data type: SNP
method: ZSCORE
K: 2
cutoff: 0.05
tolerance: 0%
Genes with the 1st to the k-th largest or smallest p-values: Exclude
Take common log and negated the p-values of genes: Yes

set name gene count set size z-score p-value corrected p-value FDR gene symbols
hsa04510
(boxplot)
1962026.2127589308343492.6031166111550874E-104.945921561194666E-80.0CRK
4.9972
COL11A2
4.6854
TNN
4.2700
CAV1
3.7656
FYN
3.7055
GRB2
3.5564
PDGFD
3.4500
MYLK
3.2871
ERBB2
3.2295
PARVA
3.2150
MAPK9
3.1472
ACTN3
3.1352
VEGFA
3.0488
TNR
3.0413
PRKCB
2.9939
PAK7
2.9767
VEGFB
2.9601
RASGRF1
2.9288
LAMA3
2.9086
TLN2
2.8514
COL4A2
2.8351
CAV2
2.8160
EGFR
2.8090
COL6A2
2.7393
PARVG
2.7255
PDGFC
2.6869
ITGA2
2.6856
PARVB
2.6643
HRAS
2.6539
FLT1
2.6297
PPP1CB
2.6090
PIK3CD
2.5941
COL4A1
2.5872
PIK3CG
2.5697
ITGA1
2.5638
ZYX
2.5465
ITGA9
2.5201
THBS2
2.4552
IGF1R
2.4090
CAV3
2.3881
LAMA5
2.3426
CRKL
2.3083
RAP1A
2.2806
RELN
2.2249
CCND3
2.2241
LAMA2
2.2226
EGF
2.1937
BCL2
2.1766
ITGB3
2.1729
PRKCA
2.1719
SPP1
2.1654
CCND2
2.1625
MAPK8
2.1614
ACTB
2.1337
TNXB
2.1180
COL6A1
2.1167
AKT1
2.1144
MYL10
2.1111
ROCK2
2.0790
ITGB5
2.0784
LAMB1
2.0735
MAPK10
2.0583
DOCK1
2.0545
LAMA4
2.0531
ACTN1
2.0386
MYL7
2.0341
LAMB3
2.0178
ITGA10
2.0120
PIK3R3
2.0057
VAV2
1.9727
CCND1
1.9690
PAK4
1.9647
BRAF
1.9582
MAPK1
1.9571
PPP1R12A
1.9556
PRKCG
1.9540
ITGA8
1.9537
FN1
1.9294
LAMC1
1.9271
ITGB6
1.9218
RAC1
1.9125
TNC
1.9083
COL5A1
1.9082
ACTG1
1.9056
RHOA
1.8947
JUN
1.8868
RAPGEF1
1.8760
MAPK3
1.8628
COL6A3
1.8501
VTN
1.8442
SHC4
1.8427
VAV3
1.8406
PIK3R1
1.8351
LAMC2
1.8307
THBS3
1.8194
ARHGAP5
1.8010
RAP1B
1.7908
PAK6
1.7907
PIK3R5
1.7900
AKT2
1.7769
ITGAV
1.7509
PIP5K1C
1.7353
THBS4
1.7325
SHC2
1.7321
LAMA1
1.7275
MYLK3
1.7219
ACTN2
1.7215
ITGA11
1.7210
VCL
1.7125
RAF1
1.7090
PAK2
1.7086
MYL9
1.7057
ELK1
1.6910
COL6A6
1.6842
ITGA4
1.6794
BAD
1.6791
COL4A4
1.6590
LAMB4
1.6528
PDGFRA
1.6489
BCAR1
1.6063
IGF1
1.6014
SRC
1.5906
MYL12A
1.5886
MYL12B
FLNC
1.5869
VEGFC
1.5569
KDR
1.5543
FLNB
1.5528
MYL2
1.5502
MAP2K1
1.5376
ITGA2B
1.5355
PDGFA
1.5347
SOS2
1.5227
IBSP
1.5119
LAMB2
1.4979
COL1A1
1.4835
COL3A1
1.4690
COL5A2
1.4504
ACTN4
1.4437
COL11A1
1.4339
SHC3
1.4335
AKT3
1.4293
PDPK1
1.4292
COL1A2
1.4123
VWF
1.4032
CAPN2
1.3921
BIRC2
1.3909
BIRC3
VAV1
1.3902
PTEN
1.3846
PTK2
1.3822
DIAPH1
1.3602
VASP
1.3560
COL5A3
1.3492
COL4A6
1.3398
PIK3CA
1.3325
ITGA3
1.3270
COL2A1
1.3191
PPP1CA
1.3052
SHC1
1.2933
FLT4
1.2760
PIK3R2
1.2583
CHAD
1.2469
HGF
1.2321
PDGFRB
1.2307
GSK3B
1.1968
ITGB7
1.1840
LAMC3
1.1743
ROCK1
1.1687
SOS1
1.1496
MET
1.1441
PAK1
1.1424
ILK
1.1347
ITGA7
1.1296
ITGB1
1.1192
FIGF
1.1079
MYLK2
1.0997
RAC2
1.0961
CDC42
1.0907
PDGFB
1.0240
PPP1CC
1.0164
PXN
1.0115
COMP
1.0103
TLN1
0.9695
FLNA
0.9266
PIK3CB
0.9249
ITGB4
0.8918
RAC3
0.8880
ITGB8
0.8819
PAK3
0.8800
ITGA6
0.8763
ITGA5
0.8380
PGF
0.7441
THBS1
0.7292
XIAP
0.7016
MYL5
0.6911
CTNNB1
0.5466
MYLPF
0.4455
Focal adhesion
646048
646821
GRLF1
hsa04012
(boxplot)
87884.4138007971237025.078571293726242E-64.8246427290399296E-40.0CRK
4.9972
GRB2
3.5564
MAP2K2
3.3627
ERBB4
3.2809
ERBB2
3.2295
MAPK9
3.1472
MAP2K7
3.0946
PRKCB
2.9939
PAK7
2.9767
EGFR
2.8090
HRAS
2.6539
PIK3CD
2.5941
PIK3CG
2.5697
CAMK2D
2.5615
NRG3
2.5461
PLCG2
2.4205
CRKL
2.3083
CAMK2B
2.2519
EGF
2.1937
NRG1
2.1819
CAMK2G
2.1818
PRKCA
2.1719
MAPK8
2.1614
NRG2
2.1614
CAMK2A
2.1496
GAB1
2.1327
AKT1
2.1144
MAPK10
2.0583
PIK3R3
2.0057
CBL
1.9784
PAK4
1.9647
BRAF
1.9582
MYC
1.9575
MAPK1
1.9571
PRKCG
1.9540
BTC
1.9365
RPS6KB2
1.9131
JUN
1.8868
AREG
1.8790
MAPK3
1.8628
SHC4
1.8427
PIK3R1
1.8351
MAP2K4
1.8266
PAK6
1.7907
PIK3R5
1.7900
NRG4
1.7795
AKT2
1.7769
CBLB
1.7575
ABL2
1.7537
MTOR
1.7516
SHC2
1.7321
RAF1
1.7090
PAK2
1.7086
ELK1
1.6910
BAD
1.6791
TGFA
1.6583
EIF4EBP1
1.6002
SRC
1.5906
CBLC
1.5609
MAP2K1
1.5376
CDKN1A
1.5286
SOS2
1.5227
STAT5A
1.5114
NCK2
1.4470
HBEGF
1.4417
ABL1
1.4403
SHC3
1.4335
AKT3
1.4293
ARAF
1.3834
PTK2
1.3822
PIK3CA
1.3325
SHC1
1.2933
PIK3R2
1.2583
RPS6KB1
1.2260
GSK3B
1.1968
PLCG1
1.1759
CDKN1B
1.1519
SOS1
1.1496
PAK1
1.1424
ERBB3
1.0409
STAT5B
1.0063
KRAS
0.9975
NRAS
0.9279
PIK3CB
0.9249
PAK3
0.8800
EREG
0.8038
NCK1
0.7460
ErbB signaling pathway
hsa04270
(boxplot)
1151174.20949358158427961.2797185636959085E-58.104884236740755E-40.0CYP4A22
3.4215
MAP2K2
3.3627
KCNMA1
3.3055
MYLK
3.2871
ACTA2
3.1316
PRKCB
2.9939
PLA2G4E
2.9874
PLCB3
2.9532
PRKACB
2.9293
CACNA1C
2.8754
PRKCE
2.7354
ADRA1D
2.6991
PRKX
2.6609
KCNMB2
2.6357
PLCB1
2.6151
PPP1CB
2.6090
ADCY5
2.5811
ADCY2
2.5386
GUCY1B3
2.5107
JMJD7-PLA2G4B
2.4987
PLA2G4B
PRKG1
2.4878
GUCY1A3
2.4867
PPP1R14A
2.4493
KCNMB3
2.4149
MRVI1
2.3945
PLA2G5
2.3447
GNA12
2.3370
PLA2G12B
2.3313
PLA2G4A
2.3298
ADORA2B
2.3294
MYH11
2.2753
CALD1
2.2528
PLA2G2E
2.2318
PRKCH
2.1900
PRKCA
2.1719
ADCY3
2.1650
ADRA1A
2.1619
ITPR2
2.1594
CACNA1D
2.1182
AVPR1B
2.0938
ROCK2
2.0790
ARHGEF11
2.0462
RAMP3
1.9727
BRAF
1.9582
MAPK1
1.9571
GUCY1A2
1.9560
PPP1R12A
1.9556
PRKCG
1.9540
MYL6
1.9522
MYL6B
1.9522
KCNMB4
1.9400
AGTR1
1.9300
RHOA
1.8947
PLCB2
1.8631
MAPK3
1.8628
CALCRL
1.8557
CALML5
1.7832
PLA2G10
1.7764
ITPR3
1.7657
CALML3
1.7646
PLA2G3
1.7635
PRKACG
1.7616
GNAQ
1.7558
PLA2G2A
1.7465
ADCY9
1.7405
ADCY1
1.7392
MYLK3
1.7219
ADCY8
1.7139
RAF1
1.7090
MYL9
1.7057
CYP4A11
1.6857
CALML6
1.6066
GNA13
1.6039
MAP2K1
1.5376
PRKCQ
1.5129
ADRA1B
1.4817
PLA2G2F
1.4746
RAMP1
1.4694
ADCY4
1.4548
ITPR1
1.4342
ADCY7
1.4224
PLA2G6
1.3992
CACNA1S
1.3954
ARAF
1.3834
CALM1
1.3829
PLCB4
1.3630
GNA11
1.3379
NPR1
1.3340
PPP1CA
1.3052
ADORA2A
1.3027
ARHGEF12
1.2882
PPP1R12B
1.2651
PLA2G2D
1.2175
GNAS
1.1857
ROCK1
1.1687
CALM2
1.1102
PLA2G12A
1.1051
MYLK2
1.0997
KCNU1
1.0750
KCNMB1
1.0743
PPP1CC
1.0164
PRKCD
1.0164
ACTG2
1.0149
CACNA1F
0.9583
NPR2
0.9581
RAMP2
0.9523
ARHGEF1
0.8908
CALM3
0.8371
PTGIR
0.8371
EDNRA
0.8058
PLA2G2C
0.7622
ADCY6
0.7536
PRKACA
0.6979
AVPR1A
0.6808
PLA2G1B
0.4953
Vascular smooth muscle contraction
hsa04360
(boxplot)
1281304.1031668292203692.037665817478107E-59.678912633021008E-40.0SEMA5A
7.2758
DCC
5.1066
UNC5C
4.2710
FYN
3.7055
SEMA4B
3.5707
SLIT1
3.2641
EPHA6
3.2448
PPP3R2
3.1467
FES
3.1088
ROBO2
3.0085
PAK7
2.9767
LRRC4C
2.9758
NFATC2
2.9629
SLIT2
2.8500
SEMA6A
2.7685
PLXNB2
2.7490
EPHA3
2.7107
EPHB2
2.7088
ABLIM2
2.6700
HRAS
2.6539
CFL2
2.6485
EPHB1
2.6334
UNC5D
2.5801
CXCL12
2.5696
EPHA1
2.5465
SRGAP2
2.5232
SLIT3
2.4489
PPP3CB
2.4174
RGS3
2.3400
SEMA5B
2.3269
PLXNC1
2.3225
NFATC4
2.2770
ABLIM1
2.2765
SRGAP1
2.2338
RHOD
2.2060
EPHA5
2.1737
UNC5B
2.1685
ROBO1
2.1673
NFATC1
2.1519
ROCK2
2.0790
SEMA3E
2.0638
NTNG1
2.0564
EFNA5
2.0515
PLXNA2
2.0455
SEMA3D
2.0149
EFNB2
1.9944
PAK4
1.9647
MAPK1
1.9571
PPP3CC
1.9488
PPP3R1
1.9487
RAC1
1.9125
NFATC3
1.9050
SEMA6C
1.9049
RHOA
1.8947
MAPK3
1.8628
SEMA3G
1.8440
PAK6
1.7907
EPHA8
1.7658
EFNA4
1.7569
PAK2
1.7086
EPHA7
1.6962
NTN4
1.6953
SEMA3A
1.6808
EPHA4
1.6721
SRGAP3
1.6565
DPYSL2
1.6469
GNAI1
1.6302
NRP1
1.5851
RASA1
1.5836
SEMA4C
1.5761
CDK5
1.5715
SEMA6B
1.5688
ROBO3
1.5671
LIMK2
1.5338
SEMA6D
1.4938
CHP2
1.4539
NCK2
1.4470
GNAI3
1.4435
ABL1
1.4403
PPP3CA
1.4235
EPHB4
1.4218
SEMA4D
1.3860
PTK2
1.3822
NGEF
1.3111
ARHGEF12
1.2882
EFNB3
1.2849
UNC5A
1.2805
CFL1
1.2636
CXCR4
1.2607
EFNA1
1.2501
SEMA3F
1.2271
SEMA4F
1.2167
PLXNA3
1.2147
NTN1
1.2089
GSK3B
1.1968
PLXNB3
1.1942
LIMK1
1.1825
SEMA3C
1.1792
EPHA2
1.1715
ROCK1
1.1687
MET
1.1441
PAK1
1.1424
ITGB1
1.1192
RAC2
1.0961
CDC42
1.0907
EFNA3
1.0625
KRAS
0.9975
ABLIM3
0.9803
EFNB1
0.9761
EFNA2
0.9726
NRAS
0.9279
RAC3
0.8880
PAK3
0.8800
RND1
0.8600
NTN3
0.7689
DPYSL5
0.7538
NCK1
0.7460
SEMA4G
0.7362
SEMA7A
0.7223
NFAT5
0.7008
SEMA4A
0.6729
EPHB6
0.6660
PLXNB1
0.6552
EPHB3
0.6149
L1CAM
0.6002
GNAI2
0.5640
SEMA3B
0.5640
PLXNA1
0.4156
Axon guidance
CHP
hsa04722
(boxplot)
1261274.08586020059030552.1956907454545593E-59.678912633021008E-40.0CRK
4.9972
NTRK3
4.8124
YWHAE
4.5001
GRB2
3.5564
MAP2K2
3.3627
NTF4
3.2839
MAP3K5
3.1884
MAPK9
3.1472
MAP2K7
3.0946
BAX
3.0299
MAP2K5
2.8555
NTRK2
2.7766
RPS6KA1
2.6847
HRAS
2.6539
NGFRAP1
2.6339
YWHAH
2.6079
PIK3CD
2.5941
PIK3CG
2.5697
CAMK2D
2.5615
FRS2
2.5419
RPS6KA2
2.5126
CAMK4
2.5094
PLCG2
2.4205
NFKBIA
2.3376
ARHGDIB
2.3147
CRKL
2.3083
RAP1A
2.2806
NGFR
2.2572
CAMK2B
2.2519
CAMK2G
2.1818
BCL2
2.1766
MAPK8
2.1614
CAMK2A
2.1496
TP73
2.1456
NFKBIB
2.1358
GAB1
2.1327
AKT1
2.1144
PTPN11
2.0897
KIDINS220
2.0695
FOXO3
2.0675
MAPK10
2.0583
NTRK1
2.0462
NGF
2.0438
PIK3R3
2.0057
MAP3K1
1.9924
IRAK3
1.9617
BRAF
1.9582
IRAK4
1.9582
MAPK1
1.9571
RAC1
1.9125
IRS1
1.9115
RHOA
1.8947
JUN
1.8868
RAPGEF1
1.8760
MAPK3
1.8628
MAPK7
1.8453
SHC4
1.8427
PIK3R1
1.8351
IRS2
1.8084
FASLG
1.8023
YWHAZ
1.7916
RAP1B
1.7908
PIK3R5
1.7900
CALML5
1.7832
AKT2
1.7769
CALML3
1.7646
SHC2
1.7321
RAF1
1.7090
IRAK2
1.7090
BAD
1.6791
RELA
1.6587
RPS6KA4
1.6294
CALML6
1.6066
RPS6KA5
1.5702
MAP2K1
1.5376
SOS2
1.5227
PDK1
1.4872
YWHAQ
1.4680
NFKB1
1.4613
RIPK2
1.4586
ABL1
1.4403
SHC3
1.4335
AKT3
1.4293
CALM1
1.3829
RPS6KA3
1.3752
SH2B2
1.3733
TP53
1.3523
PIK3CA
1.3325
SHC1
1.2933
PIK3R2
1.2583
BDNF
1.2240
MAGED1
1.2092
GSK3B
1.1968
PRDM4
1.1811
PLCG1
1.1759
NFKBIE
1.1735
SOS1
1.1496
SORT1
1.1418
RPS6KA6
1.1135
MAPKAPK2
1.1133
YWHAG
1.1107
CALM2
1.1102
TRAF6
1.1053
IRAK1
1.0945
CDC42
1.0907
CSK
1.0827
YWHAB
1.0405
PSEN1
1.0274
IRS4
1.0252
PRKCD
1.0164
KRAS
0.9975
ZNF274
0.9964
NTF3
0.9832
MAPK14
0.9700
ATF4
0.9491
MAP3K3
0.9421
NRAS
0.9279
PIK3CB
0.9249
SH2B1
0.8855
SH2B3
0.8791
MAPK11
0.8399
MAPK12
0.8399
CALM3
0.8371
IKBKB
0.7521
ARHGDIA
0.6161
MAPK13
0.6142
Neurotrophin signaling pathway
hsa04720
(boxplot)
69713.72345856186873649.82560635551799E-50.0031114420125806970.0MAP2K2
3.3627
PPP3R2
3.1467
PRKCB
2.9939
PLCB3
2.9532
PRKACB
2.9293
CACNA1C
2.8754
RPS6KA1
2.6847
PRKX
2.6609
HRAS
2.6539
RAPGEF3
2.6418
PLCB1
2.6151
PPP1CB
2.6090
CAMK2D
2.5615
RPS6KA2
2.5126
CAMK4
2.5094
PPP3CB
2.4174
GRIN2B
2.2951
RAP1A
2.2806
CAMK2B
2.2519
CAMK2G
2.1818
PRKCA
2.1719
ITPR2
2.1594
CAMK2A
2.1496
GRIN2A
2.0931
GRM5
1.9765
GRIN2C
1.9757
BRAF
1.9582
MAPK1
1.9571
PPP1R12A
1.9556
PRKCG
1.9540
PPP3CC
1.9488
PPP3R1
1.9487
PLCB2
1.8631
MAPK3
1.8628
RAP1B
1.7908
CALML5
1.7832
ITPR3
1.7657
CALML3
1.7646
PRKACG
1.7616
GNAQ
1.7558
ADCY1
1.7392
ADCY8
1.7139
CREBBP
1.7131
RAF1
1.7090
GRM1
1.6533
CALML6
1.6066
MAP2K1
1.5376
EP300
1.4888
CHP2
1.4539
ITPR1
1.4342
PPP1R1A
1.4284
PPP3CA
1.4235
ARAF
1.3834
CALM1
1.3829
GRIN2D
1.3766
RPS6KA3
1.3752
PLCB4
1.3630
PPP1CA
1.3052
GRIN1
1.2637
GRIA1
1.1475
RPS6KA6
1.1135
CALM2
1.1102
PPP1CC
1.0164
KRAS
0.9975
GRIA2
0.9514
ATF4
0.9491
NRAS
0.9279
CALM3
0.8371
PRKACA
0.6979
Long-term potentiation
CHP
hsa04070
(boxplot)
78793.65984381573249261.2618451131340969E-40.003425008164221120.0INPP1
4.0268
PIK3C2G
3.7146
INPP5K
3.5378
DGKI
3.4965
INPP5D
3.1650
PRKCB
2.9939
DGKG
2.9578
PLCB3
2.9532
ITPKB
2.8294
DGKZ
2.8053
SYNJ2
2.7782
DGKB
2.6459
PLCB1
2.6151
PIK3CD
2.5941
PIK3CG
2.5697
CDIPT
2.5282
PI4KA
2.5044
ITPKA
2.4578
PLCG2
2.4205
INPPL1
2.4159
PRKCA
2.1719
ITPR2
2.1594
PIP5K1A
2.0835
DGKH
2.0482
PIP4K2B
2.0331
PLCE1
2.0072
PIK3R3
2.0057
OCRL
2.0031
PRKCG
1.9540
IMPA2
1.9254
ITPK1
1.8685
PLCB2
1.8631
PIK3R1
1.8351
PIP4K2A
1.8178
INPP5A
1.8055
PIK3R5
1.7900
CALML5
1.7832
PIP5K1B
1.7709
ITPR3
1.7657
CALML3
1.7646
INPP5J
1.7635
PIP5K1C
1.7353
PI4KB
1.7345
CALML6
1.6066
CDS2
1.6034
PI4K2A
1.5996
INPP4B
1.5917
DGKA
1.5908
DGKD
1.5653
DGKQ
1.5429
INPP4A
1.5233
PI4K2B
1.4349
ITPR1
1.4342
PIK3C2B
1.3906
PTEN
1.3846
CALM1
1.3829
PLCB4
1.3630
PLCD3
1.3431
PIK3CA
1.3325
IPPK
1.3039
PLCD4
1.2779
PLCD1
1.2638
PIK3R2
1.2583
PLCG1
1.1759
PIKFYVE
1.1741
IMPA1
1.1622
PIP4K2C
1.1372
CALM2
1.1102
INPP5B
1.1013
INPP5E
1.0413
CDS1
1.0042
DGKE
0.9862
PIK3CB
0.9249
PIK3C2A
0.8669
CALM3
0.8371
PIK3C3
0.7608
SYNJ1
0.6101
PLCZ1
0.4867
Phosphatidylinositol signaling system
hsa04020
(boxplot)
1751793.6551588546175811.2851138981950783E-40.003425008164221120.0MYLK
3.2871
HTR7
3.2865
ERBB4
3.2809
ERBB2
3.2295
RYR2
3.1737
TNNC2
3.1678
PPP3R2
3.1467
GNAL
3.0690
CACNA1G
3.0242
PRKCB
2.9939
PLCB3
2.9532
PRKACB
2.9293
CACNA1C
2.8754
ATP2B2
2.8342
ITPKB
2.8294
HTR4
2.8101
EGFR
2.8090
SLC8A1
2.7718
ADRA1D
2.6991
PRKX
2.6609
PLCB1
2.6151
RYR3
2.5711
CAMK2D
2.5615
ADCY2
2.5386
CAMK4
2.5094
ITPKA
2.4578
CACNA1H
2.4410
PLCG2
2.4205
PPP3CB
2.4174
BDKRB2
2.4033
OXTR
2.3881
P2RX5
2.3388
ADORA2B
2.3294
NOS1
2.3035
ATP2B4
2.2998
CAMK2B
2.2519
PDE1C
2.1963
CAMK2G
2.1818
PRKCA
2.1719
ADCY3
2.1650
ADRA1A
2.1619
ITPR2
2.1594
CAMK2A
2.1496
CACNA1D
2.1182
TACR2
2.0981
CACNA1E
2.0970
AVPR1B
2.0938
GRIN2A
2.0931
GNA14
2.0910
CCKAR
2.0865
PLCE1
2.0072
GRM5
1.9765
GRIN2C
1.9757
PRKCG
1.9540
P2RX1
1.9501
PPP3CC
1.9488
PPP3R1
1.9487
CHRM3
1.9459
CACNA1A
1.9305
HTR2B
1.9303
AGTR1
1.9300
SLC8A3
1.9072
SPHK2
1.8974
GNA15
1.8776
CYSLTR1
1.8716
CHRM2
1.8694
PLCB2
1.8631
P2RX7
1.8574
CD38
1.8553
CACNA1B
1.8481
TNNC1
1.8440
VDAC3
1.8137
EDNRB
1.7889
HRH1
1.7853
CALML5
1.7832
TRHR
1.7830
ITPR3
1.7657
CALML3
1.7646
PRKACG
1.7616
LHCGR
1.7607
GNAQ
1.7558
ADCY9
1.7405
ADCY1
1.7392
TBXA2R
1.7383
MYLK3
1.7219
ATP2B3
1.7173
HRH2
1.7143
ADCY8
1.7139
ATP2A2
1.6834
CHRNA7
1.6719
BST1
1.6663
GRM1
1.6533
PDGFRA
1.6489
PTAFR
1.6452
NOS3
1.6288
CHRM5
1.6228
CACNA1I
1.6100
CALML6
1.6066
ADRB1
1.6047
HTR2A
1.5850
RYR1
1.5561
PTGER1
1.5412
PDE1A
1.5160
P2RX4
1.5095
SPHK1
1.5010
PHKG2
1.4975
SLC8A2
1.4933
HTR5A
1.4880
ADRA1B
1.4817
DRD1
1.4777
ADCY4
1.4548
CHP2
1.4539
VDAC2
1.4467
ITPR1
1.4342
F2R
1.4291
PPP3CA
1.4235
ADCY7
1.4224
CACNA1S
1.3954
CALM1
1.3829
LTB4R2
1.3819
P2RX3
1.3783
GRIN2D
1.3766
PLCB4
1.3630
ATP2A1
1.3612
TACR1
1.3533
CCKBR
1.3511
HTR6
1.3475
PTGFR
1.3436
PLCD3
1.3431
VDAC1
1.3400
GNA11
1.3379
ADRB3
1.3060
ADORA2A
1.3027
NOS2
1.3024
DRD5
1.2989
TACR3
1.2920
PLCD4
1.2779
PLCD1
1.2638
GRIN1
1.2637
PTGER3
1.2521
PDGFRB
1.2307
GRPR
1.2039
GNAS
1.1857
PDE1B
1.1847
PLCG1
1.1759
NTSR1
1.1495
PPID
1.1303
PTK2B
1.1280
SLC25A4
1.1125
CALM2
1.1102
MYLK2
1.0997
CYSLTR2
1.0547
ADRB2
1.0467
CHRM1
1.0409
ERBB3
1.0409
BDKRB1
1.0309
PHKG1
1.0042
ATP2A3
0.9855
TRPC1
0.9629
CACNA1F
0.9583
HTR2C
0.9475
ATP2B1
0.9361
PLN
0.9193
PHKA1
0.8977
PHKA2
0.8769
CALM3
0.8371
SLC25A31
0.8219
PHKB
0.8149
EDNRA
0.8058
P2RX6
0.7959
SLC25A5
0.7291
PRKACA
0.6979
AVPR1A
0.6808
P2RX2
0.6514
PLCZ1
0.4867
Calcium signaling pathway
CHP
LOC729317
SLC25A6
hsa00564
(boxplot)
78803.60874136645434351.5384308316801487E-40.003425008164221120.0PCYT1B
7.2283
LPGAT1
4.8079
DGKI
3.4965
CRLS1
3.3398
LPCAT1
3.0227
PLA2G4E
2.9874
DGKG
2.9578
DGKZ
2.8053
CHAT
2.7603
GPD1
2.7351
DGKB
2.6459
PTDSS2
2.6333
AGPAT4
2.5633
CDIPT
2.5282
GPAT2
2.5064
JMJD7-PLA2G4B
2.4987
PLA2G4B
PLA2G5
2.3447
PLA2G12B
2.3313
PLA2G4A
2.3298
PLD2
2.2800
PLA2G2E
2.2318
LCAT
2.1598
LCLAT1
2.1535
CHPT1
2.0903
MBOAT2
2.0695
DGKH
2.0482
AGPAT6
2.0214
AGPAT2
2.0126
PLA2G15
1.9050
CHKB
1.8780
PCYT1A
1.8010
ETNK1
1.7911
PLA2G10
1.7764
PLD1
1.7651
PLA2G3
1.7635
PLA2G2A
1.7465
PISD
1.7331
AGPAT3
1.7230
PEMT
1.6828
LPCAT2
1.6530
CDS2
1.6034
AGPAT1
1.5913
DGKA
1.5908
DGKD
1.5653
DGKQ
1.5429
MBOAT1
1.5326
MBOAT7
1.5216
PLA2G2F
1.4746
PPAP2B
1.4601
LPCAT3
1.4556
GPAM
1.4378
CEPT1
1.4168
PLA2G6
1.3992
LYPLA1
1.3969
LPCAT4
1.3776
EPT1
1.2808
CHKA
1.2791
PLA2G2D
1.2175
PHOSPHO1
1.2170
GNPAT
1.2058
PTDSS1
1.1676
C17orf48
1.1438
ETNK2
1.1374
GPD2
1.1148
PGS1
1.1094
PLA2G12A
1.1051
TAZ
1.0762
GPD1L
1.0398
PPAP2A
1.0217
CDS1
1.0042
DGKE
0.9862
PPAP2C
0.9653
ACHE
0.9394
PCYT2
0.7654
PLA2G2C
0.7622
LYPLA2
0.6708
AGPAT9
0.6685
PLA2G1B
0.4953
Glycerophospholipid metabolism
hsa05416
(boxplot)
67763.47022336574118562.600128557317394E-40.0049402442589030480.0HLA-DMA
4.6143
HLA-DOA
4.4996
CAV1
3.7656
FYN
3.7055
DMD
3.6492
EIF4G1
3.5399
SGCG
3.0172
BID
2.7152
HLA-DMB
2.6120
ITGB2
2.5057
CD40
2.4680
HLA-DQA1
2.3613
CASP3
2.3272
SGCD
2.3072
HLA-F
2.2828
MYH11
2.2753
LAMA2
2.2226
CXADR
2.1888
CD28
2.1569
HLA-DRB1
2.1516
ACTB
2.1337
EIF4G3
2.0618
CD80
1.9711
CCND1
1.9690
CD86
1.9313
RAC1
1.9125
ACTG1
1.9056
SGCB
1.8841
HLA-DRB5
1.8305
MYH6
1.8142
MYH7
1.8142
SGCA
1.7693
ABL2
1.7537
HLA-DQB1
1.7437
MYH15
1.7006
ICAM1
1.6718
HLA-B
1.6543
HLA-DOB
1.5897
CASP9
1.5727
HLA-DQA2
1.5353
HLA-G
1.5161
MYH1
1.5065
MYH2
1.5065
MYH10
1.4980
HLA-DPA1
1.4883
HLA-DPB1
MYH14
1.4431
ABL1
1.4403
HLA-A
ITGAL
1.3652
MYH7B
1.2798
HLA-DRA
1.2787
HLA-E
1.2721
HLA-DRB3
1.2503
CYCS
1.1994
CASP8
1.1822
MYH13
1.1562
MYH4
1.1555
MYH8
1.1555
MYH9
1.1496
HLA-C
1.1295
RAC2
1.0961
MYH3
1.0276
CD55
0.9660
RAC3
0.8880
PRF1
0.7335
DAG1
0.6937
EIF4G2
0.5813
CD40LG
0.3570
Viral myocarditis
100294318
646048
646821
HLA-DRB4
LOC100133583
LOC652614
hsa04664
(boxplot)
78803.4281322419646333.0387466786163664E-40.0052487442630646330.1BTK
4.4391
FYN
3.7055
MAP2K6
3.6149
GRB2
3.5564
MAP2K2
3.3627
INPP5D
3.1650
MAPK9
3.1472
MAP2K7
3.0946
TNF
3.0639
PRKCB
2.9939
PLA2G4E
2.9874
LAT
2.8728
PRKCE
2.7354
HRAS
2.6539
PIK3CD
2.5941
PIK3CG
2.5697
JMJD7-PLA2G4B
2.4987
PLA2G4B
PLCG2
2.4205
PLA2G5
2.3447
PLA2G12B
2.3313
PLA2G4A
2.3298
PLA2G2E
2.2318
GAB2
2.2298
PRKCA
2.1719
MAPK8
2.1614
SYK
2.1149
AKT1
2.1144
MAPK10
2.0583
PIK3R3
2.0057
VAV2
1.9727
MAPK1
1.9571
RAC1
1.9125
MAPK3
1.8628
VAV3
1.8406
PIK3R1
1.8351
MAP2K4
1.8266
PIK3R5
1.7900
AKT2
1.7769
PLA2G10
1.7764
PLA2G3
1.7635
PLA2G2A
1.7465
RAF1
1.7090
IL4
1.6202
LYN
1.5986
MAP2K1
1.5376
SOS2
1.5227
PDK1
1.4872
PLA2G2F
1.4746
AKT3
1.4293
MS4A2
1.4184
PLA2G6
1.3992
VAV1
1.3902
PIK3CA
1.3325
IL5
1.2733
PIK3R2
1.2583
PLA2G2D
1.2175
PLCG1
1.1759
SOS1
1.1496
PLA2G12A
1.1051
RAC2
1.0961
FCER1A
1.0656
PRKCD
1.0164
KRAS
0.9975
CSF2
0.9905
IL3
0.9905
MAPK14
0.9700
LCP2
0.9459
NRAS
0.9279
PIK3CB
0.9249
FCER1G
0.8951
RAC3
0.8880
MAPK11
0.8399
MAPK12
0.8399
IL13
0.8304
PLA2G2C
0.7622
MAPK13
0.6142
MAP2K3
0.5826
PLA2G1B
0.4953
Fc epsilon RI signaling pathway
hsa05412
(boxplot)
74773.3234895671100564.4449373994703834E-40.007037817549161440.09090909090909091CDH2
3.9744
DMD
3.6492
RYR2
3.1737
CTNNA3
3.1603
CACNB4
3.1376
ACTN3
3.1352
SGCG
3.0172
CACNA1C
2.8754
SLC8A1
2.7718
ITGA2
2.6856
CACNG3
2.6709
ITGA1
2.5638
ITGA9
2.5201
DSG2
2.5192
CTNNA2
2.3669
TCF7L1
2.3158
SGCD
2.3072
CACNG4
2.2546
LAMA2
2.2226
CACNB2
2.2123
ITGB3
2.1729
ACTB
2.1337
CACNA1D
2.1182
TCF7L2
2.0892
ITGB5
2.0784
ACTN1
2.0386
ITGA10
2.0120
CACNA2D1
1.9982
CACNA2D3
1.9648
CACNG7
1.9540
ITGA8
1.9537
ITGB6
1.9218
ACTG1
1.9056
JUP
1.9019
SGCB
1.8841
CACNG1
1.8336
SGCA
1.7693
ITGAV
1.7509
LEF1
1.7470
ACTN2
1.7215
ITGA11
1.7210
CACNA2D2
1.6959
CACNG6
1.6930
ATP2A2
1.6834
ITGA4
1.6794
CACNG5
1.6745
DSC2
1.6288
ITGA2B
1.5355
GJA1
1.5265
ACTN4
1.4437
CACNA2D4
1.4192
CACNA1S
1.3954
CACNG2
1.3692
CTNNA1
1.3657
DES
1.3358
ITGA3
1.3270
PKP2
1.2815
CACNG8
1.2699
ITGB7
1.1840
CACNB1
1.1775
ITGA7
1.1296
ITGB1
1.1192
LMNA
1.0722
DSP
1.0262
CACNA1F
0.9583
ITGB4
0.8918
ITGB8
0.8819
ITGA6
0.8763
ITGA5
0.8380
CACNB3
0.7536
EMD
0.7196
DAG1
0.6937
TCF7
0.5551
CTNNB1
0.5466
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
646048
646821
hsa05020
(boxplot)
33363.30513597390729744.746516631067843E-40.007037817549161440.08333333333333333FYN
3.7055
MAP2K2
3.3627
C1QA
3.1690
C1QB
C1QC
BAX
3.0299
C8A
2.9901
PRKACB
2.9293
PRNP
2.8953
PRKX
2.6609
STIP1
2.5557
C7
2.5419
NCAM2
2.4471
C6
2.3864
HSPA1A
2.1511
MAPK1
1.9571
LAMC1
1.9271
IL1B
1.8813
NCAM1
1.8672
MAPK3
1.8628
CCL5
1.8122
PRKACG
1.7616
IL6
1.7153
ELK1
1.6910
NOTCH1
1.6712
MAP2K1
1.5376
IL1A
1.4740
C9
1.4511
C8B
1.1957
C8G
0.8881
SOD1
0.8543
C5
0.7977
PRKACA
0.6979
HSPA5
0.6930
EGR1
0.5440
Prion diseases
hsa05223
(boxplot)
54553.28961536623900575.016221003253385E-40.007037817549161440.07692307692307693RXRB
4.6854
GRB2
3.5564
MAP2K2
3.3627
ERBB2
3.2295
FHIT
3.1100
CDKN2A
3.0353
PRKCB
2.9939
EGFR
2.8090
RXRG
2.6680
HRAS
2.6539
PIK3CD
2.5941
PIK3CG
2.5697
PLCG2
2.4205
EGF
2.1937
PRKCA
2.1719
AKT1
2.1144
FOXO3
2.0675
CDK6
2.0335
PIK3R3
2.0057
CCND1
1.9690
BRAF
1.9582
MAPK1
1.9571
PRKCG
1.9540
MAPK3
1.8628
PIK3R1
1.8351
PIK3R5
1.7900
AKT2
1.7769
RXRA
1.7596
RAF1
1.7090
BAD
1.6791
TGFA
1.6583
STK4
1.6533
CASP9
1.5727
MAP2K1
1.5376
SOS2
1.5227
AKT3
1.4293
PDPK1
1.4292
ARAF
1.3834
TP53
1.3523
PIK3CA
1.3325
E2F3
1.3139
CDK4
1.2985
PIK3R2
1.2583
RARB
1.1952
RB1
1.1822
PLCG1
1.1759
SOS1
1.1496
KRAS
0.9975
E2F2
0.9709
NRAS
0.9279
PIK3CB
0.9249
RASSF5
0.9023
E2F1
0.6669
RASSF1
0.2244
Non-small cell lung cancer
hsa04662
(boxplot)
74763.08538444009716750.00101644601915462650.0128749829092919350.07142857142857142BTK
4.4391
GRB2
3.5564
MAP2K2
3.3627
INPP5D
3.1650
PPP3R2
3.1467
CARD11
3.1018
PRKCB
2.9939
NFATC2
2.9629
CD19
2.7102
HRAS
2.6539
PIK3CD
2.5941
PIK3CG
2.5697
PLCG2
2.4205
PPP3CB
2.4174
NFKBIA
2.3376
NFATC4
2.2770
IKBKG
2.2420
BLNK
2.2008
NFATC1
2.1519
PIK3AP1
2.1387
NFKBIB
2.1358
SYK
2.1149
AKT1
2.1144
IFITM1
2.0149
PIK3R3
2.0057
VAV2
1.9727
MAPK1
1.9571
PPP3CC
1.9488
PPP3R1
1.9487
RAC1
1.9125
NFATC3
1.9050
JUN
1.8868
MAPK3
1.8628
VAV3
1.8406
PIK3R1
1.8351
CD22
1.8156
DAPP1
1.7926
PIK3R5
1.7900
AKT2
1.7769
RAF1
1.7090
RELA
1.6587
LYN
1.5986
FCGR2B
1.5909
MAP2K1
1.5376
SOS2
1.5227
FOS
1.5019
NFKB1
1.4613
CHP2
1.4539
AKT3
1.4293
PPP3CA
1.4235
VAV1
1.3902
MALT1
1.3374
PIK3CA
1.3325
RASGRP3
1.3202
LILRB3
1.3191
PIK3R2
1.2583
CR2
1.2526
GSK3B
1.1968
CHUK
1.1789
NFKBIE
1.1735
PTPN6
1.1681
SOS1
1.1496
RAC2
1.0961
CD81
1.0918
KRAS
0.9975
NRAS
0.9279
PIK3CB
0.9249
CD79A
0.8908
RAC3
0.8880
BCL10
0.8189
CD79B
0.8170
IKBKB
0.7521
NFAT5
0.7008
CD72
0.5378
B cell receptor signaling pathway
CHP
hsa04912
(boxplot)
1001023.06693452638317240.0010813311105757340.0128749829092919350.06666666666666667MAP2K6
3.6149
GRB2
3.5564
MAP2K2
3.3627
MAPK9
3.1472
MAP2K7
3.0946
PRKCB
2.9939
PLA2G4E
2.9874
PLCB3
2.9532
PRKACB
2.9293
CACNA1C
2.8754
EGFR
2.8090
PRKX
2.6609
HRAS
2.6539
PLCB1
2.6151
ADCY5
2.5811
CAMK2D
2.5615
ADCY2
2.5386
JMJD7-PLA2G4B
2.4987
PLA2G4B
PLA2G5
2.3447
PLA2G12B
2.3313
PLA2G4A
2.3298
PLD2
2.2800
CAMK2B
2.2519
PLA2G2E
2.2318
CAMK2G
2.1818
PRKCA
2.1719
ADCY3
2.1650
MAPK8
2.1614
ITPR2
2.1594
CAMK2A
2.1496
CACNA1D
2.1182
LHB
2.0612
MAPK10
2.0583
MAP3K1
1.9924
MMP14
1.9618
MAPK1
1.9571
GNRH2
1.9195
JUN
1.8868
PLCB2
1.8631
MAPK3
1.8628
MAPK7
1.8453
MAP2K4
1.8266
CALML5
1.7832
PLA2G10
1.7764
ITPR3
1.7657
PLD1
1.7651
CALML3
1.7646
PLA2G3
1.7635
PRKACG
1.7616
GNAQ
1.7558
PLA2G2A
1.7465
ADCY9
1.7405
ADCY1
1.7392
ADCY8
1.7139
RAF1
1.7090
ELK1
1.6910
MAP3K4
1.6850
MMP2
1.6530
CALML6
1.6066
MAP3K2
1.6004
SRC
1.5906
MAP2K1
1.5376
SOS2
1.5227
GNRHR
1.4994
PLA2G2F
1.4746
ADCY4
1.4548
HBEGF
1.4417
ITPR1
1.4342
ADCY7
1.4224
PLA2G6
1.3992
CACNA1S
1.3954
CALM1
1.3829
PLCB4
1.3630
GNA11
1.3379
FSHB
1.2331
PLA2G2D
1.2175
GNAS
1.1857
SOS1
1.1496
CGA
1.1299
PTK2B
1.1280
CALM2
1.1102
PLA2G12A
1.1051
CDC42
1.0907
PRKCD
1.0164
KRAS
0.9975
MAPK14
0.9700
CACNA1F
0.9583
ATF4
0.9491
MAP3K3
0.9421
NRAS
0.9279
MAPK11
0.8399
MAPK12
0.8399
CALM3
0.8371
PLA2G2C
0.7622
ADCY6
0.7536
PRKACA
0.6979
GNRH1
0.6442
MAPK13
0.6142
MAP2K3
0.5826
PLA2G1B
0.4953
GnRH signaling pathway
hsa05414
(boxplot)
89933.00182562646427350.00134182925240655670.0149969151739556320.0625DMD
3.6492
RYR2
3.1737
CACNB4
3.1376
TNF
3.0639
SGCG
3.0172
PRKACB
2.9293
CACNA1C
2.8754
SLC8A1
2.7718
ITGA2
2.6856
CACNG3
2.6709
PRKX
2.6609
ADCY5
2.5811
ITGA1
2.5638
ADCY2
2.5386
ITGA9
2.5201
TPM3
2.4781
TTN
2.4386
SGCD
2.3072
CACNG4
2.2546
LAMA2
2.2226
CACNB2
2.2123
ITGB3
2.1729
ADCY3
2.1650
ACTB
2.1337
CACNA1D
2.1182
ITGB5
2.0784
TNNI3
2.0145
ITGA10
2.0120
CACNA2D1
1.9982
CACNA2D3
1.9648
CACNG7
1.9540
ITGA8
1.9537
MYBPC3
1.9461
ITGB6
1.9218
ACTG1
1.9056
SGCB
1.8841
MYL3
1.8709
TNNC1
1.8440
CACNG1
1.8336
MYH6
1.8142
MYH7
1.8142
SGCA
1.7693
PRKACG
1.7616
ITGAV
1.7509
ADCY9
1.7405
ADCY1
1.7392
ITGA11
1.7210
ADCY8
1.7139
CACNA2D2
1.6959
CACNG6
1.6930
ATP2A2
1.6834
ITGA4
1.6794
CACNG5
1.6745
ADRB1
1.6047
IGF1
1.6014
TPM1
1.5971
TGFB2
1.5799
MYL2
1.5502
ITGA2B
1.5355
ADCY4
1.4548
ADCY7
1.4224
CACNA2D4
1.4192
CACNA1S
1.3954
CACNG2
1.3692
DES
1.3358
ITGA3
1.3270
TPM4
1.3177
CACNG8
1.2699
TNNT2
1.2243
TPM2
1.1946
GNAS
1.1857
ITGB7
1.1840
CACNB1
1.1775
ITGA7
1.1296
ITGB1
1.1192
ACTC1
1.1031
LMNA
1.0722
TGFB3
1.0107
TGFB1
0.9693
CACNA1F
0.9583
PLN
0.9193
ITGB4
0.8918
ITGB8
0.8819
ITGA6
0.8763
ITGA5
0.8380
ADCY6
0.7536
CACNB3
EMD
0.7196
PRKACA
0.6979
DAG1
0.6937
Dilated cardiomyopathy
646048
646821
hsa04320
(boxplot)
24262.96000929004353350.00153814882812475240.0162360154079834970.058823529411764705ETS2
4.1147
GRB2
3.5564
ETV7
2.8166
EGFR
2.8090
PIWIL1
2.7664
SPIRE1
2.3505
SPIRE2
2.2180
CPEB1
2.2018
ETV6
2.0609
PIWIL4
2.0278
MAPK1
1.9571
PIWIL2
1.9058
MAPK3
1.8628
NOTCH1
1.6712
FMN2
1.6318
NOTCH4
1.5913
MAP2K1
1.5376
SOS2
1.5227
NOTCH2
1.3830
NOTCH3
1.2976
ETS1
1.2531
PIWIL3
1.1632
SOS1
1.1496
KRAS
0.9975
Dorso-ventral axis formation
LOC652554
hsa04512
(boxplot)
84852.91367697744976440.00178599652101973930.0178599652101973930.05555555555555555COL11A2
4.6854
TNN
4.2700
TNR
3.0413
LAMA3
2.9086
COL4A2
2.8351
COL6A2
2.7393
ITGA2
2.6856
COL4A1
2.5872
ITGA1
2.5638
ITGA9
2.5201
THBS2
2.4552
SV2C
2.4442
CD44
2.4166
LAMA5
2.3426
GP1BB
2.2712
RELN
2.2249
LAMA2
2.2226
SV2A
2.1873
ITGB3
2.1729
SPP1
2.1654
TNXB
2.1180
COL6A1
2.1167
ITGB5
2.0784
LAMB1
2.0735
LAMA4
2.0531
LAMB3
2.0178
ITGA10
2.0120
ITGA8
1.9537
FN1
1.9294
LAMC1
1.9271
ITGB6
1.9218
TNC
1.9083
COL5A1
1.9082
COL6A3
1.8501
VTN
1.8442
LAMC2
1.8307
THBS3
1.8194
ITGAV
1.7509
THBS4
1.7325
LAMA1
1.7275
ITGA11
1.7210
COL6A6
1.6842
ITGA4
1.6794
COL4A4
1.6590
LAMB4
1.6528
SDC2
1.6349
SV2B
1.6279
GP9
1.6135
HMMR
1.6027
GP6
1.5666
ITGA2B
1.5355
IBSP
1.5119
AGRN
1.5051
LAMB2
1.4979
COL1A1
1.4835
COL3A1
1.4690
SDC3
1.4674
CD36
1.4667
COL5A2
1.4504
COL11A1
1.4339
COL1A2
1.4123
VWF
1.4032
COL5A3
1.3492
COL4A6
1.3398
ITGA3
1.3270
COL2A1
1.3191
HSPG2
1.2964
SDC4
1.2900
CHAD
1.2469
GP5
1.2192
ITGB7
1.1840
LAMC3
1.1743
ITGA7
1.1296
ITGB1
1.1192
SDC1
1.0557
COMP
1.0103
GP1BA
0.9659
ITGB4
0.8918
ITGB8
0.8819
ITGA6
0.8763
CD47
0.8677
ITGA5
0.8380
THBS1
0.7292
DAG1
0.6937
ECM-receptor interaction
hsa04514
(boxplot)
1271372.9062856573887760.00182873691459040090.0178599652101973930.05263157894736842HLA-DMA
4.6143
HLA-DOA
4.4996
CDH2
3.9744
VCAN
3.6291
NRXN1
3.6097
CNTNAP2
3.1556
CLDN23
3.1016
CDH4
3.0350
NFASC
2.9513
NLGN1
2.7866
PTPRM
2.7283
MPZ
2.7198
JAM3
2.6353
HLA-DMB
2.6120
CD6
2.5826
PTPRF
2.5339
MPZL1
2.5263
ITGA9
2.5201
ITGB2
2.5057
CD40
2.4680
NCAM2
2.4471
SIGLEC1
2.3633
HLA-DQA1
2.3613
CD8B
2.3235
CLDN6
2.3109
CLDN9
NLGN4X
2.3043
HLA-F
2.2828
CNTN2
2.2820
CADM1
2.2215
PDCD1LG2
2.1876
CD28
2.1569
HLA-DRB1
2.1516
CD276
2.1515
PECAM1
2.1136
CLDN1
2.0629
CD4
2.0421
CD8A
CLDN15
2.0275
CD274
2.0243
CLDN18
2.0192
SELL
1.9952
CD80
1.9711
ITGA8
1.9537
CD86
1.9313
NRXN3
1.8833
MAG
1.8819
NCAM1
1.8672
CD2
1.8423
HLA-DRB5
1.8305
CD22
1.8156
ITGAV
1.7509
CADM3
1.7482
HLA-DQB1
1.7437
NEGR1
1.7375
PVR
1.7307
CNTN1
1.7178
JAM2
1.7173
PVRL2
1.7152
VCAM1
1.7110
ITGA4
1.6794
ICAM1
1.6718
CDH5
1.6622
HLA-B
1.6543
SDC2
1.6349
ALCAM
1.6069
NLGN3
1.5936
HLA-DOB
1.5897
CLDN14
1.5897
OCLN
1.5772
CD58
1.5695
SELP
1.5609
NEO1
1.5579
PVRL1
1.5566
NRCAM
1.5362
PDCD1
1.5356
HLA-DQA2
1.5353
HLA-G
1.5161
HLA-DPA1
1.4883
HLA-DPB1
SDC3
1.4674
CLDN5
1.4433
HLA-A
PTPRC
1.4182
CLDN20
1.3757
CLDN22
1.3696
ITGAL
1.3652
MADCAM1
1.3312
ICAM3
1.3158
SDC4
1.2900
HLA-DRA
1.2787
HLA-E
1.2721
CNTNAP1
1.2662
ESAM
1.2599
CLDN3
1.2507
HLA-DRB3
1.2503
SELPLG
1.2439
SPN
1.2252
ICOS
1.2215
CDH1
1.2150
ICOSLG
1.2062
ITGB7
1.1840
SELE
1.1773
CLDN8
1.1715
CLDN17
1.1407
CLDN7
1.1371
HLA-C
1.1295
CD226
1.1277
ITGB1
1.1192
CLDN4
1.1151
CLDN19
1.0776
CDH15
1.0574
SDC1
1.0557
CTLA4
1.0433
NRXN2
0.9962
GLG1
0.9814
CDH3
0.9414
ICAM2
0.9308
CD34
0.9161
PVRL3
0.9077
CLDN2
0.8826
ITGB8
0.8819
ITGA6
0.8763
CLDN10
0.7506
ITGAM
0.7270
CLDN16
0.6937
NLGN2
0.6604
CLDN11
0.6198
F11R
0.6028
L1CAM
0.6002
CD40LG
0.3570
Cell adhesion molecules (CAMs)
100294318
CD99
HLA-DRB4
LOC100133583
LOC652614
hsa04940
(boxplot)
39472.90424409596314970.00184070508854305980.0178599652101973930.05HLA-DMA
4.6143
HLA-DOA
4.4996
ICA1
3.4698
FAS
3.2882
LTA
3.0639
TNF
PTPRN2
2.8388
HLA-DMB
2.6120
HLA-DQA1
2.3613
HLA-F
2.2828
CD28
2.1569
HLA-DRB1
2.1516
INS
1.9742
CD80
1.9711
CD86
1.9313
IL1B
1.8813
HLA-DRB5
1.8305
FASLG
1.8023
IL12A
1.7919
PTPRN
1.7755
HLA-DQB1
1.7437
HLA-B
1.6543
HSPD1
1.5925
HLA-DOB
1.5897
HLA-DQA2
1.5353
HLA-G
1.5161
HLA-DPA1
1.4883
HLA-DPB1
IL1A
1.4740
HLA-A
CPE
1.4083
HLA-DRA
1.2787
HLA-E
1.2721
IL2
1.2715
HLA-DRB3
1.2503
HLA-C
1.1295
GAD1
1.0859
GZMB
0.9911
IFNG
0.8931
GAD2
0.8924
IL12B
0.7568
PRF1
0.7335
Type I diabetes mellitus
100294318
HLA-DRB4
LOC100133583
LOC652614
hsa04520
(boxplot)
73762.9032550610432480.00184652864180578910.0178599652101973930.047619047619047616FYN
3.7055
ERBB2
3.2295
INSR
3.1624
CTNNA3
3.1603
MAP3K7
3.1402
ACTN3
3.1352
EGFR
2.8090
BAIAP2
2.7979
PTPRM
2.7283
CSNK2A1
2.7243
SNAI2
2.6919
PTPRF
2.5339
YES1
2.4165
IGF1R
2.4090
CTNNA2
2.3669
CSNK2A2
2.3563
TCF7L1
2.3158
FARP2
2.2728
WASF1
2.1938
CSNK2B
2.1620
SMAD3
2.1433
ACTB
2.1337
TCF7L2
2.0892
PTPRB
2.0671
PARD3
2.0430
ACTN1
2.0386
MAPK1
1.9571
RAC1
1.9125
ACTG1
1.9056
FER
1.8987
RHOA
1.8947
MAPK3
1.8628
LEF1
1.7470
WASF3
1.7392
ACTN2
1.7215
PVRL2
1.7152
CREBBP
1.7131
VCL
1.7125
SORBS1
1.6523
SMAD4
1.6061
TGFBR2
1.5967
SRC
1.5906
FGFR1
1.5730
PTPRJ
1.5709
PVRL1
1.5566
LMO7
1.5430
EP300
1.4888
ACTN4
1.4437
NLK
1.4362
PTPN1
1.4205
ACP1
1.4136
SNAI1
1.3990
CTNNA1
1.3657
IQGAP1
1.2792
TJP1
1.2276
CDH1
1.2150
PTPN6
1.1681
WASL
1.1528
MET
1.1441
TGFBR1
1.1193
WAS
1.1123
RAC2
1.0961
CDC42
1.0907
CTNND1
1.0729
MLLT4
1.0402
SMAD2
1.0065
WASF2
0.9881
PVRL4
0.9395
PVRL3
0.9077
RAC3
0.8880
SSX2IP
0.8623
TCF7
0.5551
CTNNB1
0.5466
Adherens junction
646048
646821
hsa04666
(boxplot)
93962.9030770131002220.0018475787863478920.0178599652101973930.045454545454545456CRK
4.9972
AMPH
3.4482
DNM3
3.4277
INPP5D
3.1650
DNM2
3.0383
PRKCB
2.9939
PLA2G4E
2.9874
ARPC4
2.9695
LAT
2.8728
PRKCE
2.7354
CFL2
2.6485
PIK3CD
2.5941
PIK3CG
2.5697
PLA2G4B
2.4987
PLCG2
2.4205
PLA2G4A
2.3298
CRKL
2.3083
PLD2
2.2800
GAB2
2.2298
DOCK2
2.2237
WASF1
2.1938
PRKCA
2.1719
SYK
2.1149
AKT1
2.1144
PLA2G4D
2.0990
PIP5K1A
2.0835
PLA2G4F
2.0368
DNM1
2.0164
PIK3R3
2.0057
VAV2
1.9727
MAPK1
1.9571
PRKCG
1.9540
ASAP1
1.9430
RPS6KB2
1.9131
RAC1
1.9125
SPHK2
1.8974
MAPK3
1.8628
VAV3
1.8406
PIK3R1
1.8351
PIK3R5
1.7900
MYO10
1.7867
AKT2
1.7769
PIP5K1B
1.7709
PLD1
1.7651
WASF3
1.7392
PIP5K1C
1.7353
RAF1
1.7090
ARPC1A
1.7079
ARPC1B
ASAP2
1.6780
SCIN
1.6737
MARCKS
1.6411
LYN
1.5986
FCGR2B
1.5909
MAP2K1
1.5376
LIMK2
1.5338
SPHK1
1.5010
HCK
1.4790
PPAP2B
1.4601
AKT3
1.4293
PTPRC
1.4182
PLA2G6
1.3992
VAV1
1.3902
VASP
1.3560
PIK3CA
1.3325
FCGR2A
1.2669
CFL1
1.2636
PIK3R2
1.2583
RPS6KB1
1.2260
ARPC5L
1.2241
FCGR3A
1.2047
FCGR2C
1.2003
LIMK1
1.1825
PLCG1
1.1759
DNM1L
1.1573
ARF6
1.1563
WASL
1.1528
PAK1
1.1424
WAS
1.1123
RAC2
1.0961
CDC42
1.0907
ARPC3
1.0531
GSN
1.0374
PPAP2A
1.0217
NCF1
1.0210
PRKCD
1.0164
WASF2
0.9881
PPAP2C
0.9653
FCGR1A
0.9281
PIK3CB
0.9249
ASAP3
0.8369
MARCKSL1
0.8048
ARPC5
0.7879
ARPC2
0.4034
Fc gamma R-mediated phagocytosis
LOC653888
hsa04930
(boxplot)
47482.8789188167438850.00199520520767326740.0178599652101973930.043478260869565216INSR
3.1624
MAPK9
3.1472
TNF
3.0639
CACNA1G
3.0242
CACNA1C
2.8754
PRKCE
2.7354
PIK3CD
2.5941
PIK3CG
2.5697
MAFA
2.5049
PKM2
2.3177
GCK
2.2586
MAPK8
2.1614
HK1
2.1198
CACNA1D
2.1182
CACNA1E
2.0970
MAPK10
2.0583
PIK3R3
2.0057
SOCS4
2.0014
SOCS1
1.9877
INS
1.9742
MAPK1
1.9571
CACNA1A
1.9305
IRS1
1.9115
MAPK3
1.8628
CACNA1B
1.8481
HK2
1.8360
PIK3R1
1.8351
IRS2
1.8084
PRKCZ
1.7929
PIK3R5
1.7900
MTOR
1.7516
ABCC8
1.7488
SLC2A4
1.5730
PIK3CA
1.3325
ADIPOQ
1.3289
HK3
1.2805
PIK3R2
1.2583
KCNJ11
1.1557
SOCS3
1.1324
SLC2A2
1.0978
PDX1
1.0828
IRS4
1.0252
PRKCD
1.0164
PIK3CB
0.9249
PKLR
0.8529
SOCS2
0.8180
IKBKB
0.7521
Type II diabetes mellitus
hsa04730
(boxplot)
68712.83452319877185530.0022947062816165430.0178599652101973930.041666666666666664GNAO1
3.7443
MAP2K2
3.3627
GRID2
3.0003
PRKCB
2.9939
PLA2G4E
2.9874
PLCB3
2.9532
HRAS
2.6539
PLCB1
2.6151
GUCY1B3
2.5107
JMJD7-PLA2G4B
2.4987
PLA2G4B
PRKG1
2.4878
GUCY1A3
2.4867
IGF1R
2.4090
GRIA3
2.4068
PLA2G5
2.3447
GNA12
2.3370
PLA2G12B
2.3313
PLA2G4A
2.3298
NOS1
2.3035
PPP2R1B
2.2567
PLA2G2E
2.2318
PRKCA
2.1719
ITPR2
2.1594
GRM5
1.9765
BRAF
1.9582
MAPK1
1.9571
GUCY1A2
1.9560
PRKCG
1.9540
CACNA1A
1.9305
PLCB2
1.8631
MAPK3
1.8628
PLA2G10
1.7764
ITPR3
1.7657
PLA2G3
1.7635
GNAQ
1.7558
PLA2G2A
1.7465
RAF1
1.7090
GRM1
1.6533
GNAI1
1.6302
GNA13
1.6039
IGF1
1.6014
LYN
1.5986
RYR1
1.5561
MAP2K1
1.5376
PLA2G2F
1.4746
GNAI3
1.4435
ITPR1
1.4342
PLA2G6
1.3992
ARAF
1.3834
PLCB4
1.3630
CRHR1
1.3545
GNA11
1.3379
PRKG2
1.2488
PLA2G2D
1.2175
GNAS
1.1857
GRIA1
1.1475
PLA2G12A
1.1051
PPP2CB
1.0588
GNAZ
1.0149
KRAS
0.9975
GRIA2
0.9514
NRAS
0.9279
CRH
0.8287
PPP2R1A
0.7692
PLA2G2C
0.7622
PPP2CA
0.6512
GNAI2
0.5640
PLA2G1B
0.4953
Long-term depression
C7orf16
hsa03320
(boxplot)
67702.7971018449739430.002578163834171310.0188404280189441860.04RXRB
4.6854
ANGPTL4
3.7320
FABP1
3.5813
CYP4A22
3.4215
FABP7
3.0449
CPT1C
3.0381
APOA1
3.0248
APOC3
ACOX1
2.9855
GK2
2.8912
RXRG
2.6680
APOA5
2.5911
SCD
2.5543
SLC27A6
2.4755
EHHADH
2.4589
PCK1
2.3007
ACSL1
2.2283
SLC27A5
2.1872
HMGCS2
2.1809
AQP7
2.1271
ACSL5
2.0627
SLC27A4
1.9556
LPL
1.9485
CPT1B
1.8780
SCD5
1.8770
ACAA1
1.7773
RXRA
1.7596
PLTP
1.7340
GK
1.7138
CYP4A11
1.6857
ACSL6
1.6845
PPARG
1.6692
DBI
1.6603
SORBS1
1.6523
ACOX3
1.6354
SLC27A2
1.6261
ACSL3
1.6086
PPARD
1.5657
CPT2
1.5335
CD36
1.4667
PDPK1
1.4292
FABP3
1.4047
UCP1
1.3977
PLIN1
1.3583
SCP2
1.3496
SLC27A1
1.3359
UBC
1.3324
ADIPOQ
1.3289
NR1H3
1.3265
FABP4
1.3200
CYP7A1
1.3148
ACSL4
1.2837
ME1
1.2545
ACADL
1.2388
MMP1
1.2208
CPT1A
1.1834
PCK2
1.1504
ILK
1.1347
FADS2
1.0437
FABP6
1.0432
PPARA
1.0266
CYP8B1
1.0023
ACADM
0.9259
APOA2
0.8951
ACOX2
0.8479
CYP27A1
0.8385
OLR1
0.8149
FABP2
0.4716
PPAR signaling pathway
FABP5
hsa05146
(boxplot)
1041062.7151185417671610.0033126025620024980.0233109069177953560.038461538461538464COL11A2
4.6854
ACTN3
3.1352
GNAL
3.0690
TNF
3.0639
PRKCB
2.9939
C8A
2.9901
PLCB3
2.9532
PRKACB
2.9293
LAMA3
2.9086
COL4A2
2.8351
SERPINB6
2.7706
RAB5A
2.6894
PRKX
2.6609
PLCB1
2.6151
PIK3CD
2.5941
COL4A1
2.5872
PIK3CG
2.5697
ITGB2
2.5057
LAMA5
2.3426
CASP3
2.3272
LAMA2
2.2226
PRKCA
2.1719
SERPINB1
2.1416
GNA14
2.0910
SERPINB9
2.0797
LAMB1
2.0735
IL1R1
2.0721
LAMA4
2.0531
ACTN1
2.0386
LAMB3
2.0178
PIK3R3
2.0057
PRKCG
1.9540
FN1
1.9294
LAMC1
1.9271
COL5A1
1.9082
IL1B
1.8813
GNA15
1.8776
PLCB2
1.8631
PIK3R1
1.8351
CXCL1
1.8311
LAMC2
1.8307
HSPB1
1.8189
MUC2
1.8188
ARG2
1.7953
IL12A
1.7919
PIK3R5
1.7900
PRKACG
1.7616
GNAQ
1.7558
ADCY1
1.7392
LAMA1
1.7275
ACTN2
1.7215
IL6
1.7153
VCL
1.7125
CD14
1.6905
COL4A4
1.6590
RELA
1.6587
LAMB4
1.6528
CD1D
1.5801
TGFB2
1.5799
SERPINB2
1.5558
LAMB2
1.4979
COL1A1
1.4835
COL3A1
1.4690
NFKB1
1.4613
C9
1.4511
COL5A2
1.4504
ACTN4
1.4437
COL11A1
1.4339
COL1A2
1.4123
PTK2
1.3822
TLR2
1.3663
PLCB4
1.3630
COL5A3
1.3492
COL4A6
1.3398
GNA11
1.3379
PIK3CA
1.3325
COL2A1
1.3191
NOS2
1.3024
RAB7A
1.3020
IL8
1.2857
PIK3R2
1.2583
IL1R2
1.1993
C8B
1.1957
GNAS
1.1857
LAMC3
1.1743
RAB5B
1.1593
SERPINB3
1.1457
SERPINB4
1.1457
RAB5C
1.0789
TGFB3
1.0107
CSF2
0.9905
TLR4
0.9855
TGFB1
0.9693
PIK3CB
0.9249
IFNG
0.8931
C8G
0.8881
IL10
0.8668
IL12B
0.7568
ITGAM
0.7270
PRKACA
0.6979
ARG1
0.6535
CTSG
0.6388
SERPINB10
0.6198
SERPINB13
0.5944
Amoebiasis
RAB7B
hsa00512
(boxplot)
30312.6265969682019430.0043121707901436770.0292611589331178080.037037037037037035GALNT13
4.0956
WBSCR17
3.3043
GALNTL2
2.8218
B3GNT6
2.7492
GALNTL1
2.7475
GALNTL6
2.6522
GALNT9
2.4894
GALNT2
2.4501
GALNT8
2.4089
GALNTL4
2.3850
GALNT6
2.1597
GALNT3
2.1595
GALNT14
2.0999
GCNT4
1.8774
GCNT1
1.8670
ST3GAL1
1.8522
B4GALT5
1.7995
GALNTL5
1.6948
GALNT5
1.5463
GALNT1
1.3774
ST3GAL2
1.3486
C1GALT1
1.3390
GALNT7
1.3252
GALNT10
1.1544
GALNT4
1.1174
C1GALT1C1
1.0766
GALNT12
1.0326
GALNT11
0.8956
GCNT3
0.6915
ST6GALNAC1
0.6046
O-Glycan biosynthesis
hsa05100
(boxplot)
69742.61989438246757580.0043978501710775220.0292611589331178080.03571428571428571CRK
4.9972
CAV1
3.7656
DNM3
3.4277
CTNNA3
3.1603
ELMO1
3.0591
CTTN
3.0455
DNM2
3.0383
ARPC4
2.9695
ARHGAP10
2.9174
CAV2
2.8160
PIK3CD
2.5941
PIK3CG
2.5697
RHOG
2.4848
CAV3
2.3881
CTNNA2
2.3669
CRKL
2.3083
WASF1
2.1938
ACTB
2.1337
GAB1
2.1327
DOCK1
2.0545
DNM1
2.0164
PIK3R3
2.0057
CBL
1.9784
FN1
1.9294
RAC1
1.9125
ACTG1
1.9056
RHOA
1.8947
SHC4
1.8427
PIK3R1
1.8351
HCLS1
1.8175
CLTCL1
1.8029
PIK3R5
1.7900
CBLB
1.7575
SHC2
1.7321
VCL
1.7125
ARPC1A
1.7079
ARPC1B
BCAR1
1.6063
SRC
1.5906
CBLC
1.5609
MAD2L2
1.5156
CLTA
1.4478
SHC3
1.4335
ARHGEF26
1.4139
PTK2
1.3822
CTNNA1
1.3657
PIK3CA
1.3325
SHC1
1.2933
CLTC
1.2691
PIK3R2
1.2583
ARPC5L
1.2241
CDH1
1.2150
DNM1L
1.1573
WASL
1.1528
MET
1.1441
ILK
1.1347
ITGB1
1.1192
WAS
1.1123
CDC42
1.0907
ARPC3
1.0531
PXN
1.0115
WASF2
0.9881
CLTB
0.9372
PIK3CB
0.9249
ITGA5
0.8380
ARPC5
0.7879
CTNNB1
0.5466
SEPT1
0.4455
CD2AP
0.4312
ARPC2
0.4034
Bacterial invasion of epithelial cells
646048
646821
LOC653888
hsa05218
(boxplot)
71722.57743074383810280.0049768912897409920.0315203115016929460.034482758620689655FGF19
4.0340
PDGFD
3.4500
MAP2K2
3.3627
CDKN2A
3.0353
EGFR
2.8090
PDGFC
2.6869
HRAS
2.6539
PIK3CD
2.5941
PIK3CG
2.5697
FGF12
2.5490
FGF7
2.5131
FGF13
2.4167
IGF1R
2.4090
FGF17
2.4040
FGF11
2.2963
FGF1
2.2613
FGF23
2.2484
FGF22
2.2464
EGF
2.1937
AKT1
2.1144
CDK6
2.0335
FGF4
2.0087
PIK3R3
2.0057
CCND1
1.9690
BRAF
1.9582
MAPK1
1.9571
FGF9
1.8959
MAPK3
1.8628
FGF14
1.8434
PIK3R1
1.8351
FGF8
1.7956
PIK3R5
1.7900
AKT2
1.7769
RAF1
1.7090
FGF18
1.7053
MITF
1.6908
BAD
1.6791
PDGFRA
1.6489
IGF1
1.6014
FGF5
1.6008
FGF3
1.5781
FGFR1
1.5730
MAP2K1
1.5376
PDGFA
1.5347
CDKN1A
1.5286
AKT3
1.4293
PTEN
1.3846
ARAF
1.3834
TP53
1.3523
PIK3CA
1.3325
E2F3
1.3139
CDK4
1.2985
FGF21
1.2670
PIK3R2
1.2583
FGF20
1.2458
HGF
1.2321
PDGFRB
1.2307
CDH1
1.2150
RB1
1.1822
MET
1.1441
FGF2
1.1278
FGF16
1.0317
PDGFB
1.0240
KRAS
0.9975
FGF6
0.9927
E2F2
0.9709
NRAS
0.9279
PIK3CB
0.9249
MDM2
0.7327
FGF10
0.7055
E2F1
0.6669
Melanoma
hsa00230
(boxplot)
1601622.51610703312483560.0059329570686679210.0363632852595775840.03333333333333333POLA1
6.3131
PDE2A
3.7330
POLR2H
3.5399
ADCY10
3.5194
PDE10A
3.5081
NT5C
3.4358
ADK
3.4277
PDE4B
3.1574
FHIT
3.1100
PDE8A
3.0407
APRT
3.0059
AK5
2.9729
PDE11A
2.9328
PDE4D
2.8834
PRHOXNB
2.7949
PNP
2.7166
GUCY2D
2.6485
GUCY2C
2.6418
PPAT
2.6276
PDE7B
2.6103
ADCY5
2.5811
POLR3F
2.5747
ADCY2
2.5386
GUCY1B3
2.5107
ENTPD6
2.5066
GUCY1A3
2.4867
NT5C1B
2.3958
PDE3A
2.3821
PGM1
2.3707
AK7
2.3456
PKM2
2.3177
ITPA
2.3045
XDH
2.2615
PDE6C
2.2565
GUK1
2.2368
POLE3
2.2350
ALLC
2.2060
PDE1C
2.1963
PRUNE
2.1770
ADCY3
2.1650
PAPSS2
2.1647
POLE2
2.1436
GMPR
2.1131
ENTPD2
2.0879
PNPT1
2.0485
AMPD2
2.0473
NUDT9
1.9892
GUCY1A2
1.9560
POLR2E
1.9538
POLR3G
1.9487
POLR3B
1.9387
PGM2
1.9257
POLR3A
1.9173
NT5C1A
1.9097
POLR3K
1.8896
ZNRD1
1.8731
POLR3GL
1.8599
NT5C2
1.8235
POLR1D
1.8224
POLR3D
1.8165
IMPDH2
1.8077
ENTPD1
1.7988
PDE9A
1.7763
POLR2L
1.7743
NME3
1.7605
ADCY9
1.7405
ADCY1
1.7392
AK1
1.7279
AK4
1.7279
ADCY8
1.7139
PDE3B
1.7081
NME6
1.6957
POLD2
1.6500
POLR3C
1.6400
PAICS
1.6241
NME5
1.6035
NUDT5
1.5956
ENPP3
1.5651
NME1
1.5583
NME1-NME2
ATIC
1.5516
PDE6A
1.5259
PDE1A
1.5160
POLR1C
1.4944
PAPSS1
1.4777
NME2
1.4706
PRIM2
1.4553
ADCY4
1.4548
NME4
1.4514
DCK
1.4347
PDE4C
1.4334
ADA
1.4333
IMPDH1
1.4289
ADCY7
1.4224
PDE6H
1.3989
POLR1A
1.3815
PDE8B
1.3712
ADSSL1
1.3671
AMPD3
1.3511
POLA2
1.3369
NPR1
1.3340
POLR2B
1.3262
PRPS2
1.3147
POLD3
1.2925
ENTPD4
1.2769
ENTPD3
1.2522
PDE7A
1.2485
NUDT2
1.2442
GUCY2F
1.2384
ENPP1
1.1901
PDE1B
1.1847
NT5C3
1.1841
POLR3H
1.1726
POLD1
1.1632
PDE6B
1.1598
CANT1
1.1564
NT5M
1.1487
POLR1E
1.1465
NT5E
1.1463
C17orf48
1.1438
PDE5A
1.1185
POLR2A
1.1129
PRPS1L1
1.1035
POLD4
1.1031
POLR2G
1.0971
POLR2D
1.0905
POLE
1.0804
PDE6G
1.0776
PDE6D
1.0743
ADSL
1.0704
AK2
1.0468
GMPR2
1.0126
DGUOK
0.9941
POLR2K
0.9675
NPR2
0.9581
RRM1
0.9485
POLR2I
0.9405
AMPD1
0.9279
POLR2J
0.9216
RRM2
0.9109
PFAS
0.9081
GART
0.8769
RRM2B
0.8716
PKLR
0.8529
GMPS
0.8402
ENTPD5
0.8155
ENTPD8
0.8155
HPRT1
0.8115
ADSS
0.7750
POLR2F
0.7730
ADCY6
0.7536
PDE4A
0.7502
NME7
0.7358
PRPS1
0.6901
POLR2J2
0.6737
POLR2J3
0.6737
POLR1B
0.6651
PRIM1
0.6558
POLE4
0.6505
GDA
0.6345
POLR2C
0.4547
Purine metabolism
hsa05213
(boxplot)
52532.44603213408099450.007221906322586680.042880068790358410.03225806451612903GRB2
3.5564
MAP2K2
3.3627
ERBB2
3.2295
CTNNA3
3.1603
EGFR
2.8090
HRAS
2.6539
PIK3CD
2.5941
PIK3CG
2.5697
APC2
2.3743
CTNNA2
2.3669
TCF7L1
2.3158
EGF
2.1937
AKT1
2.1144
TCF7L2
2.0892
FOXO3
2.0675
PIK3R3
2.0057
AXIN1
1.9756
CCND1
1.9690
BRAF
1.9582
MYC
1.9575
MAPK1
1.9571
MAPK3
1.8628
PIK3R1
1.8351
PIK3R5
1.7900
AKT2
1.7769
LEF1
1.7470
RAF1
1.7090
ELK1
1.6910
BAD
1.6791
CASP9
1.5727
MAP2K1
1.5376
SOS2
1.5227
APC
1.5096
AKT3
1.4293
PDPK1
1.4292
PTEN
1.3846
ARAF
1.3834
AXIN2
1.3665
CTNNA1
1.3657
TP53
1.3523
PIK3CA
1.3325
MLH1
1.3098
PIK3R2
1.2583
CDH1
1.2150
GSK3B
1.1968
SOS1
1.1496
ILK
1.1347
KRAS
0.9975
NRAS
0.9279
PIK3CB
0.9249
TCF7
0.5551
CTNNB1
0.5466
Endometrial cancer
hsa05332
(boxplot)
37452.41349818146110050.0079001033661875160.045485443623503880.03125HLA-DMA
4.6143
HLA-DOA
4.4996
FAS
3.2882
TNF
3.0639
KLRD1
2.7479
HLA-DMB
2.6120
HLA-DQA1
2.3613
HLA-F
2.2828
CD28
2.1569
HLA-DRB1
2.1516
CD80
1.9711
KLRC1
1.9399
CD86
1.9313
IL1B
1.8813
HLA-DRB5
1.8305
FASLG
1.8023
HLA-DQB1
1.7437
IL6
1.7153
HLA-B
1.6543
HLA-DOB
1.5897
HLA-DQA2
1.5353
KIR3DL2
1.5266
HLA-G
1.5161
HLA-DPA1
1.4883
HLA-DPB1
KIR3DL1
1.4758
IL1A
1.4740
HLA-A
HLA-DRA
1.2787
HLA-E
1.2721
IL2
1.2715
HLA-DRB3
1.2503
HLA-C
1.1295
GZMB
0.9911
KIR2DL5A
0.9653
KIR2DL1
0.9172
KIR2DL3
IFNG
0.8931
PRF1
0.7335
KIR2DL2
0.6972
Graft-versus-host disease
100294318
HLA-DRB4
LOC100133583
LOC652614
hsa05410
(boxplot)
83862.4004707073191190.0081870006076486530.045750885748624830.030303030303030304PRKAG2
3.7137
DMD
3.6492
RYR2
3.1737
CACNB4
3.1376
TNF
3.0639
SGCG
3.0172
CACNA1C
2.8754
SLC8A1
2.7718
ITGA2
2.6856
CACNG3
2.6709
ITGA1
2.5638
ITGA9
2.5201
TPM3
2.4781
TTN
2.4386
SGCD
2.3072
CACNG4
2.2546
LAMA2
2.2226
CACNB2
2.2123
ITGB3
2.1729
ACTB
2.1337
CACNA1D
2.1182
ITGB5
2.0784
TNNI3
2.0145
ITGA10
2.0120
CACNA2D1
1.9982
CACNA2D3
1.9648
CACNG7
1.9540
ITGA8
1.9537
MYBPC3
1.9461
ITGB6
1.9218
ACTG1
1.9056
SGCB
1.8841
MYL3
1.8709
PRKAA2
1.8703
TNNC1
1.8440
CACNG1
1.8336
MYH6
1.8142
MYH7
1.8142
SGCA
1.7693
ITGAV
1.7509
ITGA11
1.7210
IL6
1.7153
CACNA2D2
1.6959
CACNG6
1.6930
ATP2A2
1.6834
ITGA4
1.6794
CACNG5
1.6745
IGF1
1.6014
TPM1
1.5971
TGFB2
1.5799
MYL2
1.5502
ITGA2B
1.5355
CACNA2D4
1.4192
CACNA1S
1.3954
CACNG2
1.3692
DES
1.3358
ITGA3
1.3270
TPM4
1.3177
CACNG8
1.2699
TNNT2
1.2243
TPM2
1.1946
ITGB7
1.1840
CACNB1
1.1775
ITGA7
1.1296
ITGB1
1.1192
PRKAG1
1.1069
ACTC1
1.1031
PRKAB2
1.0760
LMNA
1.0722
PRKAG3
1.0632
PRKAB1
1.0322
TGFB3
1.0107
TGFB1
0.9693
CACNA1F
0.9583
ITGB4
0.8918
ITGB8
0.8819
ITGA6
0.8763
ITGA5
0.8380
ACE
0.7753
PRKAA1
0.7726
CACNB3
0.7536
EMD
0.7196
DAG1
0.6937
Hypertrophic cardiomyopathy (HCM)
646048
646821
hsa00603
(boxplot)
14152.3874488662798330.008482881348010230.046049927317769820.029411764705882353GLA
3.9934
HEXA
3.0328
ST8SIA1
2.8007
B3GALNT1
2.7281
FUT9
2.3791
HEXB
2.3391
ST3GAL1
1.8522
FUT2
1.6736
A4GALT
1.5256
NAGA
1.3816
ST3GAL2
1.3486
FUT1
1.1603
B3GALT5
1.1305
GBGT1
0.9052
Glycosphingolipid biosynthesis - globo series

box plot of all gene sets