOA5 2.5911 | AGPAT4 2.5633 | ABHD5 2.5629 | CDIPT 2.5282 | GPAT2 2.5064 | ELOVL2 2.4805 | MOGAT3 2.4686 | CAV3 2.3881 | PCK1 2.3007 | ACSL1 2.2283 | SLC27A5 2.1872 | LCLAT1 2.1535 | LPIN1 2.1486 | ELOVL1 2.0817 | ACSL5 2.0627 | AGPAT6 2.0214 | AGPAT2 2.0126 | PLCE1 2.0072 | SLC22A4 1.9862 | SNCA 1.9846 | LPL 1.9485 | DGKK 1.9475 | ELOVL7 1.9273 | MOGAT1 1.9020 | GPX1 1.8947 | ALMS1 1.8311 | CPS1 1.8058 | SLC25A1 1.8029 | PNPLA2 1.7743 | PRKACG 1.7616 | AGPAT3 1.7230 | GK 1.7138 | DGAT1 1.7111 | ACSL6 1.6845 | ANG 1.6605 | AGPAT5 1.6333 | LIPF 1.6322 | PNPLA3 1.6241 | CETP 1.6214 | ACSL3 1.6086 | LIPC 1.6053 | CDS2 1.6034 | AGPAT1 1.5913 | DGKD 1.5653 | NKX2-3 1.5542 | HSD17B12 1.5489 | TECR 1.5086 | PNLIPRP2 1.4930 | PCSK9 1.4808 | MGLL 1.4752 | APOE 1.4398 | GPAM 1.4378 | DGAT2 1.4198 | CYP2E1 1.3837 | PLIN1 1.3583 | APOC1 1.3441 | FABP4 1.3200 | PPP1CA 1.3052 | ACSL4 1.2837 | APOB 1.2451 | APOH 1.2376 | MTTP 1.2284 | LIPE 1.1888 | FASN 1.1849 | CPT1A 1.1834 | CEL 1.1461 | ELOVL4 1.1167 | PGS1 1.1094 | INSIG2 1.0701 | GPD1L 1.0398 | PPP1CC 1.0164 | CDS1 1.0042 | MOGAT2 0.9999 | APOA2 0.8951 | ELOVL5 0.8407 | ACACA 0.8142 | PRKACA 0.6979 | CAT 0.6876 | AGPAT9 0.6685 | INSIG1 0.6516 | ELOVL3 0.6419 | G6PC 0.6297 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
leading edge membrane (boxplot) | 89 | 89 | 3.3849585780316427 | 3.559449818681948E-4 | 0.014738535435661015 | 0.0 | PLEK2 4.4907 | SPATA13 3.6908 | SNTG1 3.5587 | INPP5K 3.5378 | LCP1 3.4460 | MACF1 3.3194 | MYO1D 3.2744 | NF2 3.2554 | CNTNAP2 3.1556 | ROBO2 3.0085 | SYNJ2 2.7782 | PTPRK 2.7450 | SLC12A5 2.5026 | FZD1 2.4363 | CSPG4 2.4209 | FGD2 2.4194 | APC2 2.3743 | DPP4 2.3359 | TRPV1 2.1980 | ROBO1 2.1673 | FERMT1 2.1644 | FZD7 2.1227 | PIP5K1A 2.0835 | AIF1 2.0797 | PLA2G4F 2.0368 | TRPV4 2.0262 | DDN 2.0180 | PDPN 1.9883 | GABBR1 1.9622 | DDX58 1.9596 | TWF1 1.9582 | OPRD1 1.9420 | MYO6 1.9297 | ANTXR1 1.9030 | RHOA 1.8947 | SYNE2 1.8459 | GABRG2 1.8133 | FZD2 1.8049 | PPP1R9B 1.8018 | SLC1A2 1.7777 | PDE9A 1.7763 | CLASP2 1.7640 | MAPK8IP3 1.7605 | EMR2 1.7564 | PIP5K1C 1.7353 | FZD6 1.7328 | SHISA9 1.7162 | ADORA1 1.7070 | FZD3 1.6473 | ARHGEF4 1.6452 | TIRAP 1.6414 | LAMP5 1.6266 | TPM1 1.5971 | PTPRJ 1.5709 | WWC1 1.5654 | SCIMP 1.5326 | APC 1.5096 | ADAM17 1.5056 | SFRP4 1.4173 | THEM4 1.3903 | DIAPH1 1.3602 | VASP 1.3560 | FAP 1.3432 | ADORA2A 1.3027 | PLEK 1.2748 | BMX 1.2654 | CFL1 1.2636 | PLEKHA1 1.2069 | RPS3 1.1846 | FGR 1.1781 | EPHA2 1.1715 | SLC39A6 1.1470 | SPRY4 1.1386 | EZR 1.1330 | ITGB1 1.1192 | RASGRP2 1.1008 | ARHGEF2 1.0873 | AIF1L 1.0549 | CDKL5 1.0190 | TLN1 0.9695 | SPRY2 0.9548 | EPB41L5 0.8760 | GABARAPL3 0.8713 | ITGA5 0.8380 | NCKAP1 0.8251 | FRZB 0.8133 | KCNC3 0.8056 | PDE4A 0.7502 | PDXP 0.5140 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
voltage-gated ion channel activity (boxplot) | 175 | 177 | 3.384312329659544 | 3.5678390766236134E-4 | 0.014738535435661015 | 0.0 | KCNJ12 5.2371 | SCN3B 4.2468 | KCNK12 3.7331 | SCN2A 3.6519 | CLCN2 3.5399 | KCND3 3.5097 | KCNA5 3.3453 | KCNMA1 3.3055 | KCNK10 3.2871 | KCNA7 3.2839 | KCNJ4 3.2311 | CACNB4 3.1376 | KCNJ5 3.0325 | CACNA1G 3.0242 | KCNIP4 2.9729 | KCNQ5 2.9323 | CACNA1C 2.8754 | KCNIP1 2.8571 | GRM7 2.8268 | KCNQ4 2.8155 | KCNK9 2.7381 | CACNG3 2.6709 | SCN11A 2.6313 | KCNQ1 2.5850 | CLIC1 2.5788 | KCNH1 2.5742 | SCN9A 2.5308 | TPCN2 2.5016 | CACNA1H 2.4410 | KCNIP3 2.4352 | KCNC4 2.3714 | KCNH5 2.3674 | HCN1 2.2865 | SCN5A 2.2668 | KCNH7 2.2610 | CACNG4 2.2546 | KCNE2 2.2438 | KCNH8 2.2162 | CACNB2 2.2123 | KCNQ3 2.2037 | SCN8A 2.1612 | CACNA1D 2.1182 | CACNA1E 2.0970 | GRIN2A 2.0931 | HCN2 2.0858 | KCNAB1 2.0747 | TRPM5 2.0565 | NALCN 2.0487 | KCNJ6 2.0282 | KCNK18 2.0117 | CACNA2D1 1.9982 | PKD2 1.9879 | GAS6 1.9676 | CACNA2D3 1.9648 | CACNG7 1.9540 | CACNA1A 1.9305 | KCNB2 1.9269 | KCNT2 1.9253 | KCNT1 1.9150 | KCNAB2 1.9081 | KCNA2 1.8775 | KCNC1 1.8772 | CLIC6 1.8748 | SCN1A 1.8708 | CATSPER1 1.8550 | CACNA1B 1.8481 | KCNE1 1.8416 | TMEM37 1.8371 | CACNG1 1.8336 | KCNK13 1.8332 | KCNK1 1.8306 | GRIK1 1.8243 | KCNIP2 1.8243 | KCNH2 1.8168 | KCNC2 1.8152 | VDAC3 1.8137 | CLIC4 1.7778 | TPCN1 1.7668 | CATSPER4 1.7557 | ITGAV 1.7509 | KCNA1 1.7305 | TOMM40 1.7152 | CACNA2D2 1.6959 | CACNG6 1.6930 | CACNG5 1.6745 | KCNK5 1.6574 | CLIC5 1.6546 | KCNJ3 1.6361 | REST 1.6316 | KCNB1 1.6104 | CACNA1I 1.6100 | GPR89B 1.6064 | SCN10A 1.5853 | SCN7A 1.5790 | KCNK7 1.5775 | HCN4 1.5579 | RYR1 1.5561 | NOX1 1.5261 | CYBB 1.5177 | KCNK16 1.5155 | KCNK17 | CLCN1 1.4840 | KCNK4 1.4691 | SNAP25 1.4539 | CLCNKA 1.4493 | CLCNKB | VDAC2 1.4467 | KCNAB3 1.4270 | CACNA2D4 1.4192 | KCNA6 1.4115 | CACNA1S 1.3954 | KCNJ16 1.3936 | SCN3A 1.3785 | GRIN2D 1.3766 | KCNJ14 1.3766 | CACNG2 1.3692 | SLC17A3 1.3665 | VDAC1 1.3400 | KCNA10 1.3288 | SCN1B 1.3219 | KCNG3 1.2978 | KCNJ1 1.2945 | KCND2 1.2892 | KCNG2 1.2727 | CACNG8 1.2699 | KCNG4 1.2667 | HVCN1 1.2377 | KCNQ2 1.2247 | SCN4B 1.2124 | KCNK2 1.1962 | KCNK6 1.1799 | CACNB1 1.1775 | KCNV1 1.1761 | CLCN3 1.1673 | KCNS1 1.1656 | KCNE4 1.1563 | KCNJ11 1.1557 | KCNS2 1.1460 | KCNJ8 1.1442 | CLCN4 1.1291 | FGF2 1.1278 | KCNF1 1.1068 | KCNJ2 1.0875 | KCNH4 1.0789 | KCNU1 1.0750 | KCNV2 1.0713 | CLCN6 1.0642 | CATSPER3 1.0602 | SCN2B 1.0517 | KCNH3 1.0368 | KCNS3 1.0343 | CLCA3P 1.0301 | CLIC3 1.0168 | KCNJ15 1.0099 | KCNG1 0.9673 | CACNA1F 0.9583 | CLCN7 0.9555 | KCNK15 0.9193 | TOMM40L 0.8951 | CLCN5 0.8722 | HCN3 0.8529 | KCNJ10 0.8338 | SCN4A 0.8170 | KCNC3 0.8056 | GPR89A 0.7975 | KCNE3 0.7603 | CACNB3 0.7536 | KCNA3 0.7220 | CATSPER2 0.6702 | KCNA4 0.6180 | KCND1 0.5914 | CLIC2 0.5586 | KCNH6 0.5251 | KCNJ9 0.4817 | KCNJ18 0.4591 | KCNJ13 0.4431 | KCNK3 0.3093 | ||||||||||||||||||||||||||||||
voltage-gated channel activity (boxplot) | 175 | 177 | 3.384312329659544 | 3.5678390766236134E-4 | 0.014738535435661015 | 0.0 | KCNJ12 5.2371 | SCN3B 4.2468 | KCNK12 3.7331 | SCN2A 3.6519 | CLCN2 3.5399 | KCND3 3.5097 | KCNA5 3.3453 | KCNMA1 3.3055 | KCNK10 3.2871 | KCNA7 3.2839 | KCNJ4 3.2311 | CACNB4 3.1376 | KCNJ5 3.0325 | CACNA1G 3.0242 | KCNIP4 2.9729 | KCNQ5 2.9323 | CACNA1C 2.8754 | KCNIP1 2.8571 | GRM7 2.8268 | KCNQ4 2.8155 | KCNK9 2.7381 | CACNG3 2.6709 | SCN11A 2.6313 | KCNQ1 2.5850 | CLIC1 2.5788 | KCNH1 2.5742 | SCN9A 2.5308 | TPCN2 2.5016 | CACNA1H 2.4410 | KCNIP3 2.4352 | KCNC4 2.3714 | KCNH5 2.3674 | HCN1 2.2865 | SCN5A 2.2668 | KCNH7 2.2610 | CACNG4 2.2546 | KCNE2 2.2438 | KCNH8 2.2162 | CACNB2 2.2123 | KCNQ3 2.2037 | SCN8A 2.1612 | CACNA1D 2.1182 | CACNA1E 2.0970 | GRIN2A 2.0931 | HCN2 2.0858 | KCNAB1 2.0747 | TRPM5 2.0565 | NALCN 2.0487 | KCNJ6 2.0282 | KCNK18 2.0117 | CACNA2D1 1.9982 | PKD2 1.9879 | GAS6 1.9676 | CACNA2D3 1.9648 | CACNG7 1.9540 | CACNA1A 1.9305 | KCNB2 1.9269 | KCNT2 1.9253 | KCNT1 1.9150 | KCNAB2 1.9081 | KCNA2 1.8775 | KCNC1 1.8772 | CLIC6 1.8748 | SCN1A 1.8708 | CATSPER1 1.8550 | CACNA1B 1.8481 | KCNE1 1.8416 | TMEM37 1.8371 | CACNG1 1.8336 | KCNK13 1.8332 | KCNK1 1.8306 | GRIK1 1.8243 | KCNIP2 1.8243 | KCNH2 1.8168 | KCNC2 1.8152 | VDAC3 1.8137 | CLIC4 1.7778 | TPCN1 1.7668 | CATSPER4 1.7557 | ITGAV 1.7509 | KCNA1 1.7305 | TOMM40 1.7152 | CACNA2D2 1.6959 | CACNG6 1.6930 | CACNG5 1.6745 | KCNK5 1.6574 | CLIC5 1.6546 | KCNJ3 1.6361 | REST 1.6316 | KCNB1 1.6104 | CACNA1I 1.6100 | GPR89B 1.6064 | SCN10A 1.5853 | SCN7A 1.5790 | KCNK7 1.5775 | HCN4 1.5579 | RYR1 1.5561 | NOX1 1.5261 | CYBB 1.5177 | KCNK16 1.5155 | KCNK17 | CLCN1 1.4840 | KCNK4 1.4691 | SNAP25 1.4539 | CLCNKA 1.4493 | CLCNKB | VDAC2 1.4467 | KCNAB3 1.4270 | CACNA2D4 1.4192 | KCNA6 1.4115 | CACNA1S 1.3954 | KCNJ16 1.3936 | SCN3A 1.3785 | GRIN2D 1.3766 | KCNJ14 1.3766 | CACNG2 1.3692 | SLC17A3 1.3665 | VDAC1 1.3400 | KCNA10 1.3288 | SCN1B 1.3219 | KCNG3 1.2978 | KCNJ1 1.2945 | KCND2 1.2892 | KCNG2 1.2727 | CACNG8 1.2699 | KCNG4 1.2667 | HVCN1 1.2377 | KCNQ2 1.2247 | SCN4B 1.2124 | KCNK2 1.1962 | KCNK6 1.1799 | CACNB1 1.1775 | KCNV1 1.1761 | CLCN3 1.1673 | KCNS1 1.1656 | KCNE4 1.1563 | KCNJ11 1.1557 | KCNS2 1.1460 | KCNJ8 1.1442 | CLCN4 1.1291 | FGF2 1.1278 | KCNF1 1.1068 | KCNJ2 1.0875 | KCNH4 1.0789 | KCNU1 1.0750 | KCNV2 1.0713 | CLCN6 1.0642 | CATSPER3 1.0602 | SCN2B 1.0517 | KCNH3 1.0368 | KCNS3 1.0343 | CLCA3P 1.0301 | CLIC3 1.0168 | KCNJ15 1.0099 | KCNG1 0.9673 | CACNA1F 0.9583 | CLCN7 0.9555 | KCNK15 0.9193 | TOMM40L 0.8951 | CLCN5 0.8722 | HCN3 0.8529 | KCNJ10 0.8338 | SCN4A 0.8170 | KCNC3 0.8056 | GPR89A 0.7975 | KCNE3 0.7603 | CACNB3 0.7536 | KCNA3 0.7220 | CATSPER2 0.6702 | KCNA4 0.6180 | KCND1 0.5914 | CLIC2 0.5586 | KCNH6 0.5251 | KCNJ9 0.4817 | KCNJ18 0.4591 | KCNJ13 0.4431 | KCNK3 0.3093 | ||||||||||||||||||||||||||||||
protein phosphorylated amino acid binding (boxplot) | 19 | 19 | 3.362717621379674 | 3.858963334308907E-4 | 0.015582557728457288 | 0.0 | CRK 4.9972 | YWHAE 4.5001 | GRB2 3.5564 | SAMSN1 3.0213 | PTPN3 2.4191 | PTPN5 1.9934 | NEDD4 1.9836 | CBL 1.9784 | MAPK1 1.9571 | MAPK3 1.8628 | CBLB 1.7575 | BTRC 1.6292 | CBLC 1.5609 | LDLRAP1 1.4279 | ACP2 1.3265 | SHC1 1.2933 | FGR 1.1781 | YWHAB 1.0405 | PIN1 0.6765 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of actin cytoskeleton organization (boxplot) | 156 | 163 | 3.3615418617893984 | 3.875430338471375E-4 | 0.015582557728457288 | 0.0 | CRK 4.9972 | ARHGEF10 3.8915 | ARAP1 3.7330 | CCL24 3.7243 | ACTR3B 3.7214 | INPP5K 3.5378 | PARK2 3.3357 | NF2 3.2554 | FES 3.1088 | ARPC4 2.9695 | SYNPO 2.9309 | PROX1 2.8868 | SLIT2 2.8500 | BAIAP2 2.7979 | SPTBN1 2.7693 | SPTAN1 2.7684 | PRKCE 2.7354 | EPHA3 2.7107 | CCDC88A 2.7048 | EPB49 2.6804 | FZD10 2.6723 | JAM3 2.6353 | SPTBN2 2.5986 | CXCL12 2.5696 | EPHA1 2.5465 | ADD1 2.5292 | SPTBN5 2.4987 | TACSTD2 2.4154 | SERPINF2 2.4022 | CAV3 2.3881 | SORBS3 2.3613 | EDN1 2.3459 | CCR7 2.3166 | FHOD1 2.2999 | DLC1 2.2963 | AMOT 2.2199 | WNT11 2.1927 | ARHGAP6 2.1854 | EPHA5 2.1737 | SHROOM2 2.1572 | ACTR3C 2.1470 | SMAD3 2.1433 | CCL26 2.1094 | RHOC 2.1005 | NEB 2.0865 | LIMA1 2.0815 | ROCK2 2.0790 | SEMA3E 2.0638 | TWF2 2.0553 | EFNA5 2.0515 | MEF2C 2.0426 | VANGL2 2.0307 | ACTR3 2.0099 | MAP3K1 1.9924 | TWF1 1.9582 | FER 1.8987 | RHOA 1.8947 | CAPZA2 1.8696 | LRP1 1.8683 | SPTBN4 1.8647 | TEK 1.8630 | DLG1 1.8617 | CAPZA1 1.8250 | ADD2 1.7611 | ABL2 1.7537 | MTOR 1.7516 | VIL1 1.7405 | CELSR1 1.7341 | MYLK3 1.7219 | DAPK3 1.7213 | KISS1R 1.7173 | ARPC1A 1.7079 | ARPC1B | PFN2 1.7072 | BAIAP2L1 1.6951 | SCIN 1.6737 | PDGFRA 1.6489 | CDC42EP5 1.6302 | F2RL1 1.6183 | TAC1 1.6069 | TPM1 1.5971 | RASA1 1.5836 | KANK1 1.5829 | CDK5 1.5715 | PTGER4 1.5596 | MLST8 1.5439 | PDGFA 1.5347 | PRKCQ 1.5129 | TRIOBP 1.5023 | EP300 1.4888 | HCK 1.4790 | NCK2 1.4470 | MYO1F 1.4447 | ABL1 1.4403 | ARHGEF10L 1.4113 | VILL 1.3837 | BAG4 1.3675 | GPM6B 1.3610 | TACR1 1.3533 | CDC42EP2 1.3369 | TSC1 1.3322 | CAPZB 1.3059 | CCL11 1.3027 | JMY 1.2927 | TMSB10 1.2904 | SDC4 1.2900 | ARHGEF15 1.2884 | SFRP1 1.2842 | PLEK 1.2748 | SPTA1 1.2678 | RICTOR 1.2609 | CCL21 1.2605 | NCKAP1L 1.2593 | DSTN 1.2412 | CSF1R 1.2307 | PDGFRB 1.2307 | ARPC5L 1.2241 | SSH1 1.2178 | AVIL 1.2074 | PPM1F 1.1863 | LIMK1 1.1825 | ROCK1 1.1687 | ARF6 1.1563 | RHOQ 1.1486 | PAK1 1.1424 | ILK 1.1347 | RDX 1.1316 | PTK2B 1.1280 | TMSB15B 1.1148 | SSH3 1.1031 | SPTB 1.0618 | ARPC3 1.0531 | GSN 1.0374 | TMSB15A 1.0351 | S1PR1 1.0347 | PRKCD 1.0164 | CAPG 0.9758 | CORO1A 0.9727 | CTGF 0.9616 | ARHGEF19 0.9428 | WASH2P 0.9218 | CDK5R1 0.9094 | LATS1 0.8990 | GPR65 0.8893 | PAK3 0.8800 | TMSB4X 0.8266 | GRHL3 0.8241 | PHPT1 0.8227 | SSH2 0.7923 | PPM1E 0.7885 | ARPC5 0.7879 | NCK1 0.7460 | DIXDC1 0.6947 | PDXP 0.5140 | ARPC2 0.4034 | WASH1 0.2959 | CAPZA3 0.2266 | FRAP1 | TMSB4Y | TMSL4 | WASH3P | WASH4P | WASH6P | ||||||||||||||||||||||||||||||||||||||||||||
nucleoside monophosphate catabolic process (boxplot) | 23 | 24 | 3.358048450425441 | 3.924742663568015E-4 | 0.015590481832677498 | 0.0 | PDE2A 3.7330 | PDE10A 3.5081 | PDE4B 3.1574 | PRTFDC1 3.1034 | PDE8A 3.0407 | CNP 2.9419 | PDE11A 2.9328 | PDE4D 2.8834 | PDE7B 2.6103 | PDE3A 2.3821 | PDE1C 2.1963 | PDE3B 1.7081 | C6orf108 1.6763 | PDE4C 1.4334 | PDE8B 1.3712 | AMPD3 1.3511 | PDE7A 1.2485 | PDE1B 1.1847 | NT5M 1.1487 | NT5E 1.1463 | PDE5A 1.1185 | HPRT1 0.8115 | PDE4A 0.7502 | RCL | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stereocilium (boxplot) | 20 | 21 | 3.3572051954875404 | 3.936732834832757E-4 | 0.015590481832677498 | 0.0 | MYO1C 4.9972 | PCDH15 3.5572 | MPP1 3.2590 | CDH23 2.9737 | DOCK4 2.3990 | USH2A 2.0822 | TWF2 2.0553 | LOXHD1 2.0404 | PROM1 1.9541 | FSCN2 1.9056 | GRXCR1 1.8854 | TPRN 1.7859 | MYO7A 1.7012 | CLIC5 1.6546 | KPTN 1.4933 | SLC4A7 1.4843 | ESPN 1.4330 | USH1C 1.4192 | RDX 1.1316 | MYO15A 0.7632 | WHRN | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
protein-lipid complex subunit organization (boxplot) | 25 | 27 | 3.354706571619745 | 3.972460477355E-4 | 0.015590481832677498 | 0.0 | ABCA1 5.6064 | SOAT1 3.1809 | APOA1 3.0248 | APOC3 | SCARB1 2.6205 | APOA4 2.5911 | APOA5 2.5911 | AGT 2.2659 | PLA2G7 2.1676 | LCAT 2.1598 | APOM 2.1586 | ABCG1 2.0741 | LPL 1.9485 | AGTR1 1.9300 | MPO 1.7849 | PLA2G2A 1.7465 | DGAT1 1.7111 | CETP 1.6214 | LIPC 1.6053 | APOE 1.4398 | APOC1 1.3441 | APOC2 | LIPG 1.3223 | APOB 1.2451 | ABCA5 1.2038 | APOA2 0.8951 | SOAT2 0.7990 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
plasma lipoprotein particle organization (boxplot) | 25 | 27 | 3.354706571619745 | 3.972460477355E-4 | 0.015590481832677498 | 0.0 | ABCA1 5.6064 | SOAT1 3.1809 | APOA1 3.0248 | APOC3 | SCARB1 2.6205 | APOA4 2.5911 | APOA5 2.5911 | AGT 2.2659 | PLA2G7 2.1676 | LCAT 2.1598 | APOM 2.1586 | ABCG1 2.0741 | LPL 1.9485 | AGTR1 1.9300 | MPO 1.7849 | PLA2G2A 1.7465 | DGAT1 1.7111 | CETP 1.6214 | LIPC 1.6053 | APOE 1.4398 | APOC1 1.3441 | APOC2 | LIPG 1.3223 | APOB 1.2451 | ABCA5 1.2038 | APOA2 0.8951 | SOAT2 0.7990 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
acylglycerol metabolic process (boxplot) | 91 | 91 | 3.3516981796795156 | 4.01587648933166E-4 | 0.015590481832677498 | 0.0 | SIRT1 7.4176 | LPIN2 5.2136 | CAV1 3.7656 | APOC3 3.0248 | LPCAT1 3.0227 | ELOVL6 2.9754 | PRKACB 2.9293 | GPD1 2.7351 | ACLY 2.7017 | PPP1CB 2.6090 | APOA5 2.5911 | AGPAT4 2.5633 | ABHD5 2.5629 | CDIPT 2.5282 | GPAT2 2.5064 | ELOVL2 2.4805 | MOGAT3 2.4686 | CAV3 2.3881 | PCK1 2.3007 | ACSL1 2.2283 | SLC27A5 2.1872 | LCLAT1 2.1535 | LPIN1 2.1486 | ELOVL1 2.0817 | ACSL5 2.0627 | AGPAT6 2.0214 | AGPAT2 2.0126 | PLCE1 2.0072 | SLC22A4 1.9862 | LPL 1.9485 | DGKK 1.9475 | ELOVL7 1.9273 | MOGAT1 1.9020 | GPX1 1.8947 | ALMS1 1.8311 | CPS1 1.8058 | SLC25A1 1.8029 | PNPLA2 1.7743 | PRKACG 1.7616 | AGPAT3 1.7230 | GK 1.7138 | DGAT1 1.7111 | ACSL6 1.6845 | ANG 1.6605 | AGPAT5 1.6333 | LIPF 1.6322 | PNPLA3 1.6241 | CETP 1.6214 | ACSL3 1.6086 | LIPC 1.6053 | CDS2 1.6034 | AGPAT1 1.5913 | DGKD 1.5653 | NKX2-3 1.5542 | HSD17B12 1.5489 | TECR 1.5086 | PNLIPRP2 1.4930 | PCSK9 1.4808 | MGLL 1.4752 | APOE 1.4398 | GPAM 1.4378 | DGAT2 1.4198 | CYP2E1 1.3837 | PLIN1 1.3583 | APOC1 1.3441 | FABP4 1.3200 | PPP1CA 1.3052 | ACSL4 1.2837 | APOB 1.2451 | APOH 1.2376 | MTTP 1.2284 | LIPE 1.1888 | FASN 1.1849 | CPT1A 1.1834 | CEL 1.1461 | ELOVL4 1.1167 | PGS1 1.1094 | INSIG2 1.0701 | GPD1L 1.0398 | PPP1CC 1.0164 | CDS1 1.0042 | MOGAT2 0.9999 | APOA2 0.8951 | ELOVL5 0.8407 | ACACA 0.8142 | PRKACA 0.6979 | CAT 0.6876 | AGPAT9 0.6685 | INSIG1 0.6516 | ELOVL3 0.6419 | G6PC 0.6297 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
neuron projection terminus (boxplot) | 71 | 73 | 3.3503614943719944 | 4.035307980660985E-4 | 0.015590481832677498 | 0.0 | SEPT7 4.3221 | GRIK4 3.9399 | DMD 3.6492 | GHRH 3.4507 | AMPH 3.4482 | GRIA4 3.3765 | CHRM4 3.3170 | GRIK2 3.2889 | PTPRN2 2.8388 | SYNJ2 2.7782 | SLC18A3 2.7603 | SNCG 2.4359 | ATP6V0D1 2.4205 | KCNC4 2.3714 | BIN1 2.3168 | GRIN2B 2.2951 | PRSS12 2.2794 | SEPT5 2.2712 | FSTL3 2.2464 | PCSK1 2.1639 | GRIN2A 2.0931 | SLC18A2 2.0880 | CCKAR 2.0865 | GRIK3 2.0041 | TH 1.9742 | CHRM3 1.9459 | OPRD1 1.9420 | SNCB 1.9380 | CYP19A1 1.9264 | OXT 1.9195 | CHRM2 1.8694 | P2RX7 1.8574 | ESR1 1.8508 | DRD4 1.8319 | GRIK1 1.8243 | DBH 1.8135 | SEPT6 1.7947 | DLG4 1.7370 | TANC1 1.7362 | PFN2 1.7072 | ADORA1 1.7070 | MME 1.6938 | DPYSL2 1.6469 | SLC32A1 1.6305 | DRD2 1.5853 | HCN4 1.5579 | P2RX4 1.5095 | GOT1 1.4481 | P2RX3 1.3783 | GRIN1 1.2637 | TMEM57 1.2211 | ILK 1.1347 | CABP4 1.1126 | MYLK2 1.0997 | CRHBP 1.0855 | CHRM1 1.0409 | HAP1 1.0381 | AAK1 0.9958 | CAD 0.9730 | GRIA2 0.9514 | CCK 0.9390 | PEBP1 0.9211 | NMU 0.8991 | OPHN1 0.8605 | SYP 0.8425 | BSN 0.8423 | UCN 0.8158 | CALCA 0.8098 | KCNC3 0.8056 | DIXDC1 0.6947 | L1CAM 0.6002 | DKFZp586I031 | estrogen receptor | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cerebral cortex development (boxplot) | 65 | 65 | 3.3485367359606624 | 4.0619754959747567E-4 | 0.015590481832677498 | 0.0 | ARX 6.2843 | YWHAE 4.5001 | FOXP2 3.2196 | CNTNAP2 3.1556 | PTPRS 3.0117 | DAB1 2.9720 | NR2E1 2.8955 | TACC2 2.8635 | SLIT2 2.8500 | EGFR 2.8090 | NTRK2 2.7766 | PLCB1 2.6151 | GLI3 2.3270 | RTN4 2.3237 | CDON 2.3231 | GRIN2B 2.2951 | RELN 2.2249 | SRD5A1 2.1992 | ROBO1 2.1673 | BBS2 2.0939 | GRIN2A 2.0931 | LRP6 2.0780 | GNG12 2.0311 | TACC1 2.0258 | TH 1.9742 | ATOH1 1.9203 | CEP120 1.8629 | AHSG 1.8397 | PAX6 1.6766 | HIF1A 1.6618 | LRP8 1.6538 | EMX2 1.6232 | VLDLR 1.6091 | TACC3 1.5959 | NPY 1.5849 | FGFR1 1.5730 | CDK5 1.5715 | NDEL1 1.5703 | BBS4 1.5605 | NDE1 1.5543 | FOXP3 1.5343 | MKKS 1.5151 | DICER1 1.4798 | ASCL1 1.4512 | POU3F2 1.4263 | PEX5 1.3972 | TSC1 1.3322 | CX3CR1 1.2922 | NF1 1.2913 | MDK 1.2489 | POU3F3 1.1996 | CCDC85C 1.1984 | GSK3B 1.1968 | ATG7 1.1390 | LHX6 1.0642 | PSEN1 1.0274 | WDR62 0.9405 | CDK5R1 0.9094 | EMX1 0.8875 | PAFAH1B1 0.8148 | NKX2-1 0.7775 | PEX13 0.7502 | DIXDC1 0.6947 | TFAP2C 0.6547 | SOX2 0.5800 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GTPase binding (boxplot) | 146 | 148 | 3.3475318616181786 | 4.076730731003009E-4 | 0.015590481832677498 | 0.0 | ABCA1 5.6064 | DIAPH3 5.2069 | BICD1 4.2108 | GGA3 3.6421 | DGKI 3.4965 | RILP 3.3070 | FMNL2 3.1102 | RANBP3 3.0390 | RIN3 2.7637 | PEX5L 2.5959 | DMXL2 2.5794 | ADCYAP1R1 2.5080 | MYRIP 2.4991 | DOCK9 2.4472 | RANBP2 2.4302 | NPC1L1 2.4288 | GGA2 2.4207 | FGD2 2.4194 | DOCK4 2.3990 | RABGAP1L 2.3243 | BIN1 2.3168 | CCDC64B 2.3109 | IPO7 2.2854 | RAP1A 2.2806 | SLC6A4 2.2725 | PARD6A 2.2550 | SYTL2 2.2517 | RAB11FIP4 2.2498 | RAB11FIP3 2.2486 | SRGAP1 2.2338 | DOCK2 2.2237 | ERC1 2.2200 | PRKCH 2.1900 | GNB1 2.1617 | DAAM2 2.1286 | NDRG1 2.0974 | NSF 2.0876 | KCTD13 2.0841 | FGD4 2.0673 | DOCK1 2.0545 | DIAPH2 2.0407 | RPH3AL 2.0392 | MYO5B 2.0328 | SGSM3 2.0210 | RAP1GAP 2.0128 | DOCK11 2.0111 | PLCE1 2.0072 | INF2 2.0071 | FGD5 1.9928 | CCDC64 1.9916 | RHOH 1.9833 | EXOC2 1.9693 | WDR44 1.9561 | CYFIP1 1.9503 | SYTL3 1.9442 | RIMS1 1.9395 | GIT1 1.9371 | FER 1.8987 | SPHK2 1.8974 | IPO5 1.8683 | EXPH5 1.8496 | RAPGEF6 1.8198 | DOCK5 1.7922 | RAP1B 1.7908 | PTPRN 1.7755 | GNB3 1.7560 | DOCK10 1.7553 | MAPKAP1 1.7541 | DOCK6 1.7289 | RAPGEF4 1.6971 | RPH3A 1.6628 | TNFAIP1 1.6556 | ALS2CL 1.6454 | CDC42EP5 1.6302 | CDC42BPB 1.6242 | RIMS2 1.5957 | MLPH 1.5851 | RHOBTB3 1.5845 | RASA1 1.5836 | MAP3K11 1.5775 | LRRK2 1.5730 | ARHGEF16 1.5691 | GOLGA4 1.5664 | NUP153 1.5486 | FGD6 1.5470 | BIRC5 1.5440 | PKN1 1.5412 | MAP2K1 1.5376 | GAS8 1.5288 | NOX1 1.5261 | RALBP1 1.5236 | DOCK3 1.5109 | TRIOBP 1.5023 | SYTL1 1.5004 | DAAM1 1.4884 | SYTL5 1.4883 | MARCH5 1.4717 | FGD3 1.4630 | DENND5A 1.4586 | DOCK8 1.4354 | RAB3A 1.4334 | DOCK7 1.4147 | FGD1 1.4085 | ANXA2 1.4037 | NCF2 1.3613 | DIAPH1 1.3602 | ALS2 1.3539 | CDC42EP2 1.3369 | RANBP10 1.3283 | RASGRP3 1.3202 | RANBP1 1.2934 | IQGAP1 1.2792 | DVL1 1.2676 | CDC42EP4 1.2590 | GOLGA5 1.1812 | ROCK1 1.1687 | RANBP9 1.1506 | KIF3B 1.1204 | ZFYVE20 1.1120 | VPS4A 1.0975 | HACE1 1.0906 | ARHGEF2 1.0873 | RGL3 1.0733 | IPO8 1.0311 | CDKL5 1.0190 | BICD2 0.9980 | PFN1 0.9787 | RAB3GAP1 0.9602 | SYTL4 0.9559 | NXT1 0.9369 | BNIP3 0.9338 | FLNA 0.9266 | RGPD8 0.9022 | IQGAP3 0.8907 | RTKN 0.8478 | GRASP 0.8192 | NOXA1 0.8155 | ARFIP2 0.7918 | CHM 0.7897 | FMNL1 0.7139 | STX4 0.6681 | ANXA2P2 0.6424 | ECT2 0.5904 | FMNL3 0.5546 | GNB2 0.5074 | RAB3D 0.4539 | DOCK10.2 | PIFO | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lamellipodium (boxplot) | 113 | 114 | 3.3474724587094022 | 4.0776045381352155E-4 | 0.015590481832677498 | 0.0 | PLEK2 4.4907 | CDH2 3.9744 | SPATA13 3.6908 | MYLK 3.2871 | NF2 3.2554 | PARVA 3.2150 | CTNNA3 3.1603 | APBB2 3.1052 | CTTN 3.0455 | PODXL 2.9223 | DGKZ 2.8053 | PTPRM 2.7283 | CCDC88A 2.7048 | IGF2BP1 2.5771 | SWAP70 2.5379 | APBB1IP 2.5101 | TIAM2 2.4489 | CSPG4 2.4209 | FGD2 2.4194 | INPPL1 2.4159 | APC2 2.3743 | CTNNA2 2.3669 | ARAP3 2.3645 | DPP4 2.3359 | PLD2 2.2800 | AMOT 2.2199 | WASF1 2.1938 | ABI1 2.1356 | AKT1 2.1144 | PIP5K1A 2.0835 | AIF1 2.0797 | SH3RF1 2.0775 | FGD4 2.0673 | TWF2 2.0553 | ITSN1 2.0433 | ARHGAP31 2.0298 | TRPV4 2.0262 | PSTPIP1 2.0118 | ACTR3 2.0099 | NEDD9 1.9952 | FGD5 1.9928 | PDPN 1.9883 | PKD2 1.9879 | CYFIP1 1.9503 | RAPH1 1.9311 | ANTXR1 1.9030 | FER 1.8987 | ENAH 1.8839 | SYNE2 1.8459 | PPP1R9B 1.8018 | PTPRO 1.7894 | MYO10 1.7867 | AKT2 1.7769 | PLD1 1.7651 | VIL1 1.7405 | ABI2 1.7385 | DPYSL3 1.7243 | BCAR1 1.6063 | STXBP2 1.6054 | PALLD 1.5733 | CDK5 1.5715 | TESC 1.5618 | FAT1 1.5616 | MCF2L 1.5518 | FGD6 1.5470 | PTPN13 1.5351 | APC 1.5096 | LRRC16A 1.5058 | NME2 1.4706 | FGD3 1.4630 | SNAP25 1.4539 | FGD1 1.4085 | PTK2 1.3822 | CTNNA1 1.3657 | VASP 1.3560 | AJUBA 1.3552 | ALS2 1.3539 | HAX1 1.3475 | FAP 1.3432 | SLC39A14 1.3358 | PIK3CA 1.3325 | TSC1 1.3322 | CAPZB 1.3059 | EVL 1.2888 | APBB1 1.2805 | CFL1 1.2636 | SSH1 1.2178 | ABI3 1.2170 | PLCG1 1.1759 | EPHA2 1.1715 | WASL 1.1528 | SLC39A6 1.1470 | RDX 1.1316 | PTK2B 1.1280 | PKN2 1.1257 | CTNND1 1.0729 | NRBP1 1.0691 | ARPC3 1.0531 | GSN 1.0374 | SPRY1 1.0270 | PXN 1.0115 | WASF2 0.9881 | CORO1A 0.9727 | RAB3IP 0.9465 | RAC3 0.8880 | DBNL 0.8579 | NCKAP1 0.8251 | PHACTR4 0.8203 | SCYL3 0.7809 | DAG1 0.6937 | ITGB1BP1 0.5811 | CTNNB1 0.5466 | PDXP 0.5140 | WASH3P | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of neurological system process (boxplot) | 49 | 50 | 3.336807826491957 | 4.237326175311473E-4 | 0.015684527039827166 | 0.0 | NRXN1 3.6097 | GRIA4 3.3765 | GRIK2 3.2889 | ERBB4 3.2809 | TNF 3.0639 | TNR 3.0413 | NR2E1 2.8955 | NLGN1 2.7866 | PRKCE 2.7354 | PLK2 2.4876 | OXTR 2.3881 | NPTN 2.3588 | GRIN2B 2.2951 | RNF10 2.2852 | RELN 2.2249 | LAMA2 2.2226 | SLC1A3 2.1895 | SHANK3 2.0446 | SNCA 1.9846 | PTGS2 1.9806 | RGS14 1.9785 | SLC24A2 1.9291 | OXT 1.9195 | GRIK1 1.8243 | PRKCZ 1.7929 | DLG4 1.7370 | KISS1R 1.7173 | IL6 1.7153 | SERPINE2 1.6272 | TAC1 1.6069 | NLGN3 1.5936 | ARRB2 1.4934 | CARTPT 1.4844 | DICER1 1.4798 | DRD1 1.4777 | GIP 1.4524 | LGI1 1.4430 | CRHR1 1.3545 | TACR1 1.3533 | CCKBR 1.3511 | ADORA2A 1.3027 | GFAP 1.2059 | PINK1 1.1846 | CHRNB2 0.9425 | NMU 0.8991 | IFNG 0.8931 | CCL2 0.6763 | NLGN2 0.6604 | HCRT 0.5645 | MRF | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
clathrin-coated vesicle (boxplot) | 192 | 192 | 3.3361305982819216 | 4.24766226533535E-4 | 0.015684527039827166 | 0.0 | VAMP1 4.1635 | PCLO 4.0360 | AQP2 4.0312 | PICALM 3.8576 | SYT9 3.5016 | ICA1 3.4698 | HIP1 3.4696 | AP3B1 3.4690 | AMPH 3.4482 | NCALD 3.4326 | FURIN 3.4013 | SPG21 3.0724 | ATP6V1G2-DDX39B 3.0639 | DNM2 3.0383 | EGFR 2.8090 | SLC18A3 2.7603 | VAMP3 2.7537 | STX1A 2.7012 | SYN2 2.6795 | SYT1 2.6792 | DMXL2 2.5794 | MYO1E 2.5057 | TRIM9 2.5012 | SLC6A17 2.4874 | SNAP91 2.4483 | SV2C 2.4442 | GGA2 2.4207 | ATP6V0D1 2.4205 | ECE1 2.4001 | AP1S1 2.3948 | RAB27B 2.3773 | TMEM163 2.3689 | SYNPR 2.3480 | MT3 2.3391 | BIN1 2.3168 | GRIN2B 2.2951 | CD207 2.2783 | SEPT5 2.2712 | CTTNBP2 2.2660 | SYTL2 2.2517 | GLP1R 2.2306 | CADM1 2.2215 | SYT12 2.2060 | AP2A1 2.2056 | SV2A 2.1873 | C16orf70 2.1433 | AP3B2 2.1374 | DENND1C 2.1267 | SLC18A2 2.0880 | SYN3 2.0801 | APBA1 2.0498 | SCYL2 2.0365 | SLC17A8 2.0171 | DTNBP1 2.0039 | OCRL 2.0031 | RAB3C 1.9941 | RAB35 1.9916 | WIPI1 1.9855 | CLVS1 1.9822 | SYT8 1.9767 | TH 1.9742 | GABBR1 1.9622 | AP1M1 1.9590 | SYPL1 1.9572 | MYO6 1.9297 | CYP19A1 1.9264 | AP1G1 1.9242 | LDLR 1.9157 | SYT17 1.9070 | SLC17A6 1.8970 | SYT4 1.8726 | LRP1 1.8683 | AP2A2 1.8451 | VTI1A 1.8430 | CLTCL1 1.8029 | SEPT6 1.7947 | PPT1 1.7921 | SLC17A7 1.7655 | TPRG1L 1.7652 | MLC1 1.7589 | ABCC8 1.7488 | STEAP2 1.7398 | SGIP1 1.7021 | BRSK1 1.7013 | MME 1.6938 | DOC2B 1.6682 | RPH3A 1.6628 | SYNGR2 1.6532 | AP1B1 1.6509 | SLC2A8 1.6424 | OTOF 1.6397 | SLC32A1 1.6305 | SV2B 1.6279 | EPN3 1.6090 | GOPC 1.6059 | DRD2 1.5853 | ATP7A 1.5814 | NPY1R 1.5788 | SEMA4C 1.5761 | LRRK2 1.5730 | SLC2A4 1.5730 | SNX9 1.5729 | GIPC1 1.5412 | DOC2A 1.5395 | TNK2 1.5282 | SYTL1 1.5004 | RAB3B 1.4934 | IGF2R 1.4885 | SH3BP4 1.4861 | TRAPPC4 1.4783 | SYN1 1.4729 | DAB2 1.4589 | CLTA 1.4478 | RAB3A 1.4334 | HIP1R 1.4332 | LDLRAP1 1.4279 | SYNGR1 1.4155 | CLINT1 1.4152 | SYT11 1.4142 | VWF 1.4032 | FAM109B 1.3985 | DDC 1.3973 | RGS19 1.3726 | LGI3 1.3710 | FCHO2 1.3684 | NECAP2 1.3674 | DENND1A 1.3576 | AP2S1 1.3442 | SNAPIN 1.3340 | STX6 1.3172 | CLN3 1.3063 | AP1M2 1.2846 | HSPA8 1.2788 | DNAJC5 1.2774 | CLTC 1.2691 | DVL2 1.2681 | DVL1 1.2676 | TYRP1 1.2671 | EPN2 1.2666 | GRIN1 1.2637 | SYT2 1.2635 | SYT7 1.2604 | APOB 1.2451 | SYT5 1.2326 | SYT3 1.2324 | GABRA2 1.2072 | NECAP1 1.2032 | SYNRG 1.2028 | ZNRF1 1.2006 | SVOP 1.1970 | RABAC1 1.1872 | SLC18A1 1.1645 | AFTPH 1.1535 | DENND1B 1.1516 | STXBP5 1.1492 | SORT1 1.1418 | SCAMP5 1.1254 | SLC40A1 1.1001 | MYLK2 1.0997 | SNX18 1.0994 | GAD1 1.0859 | VAMP2 1.0699 | MTMR2 1.0519 | CTLA4 1.0433 | SYT10 1.0421 | SYT6 1.0354 | FAM109A 1.0318 | CACFD1 1.0115 | CLVS2 1.0016 | AAK1 0.9958 | SLC30A3 0.9730 | SYTL4 0.9559 | GRIA2 0.9514 | CLTB 0.9372 | FCGR1A 0.9281 | PEBP1 0.9211 | GAD2 0.8924 | RASSF9 0.8752 | PIK3C2A 0.8669 | FCHO1 0.8604 | SYP 0.8425 | RAB14 0.7921 | TMED9 0.7869 | FCGR1B 0.7513 | TMED10 0.7281 | EPS15 0.7236 | SYPL2 0.7201 | SYNGR3 0.6909 | MALL 0.6023 | HCRT 0.5645 | AP1G2 0.4863 | SYT15 0.3848 | |||||||||||||||
calcium channel activity (boxplot) | 92 | 92 | 3.3341191290240615 | 4.2785000294487396E-4 | 0.015684527039827166 | 0.0 | PDE2A 3.7330 | RYR2 3.1737 | GRIN3A 3.1467 | CACNB4 3.1376 | CUL5 3.0470 | CACNA1G 3.0242 | RASA3 2.9238 | CACNA1C 2.8754 | GRM7 2.8268 | TRPM7 2.7626 | CACNG3 2.6709 | RYR3 2.5711 | TPCN2 2.5016 | CACNA1H 2.4410 | TRPM3 2.4127 | TRPM8 2.3742 | GPM6A 2.3326 | GRIN2B 2.2951 | CACNG4 2.2546 | CACNB2 2.2123 | TRPV1 2.1980 | JPH3 2.1788 | ITPR2 2.1594 | CACNA1D 2.1182 | CACNA1E 2.0970 | GRIN2A 2.0931 | CHRNA10 2.0484 | TRPV4 2.0262 | CACNA2D1 1.9982 | PKD2 1.9879 | GAS6 1.9676 | CACNA2D3 1.9648 | CYTH3 1.9639 | CACNG7 1.9540 | P2RX1 1.9501 | CACNA1A 1.9305 | HTR2B 1.9303 | SLC24A2 1.9291 | TRPM4 1.9153 | CATSPER1 1.8550 | CACNA1B 1.8481 | TMEM37 1.8371 | TRPM1 1.8355 | CACNG1 1.8336 | TPCN1 1.7668 | ITPR3 1.7657 | CATSPER4 1.7557 | TRPC7 1.7543 | ITGAV 1.7509 | TRPV3 1.7121 | CACNA2D2 1.6959 | CACNG6 1.6930 | CACNG5 1.6745 | PANX1 1.6650 | TRPM2 1.6363 | REST 1.6316 | TRPC4 1.6274 | CACNA1I 1.6100 | TRPC5 1.6072 | MCU 1.6010 | RYR1 1.5561 | TRPA1 1.5544 | CHRNA9 1.5108 | TRPV5 1.4897 | ITPR1 1.4342 | TRPC6 1.4311 | CACNA2D4 1.4192 | MS4A2 1.4184 | CACNA1S 1.3954 | FKBP1A 1.3770 | CACNG2 1.3692 | TRPC3 1.3214 | FKBP1B 1.3101 | CACNG8 1.2699 | GRIN1 1.2637 | CACNB1 1.1775 | TRPV2 1.1404 | JPH2 1.1317 | FGF2 1.1278 | TRPM6 1.0811 | GRIN3B 1.0627 | CATSPER3 1.0602 | CLCA3P 1.0301 | PSEN1 1.0274 | CACFD1 1.0115 | TRPC1 0.9629 | CACNA1F 0.9583 | CACNB3 0.7536 | CALHM1 0.6965 | CATSPER2 0.6702 | TRPV6 0.5852 | ORAI1 0.5808 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
thymic T cell selection (boxplot) | 18 | 18 | 3.331791684344114 | 4.3144410476214645E-4 | 0.015684527039827166 | 0.0 | HLA-DMA 4.6143 | FAS 3.2882 | CARD11 3.1018 | ITPKB 2.8294 | GLI3 2.3270 | CCR7 2.3166 | DOCK2 2.2237 | JAG2 2.1763 | CD28 2.1569 | CD3D 2.1205 | CD3E 2.1205 | MINK1 1.4611 | PTPRC 1.4182 | ZAP70 1.3847 | SHH 1.2438 | SPN 1.2252 | SRF 1.1778 | CD74 1.0390 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cyclic nucleotide metabolic process (boxplot) | 50 | 51 | 3.3285941168892674 | 4.364275377928273E-4 | 0.015684527039827166 | 0.0 | PDE2A 3.7330 | ADCY10 3.5194 | PDE10A 3.5081 | PDE4B 3.1574 | PDE8A 3.0407 | CNP 2.9419 | PDE11A 2.9328 | PDE4D 2.8834 | GUCY2D 2.6485 | GUCY2C 2.6418 | PDE7B 2.6103 | PTHLH 2.5819 | ADCY2 2.5386 | GUCY1B3 2.5107 | GUCY1A3 2.4867 | RORA 2.4266 | PDE3A 2.3821 | PDE1C 2.1963 | ADCY3 2.1650 | GUCY1A2 1.9560 | HTR2B 1.9303 | CALCRL 1.8557 | ADM 1.7485 | ADCY9 1.7405 | ADCY1 1.7392 | AQP1 1.7153 | ADCY8 1.7139 | PDE3B 1.7081 | NPPC 1.5320 | ADCY4 1.4548 | NUDT4 1.4402 | PDE4C 1.4334 | ADCY7 1.4224 | PDE8B 1.3712 | NPR1 1.3340 | ADORA2A 1.3027 | PDE7A 1.2485 | GUCY2F 1.2384 | PTH 1.2270 | GNAS 1.1857 | PDE1B 1.1847 | GUCA2B 1.1846 | PDE5A 1.1185 | NPPA 1.0642 | NPPB | NPR2 0.9581 | RAMP2 0.9523 | HTR2C 0.9475 | UCN2 0.7722 | ADCY6 0.7536 | PDE4A 0.7502 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
female gonad development (boxplot) | 90 | 93 | 3.325806399735999 | 4.408157077033792E-4 | 0.01572135436378621 | 0.0 | SIRT1 7.4176 | PCYT1B 7.2283 | TIPARP 3.3907 | ARID5B 3.1718 | FANCA 3.1547 | SOHLH1 3.0802 | VEGFA 3.0488 | ROBO2 3.0085 | AMH 2.9749 | ADAMTS1 2.9721 | SLIT2 2.8500 | CHAT 2.7603 | FGF7 2.5131 | IQCJ-SCHIP1 2.4652 | SLIT3 2.4489 | MSH4 2.4326 | FSHR 2.4105 | FST 2.4000 | SCHIP1 2.3967 | VGF 2.3948 | PLA2G4A 2.3298 | AGT 2.2659 | NRIP1 2.1803 | BCL2 2.1766 | CCND2 2.1625 | ACSBG1 2.1597 | FOXL2 2.1573 | FOXO3 2.0675 | WNT10B 2.0180 | IMMP2L 1.9821 | MMP14 1.9618 | ZFP42 1.9444 | DMC1 1.9224 | BMPR1B 1.9013 | NR5A1 1.8809 | EDN2 1.8797 | ESR1 1.8508 | ESR2 1.8459 | AFP 1.7611 | LHCGR 1.7607 | EIF2B4 1.7419 | CAPN5 1.7012 | STRA8 1.6857 | ICAM1 1.6718 | ANG 1.6605 | PDGFRA 1.6489 | NOS3 1.6288 | INHBA 1.6220 | KDR 1.5543 | MMP19 1.5508 | STAT5A 1.5114 | FANCG 1.4995 | CASP2 1.4160 | LEP 1.4143 | KITLG 1.3781 | CTNNA1 1.3657 | BMP15 1.3595 | NOBOX 1.3482 | SFRP1 1.2842 | UBE3A 1.2776 | BRCA2 1.2712 | TAF4 1.2681 | EIF2B5 1.2665 | PGR 1.2410 | FSHB 1.2331 | FOXC1 1.2136 | PLEKHA1 1.2069 | LHX9 1.1994 | LFNG 1.1848 | ANGPT1 1.1416 | INHBB 1.1310 | ERMP1 1.1105 | BMP4 1.1081 | ADRBK1 1.0662 | STAT5B 1.0063 | GPR149 0.9780 | WNT4 0.9772 | INHA 0.8631 | SOD1 0.8543 | SGPL1 0.8268 | WNT10A 0.8239 | BCL2L1 0.8053 | EREG 0.8038 | FZD4 0.7448 | SPO11 0.6482 | AHR 0.6079 | CENPI 0.4883 | CCNE1 0.4397 | EIF2B2 0.2862 | KGFLP2 0.1912 | A6NF36 | KGFLP1 | estrogen receptor | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of nitric oxide biosynthetic process (boxplot) | 44 | 45 | 3.3255416447831743 | 4.412345806383833E-4 | 0.01572135436378621 | 0.0 | GLA 3.9934 | CAV1 3.7656 | INSR 3.1624 | TNF 3.0639 | OPRM1 2.8228 | EGFR 2.8090 | DDAH2 2.7706 | PTX3 2.6077 | KLRK1 2.5472 | HSP90AA1 2.5357 | EDN1 2.3459 | DDAH1 2.3427 | HBB 2.2562 | AGTR2 2.2307 | TRPV1 2.1980 | AKT1 2.1144 | AIF1 2.0797 | NOS1AP 2.0268 | PKD2 1.9879 | PTGS2 1.9806 | INS 1.9742 | IL1B 1.8813 | ESR1 1.8508 | ARG2 1.7953 | HRH1 1.7853 | AKT2 1.7769 | IL6 1.7153 | ICAM1 1.6718 | IL4 1.6202 | P2RX4 1.5095 | GIMAP5 1.4739 | JAK2 1.4043 | TLR2 1.3663 | HSP90AB1 1.1735 | TSPO 1.1685 | SOD2 1.1214 | AGXT2 1.0963 | ACP5 1.0359 | TLR4 0.9855 | CD34 0.9161 | TICAM1 0.9140 | IFNG 0.8931 | IL10 0.8668 | PTGIS 0.8316 | HSP90AA2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of dendrite development (boxplot) | 57 | 57 | 3.319251784149294 | 4.5129503413365857E-4 | 0.01586350745882774 | 0.0 | DCC 5.1066 | PTPRD 3.6941 | KALRN 3.6105 | RAP2A 3.0635 | CAMK1 2.9695 | NR2E1 2.8955 | NLGN1 2.7866 | PDLIM5 2.6326 | YWHAH 2.6079 | PTPRF 2.5339 | TNIK 2.5237 | CAMK1D 2.4333 | BCL11A 2.3352 | KNDC1 2.2520 | CAMK2B 2.2519 | RELN 2.2249 | ROBO1 2.1673 | NUMBL 2.1296 | RHOC 2.1005 | CDC20 2.0817 | SHANK3 2.0446 | IL1RAPL1 2.0206 | ACTR3 2.0099 | NEDD4 1.9836 | SRCIN1 1.9663 | LPAR1 1.8285 | ANAPC2 1.7859 | KIAA0319 1.7454 | PALM 1.7163 | RAPGEF4 1.6971 | EPHA4 1.6721 | LRP8 1.6538 | VLDLR 1.6091 | BMP7 1.5842 | LRRK2 1.5730 | CDK5 1.5715 | CAPRIN1 1.5227 | LZTS1 1.4506 | SEMA4D 1.3860 | SMAD1 1.3854 | PTEN 1.3846 | NGEF 1.3111 | EFNA1 1.2501 | CHRNA3 1.1921 | ARF6 1.1563 | MET 1.1441 | ILK 1.1347 | SIPA1L1 1.1047 | CAPRIN2 1.0754 | NUMB 1.0524 | DBN1 1.0367 | CDKL5 1.0190 | CHRNB2 0.9425 | ACHE 0.9394 | BMP5 0.9345 | CDK5R1 0.9094 | TLX2 0.7068 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cellular component maintenance (boxplot) | 37 | 37 | 3.315486839413881 | 4.574182428680462E-4 | 0.015963896676094814 | 0.007194244604316547 | GPR98 4.6366 | PCDH15 3.5572 | ERCC6 3.3262 | BBS1 3.1352 | CDH23 2.9737 | KIFC3 2.9206 | MPZ 2.7198 | CNGB1 2.5546 | CLRN1 2.3729 | RP1 2.3145 | PARD6A 2.2550 | MAK 2.1724 | SHROOM2 2.1572 | PLEKHA7 2.1105 | BBS2 2.0939 | USH2A 2.0822 | PROM1 1.9541 | TULP1 1.9365 | ABCA4 1.9148 | MYOCD 1.8480 | TANC1 1.7362 | CAMSAP3 1.6054 | BBS4 1.5605 | MKKS 1.5151 | RDH12 1.4615 | CLN8 1.4407 | USH1C 1.4192 | NPHP3 1.3038 | SUPV3L1 1.2808 | CSF1R 1.2307 | CDHR1 1.1424 | MTMR2 1.0519 | RP1L1 1.0340 | BBS10 0.9907 | IQCB1 0.9071 | USH1G 0.8160 | NLGN2 0.6604 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of insulin receptor signaling pathway (boxplot) | 27 | 28 | 3.3067439891726673 | 4.7193555802471643E-4 | 0.01635373855679975 | 0.007142857142857143 | SIRT1 7.4176 | INPP5K 3.5378 | PRKCB 2.9939 | PID1 2.9916 | SIK2 2.5468 | PTPRF 2.5339 | INPPL1 2.4159 | GRB10 2.0523 | SOCS1 1.9877 | IGF2 1.9742 | INS | IRS1 1.9115 | IL1B 1.8813 | AHSG 1.8397 | PRKCZ 1.7929 | RELA 1.6587 | PTPRE 1.6062 | PRKCQ 1.5129 | GRB14 1.4400 | PTPN1 1.4205 | LEP 1.4143 | RPS6KB1 1.2260 | GSK3A 1.2130 | ENPP1 1.1901 | SOCS3 1.1324 | TSC2 1.0731 | PRKCD 1.0164 | OGT 0.6705 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cholesterol transport (boxplot) | 30 | 32 | 3.305451487387585 | 4.7411758885818056E-4 | 0.01635373855679975 | 0.0070921985815602835 | SIRT1 7.4176 | ABCA1 5.6064 | APOA1 3.0248 | APOC3 | SREBF2 2.9595 | APOA4 2.5911 | NFKBIA 2.3376 | EGF 2.1937 | PTCH1 2.1082 | ABCG1 2.0741 | LRP1 1.8683 | PLA2G10 1.7764 | PPARG 1.6692 | CETP 1.6214 | PON1 1.5922 | ABCG5 1.4958 | ABCG8 1.4958 | NFKB1 1.4613 | APOE 1.4398 | LEP 1.4143 | ABCA2 1.4115 | LAMTOR1 1.3465 | APOC1 1.3441 | APOC2 | ADIPOQ 1.3289 | NR1H3 1.3265 | LIPG 1.3223 | SHH 1.2438 | TSPO 1.1685 | NR1H2 1.1632 | IRAK1 1.0945 | APOA2 0.8951 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of sterol transport (boxplot) | 30 | 32 | 3.305451487387585 | 4.7411758885818056E-4 | 0.01635373855679975 | 0.0070921985815602835 | SIRT1 7.4176 | ABCA1 5.6064 | APOA1 3.0248 | APOC3 | SREBF2 2.9595 | APOA4 2.5911 | NFKBIA 2.3376 | EGF 2.1937 | PTCH1 2.1082 | ABCG1 2.0741 | LRP1 1.8683 | PLA2G10 1.7764 | PPARG 1.6692 | CETP 1.6214 | PON1 1.5922 | ABCG5 1.4958 | ABCG8 1.4958 | NFKB1 1.4613 | APOE 1.4398 | LEP 1.4143 | ABCA2 1.4115 | LAMTOR1 1.3465 | APOC1 1.3441 | APOC2 | ADIPOQ 1.3289 | NR1H3 1.3265 | LIPG 1.3223 | SHH 1.2438 | TSPO 1.1685 | NR1H2 1.1632 | IRAK1 1.0945 | APOA2 0.8951 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
response to lipoprotein stimulus (boxplot) | 13 | 13 | 3.301246886785849 | 4.8128070734065886E-4 | 0.01635373855679975 | 0.006993006993006993 | ABCA1 5.6064 | CDH13 3.9298 | SREBF2 2.9595 | MMP9 2.7841 | ABCG1 2.0741 | CCL5 1.8122 | PPARG 1.6692 | NOS3 1.6288 | ADAM17 1.5056 | CD36 1.4667 | F3 1.2282 | HMGCS1 1.2125 | NPC1 0.9459 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
axon terminus (boxplot) | 64 | 66 | 3.300132041479251 | 4.831967413809757E-4 | 0.01635373855679975 | 0.006944444444444444 | SEPT7 4.3221 | GRIK4 3.9399 | GHRH 3.4507 | AMPH 3.4482 | GRIA4 3.3765 | CHRM4 3.3170 | GRIK2 3.2889 | PTPRN2 2.8388 | SYNJ2 2.7782 | SLC18A3 2.7603 | SNCG 2.4359 | ATP6V0D1 2.4205 | KCNC4 2.3714 | BIN1 2.3168 | GRIN2B 2.2951 | PRSS12 2.2794 | SEPT5 2.2712 | PCSK1 2.1639 | GRIN2A 2.0931 | SLC18A2 2.0880 | CCKAR 2.0865 | GRIK3 2.0041 | TH 1.9742 | CHRM3 1.9459 | OPRD1 1.9420 | SNCB 1.9380 | CYP19A1 1.9264 | OXT 1.9195 | CHRM2 1.8694 | P2RX7 1.8574 | ESR1 1.8508 | DRD4 1.8319 | GRIK1 1.8243 | DBH 1.8135 | SEPT6 1.7947 | TANC1 1.7362 | PFN2 1.7072 | ADORA1 1.7070 | DPYSL2 1.6469 | SLC32A1 1.6305 | DRD2 1.5853 | HCN4 1.5579 | P2RX4 1.5095 | GOT1 1.4481 | P2RX3 1.3783 | GRIN1 1.2637 | ILK 1.1347 | CABP4 1.1126 | MYLK2 1.0997 | CRHBP 1.0855 | CHRM1 1.0409 | HAP1 1.0381 | AAK1 0.9958 | CAD 0.9730 | GRIA2 0.9514 | CCK 0.9390 | PEBP1 0.9211 | NMU 0.8991 | OPHN1 0.8605 | UCN 0.8158 | CALCA 0.8098 | KCNC3 0.8056 | DIXDC1 0.6947 | L1CAM 0.6002 | DKFZp586I031 | estrogen receptor | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
triglyceride metabolic process (boxplot) | 82 | 82 | 3.2938560532165377 | 4.941154645203838E-4 | 0.01653594629894928 | 0.006896551724137931 | SIRT1 7.4176 | LPIN2 5.2136 | CAV1 3.7656 | APOC3 3.0248 | LPCAT1 3.0227 | ELOVL6 2.9754 | PRKACB 2.9293 | GPD1 2.7351 | ACLY 2.7017 | PPP1CB 2.6090 | APOA5 2.5911 | AGPAT4 2.5633 | ABHD5 2.5629 | GPAT2 2.5064 | ELOVL2 2.4805 | MOGAT3 2.4686 | CAV3 2.3881 | PCK1 2.3007 | ACSL1 2.2283 | SLC27A5 2.1872 | LPIN1 2.1486 | ELOVL1 2.0817 | ACSL5 2.0627 | AGPAT6 2.0214 | AGPAT2 2.0126 | SLC22A4 1.9862 | LPL 1.9485 | ELOVL7 1.9273 | MOGAT1 1.9020 | GPX1 1.8947 | ALMS1 1.8311 | CPS1 1.8058 | SLC25A1 1.8029 | PNPLA2 1.7743 | PRKACG 1.7616 | AGPAT3 1.7230 | GK 1.7138 | DGAT1 1.7111 | ACSL6 1.6845 | AGPAT5 1.6333 | LIPF 1.6322 | PNPLA3 1.6241 | CETP 1.6214 | ACSL3 1.6086 | LIPC 1.6053 | AGPAT1 1.5913 | NKX2-3 1.5542 | HSD17B12 1.5489 | TECR 1.5086 | PNLIPRP2 1.4930 | PCSK9 1.4808 | MGLL 1.4752 | APOE 1.4398 | GPAM 1.4378 | DGAT2 1.4198 | CYP2E1 1.3837 | PLIN1 1.3583 | APOC1 1.3441 | FABP4 1.3200 | PPP1CA 1.3052 | ACSL4 1.2837 | APOB 1.2451 | APOH 1.2376 | MTTP 1.2284 | LIPE 1.1888 | FASN 1.1849 | CPT1A 1.1834 | CEL 1.1461 | ELOVL4 1.1167 | INSIG2 1.0701 | GPD1L 1.0398 | PPP1CC 1.0164 | MOGAT2 0.9999 | APOA2 0.8951 | ELOVL5 0.8407 | ACACA 0.8142 | PRKACA 0.6979 | CAT 0.6876 | AGPAT9 0.6685 | INSIG1 0.6516 | ELOVL3 0.6419 | G6PC 0.6297 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AMP binding (boxplot) | 30 | 30 | 3.2866881297530104 | 5.068651749624564E-4 | 0.016847232958275934 | 0.00684931506849315 | PDE2A 3.7330 | PRKAG2 3.7137 | PDE10A 3.5081 | APRT 3.0059 | PDE11A 2.9328 | PDE4D 2.8834 | RAPGEF3 2.6418 | CNGB1 2.5546 | PDE3A 2.3821 | HCN1 2.2865 | FBP1 2.2674 | PDE1C 2.1963 | PYGL 2.1612 | PRKAR1B 2.1387 | HCN2 2.0858 | CNGA2 1.8158 | PRKAR2B 1.7791 | PDE3B 1.7081 | RAPGEF4 1.6971 | HCN4 1.5579 | PRKAR1A 1.3889 | PRKAR2A 1.3064 | AKAP7 1.2143 | PFKM 1.1142 | PRKAG1 1.1069 | PYGM 1.1008 | ACSS2 1.1005 | CNGA4 0.8741 | HCN3 0.8529 | ACSS1 0.6104 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
renal system development (boxplot) | 183 | 186 | 3.2859669215384777 | 5.081647213326379E-4 | 0.016847232958275934 | 0.006802721088435374 | AQP2 4.0312 | HES1 3.7965 | NIPBL 3.6793 | SULF2 3.5216 | MAGI2 3.4637 | TIPARP 3.3907 | PCSK5 3.2644 | DLL1 3.2607 | PKHD1 3.2472 | ARID5B 3.1718 | ACTA2 3.1316 | ZBTB16 3.0880 | TP63 3.0850 | VEGFA 3.0488 | ASS1 3.0221 | ROBO2 3.0085 | ADAMTS1 2.9721 | SULF1 2.9550 | PODXL 2.9223 | TINAG 2.9207 | PROX1 2.8868 | SOX8 2.8542 | KIF26B 2.8387 | ODC1 2.8365 | BASP1 2.7554 | PRKX 2.6609 | MYO1E 2.5057 | SOX9 2.4914 | IQCJ-SCHIP1 2.4652 | SERPINF1 2.4022 | SCHIP1 2.3967 | ACAT1 2.3578 | INVS 2.3332 | GLI3 2.3270 | SLC12A1 2.3097 | AGT 2.2659 | FGF1 2.2613 | RBP4 2.2565 | COL4A3 2.2501 | FSTL3 2.2464 | FOXD3 2.2443 | AGTR2 2.2307 | WNT11 2.1927 | NPHS2 2.1857 | HMGCS2 2.1809 | BCL2 2.1766 | STAT1 2.1689 | LRP4 2.1606 | BAG6 2.1586 | TP73 2.1456 | PECAM1 2.1136 | PTCH1 2.1082 | ALDH1A2 2.0957 | ACVR2B 2.0747 | EYA1 2.0489 | WNT9B 2.0446 | NID1 2.0430 | MEF2C 2.0426 | VANGL2 2.0307 | PLCE1 2.0072 | PKD2 1.9879 | HNF1B 1.9806 | PROM1 1.9541 | ITGA8 1.9537 | RET 1.9319 | AGTR1 1.9300 | BMP6 1.8906 | GPC3 1.8708 | TEK 1.8630 | WNT7B 1.8583 | MYOCD 1.8480 | FOXF1 1.8463 | UPK3A 1.8418 | PAX2 1.8357 | SMO 1.8103 | FGF8 1.7956 | PTPRO 1.7894 | LEF1 1.7470 | WWTR1 1.7412 | OSR2 1.6982 | MME 1.6938 | ID2 1.6791 | PYGO1 1.6713 | GREM1 1.6695 | COL4A4 1.6590 | PDGFRA 1.6489 | NKX3-1 1.6263 | HNF1A 1.6105 | SOX11 1.6081 | SMAD4 1.6061 | TSHZ3 1.5963 | ALDH9A1 1.5934 | WFS1 1.5881 | BMP7 1.5842 | ARL3 1.5835 | SIX2 1.5825 | LRRK2 1.5730 | GATA3 1.5648 | JAG1 1.5613 | STRA6 1.5142 | APC 1.5096 | NPHS1 1.4983 | LAMB2 1.4979 | ZNF354A 1.4877 | PCSK9 1.4808 | WT1 1.4801 | HES5 1.4456 | ANGPT2 1.4272 | CALB1 1.4175 | FOXC2 1.4158 | SMAD1 1.3854 | RDH10 1.3839 | RPGRIP1L 1.3825 | WNT5A 1.3655 | GLI2 1.3606 | OVOL1 1.3428 | C1GALT1 1.3390 | TSC1 1.3322 | ADIPOQ 1.3289 | HAS2 1.3278 | MTSS1 1.3065 | NOTCH3 1.2976 | PYGO2 1.2933 | NF1 1.2913 | IRX3 1.2900 | IQGAP1 1.2792 | KLHL3 1.2450 | SHH 1.2438 | PDGFRB 1.2307 | BCL2L11 1.2301 | HEYL 1.2247 | FOXC1 1.2136 | LHX1 1.2133 | POU3F3 1.1996 | UMOD 1.1937 | TFAP2A 1.1936 | ALDH1A3 1.1799 | GDNF 1.1771 | FOXS1 1.1734 | SALL1 1.1703 | KCNJ8 1.1442 | ANGPT1 1.1416 | GDF11 1.1226 | TGFBR1 1.1193 | BMP4 1.1081 | ENPEP 1.0886 | TET2 1.0774 | TCF21 1.0756 | REN 1.0696 | APH1A 1.0646 | WNT6 1.0632 | JMJD6 1.0466 | CITED1 1.0397 | SPRY1 1.0270 | PDGFB 1.0240 | DCN 1.0126 | CTSH 0.9922 | AHI1 0.9870 | WNT4 0.9772 | OSR1 0.9759 | ID3 0.9709 | LGR4 0.9329 | AQP11 0.9209 | FOXD1 0.9206 | CD34 0.9161 | PTCD2 0.9115 | PKD1 0.8841 | RRM2B 0.8716 | SOX17 0.8386 | SOX4 0.8314 | SGPL1 0.8268 | MPV17 0.8158 | SIX1 0.8071 | ACE 0.7753 | TFAP2B 0.7079 | FGF10 0.7055 | PAX8 0.6248 | CTNNB1 0.5466 | EGR1 0.5440 | SIX4 0.4859 | CEP290 0.3855 | CA2 0.3746 | HYAL2 0.2244 | CD24 | RALDH2 | RP5-1049G16.1 | |||||||||||||||||||||
sensory perception of mechanical stimulus (boxplot) | 120 | 124 | 3.282871224292206 | 5.137779691917199E-4 | 0.01684777958034056 | 0.006756756756756757 | COL11A2 4.6854 | GPR98 4.6366 | OTOA 3.7072 | FYN 3.7055 | NIPBL 3.6793 | PCDH15 3.5572 | NAV2 3.4966 | HEXA 3.0328 | OTOS 3.0083 | CDH23 2.9737 | ATP2B2 2.8342 | GRM7 2.8268 | KCNQ4 2.8155 | ASIC2 2.7474 | BARHL1 2.7381 | SNAI2 2.6919 | KCNQ1 2.5850 | CLRN1 2.3729 | OTOR 2.3610 | HEXB 2.3391 | CASP3 2.3272 | GRIN2B 2.2951 | COL4A3 2.2501 | TMPRSS3 2.2184 | TRPV1 2.1980 | SLC1A3 2.1895 | ATP6V1B1 2.1332 | MYO3A 2.1330 | USH2A 2.0822 | GABRA5 2.0812 | EYA1 2.0489 | CHRNA10 2.0484 | LOXHD1 2.0404 | SLC17A8 2.0171 | AXIN1 1.9756 | TH 1.9742 | SOBP 1.9633 | DRGX 1.9621 | MYC 1.9575 | LHFPL5 1.9424 | MYO6 1.9297 | GPX1 1.8947 | GRXCR1 1.8854 | TBL1X 1.8800 | TBX1 1.8661 | SPTBN4 1.8647 | KCNE1 1.8416 | ALMS1 1.8311 | AQP4 1.8231 | ALDH7A1 1.8048 | GJB3 1.7960 | TPRN 1.7859 | PAX3 1.7479 | EML2 1.7347 | HPN 1.7202 | GABRB2 1.7081 | TIMM10 1.7062 | IL18 1.7039 | MYO7A 1.7012 | CLIC5 1.6546 | ATP6V0A4 1.6520 | OTOF 1.6397 | MARVELD2 1.6375 | SERPINE2 1.6272 | MYO1A 1.6056 | TSHZ3 1.5963 | WFS1 1.5881 | TMC1 1.5815 | FGFR1 1.5730 | SLC26A4 1.5569 | TRPA1 1.5544 | MKKS 1.5151 | CHRNA9 1.5108 | CRYM 1.5098 | KPTN 1.4933 | ZNF354A 1.4877 | COL1A1 1.4835 | PGAP1 1.4486 | COL11A1 1.4339 | RAB3A 1.4334 | ESPN 1.4330 | USH1C 1.4192 | CEACAM16 1.3793 | DIAPH1 1.3602 | LRTOMT 1.3465 | COCH 1.3375 | POU4F2 1.3305 | COL2A1 1.3191 | TIMM9 1.3046 | GJB2 1.2907 | POU4F3 1.2812 | HOXA1 1.2096 | TMIE 1.2034 | TFAP2A 1.1936 | FBXO11 1.1877 | NDUFB9 1.1686 | NDP 1.1646 | TECTA 1.1635 | SLC26A5 1.1553 | CDKN1B 1.1519 | DFNA5 1.1301 | GJB6 1.1136 | MYCBPAP 1.0619 | CHD7 1.0210 | SLC12A2 0.9968 | SPRY2 0.9548 | CHRNB2 0.9425 | SOD1 0.8543 | USH1G 0.8160 | WDR1 0.8122 | SIX1 0.8071 | MYO15A 0.7632 | FZD4 0.7448 | TIMM8B 0.7168 | GJC3 0.7123 | TBX18 0.6120 | TIMM13 0.6015 | SOX2 0.5800 | POU3F4 0.4645 | STRC 0.4507 | OTOG | PJVK | RFT2 | WHRN | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of actin filament-based process (boxplot) | 163 | 170 | 3.2779045629906207 | 5.229037389768987E-4 | 0.017032717790940843 | 0.006711409395973154 | CRK 4.9972 | ARHGEF10 3.8915 | ARAP1 3.7330 | CCL24 3.7243 | ACTR3B 3.7214 | INPP5K 3.5378 | PARK2 3.3357 | NF2 3.2554 | FES 3.1088 | ARPC4 2.9695 | SYNPO 2.9309 | PROX1 2.8868 | SLIT2 2.8500 | BAIAP2 2.7979 | SPTBN1 2.7693 | SPTAN1 2.7684 | PRKCE 2.7354 | EPHA3 2.7107 | CCDC88A 2.7048 | EPB49 2.6804 | FZD10 2.6723 | JAM3 2.6353 | SPTBN2 2.5986 | CXCL12 2.5696 | EPHA1 2.5465 | ADD1 2.5292 | SPTBN5 2.4987 | TACSTD2 2.4154 | SERPINF2 2.4022 | CAV3 2.3881 | SORBS3 2.3613 | EDN1 2.3459 | CCR7 2.3166 | FHOD1 2.2999 | DLC1 2.2963 | SCN5A 2.2668 | AMOT 2.2199 | WNT11 2.1927 | ARHGAP6 2.1854 | EPHA5 2.1737 | SHROOM2 2.1572 | ACTR3C 2.1470 | SMAD3 2.1433 | CCL26 2.1094 | RHOC 2.1005 | NEB 2.0865 | LIMA1 2.0815 | ROCK2 2.0790 | SEMA3E 2.0638 | TWF2 2.0553 | EFNA5 2.0515 | MEF2C 2.0426 | VANGL2 2.0307 | ACTR3 2.0099 | MAP3K1 1.9924 | TWF1 1.9582 | MYBPC3 1.9461 | FER 1.8987 | RHOA 1.8947 | CAPZA2 1.8696 | LRP1 1.8683 | SPTBN4 1.8647 | TEK 1.8630 | DLG1 1.8617 | TNNC1 1.8440 | CAPZA1 1.8250 | ADD2 1.7611 | ABL2 1.7537 | MTOR 1.7516 | VIL1 1.7405 | CELSR1 1.7341 | MYLK3 1.7219 | DAPK3 1.7213 | KISS1R 1.7173 | ARPC1A 1.7079 | ARPC1B | PFN2 1.7072 | BAIAP2L1 1.6951 | SCIN 1.6737 | PDGFRA 1.6489 | CDC42EP5 1.6302 | F2RL1 1.6183 | TAC1 1.6069 | TPM1 1.5971 | RASA1 1.5836 | KANK1 1.5829 | CDK5 1.5715 | PTGER4 1.5596 | MLST8 1.5439 | PDGFA 1.5347 | PRKCQ 1.5129 | TRIOBP 1.5023 | EP300 1.4888 | HCK 1.4790 | NCK2 1.4470 | MYO1F 1.4447 | ABL1 1.4403 | ARHGEF10L 1.4113 | VILL 1.3837 | BAG4 1.3675 | GPM6B 1.3610 | TACR1 1.3533 | CDC42EP2 1.3369 | TSC1 1.3322 | SCN1B 1.3219 | CAPZB 1.3059 | CCL11 1.3027 | JMY 1.2927 | CNN2 1.2907 | TMSB10 1.2904 | SDC4 1.2900 | ARHGEF15 1.2884 | SFRP1 1.2842 | PLEK 1.2748 | SPTA1 1.2678 | RICTOR 1.2609 | CCL21 1.2605 | NCKAP1L 1.2593 | DSTN 1.2412 | CSF1R 1.2307 | PDGFRB 1.2307 | ARPC5L 1.2241 | SSH1 1.2178 | AVIL 1.2074 | PPM1F 1.1863 | LIMK1 1.1825 | ROCK1 1.1687 | ARF6 1.1563 | RHOQ 1.1486 | PAK1 1.1424 | ILK 1.1347 | RDX 1.1316 | PTK2B 1.1280 | TMSB15B 1.1148 | SSH3 1.1031 | MYLK2 1.0997 | SPTB 1.0618 | ARPC3 1.0531 | SCN2B 1.0517 | GSN 1.0374 | TMSB15A 1.0351 | S1PR1 1.0347 | PRKCD 1.0164 | CAPG 0.9758 | CORO1A 0.9727 | CTGF 0.9616 | ARHGEF19 0.9428 | WASH2P 0.9218 | CDK5R1 0.9094 | LATS1 0.8990 | GPR65 0.8893 | PAK3 0.8800 | TMSB4X 0.8266 | GRHL3 0.8241 | PHPT1 0.8227 | SSH2 0.7923 | PPM1E 0.7885 | ARPC5 0.7879 | NCK1 0.7460 | DIXDC1 0.6947 | PDXP 0.5140 | ARPC2 0.4034 | WASH1 0.2959 | CAPZA3 0.2266 | FRAP1 | TMSB4Y | TMSL4 | WASH3P | WASH4P | WASH6P | |||||||||||||||||||||||||||||||||||||
positive regulation of transmission of nerve impulse (boxplot) | 47 | 47 | 3.2759438322232795 | 5.26547511132236E-4 | 0.017037822115179502 | 0.006666666666666667 | NRXN1 3.6097 | GRIA4 3.3765 | GRIK2 3.2889 | ERBB4 3.2809 | TNF 3.0639 | TNR 3.0413 | NR2E1 2.8955 | NLGN1 2.7866 | PRKCE 2.7354 | PLK2 2.4876 | OXTR 2.3881 | NPTN 2.3588 | GRIN2B 2.2951 | RELN 2.2249 | LAMA2 2.2226 | SLC1A3 2.1895 | SHANK3 2.0446 | SNCA 1.9846 | PTGS2 1.9806 | RGS14 1.9785 | SLC24A2 1.9291 | OXT 1.9195 | GRIK1 1.8243 | PRKCZ 1.7929 | DLG4 1.7370 | KISS1R 1.7173 | IL6 1.7153 | SERPINE2 1.6272 | TAC1 1.6069 | NLGN3 1.5936 | ARRB2 1.4934 | CARTPT 1.4844 | DRD1 1.4777 | GIP 1.4524 | LGI1 1.4430 | CRHR1 1.3545 | TACR1 1.3533 | CCKBR 1.3511 | ADORA2A 1.3027 | GFAP 1.2059 | PINK1 1.1846 | CHRNB2 0.9425 | NMU 0.8991 | IFNG 0.8931 | CCL2 0.6763 | NLGN2 0.6604 | HCRT 0.5645 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of nitric oxide biosynthetic process (boxplot) | 33 | 34 | 3.273554184404674 | 5.310201318385888E-4 | 0.017069502395811478 | 0.006622516556291391 | INSR 3.1624 | TNF 3.0639 | OPRM1 2.8228 | EGFR 2.8090 | DDAH2 2.7706 | PTX3 2.6077 | KLRK1 2.5472 | HSP90AA1 2.5357 | EDN1 2.3459 | DDAH1 2.3427 | HBB 2.2562 | AGTR2 2.2307 | TRPV1 2.1980 | AKT1 2.1144 | AIF1 2.0797 | PKD2 1.9879 | PTGS2 1.9806 | INS 1.9742 | IL1B 1.8813 | ESR1 1.8508 | HRH1 1.7853 | AKT2 1.7769 | IL6 1.7153 | ICAM1 1.6718 | P2RX4 1.5095 | JAK2 1.4043 | TLR2 1.3663 | HSP90AB1 1.1735 | SOD2 1.1214 | AGXT2 1.0963 | TLR4 0.9855 | TICAM1 0.9140 | IFNG 0.8931 | HSP90AA2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cell proliferation in forebrain (boxplot) | 25 | 25 | 3.2722368104997375 | 5.335008181701628E-4 | 0.017069502395811478 | 0.006578947368421052 | ARX 6.2843 | FABP7 3.0449 | TACC2 2.8635 | FGFR2 2.7650 | HMGA2 2.5708 | GLI3 2.3270 | NCOR2 2.2598 | PCM1 2.2454 | NUMBL 2.1296 | WNT7A 2.0616 | HHEX 2.0321 | DCT 2.0319 | TACC1 2.0258 | CEP120 1.8629 | WNT3A 1.6407 | EMX2 1.6232 | TACC3 1.5959 | FGFR1 1.5730 | POU3F2 1.4263 | LHX5 1.2164 | ZEB2 1.2160 | POU3F3 1.1996 | NUMB 1.0524 | HOOK3 0.9990 | DIXDC1 0.6947 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of neurogenesis (boxplot) | 117 | 117 | 3.269596270577991 | 5.385054080528917E-4 | 0.017085307946405382 | 0.006535947712418301 | NTRK3 4.8124 | HES1 3.7965 | PTPRD 3.6941 | SCARF1 3.2573 | VEGFA 3.0488 | CDH4 3.0350 | ROBO2 3.0085 | ASPA 2.8861 | SOX8 2.8542 | SLIT2 2.8500 | TIAM1 2.8400 | OPRM1 2.8228 | NTRK2 2.7766 | PLXNB2 2.7490 | DLL3 2.7304 | EPHB2 2.7088 | XRCC6 2.5915 | DSCAM 2.5746 | CXCL12 2.5696 | PTPRF 2.5339 | SERPINF1 2.4022 | NPTN 2.3588 | BCL11A 2.3352 | GLI3 2.3270 | RTN4 2.3237 | TNFRSF12A 2.3109 | FOXG1 2.2887 | NGFR 2.2572 | MAP1B 2.2447 | OTP 2.2004 | STK25 2.1927 | PRKCH 2.1900 | ROBO1 2.1673 | FXN 2.1599 | TP73 2.1456 | TRIM32 2.1399 | NUMBL 2.1296 | WNT3 2.0876 | LIG4 2.0575 | TWF2 2.0553 | SHANK3 2.0446 | NGF 2.0438 | DCT 2.0319 | ISLR2 2.0308 | IL1RAPL1 2.0206 | DISC1 2.0102 | ACTR3 2.0099 | RGS14 1.9785 | GRM5 1.9765 | RHOA 1.8947 | SMO 1.8103 | NKX6-2 1.8055 | XRCC5 1.7960 | ANAPC2 1.7859 | ID2 1.6791 | PAX6 1.6766 | NOTCH1 1.6712 | PPARG 1.6692 | HIF1A 1.6618 | RELA 1.6587 | WNT3A 1.6407 | XRCC4 1.6336 | SERPINE2 1.6272 | SOX11 1.6081 | LYN 1.5986 | DRD2 1.5853 | BMP2 1.5776 | NDEL1 1.5703 | VEGFC 1.5569 | ADNP 1.5371 | CAPRIN1 1.5227 | XRCC2 1.5169 | EP300 1.4888 | LIF 1.4805 | DICER1 1.4798 | AMIGO1 1.4658 | ASCL1 1.4512 | PLAG1 1.4461 | SEMA4D 1.3860 | SMAD1 1.3854 | CXCR4 1.2607 | SHH 1.2438 | SMARCD3 1.2326 | NTN1 1.2089 | GFAP 1.2059 | SOX10 1.2019 | LIMK1 1.1825 | ZNF488 1.1776 | NKX6-1 1.1771 | STK11 1.1724 | TSPO 1.1685 | MET 1.1441 | TRPV2 1.1404 | PRPF19 1.1381 | ILK 1.1347 | CLCF1 1.0800 | CAPRIN2 1.0754 | NUMB 1.0524 | CDKL5 1.0190 | NTF3 0.9832 | NKX2-2 0.9814 | PRKCI 0.9445 | HDAC2 0.9044 | CNTF 0.8746 | SPEN 0.8488 | PAFAH1B1 0.8148 | OLIG2 0.8085 | ACE 0.7753 | SKIL 0.7578 | SEMA7A 0.7223 | DIXDC1 0.6947 | PLXNB1 0.6552 | ARHGDIA 0.6161 | SYNJ1 0.6101 | SOX2 0.5800 | SNW1 0.5348 | MAPT 0.4387 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
neuron migration (boxplot) | 86 | 86 | 3.2668785204805153 | 5.437016530902561E-4 | 0.017138879206445107 | 0.006493506493506494 | ARX 6.2843 | DCC 5.1066 | NTRK3 4.8124 | YWHAE 4.5001 | FYN 3.7055 | MARK1 3.3006 | APBB2 3.1052 | DAB1 2.9720 | FEZF1 2.8875 | SPOCK1 2.7896 | NTRK2 2.7766 | SEMA6A 2.7685 | BARHL1 2.7381 | CXCL12 2.5696 | PRKG1 2.4878 | DCLK1 2.3698 | GPM6A 2.3326 | PCNT 2.3313 | MNX1 2.3035 | CNTN2 2.2820 | RELN 2.2249 | DYX1C1 2.1759 | DNER 2.1720 | TWIST1 2.0979 | CCKAR 2.0865 | NAV1 2.0665 | DISC1 2.0102 | GAS6 1.9676 | DRGX 1.9621 | NR2F2 1.9601 | ATOH1 1.9203 | DCX 1.8681 | ESR2 1.8459 | KIAA0319 1.7454 | CELSR1 1.7341 | PEX7 1.6864 | CELSR3 1.6843 | PAX6 1.6766 | LMX1B 1.6731 | FZD3 1.6473 | CHL1 1.6315 | MARK2 1.6028 | FGFR1 1.5730 | CDK5 1.5715 | NDEL1 1.5703 | ROBO3 1.5671 | NRCAM 1.5362 | CELSR2 1.5268 | GJA1 1.5265 | MYH10 1.4980 | ASCL1 1.4512 | MDGA1 1.4403 | DCDC2 1.4344 | AXL 1.4159 | PEX5 1.3972 | PTK2 1.3822 | NDN 1.3688 | NDNF 1.3563 | SATB2 1.3530 | TBX20 1.3377 | ITGA3 1.3270 | LHX1 1.2133 | NTN1 1.2089 | NEUROG2 1.1811 | SRF 1.1778 | MET 1.1441 | BARHL2 1.1224 | NEUROD4 1.0811 | PSEN1 1.0274 | CDKL5 1.0190 | CCR4 0.9511 | CCK 0.9390 | CDK5R1 0.9094 | KATNA1 0.8990 | TLX3 0.8937 | NR2F1 0.8323 | PAFAH1B1 0.8148 | NKX2-1 0.7775 | TUBB2B 0.7654 | PEX13 0.7502 | PEX2 0.6819 | GFRA3 0.6517 | VAX1 0.6258 | NR4A2 0.6229 | TOP2B 0.6174 | PHOX2B 0.4915 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of calcium ion transport via voltage-gated calcium channel activity (boxplot) | 47 | 47 | 3.263276761444174 | 5.506595573314677E-4 | 0.017246939725138147 | 0.0064516129032258064 | CACNB4 3.1376 | CACNA1C 2.8754 | OPRM1 2.8228 | CACNG3 2.6709 | PKD2L1 2.5895 | CXCL12 2.5696 | TPCN2 2.5016 | SESTD1 2.4004 | VDR 2.3912 | CAV3 2.3881 | AGT 2.2659 | CACNG4 2.2546 | NKX2-5 2.2385 | GLP1R 2.2306 | CACNB2 2.2123 | CACNA1D 2.1182 | RHOC 2.1005 | CACNA1E 2.0970 | CCKAR 2.0865 | IL1RAPL1 2.0206 | CACNA2D1 1.9982 | PKD2 1.9879 | GAS6 1.9676 | CACNG7 1.9540 | OPRD1 1.9420 | CACNA1A 1.9305 | CACNA1B 1.8481 | CACNG1 1.8336 | DRD4 1.8319 | ITGAV 1.7509 | CACNG6 1.6930 | CACNG5 1.6745 | NCS1 1.6216 | CACNA1I 1.6100 | ADRB1 1.6047 | DRD2 1.5853 | RYR1 1.5561 | CACNA1S 1.3954 | CACNG2 1.3692 | ADORA2A 1.3027 | CACNG8 1.2699 | CACNB1 1.1775 | ADRA2A 1.1742 | ADRB2 1.0467 | CACNA1F 0.9583 | CACNB3 0.7536 | GNAI2 0.5640 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PDZ domain binding (boxplot) | 84 | 85 | 3.2623623820613656 | 5.52439020252482E-4 | 0.017246939725138147 | 0.00641025641025641 | KCNJ12 5.2371 | AQP2 4.0312 | USHBP1 3.6661 | DMD 3.6492 | MAGI2 3.4637 | PARK2 3.3357 | LLGL2 3.3024 | GRIK2 3.2889 | DLG2 3.2580 | KCNJ4 3.2311 | GRID2 3.0003 | LPAR2 2.8343 | ATP2B2 2.8342 | GRM7 2.8268 | SYNJ2 2.7782 | FZD10 2.6723 | LNX2 2.5189 | FZD1 2.4363 | DOCK4 2.3990 | ATP2B4 2.2998 | SNTG2 2.2762 | CADM1 2.2215 | ERC1 2.2200 | CXADR 2.1888 | FZD7 2.1227 | NSF 2.0876 | APBA1 2.0498 | NOS1AP 2.0268 | SLC22A4 1.9862 | SLC22A5 1.9715 | SNTB1 1.9473 | NCOA2 1.9449 | EXOC4 1.9205 | LPAR1 1.8285 | SMO 1.8103 | FZD2 1.8049 | DLG4 1.7370 | FZD6 1.7328 | SLC22A12 1.7065 | TGFBR3 1.7014 | PLEKHA2 1.6788 | FZD3 1.6473 | CCDC88C 1.6398 | SDC2 1.6349 | ADRB1 1.6047 | IGSF5 1.5909 | LNX1 1.5820 | ARHGEF16 1.5691 | GIPC1 1.5412 | GJA1 1.5265 | ADAM17 1.5056 | SFRP4 1.4173 | DLG3 1.3998 | PTEN 1.3846 | CFTR 1.3770 | MPP3 1.3729 | TBC1D10A 1.3510 | SFRP1 1.2842 | FZD5 1.2625 | ACVR2A 1.2534 | PLEKHA1 1.2069 | CLCN3 1.1673 | PDZK1 1.1602 | GRIA1 1.1475 | SSTR2 1.1051 | SLC9A3R2 1.0731 | FZD9 1.0715 | PSEN1 1.0274 | SFRP5 1.0088 | MUC17 0.9758 | SRR 0.9038 | CRIPT 0.8965 | GRASP 0.8192 | FRZB 0.8133 | FZD8 0.7752 | SFRP2 0.7657 | FZD4 0.7448 | SLC9A3R1 0.7026 | LIN7C 0.6405 | L1CAM 0.6002 | CXXC4 0.5706 | SNTA1 0.5644 | KCNJ18 0.4591 | GPR34 0.3195 | PROSAPIP1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of DNA damage response, signal transduction by p53 class mediator (boxplot) | 25 | 25 | 3.2445635603228427 | 5.881538095897643E-4 | 0.018188098187693597 | 0.006369426751592357 | SIRT1 7.4176 | PLA2R1 3.4416 | CDKN2A 3.0353 | ANKRD1 2.9349 | SNAI2 2.6919 | KDM1A 2.5909 | CD44 2.4166 | MIF 2.1324 | TWIST1 2.0979 | SPRED1 1.9968 | PMAIP1 1.7492 | SETD8 1.6968 | SPRED2 1.6370 | DYRK1A 1.6138 | EEF1E1 1.6050 | ATM 1.6025 | MSX1 1.4876 | HIC1 1.4290 | SMYD2 1.4219 | SNAI1 1.3990 | PSMD10 1.2562 | CD74 1.0390 | ATR 0.8945 | MDM2 0.7327 | DDX5 0.3221 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ion channel inhibitor activity (boxplot) | 18 | 19 | 3.2444765278374277 | 5.883335732581596E-4 | 0.018188098187693597 | 0.006329113924050633 | KCNJ12 5.2371 | KCNA5 3.3453 | GNB2L1 3.0025 | STX1A 2.7012 | KCNMB2 2.6357 | NEDD4L 2.3099 | PDZD3 2.1882 | SLC30A1 2.0329 | TNNI3 2.0145 | NEDD4 1.9836 | AMBP 1.6978 | PRPF18 1.6616 | RASA1 1.5836 | SCN1B 1.3219 | ENSA 1.3018 | KCNV1 1.1761 | RSC1A1 0.9429 | PHPT1 0.8227 | ANKRD36C | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
channel inhibitor activity (boxplot) | 18 | 19 | 3.2444765278374277 | 5.883335732581596E-4 | 0.018188098187693597 | 0.006329113924050633 | KCNJ12 5.2371 | KCNA5 3.3453 | GNB2L1 3.0025 | STX1A 2.7012 | KCNMB2 2.6357 | NEDD4L 2.3099 | PDZD3 2.1882 | SLC30A1 2.0329 | TNNI3 2.0145 | NEDD4 1.9836 | AMBP 1.6978 | PRPF18 1.6616 | RASA1 1.5836 | SCN1B 1.3219 | ENSA 1.3018 | KCNV1 1.1761 | RSC1A1 0.9429 | PHPT1 0.8227 | ANKRD36C | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cyclic nucleotide biosynthetic process (boxplot) | 90 | 91 | 3.2442380692091546 | 5.888263644099334E-4 | 0.018188098187693597 | 0.00625 | ABCA1 5.6064 | ADORA3 4.1949 | PDE2A 3.7330 | GHRH 3.4507 | GRM8 3.2143 | GNAL 3.0690 | GNG7 2.8840 | GRM7 2.8268 | OPRM1 2.8228 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | GUCY1A3 2.4867 | HTR1B 2.3684 | MC1R 2.3626 | EDN1 2.3459 | ADORA2B 2.3294 | GABBR2 2.2343 | GLP1R 2.2306 | PDZD3 2.1882 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | GABBR1 1.9622 | DRD3 1.9435 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | DRD4 1.8319 | ADCYAP1 1.8068 | CAP1 1.7921 | EDNRB 1.7889 | LHCGR 1.7607 | ADM 1.7485 | MTNR1A 1.7179 | PALM 1.7163 | RAF1 1.7090 | GHRHR 1.6541 | NOS3 1.6288 | ADRB1 1.6047 | DRD2 1.5853 | P2RY11 1.5469 | ADNP 1.5371 | NPPC 1.5320 | INSL3 1.5247 | APLP1 1.4983 | DRD1 1.4777 | RAMP1 1.4694 | GNAI3 1.4435 | NPR3 1.4425 | APOE 1.4398 | OXER1 1.4362 | ADCY7 1.4224 | MRAP 1.4047 | LTB4R2 1.3819 | CRHR1 1.3545 | MC5R 1.3486 | NPR1 1.3340 | GRM3 1.3280 | GALR1 1.3255 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | ADRA2A 1.1742 | CCR2 1.1711 | CALCR 1.1467 | MC4R 1.1026 | GRM2 1.0960 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | GALR3 0.8839 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | GNAI2 0.5640 | HCTR-6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis (boxplot) | 20 | 20 | 3.2434076213295633 | 5.905455206010046E-4 | 0.018188098187693597 | 0.006211180124223602 | SIRT1 7.4176 | MSH2 3.2026 | HIPK2 3.1565 | TP63 3.0850 | BBC3 2.6870 | USP28 2.2572 | BAG6 2.1586 | TP73 2.1456 | PPP2R5C 1.8424 | RPS27L 1.5118 | EP300 1.4888 | AEN 1.4179 | PML 1.3600 | TP53 1.3523 | PHLDA3 1.3045 | BRCA2 1.2712 | C16orf5 1.2594 | BCL3 1.1329 | IFI16 0.9032 | DYRK2 0.6555 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
photoreceptor cell maintenance (boxplot) | 25 | 25 | 3.2371090541282337 | 6.037362937268975E-4 | 0.018188098187693597 | 0.006172839506172839 | GPR98 4.6366 | PCDH15 3.5572 | ERCC6 3.3262 | BBS1 3.1352 | CDH23 2.9737 | CNGB1 2.5546 | CLRN1 2.3729 | RP1 2.3145 | MAK 2.1724 | BBS2 2.0939 | USH2A 2.0822 | PROM1 1.9541 | TULP1 1.9365 | ABCA4 1.9148 | BBS4 1.5605 | MKKS 1.5151 | RDH12 1.4615 | CLN8 1.4407 | USH1C 1.4192 | NPHP3 1.3038 | CDHR1 1.1424 | RP1L1 1.0340 | BBS10 0.9907 | IQCB1 0.9071 | USH1G 0.8160 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of action potential (boxplot) | 101 | 102 | 3.236182817352468 | 6.056988606049085E-4 | 0.018188098187693597 | 0.006134969325153374 | MPP5 5.2324 | SCN3B 4.2468 | ARHGEF10 3.8915 | SCN2A 3.6519 | CNR2 3.3995 | GRIK2 3.2889 | ERBB2 3.2295 | MBP 3.0687 | HEXA 3.0328 | CACNA1G 3.0242 | NFASC 2.9513 | ASPA 2.8861 | KCNIP1 2.8571 | KCNMB2 2.6357 | JAM3 2.6353 | PMP22 2.6336 | SCN9A 2.5308 | NAB1 2.5233 | SBF2 2.4546 | KCNMB3 2.4149 | CAV3 2.3881 | HEXB 2.3391 | GRIN2B 2.2951 | CNTN2 2.2820 | SCN5A 2.2668 | SKI 2.1799 | ADRA1A 2.1619 | SCN8A 2.1612 | ACSBG1 2.1597 | NDRG1 2.0974 | GRIN2A 2.0931 | QKI 2.0538 | ERCC2 2.0521 | PRX 2.0418 | P2RX1 1.9501 | KCNMB4 1.9400 | EGR2 1.8938 | AFG3L2 1.8657 | P2RX7 1.8574 | LPAR1 1.8285 | NKX6-2 1.8055 | PLLP 1.7913 | GNAQ 1.7558 | EIF2B4 1.7419 | ADAM22 1.7197 | TAC1 1.6069 | CNR1 1.6061 | NAB2 1.5795 | PPARD 1.5657 | MYO5A 1.5529 | GJD2 1.5523 | P2RX4 1.5095 | CD9 1.5036 | GPC1 1.4900 | DICER1 1.4798 | DRD1 1.4777 | SMAD7 1.4674 | AMIGO1 1.4658 | HES5 1.4456 | GLRA1 1.4443 | POU3F2 1.4263 | PLP1 1.4162 | PTEN 1.3846 | P2RX3 1.3783 | TACR1 1.3533 | LGI4 1.3508 | MAL 1.3433 | GNA11 1.3379 | TSC1 1.3322 | SCN1B 1.3219 | CHRNA1 1.3109 | CLN3 1.3063 | NF1 1.2913 | KCND2 1.2892 | EIF2B5 1.2665 | CNTNAP1 1.2662 | CXCR4 1.2607 | KLK6 1.2520 | GNPAT 1.2058 | CHRNA4 1.2001 | CHRNB4 1.1921 | GAL3ST1 1.1795 | ILK 1.1347 | ID4 1.1089 | SCN2B 1.0517 | DHH 0.9994 | NTF3 0.9832 | TGFB1 0.9693 | POU3F1 0.9537 | CHRNB2 0.9425 | SRI 0.8747 | SOD1 0.8543 | KCNJ10 0.8338 | UGT8 0.8186 | OLIG2 0.8085 | FOXA2 0.8073 | ZNF24 0.7153 | GJC3 0.7123 | DAG1 0.6937 | CLDN11 0.6198 | EIF2B2 0.2862 | MRF | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
voltage-gated cation channel activity (boxplot) | 130 | 130 | 3.222235370091577 | 6.359730033822508E-4 | 0.018832509663791984 | 0.006097560975609756 | KCNJ12 5.2371 | SCN3B 4.2468 | SCN2A 3.6519 | KCND3 3.5097 | KCNA5 3.3453 | KCNMA1 3.3055 | KCNA7 3.2839 | KCNJ4 3.2311 | CACNB4 3.1376 | KCNJ5 3.0325 | CACNA1G 3.0242 | KCNQ5 2.9323 | CACNA1C 2.8754 | GRM7 2.8268 | KCNQ4 2.8155 | CACNG3 2.6709 | SCN11A 2.6313 | KCNQ1 2.5850 | KCNH1 2.5742 | SCN9A 2.5308 | TPCN2 2.5016 | CACNA1H 2.4410 | KCNC4 2.3714 | KCNH5 2.3674 | HCN1 2.2865 | SCN5A 2.2668 | KCNH7 2.2610 | CACNG4 2.2546 | KCNE2 2.2438 | KCNH8 2.2162 | CACNB2 2.2123 | KCNQ3 2.2037 | SCN8A 2.1612 | CACNA1D 2.1182 | CACNA1E 2.0970 | GRIN2A 2.0931 | HCN2 2.0858 | KCNAB1 2.0747 | KCNJ6 2.0282 | KCNK18 2.0117 | CACNA2D1 1.9982 | PKD2 1.9879 | GAS6 1.9676 | CACNA2D3 1.9648 | CACNG7 1.9540 | CACNA1A 1.9305 | KCNB2 1.9269 | KCNT2 1.9253 | KCNT1 1.9150 | KCNAB2 1.9081 | KCNA2 1.8775 | KCNC1 1.8772 | SCN1A 1.8708 | CATSPER1 1.8550 | CACNA1B 1.8481 | KCNE1 1.8416 | CACNG1 1.8336 | KCNK1 1.8306 | GRIK1 1.8243 | KCNIP2 1.8243 | KCNH2 1.8168 | KCNC2 1.8152 | ITGAV 1.7509 | KCNA1 1.7305 | CACNG6 1.6930 | CACNG5 1.6745 | KCNJ3 1.6361 | REST 1.6316 | KCNB1 1.6104 | CACNA1I 1.6100 | SCN10A 1.5853 | SCN7A 1.5790 | HCN4 1.5579 | RYR1 1.5561 | NOX1 1.5261 | SNAP25 1.4539 | KCNAB3 1.4270 | KCNA6 1.4115 | CACNA1S 1.3954 | KCNJ16 1.3936 | SCN3A 1.3785 | GRIN2D 1.3766 | KCNJ14 1.3766 | CACNG2 1.3692 | KCNA10 1.3288 | SCN1B 1.3219 | KCNG3 1.2978 | KCNJ1 1.2945 | KCND2 1.2892 | KCNG2 1.2727 | CACNG8 1.2699 | KCNG4 1.2667 | HVCN1 1.2377 | KCNQ2 1.2247 | SCN4B 1.2124 | KCNK2 1.1962 | KCNK6 1.1799 | CACNB1 1.1775 | KCNV1 1.1761 | KCNS1 1.1656 | KCNE4 1.1563 | KCNJ11 1.1557 | KCNS2 1.1460 | KCNJ8 1.1442 | FGF2 1.1278 | KCNF1 1.1068 | KCNJ2 1.0875 | KCNH4 1.0789 | KCNU1 1.0750 | KCNV2 1.0713 | SCN2B 1.0517 | KCNH3 1.0368 | KCNS3 1.0343 | KCNJ15 1.0099 | KCNG1 0.9673 | CACNA1F 0.9583 | HCN3 0.8529 | KCNJ10 0.8338 | SCN4A 0.8170 | KCNC3 0.8056 | KCNE3 0.7603 | CACNB3 0.7536 | KCNA3 0.7220 | KCNA4 0.6180 | KCND1 0.5914 | KCNH6 0.5251 | KCNJ9 0.4817 | KCNJ18 0.4591 | KCNJ13 0.4431 | KCNK3 0.3093 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
female sex differentiation (boxplot) | 106 | 109 | 3.2213590214866397 | 6.379210694960058E-4 | 0.018832509663791984 | 0.006060606060606061 | SIRT1 7.4176 | PCYT1B 7.2283 | TIPARP 3.3907 | ARID5B 3.1718 | FANCA 3.1547 | TP63 3.0850 | SOHLH1 3.0802 | VEGFA 3.0488 | ROBO2 3.0085 | AMH 2.9749 | ADAMTS1 2.9721 | SLIT2 2.8500 | DACH2 2.8064 | CHAT 2.7603 | TBX3 2.6289 | FGF7 2.5131 | ADCYAP1R1 2.5080 | IQCJ-SCHIP1 2.4652 | SLIT3 2.4489 | MSH4 2.4326 | FSHR 2.4105 | FST 2.4000 | SCHIP1 2.3967 | VGF 2.3948 | PLA2G4A 2.3298 | AGT 2.2659 | RBP4 2.2565 | SRD5A1 2.1992 | NRIP1 2.1803 | BCL2 2.1766 | CCND2 2.1625 | ACSBG1 2.1597 | FOXL2 2.1573 | FOXO3 2.0675 | WNT10B 2.0180 | IMMP2L 1.9821 | MMP14 1.9618 | ZFP42 1.9444 | DMC1 1.9224 | BMPR1B 1.9013 | NR5A1 1.8809 | EDN2 1.8797 | ESR1 1.8508 | ESR2 1.8459 | AFP 1.7611 | LHCGR 1.7607 | EIF2B4 1.7419 | NCOA3 1.7202 | CAPN5 1.7012 | STRA8 1.6857 | ICAM1 1.6718 | ANG 1.6605 | PDGFRA 1.6489 | NOS3 1.6288 | INHBA 1.6220 | KDR 1.5543 | MMP19 1.5508 | STRA6 1.5142 | STAT5A 1.5114 | FANCG 1.4995 | CASP2 1.4160 | LEP 1.4143 | KITLG 1.3781 | CTNNA1 1.3657 | WNT5A 1.3655 | BMP15 1.3595 | NOBOX 1.3482 | SFRP1 1.2842 | UBE3A 1.2776 | BRCA2 1.2712 | TAF4 1.2681 | EIF2B5 1.2665 | PGR 1.2410 | FSHB 1.2331 | FOXC1 1.2136 | PLEKHA1 1.2069 | LHX9 1.1994 | LFNG 1.1848 | ANGPT1 1.1416 | INHBB 1.1310 | ERMP1 1.1105 | BMP4 1.1081 | MED1 1.0961 | ADRBK1 1.0662 | CHD7 1.0210 | STAT5B 1.0063 | GPR149 0.9780 | WNT4 0.9772 | TGFB1 0.9693 | INHA 0.8631 | SOD1 0.8543 | SGPL1 0.8268 | WNT10A 0.8239 | BCL2L1 0.8053 | EREG 0.8038 | NKX2-1 0.7775 | ACVR1B 0.7753 | FZD4 0.7448 | FGF10 0.7055 | CAT 0.6876 | SPO11 0.6482 | AHR 0.6079 | CENPI 0.4883 | CCNE1 0.4397 | EIF2B2 0.2862 | KGFLP2 0.1912 | A6NF36 | KGFLP1 | estrogen receptor | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cell junction organization (boxplot) | 165 | 165 | 3.2146301493800427 | 6.530634483167264E-4 | 0.019106994062727697 | 0.006024096385542169 | MPP5 5.2324 | KRT5 4.3271 | HEG1 4.0972 | CDH2 3.9744 | CDH13 3.9298 | TAOK2 3.3686 | NF2 3.2554 | PARVA 3.2150 | ACTN3 3.1352 | CLDN23 3.1016 | CDH4 3.0350 | CDH18 2.9750 | RSU1 2.9709 | NFASC 2.9513 | KIFC3 2.9206 | LAMA3 2.9086 | TLN2 2.8514 | CDH12 2.8169 | PTPRK 2.7450 | MPZ 2.7198 | SNAI2 2.6919 | PARVB 2.6643 | LAMA5 2.3426 | CLDN9 2.3109 | NLGN4X 2.3043 | DLC1 2.2963 | PARD6A 2.2550 | LIM2 2.2345 | ARL2 2.2292 | CADM1 2.2215 | AMOT 2.2199 | MPP7 2.2168 | WNT11 2.1927 | CXADR 2.1888 | ARHGAP6 2.1854 | BCL2 2.1766 | SHROOM2 2.1572 | SMAD3 2.1433 | ACTB 2.1337 | NUMBL 2.1296 | CDH6 2.1282 | CRB3 2.1267 | PLEKHA7 2.1105 | MARVELD3 2.1095 | RHOC 2.1005 | PIP5K1A 2.0835 | CLDN1 2.0629 | PARD3 2.0430 | ACTN1 2.0386 | CLDN15 2.0275 | TRPV4 2.0262 | CLDN18 2.0192 | LAMB3 2.0178 | CDH11 1.9918 | LAMC1 1.9271 | ACTG1 1.9056 | JUP 1.9019 | RHOA 1.8947 | STRN 1.8799 | DLG1 1.8617 | TBCD 1.8480 | LAMC2 1.8307 | DSG1 1.8240 | CDH8 1.8008 | PARD6G 1.7998 | GJA4 1.7960 | PTPRO 1.7894 | CD151 1.7743 | FBF1 1.7617 | CADM3 1.7482 | CLDN12 1.7433 | PIP5K1C 1.7353 | PVR 1.7307 | ACTN2 1.7215 | CDH24 1.7171 | PVRL2 1.7152 | VCL 1.7125 | HNF4A 1.7052 | GJA5 1.6874 | CDH5 1.6622 | SORBS1 1.6523 | MARVELD2 1.6375 | CDH10 1.6369 | TNS1 1.6163 | CAMSAP3 1.6054 | CLDN14 1.5897 | FLNC 1.5869 | TGFB2 1.5799 | TESK2 1.5784 | OCLN 1.5772 | PARD6B 1.5688 | PVRL1 1.5566 | LIMS1 1.5517 | GJA1 1.5265 | APC 1.5096 | CD9 1.5036 | CCM2 1.4998 | FERMT2 1.4965 | INADL 1.4898 | SMAD7 1.4674 | COL17A1 1.4533 | PDPK1 1.4292 | LIMS2 1.3778 | CLDN20 1.3757 | CLDN22 1.3696 | TRIP6 1.3664 | CTNNA1 1.3657 | VASP 1.3560 | AJUBA 1.3552 | CADM2 1.3494 | CDH7 1.3419 | MTDH 1.3350 | DST 1.3319 | PLEC 1.3309 | GJB2 1.2907 | HDAC7 1.2885 | VMP1 1.2691 | CNTNAP1 1.2662 | KRT14 1.2615 | CSF1R 1.2307 | TJP1 1.2276 | FRMPD2 1.2268 | CDH1 1.2150 | GNPAT 1.2058 | SRF 1.1778 | CLDN17 1.1407 | ILK 1.1347 | PTK2B 1.1280 | PKN2 1.1257 | ITGB1 1.1192 | CDC42 1.0907 | CLDN19 1.0776 | CTNND1 1.0729 | CDH15 1.0574 | NUMB 1.0524 | MLLT4 1.0402 | DSP 1.0262 | PXN 1.0115 | TGFB3 1.0107 | GJB1 0.9815 | CDH9 0.9768 | TLN1 0.9695 | TGFB1 0.9693 | RAMP2 0.9523 | PRKCI 0.9445 | GJC1 0.9440 | CDH3 0.9414 | PVRL4 0.9395 | FLNA 0.9266 | PVRL3 0.9077 | ITGB4 0.8918 | RAB8B 0.8841 | ITGA6 0.8763 | ITGA5 0.8380 | UGT8 0.8186 | ZNF703 0.7049 | NLGN2 0.6604 | ARHGEF6 0.6228 | F11R 0.6028 | THY1 0.6002 | ECT2 0.5904 | GJD3 0.5757 | CTNNB1 0.5466 | FBLIM1 0.5285 | TESK1 0.5194 | ||||||||||||||||||||||||||||||||||||||||||
rhythmic process (boxplot) | 186 | 188 | 3.2135133772350586 | 6.556084494415693E-4 | 0.019106994062727697 | 0.005988023952095809 | SIRT1 7.4176 | PCYT1B 7.2283 | AANAT 3.6243 | GHRH 3.4507 | FAS 3.2882 | HTR7 3.2865 | ERBB2 3.2295 | GRIN3A 3.1467 | SOHLH1 3.0802 | VEGFA 3.0488 | NFIL3 3.0212 | ROBO2 3.0085 | GNB2L1 3.0025 | AMH 2.9749 | ADAMTS1 2.9721 | SLIT2 2.8500 | CHAT 2.7603 | RBM4 2.6896 | RBM4B 2.6896 | MSTN 2.6651 | PER3 2.6258 | FGF7 2.5131 | TIMP4 2.4753 | IQCJ-SCHIP1 2.4652 | SLIT3 2.4489 | MSH4 2.4326 | FSHR 2.4105 | TIMELESS 2.4009 | SCHIP1 2.3967 | VGF 2.3948 | OXTR 2.3881 | PLA2G4A 2.3298 | GRIN2B 2.2951 | ENOX1 2.2738 | SLC6A4 2.2725 | AGT 2.2659 | KCNH7 2.2610 | NPAS2 2.2608 | SRD5A1 2.1992 | NRIP1 2.1803 | BCL2 2.1766 | NCOR1 2.1739 | CCND2 2.1625 | FOXL2 2.1573 | GDF10 2.1481 | CST3 2.1381 | DBP 2.1014 | GRIN2A 2.0931 | NR3C1 2.0926 | FOXO3 2.0675 | EGR3 2.0474 | TEF 2.0331 | IMMP2L 1.9821 | TH 1.9742 | MMP14 1.9618 | TYRO3 1.9521 | DRD3 1.9435 | PHLPP1 1.9389 | DMC1 1.9224 | BMPR1B 1.9013 | EGR2 1.8938 | ARNTL 1.8895 | JUN 1.8868 | NR5A1 1.8809 | EDN2 1.8797 | PRKAA2 1.8703 | CCRN4L 1.8630 | ESR1 1.8508 | ESR2 1.8459 | ALB 1.8309 | ANXA1 1.8032 | AFP 1.7611 | LHCGR 1.7607 | EIF2B4 1.7419 | ADCY1 1.7392 | PGLYRP1 1.7352 | SLC9A3 1.7279 | CYP7B1 1.7230 | MTNR1A 1.7179 | IL6 1.7153 | ADORA1 1.7070 | CAPN5 1.7012 | STRA8 1.6857 | ICAM1 1.6718 | HLF 1.6717 | ANG 1.6605 | SRRD 1.6544 | PDGFRA 1.6489 | PER2 1.6329 | NOS3 1.6288 | INHBA 1.6220 | DRD2 1.5853 | TGFB2 1.5799 | NPY5R 1.5788 | BMP2 1.5776 | FBXL3 1.5581 | KDR 1.5543 | MMP19 1.5508 | F7 1.5496 | PRL 1.5478 | ADNP 1.5371 | HS3ST2 1.5337 | STAT5A 1.5114 | FANCG 1.4995 | CARTPT 1.4844 | DRD1 1.4777 | FBXL21 1.4775 | NMS 1.4461 | BHLHE41 1.4361 | OPN4 1.4347 | ADA 1.4333 | CRY2 1.4290 | HES7 1.4285 | NAGLU 1.4206 | SFRP4 1.4173 | CASP2 1.4160 | AXL 1.4159 | LEP 1.4143 | DDC 1.3973 | PTEN 1.3846 | KITLG 1.3781 | HEBP1 1.3776 | PROK2 1.3768 | CTNNA1 1.3657 | WNT5A 1.3655 | BMP15 1.3595 | BHLHE40 1.3567 | CCKBR 1.3511 | NOBOX 1.3482 | ENOX2 1.3193 | TPH2 1.3056 | HDAC3 1.2916 | SFRP1 1.2842 | UBE3A 1.2776 | TAF4 1.2681 | EIF2B5 1.2665 | ARNTL2 1.2465 | PGR 1.2410 | FSHB 1.2331 | CRY1 1.2203 | TNFRSF11A 1.2162 | FOXC1 1.2136 | PLEKHA1 1.2069 | LFNG 1.1848 | SFTPC 1.1843 | ANGPT1 1.1416 | MAT2A 1.1315 | INHBB 1.1310 | CLOCK 1.1255 | PMCH 1.1212 | ERMP1 1.1105 | BMP4 1.1081 | NR1D1 1.0727 | PER1 1.0699 | ADRBK1 1.0662 | ERBB3 1.0409 | PTGDS 1.0168 | TGFB3 1.0107 | STAT5B 1.0063 | GHRL 0.9974 | SFTPB 0.9886 | GPR149 0.9780 | FBXW11 0.9509 | CHRNB2 0.9425 | INHA 0.8631 | SOD1 0.8543 | CRH 0.8287 | SGPL1 0.8268 | BCL2L1 0.8053 | EREG 0.8038 | NKX2-1 0.7775 | PRKAA1 0.7726 | FZD4 0.7448 | PRF1 0.7335 | CSNK1D 0.7256 | CAT 0.6876 | SPO11 0.6482 | GNRH1 0.6442 | AHR 0.6079 | UTS2R 0.5807 | CENPI 0.4883 | NHLH2 0.4876 | CCNE1 0.4397 | ATOH7 0.3726 | EIF2B2 0.2862 | KGFLP2 0.1912 | KGFLP1 | estrogen receptor | |||||||||||||||||||
skeletal muscle organ development (boxplot) | 111 | 114 | 3.2130785923080802 | 6.566017494721299E-4 | 0.019106994062727697 | 0.005952380952380952 | GPHN 5.9364 | CAV1 3.7656 | DMD 3.6492 | PAX7 3.3979 | ERBB2 3.2295 | FOXP2 3.2196 | ADAM12 3.1898 | ASS1 3.0221 | MBNL1 2.8792 | METTL8 2.8193 | CAV2 2.8160 | CHAT 2.7603 | BASP1 2.7554 | RXRG 2.6680 | MUSK 2.5943 | COL4A1 2.5872 | KCNH1 2.5742 | CACNA1H 2.4410 | FOXP1 2.3270 | CDON 2.3231 | COL19A1 2.3157 | NOS1 2.3035 | MNX1 2.3035 | CACNB2 2.2123 | VGLL2 2.2100 | HOMER1 2.1943 | SKI 2.1799 | DNER 2.1720 | LRP4 2.1606 | FOXL2 2.1573 | APP 2.1303 | PDZRN3 2.0541 | MEF2C 2.0426 | CNTFR 2.0310 | WNT1 2.0180 | WNT10B | MYF5 1.9843 | MYF6 | NR2F2 1.9601 | MYL6 1.9522 | MYL6B 1.9522 | CTSB 1.9372 | TNC 1.9083 | GPX1 1.8947 | RHOA | MYL3 1.8709 | MEGF10 1.8707 | AFG3L2 1.8657 | HLX 1.8571 | RCAN1 1.8416 | BARX2 1.8319 | HOXD10 1.8126 | HOXD9 1.8126 | CHRND 1.7516 | MSC 1.7327 | CASQ1 1.6978 | DISP1 1.6927 | MYEF2 1.6778 | FGFRL1 1.6492 | IGF1 1.6014 | MYOG 1.5902 | LRRK2 1.5730 | CDK5 1.5715 | RYR1 1.5561 | FOXP3 1.5343 | KIAA1161 1.5218 | STRA6 1.5142 | NPHS1 1.4983 | LAMB2 1.4979 | EP300 1.4888 | WT1 1.4801 | SIN3B 1.4758 | F2R 1.4291 | PPP3CA 1.4235 | DNAJA3 1.4206 | SVIL 1.3995 | CACNA1S 1.3954 | CAPN2 1.3921 | CACNG2 1.3692 | IGFBP5 1.3648 | ALS2 1.3539 | CHRNA1 1.3109 | COL4A5 1.3070 | NF1 1.2913 | MYOD1 1.2690 | DVL1 1.2676 | SHH 1.2438 | DOK7 1.2147 | SRPK3 1.1942 | MYH9 1.1496 | MET 1.1441 | SORT1 1.1418 | DYRK1B 1.1007 | MYLK2 1.0997 | TAZ 1.0762 | TCF21 1.0756 | LEMD2 1.0653 | ERBB3 1.0409 | NRD1 1.0284 | DCN 1.0126 | ZNF238 1.0112 | CSRP3 1.0035 | PITX1 0.9816 | ACTA1 0.9736 | MAPK14 0.9700 | MEOX2 0.9481 | VAMP5 0.9005 | SIX1 0.8071 | SKIL 0.7578 | AVPR1A 0.6808 | SNTA1 0.5644 | SIX4 0.4859 | MYLPF 0.4455 | IGSF8 0.4340 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of transmembrane transporter activity (boxplot) | 97 | 97 | 3.2096998427049046 | 6.643682254829919E-4 | 0.019106994062727697 | 0.005917159763313609 | NRXN1 3.6097 | CACNB4 3.1376 | SHANK1 3.1256 | EFCAB4B 2.9151 | CACNA1C 2.8754 | OPRM1 2.8228 | NLGN1 2.7866 | CACNG3 2.6709 | YWHAH 2.6079 | PKD2L1 2.5895 | CXCL12 2.5696 | CAMK2D 2.5615 | TPCN2 2.5016 | STIM1 2.4544 | PLCG2 2.4205 | SESTD1 2.4004 | VDR 2.3912 | CAV3 2.3881 | AGT 2.2659 | CACNG4 2.2546 | NKX2-5 2.2385 | GLP1R 2.2306 | RELN 2.2249 | CACNB2 2.2123 | HOMER1 2.1943 | JPH3 2.1788 | BCL2 2.1766 | CACNA1D 2.1182 | CNIH2 2.1101 | RHOC 2.1005 | TWIST1 2.0979 | CACNA1E 2.0970 | PARK7 2.0872 | CCKAR 2.0865 | RIPK1 2.0686 | SHANK3 2.0446 | IL1RAPL1 2.0206 | CACNA2D1 1.9982 | PKD2 1.9879 | INS 1.9742 | GAS6 1.9676 | CACNG7 1.9540 | DRD3 1.9435 | JPH1 1.9422 | OPRD1 1.9420 | ASPH 1.9379 | CACNA1A 1.9305 | CNIH3 1.8983 | MAPK8IP2 1.8627 | CACNA1B 1.8481 | CACNG1 1.8336 | DRD4 1.8319 | ZP3 1.7758 | ITGAV 1.7509 | DLG4 1.7370 | CACNG6 1.6930 | CACNG5 1.6745 | NCS1 1.6216 | CACNA1I 1.6100 | ADRB1 1.6047 | NLGN3 1.5936 | DRD2 1.5853 | WNK2 1.5580 | RYR1 1.5561 | MYO5A 1.5529 | MINK1 1.4611 | STIM2 1.4476 | ACTN4 1.4437 | TRPC6 1.4311 | CACNA1S 1.3954 | FKBP1A 1.3770 | CACNG2 1.3692 | DAPK1 1.3354 | SCN1B 1.3219 | FKBP1B 1.3101 | ADORA2A 1.3027 | CACNG8 1.2699 | CACNB1 1.1775 | PLCG1 1.1759 | ADRA2A 1.1742 | JPH2 1.1317 | CALM2 1.1102 | CRHBP 1.0855 | SCN2B 1.0517 | ADRB2 1.0467 | WNK3 0.9692 | CACNA1F 0.9583 | CRH 0.8287 | TMEM66 0.8252 | RANGRF 0.7954 | CACNB3 0.7536 | AHCYL1 0.7381 | SLC9A3R1 0.7026 | NLGN2 0.6604 | GNAI2 0.5640 | EPO 0.4955 | JPH4 0.4863 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
fat cell differentiation (boxplot) | 76 | 76 | 3.206213109277114 | 6.724717119214185E-4 | 0.019214601078643572 | 0.0058823529411764705 | SIRT1 7.4176 | PRDM16 3.9381 | NIPBL 3.6793 | AACS 3.2912 | ARID5B 3.1718 | INSR 3.1624 | PID1 2.9916 | SOX8 2.8542 | METTL8 2.8193 | SNAI2 2.6919 | PLCB1 2.6151 | HMGA2 2.5708 | BBS9 2.5601 | PPARGC1A 2.4496 | ERAP1 2.4385 | CTBP2 2.3713 | NCOR2 2.2598 | ERO1L 2.2427 | RARRES2 2.2336 | RUNX1T1 2.2009 | NUDT7 2.1687 | TRIM32 2.1399 | BBS2 2.0939 | TCF7L2 2.0892 | LAMA4 2.0531 | LAMB3 2.0178 | CBY1 1.9948 | SOCS1 1.9877 | PTGS2 1.9806 | CCND1 1.9690 | CTBP1 1.9311 | GPX1 1.8947 | EGR2 1.8938 | ARL4A 1.8813 | ALMS1 1.8311 | AKT2 1.7769 | IL11 1.7083 | ATF2 1.7025 | PPARG 1.6692 | WNT5B 1.6264 | PSMB8 1.5897 | SLC2A4 1.5730 | BBS4 1.5605 | MKKS 1.5151 | MB 1.4850 | SDF4 1.4281 | MRAP 1.4047 | UCP1 1.3977 | CEBPA 1.3881 | SH2B2 1.3733 | PEX11A 1.3583 | ADIPOQ 1.3289 | FABP4 1.3200 | RETN 1.3060 | CEBPB 1.3007 | ARL6 1.2139 | INHBB 1.1310 | ID4 1.1089 | MED1 1.0961 | TTC8 1.0556 | KLF4 1.0448 | CLIP3 0.9895 | PRLH 0.9866 | SOCS7 0.9852 | RGS2 0.9397 | BNIP3 0.9338 | BBS7 0.9228 | STEAP4 0.8959 | ITGA6 0.8763 | NOC3L 0.8280 | LRG1 0.7868 | EIF2AK3 0.7800 | TFAP2B 0.7079 | FGF10 0.7055 | ADIG 0.4821 | ALDH6A1 0.4442 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of neurotransmitter levels (boxplot) | 101 | 103 | 3.2059996423424626 | 6.729707785766426E-4 | 0.019214601078643572 | 0.005847953216374269 | VAMP1 4.1635 | PCLO 4.0360 | PAH 4.0166 | PARK2 3.3357 | CPLX2 3.2544 | COLQ 2.7875 | NLGN1 2.7866 | PPFIA3 2.7612 | CHAT 2.7603 | SLC18A3 | STX1A 2.7012 | XBP1 2.6965 | SNPH 2.6851 | SYN2 2.6795 | SYT1 2.6792 | STXBP1 2.6367 | SPTBN2 2.5986 | COMT 2.5550 | CADPS 2.5522 | HRH3 2.5237 | NOS1 2.3035 | SLC6A4 2.2725 | SEPT5 2.2712 | SLC22A2 2.2511 | SLC1A3 2.1895 | GLS 2.1689 | SLC38A1 2.1315 | SLC18A2 2.0880 | PARK7 2.0872 | SYN3 2.0801 | WNT7A 2.0616 | BAIAP3 2.0183 | SNCA 1.9846 | TH 1.9742 | RIMS1 1.9395 | AP2B1 1.9360 | CACNA1A 1.9305 | SLC17A6 1.8970 | UNC13B 1.8915 | SYT4 1.8726 | P2RX7 1.8574 | SLC5A7 1.8496 | CACNA1B 1.8481 | DBH 1.8135 | PPT1 1.7921 | GRM4 1.7819 | SLC17A7 1.7655 | PRIMA1 1.7584 | SLC6A12 1.7455 | PIP5K1C 1.7353 | BRSK1 1.7013 | CPLX1 1.6807 | UNC13A 1.6800 | DOC2B 1.6682 | OTOF 1.6397 | SLC32A1 1.6305 | ALDH9A1 1.5934 | ALDH2 1.5891 | SLC38A2 1.5792 | CDK5 1.5715 | AGTPBP1 1.5597 | SLC6A11 1.5526 | DOC2A 1.5395 | GLUL 1.5159 | SYN1 1.4729 | SLC6A1 1.4647 | SNAP25 1.4539 | CLN8 1.4407 | RAB3A 1.4334 | NAALAD2 1.3997 | ABAT 1.3792 | LRTOMT 1.3465 | SNAPIN 1.3340 | CLN3 1.3063 | GCHFR 1.2795 | HSPA8 1.2788 | DNAJC5 1.2774 | DVL1 1.2676 | SYT2 1.2635 | GLS2 1.2509 | GABRA2 1.2072 | SLC6A3 1.1970 | PDE1B 1.1847 | SLC18A1 1.1645 | SLC22A3 1.1331 | SLC25A4 1.1125 | CPLX3 1.1056 | PLDN 1.1027 | GAD1 1.0859 | ALDH5A1 1.0747 | VAMP2 1.0699 | PSEN1 1.0274 | SLC6A13 1.0084 | ACHE 0.9394 | PEBP1 0.9211 | GAD2 0.8924 | KCNJ10 0.8338 | RAB14 0.7921 | STX4 0.6681 | SYNJ1 0.6101 | ATP1A2 0.4943 | MAOA 0.3928 | F5H0A2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
actomyosin structure organization (boxplot) | 45 | 46 | 3.196628324579282 | 6.95219814979442E-4 | 0.019634936508610135 | 0.005813953488372093 | RACGAP1 4.0312 | MYPN 3.2513 | TCAP 3.2295 | ANKRD1 2.9349 | PROX1 2.8868 | MYO18A 2.8163 | NEBL 2.7784 | TRPM7 2.7626 | CNN3 2.5363 | TTN 2.4386 | CDC42BPA 2.3339 | FOXP1 2.3270 | MYH11 2.2753 | NKX2-5 2.2385 | ACTB 2.1337 | MYOZ1 2.0827 | XIRP1 2.0504 | MEF2C 2.0426 | MYBPC3 1.9461 | ACTG1 1.9056 | MYH6 1.8142 | TMOD1 1.7664 | EPB41L4B 1.7269 | MYLK3 1.7219 | PDGFRA 1.6489 | CDC42BPB 1.6242 | LIMCH1 1.5992 | TPM1 1.5971 | CAPN3 1.5788 | KRT19 1.5729 | NEURL2 1.5580 | MYL2 1.5502 | MYH10 1.4980 | MEF2A 1.4880 | CNN2 1.2907 | PDGFRB 1.2307 | TNNT2 1.2243 | SRF 1.1778 | OBSL1 1.1569 | BMP10 1.1425 | ITGB1 1.1192 | ACTC1 1.1031 | ACTA1 0.9736 | EPB41L5 0.8760 | CNN1 0.5456 | HNTN1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
receptor clustering (boxplot) | 20 | 20 | 3.1964255814410145 | 6.95708571439746E-4 | 0.019634936508610135 | 0.005780346820809248 | NRXN1 3.6097 | MAGI2 3.4637 | GRIK2 3.2889 | DLG2 3.2580 | NLGN1 2.7866 | MUSK 2.5943 | GRIN2B 2.2951 | LRP4 2.1606 | SHANK3 2.0446 | CACNA1A 1.9305 | SMO 1.8103 | DLG4 1.7370 | CDK5 1.5715 | AGRN 1.5051 | DNAJA3 1.4206 | PICK1 1.3992 | DVL1 1.2676 | DOK7 1.2147 | SYNGAP1 1.1743 | FLNA 0.9266 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
phospholipid transport (boxplot) | 30 | 32 | 3.194901967274174 | 6.993917252960946E-4 | 0.019634936508610135 | 0.005747126436781609 | ABCA1 5.6064 | ATP9A 3.8389 | ATP11A 3.7283 | APOA1 3.0248 | APOC3 | PITPNA 2.6811 | SCARB1 2.6205 | APOA4 2.5911 | ATP10D 2.2069 | ATP10A 2.1905 | ABCG1 2.0741 | LDLR 1.9157 | ABCA4 1.9148 | P2RX7 1.8574 | PLA2G10 1.7764 | ATP9B 1.7613 | NPC2 1.7277 | CETP 1.6214 | ATP10B 1.5905 | KCNN4 1.5095 | ABCG8 1.4958 | APOE 1.4398 | ATP8B1 1.3825 | APOC1 1.3441 | APOC2 | ATP11B 1.2915 | ABCA7 1.2907 | ATP8A1 1.2627 | PCTP 1.1922 | ATP8B3 0.9821 | APOA2 0.8951 | ATP11C 0.5439 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
telencephalon cell migration (boxplot) | 36 | 36 | 3.1933882417355073 | 7.030687723774687E-4 | 0.019634936508610135 | 0.005714285714285714 | ARX 6.2843 | SLIT1 3.2641 | TNR 3.0413 | DAB1 2.9720 | NR2E1 2.8955 | SLIT2 2.8500 | EGFR 2.8090 | CXCL12 2.5696 | SLIT3 2.4489 | GLI3 2.3270 | RTN4 2.3237 | OGDH 2.3215 | CNTN2 2.2820 | RELN 2.2249 | ROBO1 2.1673 | LRP6 2.0780 | LRP8 1.6538 | DRD2 1.5853 | LRRK2 1.5730 | FGFR1 1.5730 | CDK5 1.5715 | NDEL1 1.5703 | FOXB1 1.5142 | DRD1 1.4777 | POU3F2 1.4263 | PEX5 1.3972 | CX3CR1 1.2922 | POU3F3 1.1996 | SRF 1.1778 | LHX6 1.0642 | PSEN1 1.0274 | CDK5R1 0.9094 | PAFAH1B1 0.8148 | NKX2-1 0.7775 | PEX13 0.7502 | DIXDC1 0.6947 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cyclic nucleotide metabolic process (boxplot) | 96 | 97 | 3.1865311754262944 | 7.19949843626333E-4 | 0.01987386969467945 | 0.005681818181818182 | ABCA1 5.6064 | ADORA3 4.1949 | PDE2A 3.7330 | GHRH 3.4507 | GRM8 3.2143 | GNAL 3.0690 | GNG7 2.8840 | GRM7 2.8268 | OPRM1 2.8228 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | GUCY1A3 2.4867 | HTR1B 2.3684 | MC1R 2.3626 | EDN1 2.3459 | ADORA2B 2.3294 | GABBR2 2.2343 | GLP1R 2.2306 | PDZD3 2.1882 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | PKD2 1.9879 | GABBR1 1.9622 | DRD3 1.9435 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | DRD4 1.8319 | ADCYAP1 1.8068 | FZD2 1.8049 | CAP1 1.7921 | EDNRB 1.7889 | LHCGR 1.7607 | ADM 1.7485 | MTNR1A 1.7179 | PALM 1.7163 | RAF1 1.7090 | GHRHR 1.6541 | NOS3 1.6288 | ADRB1 1.6047 | CBS 1.6003 | DRD2 1.5853 | P2RY11 1.5469 | AIPL1 1.5397 | ADNP 1.5371 | NPPC 1.5320 | INSL3 1.5247 | APLP1 1.4983 | DRD1 1.4777 | RAMP1 1.4694 | GNAI3 1.4435 | NPR3 1.4425 | APOE 1.4398 | OXER1 1.4362 | ADCY7 1.4224 | MRAP 1.4047 | LTB4R2 1.3819 | TIMP2 1.3794 | WNT5A 1.3655 | CRHR1 1.3545 | MC5R 1.3486 | NPR1 1.3340 | GRM3 1.3280 | GALR1 1.3255 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | ADRA2A 1.1742 | CCR2 1.1711 | CALCR 1.1467 | MC4R 1.1026 | GRM2 1.0960 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | GALR3 0.8839 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | GNAI2 0.5640 | HCTR-6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of synapse organization (boxplot) | 42 | 43 | 3.1864495251456884 | 7.201530864884287E-4 | 0.01987386969467945 | 0.005649717514124294 | NRXN1 3.6097 | SLIT1 3.2641 | ROBO2 3.0085 | CAMK1 2.9695 | NLGN1 2.7866 | ASIC2 2.7474 | EPHB2 2.7088 | EPHB1 2.6334 | PDLIM5 2.6326 | MUSK 2.5943 | THBS2 2.4552 | OXTR 2.3881 | CTNNA2 2.3669 | CAMK2B 2.2519 | RELN 2.2249 | CDC20 2.0817 | WNT7A 2.0616 | SHANK3 2.0446 | OXT 1.9195 | SYNDIG1 1.8308 | NEUROD2 1.8013 | ANAPC2 1.7859 | UBE2V2 1.7203 | GHSR 1.7166 | NLGN3 1.5936 | FRMPD4 1.5631 | PVRL1 1.5566 | ADNP 1.5371 | AGRN 1.5051 | LRRC4B 1.4908 | SNAP25 1.4539 | KLK8 1.4015 | PTK2 1.3822 | WNT5A 1.3655 | ARHGEF15 1.2884 | NCAN 1.2768 | BDNF 1.2240 | GHRL 0.9974 | CHRNB2 0.9425 | DMPK 0.8803 | NLGN2 0.6604 | EPHB3 0.6149 | CSPG3 variant protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cAMP biosynthetic process (boxplot) | 82 | 83 | 3.185639215705248 | 7.221729673939636E-4 | 0.01987386969467945 | 0.0056179775280898875 | ABCA1 5.6064 | ADORA3 4.1949 | PDE2A 3.7330 | GHRH 3.4507 | GRM8 3.2143 | GNAL 3.0690 | GNG7 2.8840 | GRM7 2.8268 | OPRM1 2.8228 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | HTR1B 2.3684 | MC1R 2.3626 | EDN1 2.3459 | ADORA2B 2.3294 | GABBR2 2.2343 | GLP1R 2.2306 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | GABBR1 1.9622 | DRD3 1.9435 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | DRD4 1.8319 | ADCYAP1 1.8068 | CAP1 1.7921 | EDNRB 1.7889 | LHCGR 1.7607 | ADM 1.7485 | PALM 1.7163 | RAF1 1.7090 | GHRHR 1.6541 | ADRB1 1.6047 | DRD2 1.5853 | P2RY11 1.5469 | INSL3 1.5247 | APLP1 1.4983 | DRD1 1.4777 | RAMP1 1.4694 | GNAI3 1.4435 | NPR3 1.4425 | OXER1 1.4362 | ADCY7 1.4224 | MRAP 1.4047 | LTB4R2 1.3819 | CRHR1 1.3545 | MC5R 1.3486 | GRM3 1.3280 | GALR1 1.3255 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | ADRA2A 1.1742 | CCR2 1.1711 | CALCR 1.1467 | MC4R 1.1026 | GRM2 1.0960 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | GALR3 0.8839 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | GNAI2 0.5640 | HCTR-6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
actin filament binding (boxplot) | 71 | 71 | 3.185356566794369 | 7.22878761738377E-4 | 0.01987386969467945 | 0.00558659217877095 | CORO2A 3.6618 | MYO16 3.5430 | LCP1 3.4460 | MACF1 3.3194 | ARPC4 2.9695 | PKNOX2 2.8472 | EGFR 2.8090 | NEBL 2.7784 | ADD1 2.5292 | MYO1E 2.5057 | SPTBN5 2.4987 | TTN 2.4386 | LASP1 2.3015 | SLC6A4 2.2725 | PLS1 2.2542 | SHROOM2 2.1572 | GAS7 2.0984 | LIMA1 2.0815 | AIF1 2.0797 | FGD4 2.0673 | CORO7 2.0484 | ACTN1 2.0386 | TRPV4 2.0262 | CYFIP1 1.9503 | TULP1 1.9365 | GAS2L2 1.9360 | MYO6 1.9297 | CORO1B 1.9131 | FSCN2 1.9056 | ANTXR1 1.9030 | CORO2B 1.8780 | TNNC1 1.8440 | MYO10 1.7867 | ADD2 1.7611 | ABL2 1.7537 | VIL1 1.7405 | VPS16 1.7396 | NEXN 1.7265 | ACTN2 1.7215 | MYO7A 1.7012 | FSCN3 1.6957 | FSCN1 1.6954 | UXT 1.6910 | SCIN 1.6737 | MARCKS 1.6411 | MYO5C 1.6330 | RCSD1 1.5736 | MYO5A 1.5529 | MYH10 1.4980 | ACTN4 1.4437 | ESPN 1.4330 | SVIL 1.3995 | LRPPRC 1.3888 | CTNNA1 1.3657 | AJUBA 1.3552 | MAP1S 1.3325 | SPTA1 1.2678 | MYL4 1.2440 | CORO1C 1.2439 | KLHL17 1.1909 | MYH9 1.1496 | EZR 1.1330 | SPTB 1.0618 | AIF1L 1.0549 | ERMN 1.0218 | CORO1A 0.9727 | SHROOM1 0.9655 | SHROOM4 0.9493 | FLNA 0.9266 | DBNL 0.8579 | CORO6 0.7049 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cAMP metabolic process (boxplot) | 84 | 85 | 3.1851286285871123 | 7.234484026221732E-4 | 0.01987386969467945 | 0.005555555555555556 | ABCA1 5.6064 | ADORA3 4.1949 | PDE2A 3.7330 | GHRH 3.4507 | GRM8 3.2143 | GNAL 3.0690 | GNG7 2.8840 | GRM7 2.8268 | OPRM1 2.8228 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | HTR1B 2.3684 | MC1R 2.3626 | EDN1 2.3459 | ADORA2B 2.3294 | GABBR2 2.2343 | GLP1R 2.2306 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | PKD2 1.9879 | GABBR1 1.9622 | DRD3 1.9435 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | DRD4 1.8319 | ADCYAP1 1.8068 | CAP1 1.7921 | EDNRB 1.7889 | LHCGR 1.7607 | ADM 1.7485 | PALM 1.7163 | RAF1 1.7090 | GHRHR 1.6541 | ADRB1 1.6047 | DRD2 1.5853 | P2RY11 1.5469 | INSL3 1.5247 | APLP1 1.4983 | DRD1 1.4777 | RAMP1 1.4694 | GNAI3 1.4435 | NPR3 1.4425 | OXER1 1.4362 | ADCY7 1.4224 | MRAP 1.4047 | LTB4R2 1.3819 | TIMP2 1.3794 | CRHR1 1.3545 | MC5R 1.3486 | GRM3 1.3280 | GALR1 1.3255 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | ADRA2A 1.1742 | CCR2 1.1711 | CALCR 1.1467 | MC4R 1.1026 | GRM2 1.0960 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | GALR3 0.8839 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | GNAI2 0.5640 | HCTR-6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lipid localization (boxplot) | 163 | 168 | 3.1772475017700064 | 7.434004644113479E-4 | 0.019957443236889263 | 0.0055248618784530384 | ABCA1 5.6064 | ATP9A 3.8389 | CAV1 3.7656 | ATP11A 3.7283 | PRKAG2 3.7137 | SOAT1 3.1809 | OSBP2 3.1687 | TNF 3.0639 | HEXA 3.0328 | APOA1 3.0248 | APOC3 | SPNS1 2.8728 | APOL2 2.7531 | PITPNA 2.6811 | SCARB1 2.6205 | APOA4 2.5911 | APOA5 2.5911 | OSBPL1A 2.5615 | OSBPL2 2.5237 | SORL1 2.4985 | SLC27A6 2.4755 | OSBPL6 2.4610 | NPC1L1 2.4288 | ACACB 2.4178 | BDKRB2 2.4033 | OSBP 2.3947 | OSBPL8 2.3928 | PLA2G5 2.3447 | HEXB 2.3391 | PLA2G4A 2.3298 | OSBPL7 2.3205 | APOL1 2.2821 | RBP4 2.2565 | PSAP 2.2453 | ABCA12 2.2331 | ACSL1 2.2283 | COL4A3BP 2.2085 | ATP10D 2.2069 | ATP10A 2.1905 | ABCG4 2.1882 | SLC27A5 2.1872 | NRIP1 2.1803 | LCAT 2.1598 | APOM 2.1586 | SLCO2A1 2.1406 | OSBPL3 2.1038 | LRP6 2.0780 | ABCG1 2.0741 | ACSL5 2.0627 | PLA2G4F 2.0368 | GPIHBP1 2.0087 | SLC27A4 1.9556 | APOL4 1.9491 | DRD3 1.9435 | LDLR 1.9157 | ABCA4 1.9148 | APOLD1 1.8825 | IL1B 1.8813 | CPT1B 1.8780 | PRKAA2 1.8703 | P2RX7 1.8574 | DRD4 1.8319 | ANXA1 1.8032 | OSBPL10 1.8013 | PLA2G10 1.7764 | ATP9B 1.7613 | SPNS3 1.7608 | LHCGR 1.7607 | CFHR4 1.7519 | PLTP 1.7340 | NPC2 1.7277 | KISS1R 1.7173 | GLTP 1.7122 | DGAT1 1.7111 | PPARG 1.6692 | CIDEA 1.6633 | STARD5 1.6612 | APOD 1.6583 | OSBPL11 1.6550 | SLC27A2 1.6261 | INHBA 1.6220 | CETP 1.6214 | ACVR1C 1.6115 | HNF1A 1.6105 | VLDLR 1.6091 | STARD4 1.6060 | LIPC 1.6053 | ATP10B 1.5905 | DRD2 1.5853 | LRP10 1.5699 | PPARD 1.5657 | GULP1 1.5464 | APOL6 1.5397 | OSBPL5 1.5351 | CPT2 1.5335 | APOL5 1.5325 | STAT5A 1.5114 | KCNN4 1.5095 | SPNS2 1.4984 | ABCG5 1.4958 | ABCG8 1.4958 | CD36 1.4667 | HDLBP 1.4658 | CLN8 1.4407 | APOE 1.4398 | LDLRAP1 1.4279 | DGAT2 1.4198 | ANGPTL3 1.4147 | LBP 1.3981 | SIGMAR1 1.3875 | ATP8B1 1.3825 | CFTR 1.3770 | PLIN2 1.3717 | SCP2 1.3496 | APOC1 1.3441 | APOC2 | APOC4 | LPA 1.3392 | SLC27A1 1.3359 | LIPG 1.3223 | APOBR 1.3063 | ATP11B 1.2915 | ABCA7 1.2907 | CHKA 1.2791 | GOT2 1.2785 | MSR1 1.2705 | ATP8A1 1.2627 | CLU 1.2550 | APOB 1.2451 | APOH 1.2376 | MTTP 1.2284 | ABCA5 1.2038 | PCTP 1.1922 | ENPP1 1.1901 | GM2A 1.1879 | CPT1A 1.1834 | VPS4B 1.1509 | CEL 1.1461 | B4GALNT1 1.1174 | PRKAB2 1.0760 | PNLIP 1.0731 | NMUR2 1.0684 | AKR1C1 1.0665 | PPARA 1.0266 | STAT5B 1.0063 | ATP8B3 0.9821 | SERPINA5 0.9719 | NPC1 0.9459 | ARV1 0.9451 | STARD6 0.9323 | APOA2 0.8951 | CROT 0.8342 | SOAT2 0.7990 | APOO 0.7820 | APOL3 0.7791 | ACE 0.7753 | SFTPA1 0.7503 | FZD4 0.7448 | APOF 0.7358 | SLC25A20 0.7171 | SLC25A17 0.6778 | STX12 0.6580 | OSBPL9 0.6068 | ATP11C 0.5439 | ABCD1 0.5027 | PLA2G1B 0.4953 | ADFP | FFR | |||||||||||||||||||||||||||||||||||||||
cAMP metabolic process (boxplot) | 32 | 32 | 3.1761930792472937 | 7.461079882649102E-4 | 0.019957443236889263 | 0.005494505494505495 | PDE2A 3.7330 | ADCY10 3.5194 | PDE10A 3.5081 | PDE4B 3.1574 | PDE8A 3.0407 | PDE11A 2.9328 | PDE4D 2.8834 | PDE7B 2.6103 | PTHLH 2.5819 | ADCY2 2.5386 | PDE3A 2.3821 | PDE1C 2.1963 | ADCY3 2.1650 | CALCRL 1.8557 | ADM 1.7485 | ADCY9 1.7405 | ADCY1 1.7392 | ADCY8 1.7139 | PDE3B 1.7081 | ADCY4 1.4548 | PDE4C 1.4334 | ADCY7 1.4224 | PDE8B 1.3712 | ADORA2A 1.3027 | PDE7A 1.2485 | PTH 1.2270 | GNAS 1.1857 | PDE1B 1.1847 | RAMP2 0.9523 | UCN2 0.7722 | ADCY6 0.7536 | PDE4A 0.7502 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
binding, bridging (boxplot) | 140 | 141 | 3.170137008457449 | 7.618353756513319E-4 | 0.020230041551263084 | 0.00546448087431694 | CRK 4.9972 | COL11A2 4.6854 | BICD1 4.2108 | GRB2 3.5564 | FKBP4 3.2506 | EVPL 2.9838 | ARPC4 2.9695 | ARHGAP10 2.9174 | LAT 2.8728 | BAIAP2 2.7979 | CHN2 2.7414 | COL6A2 2.7393 | STX1A 2.7012 | RBM14 2.6896 | FRS2 2.5419 | ARHGAP26 2.5226 | CRADD 2.4878 | BIN3 2.4249 | SKAP1 2.4173 | SHB 2.4114 | CLNK 2.3813 | MAPK8IP1 2.3164 | COL19A1 2.3157 | CRKL 2.3083 | LASP1 2.3015 | SH2D3C 2.2820 | FCRL2 2.2566 | CUX1 2.2383 | GAB2 2.2298 | MPP7 2.2168 | BLNK 2.2008 | HOMER1 2.1943 | COL14A1 2.1863 | ARHGAP6 2.1854 | CD28 2.1569 | ITSN2 2.1500 | GAB1 2.1327 | MEN1 2.0976 | SH3RF1 2.0775 | GRB10 2.0523 | SH2D2A 2.0466 | SH3BP2 2.0378 | SH2D1B 2.0268 | PSMC6 1.9935 | GAS6 1.9676 | HSH2D 1.9590 | ASAP1 1.9430 | GAS2L2 1.9360 | IRS1 1.9115 | PAG1 1.9087 | FSCN2 1.9056 | TRADD 1.8740 | PRKAA2 1.8703 | MAPK8IP2 1.8627 | SLA 1.8438 | VAV3 1.8406 | SORBS2 1.8388 | SH3BGR 1.8241 | ANXA1 1.8032 | ACAP3 1.8009 | GATAD2A 1.7930 | ANK1 1.7885 | MAPK8IP3 1.7605 | ABI2 1.7385 | GRAP2 1.7178 | COL8A2 1.7125 | ADAP2 1.6995 | FLRT1 1.6980 | FSCN3 1.6957 | FSCN1 1.6954 | BAIAP2L1 1.6951 | SH3GLB2 1.6870 | SKAP2 1.6689 | SORBS1 1.6523 | GAS2L1 1.6509 | TIRAP 1.6414 | STAM 1.6170 | DOK2 1.6163 | STAP1 1.6094 | SRC 1.5906 | PPP4R2 1.5834 | PDCD6 1.5772 | CNKSR1 1.5044 | LOR 1.5031 | DAB2IP 1.4910 | EPS8 1.4871 | CHN1 1.4789 | CBX5 1.4600 | ARHGAP1 1.4596 | NCK2 1.4470 | GRB14 1.4400 | NUFIP1 1.4362 | COL11A1 1.4339 | LDLRAP1 1.4279 | COL1A2 1.4123 | BAIAP2L2 1.3992 | TOB1 1.3959 | GRAP 1.3954 | SH2B2 1.3733 | SLA2 1.3387 | MTSS1 1.3065 | SHC1 1.2933 | RAD50 1.2733 | SH3GLB1 1.2730 | CNTNAP1 1.2662 | FGB 1.2648 | TNNT2 1.2243 | ARHGAP42 1.2122 | GRB7 1.1828 | GOLGA5 1.1812 | FGA 1.1804 | OBSL1 1.1569 | MMS19 1.1470 | BCL3 1.1329 | MTSS1L 1.1236 | SH2D3A 1.1155 | FLRT2 1.0677 | TP53BP2 1.0534 | STUB1 1.0527 | SH2D1A 1.0331 | DSP 1.0262 | IRS4 1.0252 | SH3BGRL 1.0131 | FLRT3 0.8901 | DUSP19 0.8851 | SDCBP 0.8733 | OPHN1 0.8605 | FGG 0.8458 | TRAT1 0.8232 | SOCS2 0.8180 | SPRR1A 0.8078 | ARHGAP4 0.7810 | NCK1 0.7460 | HSPA5 0.6930 | IVL 0.6857 | ST13 0.6778 | SPRR1B 0.6655 | RUSC1 0.5709 | KHDRBS1 0.5046 | CSTA 0.4033 | HNTN1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
membrane depolarization (boxplot) | 59 | 59 | 3.169207113072568 | 7.642771461657816E-4 | 0.020230041551263084 | 0.005434782608695652 | SCN3B 4.2468 | CAV1 3.7656 | NRXN1 3.6097 | GRIK2 3.2889 | CACNB4 3.1376 | SHANK1 3.1256 | CACNA1G 3.0242 | GRID2 3.0003 | NLGN1 2.7866 | EDN1 2.3459 | NLGN4X 2.3043 | GRIN2B 2.2951 | SCN5A 2.2668 | CACNG4 2.2546 | RELN 2.2249 | AIFM3 2.2178 | CACNA1E 2.0970 | GRIN2A 2.0931 | PARK7 2.0872 | ATXN1 2.0856 | SHANK3 2.0446 | SNCA 1.9846 | GRIN2C 1.9757 | CACNA1A 1.9305 | JUN 1.8868 | MAPK8IP2 1.8627 | P2RX7 1.8574 | CACNA1B 1.8481 | KCNE1 1.8416 | GRIK1 1.8243 | PRKCZ 1.7929 | SLC17A7 1.7655 | DLG4 1.7370 | ADORA1 1.7070 | BEST2 1.6024 | NLGN3 1.5936 | CDK5 1.5715 | P2RX4 1.5095 | SMAD7 1.4674 | PPP3CA 1.4235 | PTEN 1.3846 | CACNG2 1.3692 | ADIPOQ 1.3289 | SCN1B 1.3219 | SLC29A1 1.3140 | ADORA2A 1.3027 | GRIN1 1.2637 | CHRNA4 1.2001 | CHRNA3 1.1921 | MTMR2 1.0519 | SCN2B 1.0517 | ADRB2 1.0467 | GHRL 0.9974 | CHRNB2 0.9425 | DMPK 0.8803 | CACNB3 0.7536 | NLGN2 0.6604 | HCRT 0.5645 | CHRNA6 0.3958 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cellular response to retinoic acid (boxplot) | 47 | 48 | 3.1635599253106794 | 7.792613133705828E-4 | 0.020470272995315418 | 0.005405405405405406 | ABCA1 5.6064 | NTRK3 4.8124 | RXRB 4.6854 | EPHA3 2.7107 | FZD10 2.6723 | WNT9A 2.5288 | SOX9 2.4914 | IRF1 2.4722 | SLC6A4 2.2725 | WNT11 2.1927 | FZD7 2.1227 | ALDH1A2 2.0957 | WNT3 2.0876 | LTK 2.0786 | TWF2 2.0553 | WNT9B 2.0446 | WNT10B 2.0180 | RET 1.9319 | TBX1 1.8661 | WNT7B 1.8583 | PAX2 1.8357 | KRT13 1.8072 | ADNP2 1.7998 | CYP26B1 1.7548 | ABL2 1.7537 | AQP1 1.7153 | STRA8 1.6857 | PTK7 1.6724 | WNT3A 1.6407 | WNT5B 1.6264 | LYN 1.5986 | WNT2 1.5764 | COL1A1 1.4835 | LEP 1.4143 | MLL5 1.3929 | WNT5A 1.3655 | CYP26A1 1.1740 | PTK6 1.1515 | PTK2B 1.1280 | WNT6 1.0632 | RARA 1.0131 | OSR1 0.9759 | WNT8B 0.9546 | ZNF35 0.7454 | FZD4 0.7448 | OGT 0.6705 | SNW1 0.5348 | RALDH2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
calcium ion transport (boxplot) | 134 | 135 | 3.1578659176849264 | 7.946431924363839E-4 | 0.02076270929542338 | 0.005376344086021506 | CAV1 3.7656 | PDE2A 3.7330 | ANXA6 3.7088 | FYN 3.7055 | PSEN2 3.3139 | RYR2 3.1737 | GRIN3A 3.1467 | CUL5 3.0470 | CDH23 2.9737 | CHERP 2.9269 | EFCAB4B 2.9151 | CACNA1C 2.8754 | ATP2B2 2.8342 | BSPRY 2.7881 | SLC8A1 2.7718 | PRKCE 2.7354 | BBC3 2.6870 | CACNG3 2.6709 | RYR3 2.5711 | CAMK2D 2.5615 | TPCN2 2.5016 | STIM1 2.4544 | PLCG2 2.4205 | VDR 2.3912 | CCR7 2.3166 | CAMK2B 2.2519 | CSN2 2.2365 | GLP1R 2.2306 | CACNB2 2.2123 | TRPV1 2.1980 | JPH3 2.1788 | ADRA1A 2.1619 | ITPR2 2.1594 | CAMK2A 2.1496 | CACNA1D 2.1182 | SLC30A1 2.0329 | TRPV4 2.0262 | CACNA2D1 1.9982 | PKD2 1.9879 | SLC24A4 1.9794 | RAMP3 1.9727 | CACNG7 1.9540 | P2RX1 1.9501 | JPH1 1.9422 | CLCA1 1.9393 | ASPH 1.9379 | HTR2B 1.9303 | SLC8A3 1.9072 | SLN 1.8957 | CACHD1 1.8823 | CYSLTR1 1.8716 | P2RX7 1.8574 | ASIC1 1.8572 | CALCRL 1.8557 | TRPM1 1.8355 | CCL5 1.8122 | GJA4 1.7960 | EFCAB4A 1.7743 | SLC24A1 1.7667 | ITPR3 1.7657 | CACNG6 1.6930 | ATP2A2 1.6834 | SLC24A5 1.6778 | IBTK 1.6756 | CHRNA7 1.6719 | SLC24A6 1.6711 | PANX1 1.6650 | TRPM2 1.6363 | REST 1.6316 | TRPC4 1.6274 | CACNA1I 1.6100 | TRPC5 1.6072 | MCU 1.6010 | DRD2 1.5853 | HTR2A 1.5850 | NPY 1.5849 | RYR1 1.5561 | ATP2C1 1.5260 | KCNN4 1.5095 | P2RX4 1.5095 | SLC8A2 1.4933 | TRPV5 1.4897 | TPT1 1.4838 | RAMP1 1.4694 | STIM2 1.4476 | ITPR1 1.4342 | MCOLN1 1.4312 | F2R 1.4291 | PPP3CA 1.4235 | MS4A2 1.4184 | PTPRC 1.4182 | SLC3A2 1.4035 | CACNA1S 1.3954 | ATP2A1 1.3612 | TRPC3 1.3214 | LCK 1.3129 | FKBP1B 1.3101 | CYP27B1 1.2985 | CACNG8 1.2699 | GRIN1 1.2637 | CCL19 1.2605 | CCL21 | BHLHA15 1.2296 | CCR1 1.2203 | CASR 1.2002 | CHRNA4 1.2001 | XCL1 1.1948 | PLCG1 1.1759 | CCR5 1.1711 | TRPV2 1.1404 | JPH2 1.1317 | FGF2 1.1278 | NMUR2 1.0684 | GRIN3B 1.0627 | PSEN1 1.0274 | ATP2A3 0.9855 | CORO1A 0.9727 | TRPC1 0.9629 | CTGF 0.9616 | RAMP2 0.9523 | HTR2C 0.9475 | CHRNB2 0.9425 | CCL3 0.9396 | PLN 0.9193 | MICU1 0.8856 | PKD1 0.8841 | SRI 0.8747 | TMEM66 0.8252 | CCL8 0.7797 | NMUR1 0.7701 | CACNB3 0.7536 | TRPV6 0.5852 | XCR1 0.5364 | PLCZ1 0.4867 | JPH4 0.4863 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
memory (boxplot) | 64 | 64 | 3.147074064719658 | 8.245659134009653E-4 | 0.02142994177062296 | 0.0053475935828877 | PSEN2 3.3139 | NTF4 3.2839 | SHANK1 3.1256 | RASGRF1 2.9288 | GRM7 2.8268 | CHAT 2.7603 | PLCB1 2.6151 | NETO1 2.5980 | MUSK 2.5943 | CAMK4 2.5094 | PLK2 2.4876 | PPP3CB 2.4174 | SERPINF1 2.4022 | OXTR 2.3881 | GRIN2B 2.2951 | SLC6A4 2.2725 | SGK1 2.2618 | GLP1R 2.2306 | JPH3 2.1788 | GRIN2A 2.0931 | SHANK3 2.0446 | NGF 2.0438 | ATAD1 2.0096 | PTGS2 1.9806 | RGS14 1.9785 | TH 1.9742 | ITGA8 1.9537 | SLC24A2 1.9291 | OXT 1.9195 | IL1B 1.8813 | DRD4 1.8319 | DBH 1.8135 | SLC17A7 1.7655 | ADCY1 1.7392 | CYP7B1 1.7230 | ADCY8 1.7139 | CHRNA7 1.6719 | CHST10 1.6519 | VLDLR 1.6091 | TAC1 1.6069 | CNR1 1.6061 | ADRB1 1.6047 | DRD2 1.5853 | HTR2A 1.5850 | ADNP 1.5371 | DRD1 1.4777 | SNAP25 1.4539 | KLK8 1.4015 | CRHR1 1.3545 | TACR1 1.3533 | ITGA3 1.3270 | MDK 1.2489 | RPS6KB1 1.2260 | ATP1A3 1.1872 | SRF 1.1778 | GRIA1 1.1475 | PDE5A 1.1185 | PSEN1 1.0274 | PJA2 1.0179 | S100B 0.9943 | CHRNB2 0.9425 | ITGA5 0.8380 | CRH 0.8287 | NTAN1 0.4376 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of actin filament bundle assembly (boxplot) | 42 | 43 | 3.1470383298168687 | 8.24666695754539E-4 | 0.02142994177062296 | 0.005319148936170213 | ARHGEF10 3.8915 | ARAP1 3.7330 | INPP5K 3.5378 | PARK2 3.3357 | NF2 3.2554 | SYNPO 2.9309 | EPHA1 2.5465 | TACSTD2 2.4154 | SERPINF2 2.4022 | SORBS3 2.3613 | FHOD1 2.2999 | DLC1 2.2963 | AMOT 2.2199 | WNT11 2.1927 | ARHGAP6 2.1854 | SMAD3 2.1433 | ROCK2 2.0790 | MAP3K1 1.9924 | RHOA 1.8947 | MTOR 1.7516 | VIL1 1.7405 | KISS1R 1.7173 | TAC1 1.6069 | TPM1 1.5971 | PTGER4 1.5596 | PRKCQ 1.5129 | ARHGEF10L 1.4113 | BAG4 1.3675 | TACR1 1.3533 | TSC1 1.3322 | SDC4 1.2900 | ARHGEF15 1.2884 | SFRP1 1.2842 | PLEK 1.2748 | PPM1F 1.1863 | LIMK1 1.1825 | ROCK1 1.1687 | PAK1 1.1424 | S1PR1 1.0347 | CTGF 0.9616 | GPR65 0.8893 | PPM1E 0.7885 | FRAP1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
polypeptide N-acetylgalactosaminyltransferase activity (boxplot) | 20 | 20 | 3.1466557624559885 | 8.257463524323772E-4 | 0.02142994177062296 | 0.005291005291005291 | GALNT13 4.0956 | WBSCR17 3.3043 | GALNTL2 2.8218 | GALNTL1 2.7475 | GALNTL6 2.6522 | GALNT9 2.4894 | GALNT2 2.4501 | GALNT8 2.4089 | GALNTL4 2.3850 | GALNT6 2.1597 | GALNT3 2.1595 | GALNT14 2.0999 | GALNT5 1.5463 | GALNT1 1.3774 | GALNT7 1.3252 | GALNT10 1.1544 | GALNT4 1.1174 | C1GALT1C1 1.0766 | GALNT12 1.0326 | GALNT11 0.8956 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of JNK cascade (boxplot) | 117 | 120 | 3.1410433193596474 | 8.417356492880224E-4 | 0.02153256744723182 | 0.005263157894736842 | MECOM 4.3913 | CD27 4.1635 | FGF19 4.0340 | TAOK2 3.3686 | ERCC6 3.3262 | GRIK2 3.2889 | MAP3K5 3.1884 | HIPK2 3.1565 | MAP3K7 3.1402 | MAP2K7 3.0946 | TNF 3.0639 | RAP2A 3.0635 | MAP4K5 2.9285 | TLR6 2.8628 | FZD10 2.6723 | HRAS 2.6539 | EPHB1 2.6334 | PLCB1 2.6151 | TLR9 2.5867 | IGF1R 2.4090 | SERPINF2 2.4022 | TAOK1 2.3462 | EDN1 2.3459 | CCR7 2.3166 | MAPK8IP1 2.3164 | NCOR1 2.1739 | TP73 2.1456 | GAB1 2.1327 | FZD7 2.1227 | SYK 2.1149 | AKT1 2.1144 | MEN1 2.0976 | SH3RF1 2.0775 | RIPK1 2.0686 | FGD4 2.0673 | WNT7A 2.0616 | AXIN1 1.9756 | BIRC7 1.9322 | IL1B 1.8813 | MAPK8IP2 1.8627 | WNT7B 1.8583 | PPEF2 1.8557 | DUSP22 1.8282 | DAXX 1.8243 | ZMYND11 1.8152 | MYD88 1.7773 | AKT2 1.7769 | MAPK8IP3 1.7605 | COPS5 1.7528 | GSTP1 1.7474 | HIPK3 1.7433 | TNFSF11 1.7065 | AMBP 1.6978 | MAP3K4 1.6850 | EPHA4 1.6721 | MAP3K10 1.6660 | MAP4K2 1.6645 | MAP3K9 1.6641 | MDFI 1.6601 | TIRAP 1.6414 | F2RL1 1.6183 | MAP3K2 1.6004 | CBS 1.6003 | MAP3K11 1.5775 | GPS2 1.5730 | SPAG9 1.5583 | MUL1 1.5551 | PKN1 1.5412 | MAP3K6 1.5004 | DAB2IP 1.4910 | IL1A 1.4740 | MINK1 1.4611 | RIPK2 1.4586 | SFRP4 1.4173 | LTBR 1.3929 | DUSP3 1.3729 | WNT5A 1.3655 | MDFIC 1.3332 | TRAF4 1.3222 | DUSP10 1.3025 | HDAC3 1.2916 | FLT4 1.2760 | DVL2 1.2681 | CCL19 1.2605 | CCL21 | TPD52L1 1.2547 | TAOK3 1.2239 | TNFRSF11A 1.2162 | ZEB2 1.2160 | PDCD4 1.2095 | ZNF675 1.1570 | FKTN 1.1433 | PAK1 1.1424 | PTK2B 1.1280 | CARD9 1.1237 | MAP4K4 1.1155 | TRAF6 1.1053 | IRAK1 1.0945 | CDC42 1.0907 | FCER1A 1.0656 | TRAF2 1.0448 | TLR3 1.0443 | PTPLAD1 1.0192 | NOD1 1.0056 | TLR4 0.9855 | CTGF 0.9616 | DUSP19 0.8851 | SDCBP 0.8733 | DBNL 0.8579 | EDA2R 0.8420 | MAP4K1 0.8117 | DVL3 0.7715 | DIXDC1 0.6947 | NOD2 0.6871 | ZNF622 0.6376 | ITCH 0.6286 | AIDA 0.6262 | WNT16 0.6218 | MLK4 | MLTK | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
forebrain cell migration (boxplot) | 39 | 39 | 3.1376597637760457 | 8.515121735027664E-4 | 0.02166921083195061 | 0.005235602094240838 | ARX 6.2843 | SLIT1 3.2641 | TNR 3.0413 | DAB1 2.9720 | NR2E1 2.8955 | SLIT2 2.8500 | EGFR 2.8090 | CXCL12 2.5696 | SLIT3 2.4489 | GLI3 2.3270 | RTN4 2.3237 | OGDH 2.3215 | CNTN2 2.2820 | RELN 2.2249 | ROBO1 2.1673 | LRP6 2.0780 | TYRO3 1.9521 | LRP8 1.6538 | EMX2 1.6232 | DRD2 1.5853 | LRRK2 1.5730 | FGFR1 1.5730 | CDK5 1.5715 | NDEL1 1.5703 | FOXB1 1.5142 | DRD1 1.4777 | POU3F2 1.4263 | AXL 1.4159 | PEX5 1.3972 | CX3CR1 1.2922 | POU3F3 1.1996 | SRF 1.1778 | LHX6 1.0642 | PSEN1 1.0274 | CDK5R1 0.9094 | PAFAH1B1 0.8148 | NKX2-1 0.7775 | PEX13 0.7502 | DIXDC1 0.6947 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of lymphocyte differentiation (boxplot) | 60 | 60 | 3.1336770690323106 | 8.631536355039326E-4 | 0.021851651104001113 | 0.005208333333333333 | HLA-DMA 4.6143 | BTK 4.4391 | CD27 4.1635 | AP3B1 3.4690 | INPP5D 3.1650 | SOCS5 3.0169 | ITPKB 2.8294 | CD83 2.8181 | IL2RA 2.7760 | PNP 2.7166 | IL15RA 2.4319 | PRDM1 2.3377 | GLI3 2.3270 | NKAP 2.2960 | IL15 2.2242 | VNN1 2.1790 | IKZF1 2.1588 | SYK 2.1149 | CD80 1.9711 | GAS6 1.9676 | CD86 1.9313 | SART1 1.9142 | HLX 1.8571 | IL12RB1 1.8501 | PRKCZ 1.7929 | MYB 1.7428 | IL6 1.7153 | BAD 1.6791 | IL4 1.6202 | TGFBR2 1.5967 | GATA3 1.5648 | FOXP3 1.5343 | ADAM8 1.5178 | HLA-G 1.5161 | STAT5A 1.5114 | IL23R 1.4973 | GIMAP5 1.4739 | RIPK2 1.4586 | ADA 1.4333 | PTPRC 1.4182 | AXL 1.4159 | ZAP70 1.3847 | LILRB2 1.3636 | GLI2 1.3606 | LCK 1.3129 | IL2 1.2715 | CCL19 1.2605 | NCKAP1L 1.2593 | SHH 1.2438 | SASH3 1.1258 | IHH 1.1219 | IL7R 1.1090 | IL7 1.0414 | CD74 1.0390 | RARA 1.0131 | STAT5B 1.0063 | TNFSF4 0.9088 | IL12B 0.7568 | IL23A 0.7358 | IL21 0.6433 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cholesterol transporter activity (boxplot) | 13 | 13 | 3.133300566311803 | 8.642616954681603E-4 | 0.021851651104001113 | 0.0051813471502590676 | ABCA1 5.6064 | STARD3 3.2295 | APOA1 3.0248 | APOA4 2.5911 | ABCG4 2.1882 | ABCG1 2.0741 | CETP 1.6214 | ABCG5 1.4958 | ABCG8 1.4958 | STAR 1.4812 | APOE 1.4398 | APOB 1.2451 | APOA2 0.8951 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of metal ion transport (boxplot) | 177 | 177 | 3.130590924829198 | 8.72274923627403E-4 | 0.021856078342787133 | 0.005154639175257732 | SCN3B 4.2468 | AQP2 4.0312 | CAV1 3.7656 | GNAO1 3.7443 | INPP5K 3.5378 | KCNA5 3.3453 | MYLK 3.2871 | RYR2 3.1737 | CACNB4 3.1376 | EFCAB4B 2.9151 | CACNA1C 2.8754 | SIK1 2.8664 | OPRM1 2.8228 | SLC8A1 2.7718 | LACRT 2.7283 | CACNG3 2.6709 | F2 2.6432 | LIME1 2.6410 | YWHAH 2.6079 | PKD2L1 2.5895 | CXCL12 2.5696 | CAMK2D 2.5615 | ADCYAP1R1 2.5080 | TPCN2 2.5016 | STIM1 2.4544 | PLCG2 2.4205 | SCNN1B 2.4026 | SESTD1 2.4004 | VDR 2.3912 | CAV3 2.3881 | P2RX5 2.3388 | NEDD4L 2.3099 | NOS1 2.3035 | SCN5A 2.2668 | AGT 2.2659 | CACNG4 2.2546 | CAMK2B 2.2519 | NKX2-5 2.2385 | GLP1R 2.2306 | CACNB2 2.2123 | HOMER1 2.1943 | EGF 2.1937 | CAMK2G 2.1818 | JPH3 2.1788 | BCL2 2.1766 | CACNA1D 2.1182 | AKT1 2.1144 | RHOC 2.1005 | RCVRN 2.0984 | CACNA1E 2.0970 | CCKAR 2.0865 | SLC30A1 2.0329 | IL1RAPL1 2.0206 | CACNA2D1 1.9982 | PKD2 1.9879 | SNCA 1.9846 | NEDD4 1.9836 | PTGS2 1.9806 | GAS6 1.9676 | CACNG7 1.9540 | P2RX1 1.9501 | DRD3 1.9435 | JPH1 1.9422 | OPRD1 1.9420 | ASPH 1.9379 | CACNA1A 1.9305 | CCL4 1.9161 | SLN 1.8957 | STK39 1.8938 | JAK3 1.8666 | P2RX7 1.8574 | CACNA1B 1.8481 | CACNG1 1.8336 | DRD4 1.8319 | MGEA5 1.8243 | FFAR1 1.8156 | CCL5 1.8122 | AKT2 1.7769 | ZP3 1.7758 | LHCGR 1.7607 | ITGAV 1.7509 | ABCC8 1.7488 | SLC9A3 1.7279 | ADORA1 1.7070 | CASQ1 1.6978 | CACNG6 1.6930 | CACNG5 1.6745 | ICAM1 1.6718 | NOS3 1.6288 | TRPC4 1.6274 | SERPINE2 1.6272 | NCS1 1.6216 | CNKSR3 1.6120 | CACNA1I 1.6100 | ADRB1 1.6047 | LYN 1.5986 | WFS1 1.5881 | DRD2 1.5853 | HTR2A 1.5850 | CAPN3 1.5788 | WNK2 1.5580 | RYR1 1.5561 | MYO5A 1.5529 | TRIM27 1.5287 | GJA1 1.5265 | P2RX4 1.5095 | DRD1 1.4777 | F2RL3 1.4758 | GIMAP5 1.4739 | STIM2 1.4476 | ACTN4 1.4437 | TRPC6 1.4311 | F2R 1.4291 | MS4A2 1.4184 | CACNA1S 1.3954 | P2RX3 1.3783 | FKBP1A 1.3770 | CACNG2 1.3692 | LILRB2 1.3636 | PLCB4 1.3630 | DIAPH1 1.3602 | PML 1.3600 | SCN1B 1.3219 | TRPC3 1.3214 | FKBP1B 1.3101 | ADORA2A 1.3027 | CACNG8 1.2699 | PDGFRB 1.2307 | CCR1 1.2203 | SCN4B 1.2124 | GCG 1.2112 | CASR 1.2002 | XCL1 1.1948 | LPAR3 1.1870 | CACNB1 1.1775 | PLCG1 1.1759 | ADRA2A 1.1742 | TSPO 1.1685 | MCHR1 1.1656 | TRPV2 1.1404 | JPH2 1.1317 | PTK2B 1.1280 | CALM2 1.1102 | ATP1A1 1.0906 | GRIN3B 1.0627 | SCN2B 1.0517 | ADRB2 1.0467 | BDKRB1 1.0309 | PDGFB 1.0240 | CREB3 0.9695 | TGFB1 0.9693 | WNK3 0.9692 | TRPC1 0.9629 | CACNA1F 0.9583 | CCL3 0.9396 | PLN 0.9193 | DMPK 0.8803 | IL13 0.8304 | TMEM66 0.8252 | CALCA 0.8098 | EDNRA 0.8058 | RANGRF 0.7954 | BAK1 0.7850 | KCNE3 0.7603 | LILRB1 0.7574 | CACNB3 0.7536 | AHCYL1 0.7381 | SLC9A3R1 0.7026 | P2RX2 0.6514 | THY1 0.6002 | ORAI1 0.5808 | HCRT 0.5645 | GNAI2 0.5640 | CTNNB1 0.5466 | EPO 0.4955 | PLA2G1B 0.4953 | JPH4 0.4863 | ||||||||||||||||||||||||||||||
phosphatidylinositol binding (boxplot) | 147 | 150 | 3.120775317716186 | 9.018779957999934E-4 | 0.022482530038156978 | 0.005128205128205128 | BTK 4.4391 | BBS5 3.9745 | PICALM 3.8576 | ARAP1 3.7330 | PIK3C2G 3.7146 | HIP1 3.4696 | SNX19 3.3443 | MARK1 3.3006 | FES 3.1088 | MPPE1 3.0690 | ZFYVE28 2.8529 | ING2 2.8259 | SNX30 2.7690 | CCDC88A 2.7048 | SYT1 2.6792 | SCARB1 2.6205 | PLCB1 2.6151 | MYO1E 2.5057 | SNX5 2.4768 | WDR45L 2.4644 | SBF2 2.4546 | SNAP91 2.4483 | INPPL1 2.4159 | SESTD1 2.4004 | ARAP2 2.3911 | ARAP3 2.3645 | ZFYVE9 2.3480 | PLD2 2.2800 | SGK1 2.2618 | SYTL2 2.2517 | GAB2 2.2298 | COL4A3BP 2.2085 | VNN1 2.1790 | PASK 2.1664 | ITPR2 2.1594 | SNX29 2.1455 | AKT1 2.1144 | FAM123A 2.0978 | TWF2 2.0553 | APBA1 2.0498 | PARD3 2.0430 | MYO1B 2.0278 | PLEKHA4 2.0139 | SH3PXD2A 2.0033 | RAB35 1.9916 | SNX27 1.9883 | WIPI1 1.9855 | CLVS1 1.9822 | SNX1 1.9744 | SNX22 | EEA1 1.9640 | CYTH3 1.9639 | TULP3 1.9626 | TWF1 1.9582 | TULP1 1.9365 | PLEKHA5 1.8999 | NISCH 1.8699 | SNX21 1.8577 | PIK3R1 1.8351 | SEPT12 1.8144 | VPS36 1.8104 | DAPP1 1.7926 | MYO10 1.7867 | ITPR3 1.7657 | PLD1 1.7651 | KIF16B 1.7533 | SNX17 1.7419 | VIL1 1.7405 | PFN2 1.7072 | ADAP2 1.6995 | SNX10 1.6960 | PLEKHA2 1.6788 | WDFY1 1.6773 | SCIN 1.6737 | ARHGAP32 1.6693 | RPH3A 1.6628 | SNX33 1.6460 | TIRAP 1.6414 | SNX8 1.6310 | ZCCHC14 1.6307 | PIGK 1.6151 | SNX9 1.5729 | ZFYVE26 1.5697 | FRMPD4 1.5631 | MCF2L 1.5518 | SNX12 1.5426 | MTM1 1.5088 | ARHGAP33 1.4921 | SNX4 1.4884 | ITPR1 1.4342 | HIP1R 1.4332 | LDLRAP1 1.4279 | NOXO1 1.4144 | SNX20 1.4142 | SNX25 1.4119 | ANXA2 1.4037 | SNX7 1.4001 | PIK3C2B 1.3906 | EPB41 1.3904 | WDFY3 1.3854 | HS1BP3 1.3737 | FCHO2 1.3684 | PLEKHA3 1.3612 | DPEP1 1.3546 | NCF4 1.3088 | PHLDA3 1.3045 | SNX32 1.2856 | RPS6KC1 1.2836 | WIPI2 1.2830 | PLEK 1.2748 | SNX31 1.2681 | TECPR1 1.2296 | FRMPD2 1.2268 | SNX11 1.2185 | DOK7 1.2147 | SNX24 1.2072 | PLEKHA1 1.2069 | SNX3 1.1873 | GRB7 1.1828 | SGK3 1.1609 | SNX14 1.1463 | SNX18 1.0994 | PXK 1.0895 | CHMP3 1.0654 | PXDC1 1.0556 | NCF1 1.0210 | CLVS2 1.0016 | SNX2 0.9583 | SH3PXD2B 0.9550 | SNX6 0.9439 | ZCCHC2 0.9370 | GPAA1 0.9009 | PIK3C2A 0.8669 | SNX13 0.8561 | ZFYVE1 0.8202 | LANCL2 0.7974 | FAM123B 0.7822 | ZFYVE16 0.7664 | PIGU 0.7475 | PHF12 0.6746 | OGT 0.6705 | SNX16 0.6631 | RAG2 0.6482 | ANXA2P2 0.6424 | SNX15 0.6347 | THY1 0.6002 | WDR45 0.4823 | NCF1C 0.1306 | A-388D4.1 | NCF1B | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cellular response to insulin stimulus (boxplot) | 28 | 29 | 3.1194538976086355 | 9.059330611210781E-4 | 0.022482530038156978 | 0.00510204081632653 | SIRT1 7.4176 | INPP5K 3.5378 | PRKCB 2.9939 | PID1 2.9916 | SIK2 2.5468 | PTPRF 2.5339 | INPPL1 2.4159 | GRB10 2.0523 | SOCS1 1.9877 | IGF2 1.9742 | INS | IRS1 1.9115 | IL1B 1.8813 | AHSG 1.8397 | PRKCZ 1.7929 | RELA 1.6587 | PTPRE 1.6062 | PRKCQ 1.5129 | GRB14 1.4400 | PTPN1 1.4205 | LEP 1.4143 | RPS6KB1 1.2260 | GSK3A 1.2130 | ENPP1 1.1901 | SOCS3 1.1324 | GPLD1 1.0747 | TSC2 1.0731 | PRKCD 1.0164 | OGT 0.6705 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of receptor-mediated endocytosis (boxplot) | 37 | 39 | 3.117948138770823 | 9.105742313175735E-4 | 0.022482530038156978 | 0.005076142131979695 | BICD1 4.2108 | PICALM 3.8576 | HIP1 3.4696 | MAGI2 3.4637 | VEGFA 3.0488 | APOC3 3.0248 | RSPO1 2.8111 | APOA5 2.5911 | SERPINE1 2.3072 | PLD2 2.2800 | SH3GL2 2.0435 | SCYL2 2.0365 | ATAD1 2.0096 | CBL 1.9784 | RAC1 1.9125 | GH1 1.8449 | VTN 1.8442 | PPT1 1.7921 | SYNJ2BP 1.7375 | SGIP1 1.7021 | GREM1 1.6695 | WNT3A 1.6407 | DRD2 1.5853 | PCSK9 1.4808 | LDLRAP1 1.4279 | SFRP4 1.4173 | APOC1 1.3441 | APOC2 | CCL19 1.2605 | CCL21 | SELE 1.1773 | DKK1 1.1626 | ARF6 1.1563 | ATXN2 1.1522 | ANGPT1 1.1416 | HNRNPK 1.0984 | MTMR2 1.0519 | AHI1 0.9870 | SYNJ1 0.6101 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lipid transporter activity (boxplot) | 64 | 64 | 3.114279889123353 | 9.219724030515852E-4 | 0.022636970659849476 | 0.005050505050505051 | ABCA1 5.6064 | ATP9A 3.8389 | PITPNC1 3.8379 | ATP11A 3.7283 | ATP8A2 3.6048 | FABP1 3.5813 | STARD3 3.2295 | ATP8B2 3.0740 | APOA1 3.0248 | PITPNM3 2.8095 | PITPNA 2.6811 | APOA4 2.5911 | PITPNB 2.3808 | GLTPD2 2.2800 | ATP10D 2.2069 | ATP10A 2.1905 | ABCG4 2.1882 | SLC27A5 2.1872 | APOM 2.1586 | SLCO2A1 2.1406 | PLEKHA8 2.1130 | PLSCR4 2.0968 | ABCG1 2.0741 | ATP8B4 1.9597 | SLC27A4 1.9556 | ABCA4 1.9148 | ATP9B 1.7613 | CFHR4 1.7519 | GLTP 1.7122 | APOD 1.6583 | SLC27A2 1.6261 | CETP 1.6214 | ATP10B 1.5905 | APOL6 1.5397 | PITPNM1 1.5262 | ABCG5 1.4958 | ABCG8 1.4958 | STAR 1.4812 | APOE 1.4398 | FABP3 1.4047 | ATP8B1 1.3825 | APOC4 1.3441 | SLC27A1 1.3359 | ATP11B 1.2915 | ABCA7 1.2907 | GLTPD1 1.2902 | PLEKHA8P1 1.2797 | ATP8A1 1.2627 | APOB 1.2451 | MTTP 1.2284 | PCTP 1.1922 | ATP8B3 0.9821 | PLSCR1 0.9775 | NPC1 0.9459 | PLSCR2 0.9222 | APOA2 0.8951 | PLSCR3 0.8330 | APOL3 0.7791 | SFTPA1 0.7503 | APOF 0.7358 | RFT1 0.6735 | ATP11C 0.5439 | ABCD1 0.5027 | FABP2 0.4716 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
transmembrane receptor protein tyrosine phosphatase activity (boxplot) | 18 | 18 | 3.108677433545387 | 9.396338366038925E-4 | 0.022955254628233095 | 0.005025125628140704 | PTPRD 3.6941 | PTPRS 3.0117 | PTPRN2 2.8388 | PTPRK 2.7450 | PTPRM 2.7283 | PTPRF 2.5339 | PTPRG 2.3556 | PTPRU 2.2077 | PTPRB 2.0671 | PTPRA 2.0157 | PTPRO 1.7894 | PTPRN 1.7755 | PTPRE 1.6062 | PTPRR 1.4415 | PTPRC 1.4182 | PTPRH 1.2326 | PTPN6 1.1681 | PTPRZ1 0.9164 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
transmembrane receptor protein phosphatase activity (boxplot) | 18 | 18 | 3.108677433545387 | 9.396338366038925E-4 | 0.022955254628233095 | 0.005025125628140704 | PTPRD 3.6941 | PTPRS 3.0117 | PTPRN2 2.8388 | PTPRK 2.7450 | PTPRM 2.7283 | PTPRF 2.5339 | PTPRG 2.3556 | PTPRU 2.2077 | PTPRB 2.0671 | PTPRA 2.0157 | PTPRO 1.7894 | PTPRN 1.7755 | PTPRE 1.6062 | PTPRR 1.4415 | PTPRC 1.4182 | PTPRH 1.2326 | PTPN6 1.1681 | PTPRZ1 0.9164 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
antigen receptor-mediated signaling pathway (boxplot) | 103 | 114 | 3.1001715269043393 | 9.670430148127629E-4 | 0.023390951338490888 | 0.004975124378109453 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | BTK 4.4391 | FYN 3.7055 | PSEN2 3.3139 | INPP5D 3.1650 | MAP3K7 3.1402 | CARD11 3.1018 | SPG21 3.0724 | PRKCB 2.9939 | NFATC2 2.9629 | LAT 2.8728 | THEMIS 2.7728 | CD19 2.7102 | TEC 2.6652 | LIME1 2.6410 | HLA-DMB 2.6120 | PIK3CD 2.5941 | TXK 2.5595 | RBCK1 2.4349 | PLCG2 2.4205 | SKAP1 2.4173 | HLA-DQA1 2.3613 | NFKBIA 2.3376 | IKBKG 2.2420 | KLHL6 2.2407 | BCL2 2.1766 | RPS27A 2.1523 | HLA-DRB1 2.1516 | CD3D 2.1205 | CD3E 2.1205 | CD3G | SYK 2.1149 | MEF2C 2.0426 | CD4 2.0421 | MAPK1 1.9571 | PAG1 1.9087 | ENAH 1.8839 | CD38 1.8553 | VAV3 1.8406 | PIK3R1 1.8351 | HLA-DRB5 1.8305 | HLA-DQB1 1.7437 | GRAP2 1.7178 | PAK2 1.7086 | TAB2 1.6659 | RELA 1.6587 | BCAR1 1.6063 | LYN 1.5986 | HLA-DOB 1.5897 | GATA3 1.5648 | HLA-DQA2 1.5353 | HLA-DQB2 | FOXP3 1.5343 | PRKCQ 1.5129 | HLA-DPA1 1.4883 | HLA-DPB1 | NFKB1 1.4613 | RIPK2 1.4586 | PDPK1 1.4292 | PTPN22 1.4217 | PTPRC 1.4182 | ZAP70 1.3847 | PTEN 1.3846 | SH2B2 1.3733 | LAT2 1.3653 | VASP 1.3560 | SLA2 1.3387 | MALT1 1.3374 | PIK3CA 1.3325 | UBC 1.3324 | LCK 1.3129 | UBA52 1.2944 | RNF31 1.2821 | HLA-DRA 1.2787 | CD247 1.2624 | NCKAP1L 1.2593 | PIK3R2 1.2583 | HLA-DRB3 1.2503 | UBE2V1 1.2308 | PLEKHA1 1.2069 | CHUK 1.1789 | PLCG1 1.1759 | PAK1 1.1424 | FYB 1.1186 | MNDA 1.1179 | WAS 1.1123 | TRAF6 1.1053 | CSK 1.0827 | ITK 1.0826 | CTLA4 1.0433 | BLK 1.0417 | PSEN1 1.0274 | LCP2 0.9459 | PIK3CB 0.9249 | CD79A 0.8908 | TRAT1 0.8232 | BCL10 0.8189 | NFAM1 0.7992 | CACNB3 0.7536 | IKBKB 0.7521 | UBB 0.7504 | NCK1 0.7460 | UBE2N 0.7395 | THY1 0.6002 | PRKD2 0.5986 | HLA-DRB4 | P01737 | P04436 | TCRA | TCRB | TRAC | TRBC1 | TRBV12-3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of axonogenesis (boxplot) | 96 | 97 | 3.0958404813062255 | 9.81279554190917E-4 | 0.023618383752595173 | 0.0049504950495049506 | DCC 5.1066 | NTRK3 4.8124 | CDH2 3.9744 | SLIT1 3.2641 | SCARF1 3.2573 | MBP 3.0687 | TNR 3.0413 | CDH4 3.0350 | ROBO2 3.0085 | LRRC4C 2.9758 | XYLT1 2.9735 | DAB1 2.9720 | SLIT2 2.8500 | TIAM1 2.8400 | NTRK2 2.7766 | PLXNB2 2.7490 | EPHB2 2.7088 | DSCAM 2.5746 | CXCL12 2.5696 | MT3 2.3391 | BCL11A 2.3352 | RTN4 2.3237 | TNFRSF12A 2.3109 | CNTN2 2.2820 | NGFR 2.2572 | MAP1B 2.2447 | STK25 2.1927 | ROBO1 2.1673 | SPP1 2.1654 | FXN 2.1599 | WNT3 2.0876 | WNT7A 2.0616 | TWF2 2.0553 | NGF 2.0438 | RUFY3 2.0308 | ISLR2 2.0308 | CACNA1A 1.9305 | RNF6 1.9069 | RHOA 1.8947 | MAG 1.8819 | PTPRO 1.7894 | ANAPC2 1.7859 | KIF13B 1.6972 | RYK 1.6892 | SEMA3A 1.6808 | EPHA4 1.6721 | WNT3A 1.6407 | MARK2 1.6028 | NDEL1 1.5703 | ADNP 1.5371 | NRCAM 1.5362 | NEFM 1.5303 | EP300 1.4888 | CHN1 1.4789 | AMIGO1 1.4658 | APOE 1.4398 | STK24 1.4284 | POU3F2 1.4263 | KLK8 1.4015 | SEMA4D 1.3860 | PTEN 1.3846 | PTK2 1.3822 | WNT5A 1.3655 | EFNA1 1.2501 | SEMA3F 1.2271 | SSH1 1.2178 | SEMA4F 1.2167 | NTN1 1.2089 | LIMK1 1.1825 | SYNGAP1 1.1743 | STK11 1.1724 | TRPV2 1.1404 | ILK 1.1347 | BARHL2 1.1224 | RTN4R 1.1144 | SIPA1L1 1.1047 | SSH3 1.1031 | PSEN1 1.0274 | CDKL5 1.0190 | ACHE 0.9394 | ULK1 0.9247 | ARHGEF1 0.8908 | CNTF 0.8746 | LINGO1 0.8604 | PAFAH1B1 0.8148 | SSH2 0.7923 | OMG 0.7849 | SKIL 0.7578 | SEMA7A 0.7223 | DIXDC1 0.6947 | PLXNB1 0.6552 | ARHGDIA 0.6161 | EPHB3 0.6149 | THY1 0.6002 | TTL 0.4819 | MAPT 0.4387 | DKFZp434G0625 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
behavioral interaction between organisms (boxplot) | 55 | 56 | 3.090493552347025 | 9.991207155684023E-4 | 0.023929920667976536 | 0.0049261083743842365 | NRXN1 3.6097 | NPAS3 3.5151 | SHANK1 3.1256 | ANXA7 2.9900 | DNAJC9 2.9727 | NR2E1 2.8955 | HRAS 2.6539 | MSS51 2.4174 | PPP3CB 2.4174 | OXTR 2.3881 | HEXB 2.3391 | UBR3 2.3189 | PHF21A 2.3164 | NLGN4X 2.3043 | GRIN2B 2.2951 | SLC6A4 2.2725 | APP 2.1303 | SHANK3 2.0446 | CNTFR 2.0310 | APLP2 2.0226 | HTT 2.0106 | TH 1.9742 | DRD3 1.9435 | AVP 1.9195 | OXT | IL1B 1.8813 | GCNT4 1.8774 | TBX1 1.8661 | MAPK8IP2 1.8627 | DRD4 1.8319 | GNB1L 1.8155 | DBH 1.8135 | PPP1R1B 1.8013 | DLG4 1.7370 | MTNR1A 1.7179 | HELT 1.7166 | NLGN3 1.5936 | CYP11A1 1.5384 | MKKS 1.5151 | DRD1 1.4777 | CLN8 1.4407 | PTEN 1.3846 | TACR1 1.3533 | DRD5 1.2989 | DVL1 1.2676 | GRPR 1.2039 | HAND2 1.1943 | CRHBP 1.0855 | VPS13A 1.0804 | THRA 1.0727 | POU4F1 1.0505 | KRAS 0.9975 | CHRNB2 0.9425 | PEX13 0.7502 | AVPR1A 0.6808 | NHLH2 0.4876 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
neurotransmitter secretion (boxplot) | 68 | 70 | 3.087869662188908 | 0.001007984339520096 | 0.024024446258025314 | 0.004901960784313725 | VAMP1 4.1635 | PCLO 4.0360 | CPLX2 3.2544 | NLGN1 2.7866 | PPFIA3 2.7612 | CHAT 2.7603 | SLC18A3 | STX1A 2.7012 | XBP1 2.6965 | SNPH 2.6851 | SYN2 2.6795 | SYT1 2.6792 | STXBP1 2.6367 | SPTBN2 2.5986 | CADPS 2.5522 | HRH3 2.5237 | SEPT5 2.2712 | SLC22A2 2.2511 | GLS 2.1689 | SLC18A2 2.0880 | SYN3 2.0801 | WNT7A 2.0616 | BAIAP3 2.0183 | RIMS1 1.9395 | AP2B1 1.9360 | CACNA1A 1.9305 | UNC13B 1.8915 | SYT4 1.8726 | P2RX7 1.8574 | SLC5A7 1.8496 | CACNA1B 1.8481 | PPT1 1.7921 | GRM4 1.7819 | SLC17A7 1.7655 | SLC6A12 1.7455 | PIP5K1C 1.7353 | BRSK1 1.7013 | CPLX1 1.6807 | UNC13A 1.6800 | DOC2B 1.6682 | OTOF 1.6397 | SLC32A1 1.6305 | SLC38A2 1.5792 | CDK5 1.5715 | SLC6A11 1.5526 | DOC2A 1.5395 | SYN1 1.4729 | SLC6A1 1.4647 | SNAP25 1.4539 | RAB3A 1.4334 | ABAT 1.3792 | SNAPIN 1.3340 | HSPA8 1.2788 | DNAJC5 1.2774 | DVL1 1.2676 | SYT2 1.2635 | GLS2 1.2509 | CPLX3 1.1056 | PLDN 1.1027 | GAD1 1.0859 | ALDH5A1 1.0747 | VAMP2 1.0699 | PSEN1 1.0274 | SLC6A13 1.0084 | GAD2 0.8924 | RAB14 0.7921 | STX4 0.6681 | SYNJ1 0.6101 | MAOA 0.3928 | F5H0A2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of lipid transport (boxplot) | 54 | 56 | 3.085610326304592 | 0.0010156742379636707 | 0.0240902151781092 | 0.004878048780487805 | SIRT1 7.4176 | ABCA1 5.6064 | PLA2R1 3.4416 | APOA1 3.0248 | APOC3 | SREBF2 2.9595 | PTCHD2 2.7324 | APOA4 2.5911 | NFKBIA 2.3376 | EGF 2.1937 | NCOR1 2.1739 | ITGB3 2.1729 | SYK 2.1149 | AKT1 2.1144 | PTCH1 2.1082 | ABCG1 2.0741 | ACSL5 2.0627 | OXT 1.9195 | IL1B 1.8813 | LRP1 1.8683 | P2RX7 1.8574 | IRS2 1.8084 | AKT2 1.7769 | PLA2G10 1.7764 | ITGAV 1.7509 | TNFSF11 1.7065 | CYP4A11 1.6857 | PPARG 1.6692 | CETP 1.6214 | PON1 1.5922 | P2RX4 1.5095 | ABCG5 1.4958 | ABCG8 1.4958 | NFKB1 1.4613 | APOE 1.4398 | P2RY2 1.4186 | LEP 1.4143 | ABCA2 1.4115 | LAMTOR1 1.3465 | APOC1 1.3441 | APOC2 | ADIPOQ 1.3289 | NR1H3 1.3265 | LIPG 1.3223 | SHH 1.2438 | TNFRSF11A 1.2162 | TSPO 1.1685 | NR1H2 1.1632 | HNRNPK 1.0984 | IRAK1 1.0945 | CYP4F2 1.0426 | PPARA 1.0266 | PRKCD 1.0164 | APOA2 0.8951 | THBS1 0.7292 | GDF9 0.4597 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
adherens junction (boxplot) | 192 | 194 | 3.0828759089991995 | 0.0010250531142368402 | 0.024195215053918848 | 0.0048543689320388345 | LPP 4.0845 | CDH2 3.9744 | CAV1 3.7656 | MAP2K2 3.3627 | AJAP1 3.2954 | NF2 3.2554 | PARVA 3.2150 | CTNNA3 3.1603 | ACTN3 3.1352 | FES 3.1088 | AFAP1 3.0330 | KIFC3 2.9206 | TLN2 2.8514 | FMN1 2.7977 | BSPRY 2.7881 | NRAP 2.7788 | SHROOM3 2.7639 | PTPRK 2.7450 | PTPRM 2.7283 | PARVG 2.7255 | SMPX 2.6933 | FHL2 2.6776 | PARVB 2.6643 | KIAA1462 2.6512 | STARD8 2.5619 | ZYX 2.5465 | ARHGAP26 2.5226 | APBB1IP 2.5101 | MYO1E 2.5057 | CTNND2 2.4273 | IRF2 2.4245 | OXTR 2.3881 | CTNNA2 2.3669 | PDLIM2 2.3613 | SORBS3 | FAT2 2.3507 | DLG5 2.3420 | ZNF384 2.3418 | FAM129B 2.3345 | LASP1 2.3015 | DLC1 2.2963 | KIF22 2.2825 | MPP7 2.2168 | CXADR 2.1888 | PRUNE 2.1770 | FERMT1 2.1644 | SHROOM2 2.1572 | PLEKHA7 2.1105 | NDRG1 2.0974 | LIMA1 2.0815 | ITGB5 2.0784 | LIG4 2.0575 | XIRP1 2.0504 | PARD3 2.0430 | ACTN1 2.0386 | TENC1 2.0361 | ARHGAP31 2.0298 | LUC7L3 2.0278 | TRPV4 2.0262 | FOCAD 2.0151 | ARHGAP24 2.0128 | VEZT 2.0093 | TGM1 2.0083 | NEDD9 1.9952 | SRCIN1 1.9663 | MAPK1 1.9571 | GIT1 1.9371 | EPHX2 1.9171 | SCRIB 1.9095 | JUP 1.9019 | RFWD2 1.8935 | ENAH 1.8839 | TEK 1.8630 | MAPK3 1.8628 | DLG1 1.8617 | CASS4 1.8595 | TBCD 1.8480 | SYNE2 1.8459 | PEAK1 1.8398 | NOX4 1.8368 | MYH6 1.8142 | MYH7 1.8142 | PPP1R9B 1.8018 | ADAM15 1.7569 | ABI2 1.7385 | PIP5K1C 1.7353 | NEXN 1.7265 | RHOU 1.7224 | ACTN2 1.7215 | PVRL2 1.7152 | VCL 1.7125 | BRCA1 1.7066 | PGM5 1.7013 | TJP2 1.6818 | GAK 1.6807 | SORBS1 1.6523 | DSC2 1.6288 | TNS1 1.6163 | TPPP 1.6115 | BCAR1 1.6063 | CAMSAP3 1.6054 | KEAP1 1.5752 | PALLD 1.5733 | NEURL2 1.5580 | PVRL1 1.5566 | LIMS1 1.5517 | SH3KBP1 1.5425 | MAP2K1 1.5376 | ITGA2B 1.5355 | TNK2 1.5282 | GJA1 1.5265 | APC 1.5096 | ADAM17 1.5056 | FERMT2 1.4965 | LMLN 1.4802 | HCK 1.4790 | SMAD7 1.4674 | PPAP2B 1.4601 | FGFR3 1.4587 | TNS3 1.4439 | PDPK1 1.4292 | PTPRC 1.4182 | CIDEC 1.4018 | PTK2 1.3822 | LIMS2 1.3778 | PDLIM7 1.3736 | TRIP6 1.3664 | CTNNA1 1.3657 | VASP 1.3560 | AJUBA 1.3552 | DES 1.3358 | PLEC 1.3309 | LIMD1 1.2921 | SDC4 1.2900 | EVL 1.2888 | PKP2 1.2815 | MDC1 1.2721 | ESAM 1.2599 | SIKE1 1.2553 | TJP1 1.2276 | CDH1 1.2150 | GRB7 1.1828 | LIMK1 1.1825 | EPHA2 1.1715 | MYH9 1.1496 | PAK1 1.1424 | ILK 1.1347 | EZR 1.1330 | RDX 1.1316 | PTK2B 1.1280 | ARHGEF7 1.1278 | HIC2 1.1228 | ITGB1 1.1192 | PNMA1 1.1056 | LAYN 1.0936 | SYNM 1.0740 | CTNND1 1.0729 | SDC1 1.0557 | AIF1L 1.0549 | ZNF185 1.0454 | MLLT4 1.0402 | DSP 1.0262 | PXN 1.0115 | AHI1 0.9870 | TLN1 0.9695 | WNK3 0.9692 | CDH3 0.9414 | PVRL4 0.9395 | TMEM204 0.9252 | PVRL3 0.9077 | WTIP 0.9042 | ZFYVE21 0.8804 | ITGA6 0.8763 | EPB41L5 0.8760 | SDCBP 0.8733 | SSX2IP 0.8623 | RND1 0.8600 | TES 0.8392 | ITGA5 0.8380 | NPHP1 0.8245 | AATF 0.8142 | TGFB1I1 0.7938 | TNS4 0.7906 | ARHGAP4 0.7810 | MSN 0.7412 | DIXDC1 0.6947 | DAG1 0.6937 | CTNNB1 0.5466 | EBAG9 0.5301 | FBLIM1 0.5285 | LPXN 0.5113 | S100A7 0.4874 | ARPC2 0.4034 | C20orf42 | |||||||||||||
cell-substrate adhesion (boxplot) | 127 | 129 | 3.081590871670254 | 0.0010294880971456477 | 0.024195215053918848 | 0.004830917874396135 | TNN 4.2700 | ITGBL1 3.7597 | C22orf28 3.4290 | TAOK2 3.3686 | FBLN5 3.1469 | ACTN3 3.1352 | PPFIA1 3.0455 | COL13A1 2.7836 | TRPM7 2.7626 | VAMP3 2.7537 | PTPRK 2.7450 | PARVG 2.7255 | ITGA2 2.6856 | PRKX 2.6609 | JAM3 2.6353 | FREM1 2.6344 | EPHB1 2.6334 | ITGA1 2.5638 | EPHA1 2.5465 | MUC4 2.5381 | ITGB2 2.5057 | CD44 2.4166 | SIGLEC1 2.3633 | SORBS3 2.3613 | LAMA5 2.3426 | TNFRSF12A 2.3109 | DLC1 2.2963 | CNTN2 2.2820 | HPSE 2.2717 | AGT 2.2659 | ARHGAP6 2.1854 | BCL2 2.1766 | ITGB3 2.1729 | FZD7 2.1227 | PIP5K1A 2.0835 | ITGB5 2.0784 | LAMB1 2.0735 | NPNT 2.0460 | NID1 2.0430 | ACTN1 2.0386 | PPFIA2 2.0377 | ITGA10 2.0120 | GAS6 1.9676 | SRCIN1 1.9663 | ITGA8 1.9537 | TYRO3 1.9521 | RAPH1 1.9311 | FN1 1.9294 | LAMC1 1.9271 | ITGB6 1.9218 | RAC1 1.9125 | ANTXR1 1.9030 | FER 1.8987 | RHOA 1.8947 | SNED1 1.8800 | TEK 1.8630 | VTN 1.8442 | PEAK1 1.8398 | MERTK 1.8314 | THBS3 1.8194 | LYVE1 1.7915 | ADAM15 1.7569 | ITGAD 1.7565 | ITGAV 1.7509 | ACTN2 1.7215 | ITGA11 1.7210 | VCL 1.7125 | BRCA1 1.7066 | EDA 1.6572 | SORBS1 1.6523 | DDR1 1.6458 | NID2 1.5906 | TESK2 1.5784 | CDK5 1.5715 | PPARD 1.5657 | ITGA2B 1.5355 | COL3A1 1.4690 | COL17A1 1.4533 | PDPK1 1.4292 | TMEM8B 1.4208 | AXL 1.4159 | ANGPTL3 1.4147 | VWF 1.4032 | SMAD6 1.3786 | TRIP6 1.3664 | AJUBA 1.3552 | COL5A3 1.3492 | TSC1 1.3322 | ITGA3 1.3270 | ADAM9 1.3137 | CCL21 1.2605 | EFNA1 1.2501 | BCL2L11 1.2301 | GP5 1.2192 | ITGB7 1.1840 | SRF 1.1778 | TECTA 1.1635 | ANGPT1 1.1416 | SGCE 1.1407 | ILK 1.1347 | ITGA7 1.1296 | PTK2B 1.1280 | ITGB1 1.1192 | HOXD3 1.0955 | PXN 1.0115 | ADAMTS13 1.0115 | CORO1A 0.9727 | CTGF 0.9616 | BVES 0.9470 | EPDR1 0.9433 | CUZD1 0.9335 | CD34 0.9161 | ITGB4 0.8918 | PKD1 0.8841 | ITGB8 0.8819 | BCAM 0.8765 | ITGA6 0.8763 | EPB41L5 0.8760 | FXC1 0.7918 | ECM2 0.7676 | FZD4 0.7448 | DAG1 0.6937 | DEFB118 0.6419 | EPHB3 0.6149 | THY1 0.6002 | ITGB1BP1 0.5811 | CTNNB1 0.5466 | A8MZH7 | UCC1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
heparan sulfate proteoglycan metabolic process (boxplot) | 20 | 21 | 3.081038841825129 | 0.0010313986889964877 | 0.024195215053918848 | 0.004807692307692308 | HS3ST4 4.0952 | SULF2 3.5216 | HS6ST1 3.0605 | SULF1 2.9550 | HS3ST3B1 2.9193 | NDST4 2.6162 | CSGALNACT1 2.5188 | EXT1 2.2085 | NDST2 2.1818 | DSE 2.0810 | EXT2 1.9834 | NDST1 1.9496 | GPC1 1.4900 | B3GALT6 1.4593 | EXTL3 1.3288 | GLCE 1.2015 | HS2ST1 1.1877 | NDST3 0.9068 | EXTL2 0.8726 | HS3ST5 0.5510 | RP5-1049G16.1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
basal part of cell (boxplot) | 40 | 40 | 3.080323448037547 | 0.001033879527557069 | 0.024195215053918848 | 0.004784688995215311 | MYO1C 4.9972 | AQP5 4.0312 | CAV1 3.7656 | ADCY10 3.5194 | ERBB2 3.2295 | KCNQ4 2.8155 | ITGA2 2.6856 | ITGA1 2.5638 | TACSTD2 2.4154 | SLC27A5 2.1872 | SLC23A2 2.1821 | BMPR2 2.0562 | ACTR3 2.0099 | PKD2 1.9879 | CLCA2 1.9393 | JUP 1.9019 | HFE 1.8648 | TEK 1.8630 | ERBB2IP 1.8381 | AQP1 1.7153 | MYO1A 1.6056 | MARK2 1.6028 | AGER 1.5913 | MUC20 1.4838 | COL17A1 1.4533 | LDLRAP1 1.4279 | DOCK7 1.4147 | SLC16A8 1.3992 | DST 1.3319 | PLEC 1.3309 | SLC11A2 1.3019 | MET 1.1441 | ITGB1 1.1192 | CLDN4 1.1151 | OSCP1 0.9672 | SHROOM4 0.9493 | CD34 0.9161 | ITGB4 0.8918 | TF 0.8881 | ITGA6 0.8763 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sodium channel activity (boxplot) | 34 | 34 | 3.074514486043465 | 0.0010542274090380443 | 0.024412109576113197 | 0.004761904761904762 | SCN3B 4.2468 | SCN2A 3.6519 | ASIC2 2.7474 | SCN11A 2.6313 | PKD2L1 2.5895 | SCN9A 2.5308 | ASIC5 2.5107 | SCNN1B 2.4026 | SLC4A11 2.3045 | HCN1 2.2865 | SCN5A 2.2668 | SCN8A 2.1612 | SHROOM2 2.1572 | HCN2 2.0858 | NALCN 2.0487 | PKD2 1.9879 | SCN1A 1.8708 | ASIC1 1.8572 | SCNN1D 1.8009 | TRPM2 1.6363 | SCN10A 1.5853 | SCN7A 1.5790 | ASIC3 1.5715 | HCN4 1.5579 | SCNN1A 1.3929 | SCN3A 1.3785 | SCNN1G 1.3430 | SCN1B 1.3219 | ABP1 1.3087 | SCN4B 1.2124 | ASIC4 1.1569 | SCN2B 1.0517 | HCN3 0.8529 | SCN4A 0.8170 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cyclic-nucleotide phosphodiesterase activity (boxplot) | 25 | 27 | 3.061668944399243 | 0.0011005337080179922 | 0.025364187251773158 | 0.004739336492890996 | PDE2A 3.7330 | PDE10A 3.5081 | PDE4B 3.1574 | PDE8A 3.0407 | CNP 2.9419 | PDE11A 2.9328 | PDE4D 2.8834 | PDE7B 2.6103 | PDE3A 2.3821 | PDE6C 2.2565 | PDE1C 2.1963 | PDE9A 1.7763 | PDE3B 1.7081 | PDE6A 1.5259 | PDE1A 1.5160 | PDE4C 1.4334 | PDE6H 1.3989 | PDE8B 1.3712 | PDE7A 1.2485 | PDE1B 1.1847 | PDE6B 1.1598 | PDE5A 1.1185 | PDE6G 1.0776 | PDE6D 1.0743 | PDE4A 0.7502 | PDE4B5 | PDE7B variant protein | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cholesterol efflux (boxplot) | 19 | 21 | 3.0608679083463644 | 0.0011034821752625712 | 0.025364187251773158 | 0.0047169811320754715 | ABCA1 5.6064 | CAV1 3.7656 | SOAT1 3.1809 | APOA1 3.0248 | APOC3 | SCARB1 2.6205 | APOA4 2.5911 | ABCG4 2.1882 | APOM 2.1586 | ABCG1 2.0741 | NPC2 1.7277 | ABCG5 1.4958 | ABCG8 1.4958 | APOE 1.4398 | APOC1 1.3441 | APOC2 | ABCA5 1.2038 | NPC1 0.9459 | APOA2 0.8951 | SOAT2 0.7990 | STX12 0.6580 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
immune response-activating cell surface receptor signaling pathway (boxplot) | 112 | 123 | 3.0601836531265567 | 0.0011060065252006535 | 0.025364187251773158 | 0.004694835680751174 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | BTK 4.4391 | FYN 3.7055 | PSEN2 3.3139 | INPP5D 3.1650 | MAP3K7 3.1402 | CARD11 3.1018 | SPG21 3.0724 | PRKCB 2.9939 | NFATC2 2.9629 | LAT 2.8728 | THEMIS 2.7728 | MICB 2.7706 | CD19 2.7102 | TEC 2.6652 | LIME1 2.6410 | HLA-DMB 2.6120 | PIK3CD 2.5941 | TXK 2.5595 | KLRK1 2.5472 | RBCK1 2.4349 | PLCG2 2.4205 | SKAP1 2.4173 | HLA-DQA1 2.3613 | NFKBIA 2.3376 | IKBKG 2.2420 | KLHL6 2.2407 | MICA 2.1925 | BCL2 2.1766 | RPS27A 2.1523 | HLA-DRB1 2.1516 | CD3D 2.1205 | CD3E 2.1205 | CD3G | SYK 2.1149 | MEF2C 2.0426 | CD4 2.0421 | MAPK1 1.9571 | PAG1 1.9087 | ENAH 1.8839 | CD38 1.8553 | VAV3 1.8406 | PIK3R1 1.8351 | HLA-DRB5 1.8305 | HLA-DQB1 1.7437 | GRAP2 1.7178 | PAK2 1.7086 | TAB2 1.6659 | RELA 1.6587 | BCAR1 1.6063 | LYN 1.5986 | HLA-DOB 1.5897 | GATA3 1.5648 | HLA-DQA2 1.5353 | HLA-DQB2 | FOXP3 1.5343 | PRKCQ 1.5129 | HLA-DPA1 1.4883 | HLA-DPB1 | NFKB1 1.4613 | RIPK2 1.4586 | PDPK1 1.4292 | PTPN22 1.4217 | PTPRC 1.4182 | CLEC7A 1.3986 | ZAP70 1.3847 | PTEN 1.3846 | SH2B2 1.3733 | TLR2 1.3663 | LAT2 1.3653 | VASP 1.3560 | SLA2 1.3387 | MALT1 1.3374 | PIK3CA 1.3325 | UBC 1.3324 | LCK 1.3129 | UBA52 1.2944 | RNF31 1.2821 | HLA-DRA 1.2787 | CD247 1.2624 | NCKAP1L 1.2593 | PIK3R2 1.2583 | CR2 1.2526 | HLA-DRB3 1.2503 | UBE2V1 1.2308 | PLEKHA1 1.2069 | C3AR1 1.2032 | CHUK 1.1789 | PLCG1 1.1759 | PAK1 1.1424 | FYB 1.1186 | MNDA 1.1179 | WAS 1.1123 | TRAF6 1.1053 | CSK 1.0827 | ITK 1.0826 | GPLD1 1.0747 | CTLA4 1.0433 | BLK 1.0417 | PSEN1 1.0274 | LCP2 0.9459 | PIK3CB 0.9249 | FCER1G 0.8951 | CD79A 0.8908 | TRAT1 0.8232 | BCL10 0.8189 | NFAM1 0.7992 | CACNB3 0.7536 | IKBKB 0.7521 | UBB 0.7504 | NCK1 0.7460 | UBE2N 0.7395 | THY1 0.6002 | PRKD2 0.5986 | HLA-DRB4 | P01737 | P04436 | TCRA | TCRB | TRAC | TRBC1 | TRBV12-3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of T cell activation (boxplot) | 158 | 171 | 3.0587575714590787 | 0.0011112846338918736 | 0.025364187251773158 | 0.004672897196261682 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | HES1 3.7965 | CAV1 3.7656 | FYN 3.7055 | GRB2 3.5564 | AP3B1 3.4690 | ADK 3.4277 | MAP3K7 3.1402 | CARD11 3.1018 | SOCS5 3.0169 | ITPKB 2.8294 | CD83 2.8181 | SIRPG 2.8011 | IL2RA 2.7760 | PNP 2.7166 | HLA-DMB 2.6120 | EBI3 2.6084 | KLRK1 2.5472 | HSPH1 2.4546 | YES1 2.4165 | HLA-DQA1 2.3613 | DPP4 2.3359 | GLI3 2.3270 | CCR7 2.3166 | NKAP 2.2960 | IL15 2.2242 | PDCD1LG2 2.1876 | VNN1 2.1790 | IGFBP2 2.1613 | IKZF1 2.1588 | CD28 2.1569 | HLA-DRB1 2.1516 | CD276 2.1515 | TNFSF13B 2.1364 | CD3D 2.1205 | CD3E 2.1205 | CD3G | SYK 2.1149 | AKT1 2.1144 | PTPN11 2.0897 | AIF1 2.0797 | TNFSF14 2.0782 | CD4 2.0421 | CD274 2.0243 | ZP4 2.0211 | PIK3R3 2.0057 | IGF2 1.9742 | CD80 1.9711 | CD86 1.9313 | SART1 1.9142 | RAC1 1.9125 | IL1B 1.8813 | JAK3 1.8666 | HLX 1.8571 | IL12RB1 1.8501 | PIK3R1 1.8351 | HLA-DRB5 1.8305 | BLM 1.8278 | CCL5 1.8122 | PRKCZ 1.7929 | IL12A 1.7919 | ZP3 1.7758 | MAPKAP1 1.7541 | MTOR 1.7516 | HLA-DQB1 1.7437 | MYB 1.7428 | GRAP2 1.7178 | IL6 1.7153 | VCAM1 1.7110 | PAK2 1.7086 | TNFSF11 1.7065 | IL18 1.7039 | IL6ST 1.6793 | BAD 1.6791 | IL4 1.6202 | IGF1 1.6014 | LYN 1.5986 | TGFBR2 1.5967 | HSPD1 1.5925 | SRC 1.5906 | HLA-DOB 1.5897 | CD1D 1.5801 | GATA3 1.5648 | MLST8 1.5439 | PDCD1 1.5356 | HLA-DQA2 1.5353 | HLA-DQB2 | FOXP3 1.5343 | ADAM8 1.5178 | HLA-G 1.5161 | PRKCQ 1.5129 | STAT5A 1.5114 | IL23R 1.4973 | HLA-DPA1 1.4883 | HLA-DPB1 | GIMAP5 1.4739 | RIPK2 1.4586 | NCK2 1.4470 | TNFRSF14 1.4456 | GPAM 1.4378 | ADA 1.4333 | PDPK1 1.4292 | DNAJA3 1.4206 | PTPRC 1.4182 | MAP3K8 1.4023 | VAV1 1.3902 | ZAP70 1.3847 | ITGAL 1.3652 | LILRB2 1.3636 | GLI2 1.3606 | TNFRSF13C 1.3592 | MALT1 1.3374 | PIK3CA 1.3325 | LCK 1.3129 | HLA-DRA 1.2787 | IL2 1.2715 | CD247 1.2624 | RICTOR 1.2609 | CCL19 1.2605 | CCL21 | NCKAP1L 1.2593 | PIK3R2 1.2583 | HLA-DRB3 1.2503 | SHH 1.2438 | SPN 1.2252 | ICOS 1.2215 | ICOSLG 1.2062 | XCL1 1.1948 | CCR2 1.1711 | PTPN6 1.1681 | CD5 1.1624 | PAK1 1.1424 | SASH3 1.1258 | IHH 1.1219 | IL7R 1.1090 | TRAF6 1.1053 | CDC42 1.0907 | CSK 1.0827 | TRAF2 1.0448 | CTLA4 1.0433 | IL7 1.0414 | CD74 1.0390 | RARA 1.0131 | STAT5B 1.0063 | EFNB1 0.9761 | CORO1A 0.9727 | TNFSF4 0.9088 | IFNG 0.8931 | CD47 0.8677 | BCL10 0.8189 | BTLA 0.7850 | BMI1 0.7687 | LILRB1 0.7574 | IL12B 0.7568 | NCK1 0.7460 | IL23A 0.7358 | NOD2 0.6871 | CCL2 0.6763 | IL21 0.6433 | MAP3K14 0.6324 | THY1 0.6002 | CD24 | HLA-DRB4 | P01737 | P04436 | TCRA | TCRB | TRAC | TRBC1 | TRBV12-3 | ||||||||||||||||||||||||||||||||||||
regulation of peptidyl-lysine acetylation (boxplot) | 28 | 28 | 3.05751094686197 | 0.0011159174471082611 | 0.025364187251773158 | 0.004651162790697674 | SIRT1 7.4176 | PAXIP1 3.1608 | SNAI2 2.6919 | PPARGC1A 2.4496 | SET 2.3111 | NOS1 2.3035 | CTCF 2.2550 | NOC2L 2.1228 | TWIST1 2.0979 | SNCA 1.9846 | SPI1 1.9461 | CTBP1 1.9311 | IL1B 1.8813 | MAPK3 1.8628 | MYOCD 1.8480 | MUC1 1.8194 | BRCA1 1.7066 | RPS6KA4 1.6294 | ARRB1 1.5906 | RPS6KA5 1.5702 | FOXP3 1.5343 | EID1 1.4286 | BRD7 1.3186 | TAF7 1.2741 | TGFB1 0.9693 | CHEK1 0.8631 | SOX4 0.8314 | GATA2 0.4907 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of lipase activity (boxplot) | 104 | 107 | 3.056510899250161 | 0.0011196466958824924 | 0.025364187251773158 | 0.004629629629629629 | BICD1 4.2108 | ANGPTL4 3.7320 | MAGI2 3.4637 | PLA2R1 3.4416 | APOC3 3.0248 | PRKACB 2.9293 | LMF1 2.8542 | LPAR2 2.8343 | EGFR 2.8090 | FGFR2 2.7650 | AKAP6 2.7555 | PRKCE 2.7354 | FLT1 2.6297 | APOA4 2.5911 | APOA5 2.5911 | ADCY5 2.5811 | ABHD5 2.5629 | TXK 2.5595 | ADCY2 2.5386 | CAMK4 2.5094 | ADCYAP1R1 2.5080 | DLC1 2.2963 | AGT 2.2659 | POR 2.2319 | AGTR2 2.2307 | MASTL 2.2056 | PDE1C 2.1963 | ARHGAP6 2.1854 | PRKCA 2.1719 | ADCY3 2.1650 | ADRA1A 2.1619 | ITPR2 2.1594 | PRKAR1B 2.1387 | AVPR1B 2.0938 | NTRK1 2.0462 | NGF 2.0438 | GPIHBP1 2.0087 | SNCA 1.9846 | PRKCG 1.9540 | AGTR1 1.9300 | GNA15 1.8776 | S1PR4 | LRP1 1.8683 | PLCB2 1.8631 | LPAR1 1.8285 | CCL5 1.8122 | PPT1 1.7921 | PRKAR2B 1.7791 | ITPR3 1.7657 | PRKACG 1.7616 | GNAQ 1.7558 | ADCY9 1.7405 | ADCY1 1.7392 | ADCY8 1.7139 | TIPRL 1.6773 | ANG 1.6605 | CYR61 1.6494 | PDGFRA 1.6489 | GNA13 1.6039 | FGFR1 1.5730 | PDE1A 1.5160 | RASGRP4 1.4810 | FGFR3 1.4587 | ADCY4 1.4548 | ITPR1 1.4342 | ADCY7 1.4224 | MS4A2 1.4184 | ANGPTL3 1.4147 | KIT 1.4147 | JAK2 1.4043 | PRKAR1A 1.3889 | FKBP1A 1.3770 | APOC1 1.3441 | APOC2 | NR1H3 1.3265 | FKBP1B 1.3101 | PRKAR2A 1.3064 | NCKAP1L 1.2593 | APOH 1.2376 | PDGFRB 1.2307 | VRK3 1.1979 | PDE1B 1.1847 | SELE 1.1773 | PLCG1 1.1759 | NR1H2 1.1632 | CALCR 1.1467 | SORT1 1.1418 | FGF2 1.1278 | CALM2 1.1102 | ITK 1.0826 | NMUR2 1.0684 | ADRBK1 1.0662 | PRKCD 1.0164 | GPR55 0.9634 | RGS2 0.9397 | APOA2 0.8951 | EDNRA 0.8058 | NMUR1 0.7701 | ADCY6 0.7536 | ARL1 0.7344 | PRKACA 0.6979 | AVPR1A 0.6808 | C5AR1 0.6545 | PPP2R4 0.6040 | CREB1 0.5390 | PLA2G1B 0.4953 | LA16c-360B4.1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stereocilium bundle (boxplot) | 24 | 25 | 3.0526486053685824 | 0.0011341569338758628 | 0.025419682472098467 | 0.004608294930875576 | MYO1C 4.9972 | PCDH15 3.5572 | MPP1 3.2590 | CDH23 2.9737 | KNCN 2.5329 | DOCK4 2.3990 | USH2A 2.0822 | TWF2 2.0553 | LOXHD1 2.0404 | PROM1 1.9541 | FSCN2 1.9056 | GRXCR1 1.8854 | TPRN 1.7859 | MYO7A 1.7012 | IDO1 1.6590 | CLIC5 1.6546 | TRPA1 1.5544 | KPTN 1.4933 | SLC4A7 1.4843 | ESPN 1.4330 | USH1C 1.4192 | RDX 1.1316 | MYO15A 0.7632 | STRC 0.4507 | WHRN | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
actin filament bundle (boxplot) | 47 | 47 | 3.0518974583229026 | 0.0011369988478631132 | 0.025419682472098467 | 0.0045871559633027525 | MYO1C 4.9972 | SEPT7 4.3221 | MYLK 3.2871 | SEPT11 3.2438 | SYNPO 2.9309 | NEBL 2.7784 | ZYX 2.5465 | SEPT9 2.5051 | TPM3 2.4781 | PDLIM2 2.3613 | FHOD1 2.2999 | DLC1 2.2963 | MYH11 2.2753 | AMOT 2.2199 | LIMA1 2.0815 | ACTN1 2.0386 | GAS2L2 1.9360 | ENAH 1.8839 | TEK 1.8630 | SEPT12 1.8144 | MYH6 1.8142 | MYH7 1.8142 | VIL1 1.7405 | MYL9 1.7057 | PGM5 1.7013 | FSCN1 1.6954 | SORBS1 1.6523 | GAS2L1 1.6509 | TPM1 1.5971 | MYL12B 1.5886 | MYH10 1.4980 | FERMT2 1.4965 | DAAM1 1.4884 | ACTN4 1.4437 | PDLIM7 1.3736 | SH2B2 1.3733 | TPM4 1.3177 | CNN2 1.2907 | MST1R 1.2550 | MYH9 1.1496 | ILK 1.1347 | FHL3 0.9837 | ACTA1 0.9736 | SHROOM4 0.9493 | FBLIM1 0.5285 | CRYAB 0.5155 | MICALL2 0.4408 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of neuron projection regeneration (boxplot) | 12 | 12 | 3.0509161122295034 | 0.001140721533337108 | 0.025419682472098467 | 0.0045662100456621 | NTRK3 4.8124 | SCARF1 3.2573 | TNR 3.0413 | XYLT1 2.9735 | RTN4 2.3237 | SPP1 2.1654 | EPHA4 1.6721 | NDEL1 1.5703 | STK24 1.4284 | KLK8 1.4015 | CNTF 0.8746 | OMG 0.7849 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of axon regeneration (boxplot) | 12 | 12 | 3.0509161122295034 | 0.001140721533337108 | 0.025419682472098467 | 0.0045662100456621 | NTRK3 4.8124 | SCARF1 3.2573 | TNR 3.0413 | XYLT1 2.9735 | RTN4 2.3237 | SPP1 2.1654 | EPHA4 1.6721 | NDEL1 1.5703 | STK24 1.4284 | KLK8 1.4015 | CNTF 0.8746 | OMG 0.7849 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of nucleotide metabolic process (boxplot) | 66 | 67 | 3.045992225083869 | 0.0011595691600654323 | 0.02552096809044911 | 0.004524886877828055 | ABCA1 5.6064 | ADORA3 4.1949 | ARHGEF10 3.8915 | GHRH 3.4507 | GNAL 3.0690 | PID1 2.9916 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | GUCY1A3 2.4867 | MC1R 2.3626 | ADORA2B 2.3294 | GLP1R 2.2306 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | ADCYAP1 1.8068 | FZD2 1.8049 | CAP1 1.7921 | LHCGR 1.7607 | ADM 1.7485 | MTNR1A 1.7179 | RAF1 1.7090 | GHRHR 1.6541 | ADRB1 1.6047 | P2RY11 1.5469 | ADNP 1.5371 | NPPC 1.5320 | INSL3 1.5247 | DRD1 1.4777 | RAMP1 1.4694 | APOE 1.4398 | ADCY7 1.4224 | MRAP 1.4047 | WNT5A 1.3655 | CRHR1 1.3545 | MC5R 1.3486 | NPR1 1.3340 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | CALCR 1.1467 | MC4R 1.1026 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | HCTR-6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of purine nucleotide metabolic process (boxplot) | 66 | 67 | 3.045992225083869 | 0.0011595691600654323 | 0.02552096809044911 | 0.004524886877828055 | ABCA1 5.6064 | ADORA3 4.1949 | ARHGEF10 3.8915 | GHRH 3.4507 | GNAL 3.0690 | PID1 2.9916 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | GUCY1A3 2.4867 | MC1R 2.3626 | ADORA2B 2.3294 | GLP1R 2.2306 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | ADCYAP1 1.8068 | FZD2 1.8049 | CAP1 1.7921 | LHCGR 1.7607 | ADM 1.7485 | MTNR1A 1.7179 | RAF1 1.7090 | GHRHR 1.6541 | ADRB1 1.6047 | P2RY11 1.5469 | ADNP 1.5371 | NPPC 1.5320 | INSL3 1.5247 | DRD1 1.4777 | RAMP1 1.4694 | APOE 1.4398 | ADCY7 1.4224 | MRAP 1.4047 | WNT5A 1.3655 | CRHR1 1.3545 | MC5R 1.3486 | NPR1 1.3340 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | CALCR 1.1467 | MC4R 1.1026 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | HCTR-6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of neuron projection development (boxplot) | 54 | 54 | 3.0454177729990435 | 0.0011617865233952696 | 0.02552096809044911 | 0.004484304932735426 | DCC 5.1066 | NTRK3 4.8124 | SCARF1 3.2573 | FES 3.1088 | CAMK1 2.9695 | NTRK2 2.7766 | EPHA3 2.7107 | ATF1 2.6336 | FIG4 2.6156 | CAMK1D 2.4333 | NPTN 2.3588 | BCL11A 2.3352 | CAMK2B 2.2519 | RELN 2.2249 | LTK 2.0786 | TWF2 2.0553 | NTRK1 2.0462 | PRKD1 1.9823 | KATNB1 1.9703 | RET 1.9319 | PLK5 1.8190 | ABL2 1.7537 | DPYSL3 1.7243 | UBE2V2 1.7203 | PTK7 1.6724 | LRP8 1.6538 | SERPINE2 1.6272 | VLDLR 1.6091 | CNR1 1.6061 | MARK2 1.6028 | LYN 1.5986 | BMP7 1.5842 | FGFR1 1.5730 | NDEL1 1.5703 | ADNP 1.5371 | LIF 1.4805 | P2RY2 1.4186 | PPP2R5B 1.3670 | WNT5A 1.3655 | NDNF 1.3563 | DVL1 1.2676 | FEZ1 1.2217 | AVIL 1.2074 | PTK6 1.1515 | MET 1.1441 | PTK2B 1.1280 | STMN2 1.1280 | ITGB1 1.1192 | INPP5E 1.0413 | HAP1 1.0381 | PRKCI 0.9445 | BMP5 0.9345 | CNTF 0.8746 | CBFA2T2 0.7972 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
synaptic vesicle (boxplot) | 103 | 103 | 3.0450620927903214 | 0.0011631613813543051 | 0.02552096809044911 | 0.004464285714285714 | VAMP1 4.1635 | PCLO 4.0360 | SYT9 3.5016 | ICA1 3.4698 | AMPH 3.4482 | ATP6V1G2-DDX39B 3.0639 | SLC18A3 2.7603 | STX1A 2.7012 | SYN2 2.6795 | SYT1 2.6792 | DMXL2 2.5794 | TRIM9 2.5012 | SLC6A17 2.4874 | SNAP91 2.4483 | SV2C 2.4442 | ATP6V0D1 2.4205 | TMEM163 2.3689 | SYNPR 2.3480 | MT3 2.3391 | BIN1 2.3168 | GRIN2B 2.2951 | SEPT5 2.2712 | CTTNBP2 2.2660 | SYTL2 2.2517 | CADM1 2.2215 | SYT12 2.2060 | SV2A 2.1873 | C16orf70 2.1433 | SLC18A2 2.0880 | SYN3 2.0801 | APBA1 2.0498 | SLC17A8 2.0171 | DTNBP1 2.0039 | RAB3C 1.9941 | SYT8 1.9767 | TH 1.9742 | GABBR1 1.9622 | SYPL1 1.9572 | CYP19A1 1.9264 | SYT17 1.9070 | SLC17A6 1.8970 | SYT4 1.8726 | VTI1A 1.8430 | SEPT6 1.7947 | PPT1 1.7921 | SLC17A7 1.7655 | TPRG1L 1.7652 | ABCC8 1.7488 | BRSK1 1.7013 | MME 1.6938 | DOC2B 1.6682 | RPH3A 1.6628 | SYNGR2 1.6532 | SLC2A8 1.6424 | OTOF 1.6397 | SLC32A1 1.6305 | SV2B 1.6279 | DRD2 1.5853 | NPY1R 1.5788 | SEMA4C 1.5761 | LRRK2 1.5730 | GIPC1 1.5412 | DOC2A 1.5395 | SYTL1 1.5004 | RAB3B 1.4934 | TRAPPC4 1.4783 | SYN1 1.4729 | RAB3A 1.4334 | SYNGR1 1.4155 | SYT11 1.4142 | DDC 1.3973 | LGI3 1.3710 | SNAPIN 1.3340 | CLN3 1.3063 | DNAJC5 1.2774 | GRIN1 1.2637 | SYT2 1.2635 | SYT7 1.2604 | SYT5 1.2326 | SYT3 1.2324 | GABRA2 1.2072 | ZNRF1 1.2006 | SVOP 1.1970 | RABAC1 1.1872 | STXBP5 1.1492 | SCAMP5 1.1254 | SLC40A1 1.1001 | MYLK2 1.0997 | VAMP2 1.0699 | MTMR2 1.0519 | SYT10 1.0421 | SYT6 1.0354 | CACFD1 1.0115 | SLC30A3 0.9730 | SYTL4 0.9559 | GRIA2 0.9514 | PEBP1 0.9211 | GAD2 0.8924 | SYP 0.8425 | SYPL2 0.7201 | SYNGR3 0.6909 | HCRT 0.5645 | SYT15 0.3848 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of lymphocyte differentiation (boxplot) | 97 | 97 | 3.041916339830664 | 0.0011753861012677724 | 0.02552096809044911 | 0.0044444444444444444 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | BTK 4.4391 | CD27 4.1635 | AP3B1 3.4690 | FAS 3.2882 | ERBB2 3.2295 | INPP5D 3.1650 | CARD11 3.1018 | CDKN2A 3.0353 | SOCS5 3.0169 | ITPKB 2.8294 | CD83 2.8181 | FLT3 2.7949 | IL2RA 2.7760 | PNP 2.7166 | CAMK4 2.5094 | IRF1 2.4722 | IL15RA 2.4319 | PRDM1 2.3377 | GLI3 2.3270 | NKAP 2.2960 | IL15 2.2242 | VNN1 2.1790 | IKZF1 2.1588 | SYK 2.1149 | ZBTB7B 2.1127 | CD80 1.9711 | GAS6 1.9676 | CD86 1.9313 | SART1 1.9142 | JAK3 1.8666 | BCL6 1.8618 | HLX 1.8571 | NDFIP1 1.8539 | RC3H1 1.8522 | IL12RB1 1.8501 | CD2 1.8423 | DTX1 1.8151 | PRKCZ 1.7929 | MYB 1.7428 | IL6 1.7153 | ID2 1.6791 | BAD 1.6791 | CLPTM1 1.6287 | INHBA 1.6220 | IL4 1.6202 | TGFBR2 1.5967 | GATA3 1.5648 | FOXP3 1.5343 | ADAM8 1.5178 | HLA-G 1.5161 | STAT5A 1.5114 | IL23R 1.4973 | GIMAP5 1.4739 | RIPK2 1.4586 | ADA 1.4333 | PTPRC 1.4182 | AXL 1.4159 | PRDX2 1.3938 | ZAP70 1.3847 | LILRB2 1.3636 | GLI2 1.3606 | LCK 1.3129 | IL27 1.3063 | NFKBID 1.2960 | SFRP1 1.2842 | IKZF3 1.2788 | IL2 1.2715 | CCL19 1.2605 | NCKAP1L 1.2593 | SHH 1.2438 | FOXJ1 1.2168 | SASH3 1.1258 | IHH 1.1219 | IL7R 1.1090 | BMP4 1.1081 | CTLA4 1.0433 | IL7 1.0414 | CD74 1.0390 | IRF4 1.0357 | RARA 1.0131 | STAT5B 1.0063 | IFNB1 0.9877 | TNFSF4 0.9088 | INHA 0.8631 | SOD1 0.8543 | SPINK5 0.8454 | ZC3H8 0.8031 | NFAM1 0.7992 | BMI1 0.7687 | IL29 0.7612 | IL12B 0.7568 | IFNA2 0.7466 | IL23A 0.7358 | IL21 0.6433 | NRARP 0.3378 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proteoglycan metabolic process (boxplot) | 53 | 55 | 3.0385506126858552 | 0.0011885958470208013 | 0.02558360928873848 | 0.004424778761061947 | CHST11 4.7693 | HS3ST4 4.0952 | SULF2 3.5216 | HS6ST1 3.0605 | XYLT1 2.9735 | SULF1 2.9550 | HS3ST3B1 2.9193 | SPOCK3 2.6847 | NDST4 2.6162 | CHST8 2.5435 | CSGALNACT1 2.5188 | ACAN 2.4524 | GAL3ST4 2.3305 | CHSY1 2.3303 | CHST9 2.2782 | HPSE 2.2717 | EXT1 2.2085 | NDST2 2.1818 | DSE 2.0810 | EXT2 1.9834 | NDST1 1.9496 | CHST13 1.8760 | CHST3 1.8576 | EGFLAM 1.8194 | BGN 1.7750 | CHST7 1.6567 | SGSH 1.6477 | IGF1 1.6014 | CHST12 1.5776 | LECT1 1.5203 | GPC1 1.4900 | B3GALT6 1.4593 | COL11A1 1.4339 | FOXL1 1.4158 | NDNF 1.3563 | EXTL3 1.3288 | COL2A1 1.3191 | SLC35D1 1.2687 | CYTL1 1.2397 | IL17F 1.2291 | IMPAD1 1.2243 | GLCE 1.2015 | HS2ST1 1.1877 | CHST14 1.1678 | SPOCK2 1.1539 | DCN 1.0126 | GAL3ST3 1.0039 | CSGALNACT2 0.9653 | MAMDC2 0.9200 | NDST3 0.9068 | EXTL2 0.8726 | B4GALT7 0.7869 | HS3ST5 0.5510 | RP5-1049G16.1 | tmplocus3 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
actinin binding (boxplot) | 16 | 16 | 3.0349644532125484 | 0.0012028201906917335 | 0.025776225665437764 | 0.004405286343612335 | MYPN 3.2513 | MAGI1 3.0941 | PTPRT 3.0314 | NRAP 2.7788 | PDLIM5 2.6326 | PKD2L1 2.5895 | TTN 2.4386 | PDLIM2 2.3613 | PKD2 1.9879 | PROM1 1.9541 | PDLIM3 1.7084 | PALLD 1.5733 | NPHS1 1.4983 | ITGB1 1.1192 | SYNPO2 0.9603 | DAG1 0.6937 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sarcomere (boxplot) | 116 | 118 | 3.0331350726728976 | 0.0012101362095968682 | 0.025819762096464183 | 0.0043859649122807015 | SCN3B 4.2468 | ALDOA 4.0025 | DMD 3.6492 | PSEN2 3.3139 | SYNE1 3.2809 | MYPN 3.2513 | TCAP 3.2295 | TNNC2 3.1678 | ANKRD1 2.9349 | ANK2 2.8691 | NEBL 2.7784 | SPTBN1 2.7693 | SMPX 2.6933 | FHL2 2.6776 | PDLIM5 2.6326 | KAT2B 2.5358 | MYOM1 2.5153 | TPM3 2.4781 | TIMP4 2.4753 | TTN 2.4386 | CAV3 2.3881 | GRIN2B 2.2951 | MYO18B 2.2179 | HOMER1 2.1943 | SCN8A 2.1612 | TRIM32 2.1399 | ANKRD23 2.0869 | NEB 2.0865 | ENO1 2.0766 | ACTN1 2.0386 | MYL7 2.0341 | TNNI3 2.0145 | TNNT1 | TNNI2 1.9767 | MYBPC3 1.9461 | JPH1 1.9422 | DNAJB6 1.9299 | OBSCN 1.9276 | JUP 1.9019 | HABP4 1.8717 | MYL3 1.8709 | SCN1A 1.8708 | SYNE2 1.8459 | TNNC1 1.8440 | SORBS2 1.8388 | HSPB1 1.8189 | MYH6 1.8142 | MYH7 1.8142 | MYOZ3 1.7996 | ANK1 1.7885 | TNNI1 1.7410 | NEXN 1.7265 | ACTN2 1.7215 | PDLIM3 1.7084 | SMTNL1 1.7062 | MYL9 1.7057 | PGM5 1.7013 | CASQ1 1.6978 | TNNT3 1.6778 | MMP2 1.6530 | ARF1 1.6315 | PSMA6 1.6096 | TPM1 1.5971 | KY 1.5930 | MYL12B 1.5886 | FLNC 1.5869 | MURC 1.5823 | CAPN3 1.5788 | PALLD 1.5733 | KRT19 1.5729 | RYR1 1.5561 | FLNB 1.5528 | MYL2 1.5502 | LMAN1 1.5355 | MYZAP 1.5274 | MYH1 1.5065 | MYH2 1.5065 | LDB3 1.4347 | SYNC 1.4296 | ANKRD2 1.4291 | PPP3CA 1.4235 | MYOZ2 1.3969 | CACNA1S 1.3954 | ATP2A1 1.3612 | MYL1 1.3574 | DES 1.3358 | DST 1.3319 | TPM4 1.3177 | IGFN1 1.3081 | MYL4 1.2440 | TNNT2 1.2243 | TPM2 1.1946 | OBSL1 1.1569 | MYH4 1.1555 | BMP10 1.1425 | PAK1 1.1424 | ARHGEF25 1.1372 | JPH2 1.1317 | ACTC1 1.1031 | MYLK2 1.0997 | GLRX3 1.0767 | PSEN1 1.0274 | CSRP3 1.0035 | SLC4A1 0.9918 | MYOT 0.9883 | FHL3 0.9837 | ACTA1 0.9736 | TRPC1 0.9629 | SYNPO2 0.9603 | ABRA 0.9240 | SRI 0.8747 | TRIM54 0.8158 | NBR1 0.7860 | CTNNB1 0.5466 | CRYAB 0.5155 | ITGB1BP2 0.2828 | AKAP4 0.2612 | HNTN1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of neuron apoptotic process (boxplot) | 145 | 147 | 3.032548559193866 | 0.0012124903896496564 | 0.025819762096464183 | 0.004366812227074236 | EGLN3 4.8828 | FURIN 3.4013 | GRIK2 3.2889 | MSH2 3.2026 | HIPK2 3.1565 | GHR 3.1211 | GCLM 3.0852 | TP63 3.0850 | TNF 3.0639 | BAX 3.0299 | GRID2 3.0003 | VEGFB 2.9601 | NTRK2 2.7766 | BARHL1 2.7381 | HRAS 2.6539 | STXBP1 2.6367 | ITGA1 2.5638 | PTPRF 2.5339 | PRDX3 2.4689 | PPARGC1A 2.4496 | KCNIP3 2.4352 | HRK 2.3983 | HMOX1 2.3654 | MT3 2.3391 | CASP3 2.3272 | SET 2.3111 | AGT 2.2659 | GCLC 2.2372 | GLP1R 2.2306 | NMNAT3 2.2030 | BCL2 2.1766 | TP73 2.1456 | RHOC 2.1005 | NR3C1 2.0926 | PARK7 2.0872 | GABRA5 2.0812 | LIG4 2.0575 | AKT1S1 2.0553 | NTRK1 2.0462 | NGF 2.0438 | ITSN1 2.0433 | MEF2C 2.0426 | CNTFR 2.0310 | HTT 2.0106 | SNCA 1.9846 | BRAF 1.9582 | PRKCG 1.9540 | FAIM2 1.9527 | TYRO3 1.9521 | TOX3 1.9500 | SNCB 1.9380 | CACNA1A 1.9305 | EGLN2 1.9184 | GPX1 1.8947 | RHOA | JUN 1.8868 | SRPK2 1.8699 | ESR1 1.8508 | NRBP2 1.8497 | TRIM2 1.8199 | CCL5 1.8122 | FASLG 1.8023 | PPT1 1.7921 | RAPSN 1.7860 | GRM4 1.7819 | LGMN 1.7282 | UBE2V2 1.7203 | IL6 1.7153 | GABRB2 1.7081 | IL18 1.7039 | EPHA7 1.6962 | PCSK6 1.6942 | BAG1 1.6759 | HIF1A 1.6618 | TGFA 1.6583 | XRCC4 1.6336 | ATM 1.6025 | WFS1 1.5881 | RASA1 1.5836 | ATP7A 1.5814 | TGFB2 1.5799 | MAP3K11 1.5775 | CASP9 1.5727 | CDK5 1.5715 | ADNP 1.5371 | ADAM8 1.5178 | XRCC2 1.5169 | FOXB1 1.5142 | AGRN 1.5051 | PCSK9 1.4808 | ASCL1 1.4512 | F2R 1.4291 | CASP2 1.4160 | AXL 1.4159 | JAK2 1.4043 | SIGMAR1 1.3875 | DLX1 1.3713 | NCF2 1.3613 | NDNF 1.3563 | CRHR1 1.3545 | TP53 1.3523 | AARS 1.3392 | UBE2M 1.3342 | CLN3 1.3063 | ADORA2A 1.3027 | AGAP2 1.2985 | CRLF1 1.2944 | NF1 1.2913 | RILPL1 1.2730 | MDK 1.2489 | KDM2B 1.2411 | CASP7 1.2327 | BCL2L11 1.2301 | BDNF 1.2240 | DHCR24 1.1981 | NAIP 1.1937 | TFAP2A 1.1936 | GDNF 1.1771 | ROCK1 1.1687 | NMNAT1 1.1643 | ILK 1.1347 | SOD2 1.1214 | CASP6 1.1051 | CLCF1 1.0800 | POU4F1 1.0505 | ERBB3 1.0409 | CITED1 1.0397 | PSEN1 1.0274 | TGFB3 1.0107 | NTF3 0.9832 | PRKCI 0.9445 | CCL3 0.9396 | CDK5R1 0.9094 | NR4A3 0.8978 | CNTF 0.8746 | SOD1 0.8543 | NQO1 0.8367 | CRH 0.8287 | UCN 0.8158 | SIX1 0.8071 | BCL2L1 0.8053 | ISL1 0.7237 | TFAP2B 0.7079 | NR4A2 0.6229 | EPO 0.4955 | SIX4 0.4859 | estrogen receptor | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of glucose transport (boxplot) | 74 | 74 | 3.0293940485534545 | 0.0012252241911798745 | 0.025915348043744013 | 0.004347826086956522 | FGF19 4.0340 | PRKAG2 3.7137 | NUP85 3.6421 | INPP5K 3.5378 | ERBB4 3.2809 | INSR 3.1624 | NUP93 3.1600 | C1QTNF2 3.0733 | TNF 3.0639 | PRKCB 2.9939 | PID1 2.9916 | NUP50 2.4721 | TPR 2.4566 | TRIB3 2.4349 | RANBP2 2.4302 | ARPP19 2.4280 | GCK 2.2586 | O3FAR1 2.2565 | AKT1 2.1144 | NUP205 2.0569 | GRB10 2.0523 | NUP98 2.0484 | NUP214 2.0327 | NUP35 1.9815 | INS 1.9742 | IRS1 1.9115 | IL1B 1.8813 | GPC3 1.8708 | NUP155 1.8446 | HK2 1.8360 | PIK3R1 1.8351 | MGEA5 1.8243 | IRS2 1.8084 | CLTCL1 1.8029 | SLC1A2 1.7777 | AKT2 1.7769 | CREBL2 1.7565 | NUP88 1.7108 | NUP188 1.6870 | SORBS1 1.6523 | NUPL2 1.6325 | NUP210 1.6052 | IGF1 1.6014 | NUP54 1.5513 | NUP153 1.5486 | NUP37 1.4613 | GIP 1.4524 | NUPL1 1.4297 | NUP160 1.4278 | SELS 1.4224 | ADIPOQ 1.3289 | FGF21 1.2670 | PTH 1.2270 | RPS6KB1 1.2260 | GCKR 1.2247 | GSK3A 1.2130 | NUP62 1.1930 | ENPP1 1.1901 | AAAS 1.1523 | RHOQ 1.1486 | MET 1.1441 | APPL1 1.1065 | ERBB3 1.0409 | CLIP3 0.9895 | CAPN10 0.9884 | NUP133 0.9736 | PRKCI 0.9445 | PEA15 0.8963 | SEH1L 0.8411 | ITLN1 0.8094 | RAE1 0.7112 | POM121 0.6925 | NUP43 0.5441 | NUP107 0.5235 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
glycerol ether biosynthetic process (boxplot) | 51 | 51 | 3.0222601461147076 | 0.0012544741346114385 | 0.02641965785220469 | 0.004329004329004329 | LPIN2 5.2136 | FAR2 3.4933 | LPCAT1 3.0227 | ELOVL6 2.9754 | GPD1 2.7351 | ACLY 2.7017 | AGPAT4 2.5633 | GPAT2 2.5064 | ELOVL2 2.4805 | MOGAT3 2.4686 | PCK1 2.3007 | ACSL1 2.2283 | LCLAT1 2.1535 | LPIN1 2.1486 | ELOVL1 2.0817 | ACSL5 2.0627 | AGPAT6 2.0214 | AGPAT2 2.0126 | PLCE1 2.0072 | LPL 1.9485 | ELOVL7 1.9273 | MOGAT1 1.9020 | AGPS 1.8230 | SLC25A1 1.8029 | AGPAT3 1.7230 | GK 1.7138 | DGAT1 1.7111 | PEX7 1.6864 | ACSL6 1.6845 | ANG 1.6605 | AGPAT5 1.6333 | PNPLA3 1.6241 | ACSL3 1.6086 | CDS2 1.6034 | AGPAT1 1.5913 | HSD17B12 1.5489 | FAR1 1.5101 | TECR 1.5086 | GPAM 1.4378 | DGAT2 1.4198 | ACSL4 1.2837 | GNPAT 1.2058 | FASN 1.1849 | ELOVL4 1.1167 | GPD1L 1.0398 | CDS1 1.0042 | MOGAT2 0.9999 | ELOVL5 0.8407 | ACACA 0.8142 | AGPAT9 0.6685 | ELOVL3 0.6419 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
kidney development (boxplot) | 176 | 179 | 3.0103084738483603 | 0.00130491242568187 | 0.02736395756172368 | 0.004310344827586207 | AQP2 4.0312 | HES1 3.7965 | NIPBL 3.6793 | SULF2 3.5216 | MAGI2 3.4637 | TIPARP 3.3907 | PCSK5 3.2644 | DLL1 3.2607 | PKHD1 3.2472 | ARID5B 3.1718 | ACTA2 3.1316 | ZBTB16 3.0880 | VEGFA 3.0488 | ASS1 3.0221 | ROBO2 3.0085 | ADAMTS1 2.9721 | SULF1 2.9550 | PODXL 2.9223 | PROX1 2.8868 | SOX8 2.8542 | KIF26B 2.8387 | ODC1 2.8365 | BASP1 2.7554 | PRKX 2.6609 | MYO1E 2.5057 | SOX9 2.4914 | IQCJ-SCHIP1 2.4652 | SERPINF1 2.4022 | SCHIP1 2.3967 | ACAT1 2.3578 | INVS 2.3332 | GLI3 2.3270 | SLC12A1 2.3097 | AGT 2.2659 | FGF1 2.2613 | COL4A3 2.2501 | FSTL3 2.2464 | FOXD3 2.2443 | AGTR2 2.2307 | WNT11 2.1927 | NPHS2 2.1857 | HMGCS2 2.1809 | BCL2 2.1766 | STAT1 2.1689 | LRP4 2.1606 | BAG6 2.1586 | TP73 2.1456 | PECAM1 2.1136 | PTCH1 2.1082 | ALDH1A2 2.0957 | ACVR2B 2.0747 | EYA1 2.0489 | WNT9B 2.0446 | NID1 2.0430 | MEF2C 2.0426 | VANGL2 2.0307 | PLCE1 2.0072 | PKD2 1.9879 | HNF1B 1.9806 | PROM1 1.9541 | ITGA8 1.9537 | RET 1.9319 | AGTR1 1.9300 | BMP6 1.8906 | GPC3 1.8708 | TEK 1.8630 | WNT7B 1.8583 | UPK3A 1.8418 | PAX2 1.8357 | SMO 1.8103 | FGF8 1.7956 | PTPRO 1.7894 | LEF1 1.7470 | WWTR1 1.7412 | OSR2 1.6982 | MME 1.6938 | ID2 1.6791 | PYGO1 1.6713 | GREM1 1.6695 | COL4A4 1.6590 | PDGFRA 1.6489 | NKX3-1 1.6263 | HNF1A 1.6105 | SOX11 1.6081 | SMAD4 1.6061 | TSHZ3 1.5963 | ALDH9A1 1.5934 | WFS1 1.5881 | BMP7 1.5842 | ARL3 1.5835 | SIX2 1.5825 | LRRK2 1.5730 | GATA3 1.5648 | JAG1 1.5613 | STRA6 1.5142 | APC 1.5096 | NPHS1 1.4983 | LAMB2 1.4979 | ZNF354A 1.4877 | PCSK9 1.4808 | WT1 1.4801 | HES5 1.4456 | ANGPT2 1.4272 | CALB1 1.4175 | FOXC2 1.4158 | SMAD1 1.3854 | RDH10 1.3839 | RPGRIP1L 1.3825 | GLI2 1.3606 | OVOL1 1.3428 | C1GALT1 1.3390 | TSC1 1.3322 | ADIPOQ 1.3289 | HAS2 1.3278 | MTSS1 1.3065 | NOTCH3 1.2976 | PYGO2 1.2933 | NF1 1.2913 | IRX3 1.2900 | IQGAP1 1.2792 | KLHL3 1.2450 | SHH 1.2438 | PDGFRB 1.2307 | BCL2L11 1.2301 | HEYL 1.2247 | FOXC1 1.2136 | LHX1 1.2133 | POU3F3 1.1996 | UMOD 1.1937 | TFAP2A 1.1936 | ALDH1A3 1.1799 | GDNF 1.1771 | FOXS1 1.1734 | SALL1 1.1703 | KCNJ8 1.1442 | ANGPT1 1.1416 | GDF11 1.1226 | TGFBR1 1.1193 | BMP4 1.1081 | ENPEP 1.0886 | TET2 1.0774 | TCF21 1.0756 | REN 1.0696 | APH1A 1.0646 | WNT6 1.0632 | JMJD6 1.0466 | CITED1 1.0397 | SPRY1 1.0270 | PDGFB 1.0240 | DCN 1.0126 | CTSH 0.9922 | AHI1 0.9870 | WNT4 0.9772 | OSR1 0.9759 | ID3 0.9709 | LGR4 0.9329 | AQP11 0.9209 | FOXD1 0.9206 | CD34 0.9161 | PTCD2 0.9115 | PKD1 0.8841 | RRM2B 0.8716 | SOX4 0.8314 | SGPL1 0.8268 | MPV17 0.8158 | SIX1 0.8071 | ACE 0.7753 | TFAP2B 0.7079 | FGF10 0.7055 | PAX8 0.6248 | CTNNB1 0.5466 | EGR1 0.5440 | SIX4 0.4859 | CEP290 0.3855 | CA2 0.3746 | HYAL2 0.2244 | CD24 | RALDH2 | RP5-1049G16.1 | ||||||||||||||||||||||||||||
negative regulation of astrocyte differentiation (boxplot) | 11 | 11 | 3.009751633142359 | 0.0013073069876571308 | 0.02736395756172368 | 0.004291845493562232 | NTRK3 4.8124 | DAB1 2.9720 | NR2E1 2.8955 | DLL3 2.7304 | F2 2.6432 | HMGA2 2.5708 | HES5 1.4456 | NF1 1.2913 | ATF5 1.1930 | ID4 1.1089 | NOG 0.6617 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stem cell maintenance (boxplot) | 65 | 65 | 3.0089108763523504 | 0.001310930076126482 | 0.02736395756172368 | 0.004273504273504274 | NANOG 4.0636 | PRDM16 3.9381 | HES1 3.7965 | DLL1 3.2607 | KLF10 2.9931 | LEO1 2.9167 | NR2E1 2.8955 | PROX1 2.8868 | LIN28A 2.7927 | SMARCA4 2.7826 | TBX3 2.6289 | HMGA2 2.5708 | SOX9 2.4914 | RTF1 2.4578 | BMPR1A 2.4359 | TCF7L1 2.3158 | PCM1 2.2454 | YAP1 2.1864 | SKI 2.1799 | LRP5 2.1685 | FZD7 2.1227 | TCF7L2 2.0892 | VPS72 2.0835 | WNT7A 2.0616 | LIG4 2.0575 | VANGL2 2.0307 | NANOS2 2.0091 | FGF4 2.0087 | PIWIL2 1.9058 | CTR9 1.8327 | LDB2 1.7774 | CREBBP 1.7131 | NOTCH1 1.6712 | NODAL 1.6471 | IGF1 1.6014 | TET1 1.5815 | FGFR1 1.5730 | POU5F1 1.5671 | JAG1 1.5613 | APC 1.5096 | TPT1 1.4838 | LIF 1.4805 | DICER1 1.4798 | HES5 1.4456 | ESRRB 1.4432 | ZNF358 1.4312 | KIT 1.4147 | NOTCH2 1.3830 | SFRP1 1.2842 | CDX2 1.2782 | ZCCHC11 1.2651 | RIF1 1.2458 | KLF4 1.0448 | EOMES 1.0250 | HOOK3 0.9990 | SRRT 0.9463 | SOX4 0.8314 | CDC73 0.7682 | FGF10 0.7055 | ASCL2 0.6923 | NOG 0.6617 | TFAP2C 0.6547 | SOX2 0.5800 | GATA2 0.4907 | KAT6A 0.3584 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
protein C-terminus binding (boxplot) | 159 | 160 | 3.0083996430263897 | 0.001313137628572325 | 0.02736395756172368 | 0.00425531914893617 | SIRT1 7.4176 | MYO1C 4.9972 | RBFOX1 3.7096 | NIPBL 3.6793 | SNTG1 3.5587 | AMPH 3.4482 | ERCC6 3.3262 | ERBB2 3.2295 | MSH2 3.2026 | FBLN5 3.1469 | SHANK1 3.1256 | MAGI1 3.0941 | CEP135 3.0939 | MIF4GD 2.9870 | SREBF2 2.9595 | FOXN3 2.9010 | ATP2B2 2.8342 | DGKZ 2.8053 | BAIAP2 2.7979 | SDCBP2 2.6851 | HRAS 2.6539 | CALCOCO1 2.6272 | XRCC6 2.5915 | BLOC1S2 2.5680 | STIP1 2.5557 | TNNI3K 2.5391 | FIGN 2.5084 | SPTBN5 2.4987 | CENPF 2.4744 | PRDX3 2.4689 | KCNIP3 2.4352 | CAV3 2.3881 | SHANK2 2.3841 | IGFALS 2.3782 | TAX1BP3 2.3388 | PEX16 2.3164 | GRIP1 2.2692 | CADM1 2.2215 | AP2A1 2.2056 | IFT46 2.2035 | PDZD3 2.1882 | DYNLL1 2.1532 | NSF 2.0876 | ATXN1 2.0856 | CDC20 2.0817 | LIG4 2.0575 | ARL6IP5 2.0565 | MPDZ 2.0535 | ERCC2 2.0521 | SHANK3 2.0446 | BAIAP3 2.0183 | UBE2I | COIL 2.0137 | AXIN1 1.9756 | CTBP1 1.9311 | HPCAL4 1.9097 | ERCC1 1.9069 | MID1IP1 1.8925 | TBL1X 1.8800 | CEP120 1.8629 | DLG1 1.8617 | PEX1 1.8571 | CACNA1B 1.8481 | PIK3R1 1.8351 | XRCC5 1.7960 | KPNA3 1.7574 | SNX17 1.7419 | SYNJ2BP 1.7375 | DLG4 1.7370 | NPAT 1.7011 | ATP2A2 1.6834 | ITGB3BP 1.6635 | PIAS3 1.6400 | XRCC4 1.6336 | PEX10 1.6201 | GOPC 1.6059 | ERCC3 1.6004 | MED12 1.5936 | MKI67 1.5781 | MRE11A 1.5735 | IFT52 1.5182 | DAB2 1.4589 | ERCC4 1.4444 | ABL1 1.4403 | RAB3A 1.4334 | PLEKHB1 1.4331 | PEX12 1.4265 | RAD51 1.4197 | USP7 1.4191 | DLG3 1.3998 | PICK1 1.3992 | PEX5 1.3972 | SAE1 1.3739 | PROP1 1.3707 | NCF2 1.3613 | NEFL 1.3454 | TCF4 1.3428 | DST 1.3319 | OPTN 1.3300 | SP1 1.3143 | LCK 1.3129 | PPM1A 1.3037 | HSPG2 1.2964 | MDC1 1.2721 | SIAH1 1.2389 | AKAP7 1.2143 | CIITA 1.1925 | RABAC1 1.1872 | NCL 1.1705 | MCHR1 1.1656 | HOMER3 1.1653 | KCNJ11 1.1557 | ATXN2 1.1522 | VPS4B 1.1509 | HIC2 1.1228 | SARNP 1.1226 | PFKM 1.1142 | HESX1 1.1065 | VPS4A 1.0975 | PXK 1.0895 | CSK 1.0827 | MAPRE1 1.0809 | SLC9A3R2 1.0731 | PPP2CB 1.0588 | YEATS4 1.0570 | SDC1 1.0557 | YWHAB 1.0405 | MLLT4 1.0402 | CITED1 1.0397 | PRKCD 1.0164 | TOPBP1 1.0094 | EFHC1 0.9925 | SLC4A1 0.9918 | CORO1A 0.9727 | MAPK14 0.9700 | PRRC2C 0.9663 | TAF13 0.9131 | TERF2 0.8944 | PEX26 0.8740 | SDCBP 0.8733 | ECM1 0.8686 | SCAF4 0.8543 | HSPB7 0.8485 | PABPC1 0.8422 | BCL10 0.8189 | CDK7 0.8067 | TRIM3 0.8022 | PDZD11 0.7983 | PEX6 0.7589 | CEP250 0.7451 | PCGF1 0.7068 | PPP2CA 0.6512 | TOP2A 0.6497 | TOP2B 0.6174 | SYNJ1 0.6101 | NEIL1 0.6005 | VIM 0.5553 | CTNNB1 0.5466 | GPR34 0.3195 | KCNK3 0.3093 | |||||||||||||||||||||||||||||||||||||||||||||||
response to X-ray (boxplot) | 21 | 21 | 3.0044142422657747 | 0.0013304638074522757 | 0.027428886764606832 | 0.00423728813559322 | NIPBL 3.6793 | ERCC6 3.3262 | MSH2 3.2026 | TP63 3.0850 | BRCC3 3.0641 | LRP2 2.5159 | TP73 2.1456 | LIG4 2.0575 | IKBIP 1.9902 | CCND1 1.9690 | BLM 1.8278 | ANXA1 1.8032 | ERCC8 1.7197 | XRCC4 1.6336 | THBD 1.5375 | XRCC2 1.5169 | TP53 1.3523 | SFRP1 1.2842 | BRCA2 1.2712 | XRRA1 0.8931 | SFRP2 0.7657 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cellular response to vitamin (boxplot) | 58 | 59 | 2.999864918845424 | 0.0013504968121460514 | 0.02772490514346894 | 0.004219409282700422 | ABCA1 5.6064 | NTRK3 4.8124 | RXRB 4.6854 | EPHA3 2.7107 | FZD10 2.6723 | WNT9A 2.5288 | SOX9 2.4914 | IRF1 2.4722 | FZD1 2.4363 | VDR 2.3912 | SLC6A4 2.2725 | IL15 2.2242 | WNT11 2.1927 | FZD7 2.1227 | ALDH1A2 2.0957 | WNT3 2.0876 | LTK 2.0786 | TWF2 2.0553 | WNT9B 2.0446 | WNT10B 2.0180 | GAS6 1.9676 | RET 1.9319 | TBX1 1.8661 | WNT7B 1.8583 | PAX2 1.8357 | CCL5 1.8122 | KRT13 1.8072 | FZD2 1.8049 | ADNP2 1.7998 | CYP26B1 1.7548 | ABL2 1.7537 | AQP1 1.7153 | STRA8 1.6857 | PTK7 1.6724 | WNT3A 1.6407 | WNT5B 1.6264 | LYN 1.5986 | CYP24A1 1.5931 | WNT2 1.5764 | COL1A1 1.4835 | LEP 1.4143 | MLL5 1.3929 | WNT5A 1.3655 | SFRP1 1.2842 | CYP26A1 1.1740 | PTK6 1.1515 | PTK2B 1.1280 | ITGB1 1.1192 | WNT6 1.0632 | RARA 1.0131 | OSR1 0.9759 | WNT8B 0.9546 | BGLAP 0.7645 | ZNF35 0.7454 | FZD4 0.7448 | OGT 0.6705 | LTC4S 0.5920 | SNW1 0.5348 | RALDH2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of stress-activated MAPK cascade (boxplot) | 131 | 134 | 2.999140636152479 | 0.0013537115151067702 | 0.02772490514346894 | 0.004201680672268907 | MECOM 4.3913 | CD27 4.1635 | FGF19 4.0340 | TAOK2 3.3686 | MAP2K2 3.3627 | ERCC6 3.3262 | GRIK2 3.2889 | MAP3K5 3.1884 | HIPK2 3.1565 | MAP3K7 3.1402 | MAP2K7 3.0946 | TNF 3.0639 | RAP2A 3.0635 | MAP4K5 2.9285 | TLR6 2.8628 | FZD10 2.6723 | HRAS 2.6539 | EPHB1 2.6334 | PLCB1 2.6151 | TLR9 2.5867 | IGF1R 2.4090 | SERPINF2 2.4022 | TAOK1 2.3462 | EDN1 2.3459 | CCR7 2.3166 | MAPK8IP1 2.3164 | NCOR1 2.1739 | TP73 2.1456 | GAB1 2.1327 | FZD7 2.1227 | SYK 2.1149 | AKT1 2.1144 | MEN1 2.0976 | SH3RF1 2.0775 | RIPK1 2.0686 | FGD4 2.0673 | WNT7A 2.0616 | AXIN1 1.9756 | MYC 1.9575 | MAPK1 1.9571 | BIRC7 1.9322 | IL1B 1.8813 | MAPK3 1.8628 | MAPK8IP2 1.8627 | WNT7B 1.8583 | PPEF2 1.8557 | DUSP22 1.8282 | DAXX 1.8243 | ZMYND11 1.8152 | MYD88 1.7773 | AKT2 1.7769 | MAPK8IP3 1.7605 | COPS5 1.7528 | GSTP1 1.7474 | HIPK3 1.7433 | TNFSF11 1.7065 | AMBP 1.6978 | MAP3K4 1.6850 | EPHA4 1.6721 | GREM1 1.6695 | MAP3K10 1.6660 | MAP4K2 1.6645 | MAP3K9 1.6641 | MDFI 1.6601 | TIRAP 1.6414 | F2RL1 1.6183 | MAP3K2 1.6004 | CBS 1.6003 | TGFB2 1.5799 | MAP3K11 1.5775 | SEMA4C 1.5761 | GPS2 1.5730 | SPAG9 1.5583 | MUL1 1.5551 | PKN1 1.5412 | MAP2K1 1.5376 | MAP3K6 1.5004 | DAB2IP 1.4910 | IL1A 1.4740 | MINK1 1.4611 | RIPK2 1.4586 | MID1 1.4471 | SFRP4 1.4173 | IL26 1.3942 | LTBR 1.3929 | DUSP3 1.3729 | WNT5A 1.3655 | MDFIC 1.3332 | TRAF4 1.3222 | DUSP10 1.3025 | HDAC3 1.2916 | FLT4 1.2760 | DVL2 1.2681 | CCL19 1.2605 | CCL21 | TPD52L1 1.2547 | FOXM1 1.2401 | TAOK3 1.2239 | TNFRSF11A 1.2162 | ZEB2 1.2160 | PDCD4 1.2095 | ZNF675 1.1570 | FKTN 1.1433 | PAK1 1.1424 | PTK2B 1.1280 | CARD9 1.1237 | MAP4K4 1.1155 | TRAF6 1.1053 | IRAK1 1.0945 | CDC42 1.0907 | FCER1A 1.0656 | TRAF2 1.0448 | TLR3 1.0443 | PTPLAD1 1.0192 | NOD1 1.0056 | TLR4 0.9855 | CTGF 0.9616 | IGBP1 0.8895 | DUSP19 0.8851 | SDCBP 0.8733 | DBNL 0.8579 | EDA2R 0.8420 | FOXO1 0.8294 | MAP4K1 0.8117 | NBR1 0.7860 | DVL3 0.7715 | DIXDC1 0.6947 | NOD2 0.6871 | ZNF622 0.6376 | ITCH 0.6286 | AIDA 0.6262 | WNT16 0.6218 | MLK4 | MLTK | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lipid transport (boxplot) | 148 | 153 | 2.998493031920506 | 0.0013565918027375057 | 0.02772490514346894 | 0.0041841004184100415 | ABCA1 5.6064 | ATP9A 3.8389 | CAV1 3.7656 | ATP11A 3.7283 | PRKAG2 3.7137 | SOAT1 3.1809 | OSBP2 3.1687 | APOA1 3.0248 | APOC3 | SPNS1 2.8728 | APOL2 2.7531 | PITPNA 2.6811 | SCARB1 2.6205 | APOA4 2.5911 | APOA5 2.5911 | OSBPL1A 2.5615 | OSBPL2 2.5237 | SORL1 2.4985 | SLC27A6 2.4755 | OSBPL6 2.4610 | NPC1L1 2.4288 | ACACB 2.4178 | BDKRB2 2.4033 | OSBP 2.3947 | OSBPL8 2.3928 | PLA2G5 2.3447 | PLA2G4A 2.3298 | OSBPL7 2.3205 | APOL1 2.2821 | RBP4 2.2565 | PSAP 2.2453 | ABCA12 2.2331 | ACSL1 2.2283 | COL4A3BP 2.2085 | ATP10D 2.2069 | ATP10A 2.1905 | ABCG4 2.1882 | SLC27A5 2.1872 | LCAT 2.1598 | APOM 2.1586 | SLCO2A1 2.1406 | OSBPL3 2.1038 | LRP6 2.0780 | ABCG1 2.0741 | ACSL5 2.0627 | PLA2G4F 2.0368 | GPIHBP1 2.0087 | SLC27A4 1.9556 | APOL4 1.9491 | DRD3 1.9435 | LDLR 1.9157 | ABCA4 1.9148 | APOLD1 1.8825 | CPT1B 1.8780 | PRKAA2 1.8703 | P2RX7 1.8574 | DRD4 1.8319 | ANXA1 1.8032 | OSBPL10 1.8013 | PLA2G10 1.7764 | ATP9B 1.7613 | SPNS3 1.7608 | LHCGR 1.7607 | CFHR4 1.7519 | PLTP 1.7340 | NPC2 1.7277 | KISS1R 1.7173 | GLTP 1.7122 | PPARG 1.6692 | STARD5 1.6612 | APOD 1.6583 | OSBPL11 1.6550 | SLC27A2 1.6261 | INHBA 1.6220 | CETP 1.6214 | HNF1A 1.6105 | VLDLR 1.6091 | STARD4 1.6060 | LIPC 1.6053 | ATP10B 1.5905 | DRD2 1.5853 | LRP10 1.5699 | PPARD 1.5657 | GULP1 1.5464 | APOL6 1.5397 | OSBPL5 1.5351 | CPT2 1.5335 | APOL5 1.5325 | KCNN4 1.5095 | SPNS2 1.4984 | ABCG5 1.4958 | ABCG8 1.4958 | CD36 1.4667 | HDLBP 1.4658 | CLN8 1.4407 | APOE 1.4398 | LDLRAP1 1.4279 | LBP 1.3981 | SIGMAR1 1.3875 | ATP8B1 1.3825 | CFTR 1.3770 | PLIN2 1.3717 | SCP2 1.3496 | APOC1 1.3441 | APOC2 | APOC4 | LPA 1.3392 | SLC27A1 1.3359 | LIPG 1.3223 | APOBR 1.3063 | ATP11B 1.2915 | ABCA7 1.2907 | CHKA 1.2791 | GOT2 1.2785 | MSR1 1.2705 | ATP8A1 1.2627 | CLU 1.2550 | APOB 1.2451 | APOH 1.2376 | MTTP 1.2284 | ABCA5 1.2038 | PCTP 1.1922 | CPT1A 1.1834 | VPS4B 1.1509 | CEL 1.1461 | PRKAB2 1.0760 | PNLIP 1.0731 | NMUR2 1.0684 | AKR1C1 1.0665 | PPARA 1.0266 | ATP8B3 0.9821 | SERPINA5 0.9719 | NPC1 0.9459 | ARV1 0.9451 | STARD6 0.9323 | APOA2 0.8951 | CROT 0.8342 | SOAT2 0.7990 | APOO 0.7820 | APOL3 0.7791 | ACE 0.7753 | SFTPA1 0.7503 | FZD4 0.7448 | APOF 0.7358 | SLC25A20 0.7171 | SLC25A17 0.6778 | STX12 0.6580 | OSBPL9 0.6068 | ATP11C 0.5439 | ABCD1 0.5027 | PLA2G1B 0.4953 | ADFP | FFR | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of stress-activated protein kinase signaling cascade (boxplot) | 132 | 135 | 2.9924619270197272 | 0.0013836859135825108 | 0.028052653003170735 | 0.004166666666666667 | MECOM 4.3913 | CD27 4.1635 | FGF19 4.0340 | TAOK2 3.3686 | MAP2K2 3.3627 | ERCC6 3.3262 | GRIK2 3.2889 | MAP3K5 3.1884 | HIPK2 3.1565 | MAP3K7 3.1402 | MAP2K7 3.0946 | TNF 3.0639 | RAP2A 3.0635 | MAP4K5 2.9285 | TLR6 2.8628 | FZD10 2.6723 | HRAS 2.6539 | EPHB1 2.6334 | PLCB1 2.6151 | TLR9 2.5867 | IGF1R 2.4090 | SERPINF2 2.4022 | TAOK1 2.3462 | EDN1 2.3459 | CCR7 2.3166 | MAPK8IP1 2.3164 | NCOR1 2.1739 | TP73 2.1456 | GAB1 2.1327 | FZD7 2.1227 | SYK 2.1149 | AKT1 2.1144 | MEN1 2.0976 | SH3RF1 2.0775 | RIPK1 2.0686 | FGD4 2.0673 | WNT7A 2.0616 | AXIN1 1.9756 | MYC 1.9575 | MAPK1 1.9571 | BIRC7 1.9322 | IL1B 1.8813 | MAPK3 1.8628 | MAPK8IP2 1.8627 | WNT7B 1.8583 | PPEF2 1.8557 | DUSP22 1.8282 | DAXX 1.8243 | ZMYND11 1.8152 | MYD88 1.7773 | AKT2 1.7769 | MAPK8IP3 1.7605 | COPS5 1.7528 | GSTP1 1.7474 | HIPK3 1.7433 | TNFSF11 1.7065 | AMBP 1.6978 | MAP3K4 1.6850 | EPHA4 1.6721 | GREM1 1.6695 | MAP3K10 1.6660 | MAP4K2 1.6645 | MAP3K9 1.6641 | MDFI 1.6601 | TIRAP 1.6414 | F2RL1 1.6183 | MAP3K2 1.6004 | CBS 1.6003 | LYN 1.5986 | TGFB2 1.5799 | MAP3K11 1.5775 | SEMA4C 1.5761 | GPS2 1.5730 | SPAG9 1.5583 | MUL1 1.5551 | PKN1 1.5412 | MAP2K1 1.5376 | MAP3K6 1.5004 | DAB2IP 1.4910 | IL1A 1.4740 | MINK1 1.4611 | RIPK2 1.4586 | MID1 1.4471 | SFRP4 1.4173 | IL26 1.3942 | LTBR 1.3929 | DUSP3 1.3729 | WNT5A 1.3655 | MDFIC 1.3332 | TRAF4 1.3222 | DUSP10 1.3025 | HDAC3 1.2916 | FLT4 1.2760 | DVL2 1.2681 | CCL19 1.2605 | CCL21 | TPD52L1 1.2547 | FOXM1 1.2401 | TAOK3 1.2239 | TNFRSF11A 1.2162 | ZEB2 1.2160 | PDCD4 1.2095 | ZNF675 1.1570 | FKTN 1.1433 | PAK1 1.1424 | PTK2B 1.1280 | CARD9 1.1237 | MAP4K4 1.1155 | TRAF6 1.1053 | IRAK1 1.0945 | CDC42 1.0907 | FCER1A 1.0656 | TRAF2 1.0448 | TLR3 1.0443 | PTPLAD1 1.0192 | NOD1 1.0056 | TLR4 0.9855 | CTGF 0.9616 | IGBP1 0.8895 | DUSP19 0.8851 | SDCBP 0.8733 | DBNL 0.8579 | EDA2R 0.8420 | FOXO1 0.8294 | MAP4K1 0.8117 | NBR1 0.7860 | DVL3 0.7715 | DIXDC1 0.6947 | NOD2 0.6871 | ZNF622 0.6376 | ITCH 0.6286 | AIDA 0.6262 | WNT16 0.6218 | MLK4 | MLTK | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
negative regulation of lipase activity (boxplot) | 10 | 10 | 2.9856811405618613 | 0.0014147375255284533 | 0.028563667560876128 | 0.004149377593360996 | BICD1 4.2108 | ANGPTL4 3.7320 | PLA2R1 3.4416 | APOC3 3.0248 | POR 2.2319 | ANGPTL3 1.4147 | APOC1 1.3441 | SORT1 1.1418 | RGS2 0.9397 | APOA2 0.8951 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
contractile fiber (boxplot) | 150 | 152 | 2.9763706503474916 | 0.0014584104913896168 | 0.02932425374868176 | 0.004132231404958678 | SCN3B 4.2468 | ALDOA 4.0025 | DMD 3.6492 | PSEN2 3.3139 | SYNE1 3.2809 | MYPN 3.2513 | TCAP 3.2295 | TNNC2 3.1678 | ACTA2 3.1316 | ANKRD1 2.9349 | ANK2 2.8691 | NEBL 2.7784 | SPTBN1 2.7693 | SMPX 2.6933 | FHL2 2.6776 | ABLIM2 2.6700 | PDLIM5 2.6326 | KAT2B 2.5358 | MYOM1 2.5153 | TPM3 2.4781 | TIMP4 2.4753 | TTN 2.4386 | CAV3 2.3881 | GRIN2B 2.2951 | MYH11 2.2753 | CALD1 2.2528 | MYO18B 2.2179 | HOMER1 2.1943 | SCN8A 2.1612 | TRIM32 2.1399 | CST3 2.1381 | ACTB 2.1337 | MYBPC1 2.0903 | ANKRD23 2.0869 | NEB 2.0865 | ENO1 2.0766 | TWF2 2.0553 | NPNT 2.0460 | ACTN1 2.0386 | MYL7 2.0341 | LRRC10 2.0175 | TNNI3 2.0145 | TNNT1 | PDE4DIP 1.9973 | TNNI2 1.9767 | TWF1 1.9582 | PPP1R12A 1.9556 | MYL6B 1.9522 | MYBPC3 1.9461 | JPH1 1.9422 | DNAJB6 1.9299 | OBSCN 1.9276 | ACTG1 1.9056 | JUP 1.9019 | HABP4 1.8717 | MYL3 1.8709 | SCN1A 1.8708 | SYNE2 1.8459 | TNNC1 1.8440 | SORBS2 1.8388 | HSPB1 1.8189 | MYH6 1.8142 | MYH7 1.8142 | MYOZ3 1.7996 | ANK1 1.7885 | TMOD1 1.7664 | TNNI1 1.7410 | NEXN 1.7265 | ACTN2 1.7215 | VCL 1.7125 | PDLIM3 1.7084 | SMTNL1 1.7062 | MYL9 1.7057 | PGM5 1.7013 | MYH15 1.7006 | CASQ1 1.6978 | TNNT3 1.6778 | IDO1 1.6590 | MMP2 1.6530 | ARF1 1.6315 | FXR1 1.6121 | PSMA6 1.6096 | TPM1 1.5971 | KY 1.5930 | MYL12B 1.5886 | FLNC 1.5869 | MURC 1.5823 | CAPN3 1.5788 | PALLD 1.5733 | KRT19 1.5729 | RYR1 1.5561 | FLNB 1.5528 | MYL2 1.5502 | LMAN1 1.5355 | MYZAP 1.5274 | MYH1 1.5065 | MYH2 1.5065 | LDB3 1.4347 | SYNC 1.4296 | ANKRD2 1.4291 | PPP3CA 1.4235 | SVIL 1.3995 | MYOZ2 1.3969 | CACNA1S 1.3954 | ATP2A1 1.3612 | MYL1 1.3574 | DES 1.3358 | DST 1.3319 | PLEC 1.3309 | TPM4 1.3177 | IGFN1 1.3081 | SDC4 1.2900 | MYOD1 1.2690 | MYL4 1.2440 | TNNT2 1.2243 | TPM2 1.1946 | OBSL1 1.1569 | MYH13 1.1562 | MYH4 1.1555 | MYH8 1.1555 | KCNJ8 1.1442 | BMP10 1.1425 | PAK1 1.1424 | ARHGEF25 1.1372 | ILK 1.1347 | JPH2 1.1317 | ACTC1 1.1031 | MYLK2 1.0997 | GLRX3 1.0767 | SYNM 1.0740 | MYH3 1.0276 | PSEN1 1.0274 | CSRP3 1.0035 | SLC4A1 0.9918 | MYOT 0.9883 | FHL3 0.9837 | ACTA1 0.9736 | TRPC1 0.9629 | SYNPO2 0.9603 | ABRA 0.9240 | CDK5R1 0.9094 | SRI 0.8747 | TRIM54 0.8158 | NBR1 0.7860 | DAG1 0.6937 | MYL5 0.6911 | CTNNB1 0.5466 | CRYAB 0.5155 | MYLPF 0.4455 | ITGB1BP2 0.2828 | AKAP4 0.2612 | HNTN1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
extracellular ligand-gated ion channel activity (boxplot) | 71 | 74 | 2.9659828233607106 | 0.001508586699796588 | 0.030208830390189054 | 0.00823045267489712 | GRID1 5.7829 | GRIK4 3.9399 | GABRG3 3.6968 | GRIA4 3.3765 | GRIK2 3.2889 | GRIN3A 3.1467 | GRID2 3.0003 | GABRB3 2.9924 | HTR3B 2.8560 | GABRR3 2.6005 | GLRA2 2.5894 | GABRA3 2.4286 | GRIA3 2.4068 | HTR3E 2.3683 | HTR3C 2.3466 | P2RX5 2.3388 | CHRNB1 2.2963 | GRIN2B 2.2951 | GABRG1 2.2106 | GRIN2A 2.0931 | GABRA5 2.0812 | CHRNA10 2.0484 | HTR3D 2.0080 | GRIK3 2.0041 | GABRQ 1.9995 | GRIN2C 1.9757 | P2RX1 1.9501 | P2RX7 1.8574 | CHRNA2 1.8484 | GRIK1 1.8243 | GABRG2 1.8133 | GRIK5 1.7636 | CHRND 1.7516 | GABRR1 1.7119 | GABRB2 1.7081 | CHRNA7 1.6719 | GABRB1 1.6717 | GLRA3 1.6714 | ZACN 1.5950 | GABRA1 1.5731 | CHRNA9 1.5108 | P2RX4 1.5095 | CHRNG 1.4825 | CHRNE 1.4611 | GLRA1 1.4443 | P2RX3 1.3783 | GRIN2D 1.3766 | CHRNA1 1.3109 | GABRD 1.2730 | GRIN1 1.2637 | GABRP 1.2409 | GABRA2 1.2072 | GLRA4 1.2033 | CHRNA4 1.2001 | CHRNA3 1.1921 | CHRNB4 | GLRB 1.1896 | HTR3A 1.1787 | GABRE 1.1782 | CHRNA5 1.1534 | GRIA1 1.1475 | GRIN3B 1.0627 | GRIA2 0.9514 | CHRNB2 0.9425 | GABRR2 0.8946 | GABRA6 0.8703 | P2RX6 0.7959 | GABRA4 0.7578 | P2RX2 0.6514 | STX1B 0.5451 | CHRNA6 0.3958 | CHRNB3 0.3372 | CHRFAM7A | CHRNA7-2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stem cell development (boxplot) | 70 | 70 | 2.9623356448494023 | 0.0015265738016394526 | 0.03044424324412394 | 0.00819672131147541 | NANOG 4.0636 | PRDM16 3.9381 | HES1 3.7965 | DLL1 3.2607 | MSI2 3.0206 | KLF10 2.9931 | LEO1 2.9167 | NR2E1 2.8955 | PROX1 2.8868 | LIN28A 2.7927 | SMARCA4 2.7826 | TBX3 2.6289 | HMGA2 2.5708 | SOX9 2.4914 | RTF1 2.4578 | BMPR1A 2.4359 | TCF7L1 2.3158 | PCM1 2.2454 | YAP1 2.1864 | SKI 2.1799 | LRP5 2.1685 | FZD7 2.1227 | TCF7L2 2.0892 | VPS72 2.0835 | WNT7A 2.0616 | LIG4 2.0575 | VANGL2 2.0307 | NANOS2 2.0091 | FGF4 2.0087 | PIWIL2 1.9058 | CTR9 1.8327 | LDB2 1.7774 | CREBBP 1.7131 | NOTCH1 1.6712 | NODAL 1.6471 | IGF1 1.6014 | TET1 1.5815 | FGFR1 1.5730 | POU5F1 1.5671 | JAG1 1.5613 | APC 1.5096 | TPT1 1.4838 | LIF 1.4805 | DICER1 1.4798 | HES5 1.4456 | ESRRB 1.4432 | ZNF358 1.4312 | PTPRC 1.4182 | KIT 1.4147 | NOTCH2 1.3830 | SETD2 1.3663 | SFRP1 1.2842 | CDX2 1.2782 | ZCCHC11 1.2651 | RIF1 1.2458 | SHH 1.2438 | FGF2 1.1278 | KLF4 1.0448 | EOMES 1.0250 | HOOK3 0.9990 | SRRT 0.9463 | SOX4 0.8314 | CDC73 0.7682 | FGF10 0.7055 | ASCL2 0.6923 | NOG 0.6617 | TFAP2C 0.6547 | SOX2 0.5800 | GATA2 0.4907 | KAT6A 0.3584 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
response to calcium ion (boxplot) | 90 | 90 | 2.958928615563231 | 0.0015435530163327993 | 0.030657723730902673 | 0.00816326530612245 | AQP2 4.0312 | CAV1 3.7656 | AANAT 3.6243 | KCNMA1 3.3055 | RYR2 3.1737 | KCNIP1 2.8571 | AQP3 2.7086 | SYT1 2.6792 | KCNMB2 2.6357 | RYR3 2.5711 | APOBEC1 2.5650 | ENTPD6 2.5066 | STIM1 2.4544 | TTN 2.4386 | KCNMB3 2.4149 | VDR 2.3912 | SPARC 2.3530 | PLA2G4A 2.3298 | GRIN2B 2.2951 | SCN5A 2.2668 | PDE1C 2.1963 | HOMER1 2.1943 | ALOX5AP 2.1705 | PCSK1 2.1639 | ACTB 2.1337 | GRIN2A 2.0931 | MEF2C 2.0426 | HTT 2.0106 | TSHB 2.0094 | DUSP1 2.0029 | NEDD4 1.9836 | CCND1 1.9690 | KCNMB4 1.9400 | ASPH 1.9379 | HTR2B 1.9303 | MGP 1.9249 | SEC31A 1.9219 | ACTG1 1.9056 | JUN 1.8868 | P2RX7 1.8574 | FOSB 1.8474 | KCNIP2 1.8243 | NEUROD2 1.8013 | CLIC4 1.7778 | D2HGDH 1.7728 | ITPR3 1.7657 | IL6 1.7153 | JUND 1.6861 | AKR1C3 1.6264 | JUNB 1.6024 | CAPN3 1.5788 | PDCD6 1.5772 | KRT10 1.5517 | ALG2 1.5481 | FOS 1.5019 | EP300 1.4888 | MEF2A 1.4880 | PEF1 1.4724 | SLC6A1 1.4647 | SLC25A13 1.4619 | WNT5A 1.3655 | CACYBP 1.3633 | DPEP1 1.3546 | TRPC3 1.3214 | ADAM9 1.3137 | TPH2 1.3056 | S100A16 1.3048 | FGB 1.2648 | MTTP 1.2284 | TNNT2 1.2243 | CASR 1.2002 | FGA 1.1804 | PTK2B 1.1280 | CALM2 1.1102 | CRHBP 1.0855 | GPLD1 1.0747 | KCNMB1 1.0743 | SLC25A12 1.0694 | NPPB 1.0642 | SDC1 1.0557 | GIPR 1.0312 | TRPC1 0.9629 | PEBP1 0.9211 | MNAT1 0.9174 | ANXA11 0.8916 | FGG 0.8458 | LCE1D 0.8445 | THBS1 0.7292 | ECT2 0.5904 | TXNIP 0.5187 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of stress fiber assembly (boxplot) | 37 | 38 | 2.957504962968478 | 0.0015506987817582862 | 0.030674956468303594 | 0.008130081300813009 | ARHGEF10 3.8915 | ARAP1 3.7330 | INPP5K 3.5378 | NF2 3.2554 | SYNPO 2.9309 | EPHA1 2.5465 | TACSTD2 2.4154 | SERPINF2 2.4022 | SORBS3 2.3613 | FHOD1 2.2999 | DLC1 2.2963 | AMOT 2.2199 | WNT11 2.1927 | ARHGAP6 2.1854 | SMAD3 2.1433 | ROCK2 2.0790 | RHOA 1.8947 | MTOR 1.7516 | KISS1R 1.7173 | TAC1 1.6069 | TPM1 1.5971 | PTGER4 1.5596 | PRKCQ 1.5129 | ARHGEF10L 1.4113 | BAG4 1.3675 | TACR1 1.3533 | TSC1 1.3322 | SDC4 1.2900 | ARHGEF15 1.2884 | SFRP1 1.2842 | PPM1F 1.1863 | ROCK1 1.1687 | PAK1 1.1424 | S1PR1 1.0347 | CTGF 0.9616 | GPR65 0.8893 | PPM1E 0.7885 | FRAP1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (boxplot) | 19 | 24 | 2.9545406097258535 | 0.0015656746946066669 | 0.030846316765516833 | 0.008097165991902834 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | MARCH1 2.7144 | CTSE 2.6897 | HLA-DMB 2.6120 | HLA-DQA1 2.3613 | HLA-DRB1 2.1516 | HLA-DRB5 1.8305 | HLA-DQB1 1.7437 | MARCH8 1.7406 | HLA-DOB 1.5897 | TAP2 1.5897 | HLA-DQA2 1.5353 | HLA-DQB2 | HLA-DPA1 1.4883 | HLA-DPB1 | HLA-DRA 1.2787 | IFI30 1.2584 | HLA-DRB3 1.2503 | CD74 1.0390 | FCER1G 0.8951 | E7ENX8 | F6UB75 | HLA-DRB4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
DNA biosynthetic process (boxplot) | 15 | 15 | 2.951329417974322 | 0.001582046318650665 | 0.03104368800372349 | 0.008064516129032258 | SIRT1 7.4176 | POLA1 6.3131 | REV1 1.6804 | DTL 1.6627 | POLH 1.6146 | PCNA 1.6034 | RFC3 1.6016 | REV3L 1.5246 | KIAA2022 1.3027 | POLD3 1.2925 | WRN 1.2667 | POLD1 1.1632 | WRNIP1 1.0872 | POLE 1.0804 | CDKN2D 0.9929 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
insulin receptor signaling pathway (boxplot) | 145 | 147 | 2.950293641754965 | 0.0015873602071461157 | 0.03104368800372349 | 0.008032128514056224 | ATP6V1D 5.0589 | CRK 4.9972 | FGF19 4.0340 | PRKAG2 3.7137 | GRB2 3.5564 | EIF4G1 3.5399 | MAP2K2 3.3627 | INSR 3.1624 | PHIP 3.1621 | ATP6V1G2 3.0639 | BAIAP2 2.7979 | FGFR2 2.7650 | HRAS 2.6539 | RPTOR 2.5941 | TLR9 2.5867 | STXBP4 2.5613 | SIK2 2.5468 | FRS2 2.5419 | FGF7 2.5131 | TRIB3 2.4349 | ATP6V0D1 2.4205 | IGF1R 2.4090 | FGF17 2.4040 | ATP6V1C1 2.3669 | IDE 2.3580 | FGF1 2.2613 | FGF23 2.2484 | FGF22 2.2464 | ATP6V1B1 2.1332 | GAB1 2.1327 | CAB39L 2.1178 | AKT1 2.1144 | PTPN11 2.0897 | FOXO3 2.0675 | GRB10 2.0523 | EIF4B 2.0361 | PTPRA 2.0157 | FGF4 2.0087 | PIK3R3 2.0057 | ATP6V0D2 1.9877 | ATP6V0A2 1.9809 | IGF2 1.9742 | INS | MAPK1 1.9571 | IRS1 1.9115 | FER 1.8987 | FGF9 1.8959 | ATP6V1G1 1.8891 | PRKAA2 1.8703 | MAPK3 1.8628 | SREBF1 1.8466 | PIK3R1 1.8351 | IRS2 1.8084 | FGF8 1.7956 | ATP6V0A1 1.7946 | FOXO4 1.7940 | PTPN2 1.7929 | AKT2 1.7769 | ATP6V0E2 1.7632 | MTOR 1.7516 | SHC2 1.7321 | EIF4EBP2 1.7274 | KL 1.7172 | RAF1 1.7090 | PDE3B 1.7081 | FGF18 1.7053 | ATP6V1E1 1.6865 | SORBS1 1.6523 | ATP6V0A4 1.6520 | SMARCC1 1.6448 | SLC2A8 1.6424 | ZFP106 1.6400 | ATP6V1C2 1.6347 | BCAR1 1.6063 | FGF5 1.6008 | EIF4EBP1 1.6002 | EEF2K 1.5954 | ATP6V1F 1.5869 | FGF3 1.5781 | FGFR1 1.5730 | MLST8 1.5439 | MAP2K1 1.5376 | CAB39 1.5334 | ATP6V1H 1.5286 | ATP6V1E2 1.5221 | TCIRG1 1.5133 | FGFR3 1.4587 | ATP6V1B2 1.4506 | GRB14 1.4400 | ATP6V0B 1.4365 | SHC3 1.4335 | PDPK1 1.4292 | PTPN1 1.4205 | FOXC2 1.4158 | THEM4 1.3903 | SH2B2 1.3733 | KLB 1.3538 | ATP6V0E1 1.3495 | PIK3CA 1.3325 | TSC1 1.3322 | NR1H3 1.3265 | AP3S1 1.3252 | PPM1A 1.3037 | SHC1 1.2933 | PIK3R2 1.2583 | FGF20 1.2458 | CDK1 1.2389 | RPS6KB1 1.2260 | GSK3A 1.2130 | STRADB 1.1749 | FOXS1 1.1734 | STK11 1.1724 | SOS1 1.1496 | RHOQ 1.1486 | FGFR4 1.1354 | ATP6V0C 1.1317 | FGF2 1.1278 | PRKAG1 1.1069 | APPL1 1.1065 | PRKAB2 1.0760 | GPLD1 1.0747 | TSC2 1.0731 | PRKAG3 1.0632 | ATP6V1A 1.0601 | YWHAB 1.0405 | PIK3R4 1.0348 | PRKAB1 1.0322 | FGF16 1.0317 | IGFBP1 0.9990 | KRAS 0.9975 | FGF6 0.9927 | RHEB 0.9858 | SOCS7 0.9852 | DOK1 0.9629 | STRADA 0.9421 | NRAS 0.9279 | PIK3CB 0.9249 | PIK3C2A 0.8669 | FOXO1 0.8294 | NAMPT 0.8179 | EIF4E 0.7883 | PRKAA1 0.7726 | PIK3C3 0.7608 | FGF10 0.7055 | ATP6V1G3 0.6241 | RPS6 0.3423 | FOXO6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
glutamate receptor signaling pathway (boxplot) | 26 | 26 | 2.9484347732652125 | 0.0015969376554862968 | 0.031086204719944405 | 0.008 | GRIK4 3.9399 | GRIA4 3.3765 | GRIK2 3.2889 | GRID2 3.0003 | PLCB1 2.6151 | GRIA3 2.4068 | HOMER2 2.3096 | GRIN2B 2.2951 | HOMER1 2.1943 | APP 2.1303 | GRIN2A 2.0931 | GRIK3 2.0041 | GRM5 1.9765 | GRIN2C 1.9757 | GRIK1 1.8243 | GRM4 1.7819 | GNAQ 1.7558 | GRM6 1.5126 | CLN3 1.3063 | GRIN1 1.2637 | ATP1A3 1.1872 | HOMER3 1.1653 | GRIN3B 1.0627 | SSTR1 1.0219 | GRIA2 0.9514 | CDK5R1 0.9094 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lipid translocation (boxplot) | 14 | 14 | 2.946454096522914 | 0.0016072006250531512 | 0.03116183434130832 | 0.00796812749003984 | ABCA1 5.6064 | ATP9A 3.8389 | ATP11A 3.7283 | ATP10D 2.2069 | ATP10A 2.1905 | P2RX7 1.8574 | ATP9B 1.7613 | ATP10B 1.5905 | KCNN4 1.5095 | ATP8B1 1.3825 | ATP11B 1.2915 | ATP8A1 1.2627 | ATP8B3 0.9821 | ATP11C 0.5439 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
phospholipid translocation (boxplot) | 14 | 14 | 2.946454096522914 | 0.0016072006250531512 | 0.03116183434130832 | 0.00796812749003984 | ABCA1 5.6064 | ATP9A 3.8389 | ATP11A 3.7283 | ATP10D 2.2069 | ATP10A 2.1905 | P2RX7 1.8574 | ATP9B 1.7613 | ATP10B 1.5905 | KCNN4 1.5095 | ATP8B1 1.3825 | ATP11B 1.2915 | ATP8A1 1.2627 | ATP8B3 0.9821 | ATP11C 0.5439 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
stem cell differentiation (boxplot) | 98 | 98 | 2.942891585207666 | 0.0016258113393859963 | 0.03127446537102353 | 0.007905138339920948 | NANOG 4.0636 | PRDM16 3.9381 | HES1 3.7965 | PAX7 3.3979 | DLL1 3.2607 | MSI2 3.0206 | KLF10 2.9931 | LEO1 2.9167 | NR2E1 2.8955 | PROX1 2.8868 | LIN28A 2.7927 | SMARCA4 2.7826 | TBX3 2.6289 | SOX18 2.5964 | HMGA2 2.5708 | SOX9 2.4914 | RTF1 2.4578 | FZD1 2.4363 | BMPR1A 2.4359 | GPM6A 2.3326 | CDON 2.3231 | TCF7L1 2.3158 | PCM1 2.2454 | YAP1 2.1864 | SKI 2.1799 | LRP5 2.1685 | FZD7 2.1227 | A2M 2.1102 | TCF7L2 2.0892 | WNT3 2.0876 | VPS72 2.0835 | WNT7A 2.0616 | LIG4 2.0575 | ERCC2 2.0521 | CDK6 2.0335 | HHEX 2.0321 | VANGL2 2.0307 | NANOS2 2.0091 | FGF4 2.0087 | HNF1B 1.9806 | PIWIL2 1.9058 | MEGF10 1.8707 | PAX2 1.8357 | CTR9 1.8327 | XRCC5 1.7960 | LDB2 1.7774 | CREBBP 1.7131 | JARID2 1.7060 | NOTCH1 1.6712 | NODAL 1.6471 | IGF1 1.6014 | TET1 1.5815 | FGFR1 1.5730 | POU5F1 1.5671 | JAG1 1.5613 | APC 1.5096 | SOX21 1.5055 | TAL1 1.4925 | MSX1 1.4876 | TPT1 1.4838 | LIF 1.4805 | DICER1 1.4798 | HES5 1.4456 | ESRRB 1.4432 | ZNF358 1.4312 | PTPRC 1.4182 | KIT 1.4147 | NOTCH2 1.3830 | SETD2 1.3663 | SFRP1 1.2842 | CDX2 1.2782 | ZCCHC11 1.2651 | RIF1 1.2458 | SHH 1.2438 | SOX10 1.2019 | SRF 1.1778 | FGF2 1.1278 | MYLK2 1.0997 | MSX2 1.0645 | KLF4 1.0448 | EOMES 1.0250 | HOOK3 0.9990 | OSR1 0.9759 | SRRT 0.9463 | HOXD4 0.9055 | HOXA7 0.8607 | SOX17 0.8386 | SOX4 0.8314 | ETV4 0.8207 | ACE 0.7753 | CDC73 0.7682 | FGF10 0.7055 | ASCL2 0.6923 | NOG 0.6617 | TFAP2C 0.6547 | SOX2 0.5800 | GATA2 0.4907 | KAT6A 0.3584 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sarcolemma (boxplot) | 87 | 88 | 2.940498552823817 | 0.0016384226612866648 | 0.0313934632276339 | 0.015748031496062992 | KCNJ12 5.2371 | SCN2A 3.6519 | DMD 3.6492 | KCND3 3.5097 | CHRM4 3.3170 | KCNJ5 3.0325 | SGCG 3.0172 | PLCB3 2.9532 | SLC8A1 2.7718 | COL6A2 2.7393 | SGCZ 2.5939 | KCNQ1 2.5850 | ADCY5 2.5811 | CAMK2D 2.5615 | SLC27A6 2.4755 | VDR 2.3912 | CAV3 2.3881 | SGCD 2.3072 | NOS1 2.3035 | PLD2 2.2800 | SNTG2 2.2762 | SCN5A 2.2668 | DYSF 2.2333 | LAMA2 2.2226 | CACNB2 2.2123 | COL6A1 2.1167 | BSG 2.0858 | SLC30A1 2.0329 | DTNBP1 2.0039 | CACNA2D1 1.9982 | SNTB1 1.9473 | CTSB 1.9372 | SLC8A3 1.9072 | SGCB 1.8841 | DLG1 1.8617 | ESR1 1.8508 | COL6A3 1.8501 | ANXA1 1.8032 | BGN 1.7750 | SGCA 1.7693 | ABCC8 1.7488 | AQP1 1.7153 | VCAM1 1.7110 | PGM5 1.7013 | CASQ1 1.6978 | PEMT 1.6828 | KCNJ3 1.6361 | CAPN3 1.5788 | SLC2A4 1.5730 | KRT19 1.5729 | LAMP1 1.5580 | RYR1 1.5561 | SSPN 1.5492 | PRKCQ 1.5129 | ANXA5 1.4923 | CLCN1 1.4840 | SYNC 1.4296 | ANXA2 1.4037 | CACNA1S 1.3954 | SLMAP 1.3918 | ALOX12 1.3844 | DES 1.3358 | PLEC 1.3309 | PRKAR2A 1.3064 | AKAP7 1.2143 | CACNB1 1.1775 | KCNJ11 1.1557 | KCNJ8 1.1442 | SGCE 1.1407 | ITGB1 1.1192 | ATP1A1 1.0906 | ADRB2 1.0467 | TGFB3 1.0107 | FGF6 0.9927 | MYOT 0.9883 | ALOX5 0.9146 | CA4 0.8965 | FKRP 0.8929 | EDNRA 0.8058 | ADCY6 0.7536 | DAG1 0.6937 | STX4 0.6681 | ANXA2P2 0.6424 | SNTA1 0.5644 | ATP1A2 0.4943 | KCNJ18 0.4591 | TRIM72 0.4005 | estrogen receptor | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cellular response to vitamin A (boxplot) | 48 | 49 | 2.935861555322652 | 0.0016631136817998327 | 0.03174208378622649 | 0.01568627450980392 | ABCA1 5.6064 | NTRK3 4.8124 | RXRB 4.6854 | EPHA3 2.7107 | FZD10 2.6723 | WNT9A 2.5288 | SOX9 2.4914 | IRF1 2.4722 | SLC6A4 2.2725 | WNT11 2.1927 | FZD7 2.1227 | ALDH1A2 2.0957 | WNT3 2.0876 | LTK 2.0786 | TWF2 2.0553 | WNT9B 2.0446 | WNT10B 2.0180 | RET 1.9319 | TBX1 1.8661 | WNT7B 1.8583 | PAX2 1.8357 | KRT13 1.8072 | ADNP2 1.7998 | CYP26B1 1.7548 | ABL2 1.7537 | AQP1 1.7153 | STRA8 1.6857 | PTK7 1.6724 | WNT3A 1.6407 | WNT5B 1.6264 | LYN 1.5986 | WNT2 1.5764 | COL1A1 1.4835 | LEP 1.4143 | MLL5 1.3929 | WNT5A 1.3655 | CYP26A1 1.1740 | PTK6 1.1515 | PTK2B 1.1280 | WNT6 1.0632 | RARA 1.0131 | OSR1 0.9759 | WNT8B 0.9546 | ZNF35 0.7454 | FZD4 0.7448 | OGT 0.6705 | LTC4S 0.5920 | SNW1 0.5348 | RALDH2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
voltage-gated calcium channel activity (boxplot) | 32 | 32 | 2.9353270285020305 | 0.0016659816004057637 | 0.03174208378622649 | 0.015625 | CACNB4 3.1376 | CACNA1G 3.0242 | CACNA1C 2.8754 | GRM7 2.8268 | CACNG3 2.6709 | TPCN2 2.5016 | CACNA1H 2.4410 | CACNG4 2.2546 | CACNB2 2.2123 | CACNA1D 2.1182 | CACNA1E 2.0970 | CACNA2D1 1.9982 | PKD2 1.9879 | GAS6 1.9676 | CACNA2D3 1.9648 | CACNG7 1.9540 | CACNA1A 1.9305 | CATSPER1 1.8550 | CACNA1B 1.8481 | CACNG1 1.8336 | ITGAV 1.7509 | CACNG6 1.6930 | CACNG5 1.6745 | CACNA1I 1.6100 | RYR1 1.5561 | CACNA1S 1.3954 | CACNG2 1.3692 | CACNG8 1.2699 | CACNB1 1.1775 | FGF2 1.1278 | CACNA1F 0.9583 | CACNB3 0.7536 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
protein autophosphorylation (boxplot) | 151 | 156 | 2.9301114272363296 | 0.0016942023837165365 | 0.032084778476120145 | 0.01556420233463035 | NTRK3 4.8124 | EIF2S1 4.5714 | FYN 3.7055 | ERBB4 3.2809 | ERBB2 3.2295 | INSR 3.1624 | FES 3.1088 | ALK 2.9520 | SIK1 2.8664 | EGFR 2.8090 | MELK 2.8083 | FLT3 2.7949 | NTRK2 2.7766 | EIF2AK2 2.7737 | FGFR2 2.7650 | TRPM7 2.7626 | CSNK2A1 2.7243 | PRKX 2.6609 | EPHB1 2.6334 | FLT1 2.6297 | MUSK 2.5943 | CAMK2D 2.5615 | TXK 2.5595 | SIK2 2.5468 | EPHA1 2.5465 | TNIK 2.5237 | DAPK2 2.4457 | IGF1R 2.4090 | EIF2AK1 2.3081 | CHEK2 2.2881 | CAMK2B 2.2519 | ULK2 2.2154 | MAK 2.1724 | PASK 2.1664 | CAMK2A 2.1496 | MYO3A 2.1330 | SYK 2.1149 | AKT1 2.1144 | MAPKAPK5 2.1048 | MAP3K12 2.0825 | RIPK1 2.0686 | CLK1 2.0672 | NTRK1 2.0462 | PIM1 2.0233 | MAP3K1 1.9924 | PRKD1 1.9823 | IRAK3 1.9617 | TYRO3 1.9521 | FER 1.8987 | CAMKK2 1.8746 | JAK3 1.8666 | TEK 1.8630 | AATK 1.8455 | MAPK7 1.8453 | PEAK1 1.8398 | GRK5 1.8323 | MOB1B 1.7907 | EPHA8 1.7658 | CLK4 1.7615 | MTOR 1.7516 | INSRR 1.7414 | DAPK3 1.7213 | VRK1 1.7153 | PAK2 1.7086 | MAPK15 1.6970 | EPHA4 1.6721 | MAP3K10 1.6660 | MAP3K9 1.6641 | TAF1 1.6628 | STK4 1.6533 | PDGFRA 1.6489 | DDR1 1.6458 | TSSK2 1.6414 | DYRK1A 1.6138 | STK16 1.6097 | MARK2 1.6028 | ATM 1.6025 | LYN 1.5986 | EEF2K 1.5954 | VRK2 1.5922 | MAP3K11 1.5775 | LRRK2 1.5730 | FGFR1 1.5730 | CDK5 1.5715 | WNK2 1.5580 | KDR 1.5543 | HCK 1.4790 | MAP3K13 1.4769 | MINK1 1.4611 | FGFR3 1.4587 | SLK 1.4533 | NLK 1.4362 | PDPK1 1.4292 | STK24 1.4284 | EPHB4 1.4218 | KIT 1.4147 | JAK2 1.4043 | PTK2 1.3822 | ERN1 1.3742 | CSNK1G2 1.3418 | DAPK1 1.3354 | LCK 1.3129 | FLT4 1.2760 | TRIM28 1.2663 | BMX 1.2654 | LMTK2 1.2623 | CSF1R 1.2307 | PDGFRB 1.2307 | TAOK3 1.2239 | STK10 1.2155 | ULK3 1.2009 | DDR2 1.1922 | FGR 1.1781 | NEK2 1.1750 | STK11 1.1724 | CLK2 1.1605 | PTK6 1.1515 | MET 1.1441 | PAK1 1.1424 | AURKA 1.1367 | FGFR4 1.1354 | PTK2B 1.1280 | TGFBR1 1.1193 | MYLK2 1.0997 | STK33 1.0975 | IRAK1 1.0945 | TRIM24 1.0739 | GRK7 1.0708 | MEX3B 1.0448 | SMG1 1.0298 | CDKL5 1.0190 | AAK1 0.9958 | NEK6 0.9782 | CAD 0.9730 | MAPK14 0.9700 | WNK3 0.9692 | CDK12 0.9477 | MAP3K3 0.9421 | ULK1 0.9247 | PHKA1 0.8977 | ATR 0.8945 | AURKB 0.8722 | TNK1 0.8330 | GRK1 0.8278 | EIF2AK3 0.7800 | ACVR1B 0.7753 | UHMK1 0.7480 | PRKACA 0.6979 | EPHB3 0.6149 | PRKD2 0.5986 | CLK3 0.3891 | DKFZp686A20267 | FRAP1 | MLK4 | MNB | DYRK | |||||||||||||||||||||||||||||||||||||||||||||||||||
myofibril (boxplot) | 139 | 141 | 2.929264906884336 | 0.0016988236075027308 | 0.032084778476120145 | 0.015503875968992248 | SCN3B 4.2468 | ALDOA 4.0025 | DMD 3.6492 | PSEN2 3.3139 | SYNE1 3.2809 | MYPN 3.2513 | TCAP 3.2295 | TNNC2 3.1678 | ANKRD1 2.9349 | ANK2 2.8691 | NEBL 2.7784 | SPTBN1 2.7693 | SMPX 2.6933 | FHL2 2.6776 | ABLIM2 2.6700 | PDLIM5 2.6326 | KAT2B 2.5358 | MYOM1 2.5153 | TPM3 2.4781 | TIMP4 2.4753 | TTN 2.4386 | CAV3 2.3881 | GRIN2B 2.2951 | CALD1 2.2528 | MYO18B 2.2179 | HOMER1 2.1943 | SCN8A 2.1612 | TRIM32 2.1399 | ACTB 2.1337 | MYBPC1 2.0903 | ANKRD23 2.0869 | NEB 2.0865 | ENO1 2.0766 | TWF2 2.0553 | ACTN1 2.0386 | MYL7 2.0341 | LRRC10 2.0175 | TNNI3 2.0145 | TNNT1 | PDE4DIP 1.9973 | TNNI2 1.9767 | TWF1 1.9582 | MYBPC3 1.9461 | JPH1 1.9422 | DNAJB6 1.9299 | OBSCN 1.9276 | ACTG1 1.9056 | JUP 1.9019 | HABP4 1.8717 | MYL3 1.8709 | SCN1A 1.8708 | SYNE2 1.8459 | TNNC1 1.8440 | SORBS2 1.8388 | HSPB1 1.8189 | MYH6 1.8142 | MYH7 1.8142 | MYOZ3 1.7996 | ANK1 1.7885 | TMOD1 1.7664 | TNNI1 1.7410 | NEXN 1.7265 | ACTN2 1.7215 | VCL 1.7125 | PDLIM3 1.7084 | SMTNL1 1.7062 | MYL9 1.7057 | PGM5 1.7013 | MYH15 1.7006 | CASQ1 1.6978 | TNNT3 1.6778 | MMP2 1.6530 | ARF1 1.6315 | FXR1 1.6121 | PSMA6 1.6096 | TPM1 1.5971 | KY 1.5930 | MYL12B 1.5886 | FLNC 1.5869 | MURC 1.5823 | CAPN3 1.5788 | PALLD 1.5733 | KRT19 1.5729 | RYR1 1.5561 | FLNB 1.5528 | MYL2 1.5502 | LMAN1 1.5355 | MYZAP 1.5274 | MYH1 1.5065 | MYH2 1.5065 | LDB3 1.4347 | SYNC 1.4296 | ANKRD2 1.4291 | PPP3CA 1.4235 | SVIL 1.3995 | MYOZ2 1.3969 | CACNA1S 1.3954 | ATP2A1 1.3612 | MYL1 1.3574 | DES 1.3358 | DST 1.3319 | TPM4 1.3177 | IGFN1 1.3081 | SDC4 1.2900 | MYOD1 1.2690 | MYL4 1.2440 | TNNT2 1.2243 | TPM2 1.1946 | OBSL1 1.1569 | MYH13 1.1562 | MYH4 1.1555 | MYH8 1.1555 | KCNJ8 1.1442 | BMP10 1.1425 | PAK1 1.1424 | ARHGEF25 1.1372 | ILK 1.1347 | JPH2 1.1317 | ACTC1 1.1031 | MYLK2 1.0997 | GLRX3 1.0767 | SYNM 1.0740 | MYH3 1.0276 | PSEN1 1.0274 | CSRP3 1.0035 | SLC4A1 0.9918 | MYOT 0.9883 | FHL3 0.9837 | ACTA1 0.9736 | TRPC1 0.9629 | SYNPO2 0.9603 | ABRA 0.9240 | SRI 0.8747 | TRIM54 0.8158 | NBR1 0.7860 | DAG1 0.6937 | CTNNB1 0.5466 | CRYAB 0.5155 | ITGB1BP2 0.2828 | AKAP4 0.2612 | HNTN1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
clathrin coated vesicle membrane (boxplot) | 95 | 95 | 2.927502868260896 | 0.0017084795456370205 | 0.03210627330762493 | 0.015444015444015444 | VAMP1 4.1635 | PICALM 3.8576 | SYT9 3.5016 | ICA1 3.4698 | HIP1 3.4696 | AP3B1 3.4690 | AMPH 3.4482 | NCALD 3.4326 | ATP6V1G2-DDX39B 3.0639 | EGFR 2.8090 | SLC18A3 2.7603 | VAMP3 2.7537 | STX1A 2.7012 | SYT1 2.6792 | DMXL2 2.5794 | SLC6A17 2.4874 | SV2C 2.4442 | AP1S1 2.3948 | TMEM163 2.3689 | SYNPR 2.3480 | CD207 2.2783 | SYT12 2.2060 | AP2A1 2.2056 | SV2A 2.1873 | C16orf70 2.1433 | AP3B2 2.1374 | SLC18A2 2.0880 | SYN3 2.0801 | SLC17A8 2.0171 | DTNBP1 2.0039 | AP1M1 1.9590 | MYO6 1.9297 | AP1G1 1.9242 | LDLR 1.9157 | SLC17A6 1.8970 | SYT4 1.8726 | AP2A2 1.8451 | CLTCL1 1.8029 | SLC17A7 1.7655 | ABCC8 1.7488 | SGIP1 1.7021 | RPH3A 1.6628 | AP1B1 1.6509 | OTOF 1.6397 | SLC32A1 1.6305 | SV2B 1.6279 | DRD2 1.5853 | SEMA4C 1.5761 | DOC2A 1.5395 | SYN1 1.4729 | DAB2 1.4589 | CLTA 1.4478 | RAB3A 1.4334 | HIP1R 1.4332 | LDLRAP1 1.4279 | SYNGR1 1.4155 | SYT11 1.4142 | NECAP2 1.3674 | DENND1A 1.3576 | AP2S1 1.3442 | SNAPIN 1.3340 | AP1M2 1.2846 | HSPA8 1.2788 | DNAJC5 1.2774 | CLTC 1.2691 | TYRP1 1.2671 | EPN2 1.2666 | SYT2 1.2635 | SYT7 1.2604 | APOB 1.2451 | SYT5 1.2326 | SYT3 1.2324 | GABRA2 1.2072 | NECAP1 1.2032 | SYNRG 1.2028 | ZNRF1 1.2006 | SVOP 1.1970 | SLC18A1 1.1645 | AFTPH 1.1535 | SCAMP5 1.1254 | GAD1 1.0859 | VAMP2 1.0699 | SYT10 1.0421 | SYT6 1.0354 | CACFD1 1.0115 | SLC30A3 0.9730 | GRIA2 0.9514 | CLTB 0.9372 | FCGR1A 0.9281 | GAD2 0.8924 | RASSF9 0.8752 | SYP 0.8425 | FCGR1B 0.7513 | EPS15 0.7236 | AP1G2 0.4863 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
protein binding, bridging (boxplot) | 129 | 130 | 2.926644154302204 | 0.001713203366146665 | 0.03210627330762493 | 0.015384615384615385 | CRK 4.9972 | COL11A2 4.6854 | BICD1 4.2108 | GRB2 3.5564 | FKBP4 3.2506 | EVPL 2.9838 | ARPC4 2.9695 | ARHGAP10 2.9174 | LAT 2.8728 | BAIAP2 2.7979 | CHN2 2.7414 | COL6A2 2.7393 | STX1A 2.7012 | RBM14 2.6896 | FRS2 2.5419 | ARHGAP26 2.5226 | CRADD 2.4878 | BIN3 2.4249 | SKAP1 2.4173 | SHB 2.4114 | CLNK 2.3813 | COL19A1 2.3157 | CRKL 2.3083 | LASP1 2.3015 | SH2D3C 2.2820 | FCRL2 2.2566 | CUX1 2.2383 | GAB2 2.2298 | BLNK 2.2008 | COL14A1 2.1863 | ARHGAP6 2.1854 | CD28 2.1569 | ITSN2 2.1500 | GAB1 2.1327 | MEN1 2.0976 | GRB10 2.0523 | SH2D2A 2.0466 | SH3BP2 2.0378 | SH2D1B 2.0268 | PSMC6 1.9935 | HSH2D 1.9590 | ASAP1 1.9430 | GAS2L2 1.9360 | IRS1 1.9115 | PAG1 1.9087 | FSCN2 1.9056 | PRKAA2 1.8703 | SLA 1.8438 | VAV3 1.8406 | SORBS2 1.8388 | SH3BGR 1.8241 | ANXA1 1.8032 | ACAP3 1.8009 | GATAD2A 1.7930 | ANK1 1.7885 | ABI2 1.7385 | GRAP2 1.7178 | COL8A2 1.7125 | ADAP2 1.6995 | FLRT1 1.6980 | FSCN3 1.6957 | FSCN1 1.6954 | BAIAP2L1 1.6951 | SH3GLB2 1.6870 | SKAP2 1.6689 | SORBS1 1.6523 | GAS2L1 1.6509 | TIRAP 1.6414 | STAM 1.6170 | DOK2 1.6163 | STAP1 1.6094 | SRC 1.5906 | PPP4R2 1.5834 | CNKSR1 1.5044 | LOR 1.5031 | EPS8 1.4871 | CHN1 1.4789 | CBX5 1.4600 | ARHGAP1 1.4596 | NCK2 1.4470 | GRB14 1.4400 | NUFIP1 1.4362 | COL11A1 1.4339 | LDLRAP1 1.4279 | COL1A2 1.4123 | BAIAP2L2 1.3992 | TOB1 1.3959 | GRAP 1.3954 | SH2B2 1.3733 | SLA2 1.3387 | MTSS1 1.3065 | SHC1 1.2933 | RAD50 1.2733 | SH3GLB1 1.2730 | CNTNAP1 1.2662 | FGB 1.2648 | TNNT2 1.2243 | ARHGAP42 1.2122 | GRB7 1.1828 | GOLGA5 1.1812 | FGA 1.1804 | OBSL1 1.1569 | MMS19 1.1470 | BCL3 1.1329 | MTSS1L 1.1236 | SH2D3A 1.1155 | FLRT2 1.0677 | TP53BP2 1.0534 | STUB1 1.0527 | SH2D1A 1.0331 | DSP 1.0262 | IRS4 1.0252 | SH3BGRL 1.0131 | FLRT3 0.8901 | SDCBP 0.8733 | OPHN1 0.8605 | FGG 0.8458 | TRAT1 0.8232 | SOCS2 0.8180 | SPRR1A 0.8078 | ARHGAP4 0.7810 | NCK1 0.7460 | HSPA5 0.6930 | IVL 0.6857 | ST13 0.6778 | SPRR1B 0.6655 | RUSC1 0.5709 | KHDRBS1 0.5046 | CSTA 0.4033 | HNTN1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cell aging (boxplot) | 18 | 18 | 2.9244948747685044 | 0.0017250788060516609 | 0.032170744451787844 | 0.01532567049808429 | SIRT1 7.4176 | CDKN2A 3.0353 | ING2 2.8259 | HMGA2 2.5708 | MIF 2.1324 | TWIST1 2.0979 | PNPT1 2.0485 | CDK6 2.0335 | WNT1 2.0180 | MARCH5 1.4717 | PTEN 1.3846 | TP53 1.3523 | FOXM1 1.2401 | NUAK1 1.1328 | FZR1 1.0884 | HMGA1 1.0845 | LMNA 1.0722 | NEK6 0.9782 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
potassium ion transport (boxplot) | 95 | 97 | 2.923417784469952 | 0.001731058204920477 | 0.032170744451787844 | 0.015267175572519083 | KCNJ12 5.2371 | SLC12A8 4.6192 | KCND3 3.5097 | KCNA5 3.3453 | KCNMA1 3.3055 | KCNK10 3.2871 | KCNJ4 3.2311 | SLC12A6 3.1445 | KCNJ5 3.0325 | KCNQ4 2.8155 | KCNK9 2.7381 | KCNMB2 2.6357 | PKD2L1 2.5895 | KCNQ1 2.5850 | KCNH1 2.5742 | SLC12A5 2.5026 | KCNMB3 2.4149 | SLC12A7 2.4107 | KCNC4 2.3714 | SLC12A1 2.3097 | HCN1 2.2865 | KCNE2 2.2438 | KCNQ3 2.2037 | SLC12A4 2.1598 | NSF 2.0876 | KCNAB1 2.0747 | KCNJ6 2.0282 | KCNK18 2.0117 | PKD2 1.9879 | SLC24A4 1.9794 | KCNMB4 1.9400 | SLC24A2 1.9291 | KCNB2 1.9269 | KCNT2 1.9253 | KCNT1 1.9150 | KCNA2 1.8775 | KCNC1 1.8772 | KCNN1 1.8466 | KCNE1 1.8416 | KCNK13 1.8332 | KCNK1 1.8306 | KCNIP2 1.8243 | KCNH2 1.8168 | ABCC8 1.7488 | KCNA1 1.7305 | HPN 1.7202 | AQP1 1.7153 | ABCC9 1.7062 | ATP1A4 1.6978 | SLC24A5 1.6778 | KCNK5 1.6574 | KCNJ3 1.6361 | KCNK7 1.5775 | KCNK16 1.5155 | KCNK17 | KCNN4 1.5095 | TMEM38A 1.5051 | KCNK4 1.4691 | KCNN2 1.4571 | KCNAB3 1.4270 | KCNA6 1.4115 | KCNJ16 1.3936 | TSC1 1.3322 | KCNA10 1.3288 | KCNJ1 1.2945 | KCNG2 1.2727 | KCNQ2 1.2247 | KCNK2 1.1962 | ATP1A3 1.1872 | KCNK6 1.1799 | KCNV1 1.1761 | KCNS1 1.1656 | KCNJ11 1.1557 | CDKN1B 1.1519 | VPS4B 1.1509 | KCNJ8 1.1442 | KCNF1 1.1068 | KCNJ2 1.0875 | KCNH4 1.0789 | KCNU1 1.0750 | KCNMB1 1.0743 | KCNH3 1.0368 | KCNS3 1.0343 | KCNJ15 1.0099 | SLC12A2 0.9968 | KCNG1 0.9673 | CDK2 0.8908 | TMEM38B 0.8406 | KCNJ10 0.8338 | KCNC3 0.8056 | KCNA3 0.7220 | KCNA4 0.6180 | KCND1 0.5914 | ATP1A2 0.4943 | KCNJ13 0.4431 | KCNK3 0.3093 | CHP | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of synaptic transmission, glutamatergic (boxplot) | 13 | 13 | 2.9206783517936565 | 0.0017463510869483168 | 0.032320725041020744 | 0.015209125475285171 | NRXN1 3.6097 | GRIA4 3.3765 | TNR 3.0413 | NLGN1 2.7866 | OXTR 2.3881 | RELN 2.2249 | SHANK3 2.0446 | PTGS2 1.9806 | NLGN3 1.5936 | DRD1 1.4777 | CCKBR 1.3511 | ADORA2A 1.3027 | NLGN2 0.6604 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of smooth muscle cell apoptotic process (boxplot) | 10 | 10 | 2.9202985516110167 | 0.0017484809983707716 | 0.032320725041020744 | 0.015151515151515152 | SIRT1 7.4176 | CDKN2A 3.0353 | EDN1 2.3459 | LRP6 2.0780 | IL12A 1.7919 | IGF1 1.6014 | APOH 1.2376 | APOPT1 1.0707 | IFNG 0.8931 | IL12B 0.7568 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of ion transmembrane transporter activity (boxplot) | 92 | 92 | 2.9174067765149836 | 0.0017647756912122503 | 0.03241614295963555 | 0.01509433962264151 | NRXN1 3.6097 | CACNB4 3.1376 | SHANK1 3.1256 | EFCAB4B 2.9151 | CACNA1C 2.8754 | OPRM1 2.8228 | NLGN1 2.7866 | CACNG3 2.6709 | YWHAH 2.6079 | PKD2L1 2.5895 | CXCL12 2.5696 | CAMK2D 2.5615 | TPCN2 2.5016 | STIM1 2.4544 | PLCG2 2.4205 | SESTD1 2.4004 | VDR 2.3912 | CAV3 2.3881 | AGT 2.2659 | CACNG4 2.2546 | NKX2-5 2.2385 | GLP1R 2.2306 | RELN 2.2249 | CACNB2 2.2123 | HOMER1 2.1943 | JPH3 2.1788 | CACNA1D 2.1182 | CNIH2 2.1101 | RHOC 2.1005 | CACNA1E 2.0970 | CCKAR 2.0865 | SHANK3 2.0446 | IL1RAPL1 2.0206 | CACNA2D1 1.9982 | PKD2 1.9879 | GAS6 1.9676 | CACNG7 1.9540 | DRD3 1.9435 | JPH1 1.9422 | OPRD1 1.9420 | ASPH 1.9379 | CACNA1A 1.9305 | CNIH3 1.8983 | MAPK8IP2 1.8627 | CACNA1B 1.8481 | CACNG1 1.8336 | DRD4 1.8319 | ZP3 1.7758 | ITGAV 1.7509 | DLG4 1.7370 | CACNG6 1.6930 | CACNG5 1.6745 | NCS1 1.6216 | CACNA1I 1.6100 | ADRB1 1.6047 | NLGN3 1.5936 | DRD2 1.5853 | WNK2 1.5580 | RYR1 1.5561 | MYO5A 1.5529 | MINK1 1.4611 | STIM2 1.4476 | ACTN4 1.4437 | TRPC6 1.4311 | CACNA1S 1.3954 | FKBP1A 1.3770 | CACNG2 1.3692 | DAPK1 1.3354 | SCN1B 1.3219 | FKBP1B 1.3101 | ADORA2A 1.3027 | CACNG8 1.2699 | CACNB1 1.1775 | PLCG1 1.1759 | ADRA2A 1.1742 | JPH2 1.1317 | CALM2 1.1102 | CRHBP 1.0855 | SCN2B 1.0517 | ADRB2 1.0467 | WNK3 0.9692 | CACNA1F 0.9583 | CRH 0.8287 | TMEM66 0.8252 | RANGRF 0.7954 | CACNB3 0.7536 | AHCYL1 0.7381 | SLC9A3R1 0.7026 | NLGN2 0.6604 | GNAI2 0.5640 | EPO 0.4955 | JPH4 0.4863 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
second-messenger-mediated signaling (boxplot) | 93 | 94 | 2.9103170320699228 | 0.0018053115153793264 | 0.0330365245848067 | 0.015037593984962405 | BTK 4.4391 | PDE2A 3.7330 | GHRH 3.4507 | RYR2 3.1737 | TNF 3.0639 | LAT 2.8728 | EGFR 2.8090 | DDAH2 2.7706 | LACRT 2.7283 | CAMK2D 2.5615 | GUCY1B3 2.5107 | ADCYAP1R1 2.5080 | MAFA 2.5049 | PLA2G4B 2.4987 | FPR1 2.4962 | SOX9 2.4914 | GUCY1A3 2.4867 | PLCG2 2.4205 | PDE3A 2.3821 | EDN1 2.3459 | DDAH1 2.3427 | AGT 2.2659 | AGTR2 2.2307 | GLP1R 2.2306 | PDZD3 2.1882 | MCTP2 2.1777 | EPHA5 2.1737 | ITPR2 2.1594 | MCTP1 2.1496 | FIS1 2.0275 | PLCE1 2.0072 | HDAC4 1.9670 | CYTH3 1.9639 | HTR2B 1.9303 | AGTR1 1.9300 | EDN2 1.8797 | CAMKK2 1.8746 | RCAN1 1.8416 | ALMS1 1.8311 | HRH1 1.7853 | ITPR3 1.7657 | ADM 1.7485 | EIF4EBP2 1.7274 | KISS1R 1.7173 | ADCY8 1.7139 | CASQ1 1.6978 | RAPGEF4 1.6971 | GHRHR 1.6541 | GRM1 1.6533 | RAPGEF2 1.6242 | MCU 1.6010 | DGKD 1.5653 | KDR 1.5543 | P2RY11 1.5469 | DGKQ 1.5429 | SPHK1 1.5010 | HTR5A 1.4880 | DRD1 1.4777 | CD36 1.4667 | TREML1 1.4638 | NUDT4 1.4402 | APOE 1.4398 | ITPR1 1.4342 | PTGDR2 1.4283 | GPR143 1.4262 | TFF2 1.3753 | LAT2 1.3653 | RCAN2 1.3279 | FKBP1B 1.3101 | IL8 1.2857 | CXCR4 1.2607 | PDE7A 1.2485 | BHLHA15 1.2296 | CASR 1.2002 | SELE 1.1773 | CCR5 1.1711 | RASD1 1.1143 | EDN3 1.1118 | PDX1 1.0828 | NMUR2 1.0684 | RCAN3 0.9673 | CCL3 0.9396 | GPRC6A 0.8917 | DMPK 0.8803 | NDUFS4 0.8049 | EIF2AK3 0.7800 | NMUR1 0.7701 | PPP2R1A 0.7692 | NEUROD1 0.7493 | BCAP31 0.7171 | SLC9A3R1 0.7026 | AVPR1A 0.6808 | PPP2CA 0.6512 | DSCR1L2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of astrocyte differentiation (boxplot) | 21 | 21 | 2.909646218017076 | 0.0018091904365138411 | 0.0330365245848067 | 0.0149812734082397 | NTRK3 4.8124 | HES1 3.7965 | DAB1 2.9720 | NR2E1 2.8955 | DLL3 2.7304 | F2 2.6432 | HMGA2 2.5708 | CNTN2 2.2820 | ID2 1.6791 | EPHA4 1.6721 | NOTCH1 1.6712 | SERPINE2 1.6272 | BMP2 1.5776 | LIF 1.4805 | HES5 1.4456 | NF1 1.2913 | ATF5 1.1930 | PRPF19 1.1381 | ID4 1.1089 | CLCF1 1.0800 | NOG 0.6617 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
mitogen-activated protein kinase binding (boxplot) | 17 | 17 | 2.90879084237326 | 0.0018141475627653225 | 0.0330365245848067 | 0.014925373134328358 | SIRT1 7.4176 | TNIP1 2.8951 | NFATC1 2.1519 | DUSP2 2.1223 | MAPKAPK5 2.1048 | MICALCL 2.1009 | ATF7 2.0825 | MAP3K1 1.9924 | RPS6KA4 1.6294 | PTPRJ 1.5709 | SPAG9 1.5583 | GTF2I 1.5020 | EP300 1.4888 | ABL1 1.4403 | PLCB4 1.3630 | PEBP1 0.9211 | NBR1 0.7860 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
adipose tissue development (boxplot) | 18 | 18 | 2.9052021105535686 | 0.0018350801129679573 | 0.03320815345170903 | 0.01486988847583643 | CSF1 3.5095 | AACS 3.2912 | ARID5B 3.1718 | SOX8 2.8542 | HMGA2 2.5708 | ACAT1 2.3578 | HMGCS2 2.1809 | LRP5 2.1685 | FTO 2.1567 | BDH1 1.7405 | ATF2 1.7025 | ID2 1.6791 | PPARD 1.5657 | DGAT2 1.4198 | LEP 1.4143 | OXCT1 1.3697 | SH3PXD2B 0.9550 | NAMPT 0.8179 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
endocytic vesicle membrane (boxplot) | 73 | 76 | 2.9013269216041926 | 0.0018579299364385182 | 0.0334975854960834 | 0.014814814814814815 | VAMP1 4.1635 | PICALM 3.8576 | CAV1 3.7656 | B2M 3.6670 | GRIA4 3.3765 | RILP 3.3070 | CUBN 2.9709 | TLR1 2.8628 | TLR6 2.8628 | EGFR 2.8090 | SLC18A3 2.7603 | SYT1 2.6792 | CACNG3 2.6709 | CAMK2D 2.5615 | GRIA3 2.4068 | HLA-F 2.2828 | CD207 2.2783 | CACNG4 2.2546 | CAMK2B 2.2519 | AP2A1 2.2056 | CAMK2G 2.1818 | CALR 2.1592 | RPS27A 2.1523 | CAMK2A 2.1496 | OCRL 2.0031 | AP2B1 1.9360 | LDLR 1.9157 | ANXA3 1.9125 | RAB11FIP1 1.9080 | AP2A2 1.8451 | SLC11A1 1.7405 | DLG4 1.7370 | SGIP1 1.7021 | TAPBP 1.6801 | HLA-B 1.6543 | NOS3 1.6288 | TAP1 1.5897 | TAP2 | CYBB 1.5177 | HLA-G 1.5161 | IRGM 1.4964 | CLTA 1.4478 | LDLRAP1 1.4279 | HLA-A | DMBT1 1.4123 | PICK1 1.3992 | CACNG2 1.3692 | AP2S1 1.3442 | SEC61B 1.3364 | UBC 1.3324 | UBA52 1.2944 | HLA-E 1.2721 | CACNG8 1.2699 | TYRP1 1.2671 | EPN2 1.2666 | SYT2 1.2635 | APOB 1.2451 | SEC61G 1.2319 | NOSTRIN 1.1758 | WASL 1.1528 | GRIA1 1.1475 | HLA-C 1.1295 | INPP5B 1.1013 | SEC61A2 1.1004 | VAMP2 1.0699 | CYBA 1.0419 | CORO1A 0.9727 | GRIA2 0.9514 | FCGR1A 0.9281 | SEC61A1 0.8280 | FCGR1B 0.7513 | UBB 0.7504 | MDM2 0.7327 | EPS15 0.7236 | AP2M1 0.5064 | VAMP7 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
embryonic limb morphogenesis (boxplot) | 99 | 104 | 2.9012374752923638 | 0.001858460391968797 | 0.0334975854960834 | 0.014760147601476014 | CHST11 4.7693 | MECOM 4.3913 | SALL4 3.8389 | NIPBL 3.6793 | PSEN2 3.3139 | ZBTB16 3.0880 | TP63 3.0850 | HOXA11 2.9921 | HOXA13 | HOXA9 2.9921 | MBNL1 2.8792 | CRABP2 2.8723 | SMARCA4 2.7826 | PBX1 2.6903 | TBX3 2.6289 | WNT9A 2.5288 | BMPR1A 2.4359 | ECE1 2.4001 | GNA12 2.3370 | GLI3 2.3270 | ACD 2.2550 | AFF3 2.2363 | SKI 2.1799 | LRP5 2.1685 | LRP4 2.1606 | PTCH1 2.1082 | TWIST1 2.0979 | ALDH1A2 2.0957 | WNT3 2.0876 | LRP6 2.0780 | ALX4 2.0645 | WNT7A 2.0616 | LMBR1 2.0526 | FGF4 2.0087 | TBX5 1.9756 | TULP3 1.9626 | FGF9 1.8959 | GPC3 1.8708 | HOXD11 1.8126 | HOXD13 | HOXD9 1.8126 | RSPO2 1.8089 | MUSTN1 1.7901 | SP9 1.7865 | GNAQ 1.7558 | CYP26B1 1.7548 | LEF1 1.7470 | CREBBP 1.7131 | OSR2 1.6982 | GJA5 1.6874 | NOTCH1 1.6712 | GREM1 1.6695 | HNF1A 1.6105 | PBX2 1.5913 | BMP7 1.5842 | FGFR1 1.5730 | TBX4 1.5316 | IFT52 1.5182 | MSX1 1.4876 | DICER1 1.4798 | FLVCR1 1.4767 | FBXW4 1.4676 | MMP13 1.4661 | ZNF358 1.4312 | RDH10 1.3839 | NOTCH2 1.3830 | RPGRIP1L 1.3825 | WNT5A 1.3655 | GLI2 1.3606 | IFT122 1.3452 | PRRX1 1.2712 | SHH 1.2438 | IMPAD1 1.2243 | HAND2 1.1943 | TFAP2A 1.1936 | GNAS 1.1857 | RARG 1.1840 | SALL1 1.1703 | RAB23 1.1331 | PRRX2 1.1307 | BMP4 1.1081 | MED1 1.0961 | MSX2 1.0645 | PSEN1 1.0274 | CHD7 1.0210 | PITX1 0.9816 | OSR1 0.9759 | GAS1 0.9741 | FBN2 0.9552 | EN1 0.9522 | SP8 0.9512 | HDAC2 0.9044 | DLX6 0.8896 | IFT88 0.8853 | DLX5 0.8523 | HDAC1 0.8048 | SFRP2 0.7657 | NOG 0.6617 | KIAA1715 0.6331 | GDF5 0.6266 | CTNNB1 0.5466 | EVI1 | LNP | RALDH2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
embryonic appendage morphogenesis (boxplot) | 99 | 104 | 2.9012374752923638 | 0.001858460391968797 | 0.0334975854960834 | 0.014760147601476014 | CHST11 4.7693 | MECOM 4.3913 | SALL4 3.8389 | NIPBL 3.6793 | PSEN2 3.3139 | ZBTB16 3.0880 | TP63 3.0850 | HOXA11 2.9921 | HOXA13 | HOXA9 2.9921 | MBNL1 2.8792 | CRABP2 2.8723 | SMARCA4 2.7826 | PBX1 2.6903 | TBX3 2.6289 | WNT9A 2.5288 | BMPR1A 2.4359 | ECE1 2.4001 | GNA12 2.3370 | GLI3 2.3270 | ACD 2.2550 | AFF3 2.2363 | SKI 2.1799 | LRP5 2.1685 | LRP4 2.1606 | PTCH1 2.1082 | TWIST1 2.0979 | ALDH1A2 2.0957 | WNT3 2.0876 | LRP6 2.0780 | ALX4 2.0645 | WNT7A 2.0616 | LMBR1 2.0526 | FGF4 2.0087 | TBX5 1.9756 | TULP3 1.9626 | FGF9 1.8959 | GPC3 1.8708 | HOXD11 1.8126 | HOXD13 | HOXD9 1.8126 | RSPO2 1.8089 | MUSTN1 1.7901 | SP9 1.7865 | GNAQ 1.7558 | CYP26B1 1.7548 | LEF1 1.7470 | CREBBP 1.7131 | OSR2 1.6982 | GJA5 1.6874 | NOTCH1 1.6712 | GREM1 1.6695 | HNF1A 1.6105 | PBX2 1.5913 | BMP7 1.5842 | FGFR1 1.5730 | TBX4 1.5316 | IFT52 1.5182 | MSX1 1.4876 | DICER1 1.4798 | FLVCR1 1.4767 | FBXW4 1.4676 | MMP13 1.4661 | ZNF358 1.4312 | RDH10 1.3839 | NOTCH2 1.3830 | RPGRIP1L 1.3825 | WNT5A 1.3655 | GLI2 1.3606 | IFT122 1.3452 | PRRX1 1.2712 | SHH 1.2438 | IMPAD1 1.2243 | HAND2 1.1943 | TFAP2A 1.1936 | GNAS 1.1857 | RARG 1.1840 | SALL1 1.1703 | RAB23 1.1331 | PRRX2 1.1307 | BMP4 1.1081 | MED1 1.0961 | MSX2 1.0645 | PSEN1 1.0274 | CHD7 1.0210 | PITX1 0.9816 | OSR1 0.9759 | GAS1 0.9741 | FBN2 0.9552 | EN1 0.9522 | SP8 0.9512 | HDAC2 0.9044 | DLX6 0.8896 | IFT88 0.8853 | DLX5 0.8523 | HDAC1 0.8048 | SFRP2 0.7657 | NOG 0.6617 | KIAA1715 0.6331 | GDF5 0.6266 | CTNNB1 0.5466 | EVI1 | LNP | RALDH2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
water channel activity (boxplot) | 11 | 12 | 2.90073373261495 | 0.0018614503770115753 | 0.0334975854960834 | 0.014652014652014652 | AQP2 4.0312 | AQP5 4.0312 | AQP6 | AQP3 2.7086 | MIP 2.4009 | AQP7 2.1271 | PDPN 1.9883 | AQP4 1.8231 | AQP1 1.7153 | AQP9 1.5122 | AQP8 1.1305 | AQP7P3 0.5966 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of calcium ion transport (boxplot) | 146 | 146 | 2.8907793759786617 | 0.0019214389764641293 | 0.034138730323649946 | 0.014598540145985401 | AQP2 4.0312 | CAV1 3.7656 | GNAO1 3.7443 | INPP5K 3.5378 | MYLK 3.2871 | RYR2 3.1737 | CACNB4 3.1376 | EFCAB4B 2.9151 | CACNA1C 2.8754 | OPRM1 2.8228 | SLC8A1 2.7718 | LACRT 2.7283 | CACNG3 2.6709 | F2 2.6432 | LIME1 2.6410 | PKD2L1 2.5895 | CXCL12 2.5696 | CAMK2D 2.5615 | ADCYAP1R1 2.5080 | TPCN2 2.5016 | STIM1 2.4544 | PLCG2 2.4205 | SESTD1 2.4004 | VDR 2.3912 | CAV3 2.3881 | P2RX5 2.3388 | NOS1 2.3035 | AGT 2.2659 | CACNG4 2.2546 | CAMK2B 2.2519 | NKX2-5 2.2385 | GLP1R 2.2306 | CACNB2 2.2123 | HOMER1 2.1943 | EGF 2.1937 | CAMK2G 2.1818 | JPH3 2.1788 | BCL2 2.1766 | CACNA1D 2.1182 | RHOC 2.1005 | RCVRN 2.0984 | CACNA1E 2.0970 | CCKAR 2.0865 | SLC30A1 2.0329 | IL1RAPL1 2.0206 | CACNA2D1 1.9982 | PKD2 1.9879 | SNCA 1.9846 | PTGS2 1.9806 | GAS6 1.9676 | CACNG7 1.9540 | P2RX1 1.9501 | JPH1 1.9422 | OPRD1 1.9420 | ASPH 1.9379 | CACNA1A 1.9305 | CCL4 1.9161 | SLN 1.8957 | JAK3 1.8666 | P2RX7 1.8574 | CACNA1B 1.8481 | CACNG1 1.8336 | DRD4 1.8319 | MGEA5 1.8243 | FFAR1 1.8156 | CCL5 1.8122 | ZP3 1.7758 | LHCGR 1.7607 | ITGAV 1.7509 | CASQ1 1.6978 | CACNG6 1.6930 | CACNG5 1.6745 | ICAM1 1.6718 | NOS3 1.6288 | TRPC4 1.6274 | NCS1 1.6216 | CACNA1I 1.6100 | ADRB1 1.6047 | LYN 1.5986 | WFS1 1.5881 | DRD2 1.5853 | CAPN3 1.5788 | RYR1 1.5561 | MYO5A 1.5529 | TRIM27 1.5287 | GJA1 1.5265 | P2RX4 1.5095 | DRD1 1.4777 | F2RL3 1.4758 | GIMAP5 1.4739 | STIM2 1.4476 | TRPC6 1.4311 | F2R 1.4291 | MS4A2 1.4184 | CACNA1S 1.3954 | P2RX3 1.3783 | FKBP1A 1.3770 | CACNG2 1.3692 | LILRB2 1.3636 | DIAPH1 1.3602 | PML 1.3600 | TRPC3 1.3214 | FKBP1B 1.3101 | ADORA2A 1.3027 | CACNG8 1.2699 | PDGFRB 1.2307 | CCR1 1.2203 | GCG 1.2112 | CASR 1.2002 | XCL1 1.1948 | LPAR3 1.1870 | CACNB1 1.1775 | PLCG1 1.1759 | ADRA2A 1.1742 | TSPO 1.1685 | MCHR1 1.1656 | TRPV2 1.1404 | JPH2 1.1317 | PTK2B 1.1280 | CALM2 1.1102 | GRIN3B 1.0627 | ADRB2 1.0467 | BDKRB1 1.0309 | PDGFB 1.0240 | CREB3 0.9695 | TGFB1 0.9693 | WNK3 0.9692 | TRPC1 0.9629 | CACNA1F 0.9583 | CCL3 0.9396 | PLN 0.9193 | IL13 0.8304 | TMEM66 0.8252 | CALCA 0.8098 | EDNRA 0.8058 | BAK1 0.7850 | LILRB1 0.7574 | CACNB3 0.7536 | P2RX2 0.6514 | THY1 0.6002 | ORAI1 0.5808 | HCRT 0.5645 | GNAI2 0.5640 | CTNNB1 0.5466 | PLA2G1B 0.4953 | JPH4 0.4863 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of organelle organization (boxplot) | 182 | 189 | 2.8855566256259397 | 0.001953610832683972 | 0.03458457437860104 | 0.01818181818181818 | ARHGEF10 3.8915 | CAV1 3.7656 | CCL24 3.7243 | NIPBL 3.6793 | DNMT1 3.5891 | NF2 3.2554 | INSR 3.1624 | PHIP 3.1621 | PAXIP1 3.1608 | FES 3.1088 | TNF 3.0639 | BAX 3.0299 | HOXA13 2.9921 | ARPC4 2.9695 | SYNPO 2.9309 | PROX1 2.8868 | PRKCE 2.7354 | BID 2.7152 | SNAI2 2.6919 | BBC3 2.6870 | EPHA1 2.5465 | SLAIN2 2.5206 | PPARGC1A 2.4496 | SERPINF2 2.4022 | HRK 2.3983 | CAV3 2.3881 | SORBS3 2.3613 | EDN1 2.3459 | PLA2G4A 2.3298 | CCR7 2.3166 | NOS1 2.3035 | FHOD1 2.2999 | TNKS2 2.2784 | MAP1B 2.2447 | ARL2 2.2292 | AMOT 2.2199 | NUSAP1 2.2108 | GFI1B 2.2059 | EGF 2.1937 | WNT11 2.1927 | NCOR1 2.1739 | LRP5 2.1685 | CD28 2.1569 | LPIN1 2.1486 | SMAD3 2.1433 | CCL26 2.1094 | RHOC 2.1005 | MEN1 2.0976 | ROCK2 2.0790 | TRPV4 2.0262 | ACTR3 2.0099 | MAP3K1 1.9924 | WDR61 1.9782 | IGF2 1.9742 | INS | KATNB1 1.9703 | DRD3 1.9435 | CTBP1 1.9311 | NSMCE2 1.9229 | MLLT11 1.9111 | FER 1.8987 | RHOA 1.8947 | IL1B 1.8813 | TEK 1.8630 | MAPK3 1.8628 | DLG1 1.8617 | P2RX7 1.8574 | SREBF1 1.8466 | CTR9 1.8327 | MUC1 1.8194 | ANXA1 1.8032 | TNKS 1.7942 | MFF 1.7707 | MTOR 1.7516 | PMAIP1 1.7492 | MYB 1.7428 | VIL1 1.7405 | MYLK3 1.7219 | KISS1R 1.7173 | PFN2 1.7072 | BRCA1 1.7066 | JARID2 1.7060 | BAIAP2L1 1.6951 | NES 1.6950 | BAD 1.6791 | SCIN 1.6737 | DOC2B 1.6682 | TGFA 1.6583 | CDC42EP5 1.6302 | RPS6KA4 1.6294 | CLIP1 1.6222 | F2RL1 1.6183 | TAC1 1.6069 | IGF1 1.6014 | TPM1 1.5971 | ARRB1 1.5906 | DMRT1 1.5870 | CDK5 1.5715 | RPS6KA5 1.5702 | MUL1 1.5551 | KIAA1324 1.5468 | LMAN1 1.5355 | FOXP3 1.5343 | PSRC1 1.5268 | PRKCQ 1.5129 | APC 1.5096 | SMC5 1.5090 | TAL1 1.4925 | EP300 1.4888 | HCK 1.4790 | IL1A 1.4740 | MARCH5 1.4717 | NCK2 1.4470 | ARHGEF10L 1.4113 | TNFSF10 1.4107 | ANXA2 1.4037 | PLK1 1.4034 | PTEN 1.3846 | DLGAP5 1.3708 | BAG4 1.3675 | PML 1.3600 | TACR1 1.3533 | TP53 1.3523 | EPGN 1.3426 | CDC42EP2 1.3369 | BRD7 1.3186 | CCL11 1.3027 | RANBP1 1.2934 | JMY 1.2927 | SDC4 1.2900 | ARHGEF15 1.2884 | SFRP1 1.2842 | PLEK 1.2748 | BIK 1.2696 | CCL21 1.2605 | NCKAP1L 1.2593 | DSTN 1.2412 | PDGFRB 1.2307 | BCL2L11 1.2301 | TERF1 1.2249 | PLXNA3 1.2147 | PPM1F 1.1863 | PINK1 1.1846 | LIMK1 1.1825 | RB1 1.1822 | DNM1L 1.1573 | ARF6 1.1563 | CDKN1B 1.1519 | MET 1.1441 | PAK1 1.1424 | AURKA 1.1367 | PTK2B 1.1280 | STMN2 1.1280 | POT1 1.1126 | EDN3 1.1118 | BMF 1.1100 | APOPT1 1.0707 | DNMT3B 1.0326 | PDGFB 1.0240 | ESPL1 1.0132 | TINF2 0.9695 | TGFB1 0.9693 | CTGF 0.9616 | BNIP3 0.9338 | WASH2P 0.9218 | PEBP1 0.9211 | TERF2 0.8944 | GPR65 0.8893 | EREG 0.8038 | FAM162A 0.8016 | PPM1E 0.7885 | TMED9 0.7869 | BAK1 0.7850 | NCK1 0.7460 | UBE2N 0.7395 | SURF4 0.7107 | OGT 0.6705 | CCNB1 0.5640 | PDXP 0.5140 | MAPT 0.4387 | PLK4 0.4145 | ARPC2 0.4034 | WASH1 0.2959 | C4orf49 | F5H0A2 | FRAP1 | WASH3P | WASH4P | WASH6P | ||||||||||||||||||
MHC class II protein complex (boxplot) | 14 | 19 | 2.883814066283492 | 0.00196445327003425 | 0.03465096995446695 | 0.018115942028985508 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | HLA-DMB 2.6120 | HLA-DQA1 2.3613 | HLA-DRB1 2.1516 | HLA-DRB5 1.8305 | HLA-DQB1 1.7437 | HLA-DOB 1.5897 | TAP2 1.5897 | HLA-DQA2 1.5353 | HLA-DQB2 | HLA-DPA1 1.4883 | HLA-DPB1 | HLA-DRA 1.2787 | HLA-DRB3 1.2503 | CD74 1.0390 | E7ENX8 | F6UB75 | HLA-DRB4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
pattern binding (boxplot) | 191 | 198 | 2.8814085223113137 | 0.0019795106861193457 | 0.03479096838985296 | 0.018050541516245487 | VCAN 3.6291 | IMPG2 3.5455 | NAV2 3.4966 | CHRD 3.3515 | LIPI 3.0539 | VEGFA 3.0488 | ADAMTS1 2.9721 | COL23A1 2.9611 | VEGFB 2.9601 | CHODL 2.9581 | TINAG 2.9207 | SLIT2 2.8500 | RSPO1 2.8111 | COLQ 2.7875 | COL13A1 2.7836 | HABP2 2.7788 | VIT 2.7774 | FGFR2 2.7650 | HAPLN1 2.6913 | SPOCK3 2.6847 | STBD1 2.6787 | MSTN 2.6651 | ENDOU 2.6418 | PCOLCE 2.6139 | PTX3 2.6077 | APOA5 2.5911 | FGF12 2.5490 | FGF7 2.5131 | PRG4 2.4566 | THBS2 2.4552 | ACAN 2.4524 | LTF 2.4305 | CD44 2.4166 | TINAGL1 2.4153 | PLA2G5 2.3447 | C6orf15 2.3328 | COL25A1 2.3088 | CECR1 2.2636 | FGF1 2.2613 | ABI3BP 2.2421 | CLEC3B 2.2058 | ENG 2.2047 | PRELP 2.1772 | HDGF 2.1451 | PGLYRP4 2.1373 | APP 2.1303 | TNXB 2.1180 | PTCH1 2.1082 | STAB2 2.0287 | APLP2 2.0226 | CHIA 2.0164 | HAPLN3 2.0138 | FSTL1 2.0127 | FGF4 2.0087 | SERPIND1 2.0007 | SELL 1.9952 | LPL 1.9485 | FN1 1.9294 | COL5A1 1.9082 | AZU1 1.9033 | ELANE | FGF9 1.8959 | SUSD2 1.8949 | STAB1 1.8699 | SERPINC1 1.8522 | EPM2A 1.8460 | VTN 1.8442 | FGF14 1.8434 | PF4V1 1.8311 | LAMC2 1.8307 | EGFLAM 1.8194 | THBS3 1.8194 | CCL5 1.8122 | RSPO2 1.8089 | HRG 1.8045 | ADAMTS8 1.7936 | LYVE1 1.7915 | ODZ1 1.7867 | MPO 1.7849 | BGN 1.7750 | EMR2 1.7564 | PGLYRP1 1.7352 | THBS4 1.7325 | LTBP2 1.7261 | DPYSL3 1.7243 | KNG1 1.7229 | PTN 1.7220 | CRISPLD2 1.7077 | TGFBR3 1.7014 | PCSK6 1.6942 | PPP1R3F 1.6905 | ZNF146 1.6646 | ANG 1.6605 | CYR61 1.6494 | FGFRL1 1.6492 | CXCL13 1.6464 | NRP2 1.6343 | SERPINE2 1.6272 | LIPC 1.6053 | HMMR 1.6027 | TGFBR2 1.5967 | PCOLCE2 1.5906 | SMOC2 1.5879 | NRP1 1.5851 | NLRP3 1.5820 | CCDC80 1.5762 | FGFR1 1.5730 | EPYC 1.5664 | ENPP3 1.5651 | SELP 1.5609 | HSD17B12 1.5489 | SUSD5 1.5425 | PF4 1.5319 | ENPP2 1.5115 | APLP1 1.4983 | PGLYRP3 1.4807 | CCL23 1.4476 | RNF146 1.4459 | GPNMB 1.4422 | HBEGF 1.4417 | FIBCD1 1.4403 | APOE 1.4398 | GPCPD1 1.4356 | FGFBP3 1.4193 | PTPRC 1.4182 | CLEC7A 1.3986 | PRG2 1.3783 | TLR2 1.3663 | CXCL6 1.3633 | NDNF 1.3563 | COL5A3 1.3492 | LPA 1.3392 | FGFBP1 1.3388 | LIPG 1.3223 | PODXL2 1.3179 | ABP1 1.3087 | CCL7 1.3027 | SFRP1 1.2842 | KAL1 1.2799 | NCAN 1.2768 | MDK 1.2489 | APOB 1.2451 | SHH 1.2438 | APOH 1.2376 | PGLYRP2 1.2231 | ADAMTS3 1.2193 | LRPAP1 1.2147 | BCAN 1.2096 | ENPP1 1.1901 | HAPLN4 1.1820 | SOST 1.1782 | RPL29 1.1581 | SPOCK2 1.1539 | CEL 1.1461 | FBLN7 1.1430 | FGFR4 1.1354 | FGF2 1.1278 | RPL22 1.1263 | CHIT1 1.1246 | RSPO4 1.1140 | BMP4 1.1081 | LAYN 1.0936 | F11 1.0932 | RSPO3 1.0908 | POSTN 1.0666 | HAPLN2 1.0632 | TNFAIP6 1.0552 | DCN 1.0126 | COMP 1.0103 | NOD1 1.0056 | CCL15 0.9935 | SERPINA5 0.9719 | SOD3 0.9639 | CTGF 0.9616 | MAMDC2 0.9200 | CHI3L1 0.8801 | GNS 0.8531 | PAFAH1B1 0.8148 | CCL8 0.7797 | ECM2 0.7676 | LTBP4 0.7647 | PGF 0.7441 | AAMP 0.7422 | THBS1 0.7292 | FGF10 0.7055 | NOD2 0.6871 | CCL2 | CTSG 0.6388 | ZNF207 0.5900 | AGL 0.5770 | LIPH 0.5445 | HYAL2 0.2244 | KGFLP2 0.1912 | CSPG3 variant protein | G6B | KGFLP1 | RPESP | tmplocus3 | |||||||||
polysaccharide binding (boxplot) | 191 | 198 | 2.8814085223113137 | 0.0019795106861193457 | 0.03479096838985296 | 0.018050541516245487 | VCAN 3.6291 | IMPG2 3.5455 | NAV2 3.4966 | CHRD 3.3515 | LIPI 3.0539 | VEGFA 3.0488 | ADAMTS1 2.9721 | COL23A1 2.9611 | VEGFB 2.9601 | CHODL 2.9581 | TINAG 2.9207 | SLIT2 2.8500 | RSPO1 2.8111 | COLQ 2.7875 | COL13A1 2.7836 | HABP2 2.7788 | VIT 2.7774 | FGFR2 2.7650 | HAPLN1 2.6913 | SPOCK3 2.6847 | STBD1 2.6787 | MSTN 2.6651 | ENDOU 2.6418 | PCOLCE 2.6139 | PTX3 2.6077 | APOA5 2.5911 | FGF12 2.5490 | FGF7 2.5131 | PRG4 2.4566 | THBS2 2.4552 | ACAN 2.4524 | LTF 2.4305 | CD44 2.4166 | TINAGL1 2.4153 | PLA2G5 2.3447 | C6orf15 2.3328 | COL25A1 2.3088 | CECR1 2.2636 | FGF1 2.2613 | ABI3BP 2.2421 | CLEC3B 2.2058 | ENG 2.2047 | PRELP 2.1772 | HDGF 2.1451 | PGLYRP4 2.1373 | APP 2.1303 | TNXB 2.1180 | PTCH1 2.1082 | STAB2 2.0287 | APLP2 2.0226 | CHIA 2.0164 | HAPLN3 2.0138 | FSTL1 2.0127 | FGF4 2.0087 | SERPIND1 2.0007 | SELL 1.9952 | LPL 1.9485 | FN1 1.9294 | COL5A1 1.9082 | AZU1 1.9033 | ELANE | FGF9 1.8959 | SUSD2 1.8949 | STAB1 1.8699 | SERPINC1 1.8522 | EPM2A 1.8460 | VTN 1.8442 | FGF14 1.8434 | PF4V1 1.8311 | LAMC2 1.8307 | EGFLAM 1.8194 | THBS3 1.8194 | CCL5 1.8122 | RSPO2 1.8089 | HRG 1.8045 | ADAMTS8 1.7936 | LYVE1 1.7915 | ODZ1 1.7867 | MPO 1.7849 | BGN 1.7750 | EMR2 1.7564 | PGLYRP1 1.7352 | THBS4 1.7325 | LTBP2 1.7261 | DPYSL3 1.7243 | KNG1 1.7229 | PTN 1.7220 | CRISPLD2 1.7077 | TGFBR3 1.7014 | PCSK6 1.6942 | PPP1R3F 1.6905 | ZNF146 1.6646 | ANG 1.6605 | CYR61 1.6494 | FGFRL1 1.6492 | CXCL13 1.6464 | NRP2 1.6343 | SERPINE2 1.6272 | LIPC 1.6053 | HMMR 1.6027 | TGFBR2 1.5967 | PCOLCE2 1.5906 | SMOC2 1.5879 | NRP1 1.5851 | NLRP3 1.5820 | CCDC80 1.5762 | FGFR1 1.5730 | EPYC 1.5664 | ENPP3 1.5651 | SELP 1.5609 | HSD17B12 1.5489 | SUSD5 1.5425 | PF4 1.5319 | ENPP2 1.5115 | APLP1 1.4983 | PGLYRP3 1.4807 | CCL23 1.4476 | RNF146 1.4459 | GPNMB 1.4422 | HBEGF 1.4417 | FIBCD1 1.4403 | APOE 1.4398 | GPCPD1 1.4356 | FGFBP3 1.4193 | PTPRC 1.4182 | CLEC7A 1.3986 | PRG2 1.3783 | TLR2 1.3663 | CXCL6 1.3633 | NDNF 1.3563 | COL5A3 1.3492 | LPA 1.3392 | FGFBP1 1.3388 | LIPG 1.3223 | PODXL2 1.3179 | ABP1 1.3087 | CCL7 1.3027 | SFRP1 1.2842 | KAL1 1.2799 | NCAN 1.2768 | MDK 1.2489 | APOB 1.2451 | SHH 1.2438 | APOH 1.2376 | PGLYRP2 1.2231 | ADAMTS3 1.2193 | LRPAP1 1.2147 | BCAN 1.2096 | ENPP1 1.1901 | HAPLN4 1.1820 | SOST 1.1782 | RPL29 1.1581 | SPOCK2 1.1539 | CEL 1.1461 | FBLN7 1.1430 | FGFR4 1.1354 | FGF2 1.1278 | RPL22 1.1263 | CHIT1 1.1246 | RSPO4 1.1140 | BMP4 1.1081 | LAYN 1.0936 | F11 1.0932 | RSPO3 1.0908 | POSTN 1.0666 | HAPLN2 1.0632 | TNFAIP6 1.0552 | DCN 1.0126 | COMP 1.0103 | NOD1 1.0056 | CCL15 0.9935 | SERPINA5 0.9719 | SOD3 0.9639 | CTGF 0.9616 | MAMDC2 0.9200 | CHI3L1 0.8801 | GNS 0.8531 | PAFAH1B1 0.8148 | CCL8 0.7797 | ECM2 0.7676 | LTBP4 0.7647 | PGF 0.7441 | AAMP 0.7422 | THBS1 0.7292 | FGF10 0.7055 | NOD2 0.6871 | CCL2 | CTSG 0.6388 | ZNF207 0.5900 | AGL 0.5770 | LIPH 0.5445 | HYAL2 0.2244 | KGFLP2 0.1912 | CSPG3 variant protein | G6B | KGFLP1 | RPESP | tmplocus3 | |||||||||
heart process (boxplot) | 35 | 35 | 2.881330216398655 | 0.0019800025958081058 | 0.03479096838985296 | 0.017921146953405017 | SCN3B 4.2468 | MAP2K6 3.6149 | PSEN2 3.3139 | TCAP 3.2295 | RYR2 3.1737 | VEGFB 2.9601 | ANK2 2.8691 | CAMK2D 2.5615 | RPS6KA2 2.5126 | SCN5A 2.2668 | NKX2-5 2.2385 | CXADR 2.1888 | TNNI3 2.0145 | GAA 1.9633 | MYBPC3 1.9461 | PPP1R13L 1.9069 | GPX1 1.8947 | MYL3 1.8709 | TNNC1 1.8440 | TPM1 1.5971 | MYL2 1.5502 | MYL1 1.3574 | PIK3CA 1.3325 | SCN1B 1.3219 | ATG5 1.3205 | MYL4 1.2440 | ACTC1 1.1031 | MYLK2 1.0997 | TAZ 1.0762 | ADRBK1 1.0662 | SCN2B 1.0517 | SMAD5 0.8825 | SOD1 0.8543 | ACE 0.7753 | MAP2K3 0.5826 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sensory perception of sound (boxplot) | 111 | 115 | 2.879580323371443 | 0.001991024240675987 | 0.03479096838985296 | 0.017857142857142856 | COL11A2 4.6854 | GPR98 4.6366 | OTOA 3.7072 | NIPBL 3.6793 | PCDH15 3.5572 | NAV2 3.4966 | HEXA 3.0328 | OTOS 3.0083 | CDH23 2.9737 | ATP2B2 2.8342 | GRM7 2.8268 | KCNQ4 2.8155 | ASIC2 2.7474 | BARHL1 2.7381 | SNAI2 2.6919 | KCNQ1 2.5850 | CLRN1 2.3729 | OTOR 2.3610 | HEXB 2.3391 | CASP3 2.3272 | COL4A3 2.2501 | TMPRSS3 2.2184 | SLC1A3 2.1895 | ATP6V1B1 2.1332 | MYO3A 2.1330 | USH2A 2.0822 | GABRA5 2.0812 | EYA1 2.0489 | CHRNA10 2.0484 | LOXHD1 2.0404 | SLC17A8 2.0171 | AXIN1 1.9756 | TH 1.9742 | SOBP 1.9633 | MYC 1.9575 | LHFPL5 1.9424 | MYO6 1.9297 | GPX1 1.8947 | GRXCR1 1.8854 | TBL1X 1.8800 | TBX1 1.8661 | SPTBN4 1.8647 | KCNE1 1.8416 | ALMS1 1.8311 | AQP4 1.8231 | ALDH7A1 1.8048 | GJB3 1.7960 | TPRN 1.7859 | PAX3 1.7479 | EML2 1.7347 | HPN 1.7202 | GABRB2 1.7081 | TIMM10 1.7062 | MYO7A 1.7012 | CLIC5 1.6546 | ATP6V0A4 1.6520 | OTOF 1.6397 | MARVELD2 1.6375 | MYO1A 1.6056 | WFS1 1.5881 | TMC1 1.5815 | FGFR1 1.5730 | SLC26A4 1.5569 | MKKS 1.5151 | CHRNA9 1.5108 | CRYM 1.5098 | KPTN 1.4933 | ZNF354A 1.4877 | COL1A1 1.4835 | PGAP1 1.4486 | COL11A1 1.4339 | ESPN 1.4330 | USH1C 1.4192 | CEACAM16 1.3793 | DIAPH1 1.3602 | LRTOMT 1.3465 | COCH 1.3375 | POU4F2 1.3305 | COL2A1 1.3191 | TIMM9 1.3046 | GJB2 1.2907 | POU4F3 1.2812 | HOXA1 1.2096 | TMIE 1.2034 | TFAP2A 1.1936 | FBXO11 1.1877 | NDUFB9 1.1686 | NDP 1.1646 | TECTA 1.1635 | SLC26A5 1.1553 | CDKN1B 1.1519 | DFNA5 1.1301 | GJB6 1.1136 | MYCBPAP 1.0619 | CHD7 1.0210 | SLC12A2 0.9968 | SPRY2 0.9548 | CHRNB2 0.9425 | SOD1 0.8543 | USH1G 0.8160 | WDR1 0.8122 | SIX1 0.8071 | MYO15A 0.7632 | FZD4 0.7448 | TIMM8B 0.7168 | GJC3 0.7123 | TBX18 0.6120 | TIMM13 0.6015 | SOX2 0.5800 | POU3F4 0.4645 | STRC 0.4507 | OTOG | PJVK | RFT2 | WHRN | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
divalent inorganic cation transport (boxplot) | 172 | 173 | 2.8792817950936747 | 0.001992910064075981 | 0.03479096838985296 | 0.017793594306049824 | SLC39A7 4.4996 | CAV1 3.7656 | PDE2A 3.7330 | ANXA6 3.7088 | FYN 3.7055 | PSEN2 3.3139 | RYR2 3.1737 | GRIN3A 3.1467 | CUL5 3.0470 | CDH23 2.9737 | CHERP 2.9269 | EFCAB4B 2.9151 | CACNA1C 2.8754 | ATP2B2 2.8342 | BSPRY 2.7881 | SLC8A1 2.7718 | PRKCE 2.7354 | SLC39A10 2.7281 | BBC3 2.6870 | ABCB6 2.6848 | CACNG3 2.6709 | RYR3 2.5711 | CAMK2D 2.5615 | TPCN2 2.5016 | STIM1 2.4544 | PLCG2 2.4205 | VDR 2.3912 | SLC39A2 2.3812 | TCN2 2.3721 | MT3 2.3391 | SLC39A11 2.3292 | CCR7 2.3166 | CAMK2B 2.2519 | CSN2 2.2365 | GLP1R 2.2306 | CACNB2 2.2123 | TRPV1 2.1980 | JPH3 2.1788 | ADRA1A 2.1619 | ITPR2 2.1594 | SLC39A1 2.1519 | CAMK2A 2.1496 | CACNA1D 2.1182 | GIF 2.0530 | SLC30A1 2.0329 | TRPV4 2.0262 | CACNA2D1 1.9982 | PKD2 1.9879 | SLC24A4 1.9794 | RAMP3 1.9727 | CACNG7 1.9540 | P2RX1 1.9501 | SLC30A9 1.9490 | JPH1 1.9422 | CLCA1 1.9393 | ASPH 1.9379 | NIPAL4 1.9364 | HTR2B 1.9303 | SLC8A3 1.9072 | SLN 1.8957 | CACHD1 1.8823 | CYSLTR1 1.8716 | P2RX7 1.8574 | ASIC1 1.8572 | CALCRL 1.8557 | TRPM1 1.8355 | CCL5 1.8122 | GJA4 1.7960 | EFCAB4A 1.7743 | SLC24A1 1.7667 | ITPR3 1.7657 | SLC11A1 1.7405 | SLC30A8 1.7213 | TUSC3 1.7094 | CACNG6 1.6930 | SLC39A9 1.6923 | ATP2A2 1.6834 | SLC24A5 1.6778 | IBTK 1.6756 | CHRNA7 1.6719 | SLC24A6 1.6711 | PANX1 1.6650 | TRPM2 1.6363 | REST 1.6316 | TRPC4 1.6274 | CACNA1I 1.6100 | TRPC5 1.6072 | MCU 1.6010 | SLC39A8 1.5959 | DRD2 1.5853 | HTR2A 1.5850 | NPY 1.5849 | RYR1 1.5561 | ATP2C1 1.5260 | KCNN4 1.5095 | P2RX4 1.5095 | SLC39A3 1.5021 | SLC8A2 1.4933 | TRPV5 1.4897 | TPT1 1.4838 | RAMP1 1.4694 | TCN1 1.4655 | STIM2 1.4476 | ITPR1 1.4342 | MCOLN1 1.4312 | F2R 1.4291 | PPP3CA 1.4235 | MS4A2 1.4184 | PTPRC 1.4182 | SLC39A12 1.4055 | SLC3A2 1.4035 | MAGT1 1.4030 | CACNA1S 1.3954 | ATP2A1 1.3612 | SLC39A13 1.3558 | SLC39A14 1.3358 | TRPC3 1.3214 | LCK 1.3129 | SLC30A7 1.3127 | FKBP1B 1.3101 | SLC11A2 1.3019 | CYP27B1 1.2985 | CACNG8 1.2699 | GRIN1 1.2637 | CCL19 1.2605 | CCL21 | SLC30A5 1.2299 | BHLHA15 1.2296 | CCR1 1.2203 | CASR 1.2002 | CHRNA4 1.2001 | XCL1 1.1948 | PLCG1 1.1759 | CCR5 1.1711 | SLC39A6 1.1470 | TRPV2 1.1404 | JPH2 1.1317 | FGF2 1.1278 | SLC30A2 1.1276 | SLC30A4 1.1168 | NIPA1 1.1054 | SLC30A10 1.0813 | NMUR2 1.0684 | GRIN3B 1.0627 | PSEN1 1.0274 | ATP2A3 0.9855 | ZDHHC13 0.9786 | CORO1A 0.9727 | TRPC1 0.9629 | CTGF 0.9616 | RAMP2 0.9523 | HTR2C 0.9475 | CHRNB2 0.9425 | CCL3 0.9396 | PLN 0.9193 | NIPAL1 0.9149 | MICU1 0.8856 | PKD1 0.8841 | MMGT1 0.8813 | SRI 0.8747 | NIPA2 0.8731 | TMEM66 0.8252 | CCL8 0.7797 | NMUR1 0.7701 | CACNB3 0.7536 | SLC39A5 0.7353 | CLDN16 0.6937 | ZDHHC17 0.6863 | SLC30A6 0.6020 | TRPV6 0.5852 | XCR1 0.5364 | PLCZ1 0.4867 | JPH4 0.4863 | ||||||||||||||||||||||||||||||||||
plasma lipoprotein particle assembly (boxplot) | 11 | 12 | 2.871789572738104 | 0.0020407732417205837 | 0.03523398607437021 | 0.01773049645390071 | ABCA1 5.6064 | SOAT1 3.1809 | APOA1 3.0248 | APOC3 | APOA4 2.5911 | APOM 2.1586 | DGAT1 1.7111 | APOE 1.4398 | APOC1 1.3441 | APOB 1.2451 | APOA2 0.8951 | SOAT2 0.7990 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
protein-lipid complex assembly (boxplot) | 11 | 12 | 2.871789572738104 | 0.0020407732417205837 | 0.03523398607437021 | 0.01773049645390071 | ABCA1 5.6064 | SOAT1 3.1809 | APOA1 3.0248 | APOC3 | APOA4 2.5911 | APOM 2.1586 | DGAT1 1.7111 | APOE 1.4398 | APOC1 1.3441 | APOB 1.2451 | APOA2 0.8951 | SOAT2 0.7990 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lactation (boxplot) | 37 | 38 | 2.8647917912085554 | 0.0020864175513894967 | 0.035769249670488 | 0.017605633802816902 | PRLR 4.7596 | CAV1 3.7656 | ERBB4 3.2809 | CDO1 3.1705 | VEGFA 3.0488 | APRT 3.0059 | PPAT 2.6276 | SLC29A2 2.5230 | ATP7B 2.4203 | VDR 2.3912 | OXTR 2.3881 | XDH 2.2615 | AGPAT6 2.0214 | BCAT2 2.0139 | CCND1 1.9690 | USF2 1.8819 | HK2 1.8360 | GC 1.8069 | HIF1A 1.6618 | GHRHR 1.6541 | DDR1 1.6458 | PRL 1.5478 | FOXB1 1.5142 | STAT5A 1.5114 | SLC29A1 1.3140 | NEURL 1.2759 | SLC6A3 1.1970 | CHUK 1.1789 | MET 1.1441 | PMCH 1.1212 | SLC30A4 1.1168 | MED1 1.0961 | STAT5B 1.0063 | APLN 0.9429 | CSN3 0.8047 | EIF2AK3 0.7800 | CREB1 0.5390 | MT-CO2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of protein import into nucleus, translocation (boxplot) | 17 | 17 | 2.8601750712208953 | 0.0021170359757507473 | 0.03616726495635717 | 0.017543859649122806 | SIRT1 7.4176 | PDE2A 3.7330 | OGG1 2.8679 | MAVS 2.3274 | GAS6 1.9676 | IL6 1.7153 | HNF4A 1.7052 | IGF1 1.6014 | CDKN1A 1.5286 | TXN 1.5088 | EP300 1.4888 | JAK2 1.4043 | UBR5 1.3446 | CDK1 1.2389 | TNFRSF1A 1.1656 | MED1 1.0961 | TMEM173 0.8723 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
phospholipid-translocating ATPase activity (boxplot) | 15 | 15 | 2.853761859714216 | 0.0021602452335869327 | 0.03677685787911412 | 0.017482517482517484 | ATP9A 3.8389 | ATP11A 3.7283 | ATP8A2 3.6048 | ATP8B2 3.0740 | ATP10D 2.2069 | ATP10A 2.1905 | ATP8B4 1.9597 | ABCA4 1.9148 | ATP9B 1.7613 | ATP10B 1.5905 | ATP8B1 1.3825 | ATP11B 1.2915 | ATP8A1 1.2627 | ATP8B3 0.9821 | ATP11C 0.5439 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
negative regulation of response to cytokine stimulus (boxplot) | 28 | 28 | 2.853536767948063 | 0.0021617762203143265 | 0.03677685787911412 | 0.017421602787456445 | CAV1 3.7656 | MAP2K5 2.8555 | SLIT2 2.8500 | IL1RN 2.8456 | PXDN 2.8160 | PTPRF 2.5339 | NLRC5 2.5068 | SLIT3 2.4489 | IL36RN 2.2828 | ROBO1 2.1673 | GAS6 1.9676 | IRAK3 1.9617 | MAPK7 1.8453 | AES 1.8172 | CCL5 1.8122 | GSTP1 1.7474 | PALM3 1.6861 | IL6ST 1.6793 | PPARG 1.6692 | F2RL1 1.6183 | DNAJA3 1.4206 | PTPRC 1.4182 | ADIPOQ 1.3289 | NR1H3 1.3265 | NR1H2 1.1632 | ZNF675 1.1570 | KLF4 1.0448 | SIGIRR 0.7797 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
receptor-mediated endocytosis (boxplot) | 90 | 91 | 2.8507139850793513 | 0.002181059391650697 | 0.03687424286368618 | 0.017361111111111112 | PICALM 3.8576 | CAV1 3.7656 | GRB2 3.5564 | PLA2R1 3.4416 | SCARF1 3.2573 | GHR 3.1211 | DNM2 3.0383 | CUBN 2.9709 | RAB5A 2.6894 | FNBP1L 2.5333 | GRK4 2.5292 | LRP1B 2.5207 | LRP2 2.5159 | SORL1 2.4985 | AP1S1 2.3948 | HTR1B 2.3684 | CLEC9A 2.3525 | CNTN2 2.2820 | PLD2 2.2800 | FOLR1 2.0926 | LRP6 2.0780 | SCYL2 2.0365 | STAB2 2.0287 | DNM1 2.0164 | SNCA 1.9846 | NEDD4 1.9836 | SFTPD 1.9782 | RAMP3 1.9727 | MAPK1 1.9571 | DRD3 1.9435 | HTR2B 1.9303 | LDLR 1.9157 | STAB1 1.8699 | LRP1 1.8683 | HFE 1.8648 | MAPK3 1.8628 | M6PR 1.8584 | CALCRL 1.8557 | CLTCL1 1.8029 | CAP1 1.7921 | PPT1 | LRP3 1.7786 | MLC1 1.7589 | ADM 1.7485 | SNX17 1.7419 | ASGR1 1.7370 | PIP5K1C 1.7353 | PI4KB 1.7345 | SLC9A3 1.7279 | ADRBK2 1.6684 | CETP 1.6214 | VLDLR 1.6091 | NLGN3 1.5936 | ARRB1 1.5906 | DRD2 1.5853 | SNX9 1.5729 | ARRB2 1.4934 | CXCL16 1.4934 | IGF2R 1.4885 | RAMP1 1.4694 | MMP13 1.4661 | APOE 1.4398 | HIP1R 1.4332 | LDLRAP1 1.4279 | PDLIM7 1.3736 | FCHO2 1.3684 | LPA 1.3392 | CLN3 1.3063 | ADRB3 1.3060 | IL8 1.2857 | MSR1 1.2705 | CLTC 1.2691 | APOB 1.2451 | PIKFYVE 1.1741 | GTF2H2 1.1492 | GRIA1 1.1475 | CALCR 1.1467 | ADRBK1 1.0662 | ADRB2 1.0467 | CANX 0.9986 | ARHGAP27 0.9711 | RAMP2 0.9523 | ACHE 0.9394 | ULK1 0.9247 | FCHO1 0.8604 | CALCA 0.8098 | LILRB1 0.7574 | CXCR2 0.7197 | RABEPK 0.6930 | CXCR1 0.5615 | MRC1 0.5358 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ovum-producing ovary development (boxplot) | 79 | 81 | 2.8481433693612663 | 0.002198755456003232 | 0.037045238475971694 | 0.01730103806228374 | SIRT1 7.4176 | PCYT1B 7.2283 | SOHLH1 3.0802 | VEGFA 3.0488 | ROBO2 3.0085 | AMH 2.9749 | ADAMTS1 2.9721 | SLIT2 2.8500 | CHAT 2.7603 | FGF7 2.5131 | IQCJ-SCHIP1 2.4652 | SLIT3 2.4489 | MSH4 2.4326 | FSHR 2.4105 | SCHIP1 2.3967 | VGF 2.3948 | PLA2G4A 2.3298 | AGT 2.2659 | NRIP1 2.1803 | BCL2 2.1766 | CCND2 2.1625 | ACSBG1 2.1597 | FOXL2 2.1573 | FOXO3 2.0675 | IMMP2L 1.9821 | MMP14 1.9618 | DMC1 1.9224 | BMPR1B 1.9013 | NR5A1 1.8809 | EDN2 1.8797 | ESR1 1.8508 | ESR2 1.8459 | AFP 1.7611 | LHCGR 1.7607 | EIF2B4 1.7419 | CAPN5 1.7012 | STRA8 1.6857 | ICAM1 1.6718 | ANG 1.6605 | PDGFRA 1.6489 | NOS3 1.6288 | INHBA 1.6220 | KDR 1.5543 | MMP19 1.5508 | STAT5A 1.5114 | FANCG 1.4995 | CASP2 1.4160 | LEP 1.4143 | KITLG 1.3781 | CTNNA1 1.3657 | BMP15 1.3595 | NOBOX 1.3482 | UBE3A 1.2776 | TAF4 1.2681 | EIF2B5 1.2665 | PGR 1.2410 | FSHB 1.2331 | FOXC1 1.2136 | PLEKHA1 1.2069 | LFNG 1.1848 | ANGPT1 1.1416 | INHBB 1.1310 | ERMP1 1.1105 | BMP4 1.1081 | ADRBK1 1.0662 | STAT5B 1.0063 | GPR149 0.9780 | INHA 0.8631 | SOD1 0.8543 | SGPL1 0.8268 | BCL2L1 0.8053 | EREG 0.8038 | FZD4 0.7448 | SPO11 0.6482 | AHR 0.6079 | CENPI 0.4883 | CCNE1 0.4397 | EIF2B2 0.2862 | KGFLP2 0.1912 | KGFLP1 | estrogen receptor | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cell cortex (boxplot) | 176 | 178 | 2.847521241052759 | 0.0022030576861087336 | 0.037045238475971694 | 0.017241379310344827 | COL10A1 4.5846 | SEPT7 4.3221 | CAV1 3.7656 | CD302 3.7173 | FABP1 3.5813 | MAP2K2 3.3627 | PSEN2 3.3139 | MPP1 3.2590 | SEPT11 3.2438 | INPP5D 3.1650 | CTTN 3.0455 | GRM7 2.8268 | MELK 2.8083 | SPTBN1 2.7693 | SPTAN1 2.7684 | FGFR2 2.7650 | EPB49 2.6804 | SPTBN2 2.5986 | FNBP1L 2.5333 | KNCN 2.5329 | GRK4 2.5292 | AKAP12 2.5248 | SPTBN5 2.4987 | SEPT14 2.4840 | TPM3 2.4781 | FNBP1 2.4532 | INPPL1 2.4159 | MYO9B 2.3989 | PDLIM2 2.3613 | HMCN1 2.3535 | LASP1 2.3015 | SEPT2 2.2728 | SEPT5 2.2712 | FGF1 2.2613 | PARD6A 2.2550 | CALD1 2.2528 | RAI14 2.2453 | ADD3 2.1906 | ITPR2 2.1594 | SHROOM2 2.1572 | WDPCP 2.1418 | ACTB 2.1337 | OR2C1 2.1162 | PPP1R9A 2.0454 | EXOC3L1 2.0447 | PARD3 2.0430 | ACTN1 2.0386 | TRPV4 2.0262 | NEDD9 1.9952 | PKD2 1.9879 | SNCA 1.9846 | NEDD4 1.9836 | PRKD1 1.9823 | AXIN1 1.9756 | EXOC2 1.9693 | RIC8B 1.9498 | ASPH 1.9379 | MYO6 1.9297 | EXOC4 1.9205 | FER 1.8987 | RHOA 1.8947 | EXOC1 1.8935 | HAMP 1.8819 | CAPZA2 1.8696 | SPTBN4 1.8647 | NDFIP1 1.8539 | DRD4 1.8319 | LAMC2 1.8307 | CAPZA1 1.8250 | DAXX 1.8243 | SEPT12 1.8144 | SEPT3 1.7964 | SEPT6 1.7947 | PRKCZ 1.7929 | CAP1 1.7921 | MYO10 1.7867 | TMOD1 1.7664 | CLASP2 1.7640 | TCHP 1.7599 | DLG4 1.7370 | ACTN2 1.7215 | GYS2 1.7030 | MYO7A 1.7012 | SCIN 1.6737 | ARHGAP32 1.6693 | CLIC5 1.6546 | MARCKS 1.6411 | EXOC6 1.6287 | TRPC4 1.6274 | MYO1A 1.6056 | MARK2 1.6028 | EXOC7 1.5950 | USP2 1.5942 | PARD6B 1.5688 | GYPC 1.5667 | RYR1 1.5561 | FLNB 1.5528 | LLGL1 1.5422 | GIPC1 1.5412 | MAP2K1 1.5376 | MYZAP 1.5274 | MYH2 1.5065 | CNKSR1 1.5044 | CYTIP 1.4988 | MYH10 1.4980 | FERMT2 1.4965 | EPB41L2 1.4914 | SEPT10 1.4658 | CABP1 1.4653 | TRIP10 1.4608 | MYO1F 1.4447 | ACTN4 1.4437 | POTEF 1.4172 | SCNN1A 1.3929 | EPB41 1.3904 | PTK2 1.3822 | AXIN2 1.3665 | MAEA 1.3528 | TSC1 1.3322 | DST 1.3319 | CAPZB 1.3059 | NOS2 1.3024 | DVL2 1.2681 | SPTA1 1.2678 | DVL1 1.2676 | FGB 1.2648 | DSTN 1.2412 | PDZD4 1.1942 | FGA 1.1804 | SELE 1.1773 | NCL 1.1705 | ARF6 1.1563 | WASL 1.1528 | MYH9 1.1496 | ANLN 1.1428 | EZR 1.1330 | PTK2B 1.1280 | ARHGEF7 1.1278 | TRAF6 1.1053 | MAPRE1 1.0809 | GLRX3 1.0767 | NRBP1 1.0691 | SPTB 1.0618 | TRAF2 1.0448 | PSEN1 1.0274 | TLE6 1.0207 | PXN 1.0115 | CLASP1 0.9995 | SLC4A1 0.9918 | CORO1A 0.9727 | CTGF 0.9616 | SHROOM4 0.9493 | ACTR2 0.9488 | RAB3IP 0.9465 | PRKCI 0.9445 | GPSM2 0.9440 | FLNA 0.9266 | EXOC6B 0.9161 | SEPT8 0.8694 | DBNL 0.8579 | FGG 0.8458 | SPINK5 0.8454 | PAFAH1B1 0.8148 | LANCL2 0.7974 | ARFIP2 0.7918 | DVL3 0.7715 | FMNL1 0.7139 | DIXDC1 0.6947 | ITCH 0.6286 | EXOC8 0.6238 | CTNNB1 0.5466 | FBLIM1 0.5285 | SPRR4 0.5045 | FABP2 0.4716 | SEPT1 0.4455 | CAPZA3 0.2266 | DKFZp586I031 | ECAT1 | |||||||||||||||||||||||||||||
euchromatin (boxplot) | 12 | 12 | 2.843364368497332 | 0.0022320002259453853 | 0.03734778460263408 | 0.01718213058419244 | SIRT1 7.4176 | DNMT3A 3.2888 | CECR2 2.9058 | SMARCA4 2.7826 | JUN 1.8868 | NR1H4 1.4113 | TBP 1.2915 | TRIM28 1.2663 | CBX3 1.1599 | TRIM24 1.0739 | RBMX 0.7659 | CREB1 0.5390 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
negative regulation of response to DNA damage stimulus (boxplot) | 16 | 16 | 2.84020295484758 | 0.002254241990052752 | 0.037591216257330196 | 0.017123287671232876 | SIRT1 7.4176 | SNAI2 2.6919 | KDM1A 2.5909 | HMGA2 2.5708 | CD44 2.4166 | MIF 2.1324 | TWIST1 2.0979 | WNT1 2.0180 | DYRK1A 1.6138 | SNAI1 1.3990 | PSMD10 1.2562 | RPS3 1.1846 | PARPBP 1.1212 | CD74 1.0390 | RNF169 0.8308 | MDM2 0.7327 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proteoglycan biosynthetic process (boxplot) | 33 | 33 | 2.835258039332697 | 0.0022894342659667277 | 0.038048217086780384 | 0.020477815699658702 | CHST11 4.7693 | HS6ST1 3.0605 | XYLT1 2.9735 | HS3ST3B1 2.9193 | NDST4 2.6162 | CHST8 2.5435 | CSGALNACT1 2.5188 | ACAN 2.4524 | GAL3ST4 2.3305 | CHSY1 2.3303 | CHST9 2.2782 | EXT1 2.2085 | NDST2 2.1818 | DSE 2.0810 | EXT2 1.9834 | NDST1 1.9496 | CHST13 1.8760 | CHST3 1.8576 | CHST7 1.6567 | IGF1 1.6014 | CHST12 1.5776 | B3GALT6 1.4593 | FOXL1 1.4158 | EXTL3 1.3288 | SLC35D1 1.2687 | CYTL1 1.2397 | GLCE 1.2015 | HS2ST1 1.1877 | GAL3ST3 1.0039 | CSGALNACT2 0.9653 | NDST3 0.9068 | EXTL2 0.8726 | HS3ST5 0.5510 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cell envelope (boxplot) | 17 | 17 | 2.829430467413156 | 0.0023315465773879884 | 0.038616734159721056 | 0.02040816326530612 | GRID1 5.7829 | GRIA4 3.3765 | GRIN3A 3.1467 | GRID2 3.0003 | GRIN2B 2.2951 | GRIN2A 2.0931 | GRIN2C 1.9757 | P2RX1 1.9501 | GRIK1 1.8243 | SLC11A1 1.7405 | GRIN2D 1.3766 | GRIN1 1.2637 | TDGF1P3 1.2115 | GRIA1 1.1475 | GRIN3B 1.0627 | GRIA2 0.9514 | DAG1 0.6937 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
external encapsulating structure part (boxplot) | 17 | 17 | 2.829430467413156 | 0.0023315465773879884 | 0.038616734159721056 | 0.02040816326530612 | GRID1 5.7829 | GRIA4 3.3765 | GRIN3A 3.1467 | GRID2 3.0003 | GRIN2B 2.2951 | GRIN2A 2.0931 | GRIN2C 1.9757 | P2RX1 1.9501 | GRIK1 1.8243 | SLC11A1 1.7405 | GRIN2D 1.3766 | GRIN1 1.2637 | TDGF1P3 1.2115 | GRIA1 1.1475 | GRIN3B 1.0627 | GRIA2 0.9514 | DAG1 0.6937 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
mast cell mediated immunity (boxplot) | 11 | 11 | 2.8284254638068687 | 0.002338879626841317 | 0.038616734159721056 | 0.02027027027027027 | ADORA3 4.1949 | CPLX2 3.2544 | LAT 2.8728 | PIK3CD 2.5941 | PIK3CG 2.5697 | SERPINB9 2.0797 | YWHAZ 1.7916 | LYN 1.5986 | LAT2 1.3653 | S100A13 1.3048 | MILR1 0.2667 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
detection of mechanical stimulus (boxplot) | 21 | 21 | 2.8230945097710287 | 0.0023781274303487088 | 0.038991713505650304 | 0.020202020202020204 | GPR98 4.6366 | FYN 3.7055 | PCDH15 3.5572 | TCAP 3.2295 | ASIC2 2.7474 | GRIN2B 2.2951 | CHRNA10 2.0484 | PKD2 1.9879 | MYC 1.9575 | JUP 1.9019 | HPN 1.7202 | IL18 1.7039 | SERPINE2 1.6272 | TRPA1 1.5544 | MKKS 1.5151 | CHRNA9 1.5108 | COL11A1 1.4339 | SLC12A2 0.9968 | PKD1 0.8841 | SOX2 0.5800 | STRC 0.4507 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
vascular process in circulatory system (boxplot) | 77 | 78 | 2.816252931999778 | 0.0024293699028188342 | 0.03969866670626363 | 0.020134228187919462 | CAV1 3.7656 | PDE2A 3.7330 | ACTA2 3.1316 | GCLM 3.0852 | VEGFA 3.0488 | VEGFB 2.9601 | SLIT2 2.8500 | ADRA1D 2.6991 | ITGA1 2.5638 | GUCY1A3 2.4867 | PLOD3 2.4686 | YES1 2.4165 | BDKRB2 2.4033 | SERPINF2 2.4022 | PDE3A 2.3821 | EDN1 2.3459 | ADORA2B 2.3294 | SLC6A4 2.2725 | AGT 2.2659 | HBB 2.2562 | GCLC 2.2372 | AGTR2 2.2307 | KEL 2.2280 | AMOT 2.2199 | NR3C1 2.0926 | P2RX1 1.9501 | HTR2B 1.9303 | AGTR1 1.9300 | AVP 1.9195 | AZU1 1.9033 | GPX1 1.8947 | EDN2 1.8797 | TEK 1.8630 | EDNRB 1.7889 | ADM 1.7485 | KNG1 1.7229 | MYLK3 1.7219 | ADORA1 1.7070 | IL18 1.7039 | NOS3 1.6288 | ADRB1 1.6047 | CBS 1.6003 | SRC 1.5906 | ARHGAP35 1.5865 | PTPRJ 1.5709 | NPPC 1.5320 | P2RX4 1.5095 | ADRA1B 1.4817 | GCH1 1.4425 | APOE 1.4398 | FGFBP3 1.4193 | FOXC2 1.4158 | NTS 1.3859 | CFTR 1.3770 | NPR1 1.3340 | ATG5 1.3205 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | FOXC1 1.2136 | FOXS1 1.1734 | KCNJ8 1.1442 | ANGPT1 1.1416 | SOD2 1.1214 | PDE5A 1.1185 | EDN3 1.1118 | NPPA 1.0642 | NPPB | CALCB 1.0599 | ADRB2 1.0467 | CTNNBIP1 0.9627 | RAMP2 0.9523 | RGS2 0.9397 | PIK3C2A 0.8669 | SOD1 0.8543 | CALCA 0.8098 | EDNRA 0.8058 | ACE 0.7753 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
triglyceride biosynthetic process (boxplot) | 41 | 41 | 2.8162083596945644 | 0.002429706993483105 | 0.03969866670626363 | 0.020066889632107024 | LPIN2 5.2136 | LPCAT1 3.0227 | ELOVL6 2.9754 | GPD1 2.7351 | ACLY 2.7017 | AGPAT4 2.5633 | GPAT2 2.5064 | ELOVL2 2.4805 | MOGAT3 2.4686 | PCK1 2.3007 | ACSL1 2.2283 | LPIN1 2.1486 | ELOVL1 2.0817 | ACSL5 2.0627 | AGPAT6 2.0214 | AGPAT2 2.0126 | LPL 1.9485 | ELOVL7 1.9273 | MOGAT1 1.9020 | SLC25A1 1.8029 | AGPAT3 1.7230 | GK 1.7138 | DGAT1 1.7111 | ACSL6 1.6845 | AGPAT5 1.6333 | PNPLA3 1.6241 | ACSL3 1.6086 | AGPAT1 1.5913 | HSD17B12 1.5489 | TECR 1.5086 | GPAM 1.4378 | DGAT2 1.4198 | ACSL4 1.2837 | FASN 1.1849 | ELOVL4 1.1167 | GPD1L 1.0398 | MOGAT2 0.9999 | ELOVL5 0.8407 | ACACA 0.8142 | AGPAT9 0.6685 | ELOVL3 0.6419 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nucleoside binding (boxplot) | 15 | 15 | 2.815299932318016 | 0.002436586458890666 | 0.03969866670626363 | 0.02 | POLA1 6.3131 | SLC28A1 2.8837 | CDA 2.8624 | PNP 2.7166 | SLC28A3 2.0301 | POLR3B 1.9387 | POLR3A 1.9173 | ADORA1 1.7070 | C6orf130 1.5236 | ACTN4 1.4437 | DCK 1.4347 | ADA 1.4333 | POLR2B 1.3262 | SLC28A2 1.0299 | POLR1B 0.6651 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cell-matrix adhesion (boxplot) | 96 | 97 | 2.814036560420283 | 0.0024461831925183253 | 0.03969866670626363 | 0.019933554817275746 | TNN 4.2700 | ITGBL1 3.7597 | C22orf28 3.4290 | TAOK2 3.3686 | FBLN5 3.1469 | ACTN3 3.1352 | PPFIA1 3.0455 | COL13A1 2.7836 | TRPM7 2.7626 | PTPRK 2.7450 | PARVG 2.7255 | ITGA2 2.6856 | JAM3 2.6353 | FREM1 2.6344 | ITGA1 2.5638 | MUC4 2.5381 | ITGB2 2.5057 | CD44 2.4166 | SIGLEC1 2.3633 | LAMA5 2.3426 | DLC1 2.2963 | CNTN2 2.2820 | HPSE 2.2717 | AGT 2.2659 | ARHGAP6 2.1854 | BCL2 2.1766 | ITGB3 2.1729 | PIP5K1A 2.0835 | ITGB5 2.0784 | NPNT 2.0460 | NID1 2.0430 | ACTN1 2.0386 | PPFIA2 2.0377 | ITGA10 2.0120 | ITGA8 1.9537 | RAPH1 1.9311 | ITGB6 1.9218 | RAC1 1.9125 | RHOA 1.8947 | SNED1 1.8800 | VTN 1.8442 | THBS3 1.8194 | LYVE1 1.7915 | ADAM15 1.7569 | ITGAD 1.7565 | ITGAV 1.7509 | ACTN2 1.7215 | ITGA11 1.7210 | VCL 1.7125 | EDA 1.6572 | SORBS1 1.6523 | DDR1 1.6458 | NID2 1.5906 | TESK2 1.5784 | CDK5 1.5715 | ITGA2B 1.5355 | COL3A1 1.4690 | COL17A1 1.4533 | PDPK1 1.4292 | TMEM8B 1.4208 | ANGPTL3 1.4147 | TRIP6 1.3664 | AJUBA 1.3552 | COL5A3 1.3492 | TSC1 1.3322 | ITGA3 1.3270 | ADAM9 1.3137 | CCL21 1.2605 | BCL2L11 1.2301 | GP5 1.2192 | ITGB7 1.1840 | SRF 1.1778 | TECTA 1.1635 | SGCE 1.1407 | ILK 1.1347 | ITGA7 1.1296 | PTK2B 1.1280 | ITGB1 1.1192 | HOXD3 1.0955 | PXN 1.0115 | ADAMTS13 1.0115 | CTGF 0.9616 | EPDR1 0.9433 | CD34 0.9161 | ITGB4 0.8918 | PKD1 0.8841 | ITGB8 0.8819 | BCAM 0.8765 | ITGA6 0.8763 | FXC1 0.7918 | ECM2 0.7676 | DAG1 0.6937 | DEFB118 0.6419 | THY1 0.6002 | ITGB1BP1 0.5811 | CTNNB1 0.5466 | UCC1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
clathrin binding (boxplot) | 11 | 11 | 2.805609610577875 | 0.002511074854874673 | 0.040492117956823934 | 0.019867549668874173 | PICALM 3.8576 | HIP1 3.4696 | NCALD 3.4326 | SNAP91 2.4483 | DNER 2.1720 | AP2B1 1.9360 | CALY 1.4903 | LDLRAP1 1.4279 | CLINT1 1.4152 | AFTPH 1.1535 | SYT6 1.0354 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cyclic nucleotide binding (boxplot) | 29 | 29 | 2.8053636940797566 | 0.002512991690751143 | 0.040492117956823934 | 0.019801980198019802 | PDE2A 3.7330 | PDE10A 3.5081 | PDE11A 2.9328 | PDE4D 2.8834 | RAPGEF3 2.6418 | CNGB1 2.5546 | CNGB3 2.5426 | PRKG1 2.4878 | PDE3A 2.3821 | HCN1 2.2865 | PDE6C 2.2565 | PDE1C 2.1963 | PRKAR1B 2.1387 | HCN2 2.0858 | CNGA2 1.8158 | PRKAR2B 1.7791 | PDE3B 1.7081 | RAPGEF4 1.6971 | HCN4 1.5579 | PDE6H 1.3989 | PRKAR1A 1.3889 | PRKAR2A 1.3064 | PRKG2 1.2488 | CNGA3 1.1275 | PDE5A 1.1185 | PDE6G 1.0776 | CNGA4 0.8741 | HCN3 0.8529 | CNGA1 0.4993 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
proteoglycan binding (boxplot) | 15 | 15 | 2.8004913137756176 | 0.002551244033941691 | 0.04087009295029213 | 0.019736842105263157 | GPC5 3.7774 | SLIT1 3.2641 | SLIT2 2.8500 | GPC6 2.6963 | FST 2.4000 | GPC2 2.3305 | CECR1 2.2636 | COL5A1 1.9082 | GPC3 1.8708 | HRG 1.8045 | GPC1 1.4900 | PTPRC 1.4182 | GPC4 1.3712 | COMP 1.0103 | THBS1 0.7292 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
negative regulation of developmental growth (boxplot) | 21 | 21 | 2.800097791246784 | 0.0025543563745151765 | 0.04087009295029213 | 0.019672131147540985 | DCC 5.1066 | SLIT1 3.2641 | TNR 3.0413 | MSTN 2.6651 | MT3 2.3391 | BCL11A 2.3352 | RTN4 2.3237 | SPP1 2.1654 | WNT3 2.0876 | RNF6 1.9069 | RYK 1.6892 | SEMA3A 1.6808 | WNT3A 1.6407 | FGFR3 1.4587 | WNT5A 1.3655 | SEMA3F 1.2271 | SEMA4F 1.2167 | GSK3A 1.2130 | NTN1 1.2089 | BMP4 1.1081 | ULK1 0.9247 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sterol transporter activity (boxplot) | 14 | 14 | 2.7907901662408934 | 0.0026289773605507882 | 0.04184098822036206 | 0.0196078431372549 | ABCA1 5.6064 | STARD3 3.2295 | APOA1 3.0248 | APOA4 2.5911 | ABCG4 2.1882 | ABCG1 2.0741 | CETP 1.6214 | ABCG5 1.4958 | ABCG8 1.4958 | STAR 1.4812 | APOE 1.4398 | APOB 1.2451 | NPC1 0.9459 | APOA2 0.8951 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
skeletal muscle tissue development (boxplot) | 103 | 106 | 2.790721487733196 | 0.002629535212728129 | 0.04184098822036206 | 0.019543973941368076 | GPHN 5.9364 | CAV1 3.7656 | DMD 3.6492 | PAX7 3.3979 | ERBB2 3.2295 | FOXP2 3.2196 | ADAM12 3.1898 | MBNL1 2.8792 | METTL8 2.8193 | CAV2 2.8160 | CHAT 2.7603 | RXRG 2.6680 | MUSK 2.5943 | COL4A1 2.5872 | KCNH1 2.5742 | CACNA1H 2.4410 | FOXP1 2.3270 | CDON 2.3231 | COL19A1 2.3157 | NOS1 2.3035 | CACNB2 2.2123 | VGLL2 2.2100 | HOMER1 2.1943 | SKI 2.1799 | DNER 2.1720 | LRP4 2.1606 | FOXL2 2.1573 | APP 2.1303 | PDZRN3 2.0541 | MEF2C 2.0426 | WNT1 2.0180 | WNT10B | MYF5 1.9843 | MYF6 | NR2F2 1.9601 | MYL6 1.9522 | MYL6B 1.9522 | CTSB 1.9372 | TNC 1.9083 | GPX1 1.8947 | RHOA | MYL3 1.8709 | MEGF10 1.8707 | AFG3L2 1.8657 | HLX 1.8571 | RCAN1 1.8416 | BARX2 1.8319 | HOXD10 1.8126 | HOXD9 1.8126 | CHRND 1.7516 | MSC 1.7327 | CASQ1 1.6978 | MYEF2 1.6778 | IGF1 1.6014 | MYOG 1.5902 | LRRK2 1.5730 | CDK5 1.5715 | RYR1 1.5561 | FOXP3 1.5343 | KIAA1161 1.5218 | NPHS1 1.4983 | LAMB2 1.4979 | EP300 1.4888 | SIN3B 1.4758 | F2R 1.4291 | PPP3CA 1.4235 | DNAJA3 1.4206 | SVIL 1.3995 | CACNA1S 1.3954 | CAPN2 1.3921 | CACNG2 1.3692 | IGFBP5 1.3648 | ALS2 1.3539 | CHRNA1 1.3109 | COL4A5 1.3070 | NF1 1.2913 | MYOD1 1.2690 | DVL1 1.2676 | SHH 1.2438 | DOK7 1.2147 | SRPK3 1.1942 | MYH9 1.1496 | MET 1.1441 | SORT1 1.1418 | DYRK1B 1.1007 | MYLK2 1.0997 | TAZ 1.0762 | TCF21 1.0756 | LEMD2 1.0653 | ERBB3 1.0409 | NRD1 1.0284 | DCN 1.0126 | ZNF238 1.0112 | CSRP3 1.0035 | PITX1 0.9816 | ACTA1 0.9736 | MAPK14 0.9700 | MEOX2 0.9481 | VAMP5 0.9005 | SIX1 0.8071 | SKIL 0.7578 | AVPR1A 0.6808 | SNTA1 0.5644 | SIX4 0.4859 | MYLPF 0.4455 | IGSF8 0.4340 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
symporter activity (boxplot) | 129 | 132 | 2.790292195758667 | 0.0026330246294110626 | 0.04184098822036206 | 0.01948051948051948 | SLC12A8 4.6192 | SLC4A4 3.5728 | SLC16A5 3.4358 | SLC12A3 3.4276 | SLC20A2 3.3941 | SLC4A10 3.3903 | SLC16A6 3.3452 | SLC45A1 3.2846 | SLC12A6 3.1445 | SLC25A18 2.9058 | SLC28A1 2.8837 | SLC46A2 2.7690 | SLC16A12 2.6720 | SLC6A16 2.5905 | SLC12A5 2.5026 | SLC1A6 2.4978 | SLC5A1 2.4893 | SLC6A17 2.4874 | SLC24A3 2.4609 | SLC6A14 2.4496 | SLC34A1 2.4197 | SLC12A7 2.4107 | SLC10A2 2.3315 | SLC12A1 2.3097 | SLC4A11 2.3045 | SLC6A4 2.2725 | SLC2A10 2.1966 | SLC1A3 2.1895 | SLC23A2 2.1821 | SLC17A1 2.1754 | SLC17A4 2.1754 | SLC6A19 2.1703 | SLC12A4 2.1598 | SLC6A7 2.1496 | SLC38A1 2.1315 | SLC13A1 2.1045 | SLC5A4 2.0750 | SLC28A3 2.0301 | SLC1A1 2.0244 | SLC17A8 2.0171 | SLC36A4 1.9944 | SLC25A3 1.9902 | SLC22A4 1.9862 | SLC24A4 1.9794 | SLC22A5 1.9715 | SLC24A2 1.9291 | SLC17A6 1.8970 | SLC16A1 1.8765 | SLC1A7 1.8763 | SLC5A7 1.8496 | SLC6A20 1.7941 | SLC5A12 1.7822 | SLC1A2 1.7777 | SLC24A1 1.7667 | SLC17A7 1.7655 | SLC6A12 1.7455 | SLC5A3 1.7426 | SLC16A14 1.7303 | SLC1A4 1.7165 | SLC5A5 1.7140 | SLC16A4 1.7138 | SLC10A3 1.7129 | SLC15A1 1.7121 | SLC6A9 1.6970 | SLC6A6 1.6945 | SLC35A1 1.6916 | SLC24A5 1.6778 | SLC6A5 1.6321 | SLC32A1 1.6305 | SLC13A5 1.6232 | SLC6A18 1.6149 | SLC15A4 1.6042 | SLC15A2 1.5812 | SLC38A2 1.5792 | SLC5A11 1.5783 | SLC10A7 1.5716 | SLC16A9 1.5632 | SLC6A11 1.5526 | SLC10A6 1.5351 | SLC17A5 1.5144 | SLC13A4 1.5077 | SLC4A7 1.4843 | SLC6A1 1.4647 | SLC12A9 1.4218 | SLC16A8 1.3992 | SLC13A3 1.3874 | SLC36A1 1.3805 | SLC17A3 1.3665 | SLC2A9 1.3637 | SLC25A22 1.3307 | SLC11A2 1.3019 | SLC35A4 1.2937 | SLC16A11 1.2737 | SLC16A13 | ZAR1L 1.2706 | SLC6A2 1.2651 | SLC23A1 1.2468 | SLC38A4 1.2276 | SLC5A8 1.2152 | SLC22A18 1.2109 | SLC4A5 1.2031 | SLC6A3 1.1970 | SLC17A2 1.1695 | SLC10A5 1.1622 | SLC36A2 1.0881 | SLC15A3 1.0627 | SLC13A2 1.0382 | SLC28A2 1.0299 | SLC6A13 1.0084 | SLC12A2 0.9968 | SLC34A3 0.9856 | SLC34A2 0.9793 | SLC35A5 0.9316 | SLC16A7 0.9267 | SLC16A2 0.8935 | SLC1A5 0.8929 | SLC5A6 0.8757 | SLC15A5 0.8485 | SLC35A2 0.7749 | SLC6A15 0.7607 | SLC16A3 0.7256 | SLC6A8 0.7171 | SLC20A1 0.6624 | SLC10A4 0.6477 | ZAR1 0.5468 | SLC5A2 0.4536 | SLC38A3 0.4134 | SLC10A1 0.4129 | SLC35A3 0.4014 | C2orf18 0.2337 | NAGLT1 | SMVT | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
acylglycerol biosynthetic process (boxplot) | 46 | 46 | 2.788070226085556 | 0.0026511524221206617 | 0.04184098822036206 | 0.019417475728155338 | LPIN2 5.2136 | LPCAT1 3.0227 | ELOVL6 2.9754 | GPD1 2.7351 | ACLY 2.7017 | AGPAT4 2.5633 | GPAT2 2.5064 | ELOVL2 2.4805 | MOGAT3 2.4686 | PCK1 2.3007 | ACSL1 2.2283 | LCLAT1 2.1535 | LPIN1 2.1486 | ELOVL1 2.0817 | ACSL5 2.0627 | AGPAT6 2.0214 | AGPAT2 2.0126 | PLCE1 2.0072 | LPL 1.9485 | ELOVL7 1.9273 | MOGAT1 1.9020 | SLC25A1 1.8029 | AGPAT3 1.7230 | GK 1.7138 | DGAT1 1.7111 | ACSL6 1.6845 | ANG 1.6605 | AGPAT5 1.6333 | PNPLA3 1.6241 | ACSL3 1.6086 | CDS2 1.6034 | AGPAT1 1.5913 | HSD17B12 1.5489 | TECR 1.5086 | GPAM 1.4378 | DGAT2 1.4198 | ACSL4 1.2837 | FASN 1.1849 | ELOVL4 1.1167 | GPD1L 1.0398 | CDS1 1.0042 | MOGAT2 0.9999 | ELOVL5 0.8407 | ACACA 0.8142 | AGPAT9 0.6685 | ELOVL3 0.6419 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
neutral lipid biosynthetic process (boxplot) | 46 | 46 | 2.788070226085556 | 0.0026511524221206617 | 0.04184098822036206 | 0.019417475728155338 | LPIN2 5.2136 | LPCAT1 3.0227 | ELOVL6 2.9754 | GPD1 2.7351 | ACLY 2.7017 | AGPAT4 2.5633 | GPAT2 2.5064 | ELOVL2 2.4805 | MOGAT3 2.4686 | PCK1 2.3007 | ACSL1 2.2283 | LCLAT1 2.1535 | LPIN1 2.1486 | ELOVL1 2.0817 | ACSL5 2.0627 | AGPAT6 2.0214 | AGPAT2 2.0126 | PLCE1 2.0072 | LPL 1.9485 | ELOVL7 1.9273 | MOGAT1 1.9020 | SLC25A1 1.8029 | AGPAT3 1.7230 | GK 1.7138 | DGAT1 1.7111 | ACSL6 1.6845 | ANG 1.6605 | AGPAT5 1.6333 | PNPLA3 1.6241 | ACSL3 1.6086 | CDS2 1.6034 | AGPAT1 1.5913 | HSD17B12 1.5489 | TECR 1.5086 | GPAM 1.4378 | DGAT2 1.4198 | ACSL4 1.2837 | FASN 1.1849 | ELOVL4 1.1167 | GPD1L 1.0398 | CDS1 1.0042 | MOGAT2 0.9999 | ELOVL5 0.8407 | ACACA 0.8142 | AGPAT9 0.6685 | ELOVL3 0.6419 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
protein ADP-ribosylation (boxplot) | 22 | 24 | 2.7818213606540625 | 0.0027027392371946624 | 0.04232558946452923 | 0.01929260450160772 | SIRT1 7.4176 | TIPARP 3.3907 | TNKS2 2.2784 | ART4 2.2287 | SIRT2 2.1358 | GNA14 2.0910 | SIRT6 2.0739 | ART1 2.0484 | ART5 | PARP4 1.9415 | GNA15 1.8776 | PARP1 1.8367 | TNKS 1.7942 | GNAQ 1.7558 | ART3 1.6775 | TRIM23 1.4374 | PARP3 1.3621 | GNA11 1.3379 | PARP10 1.3309 | SIRT3 0.9975 | SIRT4 0.9183 | PARP2 0.9028 | SIRT5 0.8488 | DO | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of cellular catabolic process (boxplot) | 88 | 88 | 2.779052465427014 | 0.0027258859456684714 | 0.04255168923493978 | 0.019230769230769232 | SIRT1 7.4176 | ARHGEF10 3.8915 | FABP1 3.5813 | ZFP36 3.4715 | FURIN 3.4013 | MLXIPL 3.3990 | SUMO2 3.2421 | INSR 3.1624 | TNF 3.0639 | SOCS5 3.0169 | GNB2L1 3.0025 | APOA4 2.5911 | APOA5 2.5911 | ABHD5 2.5629 | GCLC 2.2372 | AKT1 2.1144 | TWIST1 2.0979 | PACSIN3 2.0740 | PNPT1 2.0485 | SH3D19 2.0408 | PRICKLE1 2.0282 | CSNK1E 2.0081 | GTPBP1 1.9779 | AXIN1 1.9756 | INS 1.9742 | IRS1 1.9115 | IL1B 1.8813 | PRKAA2 1.8703 | IRS2 1.8084 | RNF180 1.7893 | FBXO22 1.7795 | AKT2 1.7769 | DNAJB2 1.7755 | PNPLA2 1.7743 | TP53INP1 1.7689 | UBE2V2 1.7203 | UVRAG 1.7127 | HSPBP1 1.7013 | ABCD2 1.6687 | TAF1 1.6628 | HIF1A 1.6618 | RCHY1 1.6184 | IGF1 1.6014 | ARNT 1.5773 | LRRK2 1.5730 | TRIB1 1.5670 | TRIB2 1.5323 | NUB1 1.5179 | ADAM8 1.5178 | VCP 1.4995 | PHKG2 1.4975 | ADRA1B 1.4817 | SMAD7 1.4674 | DAB2 1.4589 | USP5 1.4575 | APOE 1.4398 | PLK1 1.4034 | PTEN 1.3846 | TRIM13 1.3589 | APOC2 1.3441 | MTDH 1.3350 | BTG2 1.3309 | ADAM9 1.3137 | SUPV3L1 1.2808 | PSMD10 1.2562 | CLU 1.2550 | CPT1A 1.1834 | ADRA2A 1.1742 | PLK3 1.1387 | BECN1 1.1091 | GPLD1 1.0747 | STUB1 1.0527 | NRD1 1.0284 | PSEN1 1.0274 | PPARA 1.0266 | PRKCD 1.0164 | ATG14 1.0125 | AADAC 0.9668 | PIK3CB 0.9249 | ULK1 0.9247 | IFNG 0.8931 | GAPDHS 0.7934 | PIM2 0.7749 | TP53INP2 0.7727 | PRKAA1 0.7726 | MDM2 0.7327 | CSNK1D 0.7256 | SUMO1 0.5499 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
extrinsic to membrane (boxplot) | 119 | 123 | 2.776503031435425 | 0.0027473561327445717 | 0.04275026135219738 | 0.019169329073482427 | CDH2 3.9744 | RGS7 3.8772 | GNAO1 3.7443 | CNR2 3.3995 | ST14 3.3519 | NF2 3.2554 | GHR 3.1211 | FES 3.1088 | GNAL 3.0690 | CUBN 2.9709 | PRNP 2.8953 | GNG7 2.8840 | CAV2 2.8160 | SYNJ2 2.7782 | GFRA1 2.6490 | GNB5 2.5477 | GML 2.5090 | FRMD5 2.4849 | SNX5 2.4768 | APC2 2.3743 | GNA12 2.3370 | EPB41L3 2.3227 | FARP1 2.2734 | FARP2 2.2728 | SYTL2 2.2517 | EPB41L4A 2.1720 | GNB1 2.1617 | RGS9 2.1474 | PLAUR 2.1054 | GNA14 2.0910 | GNG4 2.0405 | FRMD3 2.0354 | GNG12 2.0311 | CNTFR 2.0310 | MFGE8 2.0138 | RGS11 1.9756 | EEA1 1.9640 | SYTL3 1.9442 | JUP 1.9019 | TAMM41 1.9009 | FER 1.8987 | FOLR3 1.8889 | SCUBE1 1.8842 | GNA15 1.8776 | USP8 1.8114 | TDGF1 1.8065 | TGM3 1.8046 | GNG2 1.7642 | RGS6 1.7571 | GNAQ 1.7558 | DLG4 1.7370 | EPB41L4B 1.7269 | SNX10 1.6960 | MYLIP 1.6924 | BST1 1.6663 | RPH3A 1.6628 | GNAI1 1.6302 | SERPINE2 1.6272 | HIST1H2BA 1.6112 | GNA13 1.6039 | ARRB1 1.5906 | SNX9 1.5729 | PVRL1 1.5566 | MYZAP 1.5274 | GNAT2 1.5269 | ERRFI1 1.5159 | SYTL1 1.5004 | EPB41L2 1.4914 | NOA1 1.4875 | PCSK9 1.4808 | HCK 1.4790 | SMAD7 1.4674 | GNG13 1.4664 | GNAI3 1.4435 | JAKMIP1 1.4415 | APOE 1.4398 | DNAJA3 1.4206 | DMBT1 1.4123 | ANXA2 1.4037 | EPB41 1.3904 | WDFY3 1.3854 | S100A6 1.3742 | RGS19 1.3726 | CTNNA1 1.3657 | MUC16 1.3623 | GFRA2 1.3610 | PML 1.3600 | GNA11 1.3379 | PLG 1.3287 | GNG10 1.2228 | GNAT3 1.2161 | CDH1 1.2150 | TDGF1P3 1.2115 | SOX10 1.2019 | UMOD 1.1937 | GNAS 1.1857 | EPB41L1 1.1815 | EZR 1.1330 | RDX 1.1316 | GNGT2 1.1135 | SNX18 1.0994 | GNG3 1.0530 | NUMB 1.0524 | GNAZ 1.0149 | CYLD 1.0066 | AAK1 0.9958 | SYTL4 0.9559 | GNG11 0.8832 | GNGT1 | EPB41L5 0.8760 | GNG8 0.8371 | S100A10 0.8010 | MSN 0.7412 | SNX16 0.6631 | GFRA3 0.6517 | ANXA2P2 0.6424 | GNAI2 0.5640 | CTNNB1 0.5466 | GNG5 0.5328 | GNAT1 0.4134 | A6NC00 | C20orf7 | DKFZp781H1755 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
negative regulation of lipid storage (boxplot) | 14 | 14 | 2.7760018319714344 | 0.0027515949187477684 | 0.04275026135219738 | 0.01910828025477707 | ABCA1 5.6064 | TNF 3.0639 | ABHD5 2.5629 | NFKBIA 2.3376 | ITGB3 2.1729 | ABCG1 2.0741 | PNPLA2 1.7743 | ITGAV 1.7509 | IL6 1.7153 | PPARG 1.6692 | NR1H3 1.3265 | NR1H2 1.1632 | CRP 1.0506 | PPARA 1.0266 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
endothelial cell development (boxplot) | 21 | 21 | 2.7731106332711923 | 0.0027761620427388944 | 0.04292508778741214 | 0.01904761904761905 | HEG1 4.0972 | PDE2A 3.7330 | HOXA13 2.9921 | PDE4D 2.8834 | SOX18 2.5964 | PLOD3 2.4686 | AGT 2.2659 | ENG 2.2047 | WNT7A 2.0616 | GPX1 1.8947 | WNT7B 1.8583 | GSTM3 1.6461 | F2RL1 1.6183 | NOTCH4 1.5913 | LECT1 1.5203 | CCM2 1.4998 | TNMD 1.3058 | COL18A1 1.2818 | VEZF1 1.1622 | ID1 0.6515 | CTNNB1 0.5466 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of B cell differentiation (boxplot) | 18 | 18 | 2.771235642421571 | 0.0027921998606244003 | 0.04303687229971868 | 0.0189873417721519 | BTK 4.4391 | CD27 4.1635 | INPP5D 3.1650 | CARD11 3.1018 | FLT3 2.7949 | PRDM1 2.3377 | SYK 2.1149 | ID2 1.6791 | BAD 1.6791 | INHBA 1.6220 | STAT5A 1.5114 | PTPRC 1.4182 | SFRP1 1.2842 | IKZF3 1.2788 | NCKAP1L 1.2593 | STAT5B 1.0063 | INHA 0.8631 | NFAM1 0.7992 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
activation of MAPKK activity (boxplot) | 53 | 54 | 2.765486625854995 | 0.002841896784955056 | 0.04366511852607045 | 0.01892744479495268 | CRK 4.9972 | TAOK2 3.3686 | MAP2K2 3.3627 | ERCC6 3.3262 | MAP3K5 3.1884 | MAP3K7 3.1402 | EGFR 2.8090 | HRAS 2.6539 | FLT1 2.6297 | FRS2 2.5419 | TNIK 2.5237 | RAP1A 2.2806 | EGF 2.1937 | KIDINS220 2.0695 | NTRK1 2.0462 | NGF 2.0438 | MAP3K1 1.9924 | BRAF 1.9582 | MAPK1 1.9571 | GADD45B 1.8851 | RAPGEF1 1.8760 | MAPK3 1.8628 | KISS1R 1.7173 | RAF1 1.7090 | ADORA1 1.7070 | MAP3K4 1.6850 | MAP3K10 1.6660 | MAP3K9 1.6641 | GRM1 1.6533 | MAP3K11 1.5775 | LRRK2 1.5730 | MAP2K1 1.5376 | MAP3K6 1.5004 | CARTPT 1.4844 | MAP3K13 1.4769 | F2R 1.4291 | JAK2 1.4043 | GADD45G 1.3775 | ADAM9 1.3137 | CDK1 1.2389 | PLCG1 1.1759 | MAPKBP1 1.1427 | FGF2 1.1278 | TGFBR1 1.1193 | BMP4 1.1081 | YWHAB 1.0405 | PSEN1 1.0274 | KRAS 0.9975 | MAP3K3 0.9421 | NRAS 0.9279 | LAMTOR2 0.8797 | NRK 0.6497 | GNAI2 0.5640 | MLTK | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
asymmetric protein localization (boxplot) | 14 | 14 | 2.762438497957926 | 0.0028685684666589495 | 0.0439367571413656 | 0.018867924528301886 | MPP5 5.2324 | COLQ 2.7875 | SHROOM3 2.7639 | HCN1 2.2865 | SHROOM2 2.1572 | WNT7A 2.0616 | VANGL2 2.0307 | ERBB2IP 1.8381 | CELSR1 1.7341 | GOPC 1.6059 | NAPA 1.4933 | MAL 1.3433 | RDX 1.1316 | RAB14 0.7921 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
filopodium (boxplot) | 51 | 52 | 2.760494519008955 | 0.0028856963206657094 | 0.04406097569616455 | 0.018808777429467086 | CD302 3.7173 | SPATA13 3.6908 | CIB1 3.2990 | NF2 3.2554 | PODXL 2.9223 | BAIAP2 2.7979 | LY6G6D 2.7706 | TIAM2 2.4489 | GPM6A 2.3326 | CXADR 2.1888 | ABI1 2.1356 | MYO3A 2.1330 | FGD4 2.0673 | TWF2 2.0553 | PPP1R9A 2.0454 | RUFY3 2.0308 | MYO1B 2.0278 | TRPV4 2.0262 | PDPN 1.9883 | TWF1 1.9582 | RAPH1 1.9311 | ANTXR1 1.9030 | ENAH 1.8839 | SYNE2 1.8459 | PPP1R9B 1.8018 | MYO10 1.7867 | VIL1 1.7405 | ABI2 1.7385 | ACTN2 1.7215 | PALM 1.7163 | VCAM1 1.7110 | FSCN1 1.6954 | GAP43 1.6161 | CDK5 1.5715 | FAT1 1.5616 | MTM1 1.5088 | SNAP25 1.4539 | ARL4C 1.4383 | VASP 1.3560 | FAM65B 1.2735 | ARF6 1.1563 | EZR 1.1330 | RDX 1.1316 | CDC42 1.0907 | FZD9 1.0715 | ERMN 1.0218 | NGDN 0.9383 | ITGA6 0.8763 | MSN 0.7412 | SLC9A3R1 0.7026 | DAG1 0.6937 | WASH3P | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
embryonic forelimb morphogenesis (boxplot) | 28 | 31 | 2.7601119598343127 | 0.0028890777816726887 | 0.04406097569616455 | 0.01875 | MECOM 4.3913 | NIPBL 3.6793 | HOXA13 2.9921 | HOXA9 2.9921 | CRABP2 2.8723 | TBX3 2.6289 | WNT9A 2.5288 | TWIST1 2.0979 | ALDH1A2 2.0957 | WNT3 2.0876 | LRP6 2.0780 | ALX4 2.0645 | WNT7A 2.0616 | TBX5 1.9756 | HOXD9 1.8126 | RSPO2 1.8089 | OSR2 1.6982 | MSX1 1.4876 | ZNF358 1.4312 | RDH10 1.3839 | RPGRIP1L 1.3825 | SHH 1.2438 | TFAP2A 1.1936 | MSX2 1.0645 | OSR1 0.9759 | EN1 0.9522 | KIAA1715 0.6331 | CTNNB1 0.5466 | EVI1 | LNP | RALDH2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
appendage morphogenesis (boxplot) | 118 | 125 | 2.759701730851647 | 0.0028927077869922435 | 0.04406097569616455 | 0.018691588785046728 | CHST11 4.7693 | MECOM 4.3913 | SALL4 3.8389 | NIPBL 3.6793 | PSEN2 3.3139 | PCSK5 3.2644 | ZBTB16 3.0880 | TP63 3.0850 | HOXA11 2.9921 | HOXA13 | HOXA9 2.9921 | MBNL1 2.8792 | CRABP2 2.8723 | SMARCA4 2.7826 | FGFR2 2.7650 | PBX1 2.6903 | TBX3 2.6289 | WNT9A 2.5288 | SOX9 2.4914 | BMPR1A 2.4359 | ECE1 2.4001 | GNA12 2.3370 | PCNT 2.3313 | GLI3 2.3270 | ACD 2.2550 | AFF3 2.2363 | SKI 2.1799 | LRP5 2.1685 | LRP4 2.1606 | PTCH1 2.1082 | TWIST1 2.0979 | ALDH1A2 2.0957 | WNT3 2.0876 | LRP6 2.0780 | ALX4 2.0645 | WNT7A 2.0616 | LMBR1 2.0526 | PLXNA2 2.0455 | FGF4 2.0087 | TBX5 1.9756 | TULP3 1.9626 | ASPH 1.9379 | BMPR1B 1.9013 | FGF9 1.8959 | GPC3 1.8708 | EVX2 1.8126 | HOXD10 | HOXD11 | HOXD13 | HOXD9 1.8126 | RSPO2 1.8089 | MUSTN1 1.7901 | SP9 1.7865 | GNAQ 1.7558 | CYP26B1 1.7548 | LEF1 1.7470 | CREBBP 1.7131 | OSR2 1.6982 | GJA5 1.6874 | NOTCH1 1.6712 | GREM1 1.6695 | HNF1A 1.6105 | SOX11 1.6081 | PBX2 1.5913 | BMP7 1.5842 | FGFR1 1.5730 | TBX4 1.5316 | GJA1 1.5265 | IFT52 1.5182 | MSX1 1.4876 | DICER1 1.4798 | FLVCR1 1.4767 | FBXW4 1.4676 | MMP13 1.4661 | IDUA 1.4573 | ZNF358 1.4312 | FOXL1 1.4158 | RDH10 1.3839 | NOTCH2 1.3830 | RPGRIP1L 1.3825 | WNT5A 1.3655 | SALL3 1.3649 | GLI2 1.3606 | IFT122 1.3452 | COL2A1 1.3191 | PRRX1 1.2712 | SHH 1.2438 | IMPAD1 1.2243 | HAND2 1.1943 | TFAP2A 1.1936 | GNAS 1.1857 | RARG 1.1840 | SEMA3C 1.1792 | SALL1 1.1703 | RAB23 1.1331 | PRRX2 1.1307 | BMP4 1.1081 | MED1 1.0961 | MSX2 1.0645 | PSEN1 1.0274 | CHD7 1.0210 | PITX1 0.9816 | OSR1 0.9759 | GAS1 0.9741 | FBN2 0.9552 | EN1 0.9522 | SP8 0.9512 | HDAC2 0.9044 | DLX6 0.8896 | IFT88 0.8853 | DLX5 0.8523 | SOX4 0.8314 | HDAC1 0.8048 | KRTAP21-2 0.7966 | BAK1 0.7850 | SFRP2 0.7657 | TFAP2B 0.7079 | FGF10 0.7055 | NOG 0.6617 | KIAA1715 0.6331 | GDF5 0.6266 | CTNNB1 0.5466 | EVI1 | LNP | RALDH2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
limb morphogenesis (boxplot) | 118 | 125 | 2.759701730851647 | 0.0028927077869922435 | 0.04406097569616455 | 0.018691588785046728 | CHST11 4.7693 | MECOM 4.3913 | SALL4 3.8389 | NIPBL 3.6793 | PSEN2 3.3139 | PCSK5 3.2644 | ZBTB16 3.0880 | TP63 3.0850 | HOXA11 2.9921 | HOXA13 | HOXA9 2.9921 | MBNL1 2.8792 | CRABP2 2.8723 | SMARCA4 2.7826 | FGFR2 2.7650 | PBX1 2.6903 | TBX3 2.6289 | WNT9A 2.5288 | SOX9 2.4914 | BMPR1A 2.4359 | ECE1 2.4001 | GNA12 2.3370 | PCNT 2.3313 | GLI3 2.3270 | ACD 2.2550 | AFF3 2.2363 | SKI 2.1799 | LRP5 2.1685 | LRP4 2.1606 | PTCH1 2.1082 | TWIST1 2.0979 | ALDH1A2 2.0957 | WNT3 2.0876 | LRP6 2.0780 | ALX4 2.0645 | WNT7A 2.0616 | LMBR1 2.0526 | PLXNA2 2.0455 | FGF4 2.0087 | TBX5 1.9756 | TULP3 1.9626 | ASPH 1.9379 | BMPR1B 1.9013 | FGF9 1.8959 | GPC3 1.8708 | EVX2 1.8126 | HOXD10 | HOXD11 | HOXD13 | HOXD9 1.8126 | RSPO2 1.8089 | MUSTN1 1.7901 | SP9 1.7865 | GNAQ 1.7558 | CYP26B1 1.7548 | LEF1 1.7470 | CREBBP 1.7131 | OSR2 1.6982 | GJA5 1.6874 | NOTCH1 1.6712 | GREM1 1.6695 | HNF1A 1.6105 | SOX11 1.6081 | PBX2 1.5913 | BMP7 1.5842 | FGFR1 1.5730 | TBX4 1.5316 | GJA1 1.5265 | IFT52 1.5182 | MSX1 1.4876 | DICER1 1.4798 | FLVCR1 1.4767 | FBXW4 1.4676 | MMP13 1.4661 | IDUA 1.4573 | ZNF358 1.4312 | FOXL1 1.4158 | RDH10 1.3839 | NOTCH2 1.3830 | RPGRIP1L 1.3825 | WNT5A 1.3655 | SALL3 1.3649 | GLI2 1.3606 | IFT122 1.3452 | COL2A1 1.3191 | PRRX1 1.2712 | SHH 1.2438 | IMPAD1 1.2243 | HAND2 1.1943 | TFAP2A 1.1936 | GNAS 1.1857 | RARG 1.1840 | SEMA3C 1.1792 | SALL1 1.1703 | RAB23 1.1331 | PRRX2 1.1307 | BMP4 1.1081 | MED1 1.0961 | MSX2 1.0645 | PSEN1 1.0274 | CHD7 1.0210 | PITX1 0.9816 | OSR1 0.9759 | GAS1 0.9741 | FBN2 0.9552 | EN1 0.9522 | SP8 0.9512 | HDAC2 0.9044 | DLX6 0.8896 | IFT88 0.8853 | DLX5 0.8523 | SOX4 0.8314 | HDAC1 0.8048 | KRTAP21-2 0.7966 | BAK1 0.7850 | SFRP2 0.7657 | TFAP2B 0.7079 | FGF10 0.7055 | NOG 0.6617 | KIAA1715 0.6331 | GDF5 0.6266 | CTNNB1 0.5466 | EVI1 | LNP | RALDH2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ovulation cycle (boxplot) | 101 | 103 | 2.759635112769282 | 0.0028932976603675 | 0.04406097569616455 | 0.018575851393188854 | SIRT1 7.4176 | PCYT1B 7.2283 | FAS 3.2882 | ERBB2 3.2295 | SOHLH1 3.0802 | VEGFA 3.0488 | ROBO2 3.0085 | AMH 2.9749 | ADAMTS1 2.9721 | SLIT2 2.8500 | CHAT 2.7603 | MSTN 2.6651 | FGF7 2.5131 | TIMP4 2.4753 | IQCJ-SCHIP1 2.4652 | SLIT3 2.4489 | MSH4 2.4326 | FSHR 2.4105 | SCHIP1 2.3967 | VGF 2.3948 | OXTR 2.3881 | PLA2G4A 2.3298 | AGT 2.2659 | NRIP1 2.1803 | BCL2 2.1766 | CCND2 2.1625 | FOXL2 2.1573 | GDF10 2.1481 | FOXO3 2.0675 | IMMP2L 1.9821 | MMP14 1.9618 | TYRO3 1.9521 | DMC1 1.9224 | BMPR1B 1.9013 | NR5A1 1.8809 | EDN2 1.8797 | ESR1 1.8508 | ESR2 1.8459 | ANXA1 1.8032 | AFP 1.7611 | LHCGR 1.7607 | EIF2B4 1.7419 | CAPN5 1.7012 | STRA8 1.6857 | ICAM1 1.6718 | ANG 1.6605 | PDGFRA 1.6489 | NOS3 1.6288 | INHBA 1.6220 | TGFB2 1.5799 | NPY5R 1.5788 | BMP2 1.5776 | KDR 1.5543 | MMP19 1.5508 | PRL 1.5478 | ADNP 1.5371 | STAT5A 1.5114 | FANCG 1.4995 | SFRP4 1.4173 | CASP2 1.4160 | AXL 1.4159 | LEP 1.4143 | KITLG 1.3781 | CTNNA1 1.3657 | WNT5A 1.3655 | BMP15 1.3595 | CCKBR 1.3511 | NOBOX 1.3482 | SFRP1 1.2842 | UBE3A 1.2776 | TAF4 1.2681 | EIF2B5 1.2665 | PGR 1.2410 | FSHB 1.2331 | FOXC1 1.2136 | PLEKHA1 1.2069 | LFNG 1.1848 | ANGPT1 1.1416 | INHBB 1.1310 | ERMP1 1.1105 | BMP4 1.1081 | ADRBK1 1.0662 | TGFB3 1.0107 | STAT5B 1.0063 | GPR149 0.9780 | INHA 0.8631 | SOD1 0.8543 | SGPL1 0.8268 | BCL2L1 0.8053 | EREG 0.8038 | NKX2-1 0.7775 | FZD4 0.7448 | CAT 0.6876 | SPO11 0.6482 | GNRH1 0.6442 | AHR 0.6079 | CENPI 0.4883 | NHLH2 0.4876 | CCNE1 0.4397 | EIF2B2 0.2862 | KGFLP2 0.1912 | KGFLP1 | estrogen receptor | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
muscle cell homeostasis (boxplot) | 17 | 17 | 2.7590687123663895 | 0.0028983172657433 | 0.04406097569616455 | 0.018518518518518517 | ALDOA 4.0025 | DMD 3.6492 | LARGE 3.1017 | SGCZ 2.5939 | PPP3CB 2.4174 | CAV3 2.3881 | GYLTL1B 2.3164 | GAA 1.9633 | IL6 1.7153 | HIF1A 1.6618 | CAPN3 1.5788 | APC 1.5096 | PLG 1.3287 | CHRNA1 1.3109 | SRF 1.1778 | PFKM 1.1142 | SOD1 0.8543 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
cell-cell junction organization (boxplot) | 119 | 119 | 2.755036686961786 | 0.00293427773484245 | 0.04406097569616455 | 0.018461538461538463 | MPP5 5.2324 | HEG1 4.0972 | CDH2 3.9744 | CDH13 3.9298 | NF2 3.2554 | CLDN23 3.1016 | CDH4 3.0350 | CDH18 2.9750 | NFASC 2.9513 | KIFC3 2.9206 | TLN2 2.8514 | CDH12 2.8169 | MPZ 2.7198 | SNAI2 2.6919 | CLDN9 2.3109 | NLGN4X 2.3043 | PARD6A 2.2550 | LIM2 2.2345 | ARL2 2.2292 | CADM1 2.2215 | AMOT 2.2199 | MPP7 2.2168 | WNT11 2.1927 | CXADR 2.1888 | SHROOM2 2.1572 | SMAD3 2.1433 | ACTB 2.1337 | NUMBL 2.1296 | CDH6 2.1282 | CRB3 2.1267 | PLEKHA7 2.1105 | MARVELD3 2.1095 | RHOC 2.1005 | CLDN1 2.0629 | PARD3 2.0430 | CLDN15 2.0275 | TRPV4 2.0262 | CLDN18 2.0192 | CDH11 1.9918 | ACTG1 1.9056 | JUP 1.9019 | RHOA 1.8947 | STRN 1.8799 | DLG1 1.8617 | TBCD 1.8480 | DSG1 1.8240 | CDH8 1.8008 | PARD6G 1.7998 | GJA4 1.7960 | PTPRO 1.7894 | FBF1 1.7617 | CADM3 1.7482 | CLDN12 1.7433 | PIP5K1C 1.7353 | PVR 1.7307 | CDH24 1.7171 | PVRL2 1.7152 | VCL 1.7125 | HNF4A 1.7052 | GJA5 1.6874 | CDH5 1.6622 | MARVELD2 1.6375 | CDH10 1.6369 | CAMSAP3 1.6054 | CLDN14 1.5897 | TGFB2 1.5799 | OCLN 1.5772 | PARD6B 1.5688 | PVRL1 1.5566 | GJA1 1.5265 | APC 1.5096 | CD9 1.5036 | CCM2 1.4998 | INADL 1.4898 | SMAD7 1.4674 | CLDN20 1.3757 | CLDN22 1.3696 | CTNNA1 1.3657 | CADM2 1.3494 | CDH7 1.3419 | MTDH 1.3350 | GJB2 1.2907 | HDAC7 1.2885 | CNTNAP1 1.2662 | CSF1R 1.2307 | TJP1 1.2276 | FRMPD2 1.2268 | CDH1 1.2150 | GNPAT 1.2058 | SRF 1.1778 | CLDN17 1.1407 | PKN2 1.1257 | ITGB1 1.1192 | CDC42 1.0907 | CLDN19 1.0776 | CTNND1 1.0729 | CDH15 1.0574 | NUMB 1.0524 | MLLT4 1.0402 | DSP 1.0262 | TGFB3 1.0107 | GJB1 0.9815 | CDH9 0.9768 | TLN1 0.9695 | TGFB1 0.9693 | RAMP2 0.9523 | PRKCI 0.9445 | GJC1 0.9440 | CDH3 0.9414 | PVRL4 0.9395 | PVRL3 0.9077 | RAB8B 0.8841 | UGT8 0.8186 | ZNF703 0.7049 | NLGN2 0.6604 | F11R 0.6028 | ECT2 0.5904 | GJD3 0.5757 | CTNNB1 0.5466 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
homophilic cell adhesion (boxplot) | 99 | 142 | 2.747948406929345 | 0.0029984722391243057 | 0.04480286042923962 | 0.018404907975460124 | CDH2 3.9744 | CDH13 3.9298 | PCDH15 3.5572 | PCDH7 3.3527 | CDH4 3.0350 | PTPRT 3.0314 | ROBO2 3.0085 | CDH18 2.9750 | CDH23 2.9737 | PCDHA1 2.9241 | PCDHA10 | PCDHA11 | PCDHA12 | PCDHA13 | PCDHA2 | PCDHA3 | PCDHA4 | PCDHA5 | PCDHA6 | PCDHA7 | PCDHA8 | PCDHA9 | PCDHAC1 | PCDHAC2 | CDH12 2.8169 | PTPRM 2.7283 | FREM2 2.5468 | PTPRF 2.5339 | DSG2 2.5192 | PCDH17 2.4200 | PCDH9 2.4123 | CDH22 2.3943 | CDHR3 2.3675 | DSCAML1 2.3591 | NPTN 2.3588 | CLSTN2 2.3525 | FAT2 2.3507 | PCDHB17 2.2391 | PCDHB5 | PCDHB6 | PCDHB7 2.2391 | CADM1 2.2215 | CDH17 2.1751 | ROBO1 2.1673 | DCHS2 2.1371 | CDH6 2.1282 | PCDH11X 2.1173 | CDH26 2.0238 | DSG3 2.0136 | CDH11 1.9918 | DSC3 1.9514 | RET 1.9319 | PCDH19 1.9028 | FAT3 1.8911 | CDH20 1.8425 | CDHR5 1.8319 | DSG1 1.8240 | CDH8 1.8008 | CADM3 1.7482 | CLSTN1 1.7408 | CELSR1 1.7341 | CDH24 1.7171 | PVRL2 1.7152 | CELSR3 1.6843 | CDH5 1.6622 | CDH10 1.6369 | PCDH1 1.6297 | DSC1 1.6288 | DSC2 1.6288 | PCDHB4 1.5866 | FAT1 1.5616 | PVRL1 1.5566 | CELSR2 1.5268 | DSG4 1.4872 | AMIGO1 1.4658 | PCDHGA1 1.4583 | PCDHGA2 | PCDHGA3 | PCDHGA4 | PCDHGA5 | PCDHGA6 | PCDHGA7 | PCDHGA8 | PCDHGA9 | PCDHGB1 | PCDHGB2 | PCDHGB3 | PCDHGB4 | PCDHGB5 | PCDHGB6 | PCDHGA10 1.3886 | PCDHGA11 | PCDHGB7 | PCDH10 1.3515 | PCDHGA12 1.3503 | CDH7 1.3419 | DCHS1 1.2857 | PCDHGC3 1.2827 | PCDHGC4 | PCDHGC5 | PCDH12 1.2795 | PCDHB14 1.2770 | PCDHB15 1.2770 | PCDHB18 | ESAM 1.2599 | CEACAM1 1.2571 | CDH16 1.2263 | CDH1 1.2150 | CDHR2 1.1935 | PCDHB11 1.1775 | PCDHB12 | PCDHB13 | PCDHB10 1.1729 | PCDHB16 | PCDHB9 | PCDHB8 | CDHR1 1.1424 | ITGB1 1.1192 | PCDH20 1.1066 | CD84 1.0971 | AMIGO2 1.0626 | CDH15 1.0574 | PCDH8 1.0462 | PCDHB2 1.0236 | PCDHB3 0.9967 | CDH9 0.9768 | CDH3 0.9414 | PIK3CB 0.9249 | MPZL2 0.9113 | PVRL3 0.9077 | CLSTN3 0.8999 | PKD1 0.8841 | CDHR4 0.8654 | TRO 0.8440 | FAT4 0.8377 | PCDH18 0.6703 | PCDHB1 0.6509 | CDH19 0.6280 | L1CAM 0.6002 | DKFZp686I11137 | PCDH11Y | PCDHJ | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
T cell activation (boxplot) | 160 | 165 | 2.7441363165928654 | 0.0030335169276944907 | 0.04518830398998561 | 0.01834862385321101 | PRLR 4.7596 | HLA-DMA 4.6143 | TCF3 4.3145 | FYN 3.7055 | TBX21 3.4999 | LCP1 3.4460 | PSEN2 3.3139 | FAS 3.2882 | CARD11 3.1018 | LAT 2.8728 | ITPKB 2.8294 | PRKDC 2.8038 | FLT3 2.7949 | THEMIS 2.7728 | MICB 2.7706 | RAB27A 2.7200 | PIK3CD 2.5941 | PIK3CG 2.5697 | TXK 2.5595 | IRF1 2.4722 | PPP3CB 2.4174 | DPP4 2.3359 | BCL11A 2.3352 | GLI3 2.3270 | CD8B 2.3235 | CCR7 2.3166 | IL15 2.2242 | CCND3 2.2241 | DOCK2 2.2237 | CADM1 2.2215 | MICA 2.1925 | BCL2 2.1766 | JAG2 2.1763 | NCOR1 2.1739 | IKZF1 2.1588 | CD28 2.1569 | CD276 2.1515 | SMAD3 2.1433 | FZD7 2.1227 | CD3D 2.1205 | CD3E 2.1205 | CD3G | SYK 2.1149 | TNFSF14 2.0782 | LIG4 2.0575 | CD4 2.0421 | CDK6 2.0335 | CD8A | WNT1 2.0180 | ELF4 2.0037 | RHOH 1.9833 | INS 1.9742 | CD80 1.9711 | HSH2D 1.9590 | CD86 1.9313 | BCL11B 1.8758 | RELB 1.8635 | DLG1 1.8617 | P2RX7 1.8574 | CD2 1.8423 | BLM 1.8278 | ANXA1 1.8032 | PKNOX1 1.7735 | CBLB 1.7575 | ITGAD 1.7565 | LEF1 1.7470 | SLC11A1 1.7405 | IL6 1.7153 | ZFP36L1 1.7047 | KIF13B 1.6972 | ICAM1 1.6718 | XRCC4 1.6336 | IL4 1.6202 | F2RL1 1.6183 | HSPD1 1.5925 | ATP7A 1.5814 | CD1D 1.5801 | STAT6 1.5795 | PTGER4 1.5596 | NKX2-3 1.5542 | CRTAM 1.5477 | FOXP3 1.5343 | STAT5A 1.5114 | APC 1.5096 | ADAM17 1.5056 | CD1C 1.5041 | CD48 1.4980 | ZFPM1 1.4872 | GIMAP1 1.4862 | GIMAP5 1.4739 | MINK1 1.4611 | RIPK2 1.4586 | PATZ1 1.4531 | NCK2 1.4470 | ADA 1.4333 | PPP3CA 1.4235 | PTPN22 1.4217 | DNAJA3 1.4206 | PTPRC 1.4182 | FUT7 1.4115 | CLEC7A 1.3986 | PRDX2 1.3938 | VAV1 1.3902 | ZAP70 1.3847 | FKBP1A 1.3770 | ITGAL 1.3652 | TNFRSF4 1.3634 | TP53 1.3523 | SATB1 1.3478 | SLA2 1.3387 | MALT1 1.3374 | TNFSF8 1.3265 | LCK 1.3129 | FKBP1B 1.3101 | IFNAR1 1.2926 | ZBTB32 1.2769 | RORC 1.2767 | IL2 1.2715 | SP3 1.2641 | FZD5 1.2625 | CCL19 1.2605 | CCL21 | TREML2 1.2526 | SHH 1.2438 | NHEJ1 1.2416 | SPN 1.2252 | ICOSLG 1.2062 | DDOST 1.1846 | SRF 1.1778 | MYH9 1.1496 | BCL3 1.1329 | RPL22 1.1263 | RAG1 1.1187 | WAS 1.1123 | IL7R 1.1090 | PAX1 1.0990 | NLRC3 1.0876 | ITK 1.0826 | JMJD6 1.0466 | IL7 1.0414 | CD74 1.0390 | IRF4 1.0357 | PSEN1 1.0274 | EOMES 1.0250 | CHD7 1.0210 | STAT5B 1.0063 | WNT4 0.9772 | TGFB1 0.9693 | MPZL2 0.9113 | TNFSF4 0.9088 | IFNG 0.8931 | SOX4 0.8314 | FZD8 0.7752 | LILRB1 0.7574 | IL12B 0.7568 | CD7 0.7475 | NCK1 0.7460 | IL23A 0.7358 | TNFSF18 0.6568 | RAG2 0.6482 | TCF7 0.5551 | CTNNB1 0.5466 | EGR1 0.5440 | BGR | Q4G0T1 | ||||||||||||||||||||||||||||||||||||||||||
mast cell activation involved in immune response (boxplot) | 10 | 10 | 2.737466063791449 | 0.003095725387257442 | 0.045974815325653076 | 0.018292682926829267 | ADORA3 4.1949 | CPLX2 3.2544 | LAT 2.8728 | PIK3CD 2.5941 | PIK3CG 2.5697 | YWHAZ 1.7916 | LYN 1.5986 | LAT2 1.3653 | S100A13 1.3048 | MILR1 0.2667 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
mast cell degranulation (boxplot) | 10 | 10 | 2.737466063791449 | 0.003095725387257442 | 0.045974815325653076 | 0.018292682926829267 | ADORA3 4.1949 | CPLX2 3.2544 | LAT 2.8728 | PIK3CD 2.5941 | PIK3CG 2.5697 | YWHAZ 1.7916 | LYN 1.5986 | LAT2 1.3653 | S100A13 1.3048 | MILR1 0.2667 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
B cell receptor signaling pathway (boxplot) | 27 | 27 | 2.7342967826756976 | 0.0031256835149661155 | 0.04613924366804967 | 0.021212121212121213 | BTK 4.4391 | PRKCB 2.9939 | NFATC2 2.9629 | CD19 2.7102 | TEC 2.6652 | LIME1 2.6410 | PIK3CD 2.5941 | PLCG2 2.4205 | KLHL6 2.2407 | BCL2 2.1766 | SYK 2.1149 | MEF2C 2.0426 | MAPK1 1.9571 | CD38 1.8553 | VAV3 1.8406 | BCAR1 1.6063 | LYN 1.5986 | PTPRC 1.4182 | LAT2 1.3653 | LCK 1.3129 | NCKAP1L 1.2593 | PLEKHA1 1.2069 | MNDA 1.1179 | CTLA4 1.0433 | BLK 1.0417 | CD79A 0.8908 | NFAM1 0.7992 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of histone modification (boxplot) | 51 | 51 | 2.7334811125304457 | 0.0031334358748398294 | 0.04613924366804967 | 0.021148036253776436 | CTCFL 3.9842 | NIPBL 3.6793 | DNMT1 3.5891 | PAXIP1 3.1608 | SNAI2 2.6919 | PPARGC1A 2.4496 | SET 2.3111 | NOS1 2.3035 | CDK9 2.2820 | CTCF 2.2550 | GFI1B 2.2059 | SKI 2.1799 | NCOR1 2.1739 | MAPK8 2.1614 | PAX5 2.1529 | LPIN1 2.1486 | NOC2L 2.1228 | TWIST1 2.0979 | MEN1 2.0976 | SNCA 1.9846 | WDR61 1.9782 | SPI1 1.9461 | CTBP1 1.9311 | IL1B 1.8813 | MAPK3 1.8628 | MYOCD 1.8480 | SREBF1 1.8466 | CTR9 1.8327 | MUC1 1.8194 | MYB 1.7428 | BRCA1 1.7066 | JARID2 1.7060 | RPS6KA4 1.6294 | ARRB1 1.5906 | RPS6KA5 1.5702 | FOXP3 1.5343 | EID1 1.4286 | PML 1.3600 | TP53 1.3523 | BRD7 1.3186 | PYGO2 1.2933 | TAF7 1.2741 | BCOR 1.1468 | DNMT3B 1.0326 | TGFB1 0.9693 | CHEK1 0.8631 | UBE2N 0.7395 | OGT 0.6705 | UBE2B 0.6043 | CCNB1 0.5640 | GATA2 0.4907 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3',5'-cyclic-nucleotide phosphodiesterase activity (boxplot) | 24 | 26 | 2.7318525680081422 | 0.0031489658201462323 | 0.046203744736439914 | 0.02108433734939759 | PDE2A 3.7330 | PDE10A 3.5081 | PDE4B 3.1574 | PDE8A 3.0407 | PDE11A 2.9328 | PDE4D 2.8834 | PDE7B 2.6103 | PDE3A 2.3821 | PDE6C 2.2565 | PDE1C 2.1963 | PDE9A 1.7763 | PDE3B 1.7081 | PDE6A 1.5259 | PDE1A 1.5160 | PDE4C 1.4334 | PDE6H 1.3989 | PDE8B 1.3712 | PDE7A 1.2485 | PDE1B 1.1847 | PDE6B 1.1598 | PDE5A 1.1185 | PDE6G 1.0776 | PDE6D 1.0743 | PDE4A 0.7502 | PDE4B5 | PDE7B variant protein | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
magnesium ion binding (boxplot) | 177 | 179 | 2.7303578928067362 | 0.003163280110788591 | 0.046274810243452265 | 0.021021021021021023 | LHPP 6.4701 | MST4 3.9441 | ATP9A 3.8389 | EYA2 3.7792 | ATP11A 3.7283 | ATP8A2 3.6048 | ADCY10 3.5194 | MARK1 3.3006 | MSH2 3.2026 | MAP3K5 3.1884 | MAP3K7 3.1402 | PRTFDC1 3.1034 | MAP2K7 3.0946 | ATP8B2 3.0740 | SIK3 3.0556 | PRKACB 2.9293 | SIK1 2.8664 | OPA1 2.8384 | MAST4 2.7337 | NT5C3L 2.7017 | FARS2 2.6922 | RPS6KA1 2.6847 | NIM1 2.5585 | COMT 2.5550 | SIK2 2.5468 | RPS6KA2 2.5126 | FOXK2 2.4644 | NT5C1B 2.3958 | NT5C1B-RDH14 | WEE2 2.3902 | PAPOLA 2.3730 | PGM1 2.3707 | CDC42BPA 2.3339 | PKM2 2.3177 | PCK1 2.3007 | GCLC 2.2372 | ATP10D 2.2069 | ATP10A 2.1905 | NUDT7 2.1687 | CDC42BPG 2.0976 | NUAK2 2.0868 | THG1L 2.0862 | MAP3K12 2.0825 | ENO1 2.0766 | ZAK 2.0492 | MTPAP 2.0090 | SNCA 1.9846 | IRAK3 1.9617 | ATP8B4 1.9597 | IRAK4 1.9582 | SRPK1 1.9424 | MAST1 1.9421 | ENO4 1.9353 | PGM2 1.9257 | NT5C1A 1.9097 | STK38 1.9090 | SRPK2 1.8699 | ITPK1 1.8685 | P2RX7 1.8574 | BRSK2 1.8300 | TGM3 1.8046 | FARSB 1.7908 | IDI1 1.7868 | ERN2 1.7848 | OXSR1 1.7773 | MAST3 1.7643 | RRAGC 1.7641 | ATP9B 1.7613 | ABL2 1.7537 | HACL1 1.7486 | BRSK1 1.7013 | PGM5 1.7013 | STK3 1.6982 | MOV10L1 1.6922 | CERK 1.6844 | REV1 1.6804 | NLRC4 1.6790 | STK4 1.6533 | WEE1 1.6421 | TSSK2 1.6414 | RPS6KA4 1.6294 | CDC42BPB 1.6242 | MARK2 1.6028 | PI4K2A 1.5996 | NUDT5 1.5956 | ATP10B 1.5905 | RPS6KA5 1.5702 | TESC 1.5618 | NME1 1.5583 | ATP4A 1.5510 | STK38L 1.5355 | PRPSAP1 1.5010 | SPHK1 1.5010 | MAP3K6 1.5004 | ADPRHL1 1.4793 | MAP3K13 1.4769 | SNRK 1.4622 | TSSK1B 1.4538 | ABL1 1.4403 | NLK 1.4362 | DCK 1.4347 | IDH2 1.4181 | TSSK6 1.4126 | PDXK 1.4121 | PPM1B 1.4090 | MAP3K8 1.4023 | PTEN 1.3846 | ATP8B1 1.3825 | PSPH 1.3768 | RPS6KA3 1.3752 | ERN1 1.3742 | ADSSL1 1.3671 | PPM1N 1.3560 | GTPBP10 1.3494 | CSNK1G2 1.3418 | PRPS2 1.3147 | MAST2 1.3088 | PPM1A 1.3037 | GEM 1.3008 | HPGDS 1.2966 | PIF1 1.2919 | ATP11B 1.2915 | GSS 1.2798 | WRN 1.2667 | ADPRH 1.2637 | ATP8A1 1.2627 | RNASEH1 1.2618 | PGM3 1.2616 | IDH3A 1.2472 | PPA1 1.2359 | AASDHPPT 1.2291 | ILVBL 1.1983 | IDH3G 1.1942 | IDH3B 1.1853 | PINK1 1.1846 | NT5C3 1.1841 | NUDT3 1.1734 | STK11 1.1724 | DYRK3 1.1675 | MTHFD2 1.1372 | STK36 1.1173 | MSH6 1.1138 | RPS6KA6 1.1135 | TKT 1.1087 | PRPS1L1 1.1035 | ENDOV 1.0791 | PPA2 1.0500 | TDP2 1.0389 | TSSK4 1.0126 | ENO3 1.0107 | IDH1 1.0100 | GTPBP5 1.0005 | S100P 0.9961 | FIGNL1 0.9847 | ATP8B3 0.9821 | NEK6 0.9782 | HMGCL 0.9201 | ENO2 0.9115 | SRR 0.9038 | BPNT1 0.9032 | LATS1 0.8990 | FOXK1 0.8877 | PKLR 0.8529 | MAPK12 0.8399 | ENOPH1 0.8222 | HPRT1 0.8115 | ADSS 0.7750 | ICK 0.7731 | PRPS1 0.6901 | DYRK2 0.6555 | FAN1 0.6494 | LAP3 0.6447 | TSSK3 0.6166 | FDXACB1 0.5440 | ATP11C 0.5439 | PRPSAP2 0.5359 | DCTPP1 0.3424 | FEN1 0.1999 | MLTK | ||||||||||||||||||||||||||||
myosin complex (boxplot) | 64 | 65 | 2.728061609492061 | 0.0031853854040826413 | 0.04645908383387398 | 0.020958083832335328 | MYO1C 4.9972 | MYO16 3.5430 | MYO1D 3.2744 | MYO3B 2.8660 | MYO18A 2.8163 | MYOM2 2.7945 | CGNL1 2.7612 | MYOM1 2.5153 | MYO1E 2.5057 | MYO9B 2.3989 | MYO1H 2.3855 | MYO15B 2.3596 | MYH11 2.2753 | MYO18B 2.2179 | MYO9A 2.1801 | TRIM32 2.1399 | MYO3A 2.1330 | MYBPC1 2.0903 | MYL7 2.0341 | MYO5B 2.0328 | MYO1B 2.0278 | MYL6 1.9522 | MYL6B 1.9522 | MYBPC3 1.9461 | MYO6 1.9297 | MYL3 1.8709 | MYH6 1.8142 | MYH7 1.8142 | MYO10 1.7867 | MYO19 1.7194 | MYBPH 1.7070 | MYL9 1.7057 | MYO7A 1.7012 | MYH15 1.7006 | MYO5C 1.6330 | MYO1A 1.6056 | MYL12A 1.5886 | MYL12B | MYO5A 1.5529 | MYL2 1.5502 | MYO1G 1.5496 | MYH1 1.5065 | MYH2 1.5065 | MYH10 1.4980 | MYO1F 1.4447 | MYH14 1.4431 | MYBPC2 1.4389 | FILIP1L 1.3801 | MYO7B 1.3778 | MYL1 1.3574 | MYH7B 1.2798 | MYL4 1.2440 | MYH13 1.1562 | MYH4 1.1555 | MYH8 1.1555 | DYNLL2 1.1549 | MYH9 1.1496 | BMF 1.1100 | MYH3 1.0276 | SHROOM1 0.9655 | SHROOM4 0.9493 | CGN 0.8677 | MYO15A 0.7632 | MYL5 0.6911 | MYLPF 0.4455 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
skeletal muscle fiber development (boxplot) | 37 | 37 | 2.726990371549745 | 0.0031957452045254797 | 0.04647146151580801 | 0.020895522388059702 | GPHN 5.9364 | ERBB2 3.2295 | CAV2 2.8160 | CHAT 2.7603 | MUSK 2.5943 | COL4A1 2.5872 | CACNB2 2.2123 | HOMER1 2.1943 | SKI 2.1799 | DNER 2.1720 | LRP4 2.1606 | APP 2.1303 | PDZRN3 2.0541 | WNT10B 2.0180 | TNC 1.9083 | GPX1 1.8947 | AFG3L2 1.8657 | RCAN1 1.8416 | MYOG 1.5902 | LRRK2 1.5730 | RYR1 1.5561 | KIAA1161 1.5218 | LAMB2 1.4979 | F2R 1.4291 | PPP3CA 1.4235 | DNAJA3 1.4206 | CACNA1S 1.3954 | CACNG2 1.3692 | ALS2 1.3539 | CHRNA1 1.3109 | COL4A5 1.3070 | MYOD1 1.2690 | DVL1 1.2676 | DOK7 1.2147 | NRD1 1.0284 | ACTA1 0.9736 | SNTA1 0.5644 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of fatty acid metabolic process (boxplot) | 27 | 27 | 2.7261494289081107 | 0.0032038990805578482 | 0.04647146151580801 | 0.020833333333333332 | FABP1 3.5813 | MLXIPL 3.3990 | C1QTNF2 3.0733 | APOA4 2.5911 | APOA5 2.5911 | PPARGC1A 2.4496 | PLA2G4A 2.3298 | AGT 2.2659 | TWIST1 2.0979 | PTGS2 1.9806 | AVP 1.9195 | IRS1 1.9115 | MID1IP1 1.8925 | IRS2 1.8084 | ANXA1 1.8032 | AKT2 1.7769 | GHSR 1.7166 | HNF4A 1.7052 | PPARG 1.6692 | ABCD2 1.6687 | APOC2 1.3441 | ADIPOQ 1.3289 | NR1H3 1.3265 | CPT1A 1.1834 | NR1H2 1.1632 | PPARA 1.0266 | AVPR1A 0.6808 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
myelin sheath (boxplot) | 31 | 31 | 2.72347654049206 | 0.0032299401646664894 | 0.04669079184781203 | 0.020771513353115726 | MPP5 5.2324 | TSPAN2 3.2886 | ERBB2 3.2295 | MBP 3.0687 | PMP22 2.6336 | RTN4 2.3237 | CNTN2 2.2820 | GJC2 2.2368 | TUBB4A 2.2033 | SRD5A1 2.1992 | BCL2 2.1766 | MPDZ 2.0535 | PRX 2.0418 | EXOC4 1.9205 | MAG 1.8819 | DLG1 1.8617 | PRKCZ 1.7929 | PLLP 1.7913 | ITPR3 1.7657 | LLGL1 1.5422 | PLP1 1.4162 | ANXA2 1.4037 | PTEN 1.3846 | CDH1 1.2150 | ATP1A3 1.1872 | ITGB1 1.1192 | ERMN 1.0218 | PRKCI 0.9445 | GJC3 0.7123 | STX4 0.6681 | ANXA2P2 0.6424 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity (boxplot) | 17 | 17 | 2.720756466127147 | 0.0032566363000581244 | 0.04693783174656046 | 0.020710059171597635 | NRXN1 3.6097 | SHANK1 3.1256 | NLGN1 2.7866 | CACNG3 2.6709 | CACNG4 2.2546 | RELN 2.2249 | CNIH2 2.1101 | SHANK3 2.0446 | CACNG7 1.9540 | CNIH3 1.8983 | MAPK8IP2 1.8627 | CACNG5 1.6745 | NLGN3 1.5936 | MINK1 1.4611 | CACNG2 1.3692 | CACNG8 1.2699 | NLGN2 0.6604 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
heart morphogenesis (boxplot) | 158 | 160 | 2.7134690499547207 | 0.0033291393803588365 | 0.04784169121303904 | 0.02064896755162242 | HEG1 4.0972 | BBS5 3.9745 | HES1 3.7965 | NIPBL 3.6793 | TCAP 3.2295 | RYR2 3.1737 | INSR 3.1624 | VEGFA 3.0488 | ADAMTS1 2.9721 | ANKRD1 2.9349 | PROX1 2.8868 | OVOL2 2.7834 | SMARCA4 2.7826 | FGFR2 2.7650 | T 2.7408 | SNAI2 2.6919 | FHL2 2.6776 | TBX3 2.6289 | SOX18 2.5964 | SOX9 2.4914 | TTN 2.4386 | FZD1 2.4363 | BMPR1A 2.4359 | RTN4 2.3237 | MKL2 2.3092 | DLC1 2.2963 | NCOR2 2.2598 | RBP4 2.2565 | ZFPM2 2.2503 | NKX2-5 2.2385 | COL4A3BP 2.2085 | ENG 2.2047 | WNT11 2.1927 | SMAD3 2.1433 | PTCH1 2.1082 | TWIST1 2.0979 | ALDH1A2 2.0957 | LRP6 2.0780 | STIL 2.0744 | EYA1 2.0489 | MEF2C 2.0426 | SAV1 2.0321 | VANGL2 2.0307 | TNNI3 2.0145 | TBX5 1.9756 | TH 1.9742 | GAA 1.9633 | GATA4 1.9478 | MYBPC3 1.9461 | HTR2B 1.9303 | COL5A1 1.9082 | PPP1R13L 1.9069 | JUN 1.8868 | MYL3 1.8709 | TBX1 1.8661 | TEK 1.8630 | SUFU 1.8618 | HEY1 1.8533 | SETDB2 1.8523 | FOXF1 1.8463 | TNNC1 1.8440 | MYH6 1.8142 | MYH7 1.8142 | SMO 1.8103 | FZD2 1.8049 | FGF8 1.7956 | RXRA 1.7596 | ADAM15 1.7569 | TNNI1 1.7410 | ATF2 1.7025 | TGFBR3 1.7014 | NOTCH1 1.6712 | RBM15 1.6666 | HIF1A 1.6618 | CYR61 1.6494 | FGFRL1 1.6492 | NODAL 1.6471 | LBX1 1.6412 | WNT3A 1.6407 | MIB1 1.6201 | SOX11 1.6081 | TPM1 1.5971 | TGFB2 1.5799 | NPY1R 1.5788 | NPY5R 1.5788 | BMP2 1.5776 | WNT2 1.5764 | GATA3 1.5648 | BBS4 1.5605 | RYR1 1.5561 | MYL2 1.5502 | GATA6 1.5382 | GJA1 1.5265 | IFT52 1.5182 | MKKS 1.5151 | MSX1 1.4876 | ZFPM1 1.4872 | SMAD7 1.4674 | COL11A1 1.4339 | ZIC3 1.4228 | EPHB4 1.4218 | FOXC2 1.4158 | CPE 1.4083 | PTK2 1.3822 | FKBP1A 1.3770 | WNT5A 1.3655 | LY6E 1.3482 | TBX2 1.3390 | TBX20 1.3377 | COL2A1 1.3191 | DVL2 1.2681 | EFNA1 1.2501 | SHH 1.2438 | SMARCD3 1.2326 | HEYL 1.2247 | TNNT2 1.2243 | FOXJ1 1.2168 | FOXC1 1.2136 | GSK3A 1.2130 | HAND2 1.1943 | TFAP2A 1.1936 | SEMA3C 1.1792 | SRF 1.1778 | FOXS1 1.1734 | BMP10 1.1425 | TAB1 1.1406 | IHH 1.1219 | BMP4 1.1081 | ACTC1 1.1031 | MYLK2 1.0997 | MED1 1.0961 | UBE4B 1.0761 | PITX2 1.0752 | BAZ1B 1.0715 | MSX2 1.0645 | ACVR1 1.0582 | POU4F1 1.0505 | PSEN1 1.0274 | CHD7 1.0210 | MESP1 1.0064 | AHI1 0.9870 | EGLN1 0.9579 | BBS7 0.9228 | PTCD2 0.9115 | IFT88 0.8853 | HEY2 0.8433 | SOX17 0.8386 | SOX4 0.8314 | NPY2R 0.8105 | DVL3 0.7715 | SFRP2 0.7657 | ISL1 0.7237 | WHSC1 0.6859 | FOXH1 0.6677 | WNT16 0.6218 | HAND1 0.5859 | CITED2 0.4310 | LEFTY1 0.4136 | HNTN1 | RALDH2 | |||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of peptidase activity (boxplot) | 113 | 113 | 2.7133934920330427 | 0.003329898653553376 | 0.04784169121303904 | 0.020588235294117647 | SIRT1 7.4176 | EGLN3 4.8828 | CAV1 3.7656 | DAP 3.6330 | HIP1 3.4696 | FAS 3.2882 | MAP3K5 3.1884 | TNF 3.0639 | CDKN2A 3.0353 | BAX 3.0299 | BCL2L10 2.8173 | BBC3 2.6870 | NGFRAP1 2.6339 | PCOLCE 2.6139 | C6 2.3864 | ADRM1 2.3426 | CASP3 2.3272 | TNFRSF10B 2.3119 | DLC1 2.2963 | COL4A3 2.2501 | AIFM3 2.2178 | CASP1 2.2143 | ROBO1 2.1673 | FOXL2 2.1573 | SMAD3 2.1433 | RHOC 2.1005 | MEN1 2.0976 | BCL2L13 2.0773 | RIPK1 2.0686 | FIS1 2.0275 | SNCA 1.9846 | MYC 1.9575 | P2RX1 1.9501 | TNFSF15 1.8847 | TRADD 1.8740 | BOK 1.8520 | CARD8 1.8181 | FASLG 1.8023 | IFI27 1.7714 | CLPX 1.7702 | PMAIP1 1.7492 | APAF1 1.7480 | DIABLO 1.6957 | BAD 1.6791 | NLRC4 1.6790 | PPARG 1.6692 | CYR61 1.6494 | NODAL 1.6471 | WNT3A 1.6407 | REST 1.6316 | NKX3-1 1.6263 | SIVA1 1.6238 | ACVR1C 1.6115 | PSMD14 1.6027 | HSPD1 1.5925 | HSPE1 1.5925 | PCOLCE2 1.5906 | NLRP1 1.5846 | NLRP3 1.5820 | PDCD6 1.5772 | CASP9 1.5727 | NLRP2 1.5666 | MUL1 1.5551 | RPS27L 1.5118 | VCP 1.4995 | C9 1.4511 | NLRP12 1.4448 | F2R 1.4291 | DNAJA3 1.4206 | FOXQ1 1.4147 | TNFSF10 1.4107 | JAK2 1.4043 | MTCH1 1.3995 | FADD 1.3890 | HMGB1 1.3874 | ALOX12 1.3844 | PML 1.3600 | LCK 1.3129 | CASP12 1.3056 | SLC11A2 1.3019 | TPD52L1 1.2547 | UACA 1.2445 | CASP7 1.2327 | BCL2L11 1.2301 | F3 1.2282 | TERF1 1.2249 | CYCS 1.1994 | PPM1F 1.1863 | RPS3 1.1846 | CR1 1.1828 | CASP8 1.1822 | CDKN1B 1.1519 | APOPT1 1.0707 | TRAF2 1.0448 | NOD1 1.0056 | CTSH 0.9922 | IFNB1 0.9877 | SOX7 0.9686 | CTGF 0.9616 | CCK 0.9390 | TNFRSF10A 0.9347 | MOAP1 0.9186 | SENP1 0.8464 | FAM162A 0.8016 | AIFM1 0.7907 | BAK1 0.7850 | EIF2AK3 0.7800 | IFT57 0.7567 | BCAP31 0.7171 | HTRA2 0.7064 | PSME3 0.7018 | CASP8AP2 0.6842 | PYCARD 0.4005 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
smooth muscle contraction (boxplot) | 40 | 41 | 2.712591129912969 | 0.003337971111587068 | 0.04784169121303904 | 0.020527859237536656 | SULF2 3.5216 | KCNMA1 3.3055 | MYLK 3.2871 | ACTA2 3.1316 | SULF1 2.9550 | PDE4D 2.8834 | CNN3 2.5363 | TPCN2 2.5016 | BDKRB2 2.4033 | EDN1 2.3459 | MYH11 2.2753 | AGT 2.2659 | TRPV1 2.1980 | ADRA1A 2.1619 | ROCK2 2.0790 | MYL7 2.0341 | CHRM3 1.9459 | HTR2B 1.9303 | EDN2 1.8797 | DLG1 1.8617 | EDNRB 1.7889 | KNG1 1.7229 | TSHZ3 1.5963 | DRD2 1.5853 | DRD1 1.4777 | SMTN 1.4140 | P2RX3 1.3783 | TACR1 1.3533 | FKBP1B 1.3101 | HTR1D 1.2345 | GAL 1.2052 | CHRNB4 1.1921 | GDNF 1.1771 | ROCK1 1.1687 | EDN3 1.1118 | SSTR2 1.1051 | CHRNB2 0.9425 | PIK3C2A 0.8669 | EDNRA 0.8058 | NMUR1 0.7701 | RP5-1049G16.1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
negative regulation of cytokine-mediated signaling pathway (boxplot) | 24 | 24 | 2.7058835330578717 | 0.003406146656044662 | 0.0485202115493709 | 0.02046783625730994 | CAV1 3.7656 | SLIT2 2.8500 | IL1RN 2.8456 | PXDN 2.8160 | PTPRF 2.5339 | NLRC5 2.5068 | SLIT3 2.4489 | IL36RN 2.2828 | ROBO1 2.1673 | GAS6 1.9676 | IRAK3 1.9617 | CCL5 1.8122 | GSTP1 1.7474 | PALM3 1.6861 | IL6ST 1.6793 | PPARG 1.6692 | F2RL1 1.6183 | DNAJA3 1.4206 | PTPRC 1.4182 | ADIPOQ 1.3289 | NR1H3 1.3265 | NR1H2 1.1632 | ZNF675 1.1570 | SIGIRR 0.7797 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of endocytosis (boxplot) | 117 | 120 | 2.7045804337141397 | 0.0034195355116330983 | 0.04856933287743988 | 0.02040816326530612 | BICD1 4.2108 | CDH13 3.9298 | PICALM 3.8576 | CAV1 3.7656 | HIP1 3.4696 | MAGI2 3.4637 | AMPH 3.4482 | VEGFA 3.0488 | APOC3 3.0248 | GNB2L1 3.0025 | EHD4 2.9874 | RSPO1 2.8111 | NLGN1 2.7866 | SCARB1 2.6205 | PTX3 2.6077 | APOA5 2.5911 | SNAP91 2.4483 | CAMK1D 2.4333 | LRSAM1 2.3345 | BIN1 2.3168 | NEDD4L 2.3099 | SERPINE1 2.3072 | TUB 2.3045 | PLD2 2.2800 | CALR 2.1592 | SYK 2.1149 | C3 2.0782 | PACSIN3 2.0740 | SH3GL2 2.0435 | SCYL2 2.0365 | MFGE8 2.0138 | ATAD1 2.0096 | SNCA 1.9846 | PRKD1 1.9823 | CBL 1.9784 | SFTPD 1.9782 | GAS6 1.9676 | TULP1 1.9365 | STON2 1.9324 | RAC1 1.9125 | AZU1 1.9033 | PRTN3 | GPC3 1.8708 | GH1 1.8449 | VTN 1.8442 | AHSG 1.8397 | MERTK 1.8314 | PPT1 1.7921 | ABR 1.7595 | ABL2 1.7537 | ITGAV 1.7509 | STON1 1.7470 | SNX17 1.7419 | SLC11A1 1.7405 | SYNJ2BP 1.7375 | SGIP1 1.7021 | GREM1 1.6695 | WNT3A 1.6407 | PACSIN1 1.6218 | MIB1 1.6201 | F2RL1 1.6183 | DRD2 1.5853 | KIAA0226 1.5617 | TNK2 1.5282 | CALY 1.4903 | PCSK9 1.4808 | HCK 1.4790 | CD36 1.4667 | ACTN4 1.4437 | ABL1 1.4403 | LDLRAP1 1.4279 | PTPN1 1.4205 | SFRP4 1.4173 | CLEC7A 1.3986 | BCR 1.3878 | AP2S1 1.3442 | APOC1 1.3441 | APOC2 | ADIPOQ 1.3289 | NR1H3 1.3265 | CNN2 1.2907 | EPN2 1.2666 | CCL19 1.2605 | CCL21 | NCKAP1L 1.2593 | FGR 1.1781 | SELE 1.1773 | NR1H2 1.1632 | DKK1 1.1626 | RAB5B 1.1593 | ARF6 1.1563 | CBLL1 1.1540 | WASL 1.1528 | ATXN2 1.1522 | ANGPT1 1.1416 | SCAMP5 1.1254 | CD63 1.1226 | ITGB1 1.1192 | MBL2 1.1098 | SPACA3 1.1041 | HNRNPK 1.0984 | RAB5C 1.0789 | TSC2 1.0731 | MTMR2 1.0519 | PACSIN2 1.0362 | AAK1 0.9958 | CLIP3 0.9895 | AHI1 0.9870 | TGFB1 0.9693 | RAB4A 0.9659 | PIK3CB 0.9249 | FCER1G 0.8951 | CD47 0.8677 | OPHN1 0.8605 | ZFYVE16 0.7664 | LILRB1 0.7574 | NOD2 0.6871 | CCL2 0.6763 | SYNJ1 0.6101 | GATA2 0.4907 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of cell development (boxplot) | 149 | 149 | 2.702639998619873 | 0.003439560398803776 | 0.04871215103929058 | 0.020348837209302327 | NTRK3 4.8124 | HES1 3.7965 | PTPRD 3.6941 | SCARF1 3.2573 | VEGFA 3.0488 | CDH4 3.0350 | ROBO2 3.0085 | HOXA11 2.9921 | ASPA 2.8861 | SOX8 2.8542 | SLIT2 2.8500 | TIAM1 2.8400 | OPRM1 2.8228 | NTRK2 2.7766 | PLXNB2 2.7490 | DLL3 2.7304 | EPHB2 2.7088 | XRCC6 2.5915 | DSCAM 2.5746 | CXCL12 2.5696 | PTPRF 2.5339 | SERPINF1 2.4022 | PDE3A 2.3821 | NPTN 2.3588 | BCL11A 2.3352 | GLI3 2.3270 | RTN4 2.3237 | TNFRSF12A 2.3109 | FOXG1 2.2887 | NGFR 2.2572 | MAP1B 2.2447 | OTP 2.2004 | STK25 2.1927 | PRKCH 2.1900 | BCL2 2.1766 | ROBO1 2.1673 | FXN 2.1599 | TP73 2.1456 | SMAD3 2.1433 | TRIM32 2.1399 | NUMBL 2.1296 | BCL9L 2.1102 | TWIST1 2.0979 | TCF7L2 2.0892 | WNT3 2.0876 | LIG4 2.0575 | TWF2 2.0553 | SHANK3 2.0446 | NGF 2.0438 | DCT 2.0319 | ISLR2 2.0308 | IL1RAPL1 2.0206 | DISC1 2.0102 | ACTR3 2.0099 | RFX3 2.0015 | RGS14 1.9785 | GRM5 1.9765 | RHOA 1.8947 | PAX2 1.8357 | HOXD11 1.8126 | SMO 1.8103 | NKX6-2 1.8055 | XRCC5 1.7960 | ANAPC2 1.7859 | LEF1 1.7470 | WWTR1 1.7412 | ID2 1.6791 | BAD 1.6791 | PAX6 1.6766 | NOTCH1 1.6712 | PPARG 1.6692 | HIF1A 1.6618 | RELA 1.6587 | WNT3A 1.6407 | XRCC4 1.6336 | SERPINE2 1.6272 | SOX11 1.6081 | SMAD4 1.6061 | LYN 1.5986 | DRD2 1.5853 | TGFB2 1.5799 | BMP2 1.5776 | NDEL1 1.5703 | VEGFC 1.5569 | MEG3 1.5421 | ADNP 1.5371 | CAPRIN1 1.5227 | XRCC2 1.5169 | EP300 1.4888 | COL1A1 1.4835 | LIF 1.4805 | DICER1 1.4798 | AMIGO1 1.4658 | ASCL1 1.4512 | PLAG1 1.4461 | SNAI1 1.3990 | SEMA4D 1.3860 | SMAD1 1.3854 | AXIN2 1.3665 | ADIPOQ 1.3289 | CXCR4 1.2607 | SHH 1.2438 | SMARCD3 1.2326 | NTN1 1.2089 | GFAP 1.2059 | SOX10 1.2019 | LIMK1 1.1825 | ZNF488 1.1776 | GDNF 1.1771 | NKX6-1 1.1771 | STK11 1.1724 | TSPO 1.1685 | BAMBI 1.1573 | MET 1.1441 | TRPV2 1.1404 | PRPF19 1.1381 | ILK 1.1347 | PDE5A 1.1185 | BMP4 1.1081 | CLCF1 1.0800 | CAPRIN2 1.0754 | NUMB 1.0524 | CDKL5 1.0190 | TGFB3 1.0107 | SMAD2 1.0065 | NTF3 0.9832 | NKX2-2 0.9814 | TGFB1 0.9693 | PRKCI 0.9445 | HDAC2 0.9044 | EPB41L5 0.8760 | CNTF 0.8746 | SPEN 0.8488 | PAFAH1B1 0.8148 | OLIG2 0.8085 | TGFB1I1 0.7938 | ACE 0.7753 | SKIL 0.7578 | SEMA7A 0.7223 | ZNF703 0.7049 | DIXDC1 0.6947 | PLXNB1 0.6552 | PAX8 0.6248 | ARHGDIA 0.6161 | SYNJ1 0.6101 | SOX2 0.5800 | CTNNB1 0.5466 | SNW1 0.5348 | MAPT 0.4387 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
T-tubule (boxplot) | 23 | 24 | 2.7012637040177188 | 0.003453827270094467 | 0.04877283249040915 | 0.020289855072463767 | KCNJ12 5.2371 | SCN2A 3.6519 | KCNJ5 3.0325 | SLC8A1 2.7718 | CAMK2D 2.5615 | VDR 2.3912 | CAV3 2.3881 | SCN5A 2.2668 | SLC30A1 2.0329 | CACNA2D1 1.9982 | ESR1 1.8508 | CASQ1 1.6978 | KCNJ3 1.6361 | CAPN3 1.5788 | RYR1 1.5561 | CACNA1S 1.3954 | PRKAR2A 1.3064 | AKAP7 1.2143 | CACNB1 1.1775 | KCNJ11 1.1557 | TGFB3 1.0107 | EDNRA 0.8058 | KCNJ18 0.4591 | estrogen receptor | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
synaptic vesicle membrane (boxplot) | 50 | 50 | 2.700481169429344 | 0.003461962823706699 | 0.04877283249040915 | 0.02023121387283237 | VAMP1 4.1635 | SYT9 3.5016 | ICA1 3.4698 | AMPH 3.4482 | ATP6V1G2-DDX39B 3.0639 | STX1A 2.7012 | SYT1 2.6792 | DMXL2 2.5794 | SLC6A17 2.4874 | SV2C 2.4442 | TMEM163 2.3689 | SYNPR 2.3480 | SYT12 2.2060 | SV2A 2.1873 | C16orf70 2.1433 | SLC18A2 2.0880 | SYN3 2.0801 | SLC17A8 2.0171 | DTNBP1 2.0039 | SLC17A6 1.8970 | SYT4 1.8726 | SLC17A7 1.7655 | ABCC8 1.7488 | RPH3A 1.6628 | OTOF 1.6397 | SLC32A1 1.6305 | SV2B 1.6279 | DRD2 1.5853 | SEMA4C 1.5761 | DOC2A 1.5395 | SYN1 1.4729 | SYNGR1 1.4155 | SYT11 1.4142 | SNAPIN 1.3340 | SYT2 1.2635 | SYT7 1.2604 | SYT5 1.2326 | SYT3 1.2324 | GABRA2 1.2072 | ZNRF1 1.2006 | SVOP 1.1970 | SCAMP5 1.1254 | VAMP2 1.0699 | SYT10 1.0421 | SYT6 1.0354 | CACFD1 1.0115 | SLC30A3 0.9730 | GRIA2 0.9514 | GAD2 0.8924 | SYP 0.8425 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of purine nucleotide biosynthetic process (boxplot) | 63 | 64 | 2.699579707421417 | 0.003471356130516412 | 0.04877283249040915 | 0.020172910662824207 | ABCA1 5.6064 | ADORA3 4.1949 | GHRH 3.4507 | GNAL 3.0690 | PID1 2.9916 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | GUCY1A3 2.4867 | MC1R 2.3626 | ADORA2B 2.3294 | GLP1R 2.2306 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | ADCYAP1 1.8068 | CAP1 1.7921 | LHCGR 1.7607 | ADM 1.7485 | MTNR1A 1.7179 | RAF1 1.7090 | GHRHR 1.6541 | ADRB1 1.6047 | P2RY11 1.5469 | ADNP 1.5371 | NPPC 1.5320 | INSL3 1.5247 | DRD1 1.4777 | RAMP1 1.4694 | APOE 1.4398 | ADCY7 1.4224 | MRAP 1.4047 | CRHR1 1.3545 | MC5R 1.3486 | NPR1 1.3340 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | CALCR 1.1467 | MC4R 1.1026 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | HCTR-6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of nucleotide biosynthetic process (boxplot) | 63 | 64 | 2.699579707421417 | 0.003471356130516412 | 0.04877283249040915 | 0.020172910662824207 | ABCA1 5.6064 | ADORA3 4.1949 | GHRH 3.4507 | GNAL 3.0690 | PID1 2.9916 | NTRK2 2.7766 | CAP2 2.7244 | PTHLH 2.5819 | MC2R 2.5653 | RXFP2 2.5511 | AKAP12 2.5248 | ADCYAP1R1 2.5080 | GUCY1A3 2.4867 | MC1R 2.3626 | ADORA2B 2.3294 | GLP1R 2.2306 | PRKCA 2.1719 | VIPR2 2.1292 | NTRK1 2.0462 | AVP 1.9195 | ACR 1.8804 | CALCRL 1.8557 | VIP 1.8350 | ADCYAP1 1.8068 | CAP1 1.7921 | LHCGR 1.7607 | ADM 1.7485 | MTNR1A 1.7179 | RAF1 1.7090 | GHRHR 1.6541 | ADRB1 1.6047 | P2RY11 1.5469 | ADNP 1.5371 | NPPC 1.5320 | INSL3 1.5247 | DRD1 1.4777 | RAMP1 1.4694 | APOE 1.4398 | ADCY7 1.4224 | MRAP 1.4047 | CRHR1 1.3545 | MC5R 1.3486 | NPR1 1.3340 | ADRB3 1.3060 | ADORA2A 1.3027 | DRD5 1.2989 | NF1 1.2913 | PTH 1.2270 | MRAP2 1.2190 | GSK3A 1.2130 | GCG 1.2112 | GNAS 1.1857 | CALCR 1.1467 | MC4R 1.1026 | ADRB2 1.0467 | GIPR 1.0312 | MC3R 0.9684 | AKAP5 0.9641 | RAMP2 0.9523 | GPR65 0.8893 | CALCA 0.8098 | EDNRA 0.8058 | AVPR2 0.7029 | HCTR-6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
microvillus (boxplot) | 62 | 63 | 2.698016615828863 | 0.0034876979474230962 | 0.04877283249040915 | 0.02005730659025788 | MYO1C 4.9972 | AQP5 4.0312 | IQGAP2 3.8713 | CD302 3.7173 | PCDH15 3.5572 | MPP1 3.2590 | ERBB2 3.2295 | CDH23 2.9737 | PODXL 2.9223 | WWOX 2.7908 | SCARB1 2.6205 | PROM2 2.4352 | DOCK4 2.3990 | OXTR 2.3881 | ATP6V1B1 2.1332 | USH2A 2.0822 | TWF2 2.0553 | GIF 2.0530 | LOXHD1 2.0404 | PDPN 1.9883 | SLC27A4 1.9556 | PROM1 1.9541 | FSCN2 1.9056 | GRXCR1 1.8854 | TEK 1.8630 | TPRN 1.7859 | CLIC4 1.7778 | VIL1 1.7405 | VCAM1 1.7110 | MYO7A 1.7012 | ATP6V1E1 1.6865 | CLIC5 1.6546 | MYO1A 1.6056 | ENPP7 1.5411 | PDGFA 1.5347 | KPTN 1.4933 | SLC4A7 1.4843 | MUC20 1.4838 | ATP6V1B2 1.4506 | ESPN 1.4330 | USH1C 1.4192 | CFTR 1.3770 | DPEP1 1.3546 | TBC1D10A 1.3510 | MTTP 1.2284 | CA9 1.1946 | ANGPT1 1.1416 | EZR 1.1330 | RDX 1.1316 | CTSL2 1.1085 | ATP6V1A 1.0601 | TGFB1 0.9693 | DCXR 0.8880 | KCNJ10 0.8338 | MYO15A 0.7632 | ADCY6 0.7536 | MSN 0.7412 | SLC9A3R1 0.7026 | CTNNB1 0.5466 | FABP2 0.4716 | CA2 0.3746 | HYAL2 0.2244 | WHRN | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
signal transduction by p53 class mediator resulting in induction of apoptosis (boxplot) | 27 | 27 | 2.69640342629868 | 0.003504635950010271 | 0.04878533120156748 | 0.02 | SIRT1 7.4176 | MSH2 3.2026 | HIPK2 3.1565 | TP63 3.0850 | SIK1 2.8664 | BBC3 2.6870 | USP28 2.2572 | BAG6 2.1586 | TP73 2.1456 | BOK 1.8520 | PPP2R5C 1.8424 | PMAIP1 1.7492 | RPS27L 1.5118 | MYBBP1A 1.4984 | EP300 1.4888 | AEN 1.4179 | PML 1.3600 | TP53 1.3523 | PHLDA3 1.3045 | BRCA2 1.2712 | C16orf5 1.2594 | STK11 1.1724 | BCL3 1.1329 | RRP8 1.1036 | IFI16 0.9032 | DYRK2 0.6555 | DDX5 0.3221 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
mechanoreceptor differentiation (boxplot) | 32 | 33 | 2.6963589662394742 | 0.0035051038114619626 | 0.04878533120156748 | 0.019943019943019943 | NTRK3 4.8124 | GPR98 4.6366 | HES1 3.7965 | PCDH15 3.5572 | CDH23 2.9737 | CUX1 2.2383 | JAG2 2.1763 | USH2A 2.0822 | GABRA5 2.0812 | VANGL2 2.0307 | LHFPL5 1.9424 | ATOH1 1.9203 | GRXCR1 1.8854 | FZD2 1.8049 | GABRB2 1.7081 | MYO7A 1.7012 | NOTCH1 1.6712 | CLIC5 1.6546 | FGFR1 1.5730 | JAG1 1.5613 | CTHRC1 1.4804 | HES5 1.4456 | NAGLU 1.4206 | LRTOMT 1.3465 | POU4F3 1.2812 | FGF20 1.2458 | DFNA5 1.1301 | BMP4 1.1081 | SOD1 0.8543 | USH1G 0.8160 | MCOLN3 0.4780 | STRC 0.4507 | WHRN | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of cell-substrate adhesion (boxplot) | 95 | 95 | 2.6959242291170553 | 0.0035096815874630094 | 0.04878533120156748 | 0.019886363636363636 | CDH13 3.9298 | CSF1 3.5095 | MACF1 3.3194 | NF2 3.2554 | CDKN2A 3.0353 | ATXN3 2.9275 | SPOCK1 2.7896 | VIT 2.7774 | UTRN 2.7531 | PRKCE 2.7354 | EPHA3 2.7107 | EPHA1 2.5465 | EDIL3 2.4754 | TACSTD2 2.4154 | FBLN2 2.3953 | CCR7 2.3166 | SERPINE1 2.3072 | ABI3BP 2.2421 | ARL2 2.2292 | ARHGAP6 2.1854 | BCL2 2.1766 | SPP1 2.1654 | SMAD3 2.1433 | FZD7 2.1227 | ROCK2 2.0790 | SEMA3E 2.0638 | EFNA5 2.0515 | NPNT 2.0460 | NID1 2.0430 | CDK6 2.0335 | WNT1 2.0180 | MYF5 1.9843 | MMP14 1.9618 | TEK 1.8630 | BCL6 1.8618 | TBCD 1.8480 | FOXF1 1.8463 | VTN 1.8442 | PIK3R1 1.8351 | VWC2 1.8282 | EGFLAM 1.8194 | TDGF1 1.8065 | PTPRO 1.7894 | PLEKHA2 1.6788 | NOTCH1 1.6712 | DMP1 1.6698 | APOD 1.6583 | CYR61 1.6494 | DDR1 1.6458 | ONECUT2 1.5906 | SMOC2 1.5879 | RASA1 1.5836 | CCDC80 1.5762 | PTPRJ 1.5709 | KDR 1.5543 | HSD17B12 1.5489 | COL8A1 1.5190 | COL1A1 1.4835 | CD36 1.4667 | MINK1 1.4611 | ANGPT2 1.4272 | ACER2 1.4118 | CASK 1.4083 | JAK2 1.4043 | PTEN 1.3846 | PTK2 1.3822 | GPM6B 1.3610 | NDNF 1.3563 | TSC1 1.3322 | PLG 1.3287 | RELL2 1.2916 | NF1 1.2913 | SDC4 1.2900 | SFRP1 1.2842 | CCL21 1.2605 | ONECUT1 1.2142 | TDGF1P3 1.2115 | GSK3B 1.1968 | PPM1F 1.1863 | ROCK1 1.1687 | SPOCK2 1.1539 | ILK 1.1347 | PTK2B 1.1280 | ITGB1 1.1192 | PIK3CB 0.9249 | LGALS1 0.9091 | ACVRL1 0.8961 | ITGA6 0.8763 | EMILIN1 0.8762 | EPB41L5 0.8760 | HOXA7 0.8607 | PLAU 0.8565 | ECM2 0.7676 | FZD4 0.7448 | THBS1 0.7292 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
behavioral fear response (boxplot) | 17 | 17 | 2.6912203193022504 | 0.003559558127519402 | 0.04912994635892599 | 0.0226628895184136 | GRIK2 3.2889 | NR2E1 2.8955 | GNG7 2.8840 | GRM7 2.8268 | GRIN2B 2.2951 | BCL2 2.1766 | CACNA1E 2.0970 | PENK 2.0828 | GABRA5 2.0812 | MAPK8IP2 1.8627 | DRD4 1.8319 | NEUROD2 1.8013 | DRD1 1.4777 | ALS2 1.3539 | VDAC1 1.3400 | MDK 1.2489 | CCK 0.9390 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
M band (boxplot) | 12 | 12 | 2.688890276599551 | 0.0035844989519997483 | 0.04933482219569231 | 0.022598870056497175 | ANK2 2.8691 | SPTBN1 2.7693 | SMPX 2.6933 | FHL2 2.6776 | MYOM1 2.5153 | TTN 2.4386 | ENO1 2.0766 | OBSCN 1.9276 | ANK1 1.7885 | SMTNL1 1.7062 | OBSL1 1.1569 | NBR1 0.7860 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
positive regulation of endocytosis (boxplot) | 69 | 70 | 2.6872429875489856 | 0.0036022261004897693 | 0.0494395413679579 | 0.022535211267605635 | BICD1 4.2108 | CAV1 3.7656 | HIP1 3.4696 | MAGI2 3.4637 | AMPH 3.4482 | VEGFA 3.0488 | NLGN1 2.7866 | PTX3 2.6077 | APOA5 2.5911 | CAMK1D 2.4333 | BIN1 2.3168 | NEDD4L 2.3099 | SERPINE1 2.3072 | TUB 2.3045 | PLD2 2.2800 | CALR 2.1592 | C3 2.0782 | SCYL2 2.0365 | MFGE8 2.0138 | ATAD1 2.0096 | SNCA 1.9846 | CBL 1.9784 | SFTPD 1.9782 | GAS6 1.9676 | TULP1 1.9365 | AZU1 1.9033 | GPC3 1.8708 | GH1 1.8449 | VTN 1.8442 | AHSG 1.8397 | MERTK 1.8314 | PPT1 1.7921 | ABR 1.7595 | ITGAV 1.7509 | SLC11A1 1.7405 | SYNJ2BP 1.7375 | SGIP1 1.7021 | GREM1 1.6695 | WNT3A 1.6407 | MIB1 1.6201 | F2RL1 1.6183 | DRD2 1.5853 | CALY 1.4903 | PCSK9 1.4808 | CD36 1.4667 | ACTN4 1.4437 | LDLRAP1 1.4279 | SFRP4 1.4173 | CLEC7A 1.3986 | BCR 1.3878 | CCL19 1.2605 | CCL21 | NCKAP1L 1.2593 | SELE 1.1773 | CBLL1 1.1540 | WASL 1.1528 | ANGPT1 1.1416 | CD63 1.1226 | ITGB1 1.1192 | MBL2 1.1098 | SPACA3 1.1041 | HNRNPK 1.0984 | CLIP3 0.9895 | AHI1 0.9870 | FCER1G 0.8951 | CD47 0.8677 | NOD2 0.6871 | CCL2 0.6763 | SYNJ1 0.6101 | GATA2 0.4907 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
caveola (boxplot) | 59 | 59 | 2.68470268512034 | 0.003629717590931225 | 0.04967731134254892 | 0.02247191011235955 | CDH13 3.9298 | CAV1 3.7656 | KCNMA1 3.3055 | ERBB4 3.2809 | INSR 3.1624 | CAV2 2.8160 | SCARB1 2.6205 | ADCYAP1R1 2.5080 | BMPR1A 2.4359 | IGF1R 2.4090 | CAV3 2.3881 | HMOX1 2.3654 | DLC1 2.2963 | PLD2 2.2800 | PTCH1 2.1082 | LRP6 2.0780 | BMPR2 2.0562 | EFNA5 2.0515 | SPRED1 1.9968 | PTGS2 1.9806 | CBL 1.9784 | FLOT2 1.9629 | MAPK1 1.9571 | CTSB 1.9372 | IRS1 1.9115 | MAPK3 1.8628 | SMO 1.8103 | FASLG 1.8023 | PTRF 1.7946 | MLC1 1.7589 | PLVAP 1.6992 | LRP8 1.6538 | NOS3 1.6288 | TRPC4 1.6274 | TGFBR2 1.5967 | SRC 1.5906 | SMPD2 1.5327 | HCK 1.4790 | DRD1 1.4777 | F2R 1.4291 | JAK2 1.4043 | MYOF 1.3837 | KIF18A 1.3361 | SLC27A1 1.3359 | CLN3 1.3063 | ATP1B3 1.2935 | FLOT1 1.2304 | LIPE 1.1888 | SELE 1.1773 | SLC2A1 1.1124 | TSC2 1.0731 | ADRBK1 1.0662 | ADRB2 1.0467 | SLC22A6 1.0441 | SDPR 1.0254 | ATP1B1 1.0200 | PTGIS 0.8316 | ATP1A2 0.4943 | HDAC6 0.1384 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
peptide biosynthetic process (boxplot) | 24 | 25 | 2.6842293573884146 | 0.0036348607661881305 | 0.04967731134254892 | 0.022408963585434174 | DMD 3.6492 | FURIN 3.4013 | BDH2 3.3649 | PCSK5 3.2644 | GCLM 3.0852 | HAGH 2.3782 | GGT1 2.3257 | GCLC 2.2372 | ALOX5AP 2.1705 | PCSK1 2.1639 | GGT5 2.0480 | MGST2 1.9981 | MRPS26 1.9195 | CNDP2 1.7699 | MGST3 1.5934 | GGT6 1.4984 | MRPS35 1.4422 | OPLAH 1.3145 | GSS 1.2798 | MRPS9 1.0659 | GGCT 0.9016 | GGT3P 0.8364 | LTC4S 0.5920 | GGT7 0.5763 | GGT2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
alpha-actinin binding (boxplot) | 12 | 12 | 2.68272795714075 | 0.003651218268471257 | 0.04969318233913805 | 0.0223463687150838 | MYPN 3.2513 | MAGI1 3.0941 | PTPRT 3.0314 | NRAP 2.7788 | PKD2L1 2.5895 | TTN 2.4386 | PDLIM2 2.3613 | PALLD 1.5733 | NPHS1 1.4983 | ITGB1 1.1192 | SYNPO2 0.9603 | DAG1 0.6937 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
regulation of lipid metabolic process (boxplot) | 191 | 198 | 2.6826042352703565 | 0.003652569138491879 | 0.04969318233913805 | 0.022284122562674095 | SIRT1 7.4176 | FGF19 4.0340 | CAV1 3.7656 | PRKAG2 3.7137 | FABP1 3.5813 | MLXIPL 3.3990 | ERBB4 3.2809 | C1QTNF2 3.0733 | TNF 3.0639 | APOA1 3.0248 | APOC3 | LPCAT1 3.0227 | PROX1 2.8868 | SIK1 2.8664 | LMF1 2.8542 | FLT3 2.7949 | PRKCE 2.7354 | SNAI2 2.6919 | FLT1 2.6297 | SCARB1 2.6205 | APOA4 2.5911 | APOA5 2.5911 | UGT1A7 2.5865 | UGT1A8 2.5865 | UGT1A9 | ABHD5 2.5629 | RBL2 2.5381 | PPARGC1A 2.4496 | TRIB3 2.4349 | ACACB 2.4178 | IGF1R 2.4090 | PLA2G4A 2.3298 | ADORA2B 2.3294 | CCR7 2.3166 | AGT 2.2659 | FGF1 2.2613 | PSAP 2.2453 | POR 2.2319 | ACSL1 2.2283 | CAB39L 2.1178 | AKT1 2.1144 | TWIST1 2.0979 | NR3C1 2.0926 | ABCG1 2.0741 | ACSL5 2.0627 | SNCA 1.9846 | PTGS2 1.9806 | IGF2 1.9742 | INS | VAV2 1.9727 | DRD3 1.9435 | UGT1A1 1.9423 | AGTR1 1.9300 | AVP 1.9195 | LDLR 1.9157 | IRS1 1.9115 | MID1IP1 1.8925 | BMP6 1.8906 | LSR 1.8819 | IL1B 1.8813 | NR5A1 1.8809 | CPT1B 1.8780 | BCL11B 1.8758 | PRKAA2 1.8703 | TEK 1.8630 | SREBF1 1.8466 | PIK3R1 1.8351 | DKK3 1.8337 | SCAP 1.8227 | IRS2 1.8084 | ANXA1 1.8032 | HRH1 1.7853 | AKT2 1.7769 | ZP3 1.7758 | PNPLA2 1.7743 | EPHA8 1.7658 | LHCGR 1.7607 | CREBL2 1.7565 | MTOR 1.7516 | NPC2 1.7277 | GHSR 1.7166 | PDE3B 1.7081 | ADORA1 1.7070 | BRCA1 1.7066 | HNF4A 1.7052 | ID2 1.6791 | PPARG 1.6692 | ABCD2 1.6687 | CIDEA 1.6633 | APOD 1.6583 | SORBS1 1.6523 | CYR61 1.6494 | PDGFRA 1.6489 | FITM2 1.6446 | REST 1.6316 | AKR1C3 1.6264 | CHRM5 1.6228 | TYSND1 1.6177 | CNR1 1.6061 | LYN 1.5986 | BMP2 1.5776 | BBS4 1.5605 | PDGFA 1.5347 | CPT2 1.5335 | CAB39 1.5334 | FBXW7 1.5194 | STAT5A 1.5114 | STAR 1.4812 | IL1A 1.4740 | GIMAP5 1.4739 | NFKB1 1.4613 | FGFR3 1.4587 | SEC14L2 1.4532 | APOE 1.4398 | GPAM 1.4378 | LDLRAP1 1.4279 | SF1 1.4220 | ACER1 1.4193 | ANGPTL3 1.4147 | KIT 1.4147 | LEP 1.4143 | NR1H4 1.4113 | SNAI1 1.3990 | PTK2 1.3822 | RBL1 1.3682 | LAMTOR1 1.3465 | APOC1 1.3441 | APOC2 | SLC27A1 1.3359 | ADIPOQ 1.3289 | NR1H3 1.3265 | CYP7A1 1.3148 | LONP2 1.3144 | HCAR2 1.2966 | ACADVL 1.2681 | CCL19 1.2605 | CCL21 | APOB 1.2451 | ACADL 1.2388 | PDGFRB 1.2307 | GAL 1.2052 | CPT1A 1.1834 | RB1 1.1822 | FGR 1.1781 | STRADB 1.1749 | ADRA2A 1.1742 | STK11 1.1724 | TSPO 1.1685 | NR1H2 1.1632 | GFI1 1.1568 | PPP2R5A 1.1534 | CYP17A1 1.1376 | CTDNEP1 1.1371 | FGFR4 1.1354 | DHCR7 1.1326 | PTK2B 1.1280 | FGF2 1.1278 | PRKAG1 1.1069 | CD81 1.0918 | CDC42 1.0907 | ATP1A1 1.0906 | PRKAB2 1.0760 | GPLD1 1.0747 | THRA 1.0727 | INSIG2 1.0701 | PRKAG3 1.0632 | STUB1 1.0527 | SERPINA3 1.0454 | PRKAB1 1.0322 | PPARA 1.0266 | PDGFB 1.0240 | PPAP2A 1.0217 | PRKCD 1.0164 | STAT5B 1.0063 | DHH 0.9994 | WNT4 0.9772 | TGFB1 0.9693 | AADAC 0.9668 | ARV1 0.9451 | STRADA 0.9421 | BMP5 0.9345 | APOA2 0.8951 | IFNG 0.8931 | SOD1 0.8543 | EDF1 0.8227 | MLYCD 0.8198 | EIF2AK3 0.7800 | PRKAA1 0.7726 | SLC25A20 0.7171 | THRSP 0.6885 | NOD2 0.6871 | PEX2 0.6819 | AVPR1A 0.6808 | INSIG1 0.6516 | CREB1 0.5390 | CNEP1R1 0.4915 | FRAP1 | LA16c-360B4.1 | |||||||||
vacuolar proton-transporting V-type ATPase complex (boxplot) | 11 | 12 | 2.680551394359755 | 0.0036750488386827485 | 0.049740411705828 | 0.022222222222222223 | ATP6V1D 5.0589 | ATP6V1G2 3.0639 | ATP6V1G2-DDX39B | ATP6V0D1 2.4205 | ATP6V1B1 2.1332 | ATP6V0D2 1.9877 | ATP6V1G1 1.8891 | ATP6V0A4 1.6520 | ZER1 1.5959 | ATP6V1F 1.5869 | ATP6V1H 1.5286 | ATP6V1G3 0.6241 |