| Tuesday 1st July 2003 |
|
| 11 am | Registration, coffee and sandwiches |
|
| 1 pm | Ariel Darvasi | Genetic dissection of
common diseases in the post-genomic era |
| Mouse Haplotype Structure |
| 1.20 pm | Mark Daly | A Haplotype Map of
the Laboratory Mouse: Acceleration of Positional Cloning |
| 1.40 pm | Matthew Pletcher | Generation of a SNP-based mouse
haplotype map |
| 2.00 pm | Jinguiz Zhang | A multi-strain, high-resolution mouse haplotype map reveals the heterogeneity of mouse haplotype block structure |
|
| 2.20 pm | Break |
|
| Heterogenous Stocks |
|
| 2.40 pm | Leah Solberg | A multi-phenotype procedure
for fine scale mapping of QTL in outbred heterogeneous stock mice |
| 3.00 pm | Binnaz Yalcin | Detailed genetic characterization of an anxiety susceptibility QTL in mouse model : how far are we from discovering a QT gene? |
| 3.20 pm | Sarah Lloyd | Quantitative trait locus analysis of prion disease incubation time in mice |
| 3.40 pm | William Valdar | QTL fine-mapping with Recombinant-Inbred Heterogeneous Stocks and In-Vitro Heterogeneous Stocks |
|
| 4.00 pm | Break | |
|
| Expression-based QTL studies |
| 4.20 pm | Tim Aitman | Genome Resources and Identification of Complex
Trait Genes |
| 4.40 pm | David Threadgill | Allelic series and extreme background dependent genetic
heterogeneity associated with alterations in epidermal growth factor receptor
signaling. |
| 5.00 pm | Leo Schalkwyk | Hippocampal
gene expression profiling across eight mouse strains: towards understanding the
molecular basis for behaviour |
| 5.20 pm | Elizabeth Simpson | Towards QTL Mapping
& Microarrays to Identify Modifiers of Caspase 3
Induced Exencephaly |
|
| 5.40 - 7 pm | Buffet Supper | |
|
| Strategies for QTL mapping |
| 7pm | Ken Paigen | Some considerations regarding program content
and strategy |
| 7.20pm - 9.00 pm | Robert Williams and Others | Discussion of Collaborative Cross |
|
| Wednesday 2nd July |
|
| Cancer QTLs |
| 9.00 am | Bruce Ponder (Keynote) | Polygenes and the prevention of cancer |
| 10.00 am | Peter Demant | Colon and Lung Cancer Susceptibility - Interactions, Genes and Malignant Progression |
| 10.20 am | Allan Balmain | Identification of Aurora2/Stk6/STK15
as a candidate low penetrance tumor susceptibility
gene in mouse and man
|
| 10.40 am | Joe Angel | Genetics of Promotion Susceptibility in the Two-Stage Skin Tumor
Model |
|
| 10.40 am | Break | |
|
| Integrated approaches to QTL mapping |
| 11.00 am | Kent Hunter | Integrative multi-dimensional transomic analysis
strategies reveal novel insights into potentially important molecular pathways
for mammary tumor dissemination |
| 11.20 am | Robert Hitzemann | On the Integration of QTL, gene expression and sequence analysis |
| 11.40 am | Fuad Iraqi | Multiple approaches for dissecting quantitative
trait loci and cloning the underlying genes |
| 12 noon | Leonid Bystrykh | Genetical Genomics to
Identify Gene Pathways Regulating Hematopoietic Stem Cells |
|
| 12.20 pm | Lunch | |
|
| Theoretical Studies |
| 1.40 pm | Andrew Morris | Bayesian MCMC QTL mapping in outbred mice |
| 2.00 pm | Mikko Sillanpaa | Bayesian Analysis of Multilocus Association in Quantitative and Binary Traits |
| 2.20 pm | Chris Klingenberg | Morphological integration
in the mouse mandible: multivariate analysis of QTL effects |
| 2.40 pm | Alexander Osadchuk | A novel approach to genetically dissect
complex quantitative traits using a diallel cross of recombinant inbred strains |
|
| 3.00 pm | Break | |
|
|
| Recombinant Inbred Lines |
|
| 3.20 pm | Elissa Chesler | Genetic correlations and associative networks for CNS transcript
abundance and neurobehavioral phenotypes in a recombinant inbred mapping panel.
|
| 3.40 pm | Ken Manly | WebQTL: Complex trait analysis beyond QTL
mapping |
| 4.00 pm | Dirk-Jan de Koning | Epistatic QTL for gene expression in mice;
potential for BXD expression data |
|
| 4.20 pm | Break | |
|
| QTL and ENU Studies |
|
| 4.40 pm | Roger Cox | Type 2 Diabetes- A complex trait |
| 5.00 pm | Alexander Bachmanov | Genetic dissection of sweet taste |
| 5.20 pm | Richard Nowakowski | Strain Differences in Stem/Progenitor Cell
Proliferation and Survival DuringAdult in the Dentate Gyrus |
|
| 7.00 pm | Conference dinner | |
|
| Thursday 3rd July |
|
|
| Congenics and Consomics |
|
| 9.00 am | Jiri Forejt | Inter-species consomic
strains and accompanying tools for mapping and identification of quantitative
trait loci |
| 9.20 am | Dominique Gauguier | Congenic-based strategies for dissecting the
architecture of QTL and their biological functions |
| 9.40 pm | Lutz Bunger | Mouse lines,
long-term selected on growth, fatness and metabolic rate - a unique resource
for the genetic dissection of QT’s |
|
| 10.00 am | Break | |
|
| QTL mapping Resources |
| 10.20 am | Molly Bogue | Mouse Phenome
Database: Research tool and data resource |
| 10.40 am | Jeff Christiansen | EMAGE – The Edinburgh
Mouse Atlas of Gene Expression |
|
| Epistasis |
|
| 11.00 am | Orjan Carlborg | The Role of Epistasis in the Control of Complex Traits |
| 11.20 am | Kajsa Ljungberg | An algorithm for simultaneous search for multiple QTL |
| 11.40 am | | Concluding Remarks |
|
| 12.00 noon | Lunch | |
|