Complex Trait Consortium. Oxford 1-3 July 2003

Provisional Agenda

Tuesday 1st July 2003
11 am Registration, coffee and sandwiches
1 pm Ariel DarvasiGenetic dissection of common diseases in the post-genomic era
Classical QTL mapping
1.20 pm Lutz BungerMouse lines, long-term selected on growth, fatness and metabolic rate - a unique resource for the genetic dissection of QT’s
1.40 pm Dominique GauguierCongenic-based strategies for dissecting the architecture of QTL and their biological functions
2.00 pm Roger CoxType 2 Diabetes- A complex trait
2.20 pm Break
2.40 pm Jiri ForejtInter-species consomic strains and accompanying tools for mapping and identification of quantitative trait loci
3.00 pm Joe AngelGenetics of Promotion Susceptibility in the Two-Stage Skin Tumor Model
3.20 pm Alexander BachmanovGenetic dissection of sweet taste
3.40 pm Chris KlingenbergMorphological integration in the mouse mandible: multivariate analysis of QTL effects
4.00 pm Break
Integrated approaches to QTL mapping
4.20 pm Robert HitzemanOn the Integration of QTL, gene expression and sequence analysis
4.40 pm Kent HunterIntegrative multi-dimensional transomic analysis strategies reveal novel insights into potentially important molecular pathways for mammary tumor dissemination
5.00 pm Fuad Iraqi Multiple approaches for dissecting quantitative trait loci and cloning the underlying genes
5.40 pm William Valdar
6 - 7 pm Buffet Supper
Strategies for QTL mapping
7pm Ken Paigen Some considerations regarding program content and strategy
7.20pm - 9pmRobert Williams and Others Discussion of Collaborative Cross
Wednesday 2nd July
9 am Bruce Ponder (Keynote) Polygenes and the prevention of cancer
Theoretical Studies
10 am Orjan Carlborg The Role of Epistasis in the Control of Complex Traits
10.20 am Kajsa Ljungberg An algorithm for simultaneous search for multiple QTL
10.40 am Break
11 am Alexander Osadchuk A novel approach to genetically dissect complex quantitative traits using a diallel cross of recombinant inbred strains
11.20 am Mikko Sillanpaa Bayesian Analysis of Multilocus Association in Quantitative and Binary Traits
11.40 am Andrew Morris Bayesian MCMC QTL mapping in outbred mice
12 noon Yoav Benjamani A statisticians point of view on the significance of QTL
12.20 pm Lunch
Expression-based QTL studies
1.40 pm Tim Aitman Genome Resources and Identification of Complex Trait Genes
2.00 pm Leonid Bystrykh Genetical Genomics to Identify Gene Pathways Regulating Hematopoietic Stem Cells
2.20 pm Leo Schalkwyk Hippocampal gene expression profiling across eight mouse strains: towards understanding the molecular basis for behaviour
2.40 pm Elizabeth Simpson Towards QTL Mapping & Microarrays to Identify Modifiers of Caspase 3 Induced Exencephaly
3.00 pm David Threadgill Allelic series and extreme background dependent genetic heterogeneity associated with alterations in epidermal growth factor receptor signaling.
3.20 pm Break
Heterogenous Stock and Recombinant Inbred QTL studies
3.40 pm Sarah Lloyd Quantitative trait locus analysis of prion disease incubation time in mice
4.00 pm Richard Nowakowski Strain Differences in Stem/Progenitor Cell Proliferation and Survival DuringAdult in the Dentate Gyrus
4.20 pm Binnaz Yalcin
4.40 pm Leah Solberg A multi-phenotype procedure for fine scale mapping of QTL in outbred heterogeneous stock mice
5.00 pm Dirk-Jan de Koning QTL for gene expression in mice; potential for BXD expression data
7.00 pm Conference dinner
Thursday 3rd July
QTL mapping Resources
9.00 am Mark DalyA Haplotype Map of the Laboratory Mouse: Acceleration of Positional Cloning
9.20 am Molly BogueMouse Phenome Database: Research tool and data resource
9.40 am Jeff ChristiansenEMAGE – The Edinburgh Mouse Atlas of Gene Expression
10.00 am Ken ManlyWebQTL: Complex trait analysis beyond QTL mapping
10.20 am Break
10.40 amLeena Peltonen
11.00 amAllan Balmain
11.20 amPeter Demant
11.40 amElissa Chesler Genetic correlations and associative networks for CNS transcript abundance and neurobehavioral phenotypes in a recombinant inbred mapping panel.
12 noonJinguiz ZhangA multi-strain, high-resolution mouse haplotype map reveals the heterogeneity of mouse haplotype block structure
12.20 pm Lunch
 
spacer