data type: SNP
method: ZSCORE
K: 2
cutoff: 0.05
tolerance: 0%
Genes with the 1st to the k-th largest or smallest p-values: Exclude
Take common log and negated the p-values of genes: Yes
set name | gene count | set size | z-score | p-value | corrected p-value | FDR | gene symbols | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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hsa04510 (boxplot) | 196 | 202 | 6.212758930834349 | 2.6031166111550874E-10 | 4.945921561194666E-8 | 0.0 | CRK 4.9972 | COL11A2 4.6854 | TNN 4.2700 | CAV1 3.7656 | FYN 3.7055 | GRB2 3.5564 | PDGFD 3.4500 | MYLK 3.2871 | ERBB2 3.2295 | PARVA 3.2150 | MAPK9 3.1472 | ACTN3 3.1352 | VEGFA 3.0488 | TNR 3.0413 | PRKCB 2.9939 | PAK7 2.9767 | VEGFB 2.9601 | RASGRF1 2.9288 | LAMA3 2.9086 | TLN2 2.8514 | COL4A2 2.8351 | CAV2 2.8160 | EGFR 2.8090 | COL6A2 2.7393 | PARVG 2.7255 | PDGFC 2.6869 | ITGA2 2.6856 | PARVB 2.6643 | HRAS 2.6539 | FLT1 2.6297 | PPP1CB 2.6090 | PIK3CD 2.5941 | COL4A1 2.5872 | PIK3CG 2.5697 | ITGA1 2.5638 | ZYX 2.5465 | ITGA9 2.5201 | THBS2 2.4552 | IGF1R 2.4090 | CAV3 2.3881 | LAMA5 2.3426 | CRKL 2.3083 | RAP1A 2.2806 | RELN 2.2249 | CCND3 2.2241 | LAMA2 2.2226 | EGF 2.1937 | BCL2 2.1766 | ITGB3 2.1729 | PRKCA 2.1719 | SPP1 2.1654 | CCND2 2.1625 | MAPK8 2.1614 | ACTB 2.1337 | TNXB 2.1180 | COL6A1 2.1167 | AKT1 2.1144 | MYL10 2.1111 | ROCK2 2.0790 | ITGB5 2.0784 | LAMB1 2.0735 | MAPK10 2.0583 | DOCK1 2.0545 | LAMA4 2.0531 | ACTN1 2.0386 | MYL7 2.0341 | LAMB3 2.0178 | ITGA10 2.0120 | PIK3R3 2.0057 | VAV2 1.9727 | CCND1 1.9690 | PAK4 1.9647 | BRAF 1.9582 | MAPK1 1.9571 | PPP1R12A 1.9556 | PRKCG 1.9540 | ITGA8 1.9537 | FN1 1.9294 | LAMC1 1.9271 | ITGB6 1.9218 | RAC1 1.9125 | TNC 1.9083 | COL5A1 1.9082 | ACTG1 1.9056 | RHOA 1.8947 | JUN 1.8868 | RAPGEF1 1.8760 | MAPK3 1.8628 | COL6A3 1.8501 | VTN 1.8442 | SHC4 1.8427 | VAV3 1.8406 | PIK3R1 1.8351 | LAMC2 1.8307 | THBS3 1.8194 | ARHGAP5 1.8010 | RAP1B 1.7908 | PAK6 1.7907 | PIK3R5 1.7900 | AKT2 1.7769 | ITGAV 1.7509 | PIP5K1C 1.7353 | THBS4 1.7325 | SHC2 1.7321 | LAMA1 1.7275 | MYLK3 1.7219 | ACTN2 1.7215 | ITGA11 1.7210 | VCL 1.7125 | RAF1 1.7090 | PAK2 1.7086 | MYL9 1.7057 | ELK1 1.6910 | COL6A6 1.6842 | ITGA4 1.6794 | BAD 1.6791 | COL4A4 1.6590 | LAMB4 1.6528 | PDGFRA 1.6489 | BCAR1 1.6063 | IGF1 1.6014 | SRC 1.5906 | MYL12A 1.5886 | MYL12B | FLNC 1.5869 | VEGFC 1.5569 | KDR 1.5543 | FLNB 1.5528 | MYL2 1.5502 | MAP2K1 1.5376 | ITGA2B 1.5355 | PDGFA 1.5347 | SOS2 1.5227 | IBSP 1.5119 | LAMB2 1.4979 | COL1A1 1.4835 | COL3A1 1.4690 | COL5A2 1.4504 | ACTN4 1.4437 | COL11A1 1.4339 | SHC3 1.4335 | AKT3 1.4293 | PDPK1 1.4292 | COL1A2 1.4123 | VWF 1.4032 | CAPN2 1.3921 | BIRC2 1.3909 | BIRC3 | VAV1 1.3902 | PTEN 1.3846 | PTK2 1.3822 | DIAPH1 1.3602 | VASP 1.3560 | COL5A3 1.3492 | COL4A6 1.3398 | PIK3CA 1.3325 | ITGA3 1.3270 | COL2A1 1.3191 | PPP1CA 1.3052 | SHC1 1.2933 | FLT4 1.2760 | PIK3R2 1.2583 | CHAD 1.2469 | HGF 1.2321 | PDGFRB 1.2307 | GSK3B 1.1968 | ITGB7 1.1840 | LAMC3 1.1743 | ROCK1 1.1687 | SOS1 1.1496 | MET 1.1441 | PAK1 1.1424 | ILK 1.1347 | ITGA7 1.1296 | ITGB1 1.1192 | FIGF 1.1079 | MYLK2 1.0997 | RAC2 1.0961 | CDC42 1.0907 | PDGFB 1.0240 | PPP1CC 1.0164 | PXN 1.0115 | COMP 1.0103 | TLN1 0.9695 | FLNA 0.9266 | PIK3CB 0.9249 | ITGB4 0.8918 | RAC3 0.8880 | ITGB8 0.8819 | PAK3 0.8800 | ITGA6 0.8763 | ITGA5 0.8380 | PGF 0.7441 | THBS1 0.7292 | XIAP 0.7016 | MYL5 0.6911 | CTNNB1 0.5466 | MYLPF 0.4455 | Focal adhesion | 646048 | 646821 | GRLF1 |
hsa04012 (boxplot) | 87 | 88 | 4.413800797123702 | 5.078571293726242E-6 | 4.8246427290399296E-4 | 0.0 | CRK 4.9972 | GRB2 3.5564 | MAP2K2 3.3627 | ERBB4 3.2809 | ERBB2 3.2295 | MAPK9 3.1472 | MAP2K7 3.0946 | PRKCB 2.9939 | PAK7 2.9767 | EGFR 2.8090 | HRAS 2.6539 | PIK3CD 2.5941 | PIK3CG 2.5697 | CAMK2D 2.5615 | NRG3 2.5461 | PLCG2 2.4205 | CRKL 2.3083 | CAMK2B 2.2519 | EGF 2.1937 | NRG1 2.1819 | CAMK2G 2.1818 | PRKCA 2.1719 | MAPK8 2.1614 | NRG2 2.1614 | CAMK2A 2.1496 | GAB1 2.1327 | AKT1 2.1144 | MAPK10 2.0583 | PIK3R3 2.0057 | CBL 1.9784 | PAK4 1.9647 | BRAF 1.9582 | MYC 1.9575 | MAPK1 1.9571 | PRKCG 1.9540 | BTC 1.9365 | RPS6KB2 1.9131 | JUN 1.8868 | AREG 1.8790 | MAPK3 1.8628 | SHC4 1.8427 | PIK3R1 1.8351 | MAP2K4 1.8266 | PAK6 1.7907 | PIK3R5 1.7900 | NRG4 1.7795 | AKT2 1.7769 | CBLB 1.7575 | ABL2 1.7537 | MTOR 1.7516 | SHC2 1.7321 | RAF1 1.7090 | PAK2 1.7086 | ELK1 1.6910 | BAD 1.6791 | TGFA 1.6583 | EIF4EBP1 1.6002 | SRC 1.5906 | CBLC 1.5609 | MAP2K1 1.5376 | CDKN1A 1.5286 | SOS2 1.5227 | STAT5A 1.5114 | NCK2 1.4470 | HBEGF 1.4417 | ABL1 1.4403 | SHC3 1.4335 | AKT3 1.4293 | ARAF 1.3834 | PTK2 1.3822 | PIK3CA 1.3325 | SHC1 1.2933 | PIK3R2 1.2583 | RPS6KB1 1.2260 | GSK3B 1.1968 | PLCG1 1.1759 | CDKN1B 1.1519 | SOS1 1.1496 | PAK1 1.1424 | ERBB3 1.0409 | STAT5B 1.0063 | KRAS 0.9975 | NRAS 0.9279 | PIK3CB 0.9249 | PAK3 0.8800 | EREG 0.8038 | NCK1 0.7460 | ErbB signaling pathway | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04270 (boxplot) | 115 | 117 | 4.2094935815842796 | 1.2797185636959085E-5 | 8.104884236740755E-4 | 0.0 | CYP4A22 3.4215 | MAP2K2 3.3627 | KCNMA1 3.3055 | MYLK 3.2871 | ACTA2 3.1316 | PRKCB 2.9939 | PLA2G4E 2.9874 | PLCB3 2.9532 | PRKACB 2.9293 | CACNA1C 2.8754 | PRKCE 2.7354 | ADRA1D 2.6991 | PRKX 2.6609 | KCNMB2 2.6357 | PLCB1 2.6151 | PPP1CB 2.6090 | ADCY5 2.5811 | ADCY2 2.5386 | GUCY1B3 2.5107 | JMJD7-PLA2G4B 2.4987 | PLA2G4B | PRKG1 2.4878 | GUCY1A3 2.4867 | PPP1R14A 2.4493 | KCNMB3 2.4149 | MRVI1 2.3945 | PLA2G5 2.3447 | GNA12 2.3370 | PLA2G12B 2.3313 | PLA2G4A 2.3298 | ADORA2B 2.3294 | MYH11 2.2753 | CALD1 2.2528 | PLA2G2E 2.2318 | PRKCH 2.1900 | PRKCA 2.1719 | ADCY3 2.1650 | ADRA1A 2.1619 | ITPR2 2.1594 | CACNA1D 2.1182 | AVPR1B 2.0938 | ROCK2 2.0790 | ARHGEF11 2.0462 | RAMP3 1.9727 | BRAF 1.9582 | MAPK1 1.9571 | GUCY1A2 1.9560 | PPP1R12A 1.9556 | PRKCG 1.9540 | MYL6 1.9522 | MYL6B 1.9522 | KCNMB4 1.9400 | AGTR1 1.9300 | RHOA 1.8947 | PLCB2 1.8631 | MAPK3 1.8628 | CALCRL 1.8557 | CALML5 1.7832 | PLA2G10 1.7764 | ITPR3 1.7657 | CALML3 1.7646 | PLA2G3 1.7635 | PRKACG 1.7616 | GNAQ 1.7558 | PLA2G2A 1.7465 | ADCY9 1.7405 | ADCY1 1.7392 | MYLK3 1.7219 | ADCY8 1.7139 | RAF1 1.7090 | MYL9 1.7057 | CYP4A11 1.6857 | CALML6 1.6066 | GNA13 1.6039 | MAP2K1 1.5376 | PRKCQ 1.5129 | ADRA1B 1.4817 | PLA2G2F 1.4746 | RAMP1 1.4694 | ADCY4 1.4548 | ITPR1 1.4342 | ADCY7 1.4224 | PLA2G6 1.3992 | CACNA1S 1.3954 | ARAF 1.3834 | CALM1 1.3829 | PLCB4 1.3630 | GNA11 1.3379 | NPR1 1.3340 | PPP1CA 1.3052 | ADORA2A 1.3027 | ARHGEF12 1.2882 | PPP1R12B 1.2651 | PLA2G2D 1.2175 | GNAS 1.1857 | ROCK1 1.1687 | CALM2 1.1102 | PLA2G12A 1.1051 | MYLK2 1.0997 | KCNU1 1.0750 | KCNMB1 1.0743 | PPP1CC 1.0164 | PRKCD 1.0164 | ACTG2 1.0149 | CACNA1F 0.9583 | NPR2 0.9581 | RAMP2 0.9523 | ARHGEF1 0.8908 | CALM3 0.8371 | PTGIR 0.8371 | EDNRA 0.8058 | PLA2G2C 0.7622 | ADCY6 0.7536 | PRKACA 0.6979 | AVPR1A 0.6808 | PLA2G1B 0.4953 | Vascular smooth muscle contraction | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04360 (boxplot) | 128 | 130 | 4.103166829220369 | 2.037665817478107E-5 | 9.678912633021008E-4 | 0.0 | SEMA5A 7.2758 | DCC 5.1066 | UNC5C 4.2710 | FYN 3.7055 | SEMA4B 3.5707 | SLIT1 3.2641 | EPHA6 3.2448 | PPP3R2 3.1467 | FES 3.1088 | ROBO2 3.0085 | PAK7 2.9767 | LRRC4C 2.9758 | NFATC2 2.9629 | SLIT2 2.8500 | SEMA6A 2.7685 | PLXNB2 2.7490 | EPHA3 2.7107 | EPHB2 2.7088 | ABLIM2 2.6700 | HRAS 2.6539 | CFL2 2.6485 | EPHB1 2.6334 | UNC5D 2.5801 | CXCL12 2.5696 | EPHA1 2.5465 | SRGAP2 2.5232 | SLIT3 2.4489 | PPP3CB 2.4174 | RGS3 2.3400 | SEMA5B 2.3269 | PLXNC1 2.3225 | NFATC4 2.2770 | ABLIM1 2.2765 | SRGAP1 2.2338 | RHOD 2.2060 | EPHA5 2.1737 | UNC5B 2.1685 | ROBO1 2.1673 | NFATC1 2.1519 | ROCK2 2.0790 | SEMA3E 2.0638 | NTNG1 2.0564 | EFNA5 2.0515 | PLXNA2 2.0455 | SEMA3D 2.0149 | EFNB2 1.9944 | PAK4 1.9647 | MAPK1 1.9571 | PPP3CC 1.9488 | PPP3R1 1.9487 | RAC1 1.9125 | NFATC3 1.9050 | SEMA6C 1.9049 | RHOA 1.8947 | MAPK3 1.8628 | SEMA3G 1.8440 | PAK6 1.7907 | EPHA8 1.7658 | EFNA4 1.7569 | PAK2 1.7086 | EPHA7 1.6962 | NTN4 1.6953 | SEMA3A 1.6808 | EPHA4 1.6721 | SRGAP3 1.6565 | DPYSL2 1.6469 | GNAI1 1.6302 | NRP1 1.5851 | RASA1 1.5836 | SEMA4C 1.5761 | CDK5 1.5715 | SEMA6B 1.5688 | ROBO3 1.5671 | LIMK2 1.5338 | SEMA6D 1.4938 | CHP2 1.4539 | NCK2 1.4470 | GNAI3 1.4435 | ABL1 1.4403 | PPP3CA 1.4235 | EPHB4 1.4218 | SEMA4D 1.3860 | PTK2 1.3822 | NGEF 1.3111 | ARHGEF12 1.2882 | EFNB3 1.2849 | UNC5A 1.2805 | CFL1 1.2636 | CXCR4 1.2607 | EFNA1 1.2501 | SEMA3F 1.2271 | SEMA4F 1.2167 | PLXNA3 1.2147 | NTN1 1.2089 | GSK3B 1.1968 | PLXNB3 1.1942 | LIMK1 1.1825 | SEMA3C 1.1792 | EPHA2 1.1715 | ROCK1 1.1687 | MET 1.1441 | PAK1 1.1424 | ITGB1 1.1192 | RAC2 1.0961 | CDC42 1.0907 | EFNA3 1.0625 | KRAS 0.9975 | ABLIM3 0.9803 | EFNB1 0.9761 | EFNA2 0.9726 | NRAS 0.9279 | RAC3 0.8880 | PAK3 0.8800 | RND1 0.8600 | NTN3 0.7689 | DPYSL5 0.7538 | NCK1 0.7460 | SEMA4G 0.7362 | SEMA7A 0.7223 | NFAT5 0.7008 | SEMA4A 0.6729 | EPHB6 0.6660 | PLXNB1 0.6552 | EPHB3 0.6149 | L1CAM 0.6002 | GNAI2 0.5640 | SEMA3B 0.5640 | PLXNA1 0.4156 | Axon guidance | CHP | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04722 (boxplot) | 126 | 127 | 4.0858602005903055 | 2.1956907454545593E-5 | 9.678912633021008E-4 | 0.0 | CRK 4.9972 | NTRK3 4.8124 | YWHAE 4.5001 | GRB2 3.5564 | MAP2K2 3.3627 | NTF4 3.2839 | MAP3K5 3.1884 | MAPK9 3.1472 | MAP2K7 3.0946 | BAX 3.0299 | MAP2K5 2.8555 | NTRK2 2.7766 | RPS6KA1 2.6847 | HRAS 2.6539 | NGFRAP1 2.6339 | YWHAH 2.6079 | PIK3CD 2.5941 | PIK3CG 2.5697 | CAMK2D 2.5615 | FRS2 2.5419 | RPS6KA2 2.5126 | CAMK4 2.5094 | PLCG2 2.4205 | NFKBIA 2.3376 | ARHGDIB 2.3147 | CRKL 2.3083 | RAP1A 2.2806 | NGFR 2.2572 | CAMK2B 2.2519 | CAMK2G 2.1818 | BCL2 2.1766 | MAPK8 2.1614 | CAMK2A 2.1496 | TP73 2.1456 | NFKBIB 2.1358 | GAB1 2.1327 | AKT1 2.1144 | PTPN11 2.0897 | KIDINS220 2.0695 | FOXO3 2.0675 | MAPK10 2.0583 | NTRK1 2.0462 | NGF 2.0438 | PIK3R3 2.0057 | MAP3K1 1.9924 | IRAK3 1.9617 | BRAF 1.9582 | IRAK4 1.9582 | MAPK1 1.9571 | RAC1 1.9125 | IRS1 1.9115 | RHOA 1.8947 | JUN 1.8868 | RAPGEF1 1.8760 | MAPK3 1.8628 | MAPK7 1.8453 | SHC4 1.8427 | PIK3R1 1.8351 | IRS2 1.8084 | FASLG 1.8023 | YWHAZ 1.7916 | RAP1B 1.7908 | PIK3R5 1.7900 | CALML5 1.7832 | AKT2 1.7769 | CALML3 1.7646 | SHC2 1.7321 | RAF1 1.7090 | IRAK2 1.7090 | BAD 1.6791 | RELA 1.6587 | RPS6KA4 1.6294 | CALML6 1.6066 | RPS6KA5 1.5702 | MAP2K1 1.5376 | SOS2 1.5227 | PDK1 1.4872 | YWHAQ 1.4680 | NFKB1 1.4613 | RIPK2 1.4586 | ABL1 1.4403 | SHC3 1.4335 | AKT3 1.4293 | CALM1 1.3829 | RPS6KA3 1.3752 | SH2B2 1.3733 | TP53 1.3523 | PIK3CA 1.3325 | SHC1 1.2933 | PIK3R2 1.2583 | BDNF 1.2240 | MAGED1 1.2092 | GSK3B 1.1968 | PRDM4 1.1811 | PLCG1 1.1759 | NFKBIE 1.1735 | SOS1 1.1496 | SORT1 1.1418 | RPS6KA6 1.1135 | MAPKAPK2 1.1133 | YWHAG 1.1107 | CALM2 1.1102 | TRAF6 1.1053 | IRAK1 1.0945 | CDC42 1.0907 | CSK 1.0827 | YWHAB 1.0405 | PSEN1 1.0274 | IRS4 1.0252 | PRKCD 1.0164 | KRAS 0.9975 | ZNF274 0.9964 | NTF3 0.9832 | MAPK14 0.9700 | ATF4 0.9491 | MAP3K3 0.9421 | NRAS 0.9279 | PIK3CB 0.9249 | SH2B1 0.8855 | SH2B3 0.8791 | MAPK11 0.8399 | MAPK12 0.8399 | CALM3 0.8371 | IKBKB 0.7521 | ARHGDIA 0.6161 | MAPK13 0.6142 | Neurotrophin signaling pathway | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04720 (boxplot) | 69 | 71 | 3.7234585618687364 | 9.82560635551799E-5 | 0.003111442012580697 | 0.0 | MAP2K2 3.3627 | PPP3R2 3.1467 | PRKCB 2.9939 | PLCB3 2.9532 | PRKACB 2.9293 | CACNA1C 2.8754 | RPS6KA1 2.6847 | PRKX 2.6609 | HRAS 2.6539 | RAPGEF3 2.6418 | PLCB1 2.6151 | PPP1CB 2.6090 | CAMK2D 2.5615 | RPS6KA2 2.5126 | CAMK4 2.5094 | PPP3CB 2.4174 | GRIN2B 2.2951 | RAP1A 2.2806 | CAMK2B 2.2519 | CAMK2G 2.1818 | PRKCA 2.1719 | ITPR2 2.1594 | CAMK2A 2.1496 | GRIN2A 2.0931 | GRM5 1.9765 | GRIN2C 1.9757 | BRAF 1.9582 | MAPK1 1.9571 | PPP1R12A 1.9556 | PRKCG 1.9540 | PPP3CC 1.9488 | PPP3R1 1.9487 | PLCB2 1.8631 | MAPK3 1.8628 | RAP1B 1.7908 | CALML5 1.7832 | ITPR3 1.7657 | CALML3 1.7646 | PRKACG 1.7616 | GNAQ 1.7558 | ADCY1 1.7392 | ADCY8 1.7139 | CREBBP 1.7131 | RAF1 1.7090 | GRM1 1.6533 | CALML6 1.6066 | MAP2K1 1.5376 | EP300 1.4888 | CHP2 1.4539 | ITPR1 1.4342 | PPP1R1A 1.4284 | PPP3CA 1.4235 | ARAF 1.3834 | CALM1 1.3829 | GRIN2D 1.3766 | RPS6KA3 1.3752 | PLCB4 1.3630 | PPP1CA 1.3052 | GRIN1 1.2637 | GRIA1 1.1475 | RPS6KA6 1.1135 | CALM2 1.1102 | PPP1CC 1.0164 | KRAS 0.9975 | GRIA2 0.9514 | ATF4 0.9491 | NRAS 0.9279 | CALM3 0.8371 | PRKACA 0.6979 | Long-term potentiation | CHP | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04070 (boxplot) | 78 | 79 | 3.6598438157324926 | 1.2618451131340969E-4 | 0.00342500816422112 | 0.0 | INPP1 4.0268 | PIK3C2G 3.7146 | INPP5K 3.5378 | DGKI 3.4965 | INPP5D 3.1650 | PRKCB 2.9939 | DGKG 2.9578 | PLCB3 2.9532 | ITPKB 2.8294 | DGKZ 2.8053 | SYNJ2 2.7782 | DGKB 2.6459 | PLCB1 2.6151 | PIK3CD 2.5941 | PIK3CG 2.5697 | CDIPT 2.5282 | PI4KA 2.5044 | ITPKA 2.4578 | PLCG2 2.4205 | INPPL1 2.4159 | PRKCA 2.1719 | ITPR2 2.1594 | PIP5K1A 2.0835 | DGKH 2.0482 | PIP4K2B 2.0331 | PLCE1 2.0072 | PIK3R3 2.0057 | OCRL 2.0031 | PRKCG 1.9540 | IMPA2 1.9254 | ITPK1 1.8685 | PLCB2 1.8631 | PIK3R1 1.8351 | PIP4K2A 1.8178 | INPP5A 1.8055 | PIK3R5 1.7900 | CALML5 1.7832 | PIP5K1B 1.7709 | ITPR3 1.7657 | CALML3 1.7646 | INPP5J 1.7635 | PIP5K1C 1.7353 | PI4KB 1.7345 | CALML6 1.6066 | CDS2 1.6034 | PI4K2A 1.5996 | INPP4B 1.5917 | DGKA 1.5908 | DGKD 1.5653 | DGKQ 1.5429 | INPP4A 1.5233 | PI4K2B 1.4349 | ITPR1 1.4342 | PIK3C2B 1.3906 | PTEN 1.3846 | CALM1 1.3829 | PLCB4 1.3630 | PLCD3 1.3431 | PIK3CA 1.3325 | IPPK 1.3039 | PLCD4 1.2779 | PLCD1 1.2638 | PIK3R2 1.2583 | PLCG1 1.1759 | PIKFYVE 1.1741 | IMPA1 1.1622 | PIP4K2C 1.1372 | CALM2 1.1102 | INPP5B 1.1013 | INPP5E 1.0413 | CDS1 1.0042 | DGKE 0.9862 | PIK3CB 0.9249 | PIK3C2A 0.8669 | CALM3 0.8371 | PIK3C3 0.7608 | SYNJ1 0.6101 | PLCZ1 0.4867 | Phosphatidylinositol signaling system | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04020 (boxplot) | 175 | 179 | 3.655158854617581 | 1.2851138981950783E-4 | 0.00342500816422112 | 0.0 | MYLK 3.2871 | HTR7 3.2865 | ERBB4 3.2809 | ERBB2 3.2295 | RYR2 3.1737 | TNNC2 3.1678 | PPP3R2 3.1467 | GNAL 3.0690 | CACNA1G 3.0242 | PRKCB 2.9939 | PLCB3 2.9532 | PRKACB 2.9293 | CACNA1C 2.8754 | ATP2B2 2.8342 | ITPKB 2.8294 | HTR4 2.8101 | EGFR 2.8090 | SLC8A1 2.7718 | ADRA1D 2.6991 | PRKX 2.6609 | PLCB1 2.6151 | RYR3 2.5711 | CAMK2D 2.5615 | ADCY2 2.5386 | CAMK4 2.5094 | ITPKA 2.4578 | CACNA1H 2.4410 | PLCG2 2.4205 | PPP3CB 2.4174 | BDKRB2 2.4033 | OXTR 2.3881 | P2RX5 2.3388 | ADORA2B 2.3294 | NOS1 2.3035 | ATP2B4 2.2998 | CAMK2B 2.2519 | PDE1C 2.1963 | CAMK2G 2.1818 | PRKCA 2.1719 | ADCY3 2.1650 | ADRA1A 2.1619 | ITPR2 2.1594 | CAMK2A 2.1496 | CACNA1D 2.1182 | TACR2 2.0981 | CACNA1E 2.0970 | AVPR1B 2.0938 | GRIN2A 2.0931 | GNA14 2.0910 | CCKAR 2.0865 | PLCE1 2.0072 | GRM5 1.9765 | GRIN2C 1.9757 | PRKCG 1.9540 | P2RX1 1.9501 | PPP3CC 1.9488 | PPP3R1 1.9487 | CHRM3 1.9459 | CACNA1A 1.9305 | HTR2B 1.9303 | AGTR1 1.9300 | SLC8A3 1.9072 | SPHK2 1.8974 | GNA15 1.8776 | CYSLTR1 1.8716 | CHRM2 1.8694 | PLCB2 1.8631 | P2RX7 1.8574 | CD38 1.8553 | CACNA1B 1.8481 | TNNC1 1.8440 | VDAC3 1.8137 | EDNRB 1.7889 | HRH1 1.7853 | CALML5 1.7832 | TRHR 1.7830 | ITPR3 1.7657 | CALML3 1.7646 | PRKACG 1.7616 | LHCGR 1.7607 | GNAQ 1.7558 | ADCY9 1.7405 | ADCY1 1.7392 | TBXA2R 1.7383 | MYLK3 1.7219 | ATP2B3 1.7173 | HRH2 1.7143 | ADCY8 1.7139 | ATP2A2 1.6834 | CHRNA7 1.6719 | BST1 1.6663 | GRM1 1.6533 | PDGFRA 1.6489 | PTAFR 1.6452 | NOS3 1.6288 | CHRM5 1.6228 | CACNA1I 1.6100 | CALML6 1.6066 | ADRB1 1.6047 | HTR2A 1.5850 | RYR1 1.5561 | PTGER1 1.5412 | PDE1A 1.5160 | P2RX4 1.5095 | SPHK1 1.5010 | PHKG2 1.4975 | SLC8A2 1.4933 | HTR5A 1.4880 | ADRA1B 1.4817 | DRD1 1.4777 | ADCY4 1.4548 | CHP2 1.4539 | VDAC2 1.4467 | ITPR1 1.4342 | F2R 1.4291 | PPP3CA 1.4235 | ADCY7 1.4224 | CACNA1S 1.3954 | CALM1 1.3829 | LTB4R2 1.3819 | P2RX3 1.3783 | GRIN2D 1.3766 | PLCB4 1.3630 | ATP2A1 1.3612 | TACR1 1.3533 | CCKBR 1.3511 | HTR6 1.3475 | PTGFR 1.3436 | PLCD3 1.3431 | VDAC1 1.3400 | GNA11 1.3379 | ADRB3 1.3060 | ADORA2A 1.3027 | NOS2 1.3024 | DRD5 1.2989 | TACR3 1.2920 | PLCD4 1.2779 | PLCD1 1.2638 | GRIN1 1.2637 | PTGER3 1.2521 | PDGFRB 1.2307 | GRPR 1.2039 | GNAS 1.1857 | PDE1B 1.1847 | PLCG1 1.1759 | NTSR1 1.1495 | PPID 1.1303 | PTK2B 1.1280 | SLC25A4 1.1125 | CALM2 1.1102 | MYLK2 1.0997 | CYSLTR2 1.0547 | ADRB2 1.0467 | CHRM1 1.0409 | ERBB3 1.0409 | BDKRB1 1.0309 | PHKG1 1.0042 | ATP2A3 0.9855 | TRPC1 0.9629 | CACNA1F 0.9583 | HTR2C 0.9475 | ATP2B1 0.9361 | PLN 0.9193 | PHKA1 0.8977 | PHKA2 0.8769 | CALM3 0.8371 | SLC25A31 0.8219 | PHKB 0.8149 | EDNRA 0.8058 | P2RX6 0.7959 | SLC25A5 0.7291 | PRKACA 0.6979 | AVPR1A 0.6808 | P2RX2 0.6514 | PLCZ1 0.4867 | Calcium signaling pathway | CHP | LOC729317 | SLC25A6 | |||||||||||||||||||||||
hsa00564 (boxplot) | 78 | 80 | 3.6087413664543435 | 1.5384308316801487E-4 | 0.00342500816422112 | 0.0 | PCYT1B 7.2283 | LPGAT1 4.8079 | DGKI 3.4965 | CRLS1 3.3398 | LPCAT1 3.0227 | PLA2G4E 2.9874 | DGKG 2.9578 | DGKZ 2.8053 | CHAT 2.7603 | GPD1 2.7351 | DGKB 2.6459 | PTDSS2 2.6333 | AGPAT4 2.5633 | CDIPT 2.5282 | GPAT2 2.5064 | JMJD7-PLA2G4B 2.4987 | PLA2G4B | PLA2G5 2.3447 | PLA2G12B 2.3313 | PLA2G4A 2.3298 | PLD2 2.2800 | PLA2G2E 2.2318 | LCAT 2.1598 | LCLAT1 2.1535 | CHPT1 2.0903 | MBOAT2 2.0695 | DGKH 2.0482 | AGPAT6 2.0214 | AGPAT2 2.0126 | PLA2G15 1.9050 | CHKB 1.8780 | PCYT1A 1.8010 | ETNK1 1.7911 | PLA2G10 1.7764 | PLD1 1.7651 | PLA2G3 1.7635 | PLA2G2A 1.7465 | PISD 1.7331 | AGPAT3 1.7230 | PEMT 1.6828 | LPCAT2 1.6530 | CDS2 1.6034 | AGPAT1 1.5913 | DGKA 1.5908 | DGKD 1.5653 | DGKQ 1.5429 | MBOAT1 1.5326 | MBOAT7 1.5216 | PLA2G2F 1.4746 | PPAP2B 1.4601 | LPCAT3 1.4556 | GPAM 1.4378 | CEPT1 1.4168 | PLA2G6 1.3992 | LYPLA1 1.3969 | LPCAT4 1.3776 | EPT1 1.2808 | CHKA 1.2791 | PLA2G2D 1.2175 | PHOSPHO1 1.2170 | GNPAT 1.2058 | PTDSS1 1.1676 | C17orf48 1.1438 | ETNK2 1.1374 | GPD2 1.1148 | PGS1 1.1094 | PLA2G12A 1.1051 | TAZ 1.0762 | GPD1L 1.0398 | PPAP2A 1.0217 | CDS1 1.0042 | DGKE 0.9862 | PPAP2C 0.9653 | ACHE 0.9394 | PCYT2 0.7654 | PLA2G2C 0.7622 | LYPLA2 0.6708 | AGPAT9 0.6685 | PLA2G1B 0.4953 | Glycerophospholipid metabolism | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05416 (boxplot) | 67 | 76 | 3.4702233657411856 | 2.600128557317394E-4 | 0.004940244258903048 | 0.0 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | CAV1 3.7656 | FYN 3.7055 | DMD 3.6492 | EIF4G1 3.5399 | SGCG 3.0172 | BID 2.7152 | HLA-DMB 2.6120 | ITGB2 2.5057 | CD40 2.4680 | HLA-DQA1 2.3613 | CASP3 2.3272 | SGCD 2.3072 | HLA-F 2.2828 | MYH11 2.2753 | LAMA2 2.2226 | CXADR 2.1888 | CD28 2.1569 | HLA-DRB1 2.1516 | ACTB 2.1337 | EIF4G3 2.0618 | CD80 1.9711 | CCND1 1.9690 | CD86 1.9313 | RAC1 1.9125 | ACTG1 1.9056 | SGCB 1.8841 | HLA-DRB5 1.8305 | MYH6 1.8142 | MYH7 1.8142 | SGCA 1.7693 | ABL2 1.7537 | HLA-DQB1 1.7437 | MYH15 1.7006 | ICAM1 1.6718 | HLA-B 1.6543 | HLA-DOB 1.5897 | CASP9 1.5727 | HLA-DQA2 1.5353 | HLA-G 1.5161 | MYH1 1.5065 | MYH2 1.5065 | MYH10 1.4980 | HLA-DPA1 1.4883 | HLA-DPB1 | MYH14 1.4431 | ABL1 1.4403 | HLA-A | ITGAL 1.3652 | MYH7B 1.2798 | HLA-DRA 1.2787 | HLA-E 1.2721 | HLA-DRB3 1.2503 | CYCS 1.1994 | CASP8 1.1822 | MYH13 1.1562 | MYH4 1.1555 | MYH8 1.1555 | MYH9 1.1496 | HLA-C 1.1295 | RAC2 1.0961 | MYH3 1.0276 | CD55 0.9660 | RAC3 0.8880 | PRF1 0.7335 | DAG1 0.6937 | EIF4G2 0.5813 | CD40LG 0.3570 | Viral myocarditis | 100294318 | 646048 | 646821 | HLA-DRB4 | LOC100133583 | LOC652614 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04664 (boxplot) | 78 | 80 | 3.428132241964633 | 3.0387466786163664E-4 | 0.005248744263064633 | 0.1 | BTK 4.4391 | FYN 3.7055 | MAP2K6 3.6149 | GRB2 3.5564 | MAP2K2 3.3627 | INPP5D 3.1650 | MAPK9 3.1472 | MAP2K7 3.0946 | TNF 3.0639 | PRKCB 2.9939 | PLA2G4E 2.9874 | LAT 2.8728 | PRKCE 2.7354 | HRAS 2.6539 | PIK3CD 2.5941 | PIK3CG 2.5697 | JMJD7-PLA2G4B 2.4987 | PLA2G4B | PLCG2 2.4205 | PLA2G5 2.3447 | PLA2G12B 2.3313 | PLA2G4A 2.3298 | PLA2G2E 2.2318 | GAB2 2.2298 | PRKCA 2.1719 | MAPK8 2.1614 | SYK 2.1149 | AKT1 2.1144 | MAPK10 2.0583 | PIK3R3 2.0057 | VAV2 1.9727 | MAPK1 1.9571 | RAC1 1.9125 | MAPK3 1.8628 | VAV3 1.8406 | PIK3R1 1.8351 | MAP2K4 1.8266 | PIK3R5 1.7900 | AKT2 1.7769 | PLA2G10 1.7764 | PLA2G3 1.7635 | PLA2G2A 1.7465 | RAF1 1.7090 | IL4 1.6202 | LYN 1.5986 | MAP2K1 1.5376 | SOS2 1.5227 | PDK1 1.4872 | PLA2G2F 1.4746 | AKT3 1.4293 | MS4A2 1.4184 | PLA2G6 1.3992 | VAV1 1.3902 | PIK3CA 1.3325 | IL5 1.2733 | PIK3R2 1.2583 | PLA2G2D 1.2175 | PLCG1 1.1759 | SOS1 1.1496 | PLA2G12A 1.1051 | RAC2 1.0961 | FCER1A 1.0656 | PRKCD 1.0164 | KRAS 0.9975 | CSF2 0.9905 | IL3 0.9905 | MAPK14 0.9700 | LCP2 0.9459 | NRAS 0.9279 | PIK3CB 0.9249 | FCER1G 0.8951 | RAC3 0.8880 | MAPK11 0.8399 | MAPK12 0.8399 | IL13 0.8304 | PLA2G2C 0.7622 | MAPK13 0.6142 | MAP2K3 0.5826 | PLA2G1B 0.4953 | Fc epsilon RI signaling pathway | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05412 (boxplot) | 74 | 77 | 3.323489567110056 | 4.4449373994703834E-4 | 0.00703781754916144 | 0.09090909090909091 | CDH2 3.9744 | DMD 3.6492 | RYR2 3.1737 | CTNNA3 3.1603 | CACNB4 3.1376 | ACTN3 3.1352 | SGCG 3.0172 | CACNA1C 2.8754 | SLC8A1 2.7718 | ITGA2 2.6856 | CACNG3 2.6709 | ITGA1 2.5638 | ITGA9 2.5201 | DSG2 2.5192 | CTNNA2 2.3669 | TCF7L1 2.3158 | SGCD 2.3072 | CACNG4 2.2546 | LAMA2 2.2226 | CACNB2 2.2123 | ITGB3 2.1729 | ACTB 2.1337 | CACNA1D 2.1182 | TCF7L2 2.0892 | ITGB5 2.0784 | ACTN1 2.0386 | ITGA10 2.0120 | CACNA2D1 1.9982 | CACNA2D3 1.9648 | CACNG7 1.9540 | ITGA8 1.9537 | ITGB6 1.9218 | ACTG1 1.9056 | JUP 1.9019 | SGCB 1.8841 | CACNG1 1.8336 | SGCA 1.7693 | ITGAV 1.7509 | LEF1 1.7470 | ACTN2 1.7215 | ITGA11 1.7210 | CACNA2D2 1.6959 | CACNG6 1.6930 | ATP2A2 1.6834 | ITGA4 1.6794 | CACNG5 1.6745 | DSC2 1.6288 | ITGA2B 1.5355 | GJA1 1.5265 | ACTN4 1.4437 | CACNA2D4 1.4192 | CACNA1S 1.3954 | CACNG2 1.3692 | CTNNA1 1.3657 | DES 1.3358 | ITGA3 1.3270 | PKP2 1.2815 | CACNG8 1.2699 | ITGB7 1.1840 | CACNB1 1.1775 | ITGA7 1.1296 | ITGB1 1.1192 | LMNA 1.0722 | DSP 1.0262 | CACNA1F 0.9583 | ITGB4 0.8918 | ITGB8 0.8819 | ITGA6 0.8763 | ITGA5 0.8380 | CACNB3 0.7536 | EMD 0.7196 | DAG1 0.6937 | TCF7 0.5551 | CTNNB1 0.5466 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | 646048 | 646821 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05020 (boxplot) | 33 | 36 | 3.3051359739072974 | 4.746516631067843E-4 | 0.00703781754916144 | 0.08333333333333333 | FYN 3.7055 | MAP2K2 3.3627 | C1QA 3.1690 | C1QB | C1QC | BAX 3.0299 | C8A 2.9901 | PRKACB 2.9293 | PRNP 2.8953 | PRKX 2.6609 | STIP1 2.5557 | C7 2.5419 | NCAM2 2.4471 | C6 2.3864 | HSPA1A 2.1511 | MAPK1 1.9571 | LAMC1 1.9271 | IL1B 1.8813 | NCAM1 1.8672 | MAPK3 1.8628 | CCL5 1.8122 | PRKACG 1.7616 | IL6 1.7153 | ELK1 1.6910 | NOTCH1 1.6712 | MAP2K1 1.5376 | IL1A 1.4740 | C9 1.4511 | C8B 1.1957 | C8G 0.8881 | SOD1 0.8543 | C5 0.7977 | PRKACA 0.6979 | HSPA5 0.6930 | EGR1 0.5440 | Prion diseases | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05223 (boxplot) | 54 | 55 | 3.2896153662390057 | 5.016221003253385E-4 | 0.00703781754916144 | 0.07692307692307693 | RXRB 4.6854 | GRB2 3.5564 | MAP2K2 3.3627 | ERBB2 3.2295 | FHIT 3.1100 | CDKN2A 3.0353 | PRKCB 2.9939 | EGFR 2.8090 | RXRG 2.6680 | HRAS 2.6539 | PIK3CD 2.5941 | PIK3CG 2.5697 | PLCG2 2.4205 | EGF 2.1937 | PRKCA 2.1719 | AKT1 2.1144 | FOXO3 2.0675 | CDK6 2.0335 | PIK3R3 2.0057 | CCND1 1.9690 | BRAF 1.9582 | MAPK1 1.9571 | PRKCG 1.9540 | MAPK3 1.8628 | PIK3R1 1.8351 | PIK3R5 1.7900 | AKT2 1.7769 | RXRA 1.7596 | RAF1 1.7090 | BAD 1.6791 | TGFA 1.6583 | STK4 1.6533 | CASP9 1.5727 | MAP2K1 1.5376 | SOS2 1.5227 | AKT3 1.4293 | PDPK1 1.4292 | ARAF 1.3834 | TP53 1.3523 | PIK3CA 1.3325 | E2F3 1.3139 | CDK4 1.2985 | PIK3R2 1.2583 | RARB 1.1952 | RB1 1.1822 | PLCG1 1.1759 | SOS1 1.1496 | KRAS 0.9975 | E2F2 0.9709 | NRAS 0.9279 | PIK3CB 0.9249 | RASSF5 0.9023 | E2F1 0.6669 | RASSF1 0.2244 | Non-small cell lung cancer | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04662 (boxplot) | 74 | 76 | 3.0853844400971675 | 0.0010164460191546265 | 0.012874982909291935 | 0.07142857142857142 | BTK 4.4391 | GRB2 3.5564 | MAP2K2 3.3627 | INPP5D 3.1650 | PPP3R2 3.1467 | CARD11 3.1018 | PRKCB 2.9939 | NFATC2 2.9629 | CD19 2.7102 | HRAS 2.6539 | PIK3CD 2.5941 | PIK3CG 2.5697 | PLCG2 2.4205 | PPP3CB 2.4174 | NFKBIA 2.3376 | NFATC4 2.2770 | IKBKG 2.2420 | BLNK 2.2008 | NFATC1 2.1519 | PIK3AP1 2.1387 | NFKBIB 2.1358 | SYK 2.1149 | AKT1 2.1144 | IFITM1 2.0149 | PIK3R3 2.0057 | VAV2 1.9727 | MAPK1 1.9571 | PPP3CC 1.9488 | PPP3R1 1.9487 | RAC1 1.9125 | NFATC3 1.9050 | JUN 1.8868 | MAPK3 1.8628 | VAV3 1.8406 | PIK3R1 1.8351 | CD22 1.8156 | DAPP1 1.7926 | PIK3R5 1.7900 | AKT2 1.7769 | RAF1 1.7090 | RELA 1.6587 | LYN 1.5986 | FCGR2B 1.5909 | MAP2K1 1.5376 | SOS2 1.5227 | FOS 1.5019 | NFKB1 1.4613 | CHP2 1.4539 | AKT3 1.4293 | PPP3CA 1.4235 | VAV1 1.3902 | MALT1 1.3374 | PIK3CA 1.3325 | RASGRP3 1.3202 | LILRB3 1.3191 | PIK3R2 1.2583 | CR2 1.2526 | GSK3B 1.1968 | CHUK 1.1789 | NFKBIE 1.1735 | PTPN6 1.1681 | SOS1 1.1496 | RAC2 1.0961 | CD81 1.0918 | KRAS 0.9975 | NRAS 0.9279 | PIK3CB 0.9249 | CD79A 0.8908 | RAC3 0.8880 | BCL10 0.8189 | CD79B 0.8170 | IKBKB 0.7521 | NFAT5 0.7008 | CD72 0.5378 | B cell receptor signaling pathway | CHP | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04912 (boxplot) | 100 | 102 | 3.0669345263831724 | 0.001081331110575734 | 0.012874982909291935 | 0.06666666666666667 | MAP2K6 3.6149 | GRB2 3.5564 | MAP2K2 3.3627 | MAPK9 3.1472 | MAP2K7 3.0946 | PRKCB 2.9939 | PLA2G4E 2.9874 | PLCB3 2.9532 | PRKACB 2.9293 | CACNA1C 2.8754 | EGFR 2.8090 | PRKX 2.6609 | HRAS 2.6539 | PLCB1 2.6151 | ADCY5 2.5811 | CAMK2D 2.5615 | ADCY2 2.5386 | JMJD7-PLA2G4B 2.4987 | PLA2G4B | PLA2G5 2.3447 | PLA2G12B 2.3313 | PLA2G4A 2.3298 | PLD2 2.2800 | CAMK2B 2.2519 | PLA2G2E 2.2318 | CAMK2G 2.1818 | PRKCA 2.1719 | ADCY3 2.1650 | MAPK8 2.1614 | ITPR2 2.1594 | CAMK2A 2.1496 | CACNA1D 2.1182 | LHB 2.0612 | MAPK10 2.0583 | MAP3K1 1.9924 | MMP14 1.9618 | MAPK1 1.9571 | GNRH2 1.9195 | JUN 1.8868 | PLCB2 1.8631 | MAPK3 1.8628 | MAPK7 1.8453 | MAP2K4 1.8266 | CALML5 1.7832 | PLA2G10 1.7764 | ITPR3 1.7657 | PLD1 1.7651 | CALML3 1.7646 | PLA2G3 1.7635 | PRKACG 1.7616 | GNAQ 1.7558 | PLA2G2A 1.7465 | ADCY9 1.7405 | ADCY1 1.7392 | ADCY8 1.7139 | RAF1 1.7090 | ELK1 1.6910 | MAP3K4 1.6850 | MMP2 1.6530 | CALML6 1.6066 | MAP3K2 1.6004 | SRC 1.5906 | MAP2K1 1.5376 | SOS2 1.5227 | GNRHR 1.4994 | PLA2G2F 1.4746 | ADCY4 1.4548 | HBEGF 1.4417 | ITPR1 1.4342 | ADCY7 1.4224 | PLA2G6 1.3992 | CACNA1S 1.3954 | CALM1 1.3829 | PLCB4 1.3630 | GNA11 1.3379 | FSHB 1.2331 | PLA2G2D 1.2175 | GNAS 1.1857 | SOS1 1.1496 | CGA 1.1299 | PTK2B 1.1280 | CALM2 1.1102 | PLA2G12A 1.1051 | CDC42 1.0907 | PRKCD 1.0164 | KRAS 0.9975 | MAPK14 0.9700 | CACNA1F 0.9583 | ATF4 0.9491 | MAP3K3 0.9421 | NRAS 0.9279 | MAPK11 0.8399 | MAPK12 0.8399 | CALM3 0.8371 | PLA2G2C 0.7622 | ADCY6 0.7536 | PRKACA 0.6979 | GNRH1 0.6442 | MAPK13 0.6142 | MAP2K3 0.5826 | PLA2G1B 0.4953 | GnRH signaling pathway | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05414 (boxplot) | 89 | 93 | 3.0018256264642735 | 0.0013418292524065567 | 0.014996915173955632 | 0.0625 | DMD 3.6492 | RYR2 3.1737 | CACNB4 3.1376 | TNF 3.0639 | SGCG 3.0172 | PRKACB 2.9293 | CACNA1C 2.8754 | SLC8A1 2.7718 | ITGA2 2.6856 | CACNG3 2.6709 | PRKX 2.6609 | ADCY5 2.5811 | ITGA1 2.5638 | ADCY2 2.5386 | ITGA9 2.5201 | TPM3 2.4781 | TTN 2.4386 | SGCD 2.3072 | CACNG4 2.2546 | LAMA2 2.2226 | CACNB2 2.2123 | ITGB3 2.1729 | ADCY3 2.1650 | ACTB 2.1337 | CACNA1D 2.1182 | ITGB5 2.0784 | TNNI3 2.0145 | ITGA10 2.0120 | CACNA2D1 1.9982 | CACNA2D3 1.9648 | CACNG7 1.9540 | ITGA8 1.9537 | MYBPC3 1.9461 | ITGB6 1.9218 | ACTG1 1.9056 | SGCB 1.8841 | MYL3 1.8709 | TNNC1 1.8440 | CACNG1 1.8336 | MYH6 1.8142 | MYH7 1.8142 | SGCA 1.7693 | PRKACG 1.7616 | ITGAV 1.7509 | ADCY9 1.7405 | ADCY1 1.7392 | ITGA11 1.7210 | ADCY8 1.7139 | CACNA2D2 1.6959 | CACNG6 1.6930 | ATP2A2 1.6834 | ITGA4 1.6794 | CACNG5 1.6745 | ADRB1 1.6047 | IGF1 1.6014 | TPM1 1.5971 | TGFB2 1.5799 | MYL2 1.5502 | ITGA2B 1.5355 | ADCY4 1.4548 | ADCY7 1.4224 | CACNA2D4 1.4192 | CACNA1S 1.3954 | CACNG2 1.3692 | DES 1.3358 | ITGA3 1.3270 | TPM4 1.3177 | CACNG8 1.2699 | TNNT2 1.2243 | TPM2 1.1946 | GNAS 1.1857 | ITGB7 1.1840 | CACNB1 1.1775 | ITGA7 1.1296 | ITGB1 1.1192 | ACTC1 1.1031 | LMNA 1.0722 | TGFB3 1.0107 | TGFB1 0.9693 | CACNA1F 0.9583 | PLN 0.9193 | ITGB4 0.8918 | ITGB8 0.8819 | ITGA6 0.8763 | ITGA5 0.8380 | ADCY6 0.7536 | CACNB3 | EMD 0.7196 | PRKACA 0.6979 | DAG1 0.6937 | Dilated cardiomyopathy | 646048 | 646821 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04320 (boxplot) | 24 | 26 | 2.9600092900435335 | 0.0015381488281247524 | 0.016236015407983497 | 0.058823529411764705 | ETS2 4.1147 | GRB2 3.5564 | ETV7 2.8166 | EGFR 2.8090 | PIWIL1 2.7664 | SPIRE1 2.3505 | SPIRE2 2.2180 | CPEB1 2.2018 | ETV6 2.0609 | PIWIL4 2.0278 | MAPK1 1.9571 | PIWIL2 1.9058 | MAPK3 1.8628 | NOTCH1 1.6712 | FMN2 1.6318 | NOTCH4 1.5913 | MAP2K1 1.5376 | SOS2 1.5227 | NOTCH2 1.3830 | NOTCH3 1.2976 | ETS1 1.2531 | PIWIL3 1.1632 | SOS1 1.1496 | KRAS 0.9975 | Dorso-ventral axis formation | LOC652554 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04512 (boxplot) | 84 | 85 | 2.9136769774497644 | 0.0017859965210197393 | 0.017859965210197393 | 0.05555555555555555 | COL11A2 4.6854 | TNN 4.2700 | TNR 3.0413 | LAMA3 2.9086 | COL4A2 2.8351 | COL6A2 2.7393 | ITGA2 2.6856 | COL4A1 2.5872 | ITGA1 2.5638 | ITGA9 2.5201 | THBS2 2.4552 | SV2C 2.4442 | CD44 2.4166 | LAMA5 2.3426 | GP1BB 2.2712 | RELN 2.2249 | LAMA2 2.2226 | SV2A 2.1873 | ITGB3 2.1729 | SPP1 2.1654 | TNXB 2.1180 | COL6A1 2.1167 | ITGB5 2.0784 | LAMB1 2.0735 | LAMA4 2.0531 | LAMB3 2.0178 | ITGA10 2.0120 | ITGA8 1.9537 | FN1 1.9294 | LAMC1 1.9271 | ITGB6 1.9218 | TNC 1.9083 | COL5A1 1.9082 | COL6A3 1.8501 | VTN 1.8442 | LAMC2 1.8307 | THBS3 1.8194 | ITGAV 1.7509 | THBS4 1.7325 | LAMA1 1.7275 | ITGA11 1.7210 | COL6A6 1.6842 | ITGA4 1.6794 | COL4A4 1.6590 | LAMB4 1.6528 | SDC2 1.6349 | SV2B 1.6279 | GP9 1.6135 | HMMR 1.6027 | GP6 1.5666 | ITGA2B 1.5355 | IBSP 1.5119 | AGRN 1.5051 | LAMB2 1.4979 | COL1A1 1.4835 | COL3A1 1.4690 | SDC3 1.4674 | CD36 1.4667 | COL5A2 1.4504 | COL11A1 1.4339 | COL1A2 1.4123 | VWF 1.4032 | COL5A3 1.3492 | COL4A6 1.3398 | ITGA3 1.3270 | COL2A1 1.3191 | HSPG2 1.2964 | SDC4 1.2900 | CHAD 1.2469 | GP5 1.2192 | ITGB7 1.1840 | LAMC3 1.1743 | ITGA7 1.1296 | ITGB1 1.1192 | SDC1 1.0557 | COMP 1.0103 | GP1BA 0.9659 | ITGB4 0.8918 | ITGB8 0.8819 | ITGA6 0.8763 | CD47 0.8677 | ITGA5 0.8380 | THBS1 0.7292 | DAG1 0.6937 | ECM-receptor interaction | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04514 (boxplot) | 127 | 137 | 2.906285657388776 | 0.0018287369145904009 | 0.017859965210197393 | 0.05263157894736842 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | CDH2 3.9744 | VCAN 3.6291 | NRXN1 3.6097 | CNTNAP2 3.1556 | CLDN23 3.1016 | CDH4 3.0350 | NFASC 2.9513 | NLGN1 2.7866 | PTPRM 2.7283 | MPZ 2.7198 | JAM3 2.6353 | HLA-DMB 2.6120 | CD6 2.5826 | PTPRF 2.5339 | MPZL1 2.5263 | ITGA9 2.5201 | ITGB2 2.5057 | CD40 2.4680 | NCAM2 2.4471 | SIGLEC1 2.3633 | HLA-DQA1 2.3613 | CD8B 2.3235 | CLDN6 2.3109 | CLDN9 | NLGN4X 2.3043 | HLA-F 2.2828 | CNTN2 2.2820 | CADM1 2.2215 | PDCD1LG2 2.1876 | CD28 2.1569 | HLA-DRB1 2.1516 | CD276 2.1515 | PECAM1 2.1136 | CLDN1 2.0629 | CD4 2.0421 | CD8A | CLDN15 2.0275 | CD274 2.0243 | CLDN18 2.0192 | SELL 1.9952 | CD80 1.9711 | ITGA8 1.9537 | CD86 1.9313 | NRXN3 1.8833 | MAG 1.8819 | NCAM1 1.8672 | CD2 1.8423 | HLA-DRB5 1.8305 | CD22 1.8156 | ITGAV 1.7509 | CADM3 1.7482 | HLA-DQB1 1.7437 | NEGR1 1.7375 | PVR 1.7307 | CNTN1 1.7178 | JAM2 1.7173 | PVRL2 1.7152 | VCAM1 1.7110 | ITGA4 1.6794 | ICAM1 1.6718 | CDH5 1.6622 | HLA-B 1.6543 | SDC2 1.6349 | ALCAM 1.6069 | NLGN3 1.5936 | HLA-DOB 1.5897 | CLDN14 1.5897 | OCLN 1.5772 | CD58 1.5695 | SELP 1.5609 | NEO1 1.5579 | PVRL1 1.5566 | NRCAM 1.5362 | PDCD1 1.5356 | HLA-DQA2 1.5353 | HLA-G 1.5161 | HLA-DPA1 1.4883 | HLA-DPB1 | SDC3 1.4674 | CLDN5 1.4433 | HLA-A | PTPRC 1.4182 | CLDN20 1.3757 | CLDN22 1.3696 | ITGAL 1.3652 | MADCAM1 1.3312 | ICAM3 1.3158 | SDC4 1.2900 | HLA-DRA 1.2787 | HLA-E 1.2721 | CNTNAP1 1.2662 | ESAM 1.2599 | CLDN3 1.2507 | HLA-DRB3 1.2503 | SELPLG 1.2439 | SPN 1.2252 | ICOS 1.2215 | CDH1 1.2150 | ICOSLG 1.2062 | ITGB7 1.1840 | SELE 1.1773 | CLDN8 1.1715 | CLDN17 1.1407 | CLDN7 1.1371 | HLA-C 1.1295 | CD226 1.1277 | ITGB1 1.1192 | CLDN4 1.1151 | CLDN19 1.0776 | CDH15 1.0574 | SDC1 1.0557 | CTLA4 1.0433 | NRXN2 0.9962 | GLG1 0.9814 | CDH3 0.9414 | ICAM2 0.9308 | CD34 0.9161 | PVRL3 0.9077 | CLDN2 0.8826 | ITGB8 0.8819 | ITGA6 0.8763 | CLDN10 0.7506 | ITGAM 0.7270 | CLDN16 0.6937 | NLGN2 0.6604 | CLDN11 0.6198 | F11R 0.6028 | L1CAM 0.6002 | CD40LG 0.3570 | Cell adhesion molecules (CAMs) | 100294318 | CD99 | HLA-DRB4 | LOC100133583 | LOC652614 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04940 (boxplot) | 39 | 47 | 2.9042440959631497 | 0.0018407050885430598 | 0.017859965210197393 | 0.05 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | ICA1 3.4698 | FAS 3.2882 | LTA 3.0639 | TNF | PTPRN2 2.8388 | HLA-DMB 2.6120 | HLA-DQA1 2.3613 | HLA-F 2.2828 | CD28 2.1569 | HLA-DRB1 2.1516 | INS 1.9742 | CD80 1.9711 | CD86 1.9313 | IL1B 1.8813 | HLA-DRB5 1.8305 | FASLG 1.8023 | IL12A 1.7919 | PTPRN 1.7755 | HLA-DQB1 1.7437 | HLA-B 1.6543 | HSPD1 1.5925 | HLA-DOB 1.5897 | HLA-DQA2 1.5353 | HLA-G 1.5161 | HLA-DPA1 1.4883 | HLA-DPB1 | IL1A 1.4740 | HLA-A | CPE 1.4083 | HLA-DRA 1.2787 | HLA-E 1.2721 | IL2 1.2715 | HLA-DRB3 1.2503 | HLA-C 1.1295 | GAD1 1.0859 | GZMB 0.9911 | IFNG 0.8931 | GAD2 0.8924 | IL12B 0.7568 | PRF1 0.7335 | Type I diabetes mellitus | 100294318 | HLA-DRB4 | LOC100133583 | LOC652614 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04520 (boxplot) | 73 | 76 | 2.903255061043248 | 0.0018465286418057891 | 0.017859965210197393 | 0.047619047619047616 | FYN 3.7055 | ERBB2 3.2295 | INSR 3.1624 | CTNNA3 3.1603 | MAP3K7 3.1402 | ACTN3 3.1352 | EGFR 2.8090 | BAIAP2 2.7979 | PTPRM 2.7283 | CSNK2A1 2.7243 | SNAI2 2.6919 | PTPRF 2.5339 | YES1 2.4165 | IGF1R 2.4090 | CTNNA2 2.3669 | CSNK2A2 2.3563 | TCF7L1 2.3158 | FARP2 2.2728 | WASF1 2.1938 | CSNK2B 2.1620 | SMAD3 2.1433 | ACTB 2.1337 | TCF7L2 2.0892 | PTPRB 2.0671 | PARD3 2.0430 | ACTN1 2.0386 | MAPK1 1.9571 | RAC1 1.9125 | ACTG1 1.9056 | FER 1.8987 | RHOA 1.8947 | MAPK3 1.8628 | LEF1 1.7470 | WASF3 1.7392 | ACTN2 1.7215 | PVRL2 1.7152 | CREBBP 1.7131 | VCL 1.7125 | SORBS1 1.6523 | SMAD4 1.6061 | TGFBR2 1.5967 | SRC 1.5906 | FGFR1 1.5730 | PTPRJ 1.5709 | PVRL1 1.5566 | LMO7 1.5430 | EP300 1.4888 | ACTN4 1.4437 | NLK 1.4362 | PTPN1 1.4205 | ACP1 1.4136 | SNAI1 1.3990 | CTNNA1 1.3657 | IQGAP1 1.2792 | TJP1 1.2276 | CDH1 1.2150 | PTPN6 1.1681 | WASL 1.1528 | MET 1.1441 | TGFBR1 1.1193 | WAS 1.1123 | RAC2 1.0961 | CDC42 1.0907 | CTNND1 1.0729 | MLLT4 1.0402 | SMAD2 1.0065 | WASF2 0.9881 | PVRL4 0.9395 | PVRL3 0.9077 | RAC3 0.8880 | SSX2IP 0.8623 | TCF7 0.5551 | CTNNB1 0.5466 | Adherens junction | 646048 | 646821 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04666 (boxplot) | 93 | 96 | 2.903077013100222 | 0.001847578786347892 | 0.017859965210197393 | 0.045454545454545456 | CRK 4.9972 | AMPH 3.4482 | DNM3 3.4277 | INPP5D 3.1650 | DNM2 3.0383 | PRKCB 2.9939 | PLA2G4E 2.9874 | ARPC4 2.9695 | LAT 2.8728 | PRKCE 2.7354 | CFL2 2.6485 | PIK3CD 2.5941 | PIK3CG 2.5697 | PLA2G4B 2.4987 | PLCG2 2.4205 | PLA2G4A 2.3298 | CRKL 2.3083 | PLD2 2.2800 | GAB2 2.2298 | DOCK2 2.2237 | WASF1 2.1938 | PRKCA 2.1719 | SYK 2.1149 | AKT1 2.1144 | PLA2G4D 2.0990 | PIP5K1A 2.0835 | PLA2G4F 2.0368 | DNM1 2.0164 | PIK3R3 2.0057 | VAV2 1.9727 | MAPK1 1.9571 | PRKCG 1.9540 | ASAP1 1.9430 | RPS6KB2 1.9131 | RAC1 1.9125 | SPHK2 1.8974 | MAPK3 1.8628 | VAV3 1.8406 | PIK3R1 1.8351 | PIK3R5 1.7900 | MYO10 1.7867 | AKT2 1.7769 | PIP5K1B 1.7709 | PLD1 1.7651 | WASF3 1.7392 | PIP5K1C 1.7353 | RAF1 1.7090 | ARPC1A 1.7079 | ARPC1B | ASAP2 1.6780 | SCIN 1.6737 | MARCKS 1.6411 | LYN 1.5986 | FCGR2B 1.5909 | MAP2K1 1.5376 | LIMK2 1.5338 | SPHK1 1.5010 | HCK 1.4790 | PPAP2B 1.4601 | AKT3 1.4293 | PTPRC 1.4182 | PLA2G6 1.3992 | VAV1 1.3902 | VASP 1.3560 | PIK3CA 1.3325 | FCGR2A 1.2669 | CFL1 1.2636 | PIK3R2 1.2583 | RPS6KB1 1.2260 | ARPC5L 1.2241 | FCGR3A 1.2047 | FCGR2C 1.2003 | LIMK1 1.1825 | PLCG1 1.1759 | DNM1L 1.1573 | ARF6 1.1563 | WASL 1.1528 | PAK1 1.1424 | WAS 1.1123 | RAC2 1.0961 | CDC42 1.0907 | ARPC3 1.0531 | GSN 1.0374 | PPAP2A 1.0217 | NCF1 1.0210 | PRKCD 1.0164 | WASF2 0.9881 | PPAP2C 0.9653 | FCGR1A 0.9281 | PIK3CB 0.9249 | ASAP3 0.8369 | MARCKSL1 0.8048 | ARPC5 0.7879 | ARPC2 0.4034 | Fc gamma R-mediated phagocytosis | LOC653888 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04930 (boxplot) | 47 | 48 | 2.878918816743885 | 0.0019952052076732674 | 0.017859965210197393 | 0.043478260869565216 | INSR 3.1624 | MAPK9 3.1472 | TNF 3.0639 | CACNA1G 3.0242 | CACNA1C 2.8754 | PRKCE 2.7354 | PIK3CD 2.5941 | PIK3CG 2.5697 | MAFA 2.5049 | PKM2 2.3177 | GCK 2.2586 | MAPK8 2.1614 | HK1 2.1198 | CACNA1D 2.1182 | CACNA1E 2.0970 | MAPK10 2.0583 | PIK3R3 2.0057 | SOCS4 2.0014 | SOCS1 1.9877 | INS 1.9742 | MAPK1 1.9571 | CACNA1A 1.9305 | IRS1 1.9115 | MAPK3 1.8628 | CACNA1B 1.8481 | HK2 1.8360 | PIK3R1 1.8351 | IRS2 1.8084 | PRKCZ 1.7929 | PIK3R5 1.7900 | MTOR 1.7516 | ABCC8 1.7488 | SLC2A4 1.5730 | PIK3CA 1.3325 | ADIPOQ 1.3289 | HK3 1.2805 | PIK3R2 1.2583 | KCNJ11 1.1557 | SOCS3 1.1324 | SLC2A2 1.0978 | PDX1 1.0828 | IRS4 1.0252 | PRKCD 1.0164 | PIK3CB 0.9249 | PKLR 0.8529 | SOCS2 0.8180 | IKBKB 0.7521 | Type II diabetes mellitus | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa04730 (boxplot) | 68 | 71 | 2.8345231987718553 | 0.002294706281616543 | 0.017859965210197393 | 0.041666666666666664 | GNAO1 3.7443 | MAP2K2 3.3627 | GRID2 3.0003 | PRKCB 2.9939 | PLA2G4E 2.9874 | PLCB3 2.9532 | HRAS 2.6539 | PLCB1 2.6151 | GUCY1B3 2.5107 | JMJD7-PLA2G4B 2.4987 | PLA2G4B | PRKG1 2.4878 | GUCY1A3 2.4867 | IGF1R 2.4090 | GRIA3 2.4068 | PLA2G5 2.3447 | GNA12 2.3370 | PLA2G12B 2.3313 | PLA2G4A 2.3298 | NOS1 2.3035 | PPP2R1B 2.2567 | PLA2G2E 2.2318 | PRKCA 2.1719 | ITPR2 2.1594 | GRM5 1.9765 | BRAF 1.9582 | MAPK1 1.9571 | GUCY1A2 1.9560 | PRKCG 1.9540 | CACNA1A 1.9305 | PLCB2 1.8631 | MAPK3 1.8628 | PLA2G10 1.7764 | ITPR3 1.7657 | PLA2G3 1.7635 | GNAQ 1.7558 | PLA2G2A 1.7465 | RAF1 1.7090 | GRM1 1.6533 | GNAI1 1.6302 | GNA13 1.6039 | IGF1 1.6014 | LYN 1.5986 | RYR1 1.5561 | MAP2K1 1.5376 | PLA2G2F 1.4746 | GNAI3 1.4435 | ITPR1 1.4342 | PLA2G6 1.3992 | ARAF 1.3834 | PLCB4 1.3630 | CRHR1 1.3545 | GNA11 1.3379 | PRKG2 1.2488 | PLA2G2D 1.2175 | GNAS 1.1857 | GRIA1 1.1475 | PLA2G12A 1.1051 | PPP2CB 1.0588 | GNAZ 1.0149 | KRAS 0.9975 | GRIA2 0.9514 | NRAS 0.9279 | CRH 0.8287 | PPP2R1A 0.7692 | PLA2G2C 0.7622 | PPP2CA 0.6512 | GNAI2 0.5640 | PLA2G1B 0.4953 | Long-term depression | C7orf16 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa03320 (boxplot) | 67 | 70 | 2.797101844973943 | 0.00257816383417131 | 0.018840428018944186 | 0.04 | RXRB 4.6854 | ANGPTL4 3.7320 | FABP1 3.5813 | CYP4A22 3.4215 | FABP7 3.0449 | CPT1C 3.0381 | APOA1 3.0248 | APOC3 | ACOX1 2.9855 | GK2 2.8912 | RXRG 2.6680 | APOA5 2.5911 | SCD 2.5543 | SLC27A6 2.4755 | EHHADH 2.4589 | PCK1 2.3007 | ACSL1 2.2283 | SLC27A5 2.1872 | HMGCS2 2.1809 | AQP7 2.1271 | ACSL5 2.0627 | SLC27A4 1.9556 | LPL 1.9485 | CPT1B 1.8780 | SCD5 1.8770 | ACAA1 1.7773 | RXRA 1.7596 | PLTP 1.7340 | GK 1.7138 | CYP4A11 1.6857 | ACSL6 1.6845 | PPARG 1.6692 | DBI 1.6603 | SORBS1 1.6523 | ACOX3 1.6354 | SLC27A2 1.6261 | ACSL3 1.6086 | PPARD 1.5657 | CPT2 1.5335 | CD36 1.4667 | PDPK1 1.4292 | FABP3 1.4047 | UCP1 1.3977 | PLIN1 1.3583 | SCP2 1.3496 | SLC27A1 1.3359 | UBC 1.3324 | ADIPOQ 1.3289 | NR1H3 1.3265 | FABP4 1.3200 | CYP7A1 1.3148 | ACSL4 1.2837 | ME1 1.2545 | ACADL 1.2388 | MMP1 1.2208 | CPT1A 1.1834 | PCK2 1.1504 | ILK 1.1347 | FADS2 1.0437 | FABP6 1.0432 | PPARA 1.0266 | CYP8B1 1.0023 | ACADM 0.9259 | APOA2 0.8951 | ACOX2 0.8479 | CYP27A1 0.8385 | OLR1 0.8149 | FABP2 0.4716 | PPAR signaling pathway | FABP5 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05146 (boxplot) | 104 | 106 | 2.715118541767161 | 0.003312602562002498 | 0.023310906917795356 | 0.038461538461538464 | COL11A2 4.6854 | ACTN3 3.1352 | GNAL 3.0690 | TNF 3.0639 | PRKCB 2.9939 | C8A 2.9901 | PLCB3 2.9532 | PRKACB 2.9293 | LAMA3 2.9086 | COL4A2 2.8351 | SERPINB6 2.7706 | RAB5A 2.6894 | PRKX 2.6609 | PLCB1 2.6151 | PIK3CD 2.5941 | COL4A1 2.5872 | PIK3CG 2.5697 | ITGB2 2.5057 | LAMA5 2.3426 | CASP3 2.3272 | LAMA2 2.2226 | PRKCA 2.1719 | SERPINB1 2.1416 | GNA14 2.0910 | SERPINB9 2.0797 | LAMB1 2.0735 | IL1R1 2.0721 | LAMA4 2.0531 | ACTN1 2.0386 | LAMB3 2.0178 | PIK3R3 2.0057 | PRKCG 1.9540 | FN1 1.9294 | LAMC1 1.9271 | COL5A1 1.9082 | IL1B 1.8813 | GNA15 1.8776 | PLCB2 1.8631 | PIK3R1 1.8351 | CXCL1 1.8311 | LAMC2 1.8307 | HSPB1 1.8189 | MUC2 1.8188 | ARG2 1.7953 | IL12A 1.7919 | PIK3R5 1.7900 | PRKACG 1.7616 | GNAQ 1.7558 | ADCY1 1.7392 | LAMA1 1.7275 | ACTN2 1.7215 | IL6 1.7153 | VCL 1.7125 | CD14 1.6905 | COL4A4 1.6590 | RELA 1.6587 | LAMB4 1.6528 | CD1D 1.5801 | TGFB2 1.5799 | SERPINB2 1.5558 | LAMB2 1.4979 | COL1A1 1.4835 | COL3A1 1.4690 | NFKB1 1.4613 | C9 1.4511 | COL5A2 1.4504 | ACTN4 1.4437 | COL11A1 1.4339 | COL1A2 1.4123 | PTK2 1.3822 | TLR2 1.3663 | PLCB4 1.3630 | COL5A3 1.3492 | COL4A6 1.3398 | GNA11 1.3379 | PIK3CA 1.3325 | COL2A1 1.3191 | NOS2 1.3024 | RAB7A 1.3020 | IL8 1.2857 | PIK3R2 1.2583 | IL1R2 1.1993 | C8B 1.1957 | GNAS 1.1857 | LAMC3 1.1743 | RAB5B 1.1593 | SERPINB3 1.1457 | SERPINB4 1.1457 | RAB5C 1.0789 | TGFB3 1.0107 | CSF2 0.9905 | TLR4 0.9855 | TGFB1 0.9693 | PIK3CB 0.9249 | IFNG 0.8931 | C8G 0.8881 | IL10 0.8668 | IL12B 0.7568 | ITGAM 0.7270 | PRKACA 0.6979 | ARG1 0.6535 | CTSG 0.6388 | SERPINB10 0.6198 | SERPINB13 0.5944 | Amoebiasis | RAB7B | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa00512 (boxplot) | 30 | 31 | 2.626596968201943 | 0.004312170790143677 | 0.029261158933117808 | 0.037037037037037035 | GALNT13 4.0956 | WBSCR17 3.3043 | GALNTL2 2.8218 | B3GNT6 2.7492 | GALNTL1 2.7475 | GALNTL6 2.6522 | GALNT9 2.4894 | GALNT2 2.4501 | GALNT8 2.4089 | GALNTL4 2.3850 | GALNT6 2.1597 | GALNT3 2.1595 | GALNT14 2.0999 | GCNT4 1.8774 | GCNT1 1.8670 | ST3GAL1 1.8522 | B4GALT5 1.7995 | GALNTL5 1.6948 | GALNT5 1.5463 | GALNT1 1.3774 | ST3GAL2 1.3486 | C1GALT1 1.3390 | GALNT7 1.3252 | GALNT10 1.1544 | GALNT4 1.1174 | C1GALT1C1 1.0766 | GALNT12 1.0326 | GALNT11 0.8956 | GCNT3 0.6915 | ST6GALNAC1 0.6046 | O-Glycan biosynthesis | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05100 (boxplot) | 69 | 74 | 2.6198943824675758 | 0.004397850171077522 | 0.029261158933117808 | 0.03571428571428571 | CRK 4.9972 | CAV1 3.7656 | DNM3 3.4277 | CTNNA3 3.1603 | ELMO1 3.0591 | CTTN 3.0455 | DNM2 3.0383 | ARPC4 2.9695 | ARHGAP10 2.9174 | CAV2 2.8160 | PIK3CD 2.5941 | PIK3CG 2.5697 | RHOG 2.4848 | CAV3 2.3881 | CTNNA2 2.3669 | CRKL 2.3083 | WASF1 2.1938 | ACTB 2.1337 | GAB1 2.1327 | DOCK1 2.0545 | DNM1 2.0164 | PIK3R3 2.0057 | CBL 1.9784 | FN1 1.9294 | RAC1 1.9125 | ACTG1 1.9056 | RHOA 1.8947 | SHC4 1.8427 | PIK3R1 1.8351 | HCLS1 1.8175 | CLTCL1 1.8029 | PIK3R5 1.7900 | CBLB 1.7575 | SHC2 1.7321 | VCL 1.7125 | ARPC1A 1.7079 | ARPC1B | BCAR1 1.6063 | SRC 1.5906 | CBLC 1.5609 | MAD2L2 1.5156 | CLTA 1.4478 | SHC3 1.4335 | ARHGEF26 1.4139 | PTK2 1.3822 | CTNNA1 1.3657 | PIK3CA 1.3325 | SHC1 1.2933 | CLTC 1.2691 | PIK3R2 1.2583 | ARPC5L 1.2241 | CDH1 1.2150 | DNM1L 1.1573 | WASL 1.1528 | MET 1.1441 | ILK 1.1347 | ITGB1 1.1192 | WAS 1.1123 | CDC42 1.0907 | ARPC3 1.0531 | PXN 1.0115 | WASF2 0.9881 | CLTB 0.9372 | PIK3CB 0.9249 | ITGA5 0.8380 | ARPC5 0.7879 | CTNNB1 0.5466 | SEPT1 0.4455 | CD2AP 0.4312 | ARPC2 0.4034 | Bacterial invasion of epithelial cells | 646048 | 646821 | LOC653888 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05218 (boxplot) | 71 | 72 | 2.5774307438381028 | 0.004976891289740992 | 0.031520311501692946 | 0.034482758620689655 | FGF19 4.0340 | PDGFD 3.4500 | MAP2K2 3.3627 | CDKN2A 3.0353 | EGFR 2.8090 | PDGFC 2.6869 | HRAS 2.6539 | PIK3CD 2.5941 | PIK3CG 2.5697 | FGF12 2.5490 | FGF7 2.5131 | FGF13 2.4167 | IGF1R 2.4090 | FGF17 2.4040 | FGF11 2.2963 | FGF1 2.2613 | FGF23 2.2484 | FGF22 2.2464 | EGF 2.1937 | AKT1 2.1144 | CDK6 2.0335 | FGF4 2.0087 | PIK3R3 2.0057 | CCND1 1.9690 | BRAF 1.9582 | MAPK1 1.9571 | FGF9 1.8959 | MAPK3 1.8628 | FGF14 1.8434 | PIK3R1 1.8351 | FGF8 1.7956 | PIK3R5 1.7900 | AKT2 1.7769 | RAF1 1.7090 | FGF18 1.7053 | MITF 1.6908 | BAD 1.6791 | PDGFRA 1.6489 | IGF1 1.6014 | FGF5 1.6008 | FGF3 1.5781 | FGFR1 1.5730 | MAP2K1 1.5376 | PDGFA 1.5347 | CDKN1A 1.5286 | AKT3 1.4293 | PTEN 1.3846 | ARAF 1.3834 | TP53 1.3523 | PIK3CA 1.3325 | E2F3 1.3139 | CDK4 1.2985 | FGF21 1.2670 | PIK3R2 1.2583 | FGF20 1.2458 | HGF 1.2321 | PDGFRB 1.2307 | CDH1 1.2150 | RB1 1.1822 | MET 1.1441 | FGF2 1.1278 | FGF16 1.0317 | PDGFB 1.0240 | KRAS 0.9975 | FGF6 0.9927 | E2F2 0.9709 | NRAS 0.9279 | PIK3CB 0.9249 | MDM2 0.7327 | FGF10 0.7055 | E2F1 0.6669 | Melanoma | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa00230 (boxplot) | 160 | 162 | 2.5161070331248356 | 0.005932957068667921 | 0.036363285259577584 | 0.03333333333333333 | POLA1 6.3131 | PDE2A 3.7330 | POLR2H 3.5399 | ADCY10 3.5194 | PDE10A 3.5081 | NT5C 3.4358 | ADK 3.4277 | PDE4B 3.1574 | FHIT 3.1100 | PDE8A 3.0407 | APRT 3.0059 | AK5 2.9729 | PDE11A 2.9328 | PDE4D 2.8834 | PRHOXNB 2.7949 | PNP 2.7166 | GUCY2D 2.6485 | GUCY2C 2.6418 | PPAT 2.6276 | PDE7B 2.6103 | ADCY5 2.5811 | POLR3F 2.5747 | ADCY2 2.5386 | GUCY1B3 2.5107 | ENTPD6 2.5066 | GUCY1A3 2.4867 | NT5C1B 2.3958 | PDE3A 2.3821 | PGM1 2.3707 | AK7 2.3456 | PKM2 2.3177 | ITPA 2.3045 | XDH 2.2615 | PDE6C 2.2565 | GUK1 2.2368 | POLE3 2.2350 | ALLC 2.2060 | PDE1C 2.1963 | PRUNE 2.1770 | ADCY3 2.1650 | PAPSS2 2.1647 | POLE2 2.1436 | GMPR 2.1131 | ENTPD2 2.0879 | PNPT1 2.0485 | AMPD2 2.0473 | NUDT9 1.9892 | GUCY1A2 1.9560 | POLR2E 1.9538 | POLR3G 1.9487 | POLR3B 1.9387 | PGM2 1.9257 | POLR3A 1.9173 | NT5C1A 1.9097 | POLR3K 1.8896 | ZNRD1 1.8731 | POLR3GL 1.8599 | NT5C2 1.8235 | POLR1D 1.8224 | POLR3D 1.8165 | IMPDH2 1.8077 | ENTPD1 1.7988 | PDE9A 1.7763 | POLR2L 1.7743 | NME3 1.7605 | ADCY9 1.7405 | ADCY1 1.7392 | AK1 1.7279 | AK4 1.7279 | ADCY8 1.7139 | PDE3B 1.7081 | NME6 1.6957 | POLD2 1.6500 | POLR3C 1.6400 | PAICS 1.6241 | NME5 1.6035 | NUDT5 1.5956 | ENPP3 1.5651 | NME1 1.5583 | NME1-NME2 | ATIC 1.5516 | PDE6A 1.5259 | PDE1A 1.5160 | POLR1C 1.4944 | PAPSS1 1.4777 | NME2 1.4706 | PRIM2 1.4553 | ADCY4 1.4548 | NME4 1.4514 | DCK 1.4347 | PDE4C 1.4334 | ADA 1.4333 | IMPDH1 1.4289 | ADCY7 1.4224 | PDE6H 1.3989 | POLR1A 1.3815 | PDE8B 1.3712 | ADSSL1 1.3671 | AMPD3 1.3511 | POLA2 1.3369 | NPR1 1.3340 | POLR2B 1.3262 | PRPS2 1.3147 | POLD3 1.2925 | ENTPD4 1.2769 | ENTPD3 1.2522 | PDE7A 1.2485 | NUDT2 1.2442 | GUCY2F 1.2384 | ENPP1 1.1901 | PDE1B 1.1847 | NT5C3 1.1841 | POLR3H 1.1726 | POLD1 1.1632 | PDE6B 1.1598 | CANT1 1.1564 | NT5M 1.1487 | POLR1E 1.1465 | NT5E 1.1463 | C17orf48 1.1438 | PDE5A 1.1185 | POLR2A 1.1129 | PRPS1L1 1.1035 | POLD4 1.1031 | POLR2G 1.0971 | POLR2D 1.0905 | POLE 1.0804 | PDE6G 1.0776 | PDE6D 1.0743 | ADSL 1.0704 | AK2 1.0468 | GMPR2 1.0126 | DGUOK 0.9941 | POLR2K 0.9675 | NPR2 0.9581 | RRM1 0.9485 | POLR2I 0.9405 | AMPD1 0.9279 | POLR2J 0.9216 | RRM2 0.9109 | PFAS 0.9081 | GART 0.8769 | RRM2B 0.8716 | PKLR 0.8529 | GMPS 0.8402 | ENTPD5 0.8155 | ENTPD8 0.8155 | HPRT1 0.8115 | ADSS 0.7750 | POLR2F 0.7730 | ADCY6 0.7536 | PDE4A 0.7502 | NME7 0.7358 | PRPS1 0.6901 | POLR2J2 0.6737 | POLR2J3 0.6737 | POLR1B 0.6651 | PRIM1 0.6558 | POLE4 0.6505 | GDA 0.6345 | POLR2C 0.4547 | Purine metabolism | ||||||||||||||||||||||||||||||||||||||||
hsa05213 (boxplot) | 52 | 53 | 2.4460321340809945 | 0.00722190632258668 | 0.04288006879035841 | 0.03225806451612903 | GRB2 3.5564 | MAP2K2 3.3627 | ERBB2 3.2295 | CTNNA3 3.1603 | EGFR 2.8090 | HRAS 2.6539 | PIK3CD 2.5941 | PIK3CG 2.5697 | APC2 2.3743 | CTNNA2 2.3669 | TCF7L1 2.3158 | EGF 2.1937 | AKT1 2.1144 | TCF7L2 2.0892 | FOXO3 2.0675 | PIK3R3 2.0057 | AXIN1 1.9756 | CCND1 1.9690 | BRAF 1.9582 | MYC 1.9575 | MAPK1 1.9571 | MAPK3 1.8628 | PIK3R1 1.8351 | PIK3R5 1.7900 | AKT2 1.7769 | LEF1 1.7470 | RAF1 1.7090 | ELK1 1.6910 | BAD 1.6791 | CASP9 1.5727 | MAP2K1 1.5376 | SOS2 1.5227 | APC 1.5096 | AKT3 1.4293 | PDPK1 1.4292 | PTEN 1.3846 | ARAF 1.3834 | AXIN2 1.3665 | CTNNA1 1.3657 | TP53 1.3523 | PIK3CA 1.3325 | MLH1 1.3098 | PIK3R2 1.2583 | CDH1 1.2150 | GSK3B 1.1968 | SOS1 1.1496 | ILK 1.1347 | KRAS 0.9975 | NRAS 0.9279 | PIK3CB 0.9249 | TCF7 0.5551 | CTNNB1 0.5466 | Endometrial cancer | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05332 (boxplot) | 37 | 45 | 2.4134981814611005 | 0.007900103366187516 | 0.04548544362350388 | 0.03125 | HLA-DMA 4.6143 | HLA-DOA 4.4996 | FAS 3.2882 | TNF 3.0639 | KLRD1 2.7479 | HLA-DMB 2.6120 | HLA-DQA1 2.3613 | HLA-F 2.2828 | CD28 2.1569 | HLA-DRB1 2.1516 | CD80 1.9711 | KLRC1 1.9399 | CD86 1.9313 | IL1B 1.8813 | HLA-DRB5 1.8305 | FASLG 1.8023 | HLA-DQB1 1.7437 | IL6 1.7153 | HLA-B 1.6543 | HLA-DOB 1.5897 | HLA-DQA2 1.5353 | KIR3DL2 1.5266 | HLA-G 1.5161 | HLA-DPA1 1.4883 | HLA-DPB1 | KIR3DL1 1.4758 | IL1A 1.4740 | HLA-A | HLA-DRA 1.2787 | HLA-E 1.2721 | IL2 1.2715 | HLA-DRB3 1.2503 | HLA-C 1.1295 | GZMB 0.9911 | KIR2DL5A 0.9653 | KIR2DL1 0.9172 | KIR2DL3 | IFNG 0.8931 | PRF1 0.7335 | KIR2DL2 0.6972 | Graft-versus-host disease | 100294318 | HLA-DRB4 | LOC100133583 | LOC652614 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa05410 (boxplot) | 83 | 86 | 2.400470707319119 | 0.008187000607648653 | 0.04575088574862483 | 0.030303030303030304 | PRKAG2 3.7137 | DMD 3.6492 | RYR2 3.1737 | CACNB4 3.1376 | TNF 3.0639 | SGCG 3.0172 | CACNA1C 2.8754 | SLC8A1 2.7718 | ITGA2 2.6856 | CACNG3 2.6709 | ITGA1 2.5638 | ITGA9 2.5201 | TPM3 2.4781 | TTN 2.4386 | SGCD 2.3072 | CACNG4 2.2546 | LAMA2 2.2226 | CACNB2 2.2123 | ITGB3 2.1729 | ACTB 2.1337 | CACNA1D 2.1182 | ITGB5 2.0784 | TNNI3 2.0145 | ITGA10 2.0120 | CACNA2D1 1.9982 | CACNA2D3 1.9648 | CACNG7 1.9540 | ITGA8 1.9537 | MYBPC3 1.9461 | ITGB6 1.9218 | ACTG1 1.9056 | SGCB 1.8841 | MYL3 1.8709 | PRKAA2 1.8703 | TNNC1 1.8440 | CACNG1 1.8336 | MYH6 1.8142 | MYH7 1.8142 | SGCA 1.7693 | ITGAV 1.7509 | ITGA11 1.7210 | IL6 1.7153 | CACNA2D2 1.6959 | CACNG6 1.6930 | ATP2A2 1.6834 | ITGA4 1.6794 | CACNG5 1.6745 | IGF1 1.6014 | TPM1 1.5971 | TGFB2 1.5799 | MYL2 1.5502 | ITGA2B 1.5355 | CACNA2D4 1.4192 | CACNA1S 1.3954 | CACNG2 1.3692 | DES 1.3358 | ITGA3 1.3270 | TPM4 1.3177 | CACNG8 1.2699 | TNNT2 1.2243 | TPM2 1.1946 | ITGB7 1.1840 | CACNB1 1.1775 | ITGA7 1.1296 | ITGB1 1.1192 | PRKAG1 1.1069 | ACTC1 1.1031 | PRKAB2 1.0760 | LMNA 1.0722 | PRKAG3 1.0632 | PRKAB1 1.0322 | TGFB3 1.0107 | TGFB1 0.9693 | CACNA1F 0.9583 | ITGB4 0.8918 | ITGB8 0.8819 | ITGA6 0.8763 | ITGA5 0.8380 | ACE 0.7753 | PRKAA1 0.7726 | CACNB3 0.7536 | EMD 0.7196 | DAG1 0.6937 | Hypertrophic cardiomyopathy (HCM) | 646048 | 646821 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hsa00603 (boxplot) | 14 | 15 | 2.387448866279833 | 0.00848288134801023 | 0.04604992731776982 | 0.029411764705882353 | GLA 3.9934 | HEXA 3.0328 | ST8SIA1 2.8007 | B3GALNT1 2.7281 | FUT9 2.3791 | HEXB 2.3391 | ST3GAL1 1.8522 | FUT2 1.6736 | A4GALT 1.5256 | NAGA 1.3816 | ST3GAL2 1.3486 | FUT1 1.1603 | B3GALT5 1.1305 | GBGT1 0.9052 | Glycosphingolipid biosynthesis - globo series |