pval<0.1	(1845*0.1)/321	fdr=0.5747663551401869
pval<0.05	(1845*0.05)/185	fdr=0.49864864864864866
pval<0.01	(1845*0.01)/46	fdr=0.4010869565217391
pval<0.0010	(1845*0.0010)/5	fdr=0.369
pval<1.0E-4	(1845*1.0E-4)/1	fdr=0.1845