pval<0.1	(1845*0.1)/371	fdr=0.4973045822102426
pval<0.05	(1845*0.05)/224	fdr=0.41183035714285715
pval<0.01	(1845*0.01)/54	fdr=0.3416666666666667
pval<0.0010	(1845*0.0010)/3	fdr=0.615
pval<1.0E-4	(1845*1.0E-4)/1	fdr=0.1845